Details of the Probe

General Information of Probe

Probe ID
LDPC0400
Probe Name
C160
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 357.429
Lipid-water partition coefficient (xlogp) 3.6438
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C20H24FN3O2
Canonical SMILES
[H]C#CC([H])([H])C([H])([H])C1(C([H])([H])C([H])([H])C(=O)N([H])C2(C([H])(O[H])c3c([H])c([H])c(F)c([H])c3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N=N1
InChI
InChI=1S/C20H24FN3O2/c1-2-3-13-20(23-24-20)14-10-17(25)22-19(11-4-5-12-19)18(26)15-6-8-16(21)9-7-15/h1,6-9,18,26H,3-5,10-14H2,(H,22,25)/t18-/m1/s1
InChIKey
LELDLUMNFHBPNO-GOSISDBHSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

141 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 8.94  LDD1840 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 12.04  LDD1840 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 12.82  LDD1840 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 9.38  LDD1840 
5'-nucleotidase domain-containing protein 1 (NT5DC1) LDTP17247 7.21  LDD1840 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 10.41  LDD1840 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 6.92  LDD1840 
Acid ceramidase (ASAH1) LDTP05905 8.82  LDD1840 
ADP-dependent glucokinase (ADPGK) LDTP11127 18.51  LDD1840 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 9.92  LDD1840 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 11.79  LDD1840 
Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) LDTP03560 6.96  LDD1840 
All-trans-retinol 13,14-reductase (RETSAT) LDTP15097 8.11  LDD1840 
Alpha-galactosidase A (GLA) LDTP02141 7.57  LDD1840 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 9.32  LDD1840 
Anaphase-promoting complex subunit 7 (ANAPC7) LDTP13409 8.75  LDD1840 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 9.85  LDD1840 
ATP-dependent RNA helicase DDX51 (DDX51) LDTP15453 7.31  LDD1840 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 8.69  LDD1840 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 9.51  LDD1840 
Beta-galactosidase (GLB1) LDTP02837 7.89  LDD1840 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 7.06  LDD1840 
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPSS1) LDTP00717 9.51  LDD1840 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 13.36  LDD1840 
Branched-chain alpha-ketoacid dehydrogenase kinase (BCKDK) LDTP00462 7.57  LDD1840 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 27.10  LDD1840 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 12.82  LDD1840 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 18.64  LDD1840 
Catechol O-methyltransferase (COMT) LDTP03145 6.87  LDD1840 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 8.00  LDD1840 
Ceramide glucosyltransferase (UGCG) LDTP06617 8.06  LDD1840 
Ceramide kinase (CERK) LDTP09391 23.43  LDD1840 
Ceramide synthase 1 (CERS1) LDTP03394 16.00  LDD1840 
Ceramide synthase 2 (CERS2) LDTP10329 20.11  LDD1840 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 7.84  LDD1840 
Choline kinase alpha (CHKA) LDTP03787 10.13  LDD1840 
Choline/ethanolaminephosphotransferase 1 (CEPT1) LDTP14264 9.06  LDD1840 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 7.67  LDD1840 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 24.93  LDD1840 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 20.97  LDD1840 
Cytochrome b5 type B (CYB5B) LDTP00697 56.10  LDD1840 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 15.24  LDD1840 
Cytosolic purine 5'-nucleotidase (NT5C2) LDTP04327 35.02  LDD1840 
DCN1-like protein 4 (DCUN1D4) LDTP09799 12.73  LDD1840 
DCN1-like protein 5 (DCUN1D5) LDTP11199 7.84  LDD1840 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 11.79  LDD1840 
Delta(24)-sterol reductase (DHCR24) LDTP06375 17.39  LDD1840 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 7.41  LDD1840 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 7.52  LDD1840 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 12.04  LDD1840 
Dihydrofolate reductase (DHFR) LDTP01769 22.78  LDD1840 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 9.58  LDD1840 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 11.39  LDD1840 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 8.28  LDD1840 
E3 ubiquitin-protein ligase RNF13 (RNF13) LDTP00804 9.00  LDD1840 
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETFDH) LDTP06511 22.47  LDD1840 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 7.84  LDD1840 
Endoplasmic reticulum aminopeptidase 2 (ERAP2) LDTP07503 9.78  LDD1840 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 7.11  LDD1840 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 11.71  LDD1840 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 15.24  LDD1840 
