Details of the Probe

General Information of Probe

Probe ID
LDPC0398
Probe Name
C158
Synonyms
Z3433406460
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 366.29
Lipid-water partition coefficient (xlogp) 2
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C16H13F3N4O3
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-6-oxo-4-(trifluoromethyl)-7H-furo[2,3-b]pyridine-2-carboxamide
Canonical SMILES
C#CCCC1(N=N1)CCNC(=O)C2=CC3=C(O2)NC(=O)C=C3C(F)(F)F
InChI
InChI=1S/C16H13F3N4O3/c1-2-3-4-15(22-23-15)5-6-20-13(25)11-7-9-10(16(17,18)19)8-12(24)21-14(9)26-11/h1,7-8H,3-6H2,(H,20,25)(H,21,24)
InChIKey
VDKWKCPDHRMLDB-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

143 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 8.94  LDD1838 
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) LDTP03611 9.51  LDD1838 
5'-nucleotidase domain-containing protein 2 (NT5DC2) LDTP18414 9.32  LDD1838 
Adenosine deaminase (ADA) LDTP01803 21.56  LDD1838 
Adenosine kinase (ADK) LDTP04689 12.30  LDD1838 
Adenylosuccinate synthetase isozyme 2 (ADSS2) LDTP03541 10.34  LDD1838 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 72.00  LDD1838 
ADP-dependent glucokinase (ADPGK) LDTP11127 12.91  LDD1838 
Alcohol dehydrogenase class-3 (ADH5) LDTP02587 30.27  LDD1838 
Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) LDTP03560 9.32  LDD1838 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 10.78  LDD1838 
All-trans-retinol 13,14-reductase (RETSAT) LDTP15097 11.88  LDD1838 
Alpha-1,2-mannosyltransferase ALG9 (ALG9) LDTP12002 9.19  LDD1838 
Antigen peptide transporter 1 (TAP1) LDTP05408 21.41  LDD1838 
Antigen peptide transporter 2 (TAP2) LDTP05409 9.71  LDD1838 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 22.32  LDD1838 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 15.89  LDD1838 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 9.71  LDD1838 
ATP-dependent DNA/RNA helicase DHX36 (DHX36) LDTP11841 15.03  LDD1838 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 10.34  LDD1838 
ATPase PAAT (PAAT) LDTP12057 9.92  LDD1838 
Atypical kinase COQ8A, mitochondrial (COQ8A) LDTP09285 17.39  LDD1838 
Bifunctional epoxide hydrolase 2 (EPHX2) LDTP03692 8.88  LDD1838 
Branched-chain alpha-ketoacid dehydrogenase kinase (BCKDK) LDTP00462 59.71  LDD1838 
Carboxylesterase 3 (CES3) LDTP07683 37.01  LDD1838 
Catechol O-methyltransferase (COMT) LDTP03145 10.48  LDD1838 
Ceramide synthase 1 (CERS1) LDTP03394 10.78  LDD1838 
Ceramide synthase 2 (CERS2) LDTP10329 15.78  LDD1838 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 9.06  LDD1838 
Complex I assembly factor ACAD9, mitochondrial (ACAD9) LDTP12048 11.08  LDD1838 
Corrinoid adenosyltransferase MMAB (MMAB) LDTP10286 12.55  LDD1838 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 22.16  LDD1838 
Cytochrome b5 type B (CYB5B) LDTP00697 23.92  LDD1838 
D-dopachrome decarboxylase (DDT) LDTP03513 30.70  LDD1838 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 9.51  LDD1838 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 9.51  LDD1838 
Dihydropteridine reductase (QDPR) LDTP02342 11.71  LDD1838 
DNA polymerase subunit gamma-1 (POLG) LDTP04596 11.63  LDD1838 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 9.19  LDD1838 
DNA-directed RNA polymerase, mitochondrial (POLRMT) LDTP00267 9.13  LDD1838 
DnaJ homolog subfamily C member 10 (DNAJC10) LDTP08590 8.94  LDD1838 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 10.56  LDD1838 
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) LDTP03170 58.49  LDD1838 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 36.50  LDD1838 
Endoplasmic reticulum aminopeptidase 2 (ERAP2) LDTP07503 13.36  LDD1838 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 13.36  LDD1838 
Enolase-phosphatase E1 (ENOPH1) LDTP13314 28.84  LDD1838 
Enoyl-CoA delta isomerase 1, mitochondrial (ECI1) LDTP03965 18.51  LDD1838 
Enoyl-CoA delta isomerase 2 (ECI2) LDTP01245 9.06  LDD1838 
Epimerase family protein SDR39U1 (SDR39U1) LDTP16070 11.00  LDD1838 
Epoxide hydrolase 1 (EPHX1) LDTP02175 9.58  LDD1838 
ERO1-like protein beta (ERO1B) LDTP08393 13.09  LDD1838 
