Details of the Target

General Information of Target

Target ID LDTP01465
Target Name Glutaminase kidney isoform, mitochondrial (GLS)
Gene Name GLS
Gene ID 2744
Synonyms
GLS1; KIAA0838; Glutaminase kidney isoform, mitochondrial; GLS; EC 3.5.1.2; K-glutaminase; L-glutamine amidohydrolase) [Cleaved into: Glutaminase kidney isoform, mitochondrial 68 kDa chain; Glutaminase kidney isoform, mitochondrial 65 kDa chain]
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MMRLRGSGMLRDLLLRSPAGVSATLRRAQPLVTLCRRPRGGGRPAAGPAAAARLHPWWGG
GGWPAEPLARGLSSSPSEILQELGKGSTHPQPGVSPPAAPAAPGPKDGPGETDAFGNSEG
KELVASGENKIKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMD
MLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKK
QSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDL
GTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQ
FLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSI
EVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPA
KSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKL
DPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVE
VVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQT
VHKNLDGLL
Target Bioclass
Enzyme
Family
Glutaminase family
Subcellular location
Mitochondrion; Mitochondrion matrix
Function
Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate, the main excitatory neurotransmitter in the brain.; [Isoform 2]: Lacks catalytic activity.
Uniprot ID
O94925
Ensemble ID
ENST00000320717.8
HGNC ID
HGNC:4331
ChEMBL ID
CHEMBL2146302

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HT115 SNV: p.R272M; p.R454Ter DBIA    Probe Info 
LS180 SNV: p.D634G DBIA    Probe Info 
NCIH358 SNV: p.G243E DBIA    Probe Info 
SKNSH SNV: p.K85N .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 36 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
N1
 Probe Info  		100.00  LDD0242  [1]
TH211
 Probe Info  		Y308(20.00); Y370(20.00); Y249(18.31); Y304(13.68)  LDD0257  [2]
TH214
 Probe Info  		Y308(10.08)  LDD0258  [2]
TH216
 Probe Info  		Y293(20.00); Y308(20.00); Y357(20.00); Y249(19.98)  LDD0259  [2]
YN-1
 Probe Info  		100.00  LDD0444  [3]
ONAyne
 Probe Info  		K311(1.58)  LDD0274  [4]
STPyne
 Probe Info  		K130(5.19); K158(8.56); K164(4.75); K176(5.33)  LDD0277  [4]
IPM
 Probe Info  		C518(0.00); C525(0.00); C203(0.00); C178(0.00)  LDD0241  [5]
Probe 1
 Probe Info  		Y370(8.68)  LDD3495  [6]
BTD
 Probe Info  		C178(0.73)  LDD2091  [7]
AHL-Pu-1
 Probe Info  		C266(8.51)  LDD0170  [8]
HPAP
 Probe Info  		3.13  LDD0064  [9]
HHS-482
 Probe Info  		Y304(0.35)  LDD0286  [10]
HHS-475
 Probe Info  		Y394(0.93); Y304(5.10); Y145(6.02)  LDD0264  [11]
DBIA
 Probe Info  		C525(1.11)  LDD0078  [12]
5E-2FA
 Probe Info  		H519(0.00); H89(0.00)  LDD2235  [13]
ATP probe
 Probe Info  		K164(0.00); K320(0.00); K328(0.00)  LDD0199  [14]
m-APA
 Probe Info  		N.A.  LDD2231  [13]
1d-yne
 Probe Info  		K132(0.00); K218(0.00)  LDD0358  [15]
4-Iodoacetamidophenylacetylene
 Probe Info  		C203(0.00); C178(0.00); C609(0.00); C266(0.00)  LDD0038  [16]
IA-alkyne
 Probe Info  		C266(0.00); C203(0.00)  LDD0032  [17]
Lodoacetamide azide
 Probe Info  		C203(0.00); C609(0.00); C266(0.00); C178(0.00)  LDD0037  [16]
TFBX
 Probe Info  		N.A.  LDD0027  [18]
WYneN
 Probe Info  		N.A.  LDD0021  [19]
NHS
 Probe Info  		N.A.  LDD0010  [19]
PF-06672131
 Probe Info  		N.A.  LDD0017  [20]
SF
 Probe Info  		Y394(0.00); Y304(0.00); K164(0.00)  LDD0028  [21]
Phosphinate-6
 Probe Info  		C518(0.00); C287(0.00); C463(0.00); C266(0.00)  LDD0018  [22]
1c-yne
 Probe Info  		K320(0.00); K328(0.00); K255(0.00)  LDD0228  [15]
Acrolein
 Probe Info  		C266(0.00); H89(0.00); H516(0.00)  LDD0217  [23]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [23]
Methacrolein
 Probe Info  		C266(0.00); C178(0.00)  LDD0218  [23]
W1
 Probe Info  		C283(0.00); C287(0.00); C266(0.00); C178(0.00)  LDD0236  [5]
AOyne
 Probe Info  		6.50  LDD0443  [24]
NAIA_5
 Probe Info  		C203(0.00); C266(0.00); C500(0.00); C287(0.00)  LDD2223  [25]
HHS-465
 Probe Info  		K164(0.00); K396(0.00); Y394(0.00); K153(0.00)  LDD2240  [26]
PAL-AfBPP Probe
Click To Hide/Show 8 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C134
 Probe Info  		20.53  LDD1816  [27]
C158
 Probe Info  		11.08  LDD1838  [27]
C278
 Probe Info  		50.91  LDD1948  [27]
FFF probe13
 Probe Info  		12.38  LDD0475  [28]
FFF probe2
 Probe Info  		6.70  LDD0463  [28]
STS-1
 Probe Info  		1.79  LDD0137  [29]
STS-2
 Probe Info  		N.A.  LDD0138  [29]
VE-P
