Details of the Target

General Information of Target

Target ID LDTP10188
Target Name FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1)
Gene Name FOXRED1
Gene ID 55572
Synonyms
FAD-dependent oxidoreductase domain-containing protein 1; EC 1.-.-.-
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPKKFQGENTKSAAARARRAEAKAAADAKKQKELEDAYWKDDDKHVMRKEQRKEEKEKRR
LDQLERKKETQRLLEEEDSKLKGGKAPRVATSSKVTRAQIEDTLRRDHQLREAPDTAEKA
KSHLEVPLEENVNRRVLEEGSVEARTIEDAIAVLSVAEEAADRHPERRMRAAFTAFEEAQ
LPRLKQENPNMRLSQLKQLLKKEWLRSPDNPMNQRAVPFNAPK
Target Bioclass
Enzyme
Subcellular location
Mitochondrion inner membrane
Function Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Involved in mid-late stages of complex I assembly.
Uniprot ID
Q96CU9
Ensemble ID
ENST00000263578.10
HGNC ID
HGNC:26927

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HT1197 SNV: p.E399Q DBIA    Probe Info 
Ishikawa (Heraklio) 02 ER SNV: p.A408V DBIA    Probe Info 
NALM6 SNV: p.A445T .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 12 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		12.53  LDD0402  [1]
Jackson_1
 Probe Info  		20.00  LDD0122  [2]
YN-1
 Probe Info  		100.00  LDD0444  [3]
STPyne
 Probe Info  		K42(10.00)  LDD0277  [4]
HPAP
 Probe Info  		3.27  LDD0062  [5]
IPM
 Probe Info  		C239(3.10)  LDD1701  [6]
DBIA
 Probe Info  		C239(1.19)  LDD0532  [7]
4-Iodoacetamidophenylacetylene
 Probe Info  		C239(0.00); C331(0.00)  LDD0038  [8]
IA-alkyne
 Probe Info  		C331(0.00); C239(0.00)  LDD0036  [8]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [8]
TFBX
 Probe Info  		N.A.  LDD0027  [9]
AOyne
 Probe Info  		15.00  LDD0443  [10]
PAL-AfBPP Probe
Click To Hide/Show 117 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C004
 Probe Info  		5.58  LDD1714  [11]
C011
 Probe Info  		7.41  LDD1720  [11]
C018
 Probe Info  		7.78  LDD1726  [11]
C022
 Probe Info  		19.56  LDD1728  [11]
C026
 Probe Info  		5.13  LDD1732  [11]
C041
 Probe Info  		13.83  LDD1741  [11]
C044
 Probe Info  		12.55  LDD1743  [11]
C055
 Probe Info  		32.67  LDD1752  [11]
C059
 Probe Info  		5.74  LDD1756  [11]
C060
 Probe Info  		6.73  LDD1757  [11]
C068
 Probe Info  		15.24  LDD1764  [11]
C070
 Probe Info  		23.59  LDD1766  [11]
C071
 Probe Info  		9.00  LDD1767  [11]
C082
 Probe Info  		10.70  LDD1774  [11]
C085
 Probe Info  		8.11  LDD1777  [11]
C087
 Probe Info  		8.51  LDD1779  [11]
C092
 Probe Info  		16.80  LDD1783  [11]
C106
 Probe Info  		44.94  LDD1793  [11]
C107
 Probe Info  		15.45  LDD1794  [11]
C108
 Probe Info  		36.25  LDD1795  [11]
C129
 Probe Info  		5.46  LDD1811  [11]
C130
 Probe Info  		8.82  LDD1812  [11]
C133
 Probe Info  		11.16  LDD1815  [11]
C134
 Probe Info  		30.06  LDD1816  [11]
C135
 Probe Info  		20.11  LDD1817  [11]
C139
 Probe Info  		15.14  LDD1821  [11]
C140
