Details of the Target
General Information of Target
| Target ID | LDTP17106 | |||||
|---|---|---|---|---|---|---|
| Target Name | Solute carrier family 25 member 35 (SLC25A35) | |||||
| Gene Name | SLC25A35 | |||||
| Gene ID | 399512 | |||||
| Synonyms |
Solute carrier family 25 member 35 |
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| 3D Structure | ||||||
| Sequence |
MASEQDVRARLQRAGQEHLLRFWAELAPEPRAALLAELALLEPEALREHCRRAAEACARP
HGPPPDLAARLRPLPPERVGRASRSDPETRRRWEEEGFRQISLNKVAVLLLAGGQGTRLG VTYPKGMYRVGLPSRKTLYQLQAERIRRVEQLAGERHGTRCTVPWYVMTSEFTLGPTAEF FREHNFFHLDPANVVMFEQRLLPAVTFDGKVILERKDKVAMAPDGNGGLYCALEDHKILE DMERRGVEFVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDG VPQVVEYSEISPETAQLRASDGSLLYNAGNICNHFFTRGFLKAVTREFEPLLKPHVAVKK VPYVDEEGNLVKPLKPNGIKMEKFVFDVFRFAKNFAALEVLREEEFSPLKNAEPADRDSP RTARQALLTQHYRWALRAGARFLDAHGAWLPELPSLPPNGDPPAICEISPLVSYSGEGLE VYLQGREFQSPLILDEDQAREPQLQES |
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| Target Bioclass |
Transporter and channel
|
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| Family |
Mitochondrial carrier (TC 2.A.29) family
|
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| Subcellular location |
Mitochondrion inner membrane
|
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| Function | Putative antiporter that exchanges dicarboxylates and sulfur oxoanions across the inner membrane of mitochondria. | |||||
| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Target Site Mutations in Different Cell Lines
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
JW-RF-010 Probe Info |
 |
N.A. | LDD0026 | [1] | |
|
TFBX Probe Info |
 |
N.A. | LDD0027 | [1] | |
|
AOyne Probe Info |
 |
10.90 | LDD0443 | [2] | |
PAL-AfBPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
C156 Probe Info |
 |
7.26 | LDD1836 | [3] | |
|
C158 Probe Info |
 |
58.49 | LDD1838 | [3] | |
|
C159 Probe Info |
 |
9.19 | LDD1839 | [3] | |
|
C160 Probe Info |
 |
10.78 | LDD1840 | [3] | |
|
C161 Probe Info |
 |
24.59 | LDD1841 | [3] | |
References