 Probe Info  		N.A.  LDD0396  [30]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C178(1.12)  LDD2117  [7]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C178(1.44)  LDD2152  [7]
 LDCM0025  4SU-RNA DM93 C266(8.51)  LDD0170  [8]
 LDCM0026  4SU-RNA+native RNA DM93 C266(12.87)  LDD0171  [8]
 LDCM0214  AC1 HCT 116 C178(1.82); C203(0.83); C266(0.88); C283(0.86)  LDD0531  [12]
 LDCM0215  AC10 HCT 116 C178(1.45); C203(0.79); C266(0.81); C283(1.05)  LDD0532  [12]
 LDCM0216  AC100 HCT 116 C203(1.56); C266(0.69); C283(1.10); C287(1.16)  LDD0533  [12]
 LDCM0217  AC101 HCT 116 C203(1.09); C266(0.76); C283(1.06); C287(0.94)  LDD0534  [12]
 LDCM0218  AC102 HCT 116 C203(1.20); C266(0.66); C283(1.13); C287(1.16)  LDD0535  [12]
 LDCM0219  AC103 HCT 116 C203(1.12); C266(0.62); C283(1.21); C287(1.12)  LDD0536  [12]
 LDCM0220  AC104 HCT 116 C203(1.18); C266(0.55); C283(1.15); C287(1.20)  LDD0537  [12]
 LDCM0221  AC105 HCT 116 C203(1.02); C266(0.70); C283(1.12); C287(1.12)  LDD0538  [12]
 LDCM0222  AC106 HCT 116 C203(1.55); C266(0.71); C283(1.08); C287(1.13)  LDD0539  [12]
 LDCM0223  AC107 HCT 116 C203(1.20); C266(0.84); C283(1.17); C287(1.19)  LDD0540  [12]
 LDCM0224  AC108 HCT 116 C203(1.21); C266(0.63); C283(1.00); C287(1.09)  LDD0541  [12]
 LDCM0225  AC109 HCT 116 C203(1.30); C266(0.86); C283(1.19); C287(1.37)  LDD0542  [12]
 LDCM0226  AC11 HCT 116 C178(1.52); C203(0.75); C266(0.81); C283(0.91)  LDD0543  [12]
 LDCM0227  AC110 HCT 116 C203(1.38); C266(0.71); C283(1.02); C287(1.04)  LDD0544  [12]
 LDCM0228  AC111 HCT 116 C203(1.46); C266(0.57); C283(1.10); C287(1.12)  LDD0545  [12]
 LDCM0229  AC112 HCT 116 C203(1.19); C266(0.63); C283(1.02); C287(1.05)  LDD0546  [12]
 LDCM0230  AC113 HCT 116 C203(0.66); C266(0.97); C283(0.92); C287(0.97)  LDD0547  [12]
 LDCM0231  AC114 HCT 116 C203(0.81); C266(1.07); C283(0.73); C287(0.70)  LDD0548  [12]
 LDCM0232  AC115 HCT 116 C203(0.62); C266(1.06); C283(0.59); C287(0.55)  LDD0549  [12]
 LDCM0233  AC116 HCT 116 C203(0.58); C266(0.86); C283(0.55); C287(0.52)  LDD0550  [12]
 LDCM0234  AC117 HCT 116 C203(0.75); C266(0.87); C283(0.72); C287(0.66)  LDD0551  [12]
 LDCM0235  AC118 HCT 116 C203(1.15); C266(0.93); C283(0.78); C287(0.75)  LDD0552  [12]
 LDCM0236  AC119 HCT 116 C203(0.67); C266(1.04); C283(0.61); C287(0.59)  LDD0553  [12]
 LDCM0237  AC12 HCT 116 C178(1.46); C203(0.84); C266(1.08); C283(1.10)  LDD0554  [12]
 LDCM0238  AC120 HCT 116 C203(0.61); C266(1.01); C283(0.82); C287(0.77)  LDD0555  [12]
 LDCM0239  AC121 HCT 116 C203(1.08); C266(0.97); C283(0.95); C287(0.94)  LDD0556  [12]
 LDCM0240  AC122 HCT 116 C203(0.82); C266(1.08); C283(0.75); C287(0.73)  LDD0557  [12]
 LDCM0241  AC123 HCT 116 C203(1.15); C266(0.90); C283(1.17); C287(1.08)  LDD0558  [12]
 LDCM0242  AC124 HCT 116 C203(1.17); C266(1.13); C283(0.96); C287(0.92)  LDD0559  [12]
 LDCM0243  AC125 HCT 116 C203(0.93); C266(1.00); C283(0.80); C287(0.79)  LDD0560  [12]
 LDCM0244  AC126 HCT 116 C203(0.68); C266(1.01); C283(0.68); C287(0.67)  LDD0561  [12]
 LDCM0245  AC127 HCT 116 C203(0.75); C266(0.97); C283(0.66); C287(0.64)  LDD0562  [12]
 LDCM0246  AC128 HCT 116 C178(0.76); C203(0.92); C266(0.90); C283(1.65)  LDD0563  [12]
 LDCM0247  AC129 HCT 116 C178(0.76); C203(1.03); C266(1.36); C283(1.29)  LDD0564  [12]
 LDCM0249  AC130 HCT 116 C178(0.66); C203(0.91); C266(0.98); C283(1.21)  LDD0566  [12]
 LDCM0250  AC131 HCT 116 C178(0.67); C203(1.06); C266(1.23); C283(1.43)  LDD0567  [12]
 LDCM0251  AC132 HCT 116 C178(0.87); C203(1.11); C266(1.34); C283(1.02)  LDD0568  [12]
 LDCM0252  AC133 HCT 116 C178(0.54); C203(1.11); C266(1.04); C283(1.16)  LDD0569  [12]
 LDCM0253  AC134 HCT 116 C178(0.71); C203(1.00); C266(1.17); C283(1.49)  LDD0570  [12]
 LDCM0254  AC135 HCT 116 C178(0.60); C203(1.06); C266(0.81); C283(1.26)  LDD0571  [12]
 LDCM0255  AC136 HCT 116 C178(1.04); C203(1.06); C266(0.95); C283(1.29)  LDD0572  [12]
 LDCM0256  AC137 HCT 116 C178(0.89); C203(1.11); C266(1.29); C283(1.36)  LDD0573  [12]
 LDCM0257  AC138 HCT 116 C178(1.51); C203(1.03); C266(1.00); C283(1.78)  LDD0574  [12]
 LDCM0258  AC139 HCT 116 C178(0.74); C203(0.85); C266(0.92); C283(1.13)  LDD0575  [12]
 LDCM0259  AC14 HCT 116 C178(1.36); C203(0.79); C266(0.77); C283(1.42)  LDD0576  [12]
 LDCM0260  AC140 HCT 116 C178(0.66); C203(1.07); C266(0.85); C283(1.33)  LDD0577  [12]
 LDCM0261  AC141 HCT 116 C178(0.82); C203(1.00); C266(0.96); C283(1.42)  LDD0578  [12]
 LDCM0262  AC142 HCT 116 C178(20.00); C203(1.26); C266(1.55); C283(1.10)  LDD0579  [12]