 Probe Info  		11.00  LDD1822  [11]
C141
 Probe Info  		11.31  LDD1823  [11]
C143
 Probe Info  		19.70  LDD1825  [11]
C153
 Probe Info  		32.22  LDD1834  [11]
C156
 Probe Info  		6.02  LDD1836  [11]
C159
 Probe Info  		19.70  LDD1839  [11]
C160
 Probe Info  		11.63  LDD1840  [11]
C161
 Probe Info  		19.56  LDD1841  [11]
C167
 Probe Info  		5.35  LDD1847  [11]
C169
 Probe Info  		31.56  LDD1849  [11]
C178
 Probe Info  		41.93  LDD1857  [11]
C185
 Probe Info  		5.13  LDD1863  [11]
C193
 Probe Info  		7.06  LDD1869  [11]
C194
 Probe Info  		13.36  LDD1870  [11]
C195
 Probe Info  		6.54  LDD1871  [11]
C196
 Probe Info  		14.52  LDD1872  [11]
C198
 Probe Info  		20.82  LDD1874  [11]
C201
 Probe Info  		38.05  LDD1877  [11]
C215
 Probe Info  		5.46  LDD1889  [11]
C216
 Probe Info  		17.27  LDD1890  [11]
C218
 Probe Info  		10.78  LDD1892  [11]
C219
 Probe Info  		6.96  LDD1893  [11]
C220
 Probe Info  		20.97  LDD1894  [11]
C222
 Probe Info  		6.59  LDD1896  [11]
C225
 Probe Info  		7.84  LDD1898  [11]
C226
 Probe Info  		9.92  LDD1899  [11]
C228
 Probe Info  		14.93  LDD1901  [11]
C229
 Probe Info  		7.36  LDD1902  [11]
C231
 Probe Info  		23.75  LDD1904  [11]
C233
 Probe Info  		23.75  LDD1906  [11]
C243
 Probe Info  		28.05  LDD1916  [11]
C252
 Probe Info  		25.46  LDD1925  [11]
C255
 Probe Info  		6.11  LDD1928  [11]
C264
 Probe Info  		42.22  LDD1935  [11]
C265
 Probe Info  		30.27  LDD1936  [11]
C266
 Probe Info  		8.63  LDD1937  [11]
C269
 Probe Info  		5.90  LDD1939  [11]
C277
 Probe Info  		23.92  LDD1947  [11]
C280
 Probe Info  		36.25  LDD1950  [11]
C286
 Probe Info  		5.70  LDD1956  [11]
C287
 Probe Info  		10.06  LDD1957  [11]
C288
 Probe Info  		9.51  LDD1958  [11]
C289
 Probe Info  		25.63  LDD1959  [11]
C290
 Probe Info  		6.77  LDD1960  [11]
C293
 Probe Info  		34.06  LDD1963  [11]
C296
 Probe Info  		30.91  LDD1966  [11]
C299
 Probe Info  		7.36  LDD1968  [11]
C305
 Probe Info  		10.93  LDD1974  [11]
C313
 Probe Info  		34.54  LDD1980  [11]
C314
 Probe Info  		12.13  LDD1981  [11]
C320
 Probe Info  		9.65  LDD1986  [11]
C343
 Probe Info  		17.15  LDD2005  [11]
C344
 Probe Info  		4.92  LDD2006  [11]
C347
 Probe Info  		6.63  LDD2008  [11]
C348
 Probe Info  		10.93  LDD2009  [11]
C349
 Probe Info  		41.64  LDD2010  [11]
C350
 Probe Info  		36.00  LDD2011  [11]
C353
 Probe Info  		6.11  LDD2014  [11]
C354
 Probe Info  		11.71  LDD2015  [11]
C355
 Probe Info  		61.82  LDD2016  [11]
C356
 Probe Info  		16.00  LDD2017  [11]
C357
 Probe Info  		8.06  LDD2018  [11]
C362
 Probe Info  		42.52  LDD2023  [11]
C363
 Probe Info  		21.26  LDD2024  [11]
C367
 Probe Info  		5.66  LDD2028  [11]
C378
 Probe Info  		8.69  LDD2037  [11]
C380
 Probe Info  		5.90  LDD2039  [11]
C382
 Probe Info  		8.94  LDD2041  [11]
C386
 Probe Info  		11.79  LDD2045  [11]