FAST kinase domain-containing protein 1, mitochondrial (FASTKD1) LDTP06919 9.51  LDD1838 
Fatty acid CoA ligase Acsl3 (ACSL3) LDTP01634 9.45  LDD1838 
Ferrochelatase, mitochondrial (FECH) LDTP03198 19.56  LDD1838 
Fumarylacetoacetase (FAH) LDTP02868 20.82  LDD1838 
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) LDTP06721 9.00  LDD1838 
Geranylgeranyl transferase type-2 subunit alpha (RABGGTA) LDTP09845 10.27  LDD1838 
Geranylgeranyl transferase type-2 subunit beta (RABGGTB) LDTP04569 31.12  LDD1838 
Glutaminase kidney isoform, mitochondrial (GLS) LDTP01465 11.08  LDD1838 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 9.58  LDD1838 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 9.78  LDD1838 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 32.67  LDD1838 
Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2) LDTP04032 12.30  LDD1838 
GTP-binding protein Rheb (RHEB) LDTP06371 13.83  LDD1838 
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) LDTP13352 14.72  LDD1838 
Haloacid dehalogenase-like hydrolase domain-containing protein 3 (HDHD3) LDTP15879 11.31  LDD1838 
Heme oxygenase 1 (HMOX1) LDTP02359 14.22  LDD1838 
Heme oxygenase 2 (HMOX2) LDTP03540 15.56  LDD1838 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 15.14  LDD1838 
Isochorismatase domain-containing protein 2 (ISOC2) LDTP18123 10.56  LDD1838 
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (IDH3B) LDTP00885 22.78  LDD1838 
Isoleucine--tRNA ligase, mitochondrial (IARS2) LDTP12588 9.45  LDD1838 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 11.47  LDD1838 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 15.56  LDD1838 
Long-chain-fatty-acid--CoA ligase 4 (ACSL4) LDTP00982 16.45  LDD1838 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 9.06  LDD1838 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 25.28  LDD1838 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 9.99  LDD1838 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 9.13  LDD1838 
Malonate--CoA ligase ACSF3, mitochondrial (ACSF3) LDTP06848 9.32  LDD1838 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 12.55  LDD1838 
Methylmalonyl-CoA mutase, mitochondrial (MMUT) LDTP03150 9.06  LDD1838 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 10.34  LDD1838 
Mitochondrial ribonuclease P catalytic subunit (PRORP) LDTP00536 15.45  LDD1838 
Mitogen-activated protein kinase 14 (MAPK14) LDTP06547 9.51  LDD1838 
Multidrug resistance-associated protein 1 (ABCC1) LDTP03671 13.93  LDD1838 
NAD(+) hydrolase SARM1 (SARM1) LDTP07640 10.78  LDD1838 
NADH dehydrogenase 1 alpha subcomplex subunit 6 (NDUFA6) LDTP04746 8.88  LDD1838 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 9.99  LDD1838 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 12.38  LDD1838 
Neurolysin, mitochondrial (NLN) LDTP11494 12.13  LDD1838 
Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial (EARS2) LDTP06997 9.32  LDD1838 
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (CPOX) LDTP03813 16.00  LDD1838 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 64.00  LDD1838 
Patatin-like phospholipase domain-containing protein 6 (PNPLA6) LDTP08617 11.88  LDD1838 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 25.81  LDD1838 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 18.13  LDD1838 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 13.18  LDD1838 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 38.85  LDD1838 
Peroxisomal multifunctional enzyme type 2 (HSD17B4) LDTP04440 11.96  LDD1838 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 10.06  LDD1838 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 15.35  LDD1838 
Presequence protease, mitochondrial (PITRM1) LDTP07003 14.03  LDD1838 
Probable arginine--tRNA ligase, mitochondrial (RARS2) LDTP07092 10.27  LDD1838 
Probable ATP-dependent RNA helicase DDX28 (DDX28) LDTP12633 10.63  LDD1838 
Probable glutathione peroxidase 8 (GPX8) LDTP09495 10.93  LDD1838 
Probable methyltransferase TARBP1 (TARBP1) LDTP05850 8.88  LDD1838 
Prolyl 3-hydroxylase 1 (P3H1) LDTP06750 11.16  LDD1838 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 9.99  LDD1838 
