Details of the Target

General Information of Target

Target ID LDTP11911
Target Name Golgi phosphoprotein 3 (GOLPH3)
Gene Name GOLPH3
Gene ID 64083
Synonyms
GPP34; Golgi phosphoprotein 3; Coat protein GPP34; Mitochondrial DNA absence factor; MIDAS
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
Download
Sequence
MTTLTHRARRTEISKNSEKKMESEEDSNWEKSPDNEDSGDSKDIRLTLMEEVLLLGLKDK
EGYTSFWNDCISSGLRGGILIELAMRGRIYLEPPTMRKKRLLDRKVLLKSDSPTGDVLLD
ETLKHIKATEPTETVQTWIELLTGETWNPFKLQYQLRNVRERIAKNLVEKGILTTEKQNF
LLFDMTTHPVTNTTEKQRLVKKLQDSVLERWVNDPQRMDKRTLALLVLAHSSDVLENVFS
SLTDDKYDVAMNRAKDLVELDPEVEGTKPSATEMIWAVLAAFNKS
Target Bioclass
Other
Family
GOLPH3/VPS74 family
Subcellular location
Golgi apparatus, Golgi stack membrane
Function
Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Has also been involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part. May play an indirect role in cell migration. Has also been involved in the modulation of mTOR signaling. May also be involved in the regulation of mitochondrial lipids biosynthesis.
Uniprot ID
Q9H4A6
Ensemble ID
ENST00000265070.7
HGNC ID
HGNC:15452

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 17 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K138(9.20)  LDD0277  [1]
m-APA
 Probe Info  		11.74  LDD0403  [2]
SAHA-CA-4PAP
 Probe Info  		4.50  LDD0360  [3]
BTD
 Probe Info  		C108(1.04)  LDD2093  [4]
DBIA
 Probe Info  		C84(1.14); C108(0.99)  LDD0078  [5]
5E-2FA
 Probe Info  		N.A.  LDD2235  [6]
4-Iodoacetamidophenylacetylene
 Probe Info  		C84(0.00); C92(0.00); C108(0.00); C280(0.00)  LDD0038  [7]
IA-alkyne
 Probe Info  		C84(0.00); C92(0.00); C108(0.00); C280(0.00)  LDD0036  [7]
Lodoacetamide azide
 Probe Info  		C84(0.00); C108(0.00); C280(0.00)  LDD0037  [7]
IPM
 Probe Info  		N.A.  LDD0025  [8]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [8]
TFBX
 Probe Info  		N.A.  LDD0148  [8]
Phosphinate-6
 Probe Info  		C108(0.00); C122(0.00)  LDD0018  [9]
Acrolein
 Probe Info  		N.A.  LDD0217  [10]
W1
 Probe Info  		C108(0.00); C280(0.00)  LDD0236  [11]
AOyne
 Probe Info  		15.00  LDD0443  [12]
NAIA_5
 Probe Info  		C92(0.00); C108(0.00); C280(0.00); C122(0.00)  LDD2223  [13]
PAL-AfBPP Probe
Click To Hide/Show 51 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C022
 Probe Info  		7.94  LDD1728  [14]
C040
 Probe Info  		13.45  LDD1740  [14]
C055
 Probe Info  		14.93  LDD1752  [14]
C056
 Probe Info  		19.16  LDD1753  [14]
C064
 Probe Info  		5.98  LDD1761  [14]
C091
 Probe Info  		16.45  LDD1782  [14]
C092
 Probe Info  		51.63  LDD1783  [14]
C094
 Probe Info  		35.02  LDD1785  [14]
C112
 Probe Info  		24.42  LDD1799  [14]
C134
 Probe Info  		33.13  LDD1816  [14]