C387
 Probe Info  		5.13  LDD2046  [11]
C388
 Probe Info  		45.89  LDD2047  [11]
C390
 Probe Info  		96.34  LDD2049  [11]
C391
 Probe Info  		15.89  LDD2050  [11]
C393
 Probe Info  		7.26  LDD2052  [11]
C399
 Probe Info  		12.82  LDD2058  [11]
C400
 Probe Info  		8.40  LDD2059  [11]
C405
 Probe Info  		6.77  LDD2063  [11]
C424
 Probe Info  		7.89  LDD2079  [11]
C428
 Probe Info  		19.43  LDD2083  [11]
C429
 Probe Info  		12.21  LDD2084  [11]
C431
 Probe Info  		20.39  LDD2086  [11]
C433
 Probe Info  		10.70  LDD2088  [11]
FFF probe11
 Probe Info  		20.00  LDD0471  [12]
FFF probe13
 Probe Info  		20.00  LDD0475  [12]
FFF probe14
 Probe Info  		20.00  LDD0477  [12]
FFF probe2
 Probe Info  		20.00  LDD0463  [12]
FFF probe3
 Probe Info  		20.00  LDD0464  [12]
FFF probe6
 Probe Info  		15.32  LDD0467  [12]
JN0003
 Probe Info  		20.00  LDD0469  [12]
VE-P
 Probe Info  		N.A.  LDD0396  [13]
OEA-DA
 Probe Info  		20.00  LDD0046  [14]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0026  4SU-RNA+native RNA HEK-293T C222(20.00)  LDD0372  [15]
 LDCM0214  AC1 HEK-293T C331(1.05); C116(1.57)  LDD1507  [16]
 LDCM0215  AC10 HCT 116 C239(1.19)  LDD0532  [7]
 LDCM0216  AC100 HCT 116 C239(0.88)  LDD0533  [7]
 LDCM0217  AC101 HCT 116 C239(0.84)  LDD0534  [7]
 LDCM0218  AC102 HCT 116 C239(0.98)  LDD0535  [7]
 LDCM0219  AC103 HCT 116 C239(0.89)  LDD0536  [7]
 LDCM0220  AC104 HCT 116 C239(0.87)  LDD0537  [7]
 LDCM0221  AC105 HCT 116 C239(0.90)  LDD0538  [7]
 LDCM0222  AC106 HCT 116 C239(0.99)  LDD0539  [7]
 LDCM0223  AC107 HCT 116 C239(1.03)  LDD0540  [7]
 LDCM0224  AC108 HCT 116 C239(0.74)  LDD0541  [7]
 LDCM0225  AC109 HCT 116 C239(0.79)  LDD0542  [7]
 LDCM0226  AC11 HCT 116 C239(1.04)  LDD0543  [7]
 LDCM0227  AC110 HCT 116 C239(0.86)  LDD0544  [7]
 LDCM0228  AC111 HCT 116 C239(0.82)  LDD0545  [7]
 LDCM0229  AC112 HCT 116 C239(0.98)  LDD0546  [7]
 LDCM0230  AC113 HCT 116 C239(0.91)  LDD0547  [7]
 LDCM0231  AC114 HCT 116 C239(0.98)  LDD0548  [7]
 LDCM0232  AC115 HCT 116 C239(0.99)  LDD0549  [7]
 LDCM0233  AC116 HCT 116 C239(1.06)  LDD0550  [7]
 LDCM0234  AC117 HCT 116 C239(1.16)  LDD0551  [7]
 LDCM0235  AC118 HCT 116 C239(1.06)  LDD0552  [7]
 LDCM0236  AC119 HCT 116 C239(1.04)  LDD0553  [7]
 LDCM0237  AC12 HCT 116 C239(1.23)  LDD0554  [7]
 LDCM0238  AC120 HCT 116 C239(0.95)  LDD0555  [7]
 LDCM0239  AC121 HCT 116 C239(1.17)  LDD0556  [7]
 LDCM0240  AC122 HCT 116 C239(1.02)  LDD0557  [7]
 LDCM0241  AC123 HCT 116 C239(1.14)  LDD0558  [7]
 LDCM0242  AC124 HCT 116 C239(1.08)  LDD0559  [7]
 LDCM0243  AC125 HCT 116 C239(0.92)  LDD0560  [7]
 LDCM0244  AC126 HCT 116 C239(0.95)  LDD0561  [7]
 LDCM0245  AC127 HCT 116 C239(1.11)  LDD0562  [7]
 LDCM0246  AC128 HCT 116 C239(1.21)  LDD0563  [7]
 LDCM0247  AC129 HCT 116 C239(1.33)  LDD0564  [7]
 LDCM0249  AC130 HCT 116 C239(1.13)  LDD0566  [7]