Prostaglandin reductase 3 (PTGR3) LDTP15422 10.27  LDD1838 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 24.93  LDD1838 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 11.71  LDD1838 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 9.65  LDD1838 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 11.55  LDD1838 
Protein arginine methyltransferase NDUFAF7, mitochondrial (NDUFAF7) LDTP07961 9.92  LDD1838 
Protein disulfide-isomerase A5 (PDIA5) LDTP06145 9.38  LDD1838 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 9.00  LDD1838 
Protein NDRG2 (NDRG2) LDTP13638 16.45  LDD1838 
Protein O-mannosyl-transferase TMTC3 (TMTC3) LDTP07868 32.90  LDD1838 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 17.27  LDD1838 
Protoporphyrinogen oxidase (PPOX) LDTP04353 12.38  LDD1838 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 13.93  LDD1838 
Receptor-type tyrosine-protein phosphatase F (PTPRF) LDTP02499 11.71  LDD1838 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 12.73  LDD1838 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 46.85  LDD1838 
Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 9.13  LDD1838 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 16.11  LDD1838 
Sentrin-specific protease 8 (SENP8) LDTP10547 15.24  LDD1838 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 17.15  LDD1838 
sn-1-specific diacylglycerol lipase ABHD11 (ABHD11) LDTP09225 26.72  LDD1838 
Squalene synthase (FDFT1) LDTP03842 20.39  LDD1838 
Sterol O-acyltransferase 1 (SOAT1) LDTP03769 9.85  LDD1838 
Sulfide:quinone oxidoreductase, mitochondrial (SQOR) LDTP14278 8.94  LDD1838 
Thiopurine S-methyltransferase (TPMT) LDTP04428 9.25  LDD1838 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 13.09  LDD1838 
Threonine--tRNA ligase, mitochondrial (TARS2) LDTP11319 9.32  LDD1838 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 13.83  LDD1838 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 32.90  LDD1838 
tRNA methyltransferase 10 homolog C (TRMT10C) LDTP07937 9.00  LDD1838 
UDP-glucose:glycoprotein glucosyltransferase 2 (UGGT2) LDTP12850 11.31  LDD1838 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 10.48  LDD1838 
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (PDK1) LDTP06320 12.04  LDD1838 
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⏷ Show the Full List of 143 Enzyme
60 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Amino acid transporter heavy chain SLC3A2 (SLC3A2) LDTP02256 9.25  LDD1838 
Amyloid-beta precursor protein (APP) LDTP02071 10.34  LDD1838 
Anion exchange protein 2 (SLC4A2) LDTP02061 11.39  LDD1838 
Anoctamin-6 (ANO6) LDTP06855 9.71  LDD1838 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 11.63  LDD1838 
B-cell receptor-associated protein 29 (BCAP29) LDTP16201 11.71  LDD1838 
B-cell receptor-associated protein 31 (BCAP31) LDTP04426 9.06  LDD1838 
Calcium uptake protein 2, mitochondrial (MICU2) LDTP08673 9.65  LDD1838 
Coiled-coil domain-containing protein 22 (CCDC22) LDTP01056 10.63  LDD1838 
Cystine/glutamate transporter (SLC7A11) LDTP13734 11.71  LDD1838 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 8.94  LDD1838 
Disks large homolog 1 (DLG1) LDTP05706 9.06  LDD1838 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 9.25  LDD1838 
Equilibrative nucleoside transporter 1 (SLC29A1) LDTP10985 11.88  LDD1838 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 13.55  LDD1838 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 24.08  LDD1838 
Erlin-1 (ERLIN1) LDTP01234 10.06  LDD1838 
Erlin-2 (ERLIN2) LDTP01455 9.58  LDD1838 
Importin-4 (IPO4) LDTP09515 23.59  LDD1838 
Integrin beta-1 (ITGB1) LDTP02122 16.22  LDD1838 
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) LDTP01100 19.16  LDD1838 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 9.19  LDD1838 
Major facilitator superfamily domain-containing protein 10 (MFSD10) LDTP06198 44.94  LDD1838 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 10.34  LDD1838 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 9.45  LDD1838 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 11.55  LDD1838 
