Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C349  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 172 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00697  Cytochrome b5 type B (CYB5B) 99.7
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 76.1
 LDTP03540  Heme oxygenase 2 (HMOX2) 75.6
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 62.7
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 54.2
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 51.6
 LDTP02359  Heme oxygenase 1 (HMOX1) 49.5
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 48.2
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 47.2
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 47.2
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) 44.9
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 44.3
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 41.9
 LDTP00907  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) 41.9
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 41.6
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 41.6
 LDTP10329  Ceramide synthase 2 (CERS2) 40.8
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 39.9
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 39.4
 LDTP09799  DCN1-like protein 4 (DCUN1D4) 38.1
 LDTP05758  S-methyl-5'-thioadenosine phosphorylase (MTAP) 36.3
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2) 35.0
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 33.8
 LDTP05396  Histone-lysine N-methyltransferase 2A (KMT2A) 33.6
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 31.3
 LDTP08859  Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) 31.3
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 30.3
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 29.4
 LDTP06142  Squalene monooxygenase (SQLE) 29.4
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 28.8
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 28.2
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 27.7
 LDTP13358  Leucyl-cystinyl aminopeptidase (LNPEP) 27.3
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 26.4
 LDTP05905  Acid ceramidase (ASAH1) 26.2
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 26.2
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 25.1
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 24.1
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 23.8
 LDTP02505  Lysosomal protective protein (CTSA) 23.6
 LDTP04358  Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) 22.9
 LDTP02000  3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) 22.3
 LDTP09188  Lysophosphatidylcholine acyltransferase 1 (LPCAT1) 21.3
 LDTP12639  1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) 21.1
 LDTP03189  Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) 21.1
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 21.1
 LDTP09043  Lysine-specific histone demethylase 2 (KDM1B) 20.8
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 20.8
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 20.5
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 20.5
 LDTP09088  Phospholipase A2 group XV (PLA2G15) 20.4
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 20.3
 LDTP01743  NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) 19.6
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 19.0
 LDTP01329  Lathosterol oxidase (SC5D) 18.8
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 18.6
 LDTP06618  ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) 18.0
 LDTP06977  GPI ethanolamine phosphate transferase 2 (PIGG) 18.0
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 18.0
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS) 18.0
 LDTP11852  Presenilin-associated rhomboid-like protein, mitochondrial (PARL) 17.9
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 17.8
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 17.1
 LDTP13486  Long-chain-fatty-acid--CoA ligase 6 (ACSL6) 17.1
 LDTP03145  Catechol O-methyltransferase (COMT) 17.0
 LDTP11273  N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) 17.0