 LDCM0250  AC131 HCT 116 C239(1.12)  LDD0567  [7]
 LDCM0251  AC132 HCT 116 C239(1.31)  LDD0568  [7]
 LDCM0252  AC133 HCT 116 C239(1.12)  LDD0569  [7]
 LDCM0253  AC134 HCT 116 C239(1.14)  LDD0570  [7]
 LDCM0254  AC135 HCT 116 C239(1.25)  LDD0571  [7]
 LDCM0255  AC136 HCT 116 C239(1.11)  LDD0572  [7]
 LDCM0256  AC137 HCT 116 C239(1.20)  LDD0573  [7]
 LDCM0257  AC138 HCT 116 C239(0.91)  LDD0574  [7]
 LDCM0258  AC139 HCT 116 C239(1.24)  LDD0575  [7]
 LDCM0259  AC14 HCT 116 C239(0.83)  LDD0576  [7]
 LDCM0260  AC140 HCT 116 C239(1.45)  LDD0577  [7]
 LDCM0261  AC141 HCT 116 C239(1.17)  LDD0578  [7]
 LDCM0262  AC142 HCT 116 C239(1.14)  LDD0579  [7]
 LDCM0263  AC143 HCT 116 C239(0.97)  LDD0580  [7]
 LDCM0264  AC144 HCT 116 C239(1.00)  LDD0581  [7]
 LDCM0265  AC145 HCT 116 C239(1.03)  LDD0582  [7]
 LDCM0266  AC146 HCT 116 C239(1.06)  LDD0583  [7]
 LDCM0267  AC147 HCT 116 C239(0.95)  LDD0584  [7]
 LDCM0268  AC148 HCT 116 C239(0.91)  LDD0585  [7]
 LDCM0269  AC149 HCT 116 C239(0.92)  LDD0586  [7]
 LDCM0270  AC15 HCT 116 C239(1.20)  LDD0587  [7]
 LDCM0271  AC150 HCT 116 C239(1.04)  LDD0588  [7]
 LDCM0272  AC151 HCT 116 C239(1.04)  LDD0589  [7]
 LDCM0273  AC152 HCT 116 C239(0.98)  LDD0590  [7]
 LDCM0274  AC153 HCT 116 C239(1.11)  LDD0591  [7]
 LDCM0621  AC154 HCT 116 C239(1.15)  LDD2158  [7]
 LDCM0622  AC155 HCT 116 C239(1.05)  LDD2159  [7]
 LDCM0623  AC156 HCT 116 C239(1.08)  LDD2160  [7]
 LDCM0624  AC157 HCT 116 C239(1.07)  LDD2161  [7]
 LDCM0276  AC17 HCT 116 C239(1.12)  LDD0593  [7]
 LDCM0277  AC18 HCT 116 C239(1.05)  LDD0594  [7]
 LDCM0278  AC19 HCT 116 C239(1.13)  LDD0595  [7]
 LDCM0279  AC2 HEK-293T C331(1.07)  LDD1518  [16]
 LDCM0280  AC20 HCT 116 C239(0.99)  LDD0597  [7]
 LDCM0281  AC21 HCT 116 C239(1.17)  LDD0598  [7]
 LDCM0282  AC22 HCT 116 C239(1.01)  LDD0599  [7]
 LDCM0283  AC23 HCT 116 C239(1.12)  LDD0600  [7]
 LDCM0284  AC24 HCT 116 C239(1.04)  LDD0601  [7]
 LDCM0285  AC25 HCT 116 C239(1.12)  LDD0602  [7]
 LDCM0286  AC26 HCT 116 C239(0.97)  LDD0603  [7]
 LDCM0287  AC27 HCT 116 C239(1.05)  LDD0604  [7]
 LDCM0288  AC28 HCT 116 C239(0.97)  LDD0605  [7]
 LDCM0289  AC29 HCT 116 C239(0.97)  LDD0606  [7]
 LDCM0290  AC3 HEK-293T C331(0.88); C239(0.88)  LDD1529  [16]
 LDCM0291  AC30 HCT 116 C239(1.01)  LDD0608  [7]
 LDCM0292  AC31 HCT 116 C239(0.92)  LDD0609  [7]
 LDCM0293  AC32 HCT 116 C239(0.98)  LDD0610  [7]
 LDCM0294  AC33 HCT 116 C239(0.94)  LDD0611  [7]
 LDCM0295  AC34 HCT 116 C239(1.08)  LDD0612  [7]
 LDCM0296  AC35 HCT 116 C239(1.13)  LDD0613  [7]
 LDCM0297  AC36 HCT 116 C239(1.00)  LDD0614  [7]
 LDCM0298  AC37 HCT 116 C239(1.11)  LDD0615  [7]
 LDCM0299  AC38 HCT 116 C239(1.04)  LDD0616  [7]
 LDCM0300  AC39 HCT 116 C239(1.10)  LDD0617  [7]
 LDCM0301  AC4 HEK-293T C331(1.03); C116(1.12); C239(0.91)  LDD1540  [16]