 LDCM0263  AC143 HCT 116 C178(0.80); C203(0.78); C266(0.96); C283(0.89)  LDD0580  [12]
 LDCM0264  AC144 HCT 116 C203(0.51); C266(0.56); C525(0.64); C518(0.68)  LDD0581  [12]
 LDCM0265  AC145 HCT 116 C525(0.65); C203(0.84); C518(0.86); C178(1.09)  LDD0582  [12]
 LDCM0266  AC146 HCT 116 C266(0.65); C525(0.66); C203(0.66); C518(0.70)  LDD0583  [12]
 LDCM0267  AC147 HCT 116 C203(0.55); C525(0.61); C266(0.76); C283(0.77)  LDD0584  [12]
 LDCM0268  AC148 HCT 116 C525(0.46); C203(0.62); C266(0.72); C518(0.79)  LDD0585  [12]
 LDCM0269  AC149 HCT 116 C266(0.46); C203(0.61); C525(0.66); C283(0.75)  LDD0586  [12]
 LDCM0270  AC15 HCT 116 C266(0.74); C203(0.76); C609(1.06); C287(1.20)  LDD0587  [12]
 LDCM0271  AC150 HCT 116 C203(0.79); C525(0.80); C283(0.86); C518(0.88)  LDD0588  [12]
 LDCM0272  AC151 HCT 116 C266(0.66); C525(0.70); C283(0.77); C518(0.81)  LDD0589  [12]
 LDCM0273  AC152 HCT 116 C525(0.50); C203(0.50); C266(0.61); C518(0.67)  LDD0590  [12]
 LDCM0274  AC153 HCT 116 C525(0.59); C203(0.65); C518(0.75); C266(0.79)  LDD0591  [12]
 LDCM0621  AC154 HCT 116 C178(1.29); C203(0.70); C266(0.82); C283(0.99)  LDD2158  [12]
 LDCM0622  AC155 HCT 116 C178(1.08); C203(0.61); C266(0.61); C283(0.81)  LDD2159  [12]
 LDCM0623  AC156 HCT 116 C178(1.04); C203(1.81); C266(0.75); C283(0.95)  LDD2160  [12]
 LDCM0624  AC157 HCT 116 C178(1.03); C203(0.85); C266(1.12); C283(1.30)  LDD2161  [12]
 LDCM0276  AC17 HCT 116 C266(0.81); C518(0.81); C525(0.81); C609(0.93)  LDD0593  [12]
 LDCM0277  AC18 HCT 116 C609(0.56); C518(0.64); C525(0.64); C266(0.67)  LDD0594  [12]
 LDCM0278  AC19 HCT 116 C609(0.80); C266(0.83); C518(0.84); C525(0.84)  LDD0595  [12]
 LDCM0279  AC2 HCT 116 C525(0.72); C287(0.72); C283(0.73); C518(0.78)  LDD0596  [12]
 LDCM0280  AC20 HCT 116 C518(0.89); C525(0.89); C609(0.90); C266(0.98)  LDD0597  [12]
 LDCM0281  AC21 HCT 116 C609(0.73); C266(0.75); C518(0.82); C525(0.82)  LDD0598  [12]
 LDCM0282  AC22 HCT 116 C266(0.92); C518(1.00); C525(1.00); C609(1.04)  LDD0599  [12]
 LDCM0283  AC23 HCT 116 C518(0.87); C525(0.87); C609(0.88); C178(0.94)  LDD0600  [12]
 LDCM0284  AC24 HCT 116 C266(0.91); C609(0.99); C518(1.08); C525(1.08)  LDD0601  [12]
 LDCM0285  AC25 HCT 116 C178(0.74); C283(0.75); C287(0.81); C266(0.84)  LDD0602  [12]
 LDCM0286  AC26 HCT 116 C178(0.58); C283(0.59); C287(0.60); C203(0.62)  LDD0603  [12]
 LDCM0287  AC27 HCT 116 C178(0.50); C266(0.61); C518(0.62); C525(0.62)  LDD0604  [12]
 LDCM0288  AC28 HCT 116 C178(0.47); C283(0.54); C287(0.56); C203(0.60)  LDD0605  [12]
 LDCM0289  AC29 HCT 116 C178(0.58); C518(0.62); C525(0.62); C287(0.63)  LDD0606  [12]
 LDCM0290  AC3 HCT 116 C287(0.66); C283(0.68); C525(0.76); C518(0.77)  LDD0607  [12]
 LDCM0291  AC30 HCT 116 C203(0.54); C518(0.60); C525(0.60); C266(0.61)  LDD0608  [12]
 LDCM0292  AC31 HCT 116 C178(0.44); C518(0.60); C525(0.60); C609(0.62)  LDD0609  [12]
 LDCM0293  AC32 HCT 116 C178(0.32); C203(0.46); C518(0.46); C525(0.46)  LDD0610  [12]
 LDCM0294  AC33 HCT 116 C178(0.42); C518(0.54); C525(0.54); C266(0.57)  LDD0611  [12]
 LDCM0295  AC34 HCT 116 C178(0.30); C266(0.49); C609(0.49); C203(0.52)  LDD0612  [12]
 LDCM0296  AC35 HCT 116 C266(1.33); C525(1.36); C203(1.44); C609(1.47)  LDD0613  [12]
 LDCM0297  AC36 HCT 116 C266(0.98); C525(1.21); C178(1.29); C518(1.30)  LDD0614  [12]
 LDCM0298  AC37 HCT 116 C266(1.04); C525(1.10); C283(1.16); C518(1.17)  LDD0615  [12]
 LDCM0299  AC38 HCT 116 C287(1.03); C266(1.04); C283(1.05); C525(1.09)  LDD0616  [12]
 LDCM0300  AC39 HCT 116 C283(0.84); C287(0.85); C525(1.01); C203(1.01)  LDD0617  [12]
 LDCM0301  AC4 HCT 116 C518(0.57); C525(0.75); C287(0.83); C203(0.87)  LDD0618  [12]
 LDCM0302  AC40 HCT 116 C266(0.96); C283(0.96); C609(0.97); C518(0.97)  LDD0619  [12]
 LDCM0303  AC41 HCT 116 C266(0.82); C283(0.94); C287(0.94); C525(0.97)  LDD0620  [12]
 LDCM0304  AC42 HCT 116 C178(0.95); C518(0.96); C525(0.98); C266(1.01)  LDD0621  [12]
 LDCM0305  AC43 HCT 116 C266(0.84); C283(0.85); C287(0.87); C518(1.03)  LDD0622  [12]
 LDCM0306  AC44 HCT 116 C266(0.89); C518(0.96); C283(0.99); C287(1.01)  LDD0623  [12]
 LDCM0307  AC45 HCT 116 C518(0.89); C525(0.91); C283(0.91); C266(0.92)  LDD0624  [12]
 LDCM0308  AC46 HCT 116 C283(0.62); C266(0.86); C287(0.88); C203(0.93)  LDD0625  [12]
 LDCM0309  AC47 HCT 116 C283(0.72); C266(0.77); C287(0.80); C178(0.87)  LDD0626  [12]
 LDCM0310  AC48 HCT 116 C283(0.77); C518(0.84); C287(0.86); C178(0.91)  LDD0627  [12]
 LDCM0311  AC49 HCT 116 C283(0.68); C266(0.69); C178(0.72); C203(0.77)  LDD0628  [12]