C141
 Probe Info  		10.06  LDD1823  [14]
C143
 Probe Info  		18.90  LDD1825  [14]
C186
 Probe Info  		7.84  LDD1864  [14]
C218
 Probe Info  		16.00  LDD1892  [14]
C220
 Probe Info  		16.80  LDD1894  [14]
C229
 Probe Info  		9.51  LDD1902  [14]
C231
 Probe Info  		36.50  LDD1904  [14]
C232
 Probe Info  		75.58  LDD1905  [14]
C233
 Probe Info  		12.38  LDD1906  [14]
C234
 Probe Info  		8.34  LDD1907  [14]
C235
 Probe Info  		41.36  LDD1908  [14]
C238
 Probe Info  		15.67  LDD1911  [14]
C244
 Probe Info  		18.00  LDD1917  [14]
C246
 Probe Info  		16.22  LDD1919  [14]
C264
 Probe Info  		17.39  LDD1935  [14]
C265
 Probe Info  		13.45  LDD1936  [14]
C285
 Probe Info  		23.75  LDD1955  [14]
C287
 Probe Info  		9.06  LDD1957  [14]
C288
 Probe Info  		6.15  LDD1958  [14]
C289
 Probe Info  		76.64  LDD1959  [14]
C313
 Probe Info  		12.47  LDD1980  [14]
C349
 Probe Info  		9.06  LDD2010  [14]
C350
 Probe Info  		29.65  LDD2011  [14]
C362
 Probe Info  		61.82  LDD2023  [14]
C363
 Probe Info  		21.56  LDD2024  [14]
C364
 Probe Info  		24.42  LDD2025  [14]
C366
 Probe Info  		10.93  LDD2027  [14]
C367
 Probe Info  		5.35  LDD2028  [14]
C373
 Probe Info  		5.03  LDD2033  [14]
C388
 Probe Info  		54.95  LDD2047  [14]
C390
 Probe Info  		31.12  LDD2049  [14]
C399
 Probe Info  		6.77  LDD2058  [14]
C403
 Probe Info  		30.70  LDD2061  [14]
C407
 Probe Info  		23.43  LDD2064  [14]
FFF probe11
 Probe Info  		18.98  LDD0471  [15]
FFF probe13
 Probe Info  		8.19  LDD0476  [15]
FFF probe14
 Probe Info  		20.00  LDD0477  [15]
FFF probe2
 Probe Info  		20.00  LDD0463  [15]
FFF probe3
 Probe Info  		12.78  LDD0465  [15]
Alk-rapa
 Probe Info  		4.67  LDD0213  [16]
STS-1
 Probe Info  		N.A.  LDD0068  [17]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C108(0.82)  LDD2117  [4]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C108(1.38)  LDD2152  [4]
 LDCM0214  AC1 HCT 116 C108(1.04); C84(1.07); C92(1.38)  LDD0531  [5]
 LDCM0215  AC10 HCT 116 C108(1.20); C84(1.18); C92(1.00)  LDD0532  [5]
 LDCM0216  AC100 HCT 116 C108(1.11); C84(1.04)  LDD0533  [5]
 LDCM0217  AC101 HCT 116 C108(0.96); C84(1.09)  LDD0534  [5]
 LDCM0218  AC102 HCT 116 C108(0.99); C84(0.94)  LDD0535  [5]
 LDCM0219  AC103 HCT 116 C108(1.15); C84(1.12)  LDD0536  [5]
 LDCM0220  AC104 HCT 116 C108(1.14); C84(0.95)  LDD0537  [5]
 LDCM0221  AC105 HCT 116 C108(1.12); C84(1.37)  LDD0538  [5]
 LDCM0222  AC106 HCT 116 C108(1.31); C84(1.12)  LDD0539  [5]
 LDCM0223  AC107 HCT 116 C108(1.16); C84(1.05)  LDD0540  [5]
 LDCM0224  AC108 HCT 116 C108(1.21); C84(1.25)  LDD0541  [5]
 LDCM0225  AC109 HCT 116 C108(0.94); C84(1.11)  LDD0542  [5]