Metaxin-1 (MTX1) LDTP05900 9.25  LDD1838 
Metaxin-2 (MTX2) LDTP01217 15.24  LDD1838 
Metaxin-3 (MTX3) LDTP14970 22.47  LDD1838 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 23.10  LDD1838 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 11.16  LDD1838 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 12.47  LDD1838 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 11.39  LDD1838 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 17.88  LDD1838 
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 10.34  LDD1838 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 9.00  LDD1838 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 13.09  LDD1838 
Mitoguardin 1 (MIGA1) LDTP09028 11.31  LDD1838 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 11.88  LDD1838 
Mpv17-like protein 2 (MPV17L2) LDTP14952 18.38  LDD1838 
Neuropilin-1 (NRP1) LDTP00433 15.24  LDD1838 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 13.27  LDD1838 
Peroxisomal membrane protein PMP34 (SLC25A17) LDTP00872 11.47  LDD1838 
Protein GPR107 (GPR107) LDTP07236 14.22  LDD1838 
Protein GPR108 (GPR108) LDTP12383 18.64  LDD1838 
Protein Mpv17 (MPV17) LDTP03869 14.62  LDD1838 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 17.03  LDD1838 
Slit homolog 2 protein (SLIT2) LDTP01427 15.24  LDD1838 
Sodium bicarbonate cotransporter 3 (SLC4A7) LDTP14275 10.13  LDD1838 
Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) LDTP02544 11.55  LDD1838 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 9.78  LDD1838 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 12.64  LDD1838 
Solute carrier family 25 member 35 (SLC25A35) LDTP17106 58.49  LDD1838 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 13.55  LDD1838 
SUN domain-containing protein 2 (SUN2) LDTP13256 9.45  LDD1838 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 14.72  LDD1838 
Transmembrane protein 126A (TMEM126A) LDTP15948 13.83  LDD1838 
Transmembrane protein 201 (TMEM201) LDTP07058 11.16  LDD1838 
Transmembrane protein 205 (TMEM205) LDTP07667 26.17  LDD1838 
Transmembrane protein 59 (TMEM59) LDTP11406 10.63  LDD1838 
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⏷ Show the Full List of 60 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
TSC22 domain family protein 3 (TSC22D3) LDTP10904 9.38  LDD1838 
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6 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 10.13  LDD1838 
CD166 antigen (ALCAM) LDTP05973 20.68  LDD1838 
Cell adhesion molecule 1 (CADM1) LDTP11441 13.27  LDD1838 
HLA class I histocompatibility antigen, A alpha chain (HLA-A) LDTP02040 10.78  LDD1838 
HLA class I histocompatibility antigen, C alpha chain (HLA-C) LDTP02491 13.64  LDD1838 
Neural cell adhesion molecule 1 (NCAM1) LDTP02666 12.30  LDD1838 
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⏷ Show the Full List of 6 Immunoglobulin
81 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
A-kinase anchor protein 8 (AKAP8) LDTP00880 9.19  LDD1838 
Alpha-2-macroglobulin receptor-associated protein (LRPAP1) LDTP03545 11.39  LDD1838 
Alpha-actinin-4 (ACTN4) LDTP00843 14.42  LDD1838 
AP-3 complex subunit sigma-1 (AP3S1) LDTP09804 16.91  LDD1838 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 11.08  LDD1838 
Cadherin-2 (CDH2) LDTP02977 9.85  LDD1838 
cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) LDTP02697 9.25  LDD1838 
CD109 antigen (CD109) LDTP07760 18.00  LDD1838 
Centrin-2 (CETN2) LDTP03926 10.06  LDD1838 
Clustered mitochondria protein homolog (CLUH) LDTP14486 14.62  LDD1838 
Coiled-coil domain-containing protein 134 (CCDC134) LDTP11979 11.96  LDD1838 
Coiled-coil domain-containing protein 6 (CCDC6) LDTP06515 9.45  LDD1838 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 9.71  LDD1838 
DnaJ homolog subfamily C member 16 (DNAJC16) LDTP13863 10.06  LDD1838 
DnaJ homolog subfamily C member 3 (DNAJC3) LDTP05789 8.88  LDD1838 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 17.03  LDD1838 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 11.00  LDD1838 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 10.27  LDD1838 