 LDCM0312  AC5 HCT 116 C518(0.55); C525(0.65); C287(0.81); C266(0.83)  LDD0629  [12]
 LDCM0313  AC50 HCT 116 C178(0.77); C266(0.79); C518(0.89); C203(0.89)  LDD0630  [12]
 LDCM0314  AC51 HCT 116 C283(1.01); C287(1.12); C203(1.20); C518(1.26)  LDD0631  [12]
 LDCM0315  AC52 HCT 116 C178(0.80); C283(0.82); C518(0.84); C287(0.86)  LDD0632  [12]
 LDCM0316  AC53 HCT 116 C178(0.75); C518(0.82); C266(0.82); C203(0.83)  LDD0633  [12]
 LDCM0317  AC54 HCT 116 C178(0.75); C266(0.76); C518(0.83); C203(0.89)  LDD0634  [12]
 LDCM0318  AC55 HCT 116 C266(0.82); C283(0.84); C178(0.88); C287(0.90)  LDD0635  [12]
 LDCM0319  AC56 HCT 116 C283(0.83); C178(0.84); C266(0.89); C203(0.90)  LDD0636  [12]
 LDCM0320  AC57 HCT 116 C266(0.61); C203(0.70); C283(0.85); C287(0.86)  LDD0637  [12]
 LDCM0321  AC58 HCT 116 C266(0.65); C203(0.80); C178(0.88); C518(1.03)  LDD0638  [12]
 LDCM0322  AC59 HCT 116 C178(0.55); C266(0.56); C203(0.59); C283(0.86)  LDD0639  [12]
 LDCM0323  AC6 HCT 116 C266(0.67); C203(0.70); C178(0.93); C609(0.93)  LDD0640  [12]
 LDCM0324  AC60 HCT 116 C178(0.54); C266(0.55); C203(0.61); C283(0.86)  LDD0641  [12]
 LDCM0325  AC61 HCT 116 C266(0.59); C203(0.76); C283(0.80); C518(0.80)  LDD0642  [12]
 LDCM0326  AC62 HCT 116 C266(0.58); C178(0.59); C203(0.67); C283(0.91)  LDD0643  [12]
 LDCM0327  AC63 HCT 116 C203(0.55); C178(0.60); C266(0.65); C287(0.91)  LDD0644  [12]
 LDCM0328  AC64 HCT 116 C266(0.58); C203(0.61); C178(0.66); C287(0.82)  LDD0645  [12]
 LDCM0329  AC65 HCT 116 C266(0.57); C178(0.61); C203(0.64); C283(0.68)  LDD0646  [12]
 LDCM0330  AC66 HCT 116 C266(0.62); C178(0.69); C518(0.74); C525(0.74)  LDD0647  [12]
 LDCM0331  AC67 HCT 116 C266(0.55); C203(0.56); C178(0.56); C287(0.77)  LDD0648  [12]
 LDCM0332  AC68 HCT 116 C609(0.71); C266(0.79); C203(0.95); C287(0.96)  LDD0649  [12]
 LDCM0333  AC69 HCT 116 C609(0.64); C266(0.72); C287(0.99); C203(1.00)  LDD0650  [12]
 LDCM0334  AC7 HCT 116 C203(0.73); C266(0.85); C287(0.97); C283(1.02)  LDD0651  [12]
 LDCM0335  AC70 HCT 116 C609(0.59); C266(0.62); C203(0.80); C283(0.90)  LDD0652  [12]
 LDCM0336  AC71 HCT 116 C266(0.92); C518(0.93); C525(0.93); C609(1.03)  LDD0653  [12]
 LDCM0337  AC72 HCT 116 C609(0.67); C266(0.70); C203(0.90); C283(0.95)  LDD0654  [12]
 LDCM0338  AC73 HCT 116 C609(0.72); C266(0.74); C518(0.93); C525(0.93)  LDD0655  [12]
 LDCM0339  AC74 HCT 116 C609(0.74); C266(0.83); C203(1.01); C518(1.11)  LDD0656  [12]
 LDCM0340  AC75 HCT 116 C609(0.80); C283(0.83); C266(0.87); C203(1.08)  LDD0657  [12]
 LDCM0341  AC76 HCT 116 C609(0.62); C266(0.76); C518(0.86); C525(0.86)  LDD0658  [12]
 LDCM0342  AC77 HCT 116 C609(0.63); C266(0.67); C518(0.76); C525(0.76)  LDD0659  [12]
 LDCM0343  AC78 HCT 116 C609(0.74); C266(0.79); C518(1.00); C525(1.00)  LDD0660  [12]
 LDCM0344  AC79 HCT 116 C609(0.74); C266(0.77); C518(0.92); C525(0.92)  LDD0661  [12]
 LDCM0345  AC8 HCT 116 C203(0.77); C266(0.77); C283(0.97); C609(0.97)  LDD0662  [12]
 LDCM0346  AC80 HCT 116 C609(0.62); C266(0.71); C287(0.96); C203(0.98)  LDD0663  [12]
 LDCM0347  AC81 HCT 116 C203(0.88); C609(0.92); C266(0.96); C287(1.01)  LDD0664  [12]
 LDCM0348  AC82 HCT 116 C609(0.87); C266(0.88); C203(1.00); C287(1.04)  LDD0665  [12]
 LDCM0349  AC83 HCT 116 C609(0.55); C518(0.60); C525(0.60); C266(0.61)  LDD0666  [12]
 LDCM0350  AC84 HCT 116 C178(0.51); C609(0.55); C518(0.61); C525(0.61)  LDD0667  [12]
 LDCM0351  AC85 HCT 116 C178(0.53); C266(0.66); C518(0.66); C525(0.66)  LDD0668  [12]
 LDCM0352  AC86 HCT 116 C178(0.66); C283(0.67); C518(0.74); C525(0.74)  LDD0669  [12]
 LDCM0353  AC87 HCT 116 C283(0.81); C178(0.89); C287(0.92); C609(0.92)  LDD0670  [12]
 LDCM0354  AC88 HCT 116 C609(0.71); C518(0.76); C525(0.76); C266(0.79)  LDD0671  [12]
 LDCM0355  AC89 HCT 116 C178(0.52); C609(0.52); C518(0.59); C525(0.59)  LDD0672  [12]
 LDCM0357  AC90 HCT 116 C283(0.63); C287(0.72); C178(0.99); C609(1.11)  LDD0674  [12]
 LDCM0358  AC91 HCT 116 C609(0.50); C178(0.53); C518(0.56); C525(0.56)  LDD0675  [12]
 LDCM0359  AC92 HCT 116 C609(0.48); C518(0.51); C525(0.51); C178(0.57)  LDD0676  [12]
 LDCM0360  AC93 HCT 116 C609(0.62); C178(0.64); C266(0.73); C518(0.73)  LDD0677  [12]
 LDCM0361  AC94 HCT 116 C609(0.70); C178(0.71); C266(0.79); C518(0.81)  LDD0678  [12]
 LDCM0362  AC95 HCT 116 C518(0.68); C525(0.68); C609(0.73); C283(0.76)  LDD0679  [12]
 LDCM0363  AC96 HCT 116 C609(0.53); C518(0.59); C525(0.59); C178(0.64)  LDD0680  [12]
 LDCM0364  AC97 HCT 116 C609(0.47); C518(0.53); C525(0.53); C283(0.53)  LDD0681  [12]