 LDTP06849  Prolyl endopeptidase-like (PREPL) 17.0
 LDTP15879  Haloacid dehalogenase-like hydrolase domain-containing protein 3 (HDHD3) 16.9
 LDTP04634  Alpha-N-acetylglucosaminidase (NAGLU) 16.8
 LDTP11437  Peroxisomal trans-2-enoyl-CoA reductase (PECR) 16.7
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 16.4
 LDTP07931  Heme A synthase COX15 (COX15) 15.9
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 15.8
 LDTP08455  Palmitoyltransferase ZDHHC13 (ZDHHC13) 15.7
 LDTP08378  Serine/threonine-protein kinase VRK2 (VRK2) 15.3
 LDTP10471  Protein disulfide-isomerase TMX3 (TMX3) 15.1
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 15.0
 LDTP09396  Minor histocompatibility antigen H13 (HM13) 14.8
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) 14.7
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) 14.5
 LDTP09814  Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) 14.4
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 14.4
 LDTP01704  Phosphatidylserine lipase ABHD16A (ABHD16A) 14.4
 LDTP09251  Atlastin-2 (ATL2) 14.1
 LDTP02837  Beta-galactosidase (GLB1) 14.1
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 14.1
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 14.0
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 13.7
 LDTP06370  Ephrin type-A receptor 7 (EPHA7) 13.5
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 13.5
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 13.5
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 13.5
 LDTP12851  UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1) 13.5
 LDTP00950  Dynamin-like 120 kDa protein, mitochondrial (OPA1) 13.4
 LDTP03769  Sterol O-acyltransferase 1 (SOAT1) 13.2
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 13.1
 LDTP03394  Ceramide synthase 1 (CERS1) 12.9
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 12.6
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 12.6
 LDTP00783  Beta-1,4-glucuronyltransferase 1 (B4GAT1) 12.6
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1) 12.6
 LDTP08203  E3 ubiquitin-protein ligase synoviolin (SYVN1) 12.2
 LDTP15988  Probable serine carboxypeptidase CPVL (CPVL) 12.2
 LDTP08799  Lysophosphatidylserine lipase ABHD12 (ABHD12) 12.0
 LDTP04247  Protein farnesyltransferase subunit beta (FNTB) 12.0
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 11.9
 LDTP15097  All-trans-retinol 13,14-reductase (RETSAT) 11.8
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 11.8
 LDTP12720  Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) 11.8
 LDTP04203  Phosphatidylserine synthase 1 (PTDSS1) 11.8
 LDTP10020  Ras-related protein Rab-24 (RAB24) 11.7
 LDTP04895  Ras-related protein Rab-10 (RAB10) 11.5
 LDTP06315  Platelet-activating factor acetylhydrolase IB subunit alpha1 (PAFAH1B3) 11.4
 LDTP04531  Hexokinase-2 (HK2) 11.2
 LDTP00988  Protein O-GlcNAcase (OGA) 11.2
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 11.2
 LDTP01707  Thioredoxin domain-containing protein 12 (TXNDC12) 11.2
 LDTP05409  Antigen peptide transporter 2 (TAP2) 11.2
 LDTP07154  ATPase family AAA domain-containing protein 3B (ATAD3B) 11.1
 LDTP00464  Glutathione S-transferase 3, mitochondrial (MGST3) 11.1
 LDTP08790  Mitochondrial cardiolipin hydrolase (PLD6) 11.1
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 11.1
 LDTP09835  GPI-anchor transamidase (PIGK) 11.0
 LDTP04581  Holocytochrome c-type synthase (HCCS) 11.0
 LDTP01335  Protein SCO1 homolog, mitochondrial (SCO1) 11.0
 LDTP14030  V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) 11.0
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 10.8
 LDTP04114  E3 ubiquitin-protein ligase NEDD4 (NEDD4) 10.6
 LDTP10249  Metalloendopeptidase OMA1, mitochondrial (OMA1) 10.6
 LDTP10966  Microsomal glutathione S-transferase 2 (MGST2) 10.6
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 10.4
 LDTP10930  Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) 10.4
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 10.3
 LDTP02486  Lysosomal alpha-glucosidase (GAA) 10.3