Epoxide hydrolase 1 (EPHX1) LDTP02175 19.70  LDD1840 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 11.63  LDD1840 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 12.04  LDD1840 
Heme oxygenase 1 (HMOX1) LDTP02359 19.70  LDD1840 
Heme oxygenase 2 (HMOX2) LDTP03540 25.28  LDD1840 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 9.06  LDD1840 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 17.03  LDD1840 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 11.88  LDD1840 
Isochorismatase domain-containing protein 1 (ISOC1) LDTP19851 7.26  LDD1840 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 8.06  LDD1840 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 15.78  LDD1840 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 17.63  LDD1840 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 8.46  LDD1840 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 8.40  LDD1840 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 7.46  LDD1840 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 8.57  LDD1840 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 19.16  LDD1840 
Lysosomal acid phosphatase (ACP2) LDTP02539 8.06  LDD1840 
Lysosomal alpha-glucosidase (GAA) LDTP02486 8.00  LDD1840 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 16.45  LDD1840 
Lysosomal protective protein (CTSA) LDTP02505 20.39  LDD1840 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 11.47  LDD1840 
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (MAN1A2) LDTP00975 8.46  LDD1840 
Metalloendopeptidase OMA1, mitochondrial (OMA1) LDTP10249 11.63  LDD1840 
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial (ALDH6A1) LDTP05346 35.02  LDD1840 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 22.16  LDD1840 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 23.43  LDD1840 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 7.67  LDD1840 
N-alpha-acetyltransferase 40 (NAA40) LDTP08265 6.92  LDD1840 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 8.75  LDD1840 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 9.65  LDD1840 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 25.46  LDD1840 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 10.56  LDD1840 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 22.47  LDD1840 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 10.20  LDD1840 
Obg-like ATPase 1 (OLA1) LDTP12610 43.71  LDD1840 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 21.41  LDD1840 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 8.88  LDD1840 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 27.47  LDD1840 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 25.11  LDD1840 
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) LDTP01562 7.52  LDD1840 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 6.92  LDD1840 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 7.67  LDD1840 
Phenylalanine--tRNA ligase beta subunit (FARSB) LDTP12586 6.87  LDD1840 
Phospholipase A2 group XV (PLA2G15) LDTP09088 16.00  LDD1840 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 9.71  LDD1840 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 9.45  LDD1840 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 55.33  LDD1840 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 16.11  LDD1840 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 14.42  LDD1840 
Prolyl endopeptidase-like (PREPL) LDTP06849 12.82  LDD1840 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 9.25  LDD1840 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 27.47  LDD1840 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 11.00  LDD1840 
Protein O-GlcNAcase (OGA) LDTP00988 10.27  LDD1840 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 12.55  LDD1840 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 9.19  LDD1840 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 10.93  LDD1840 
Ras-related protein Rab-24 (RAB24) LDTP10020 7.16  LDD1840 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 16.00  LDD1840 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 19.43  LDD1840 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 9.85  LDD1840 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 7.26  LDD1840 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 6.87  LDD1840 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 11.88  LDD1840 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 13.45  LDD1840 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 11.63  LDD1840 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 9.71  LDD1840 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 9.58  LDD1840 