 LDCM0365  AC98 HCT 116 C266(0.62); C518(0.65); C525(0.65); C287(0.83)  LDD0682  [12]
 LDCM0366  AC99 HCT 116 C266(0.81); C518(0.94); C525(0.94); C287(0.96)  LDD0683  [12]
 LDCM0248  AKOS034007472 HCT 116 C178(1.33); C203(0.86); C266(1.13); C283(0.97)  LDD0565  [12]
 LDCM0356  AKOS034007680 HCT 116 C203(0.75); C283(0.83); C287(0.85); C266(0.89)  LDD0673  [12]
 LDCM0275  AKOS034007705 HCT 116 C266(0.60); C203(0.67); C609(0.92); C287(1.02)  LDD0592  [12]
 LDCM0020  ARS-1620 HCC44 C525(1.11)  LDD0078  [12]
 LDCM0102  BDHI 8 Jurkat C178(42.16); C266(17.75)  LDD0204  [31]
 LDCM0498  BS-3668 MDA-MB-231 C178(0.73)  LDD2091  [7]
 LDCM0108  Chloroacetamide HeLa C266(0.00); H89(0.00); C178(0.00); C518(0.00)  LDD0222  [23]
 LDCM0367  CL1 HCT 116 C266(0.99); C203(0.99); C518(1.38); C525(1.38)  LDD0684  [12]
 LDCM0368  CL10 HCT 116 C266(0.73); C203(0.76); C283(0.81); C518(0.82)  LDD0685  [12]
 LDCM0369  CL100 HCT 116 C518(0.53); C525(0.62); C283(0.74); C287(0.75)  LDD0686  [12]
 LDCM0370  CL101 HCT 116 C203(0.61); C266(0.69); C178(0.99); C609(1.10)  LDD0687  [12]
 LDCM0371  CL102 HCT 116 C203(0.82); C266(0.98); C178(1.29); C609(1.31)  LDD0688  [12]
 LDCM0372  CL103 HCT 116 C203(0.77); C266(0.91); C287(1.16); C283(1.21)  LDD0689  [12]
 LDCM0373  CL104 HCT 116 C203(0.73); C266(0.88); C609(1.17); C287(1.20)  LDD0690  [12]
 LDCM0374  CL105 HCT 116 C518(0.63); C525(0.63); C609(0.66); C266(0.77)  LDD0691  [12]
 LDCM0375  CL106 HCT 116 C609(0.48); C518(0.52); C525(0.52); C266(0.74)  LDD0692  [12]
 LDCM0376  CL107 HCT 116 C609(0.51); C518(0.54); C525(0.54); C266(0.63)  LDD0693  [12]
 LDCM0377  CL108 HCT 116 C609(0.48); C266(0.55); C518(0.58); C525(0.58)  LDD0694  [12]
 LDCM0378  CL109 HCT 116 C518(0.63); C525(0.63); C609(0.71); C266(0.73)  LDD0695  [12]
 LDCM0379  CL11 HCT 116 C283(0.83); C203(0.84); C287(0.88); C518(0.89)  LDD0696  [12]
 LDCM0380  CL110 HCT 116 C518(0.53); C525(0.53); C609(0.55); C266(0.67)  LDD0697  [12]
 LDCM0381  CL111 HCT 116 C518(0.66); C525(0.66); C266(0.71); C609(0.75)  LDD0698  [12]
 LDCM0382  CL112 HCT 116 C178(0.73); C518(0.86); C525(0.86); C266(0.87)  LDD0699  [12]
 LDCM0383  CL113 HCT 116 C178(0.37); C203(0.49); C518(0.54); C525(0.54)  LDD0700  [12]
 LDCM0384  CL114 HCT 116 C178(0.52); C266(0.61); C203(0.69); C518(0.70)  LDD0701  [12]
 LDCM0385  CL115 HCT 116 C178(0.58); C518(0.63); C525(0.63); C266(0.65)  LDD0702  [12]
 LDCM0386  CL116 HCT 116 C178(0.61); C203(0.65); C266(0.69); C518(0.71)  LDD0703  [12]
 LDCM0387  CL117 HCT 116 C203(1.04); C283(1.06); C609(1.08); C287(1.13)  LDD0704  [12]
 LDCM0388  CL118 HCT 116 C287(0.78); C283(0.79); C266(0.91); C518(0.91)  LDD0705  [12]
 LDCM0389  CL119 HCT 116 C287(0.78); C283(0.78); C266(0.80); C518(0.92)  LDD0706  [12]
 LDCM0390  CL12 HCT 116 C283(0.79); C287(0.83); C203(0.84); C266(0.84)  LDD0707  [12]
 LDCM0391  CL120 HCT 116 C283(0.77); C287(0.78); C266(0.94); C525(0.96)  LDD0708  [12]
 LDCM0392  CL121 HCT 116 C287(0.55); C266(0.77); C283(0.78); C203(0.80)  LDD0709  [12]
 LDCM0393  CL122 HCT 116 C266(0.76); C518(0.86); C178(0.87); C203(0.89)  LDD0710  [12]
 LDCM0394  CL123 HCT 116 C178(0.62); C518(0.76); C266(0.77); C203(0.82)  LDD0711  [12]
 LDCM0395  CL124 HCT 116 C283(0.59); C178(0.71); C266(0.74); C203(0.78)  LDD0712  [12]
 LDCM0396  CL125 HCT 116 C178(0.73); C518(0.77); C525(0.77); C203(0.92)  LDD0713  [12]
 LDCM0397  CL126 HCT 116 C266(0.73); C178(0.75); C203(0.77); C518(0.85)  LDD0714  [12]
 LDCM0398  CL127 HCT 116 C178(0.54); C266(0.68); C518(0.78); C525(0.78)  LDD0715  [12]
 LDCM0399  CL128 HCT 116 C266(0.57); C203(0.76); C287(0.83); C178(0.84)  LDD0716  [12]
 LDCM0400  CL13 HCT 116 C266(0.78); C283(0.90); C518(0.90); C525(0.90)  LDD0717  [12]
 LDCM0401  CL14 HCT 116 C266(0.88); C203(0.94); C283(0.96); C518(0.97)  LDD0718  [12]
 LDCM0402  CL15 HCT 116 C266(0.92); C518(0.95); C525(0.95); C203(1.01)  LDD0719  [12]
 LDCM0403  CL16 HCT 116 C266(0.62); C283(0.68); C287(0.70); C518(0.80)  LDD0720  [12]
 LDCM0404  CL17 HCT 116 C287(0.65); C266(0.73); C178(0.75); C609(0.78)  LDD0721  [12]
 LDCM0405  CL18 HCT 116 C266(0.52); C609(0.63); C287(0.74); C178(0.79)  LDD0722  [12]
 LDCM0406  CL19 HCT 116 C266(0.62); C609(0.70); C203(0.74); C287(0.80)  LDD0723  [12]
 LDCM0407  CL2 HCT 116 C203(1.04); C266(1.29); C518(1.31); C525(1.31)  LDD0724  [12]
 LDCM0408  CL20 HCT 116 C266(0.47); C609(0.55); C178(0.61); C287(0.64)  LDD0725  [12]
 LDCM0409  CL21 HCT 116 C266(0.51); C609(0.52); C178(0.56); C287(0.70)  LDD0726  [12]