 LDTP02984  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) 10.2
 LDTP02254  ATP-dependent translocase ABCB1 (ABCB1) 10.1
 LDTP09388  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (STT3B) 10.1
 LDTP02499  Receptor-type tyrosine-protein phosphatase F (PTPRF) 10.1
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 10.1
 LDTP02362  Dihydrolipoyl dehydrogenase, mitochondrial (DLD) 10.1
 LDTP10550  Dehydrogenase/reductase SDR family member 1 (DHRS1) 10.0
 LDTP01168  NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) 10.0
 LDTP00344  Stearoyl-CoA desaturase (SCD) 10.0
 LDTP13131  7-dehydrocholesterol reductase (DHCR7) 9.9
 LDTP13352  GTP:AMP phosphotransferase AK3, mitochondrial (AK3) 9.9
 LDTP07679  Lysocardiolipin acyltransferase 1 (LCLAT1) 9.9
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 9.9
 LDTP09155  Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3) 9.8
 LDTP09495  Probable glutathione peroxidase 8 (GPX8) 9.8
 LDTP12608  Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) 9.7
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 9.7
 LDTP12293  Adipocyte plasma membrane-associated protein (APMAP) 9.6
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 9.6
 LDTP02799  N-acetylglucosamine-6-sulfatase (GNS) 9.6
 LDTP04925  Pterin-4-alpha-carbinolamine dehydratase (PCBD1) 9.5
 LDTP07227  Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) 9.5
 LDTP06721  GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) 9.4
 LDTP09256  Putative phospholipase B-like 2 (PLBD2) 9.3
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 9.2
 LDTP01699  Acyl-CoA 6-desaturase (FADS2) 9.1
 LDTP07003  Presequence protease, mitochondrial (PITRM1) 9.1
 LDTP07402  Dehydrogenase/reductase SDR family member 7B (DHRS7B) 8.9
 LDTP06150  DNA replication licensing factor MCM6 (MCM6) 8.8
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 8.7
 LDTP07961  Protein arginine methyltransferase NDUFAF7, mitochondrial (NDUFAF7) 8.7
 LDTP09063  Estradiol 17-beta-dehydrogenase 11 (HSD17B11) 8.6
 LDTP04569  Geranylgeranyl transferase type-2 subunit beta (RABGGTB) 8.6
 LDTP12867  Very-long-chain enoyl-CoA reductase (TECR) 8.6
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 8.5
 LDTP04333  GMP synthase [glutamine-hydrolyzing] (GMPS) 8.5
 LDTP09000  Lysophospholipase D GDPD1 (GDPD1) 8.5
 LDTP04892  Ras-related protein Rab-2A (RAB2A) 8.5
Transporter and channel
Click to Show/Hide to Show 137 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 99.7
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 79.9
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 75.6
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 73.0
 LDTP06633  Reticulon-1 (RTN1) 72.5
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 72.0
 LDTP01804  ATP synthase subunit a (MT-ATP6) 71.0
 LDTP11615  Protein tweety homolog 3 (TTYH3) 70.5
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 70.5
 LDTP11245  Derlin-1 (DERL1) 65.3
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 62.2
 LDTP15481  Transmembrane protein 87A (TMEM87A) 52.3
 LDTP14099  Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) 50.9
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 48.8
 LDTP12207  Putative divalent cation/proton antiporter TMEM165 (TMEM165) 46.2
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 45.9
 LDTP16813  Tetraspanin-3 (TSPAN3) 43.1
 LDTP15948  Transmembrane protein 126A (TMEM126A) 41.4
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 39.7
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 38.1
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 37.5
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 35.3
 LDTP08881  Transmembrane protein 199 (TMEM199) 34.5
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 34.3
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 33.6
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 33.4
 LDTP10065  Transmembrane protein 230 (TMEM230) 33.1
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 28.2
 LDTP11250  MICOS complex subunit MIC26 (APOO) 27.5