Squalene synthase (FDFT1) LDTP03842 11.08  LDD1840 
Sulfide:quinone oxidoreductase, mitochondrial (SQOR) LDTP14278 8.00  LDD1840 
TLC domain-containing protein 1 (TLCD1) LDTP10182 54.19  LDD1840 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 12.30  LDD1840 
Triokinase/FMN cyclase (TKFC) LDTP06779 13.45  LDD1840 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 13.74  LDD1840 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 10.48  LDD1840 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 8.22  LDD1840 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 8.69  LDD1840 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 19.56  LDD1840 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 10.70  LDD1840 
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⏷ Show the Full List of 141 Enzyme
103 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 7.01  LDD1840 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 14.52  LDD1840 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 7.67  LDD1840 
Amino acid transporter heavy chain SLC3A2 (SLC3A2) LDTP02256 20.97  LDD1840 
Amyloid-beta precursor protein (APP) LDTP02071 17.88  LDD1840 
Anoctamin-6 (ANO6) LDTP06855 6.96  LDD1840 
AP-1 complex subunit mu-1 (AP1M1) LDTP11407 12.91  LDD1840 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 7.46  LDD1840 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 22.63  LDD1840 
BRI3-binding protein (BRI3BP) LDTP15648 7.21  LDD1840 
Calcium uptake protein 2, mitochondrial (MICU2) LDTP08673 9.19  LDD1840 
Cell division cycle protein 20 homolog (CDC20) LDTP05662 13.00  LDD1840 
Ceramide transfer protein (CERT1) LDTP14140 22.63  LDD1840 
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16) LDTP16163 14.62  LDD1840 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 7.01  LDD1840 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 40.50  LDD1840 
Derlin-1 (DERL1) LDTP11245 13.83  LDD1840 
Disks large homolog 1 (DLG1) LDTP05706 11.47  LDD1840 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 64.00  LDD1840 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 12.21  LDD1840 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 9.25  LDD1840 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 8.00  LDD1840 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 7.06  LDD1840 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 8.88  LDD1840 
Integral membrane protein 2B (ITM2B) LDTP13833 13.00  LDD1840 
Integral membrane protein 2C (ITM2C) LDTP12451 9.51  LDD1840 
Intraflagellar transport protein 56 (IFT56) LDTP00010 6.87  LDD1840 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 10.13  LDD1840 
Lysosome membrane protein 2 (SCARB2) LDTP06034 18.90  LDD1840 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 7.67  LDD1840 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 8.06  LDD1840 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 9.92  LDD1840 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 10.06  LDD1840 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 8.00  LDD1840 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 19.56  LDD1840 
Metal cation symporter ZIP14 (SLC39A14) LDTP06293 13.09  LDD1840 
Metaxin-1 (MTX1) LDTP05900 15.45  LDD1840 
Metaxin-2 (MTX2) LDTP01217 10.56  LDD1840 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 7.52  LDD1840 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 9.71  LDD1840 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 7.36  LDD1840 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 7.52  LDD1840 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 17.75  LDD1840 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 11.00  LDD1840 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD1840 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD1840 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 11.31  LDD1840 
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 6.96  LDD1840 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 15.24  LDD1840 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 18.77  LDD1840 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 39.67  LDD1840 
Mitoguardin 1 (MIGA1) LDTP09028 16.91  LDD1840 
Mpv17-like protein 2 (MPV17L2) LDTP14952 20.53  LDD1840 
Nucleoporin NDC1 (NDC1) LDTP11213 12.30  LDD1840 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 8.28  LDD1840 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 17.39  LDD1840 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 7.36  LDD1840 
Prosaposin (PSAP) LDTP02215 15.03  LDD1840 