 LDCM0410  CL22 HCT 116 C266(0.52); C178(0.69); C609(0.70); C203(0.95)  LDD0727  [12]
 LDCM0411  CL23 HCT 116 C266(0.61); C609(0.64); C287(0.74); C178(0.80)  LDD0728  [12]
 LDCM0412  CL24 HCT 116 C266(0.55); C609(0.58); C287(0.64); C283(0.67)  LDD0729  [12]
 LDCM0413  CL25 HCT 116 C178(0.70); C203(0.76); C266(0.54); C283(0.68)  LDD0730  [12]
 LDCM0414  CL26 HCT 116 C178(0.63); C203(0.86); C266(0.61); C283(0.75)  LDD0731  [12]
 LDCM0415  CL27 HCT 116 C178(0.66); C203(0.92); C266(0.51); C283(0.75)  LDD0732  [12]
 LDCM0416  CL28 HCT 116 C178(0.58); C203(0.74); C266(0.52); C283(0.53)  LDD0733  [12]
 LDCM0417  CL29 HCT 116 C178(0.64); C203(0.70); C266(0.57); C283(0.67)  LDD0734  [12]
 LDCM0418  CL3 HCT 116 C203(1.00); C266(1.01); C283(1.07); C287(1.11)  LDD0735  [12]
 LDCM0419  CL30 HCT 116 C178(0.93); C203(0.89); C266(0.65); C283(1.18)  LDD0736  [12]
 LDCM0420  CL31 HCT 116 C178(0.89); C203(0.88); C266(0.71); C283(1.01)  LDD0737  [12]
 LDCM0421  CL32 HCT 116 C178(0.78); C203(0.73); C266(0.60); C283(0.70)  LDD0738  [12]
 LDCM0422  CL33 HCT 116 C178(0.79); C203(0.61); C266(0.56); C283(0.74)  LDD0739  [12]
 LDCM0423  CL34 HCT 116 C178(0.61); C203(0.63); C266(0.48); C283(0.84)  LDD0740  [12]
 LDCM0424  CL35 HCT 116 C178(0.70); C203(0.87); C266(0.50); C283(0.77)  LDD0741  [12]
 LDCM0425  CL36 HCT 116 C178(0.66); C203(0.66); C266(0.52); C283(1.27)  LDD0742  [12]
 LDCM0426  CL37 HCT 116 C178(0.77); C203(0.69); C266(0.62); C283(0.98)  LDD0743  [12]
 LDCM0428  CL39 HCT 116 C178(0.69); C203(0.71); C266(0.53); C283(0.83)  LDD0745  [12]
 LDCM0429  CL4 HCT 116 C203(0.97); C266(0.88); C283(1.12); C287(1.13)  LDD0746  [12]
 LDCM0430  CL40 HCT 116 C178(0.68); C203(0.68); C266(0.55); C283(0.88)  LDD0747  [12]
 LDCM0431  CL41 HCT 116 C178(0.69); C203(0.77); C266(0.56); C283(1.14)  LDD0748  [12]
 LDCM0432  CL42 HCT 116 C178(0.68); C203(0.75); C266(0.64); C283(1.60)  LDD0749  [12]
 LDCM0433  CL43 HCT 116 C178(0.73); C203(0.66); C266(0.61); C283(0.75)  LDD0750  [12]
 LDCM0434  CL44 HCT 116 C178(0.77); C203(0.76); C266(0.55); C283(0.70)  LDD0751  [12]
 LDCM0435  CL45 HCT 116 C178(0.71); C203(0.64); C266(0.53); C283(0.66)  LDD0752  [12]
 LDCM0436  CL46 HCT 116 C178(0.82); C203(1.31); C266(1.62); C283(0.81)  LDD0753  [12]
 LDCM0437  CL47 HCT 116 C178(0.80); C203(1.17); C266(1.53); C283(0.91)  LDD0754  [12]
 LDCM0438  CL48 HCT 116 C178(0.93); C203(1.47); C266(1.61); C283(0.95)  LDD0755  [12]
 LDCM0439  CL49 HCT 116 C178(1.21); C203(1.07); C266(1.19); C283(0.80)  LDD0756  [12]
 LDCM0440  CL5 HCT 116 C203(0.92); C266(0.90); C283(1.00); C287(1.06)  LDD0757  [12]
 LDCM0441  CL50 HCT 116 C178(0.86); C203(1.25); C266(1.38); C283(0.98)  LDD0758  [12]
 LDCM0442  CL51 HCT 116 C178(0.83); C203(1.27); C266(1.46); C283(0.82)  LDD0759  [12]
 LDCM0443  CL52 HCT 116 C178(0.78); C203(1.32); C266(1.46); C283(0.83)  LDD0760  [12]
 LDCM0444  CL53 HCT 116 C178(0.79); C203(1.26); C266(1.46); C283(1.86)  LDD0761  [12]
 LDCM0445  CL54 HCT 116 C178(0.85); C203(1.17); C266(1.65); C283(1.12)  LDD0762  [12]
 LDCM0446  CL55 HCT 116 C178(1.00); C203(1.36); C266(1.61); C283(1.12)  LDD0763  [12]
 LDCM0447  CL56 HCT 116 C178(0.72); C203(1.10); C266(1.20); C283(1.21)  LDD0764  [12]
 LDCM0448  CL57 HCT 116 C178(0.75); C203(1.15); C266(1.38); C283(1.16)  LDD0765  [12]
 LDCM0449  CL58 HCT 116 C178(0.94); C203(1.43); C266(1.54); C283(0.79)  LDD0766  [12]
 LDCM0450  CL59 HCT 116 C178(0.92); C203(1.19); C266(1.20); C283(0.99)  LDD0767  [12]
 LDCM0451  CL6 HCT 116 C203(0.78); C266(0.89); C283(0.77); C287(0.79)  LDD0768  [12]
 LDCM0452  CL60 HCT 116 C178(1.00); C203(1.01); C266(1.20); C283(0.78)  LDD0769  [12]
 LDCM0453  CL61 HCT 116 C178(0.88); C203(0.85); C266(0.78); C283(0.86)  LDD0770  [12]
 LDCM0454  CL62 HCT 116 C178(0.78); C203(0.78); C266(0.76); C283(0.85)  LDD0771  [12]
 LDCM0455  CL63 HCT 116 C178(0.78); C203(0.69); C266(0.69); C283(1.16)  LDD0772  [12]
 LDCM0456  CL64 HCT 116 C178(0.66); C203(0.58); C266(0.60); C283(0.88)  LDD0773  [12]
 LDCM0457  CL65 HCT 116 C178(0.85); C203(0.89); C266(0.76); C283(1.25)  LDD0774  [12]
 LDCM0458  CL66 HCT 116 C178(0.74); C203(0.60); C266(0.57); C283(0.95)  LDD0775  [12]
 LDCM0459  CL67 HCT 116 C178(0.75); C203(0.63); C266(0.61); C283(1.44)  LDD0776  [12]
 LDCM0460  CL68 HCT 116 C178(0.62); C203(0.69); C266(0.58); C283(1.81)  LDD0777  [12]
 LDCM0461  CL69 HCT 116 C178(0.81); C203(0.63); C266(0.66); C283(0.88)  LDD0778  [12]
 LDCM0462  CL7 HCT 116 C203(0.90); C266(0.78); C283(0.72); C287(0.80)  LDD0779  [12]