 LDCM0302  AC40 HCT 116 C239(1.07)  LDD0619  [7]
 LDCM0303  AC41 HCT 116 C239(1.10)  LDD0620  [7]
 LDCM0304  AC42 HCT 116 C239(1.04)  LDD0621  [7]
 LDCM0305  AC43 HCT 116 C239(0.90)  LDD0622  [7]
 LDCM0306  AC44 HCT 116 C239(1.07)  LDD0623  [7]
 LDCM0307  AC45 HCT 116 C239(0.95)  LDD0624  [7]
 LDCM0308  AC46 HCT 116 C239(1.04)  LDD0625  [7]
 LDCM0309  AC47 HCT 116 C239(1.04)  LDD0626  [7]
 LDCM0310  AC48 HCT 116 C239(0.88)  LDD0627  [7]
 LDCM0311  AC49 HCT 116 C239(0.90)  LDD0628  [7]
 LDCM0312  AC5 HEK-293T C116(1.14)  LDD1551  [16]
 LDCM0313  AC50 HCT 116 C239(0.80)  LDD0630  [7]
 LDCM0314  AC51 HCT 116 C239(0.97)  LDD0631  [7]
 LDCM0315  AC52 HCT 116 C239(1.04)  LDD0632  [7]
 LDCM0316  AC53 HCT 116 C239(0.93)  LDD0633  [7]
 LDCM0317  AC54 HCT 116 C239(0.96)  LDD0634  [7]
 LDCM0318  AC55 HCT 116 C239(0.84)  LDD0635  [7]
 LDCM0319  AC56 HCT 116 C239(0.77)  LDD0636  [7]
 LDCM0320  AC57 HCT 116 C239(1.02)  LDD0637  [7]
 LDCM0321  AC58 HCT 116 C239(0.95)  LDD0638  [7]
 LDCM0322  AC59 HCT 116 C239(0.93)  LDD0639  [7]
 LDCM0323  AC6 HCT 116 C239(1.27)  LDD0640  [7]
 LDCM0324  AC60 HCT 116 C239(0.80)  LDD0641  [7]
 LDCM0325  AC61 HCT 116 C239(0.81)  LDD0642  [7]
 LDCM0326  AC62 HCT 116 C239(0.97)  LDD0643  [7]
 LDCM0327  AC63 HCT 116 C239(0.95)  LDD0644  [7]
 LDCM0328  AC64 HCT 116 C239(0.89)  LDD0645  [7]
 LDCM0329  AC65 HCT 116 C239(1.04)  LDD0646  [7]
 LDCM0330  AC66 HCT 116 C239(0.94)  LDD0647  [7]
 LDCM0331  AC67 HCT 116 C239(0.75)  LDD0648  [7]
 LDCM0332  AC68 HCT 116 C239(0.93)  LDD0649  [7]
 LDCM0333  AC69 HCT 116 C239(0.97)  LDD0650  [7]
 LDCM0334  AC7 HCT 116 C239(1.11)  LDD0651  [7]
 LDCM0335  AC70 HCT 116 C239(0.81)  LDD0652  [7]
 LDCM0336  AC71 HCT 116 C239(1.00)  LDD0653  [7]
 LDCM0337  AC72 HCT 116 C239(1.03)  LDD0654  [7]
 LDCM0338  AC73 HCT 116 C239(0.80)  LDD0655  [7]
 LDCM0339  AC74 HCT 116 C239(0.79)  LDD0656  [7]
 LDCM0340  AC75 HCT 116 C239(0.76)  LDD0657  [7]
 LDCM0341  AC76 HCT 116 C239(0.90)  LDD0658  [7]
 LDCM0342  AC77 HCT 116 C239(0.96)  LDD0659  [7]
 LDCM0343  AC78 HCT 116 C239(0.90)  LDD0660  [7]
 LDCM0344  AC79 HCT 116 C239(1.07)  LDD0661  [7]
 LDCM0345  AC8 HCT 116 C239(1.04)  LDD0662  [7]
 LDCM0346  AC80 HCT 116 C239(1.01)  LDD0663  [7]
 LDCM0347  AC81 HCT 116 C239(0.86)  LDD0664  [7]
 LDCM0348  AC82 HCT 116 C239(0.79)  LDD0665  [7]
 LDCM0349  AC83 HCT 116 C239(0.72)  LDD0666  [7]
 LDCM0350  AC84 HCT 116 C239(0.70)  LDD0667  [7]
 LDCM0351  AC85 HCT 116 C239(0.73)  LDD0668  [7]
 LDCM0352  AC86 HCT 116 C239(0.93)  LDD0669  [7]
 LDCM0353  AC87 HCT 116 C239(0.86)  LDD0670  [7]
 LDCM0354  AC88 HCT 116 C239(0.86)  LDD0671  [7]
 LDCM0355  AC89 HCT 116 C239(0.87)  LDD0672  [7]
 LDCM0357  AC90 HCT 116 C239(0.95)  LDD0674  [7]
 LDCM0358  AC91 HCT 116 C239(0.76)  LDD0675  [7]
 LDCM0359  AC92 HCT 116 C239(0.85)  LDD0676  [7]