Protein FAM8A1 (FAM8A1) LDTP16190 9.45  LDD1840 
Protein GPR107 (GPR107) LDTP07236 33.36  LDD1840 
Protein GPR108 (GPR108) LDTP12383 19.29  LDD1840 
Protein SEC13 homolog (SEC13) LDTP04707 9.65  LDD1840 
Protein spinster homolog 1 (SPNS1) LDTP11844 11.16  LDD1840 
Protein tweety homolog 3 (TTYH3) LDTP11615 30.70  LDD1840 
Protein wntless homolog (WLS) LDTP07156 10.48  LDD1840 
Proton-coupled amino acid transporter 1 (SLC36A1) LDTP08016 13.09  LDD1840 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 9.38  LDD1840 
Proton-coupled zinc antiporter SLC30A9, mitochondrial (SLC30A9) LDTP07610 7.06  LDD1840 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 11.55  LDD1840 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 11.55  LDD1840 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 21.11  LDD1840 
Sideroflexin-4 (SFXN4) LDTP07531 17.88  LDD1840 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 22.32  LDD1840 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 51.27  LDD1840 
Sodium bicarbonate cotransporter 3 (SLC4A7) LDTP14275 7.89  LDD1840 
Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) LDTP02544 7.36  LDD1840 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 18.64  LDD1840 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 9.32  LDD1840 
Solute carrier family 25 member 35 (SLC25A35) LDTP17106 10.78  LDD1840 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 9.92  LDD1840 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 13.64  LDD1840 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 14.83  LDD1840 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 18.13  LDD1840 
Sugar transporter SWEET1 (SLC50A1) LDTP11136 21.71  LDD1840 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 6.87  LDD1840 
Tetraspanin-3 (TSPAN3) LDTP16813 29.24  LDD1840 
Transferrin receptor protein 1 (TFRC) LDTP01969 8.75  LDD1840 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 23.10  LDD1840 
Translocator protein (TSPO) LDTP03546 7.31  LDD1840 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 26.35  LDD1840 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 15.14  LDD1840 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 8.34  LDD1840 
Transmembrane protein 126A (TMEM126A) LDTP15948 43.11  LDD1840 
Transmembrane protein 199 (TMEM199) LDTP08881 26.17  LDD1840 
Transmembrane protein 230 (TMEM230) LDTP10065 10.20  LDD1840 
Transmembrane protein 245 (TMEM245) LDTP15979 10.70  LDD1840 
Transmembrane protein 33 (TMEM33) LDTP04787 8.00  LDD1840 
Transmembrane protein 59 (TMEM59) LDTP11406 26.17  LDD1840 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 7.26  LDD1840 
Vang-like protein 1 (VANGL1) LDTP09288 7.62  LDD1840 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 49.18  LDD1840 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 38.59  LDD1840 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 9.06  LDD1840 
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⏷ Show the Full List of 103 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 8.17  LDD1840 
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2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 6.96  LDD1840 
Cell adhesion molecule 1 (CADM1) LDTP11441 7.57  LDD1840 
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94 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 7.01  LDD1840 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 9.65  LDD1840 
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (ACAP2) LDTP06302 9.85  LDD1840 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 7.84  LDD1840 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 26.91  LDD1840 
BRCA1-associated ATM activator 1 (BRAT1) LDTP07598 7.31  LDD1840 
Caprin-1 (CAPRIN1) LDTP06121 25.99  LDD1840 
Centrin-2 (CETN2) LDTP03926 7.11  LDD1840 
Centromere protein K (CENPK) LDTP11143 12.82  LDD1840 
Clustered mitochondria protein homolog (CLUH) LDTP14486 21.11  LDD1840 
Collectin-12 (COLEC12) LDTP07031 6.96  LDD1840 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 6.96  LDD1840 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 25.11  LDD1840 
Cytoplasmic dynein 2 intermediate chain 2 (DYNC2I2) LDTP10281 9.25  LDD1840 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 11.55  LDD1840 
Dynactin subunit 3 (DCTN3) LDTP01359 7.26  LDD1840 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 13.36  LDD1840 
EF-hand domain-containing protein D2 (EFHD2) LDTP15701 8.82  LDD1840 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 31.34  LDD1840 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 99.73  LDD1840 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 8.51  LDD1840 