 LDCM0463  CL70 HCT 116 C178(0.72); C203(0.75); C266(0.58); C283(0.94)  LDD0780  [12]
 LDCM0464  CL71 HCT 116 C178(0.70); C203(0.65); C266(0.62); C283(1.08)  LDD0781  [12]
 LDCM0465  CL72 HCT 116 C178(1.02); C203(0.79); C266(0.83); C283(0.89)  LDD0782  [12]
 LDCM0466  CL73 HCT 116 C178(0.72); C203(0.67); C266(0.63); C283(1.15)  LDD0783  [12]
 LDCM0467  CL74 HCT 116 C178(0.78); C203(0.73); C266(0.62); C283(1.32)  LDD0784  [12]
 LDCM0469  CL76 HCT 116 C203(0.87); C266(0.84); C283(1.89); C287(1.27)  LDD0786  [12]
 LDCM0470  CL77 HCT 116 C203(0.92); C266(0.87); C283(2.31); C287(1.64)  LDD0787  [12]
 LDCM0471  CL78 HCT 116 C203(0.97); C266(0.90); C283(1.35); C287(1.04)  LDD0788  [12]
 LDCM0472  CL79 HCT 116 C203(0.86); C266(0.76); C283(1.45); C287(1.04)  LDD0789  [12]
 LDCM0473  CL8 HCT 116 C203(0.84); C266(0.76); C283(1.00); C287(1.00)  LDD0790  [12]
 LDCM0474  CL80 HCT 116 C203(0.99); C266(0.87); C283(1.20); C287(1.04)  LDD0791  [12]
 LDCM0475  CL81 HCT 116 C203(0.89); C266(0.81); C283(1.29); C287(1.00)  LDD0792  [12]
 LDCM0476  CL82 HCT 116 C203(1.00); C266(0.82); C283(1.60); C287(1.20)  LDD0793  [12]
 LDCM0477  CL83 HCT 116 C203(0.82); C266(0.81); C283(1.53); C287(1.16)  LDD0794  [12]
 LDCM0478  CL84 HCT 116 C203(0.87); C266(0.81); C283(1.28); C287(1.07)  LDD0795  [12]
 LDCM0479  CL85 HCT 116 C203(0.90); C266(0.79); C283(1.41); C287(1.15)  LDD0796  [12]
 LDCM0480  CL86 HCT 116 C203(0.92); C266(0.93); C283(1.54); C287(1.22)  LDD0797  [12]
 LDCM0481  CL87 HCT 116 C203(0.86); C266(0.82); C283(1.48); C287(1.17)  LDD0798  [12]
 LDCM0482  CL88 HCT 116 C203(1.02); C266(0.79); C283(2.10); C287(1.36)  LDD0799  [12]
 LDCM0483  CL89 HCT 116 C203(1.03); C266(0.79); C283(1.51); C287(1.14)  LDD0800  [12]
 LDCM0484  CL9 HCT 116 C203(0.78); C266(0.80); C283(0.86); C287(0.91)  LDD0801  [12]
 LDCM0485  CL90 HCT 116 C203(0.83); C266(0.92); C283(1.63); C287(1.34)  LDD0802  [12]
 LDCM0486  CL91 HCT 116 C178(1.06); C203(0.87); C266(0.86); C283(1.05)  LDD0803  [12]
 LDCM0487  CL92 HCT 116 C178(1.06); C203(0.85); C266(0.86); C283(1.19)  LDD0804  [12]
 LDCM0488  CL93 HCT 116 C178(1.26); C203(1.08); C266(0.96); C283(1.04)  LDD0805  [12]
 LDCM0489  CL94 HCT 116 C178(1.52); C203(0.81); C266(0.81); C283(1.06)  LDD0806  [12]
 LDCM0490  CL95 HCT 116 C178(1.27); C203(0.80); C266(0.91); C283(1.10)  LDD0807  [12]
 LDCM0491  CL96 HCT 116 C178(1.29); C203(0.84); C266(0.84); C283(0.92)  LDD0808  [12]
 LDCM0492  CL97 HCT 116 C178(1.07); C203(0.81); C266(0.74); C283(0.82)  LDD0809  [12]
 LDCM0493  CL98 HCT 116 C178(1.40); C203(0.80); C266(0.74); C283(0.66)  LDD0810  [12]
 LDCM0494  CL99 HCT 116 C178(1.77); C203(0.79); C266(0.81); C283(0.72)  LDD0811  [12]
 LDCM0495  E2913 HEK-293T C178(0.97); C609(0.97); C266(0.75); C203(1.10)  LDD1698  [32]
 LDCM0625  F8 Ramos C178(1.04); C203(0.64); C266(0.53)  LDD2187  [33]
 LDCM0572  Fragment10 Ramos C178(1.15); C203(1.04); C266(0.87)  LDD2189  [33]
 LDCM0573  Fragment11 Ramos C178(0.34); C203(0.09); C266(0.16); 0.81  LDD2190  [33]
 LDCM0574  Fragment12 Ramos C178(1.32); C203(1.63); C266(0.84)  LDD2191  [33]
 LDCM0575  Fragment13 Ramos C178(1.21); C203(0.84); C266(0.86)  LDD2192  [33]
 LDCM0576  Fragment14 Ramos C178(0.87); C203(1.32); C266(0.86); 2.81  LDD2193  [33]
 LDCM0579  Fragment20 Ramos C178(1.34); C203(3.10); C266(1.19)  LDD2194  [33]
 LDCM0580  Fragment21 Ramos C178(0.91); C203(0.81); C266(0.93)  LDD2195  [33]
 LDCM0582  Fragment23 Ramos C178(3.07); C203(1.97); C266(0.89)  LDD2196  [33]
 LDCM0578  Fragment27 Ramos C178(1.11); C203(1.01); C266(1.01)  LDD2197  [33]
 LDCM0586  Fragment28 Ramos C178(0.88); C203(1.55); C266(1.04)  LDD2198  [33]
 LDCM0588  Fragment30 Ramos C178(1.29); C203(0.74); C266(0.80)  LDD2199  [33]
 LDCM0589  Fragment31 Ramos C178(1.13); C203(1.36); C266(1.24)  LDD2200  [33]
 LDCM0590  Fragment32 Ramos C178(0.83); C203(1.01); C266(0.72)  LDD2201  [33]
 LDCM0468  Fragment33 HCT 116 C178(0.85); C203(0.68); C266(0.59); C283(0.94)  LDD0785  [12]
 LDCM0596  Fragment38 Ramos C178(1.07); C203(1.00); C266(0.85)  LDD2203  [33]
 LDCM0566  Fragment4 Ramos C178(1.11); C203(1.44); C266(0.87)  LDD2184  [33]
 LDCM0427  Fragment51 HCT 116 C178(0.53); C203(0.64); C266(0.53); C283(1.36)  LDD0744  [12]
 LDCM0610  Fragment52 Ramos C178(1.17); C203(0.84); C266(0.64)  LDD2204  [33]
 LDCM0614  Fragment56 Ramos C178(1.26); C203(0.70); C266(0.75)  LDD2205  [33]
 LDCM0569  Fragment7 Ramos C178(1.43); C203(0.94); C266(0.95)  LDD2186  [33]
 LDCM0571  Fragment9 Ramos C178(1.24); C203(5.19); C266(1.30)  LDD2188  [33]