 LDCM0360  AC93 HCT 116 C239(0.90)  LDD0677  [7]
 LDCM0361  AC94 HCT 116 C239(0.86)  LDD0678  [7]
 LDCM0362  AC95 HCT 116 C239(0.80)  LDD0679  [7]
 LDCM0363  AC96 HCT 116 C239(0.76)  LDD0680  [7]
 LDCM0364  AC97 HCT 116 C239(0.87)  LDD0681  [7]
 LDCM0365  AC98 HCT 116 C239(0.68)  LDD0682  [7]
 LDCM0366  AC99 HCT 116 C239(0.93)  LDD0683  [7]
 LDCM0248  AKOS034007472 HCT 116 C239(1.38)  LDD0565  [7]
 LDCM0356  AKOS034007680 HCT 116 C239(1.02)  LDD0673  [7]
 LDCM0275  AKOS034007705 HCT 116 C239(1.10)  LDD0592  [7]
 LDCM0156  Aniline NCI-H1299 11.58  LDD0403  [1]
 LDCM0630  CCW28-3 231MFP C222(1.24)  LDD2214  [17]
 LDCM0367  CL1 HCT 116 C239(1.32)  LDD0684  [7]
 LDCM0368  CL10 HCT 116 C239(0.76)  LDD0685  [7]
 LDCM0369  CL100 HEK-293T C331(1.19); C116(1.05); C239(1.09); C222(1.14)  LDD1573  [16]
 LDCM0370  CL101 HCT 116 C239(0.95)  LDD0687  [7]
 LDCM0371  CL102 HCT 116 C239(1.28)  LDD0688  [7]
 LDCM0372  CL103 HCT 116 C239(1.03)  LDD0689  [7]
 LDCM0373  CL104 HCT 116 C239(0.95)  LDD0690  [7]
 LDCM0374  CL105 HCT 116 C239(1.32)  LDD0691  [7]
 LDCM0375  CL106 HCT 116 C239(0.96)  LDD0692  [7]
 LDCM0376  CL107 HCT 116 C239(1.00)  LDD0693  [7]
 LDCM0377  CL108 HCT 116 C239(1.08)  LDD0694  [7]
 LDCM0378  CL109 HCT 116 C239(1.13)  LDD0695  [7]
 LDCM0379  CL11 HCT 116 C239(0.82)  LDD0696  [7]
 LDCM0380  CL110 HCT 116 C239(1.07)  LDD0697  [7]
 LDCM0381  CL111 HCT 116 C239(0.88)  LDD0698  [7]
 LDCM0382  CL112 HCT 116 C239(1.05)  LDD0699  [7]
 LDCM0383  CL113 HCT 116 C239(0.89)  LDD0700  [7]
 LDCM0384  CL114 HCT 116 C239(0.95)  LDD0701  [7]
 LDCM0385  CL115 HCT 116 C239(0.99)  LDD0702  [7]
 LDCM0386  CL116 HCT 116 C239(0.93)  LDD0703  [7]
 LDCM0387  CL117 HCT 116 C239(1.00)  LDD0704  [7]
 LDCM0388  CL118 HCT 116 C239(0.99)  LDD0705  [7]
 LDCM0389  CL119 HCT 116 C239(1.00)  LDD0706  [7]
 LDCM0390  CL12 HCT 116 C239(0.86)  LDD0707  [7]
 LDCM0391  CL120 HCT 116 C239(1.08)  LDD0708  [7]
 LDCM0392  CL121 HCT 116 C239(0.89)  LDD0709  [7]
 LDCM0393  CL122 HCT 116 C239(0.90)  LDD0710  [7]
 LDCM0394  CL123 HCT 116 C239(0.96)  LDD0711  [7]
 LDCM0395  CL124 HCT 116 C239(0.96)  LDD0712  [7]
 LDCM0396  CL125 HCT 116 C239(1.00)  LDD0713  [7]
 LDCM0397  CL126 HCT 116 C239(1.01)  LDD0714  [7]
 LDCM0398  CL127 HCT 116 C239(0.87)  LDD0715  [7]
 LDCM0399  CL128 HCT 116 C239(0.99)  LDD0716  [7]
 LDCM0400  CL13 HCT 116 C239(0.80)  LDD0717  [7]
 LDCM0401  CL14 HCT 116 C239(1.19)  LDD0718  [7]
 LDCM0402  CL15 HCT 116 C239(0.78)  LDD0719  [7]
 LDCM0403  CL16 HCT 116 C239(0.84)  LDD0720  [7]
 LDCM0404  CL17 HCT 116 C239(1.24)  LDD0721  [7]
 LDCM0405  CL18 HCT 116 C239(1.04)  LDD0722  [7]
 LDCM0406  CL19 HCT 116 C239(0.89)  LDD0723  [7]
 LDCM0407  CL2 HCT 116 C239(1.15)  LDD0724  [7]
 LDCM0408  CL20 HCT 116 C239(1.09)  LDD0725  [7]
 LDCM0409  CL21 HCT 116 C239(1.07)  LDD0726  [7]