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (ECSIT) LDTP11065 9.38  LDD1838 
G-rich sequence factor 1 (GRSF1) LDTP05668 8.88  LDD1838 
Ganglioside-induced differentiation-associated protein 1 (GDAP1) LDTP09324 10.93  LDD1838 
Guanine nucleotide-binding protein subunit beta-like protein 1 (GNB1L) LDTP18337 21.86  LDD1838 
HAUS augmin-like complex subunit 3 (HAUS3) LDTP07318 10.70  LDD1838 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 9.71  LDD1838 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 9.06  LDD1838 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 12.91  LDD1838 
Heme-binding protein 1 (HEBP1) LDTP16078 12.30  LDD1838 
Hepatoma-derived growth factor-related protein 2 (HDGFL2) LDTP08081 9.65  LDD1838 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 9.25  LDD1838 
Homer protein homolog 1 (HOMER1) LDTP08407 9.13  LDD1838 
Immunoglobulin-binding protein 1 (IGBP1) LDTP05089 13.83  LDD1838 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 11.31  LDD1838 
Integrin alpha-2 (ITGA2) LDTP02893 9.45  LDD1838 
Interferon-induced protein with tetratricopeptide repeats 5 (IFIT5) LDTP05828 11.00  LDD1838 
Kelch-like ECH-associated protein 1 (KEAP1) LDTP06051 16.68  LDD1838 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 16.56  LDD1838 
Kinesin light chain 1 (KLC1) LDTP05533 9.58  LDD1838 
Kinetochore protein Nuf2 (NUF2) LDTP11525 8.94  LDD1838 
Kinetochore protein Spc24 (SPC24) LDTP09069 41.93  LDD1838 
Large ribosomal subunit protein bL12m (MRPL12) LDTP04537 8.88  LDD1838 
Large ribosomal subunit protein mL40 (MRPL40) LDTP12395 9.19  LDD1838 
Large ribosomal subunit protein mL46 (MRPL46) LDTP15976 16.22  LDD1838 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 13.74  LDD1838 
MICOS complex subunit MIC19 (CHCHD3) LDTP12764 9.51  LDD1838 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 9.78  LDD1838 
Mitotic spindle assembly checkpoint protein MAD1 (MAD1L1) LDTP14239 8.88  LDD1838 
NADH dehydrogenase 1 alpha subcomplex assembly factor 2 (NDUFAF2) LDTP08761 9.65  LDD1838 
Nestin (NES) LDTP04206 8.94  LDD1838 
Neuferricin (CYB5D2) LDTP15623 19.43  LDD1838 
Neurofilament light polypeptide (NEFL) LDTP02180 13.64  LDD1838 
Neurofilament medium polypeptide (NEFM) LDTP02181 9.78  LDD1838 
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (NFU1) LDTP13622 9.92  LDD1838 
Nuclear receptor coactivator 5 (NCOA5) LDTP12230 9.85  LDD1838 
Nucleobindin-1 (NUCB1) LDTP05375 12.55  LDD1838 
Nucleobindin-2 (NUCB2) LDTP05160 11.55  LDD1838 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 9.51  LDD1838 
Pentatricopeptide repeat-containing protein 1, mitochondrial (PTCD1) LDTP01130 9.92  LDD1838 
Prefoldin subunit 6 (PFDN6) LDTP00573 9.99  LDD1838 
Prelamin-A/C (LMNA) LDTP01932 10.78  LDD1838 
Protein bicaudal D homolog 2 (BICD2) LDTP09410 9.92  LDD1838 
Protein CEBPZOS (CEBPZOS) LDTP18883 9.58  LDD1838 
Protein Hook homolog 2 (HOOK2) LDTP10255 9.13  LDD1838 
Protein SERAC1 (SERAC1) LDTP10487 9.99  LDD1838 
Protein unc-119 homolog B (UNC119B) LDTP00105 9.51  LDD1838 
RAB11-binding protein RELCH (RELCH) LDTP16172 9.00  LDD1838 
Reticulocalbin-2 (RCN2) LDTP06097 9.45  LDD1838 
Reticulon-2 (RTN2) LDTP01167 9.38  LDD1838 
Reticulon-3 (RTN3) LDTP01522 9.51  LDD1838 
Small ribosomal subunit protein mS31 (MRPS31) LDTP09836 10.34  LDD1838 
Small ribosomal subunit protein mS39 (PTCD3) LDTP10285 9.38  LDD1838 
Syntaxin-18 (STX18) LDTP13086 10.06  LDD1838 
T-complex protein 1 subunit beta (CCT2) LDTP05113 14.03  LDD1838 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 10.70  LDD1838 
Tetratricopeptide repeat protein 39C (TTC39C) LDTP17713 11.47  LDD1838 
TIP41-like protein (TIPRL) LDTP01285 10.70  LDD1838 
TraB domain-containing protein (TRABD) LDTP19963 11.16  LDD1838 
Trophoblast glycoprotein (TPBG) LDTP05960 12.38  LDD1838 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 8.88  LDD1838 
UL16-binding protein 3 (ULBP3) LDTP11552 54.19  LDD1838 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 9.19  LDD1838 
Vimentin (VIM) LDTP02297 12.30  LDD1838 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1838 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587