 LDCM0116  HHS-0101 DM93 Y394(0.93); Y304(5.10); Y145(6.02)  LDD0264  [11]
 LDCM0117  HHS-0201 DM93 Y394(1.11); Y145(1.21); Y304(1.87)  LDD0265  [11]
 LDCM0118  HHS-0301 DM93 Y394(0.77); Y304(0.91); Y145(2.43)  LDD0266  [11]
 LDCM0119  HHS-0401 DM93 Y145(0.99); Y304(1.65); Y394(4.02)  LDD0267  [11]
 LDCM0120  HHS-0701 DM93 Y394(1.49); Y304(1.84); Y145(2.39)  LDD0268  [11]
 LDCM0015  HNE MDA-MB-231 0.75  LDD0346  [33]
 LDCM0107  IAA HeLa C266(0.00); H89(0.00); H306(0.00); C178(0.00)  LDD0221  [23]
 LDCM0124  JWB142 DM93 Y304(0.35)  LDD0286  [10]
 LDCM0126  JWB150 DM93 Y304(1.19)  LDD0288  [10]
 LDCM0127  JWB152 DM93 Y304(0.70)  LDD0289  [10]
 LDCM0129  JWB202 DM93 Y304(0.14)  LDD0291  [10]
 LDCM0130  JWB211 DM93 Y304(0.41)  LDD0292  [10]
 LDCM0022  KB02 HCT 116 C203(1.32)  LDD0080  [12]
 LDCM0023  KB03 HCT 116 C203(0.71)  LDD0081  [12]
 LDCM0024  KB05 HCT 116 C203(0.56)  LDD0082  [12]
 LDCM0109  NEM HeLa H89(0.00); H306(0.00)  LDD0223  [23]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C178(1.50)  LDD2093  [7]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C178(0.81)  LDD2098  [7]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C178(1.39)  LDD2099  [7]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C283(1.66)  LDD2105  [7]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C178(1.38)  LDD2107  [7]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C178(0.88)  LDD2109  [7]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C178(1.45); C287(0.55)  LDD2111  [7]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C178(0.67)  LDD2119  [7]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C178(1.22)  LDD2123  [7]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C178(1.05)  LDD2125  [7]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C178(1.07)  LDD2127  [7]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C178(0.84)  LDD2128  [7]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C178(1.97)  LDD2129  [7]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C178(2.20)  LDD2135  [7]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C178(1.58)  LDD2136  [7]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C178(1.12); C609(0.67)  LDD2137  [7]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C178(1.08)  LDD2140  [7]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C178(1.62)  LDD2144  [7]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C178(1.32)  LDD2146  [7]
 LDCM0627  NUDT7-COV-1 HEK-293T C283(2.31); C203(1.28); C178(1.17); C463(1.02)  LDD2206  [34]
 LDCM0628  OTUB2-COV-1 HEK-293T C178(1.40); C203(1.36); C266(0.80); C463(0.77)  LDD2207  [34]
 LDCM0014  Panhematin hPBMC 3.13  LDD0064  [9]
 LDCM0021  THZ1 HCT 116 C266(1.07)  LDD2173  [12]

The Interaction Atlas With This Target

The Drug(s) Related To This Target

Approved
Click To Hide/Show 3 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Glutamic Acid Small molecular drug DB00142
L-glutamine Small molecular drug DB00130
Esculin . DB13155

References

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Mass spectrometry data entry: PXD028270
5 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
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Mass spectrometry data entry: PXD039908 , PXD029761
8 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
9 A Chemical Proteomic Map of Heme-Protein Interactions. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12.
Mass spectrometry data entry: PXD034651
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Mass spectrometry data entry: PXD042377
14 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
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Mass spectrometry data entry: PXD028853
17 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
18 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
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Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD036569
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Mass spectrometry data entry: PXD039931
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Mass spectrometry data entry: PXD033004
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Mass spectrometry data entry: PXD041264
26 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010
27 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD044402
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Mass spectrometry data entry: PXD027578
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