 LDCM0410  CL22 HCT 116 C239(0.84)  LDD0727  [7]
 LDCM0411  CL23 HCT 116 C239(0.94)  LDD0728  [7]
 LDCM0412  CL24 HCT 116 C239(0.99)  LDD0729  [7]
 LDCM0413  CL25 HCT 116 C239(1.44)  LDD0730  [7]
 LDCM0414  CL26 HCT 116 C239(1.11)  LDD0731  [7]
 LDCM0415  CL27 HCT 116 C239(1.01)  LDD0732  [7]
 LDCM0416  CL28 HCT 116 C239(1.22)  LDD0733  [7]
 LDCM0417  CL29 HCT 116 C239(0.93)  LDD0734  [7]
 LDCM0418  CL3 HCT 116 C239(1.09)  LDD0735  [7]
 LDCM0419  CL30 HCT 116 C239(1.15)  LDD0736  [7]
 LDCM0420  CL31 HCT 116 C239(1.10)  LDD0737  [7]
 LDCM0421  CL32 HCT 116 C239(0.95)  LDD0738  [7]
 LDCM0422  CL33 HCT 116 C239(0.86)  LDD0739  [7]
 LDCM0423  CL34 HCT 116 C239(0.87)  LDD0740  [7]
 LDCM0424  CL35 HCT 116 C239(0.93)  LDD0741  [7]
 LDCM0425  CL36 HCT 116 C239(0.96)  LDD0742  [7]
 LDCM0426  CL37 HCT 116 C239(0.99)  LDD0743  [7]
 LDCM0428  CL39 HCT 116 C239(0.87)  LDD0745  [7]
 LDCM0429  CL4 HCT 116 C239(0.86)  LDD0746  [7]
 LDCM0430  CL40 HCT 116 C239(1.24)  LDD0747  [7]
 LDCM0431  CL41 HCT 116 C239(1.04)  LDD0748  [7]
 LDCM0432  CL42 HCT 116 C239(0.83)  LDD0749  [7]
 LDCM0433  CL43 HCT 116 C239(0.96)  LDD0750  [7]
 LDCM0434  CL44 HCT 116 C239(0.88)  LDD0751  [7]
 LDCM0435  CL45 HCT 116 C239(0.93)  LDD0752  [7]
 LDCM0436  CL46 HCT 116 C239(1.07)  LDD0753  [7]
 LDCM0437  CL47 HCT 116 C239(0.97)  LDD0754  [7]
 LDCM0438  CL48 HCT 116 C239(0.95)  LDD0755  [7]
 LDCM0439  CL49 HCT 116 C239(1.13)  LDD0756  [7]
 LDCM0440  CL5 HCT 116 C239(0.95)  LDD0757  [7]
 LDCM0441  CL50 HCT 116 C239(1.08)  LDD0758  [7]
 LDCM0442  CL51 HCT 116 C239(1.12)  LDD0759  [7]
 LDCM0443  CL52 HCT 116 C239(1.05)  LDD0760  [7]
 LDCM0444  CL53 HCT 116 C239(1.06)  LDD0761  [7]
 LDCM0445  CL54 HCT 116 C239(1.07)  LDD0762  [7]
 LDCM0446  CL55 HCT 116 C239(1.02)  LDD0763  [7]
 LDCM0447  CL56 HCT 116 C239(1.06)  LDD0764  [7]
 LDCM0448  CL57 HCT 116 C239(1.23)  LDD0765  [7]
 LDCM0449  CL58 HCT 116 C239(1.04)  LDD0766  [7]
 LDCM0450  CL59 HCT 116 C239(0.99)  LDD0767  [7]
 LDCM0451  CL6 HCT 116 C239(0.81)  LDD0768  [7]
 LDCM0452  CL60 HCT 116 C239(1.03)  LDD0769  [7]
 LDCM0453  CL61 HCT 116 C239(1.03)  LDD0770  [7]
 LDCM0454  CL62 HCT 116 C239(1.07)  LDD0771  [7]
 LDCM0455  CL63 HCT 116 C239(1.29)  LDD0772  [7]
 LDCM0456  CL64 HCT 116 C239(1.11)  LDD0773  [7]
 LDCM0457  CL65 HCT 116 C239(1.11)  LDD0774  [7]
 LDCM0458  CL66 HCT 116 C239(1.06)  LDD0775  [7]
 LDCM0459  CL67 HCT 116 C239(1.09)  LDD0776  [7]
 LDCM0460  CL68 HCT 116 C239(0.90)  LDD0777  [7]
 LDCM0461  CL69 HCT 116 C239(1.05)  LDD0778  [7]
 LDCM0462  CL7 HCT 116 C239(0.90)  LDD0779  [7]
 LDCM0463  CL70 HCT 116 C239(0.92)  LDD0780  [7]
 LDCM0464  CL71 HCT 116 C239(1.05)  LDD0781  [7]
 LDCM0465  CL72 HCT 116 C239(0.95)  LDD0782  [7]
 LDCM0466  CL73 HCT 116 C239(1.08)  LDD0783  [7]
 LDCM0467  CL74 HCT 116 C239(1.16)  LDD0784  [7]