 LDTP09294  Proton-coupled zinc antiporter SLC30A5 (SLC30A5) 26.0
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 25.5
 LDTP07531  Sideroflexin-4 (SFXN4) 24.4
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 23.9
 LDTP11213  Nucleoporin NDC1 (NDC1) 22.8
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 22.3
 LDTP06945  Sigma intracellular receptor 2 (TMEM97) 22.3
 LDTP06221  StAR-related lipid transfer protein 3 (STARD3) 22.2
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 21.1
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 21.0
 LDTP07236  Protein GPR107 (GPR107) 20.5
 LDTP05900  Metaxin-1 (MTX1) 20.3
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 20.1
 LDTP04787  Transmembrane protein 33 (TMEM33) 19.7
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 19.6
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 19.4
 LDTP01060  PRA1 family protein 2 (PRAF2) 19.0
 LDTP08469  Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) 18.9
 LDTP14200  Mitochondrial ornithine transporter 1 (SLC25A15) 18.9
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 18.8
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 18.5
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 18.5
 LDTP00541  NPC intracellular cholesterol transporter 1 (NPC1) 17.9
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 17.5
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 17.4
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 17.1
 LDTP12704  Anoctamin-10 (ANO10) 16.8
 LDTP18459  StAR-related lipid transfer protein 7, mitochondrial (STARD7) 16.3
 LDTP00857  Syntaxin-6 (STX6) 16.3
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 15.9
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 15.3
 LDTP06365  Transmembrane emp24 domain-containing protein 2 (TMED2) 15.3
 LDTP10731  Sodium-coupled neutral amino acid symporter 2 (SLC38A2) 15.1
 LDTP10073  Protein RFT1 homolog (RFT1) 15.0
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 14.6
 LDTP13969  Transmembrane emp24 domain-containing protein 7 (TMED7) 14.6
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 14.2
 LDTP04227  Guided entry of tail-anchored proteins factor CAMLG (CAMLG) 14.1
 LDTP01454  SUN domain-containing protein 1 (SUN1) 14.1
 LDTP07462  MFS-type transporter SLC18B1 (SLC18B1) 13.8
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) 13.6
 LDTP07064  Nucleoporin NUP188 (NUP188) 13.6
 LDTP14970  Metaxin-3 (MTX3) 13.5
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 13.4
 LDTP10343  Vacuole membrane protein 1 (VMP1) 13.4
 LDTP01217  Metaxin-2 (MTX2) 13.2
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 13.2
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 12.7
 LDTP03559  High affinity cationic amino acid transporter 1 (SLC7A1) 12.6
 LDTP07477  Transmembrane protein 214 (TMEM214) 12.5
 LDTP15979  Transmembrane protein 245 (TMEM245) 12.4
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 12.2
 LDTP12451  Integral membrane protein 2C (ITM2C) 12.2
 LDTP10804  Chloride channel CLIC-like protein 1 (CLCC1) 12.0
 LDTP00970  Gasdermin-E (GSDME) 11.8
 LDTP07058  Transmembrane protein 201 (TMEM201) 11.8
 LDTP07537  Metal transporter CNNM4 (CNNM4) 11.7
 LDTP15845  Transmembrane 9 superfamily member 2 (TM9SF2) 11.6
 LDTP11095  Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) 11.6
 LDTP00547  Secretory carrier-associated membrane protein 2 (SCAMP2) 11.4
 LDTP00821  Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) 11.0
 LDTP09203  Nucleoporin Nup37 (NUP37) 11.0
 LDTP00590  Protein RER1 (RER1) 11.0
 LDTP04956  Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) 10.9
 LDTP09987  Secretory carrier-associated membrane protein 4 (SCAMP4) 10.9
 LDTP02087  ADP/ATP translocase 2 (SLC25A5) 10.7
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 10.7
 LDTP18153  Major facilitator superfamily domain-containing protein 3 (MFSD3) 10.6
 LDTP14717  ATP synthase subunit e, mitochondrial (ATP5ME) 10.4
 LDTP14084  Sorting and assembly machinery component 50 homolog (SAMM50) 10.4
 LDTP03380  Stomatin (STOM) 10.4