Ganglioside GM2 activator (GM2A) LDTP02927 7.73  LDD1840 
General transcription factor IIH subunit 4 (GTF2H4) LDTP09861 7.21  LDD1840 
Golgi apparatus protein 1 (GLG1) LDTP09920 7.01  LDD1840 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 19.97  LDD1840 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 8.06  LDD1840 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 8.22  LDD1840 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 8.00  LDD1840 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 7.26  LDD1840 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 7.31  LDD1840 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 22.78  LDD1840 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 7.01  LDD1840 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 9.13  LDD1840 
Kinetochore protein Spc24 (SPC24) LDTP09069 10.63  LDD1840 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 9.71  LDD1840 
Large proline-rich protein BAG6 (BAG6) LDTP04094 12.38  LDD1840 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 7.57  LDD1840 
MAGUK p55 subfamily member 2 (MPP2) LDTP06068 7.11  LDD1840 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 29.65  LDD1840 
MAU2 chromatid cohesion factor homolog (MAU2) LDTP14304 8.63  LDD1840 
Mediator of RNA polymerase II transcription subunit 25 (MED25) LDTP07906 6.87  LDD1840 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 9.65  LDD1840 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 24.93  LDD1840 
Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) LDTP14126 7.62  LDD1840 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 68.59  LDD1840 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 23.92  LDD1840 
Neuferricin (CYB5D2) LDTP15623 7.46  LDD1840 
Neurofilament medium polypeptide (NEFM) LDTP02181 7.73  LDD1840 
Nuclear inhibitor of protein phosphatase 1 (PPP1R8) LDTP05711 10.13  LDD1840 
Nucleobindin-1 (NUCB1) LDTP05375 41.36  LDD1840 
Nucleobindin-2 (NUCB2) LDTP05160 36.50  LDD1840 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 9.19  LDD1840 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 8.06  LDD1840 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 8.22  LDD1840 
Optic atrophy 3 protein (OPA3) LDTP16006 11.47  LDD1840 
p53 and DNA damage-regulated protein 1 (PDRG1) LDTP16099 38.05  LDD1840 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 10.48  LDD1840 
Protein CEBPZOS (CEBPZOS) LDTP18883 26.72  LDD1840 
Protein FAM114A2 (FAM114A2) LDTP16080 10.93  LDD1840 
Protein FAM162A (FAM162A) LDTP10056 10.20  LDD1840 
Protein jagunal homolog 1 (JAGN1) LDTP08904 13.18  LDD1840 
Protein kish-B (TMEM167B) LDTP12545 9.51  LDD1840 
Protein LYRIC (MTDH) LDTP08224 11.39  LDD1840 
Protein SET (SET) LDTP05277 10.70  LDD1840 
Protein unc-119 homolog A (UNC119) LDTP05868 18.38  LDD1840 
Protein unc-119 homolog B (UNC119B) LDTP00105 20.97  LDD1840 
Protein UXT (UXT) LDTP13125 7.67  LDD1840 
Protein YIF1A (YIF1A) LDTP01494 9.25  LDD1840 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 14.42  LDD1840 
RAD50-interacting protein 1 (RINT1) LDTP07476 9.00  LDD1840 
Reticulocalbin-2 (RCN2) LDTP06097 9.38  LDD1840 
Reticulon-2 (RTN2) LDTP01167 7.52  LDD1840 
Reticulon-3 (RTN3) LDTP01522 19.97  LDD1840 
Reticulon-4 (RTN4) LDTP12412 19.43  LDD1840 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 11.63  LDD1840 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 9.85  LDD1840 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 6.87  LDD1840 
Synaptic vesicle glycoprotein 2A (SV2A) LDTP07934 9.78  LDD1840 
Synaptogyrin-2 (SYNGR2) LDTP00859 13.83  LDD1840 
Syntaxin-10 (STX10) LDTP00986 24.42  LDD1840 
Syntaxin-18 (STX18) LDTP13086 14.72  LDD1840 
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) LDTP14263 16.56  LDD1840 
TBC1 domain family member 23 (TBC1D23) LDTP12651 7.06  LDD1840 
Tetraspanin-6 (TSPAN6) LDTP14458 29.86  LDD1840 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 11.24  LDD1840 
Tetratricopeptide repeat protein 39C (TTC39C) LDTP17713 8.57  LDD1840 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 9.58  LDD1840 
TraB domain-containing protein (TRABD) LDTP19963 9.45  LDD1840 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 11.71  LDD1840 
Transmembrane protein 209 (TMEM209) LDTP18272 7.41  LDD1840 
Tubulin beta-4A chain (TUBB4A) LDTP02037 7.52  LDD1840 
Tubulin beta-6 chain (TUBB6) LDTP11233 6.87  LDD1840 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 32.45  LDD1840 
Uncharacterized protein KIAA2013 (KIAA2013) LDTP17652 6.87  LDD1840 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1840 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587