 LDCM0469  CL76 HCT 116 C239(0.97)  LDD0786  [7]
 LDCM0470  CL77 HCT 116 C239(1.12)  LDD0787  [7]
 LDCM0471  CL78 HCT 116 C239(1.09)  LDD0788  [7]
 LDCM0472  CL79 HCT 116 C239(1.04)  LDD0789  [7]
 LDCM0473  CL8 HCT 116 C239(0.94)  LDD0790  [7]
 LDCM0474  CL80 HCT 116 C239(1.17)  LDD0791  [7]
 LDCM0475  CL81 HCT 116 C239(1.20)  LDD0792  [7]
 LDCM0476  CL82 HCT 116 C239(1.18)  LDD0793  [7]
 LDCM0477  CL83 HCT 116 C239(1.01)  LDD0794  [7]
 LDCM0478  CL84 HCT 116 C239(1.06)  LDD0795  [7]
 LDCM0479  CL85 HCT 116 C239(0.99)  LDD0796  [7]
 LDCM0480  CL86 HCT 116 C239(1.01)  LDD0797  [7]
 LDCM0481  CL87 HCT 116 C239(1.24)  LDD0798  [7]
 LDCM0482  CL88 HCT 116 C239(1.13)  LDD0799  [7]
 LDCM0483  CL89 HCT 116 C239(1.04)  LDD0800  [7]
 LDCM0484  CL9 HCT 116 C239(1.02)  LDD0801  [7]
 LDCM0485  CL90 HCT 116 C239(0.95)  LDD0802  [7]
 LDCM0486  CL91 HEK-293T C331(1.19); C239(1.07)  LDD1689  [16]
 LDCM0487  CL92 HEK-293T C331(1.04); C116(1.11); C239(1.04)  LDD1690  [16]
 LDCM0488  CL93 HEK-293T C116(1.01)  LDD1691  [16]
 LDCM0489  CL94 HEK-293T C331(1.09); C239(1.07)  LDD1692  [16]
 LDCM0490  CL95 HEK-293T C239(1.03)  LDD1693  [16]
 LDCM0491  CL96 HEK-293T C331(0.97)  LDD1694  [16]
 LDCM0492  CL97 HEK-293T C331(1.01)  LDD1695  [16]
 LDCM0493  CL98 HEK-293T C331(0.89)  LDD1696  [16]
 LDCM0494  CL99 HEK-293T C331(0.88); C116(0.96)  LDD1697  [16]
 LDCM0495  E2913 HEK-293T C331(0.72); C116(1.16)  LDD1698  [16]
 LDCM0625  F8 Ramos C331(0.46)  LDD2187  [18]
 LDCM0576  Fragment14 Ramos C331(1.21)  LDD2193  [18]
 LDCM0468  Fragment33 HCT 116 C239(1.09)  LDD0785  [7]
 LDCM0566  Fragment4 Ramos C331(0.70)  LDD2184  [18]
 LDCM0427  Fragment51 HCT 116 C239(1.08)  LDD0744  [7]
 LDCM0569  Fragment7 Ramos C331(0.60)  LDD2186  [18]
 LDCM0022  KB02 HEK-293T C239(1.01); C331(1.13)  LDD1492  [16]
 LDCM0023  KB03 HEK-293T C239(1.15); C331(1.03)  LDD1497  [16]
 LDCM0024  KB05 HMCB C331(1.60)  LDD3312  [19]
 LDCM0014  Panhematin HEK-293T 3.27  LDD0062  [5]

References

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Mass spectrometry data entry: PXD034651
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Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD028853
9 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
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11 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
12 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
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Mass spectrometry data entry: PXD007570
15 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
16 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
17 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
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Mass spectrometry data entry: PXD027578
19 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840