 LDCM0226  AC11 HCT 116 C108(1.28); C84(1.18); C92(1.57)  LDD0543  [5]
 LDCM0227  AC110 HCT 116 C108(1.13); C84(1.07)  LDD0544  [5]
 LDCM0228  AC111 HCT 116 C108(1.09); C84(1.11)  LDD0545  [5]
 LDCM0229  AC112 HCT 116 C108(1.10); C84(0.90)  LDD0546  [5]
 LDCM0230  AC113 HCT 116 C108(1.07); C84(0.86)  LDD0547  [5]
 LDCM0231  AC114 HCT 116 C108(1.03); C84(0.99)  LDD0548  [5]
 LDCM0232  AC115 HCT 116 C108(1.12); C84(1.14)  LDD0549  [5]
 LDCM0233  AC116 HCT 116 C108(1.27); C84(1.16)  LDD0550  [5]
 LDCM0234  AC117 HCT 116 C108(1.09); C84(1.09)  LDD0551  [5]
 LDCM0235  AC118 HCT 116 C108(1.07); C84(0.99)  LDD0552  [5]
 LDCM0236  AC119 HCT 116 C108(1.14); C84(1.22)  LDD0553  [5]
 LDCM0237  AC12 HCT 116 C108(1.04); C84(1.07); C92(1.19)  LDD0554  [5]
 LDCM0238  AC120 HCT 116 C108(1.10); C84(1.05)  LDD0555  [5]
 LDCM0239  AC121 HCT 116 C108(1.00); C84(1.00)  LDD0556  [5]
 LDCM0240  AC122 HCT 116 C108(1.22); C84(1.20)  LDD0557  [5]
 LDCM0241  AC123 HCT 116 C108(0.97); C84(0.97)  LDD0558  [5]
 LDCM0242  AC124 HCT 116 C108(1.08); C84(1.05)  LDD0559  [5]
 LDCM0243  AC125 HCT 116 C108(1.18); C84(1.18)  LDD0560  [5]
 LDCM0244  AC126 HCT 116 C108(1.18); C84(1.19)  LDD0561  [5]
 LDCM0245  AC127 HCT 116 C108(1.22); C84(1.05)  LDD0562  [5]
 LDCM0246  AC128 HCT 116 C108(1.44); C84(1.16)  LDD0563  [5]
 LDCM0247  AC129 HCT 116 C108(1.05); C84(0.88)  LDD0564  [5]
 LDCM0249  AC130 HCT 116 C108(1.40); C84(1.11)  LDD0566  [5]
 LDCM0250  AC131 HCT 116 C108(0.93); C84(0.91)  LDD0567  [5]
 LDCM0251  AC132 HCT 116 C108(1.38); C84(1.13)  LDD0568  [5]
 LDCM0252  AC133 HCT 116 C108(1.37); C84(1.08)  LDD0569  [5]
 LDCM0253  AC134 HCT 116 C108(1.61); C84(1.12)  LDD0570  [5]
 LDCM0254  AC135 HCT 116 C108(1.38); C84(1.06)  LDD0571  [5]
 LDCM0255  AC136 HCT 116 C108(1.38); C84(1.05)  LDD0572  [5]
 LDCM0256  AC137 HCT 116 C108(1.52); C84(1.08)  LDD0573  [5]
 LDCM0257  AC138 HCT 116 C108(1.64); C84(1.08)  LDD0574  [5]
 LDCM0258  AC139 HCT 116 C108(1.44); C84(1.16)  LDD0575  [5]
 LDCM0259  AC14 HCT 116 C108(0.95); C84(1.33); C92(1.14)  LDD0576  [5]
 LDCM0260  AC140 HCT 116 C108(1.53); C84(1.35)  LDD0577  [5]
 LDCM0261  AC141 HCT 116 C108(1.63); C84(1.17)  LDD0578  [5]
 LDCM0262  AC142 HCT 116 C108(1.76); C84(1.12)  LDD0579  [5]
 LDCM0263  AC143 HCT 116 C108(0.92); C84(1.10); C92(1.03)  LDD0580  [5]
 LDCM0264  AC144 HCT 116 C92(1.06); C108(1.26); C84(1.27)  LDD0581  [5]
 LDCM0265  AC145 HCT 116 C92(0.95); C108(1.12); C84(1.16)  LDD0582  [5]
 LDCM0266  AC146 HCT 116 C92(0.76); C108(1.00); C84(1.21)  LDD0583  [5]
 LDCM0267  AC147 HCT 116 C84(1.09); C108(1.13); C92(1.23)  LDD0584  [5]
 LDCM0268  AC148 HCT 116 C92(0.90); C108(1.38); C84(1.57)  LDD0585  [5]