 LDTP13943  Thioredoxin-related transmembrane protein 2 (TMX2) 10.4
 LDTP09288  Vang-like protein 1 (VANGL1) 10.4
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 10.3
 LDTP12383  Protein GPR108 (GPR108) 10.3
 LDTP09333  Golgin subfamily A member 5 (GOLGA5) 10.2
 LDTP01352  PRA1 family protein 3 (ARL6IP5) 10.2
 LDTP06499  V-type proton ATPase subunit S1 (ATP6AP1) 10.2
 LDTP12090  Sideroflexin-1 (SFXN1) 10.1
 LDTP15838  Translocation protein SEC62 (SEC62) 9.8
 LDTP00405  Etoposide-induced protein 2.4 homolog (EI24) 9.7
 LDTP12272  Prolactin regulatory element-binding protein (PREB) 9.7
 LDTP11281  Voltage-gated monoatomic cation channel TMEM109 (TMEM109) 9.7
 LDTP04237  Protein ERGIC-53 (LMAN1) 9.6
 LDTP00262  Acetyl-coenzyme A transporter 1 (SLC33A1) 9.5
 LDTP06660  MICOS complex subunit MIC60 (IMMT) 9.4
 LDTP10621  Sideroflexin-2 (SFXN2) 9.4
 LDTP17641  Solute carrier family 35 member F2 (SLC35F2) 9.4
 LDTP00592  Surfeit locus protein 4 (SURF4) 9.4
 LDTP01100  Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) 9.3
 LDTP12661  Exocyst complex component 1 (EXOC1) 9.2
 LDTP10769  Intermembrane lipid transfer protein VPS13A (VPS13A) 9.1
 LDTP06293  Metal cation symporter ZIP14 (SLC39A14) 9.1
 LDTP12809  Solute carrier family 2, facilitated glucose transporter member 8 (SLC2A8) 9.1
 LDTP04459  H(+)/Cl(-) exchange transporter 3 (CLCN3) 9.0
 LDTP00383  AP-3 complex subunit delta-1 (AP3D1) 8.9
 LDTP03405  Calnexin (CANX) 8.9
 LDTP04426  B-cell receptor-associated protein 31 (BCAP31) 8.8
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 8.8
 LDTP01200  Peroxisomal membrane protein PEX14 (PEX14) 8.8
 LDTP10885  Sortilin (SORT1) 8.8
 LDTP07002  Transport and Golgi organization protein 1 homolog (MIA3) 8.8
 LDTP09204  Nucleoporin NUP35 (NUP35) 8.6
 LDTP00872  Peroxisomal membrane protein PMP34 (SLC25A17) 8.6
 LDTP13599  Calcium load-activated calcium channel (TMCO1) 8.6
 LDTP11634  Derlin-2 (DERL2) 8.5
 LDTP07667  Transmembrane protein 205 (TMEM205) 8.5
 LDTP07583  Transmembrane protein 65 (TMEM65) 8.5
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 20.1
Immunoglobulin
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04720  IgG receptor FcRn large subunit p51 (FCGRT) 21.9
 LDTP05572  Leukocyte surface antigen CD47 (CD47) 20.7
Other
Click to Show/Hide to Show 106 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 99.7
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 94.4
 LDTP11076  Apolipoprotein L2 (APOL2) 91.8
 LDTP00850  ER lumen protein-retaining receptor 3 (KDELR3) 88.0
 LDTP14458  Tetraspanin-6 (TSPAN6) 81.6
 LDTP05160  Nucleobindin-2 (NUCB2) 64.9
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 63.6
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 61.8
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 58.9
 LDTP08224  Protein LYRIC (MTDH) 52.0
 LDTP01522  Reticulon-3 (RTN3) 49.2
 LDTP13086  Syntaxin-18 (STX18) 42.8
 LDTP12412  Reticulon-4 (RTN4) 41.4
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 38.9
 LDTP10056  Protein FAM162A (FAM162A) 38.9
 LDTP00986  Syntaxin-10 (STX10) 38.1
 LDTP01167  Reticulon-2 (RTN2) 37.5
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 34.8
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 34.8
 LDTP18272  Transmembrane protein 209 (TMEM209) 30.3
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 29.7
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 29.4
 LDTP15398  Protein FAM177A1 (FAM177A1) 26.2
 LDTP01432  Mitochondrial import receptor subunit TOM70 (TOMM70) 25.1
 LDTP19963  TraB domain-containing protein (TRABD) 24.4
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 22.8
 LDTP09773  Protein FAM3C (FAM3C) 22.3
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 22.0
 LDTP08606  Nurim (NRM) 21.0
 LDTP01494  Protein YIF1A (YIF1A) 20.7
 LDTP06097  Reticulocalbin-2 (RCN2) 20.1
 LDTP07574  Superkiller complex protein 3 (SKIC3) 20.1
 LDTP15793  Protein FAM210A (FAM210A) 19.2
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 18.8
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 18.8
 LDTP16080  Protein FAM114A2 (FAM114A2) 18.5