 LDCM0269  AC149 HCT 116 C92(0.86); C108(1.16); C84(1.24)  LDD0586  [5]
 LDCM0270  AC15 HCT 116 C108(1.07); C92(1.14); C84(1.20)  LDD0587  [5]
 LDCM0271  AC150 HCT 116 C92(0.94); C84(1.06); C108(1.32)  LDD0588  [5]
 LDCM0272  AC151 HCT 116 C92(0.93); C84(1.15); C108(1.78)  LDD0589  [5]
 LDCM0273  AC152 HCT 116 C92(0.94); C108(1.03); C84(1.30)  LDD0590  [5]
 LDCM0274  AC153 HCT 116 C92(0.89); C108(1.47); C84(1.52)  LDD0591  [5]
 LDCM0621  AC154 HCT 116 C108(1.11); C84(1.23); C92(1.01)  LDD2158  [5]
 LDCM0622  AC155 HCT 116 C108(1.45); C84(1.13); C92(0.88)  LDD2159  [5]
 LDCM0623  AC156 HCT 116 C108(0.90); C84(0.90); C92(0.91)  LDD2160  [5]
 LDCM0624  AC157 HCT 116 C108(0.83); C84(0.85); C92(0.98)  LDD2161  [5]
 LDCM0276  AC17 HCT 116 C84(1.06); C108(1.19)  LDD0593  [5]
 LDCM0277  AC18 HCT 116 C84(0.87); C108(1.28)  LDD0594  [5]
 LDCM0278  AC19 HCT 116 C84(1.08); C108(1.11)  LDD0595  [5]
 LDCM0279  AC2 HCT 116 C92(1.06); C108(1.12); C84(1.16)  LDD0596  [5]
 LDCM0280  AC20 HCT 116 C84(0.98); C108(1.16)  LDD0597  [5]
 LDCM0281  AC21 HCT 116 C84(0.94); C108(1.06)  LDD0598  [5]
 LDCM0282  AC22 HCT 116 C84(0.92); C108(1.08)  LDD0599  [5]
 LDCM0283  AC23 HCT 116 C84(0.98); C108(1.08)  LDD0600  [5]
 LDCM0284  AC24 HCT 116 C84(0.93); C108(1.08)  LDD0601  [5]
 LDCM0285  AC25 HCT 116 C84(1.14); C108(1.15); C92(1.15)  LDD0602  [5]
 LDCM0286  AC26 HCT 116 C108(1.21); C84(1.21); C92(1.23)  LDD0603  [5]
 LDCM0287  AC27 HCT 116 C92(1.15); C108(1.17); C84(1.30)  LDD0604  [5]
 LDCM0288  AC28 HCT 116 C84(1.15); C108(1.16); C92(1.24)  LDD0605  [5]
 LDCM0289  AC29 HCT 116 C92(0.83); C84(1.28); C108(1.29)  LDD0606  [5]
 LDCM0290  AC3 HCT 116 C108(1.12); C84(1.19); C92(1.24)  LDD0607  [5]
 LDCM0291  AC30 HCT 116 C92(0.86); C108(1.25); C84(1.27)  LDD0608  [5]
 LDCM0292  AC31 HCT 116 C92(1.17); C108(1.23); C84(1.27)  LDD0609  [5]
 LDCM0293  AC32 HCT 116 C92(0.94); C108(1.34); C84(1.48)  LDD0610  [5]
 LDCM0294  AC33 HCT 116 C92(1.05); C108(1.24); C84(1.40)  LDD0611  [5]
 LDCM0295  AC34 HCT 116 C92(1.13); C84(1.37); C108(1.45)  LDD0612  [5]
 LDCM0296  AC35 HCT 116 C108(0.86); C84(0.86)  LDD0613  [5]
 LDCM0297  AC36 HCT 116 C108(0.92); C84(1.29)  LDD0614  [5]
 LDCM0298  AC37 HCT 116 C108(0.97); C84(1.01)  LDD0615  [5]
 LDCM0299  AC38 HCT 116 C108(0.96); C84(1.07)  LDD0616  [5]
 LDCM0300  AC39 HCT 116 C108(1.07); C84(1.15)  LDD0617  [5]
 LDCM0301  AC4 HCT 116 C108(1.04); C84(1.15); C92(1.56)  LDD0618  [5]
 LDCM0302  AC40 HCT 116 C108(1.05); C84(1.11)  LDD0619  [5]
 LDCM0303  AC41 HCT 116 C108(1.04); C84(1.24)  LDD0620  [5]
 LDCM0304  AC42 HCT 116 C108(1.05); C84(1.09)  LDD0621  [5]
 LDCM0305  AC43 HCT 116 C108(1.03); C84(1.25)  LDD0622  [5]