 LDTP02927  Ganglioside GM2 activator (GM2A) 18.0
 LDTP07255  Proteasome adapter and scaffold protein ECM29 (ECPAS) 18.0
 LDTP17003  Matrix-remodeling-associated protein 7 (MXRA7) 17.1
 LDTP00859  Synaptogyrin-2 (SYNGR2) 17.0
 LDTP05375  Nucleobindin-1 (NUCB1) 16.9
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 16.9
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 15.2
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 15.1
 LDTP05868  Protein unc-119 homolog A (UNC119) 15.0
 LDTP04356  Emerin (EMD) 14.3
 LDTP14126  Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) 14.2
 LDTP07192  Intermembrane lipid transfer protein VPS13D (VPS13D) 14.0
 LDTP09297  Large ribosomal subunit protein mL64 (GADD45GIP1) 13.9
 LDTP01359  Dynactin subunit 3 (DCTN3) 13.5
 LDTP09215  Torsin-1A-interacting protein 2 (TOR1AIP2) 13.5
 LDTP00632  Syntaxin-7 (STX7) 13.4
 LDTP15887  Lipase maturation factor 2 (LMF2) 13.3
 LDTP13630  Neudesin (NENF) 13.2
 LDTP10775  Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) 13.0
 LDTP03967  Lamina-associated polypeptide 2, isoform alpha (TMPO) 12.8
 LDTP10924  Prohibitin-2 (PHB2) 12.5
 LDTP12379  Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) 12.4
 LDTP12571  LanC-like protein 2 (LANCL2) 12.3
 LDTP08154  Large ribosomal subunit protein uL10m (MRPL10) 12.1
 LDTP11167  Protein YIPF4 (YIPF4) 12.1
 LDTP12729  Required for meiotic nuclear division protein 1 homolog (RMND1) 12.1
 LDTP16285  Transducin beta-like protein 2 (TBL2) 12.1
 LDTP14136  Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13) 12.0
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) 12.0
 LDTP19372  Tetratricopeptide repeat protein 38 (TTC38) 11.7
 LDTP08707  Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) 11.6
 LDTP02205  Tubulin beta chain (TUBB) 11.6
 LDTP15269  Large ribosomal subunit protein mL55 (MRPL55) 11.4
 LDTP05715  Vesicle transport protein SEC20 (BNIP1) 11.3
 LDTP00500  Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) 11.2
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 11.2
 LDTP08594  Negative elongation factor C/D (NELFCD) 11.2
 LDTP12468  Diablo IAP-binding mitochondrial protein (DIABLO) 10.9
 LDTP16193  Craniofacial development protein 1 (CFDP1) 10.9
 LDTP16322  Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) 10.9
 LDTP09787  Nicastrin (NCSTN) 10.9
 LDTP00887  Calumenin (CALU) 10.8
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 10.8
 LDTP00913  Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) 10.7
 LDTP00871  Microtubule nucleation factor SSNA1 (SSNA1) 10.6
 LDTP00729  Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) 10.4
 LDTP07718  MICOS complex subunit MIC27 (APOOL) 10.4
 LDTP12677  DnaJ homolog subfamily C member 11 (DNAJC11) 10.3
 LDTP00573  Prefoldin subunit 6 (PFDN6) 10.3
 LDTP00046  NBAS subunit of NRZ tethering complex (NBAS) 10.3
 LDTP07368  Tetratricopeptide repeat protein 19, mitochondrial (TTC19) 10.2
 LDTP13125  Protein UXT (UXT) 10.0
 LDTP11277  Tubulin beta-2B chain (TUBB2B) 9.8
 LDTP02037  Tubulin beta-4A chain (TUBB4A) 9.7
 LDTP15863  Large ribosomal subunit protein mL45 (MRPL45) 9.6
 LDTP11981  Receptor expression-enhancing protein 4 (REEP4) 9.5
 LDTP08793  Armadillo repeat-containing protein 10 (ARMC10) 9.4
 LDTP09255  Motile sperm domain-containing protein 2 (MOSPD2) 9.4
 LDTP11906  Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) 9.3
 LDTP03775  RNA-binding protein FUS (FUS) 9.1
 LDTP13908  AP-3 complex subunit mu-1 (AP3M1) 9.1
 LDTP11911  Golgi phosphoprotein 3 (GOLPH3) 9.1
 LDTP01163  Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) 9.1
 LDTP05960  Trophoblast glycoprotein (TPBG) 9.0
 LDTP04207  Heat shock 70 kDa protein 13 (HSPA13) 8.9
 LDTP09850  Proline-rich protein PRCC (PRCC) 8.9
 LDTP04425  Translocon-associated protein subunit delta (SSR4) 8.9
 LDTP10965  Nucleosome assembly protein 1-like 4 (NAP1L4) 8.8
 LDTP03614  Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) 8.7
 LDTP04652  Eukaryotic translation initiation factor 5 (EIF5) 8.6

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587