 LDCM0306  AC44 HCT 116 C108(1.00); C84(1.06)  LDD0623  [5]
 LDCM0307  AC45 HCT 116 C84(1.12); C108(1.16)  LDD0624  [5]
 LDCM0308  AC46 HCT 116 C92(0.63); C108(1.10); C84(1.51)  LDD0625  [5]
 LDCM0309  AC47 HCT 116 C92(0.86); C108(1.06); C84(1.41)  LDD0626  [5]
 LDCM0310  AC48 HCT 116 C92(0.64); C108(1.11); C84(1.48)  LDD0627  [5]
 LDCM0311  AC49 HCT 116 C92(0.58); C108(1.18); C84(1.43)  LDD0628  [5]
 LDCM0312  AC5 HCT 116 C108(1.06); C84(1.32); C92(1.60)  LDD0629  [5]
 LDCM0313  AC50 HCT 116 C92(0.57); C108(1.11); C84(1.45)  LDD0630  [5]
 LDCM0314  AC51 HCT 116 C92(0.63); C108(0.94); C84(0.96)  LDD0631  [5]
 LDCM0315  AC52 HCT 116 C92(0.62); C108(1.04); C84(1.34)  LDD0632  [5]
 LDCM0316  AC53 HCT 116 C92(0.91); C108(0.96); C84(1.18)  LDD0633  [5]
 LDCM0317  AC54 HCT 116 C92(0.71); C108(1.04); C84(1.44)  LDD0634  [5]
 LDCM0318  AC55 HCT 116 C108(1.00); C84(1.22); C92(1.42)  LDD0635  [5]
 LDCM0319  AC56 HCT 116 C92(0.81); C108(0.95); C84(1.65)  LDD0636  [5]
 LDCM0320  AC57 HCT 116 C92(1.02); C84(1.28); C108(1.47)  LDD0637  [5]
 LDCM0321  AC58 HCT 116 C92(1.01); C108(1.41); C84(1.41)  LDD0638  [5]
 LDCM0322  AC59 HCT 116 C92(1.03); C108(1.57); C84(1.69)  LDD0639  [5]
 LDCM0323  AC6 HCT 116 C92(0.79); C108(1.06); C84(1.24)  LDD0640  [5]
 LDCM0324  AC60 HCT 116 C92(0.81); C108(1.33); C84(1.51)  LDD0641  [5]
 LDCM0325  AC61 HCT 116 C92(0.86); C84(1.27); C108(1.35)  LDD0642  [5]
 LDCM0326  AC62 HCT 116 C92(0.94); C84(1.25); C108(1.53)  LDD0643  [5]
 LDCM0327  AC63 HCT 116 C92(0.99); C108(1.51); C84(1.53)  LDD0644  [5]
 LDCM0328  AC64 HCT 116 C92(0.92); C84(1.61); C108(1.67)  LDD0645  [5]
 LDCM0329  AC65 HCT 116 C92(1.05); C84(1.54); C108(1.83)  LDD0646  [5]
 LDCM0330  AC66 HCT 116 C92(1.10); C108(1.58); C84(1.59)  LDD0647  [5]
 LDCM0331  AC67 HCT 116 C92(0.90); C84(1.67); C108(1.90)  LDD0648  [5]
 LDCM0332  AC68 HCT 116 C92(0.81); C84(1.06); C108(1.16)  LDD0649  [5]
 LDCM0333  AC69 HCT 116 C92(0.85); C108(0.95); C84(1.03)  LDD0650  [5]
 LDCM0334  AC7 HCT 116 C92(0.87); C108(1.11); C84(1.17)  LDD0651  [5]
 LDCM0335  AC70 HCT 116 C92(0.68); C84(1.05); C108(1.19)  LDD0652  [5]
 LDCM0336  AC71 HCT 116 C92(0.89); C108(1.00); C84(1.21)  LDD0653  [5]
 LDCM0337  AC72 HCT 116 C92(0.77); C108(1.10); C84(1.21)  LDD0654  [5]
 LDCM0338  AC73 HCT 116 C92(0.67); C108(1.32); C84(1.35)  LDD0655  [5]
 LDCM0339  AC74 HCT 116 C92(1.15); C108(1.23); C84(1.82)  LDD0656  [5]
 LDCM0340  AC75 HCT 116 C92(0.81); C84(1.33); C108(1.42)  LDD0657  [5]
 LDCM0341  AC76 HCT 116 C92(1.05); C108(1.10); C84(1.14)  LDD0658  [5]
 LDCM0342  AC77 HCT 116 C92(0.74); C108(1.06); C84(1.37)  LDD0659  [5]
 LDCM0343  AC78 HCT 116 C92(0.69); C108(0.98); C84(1.19)  LDD0660  [5]
 LDCM0344  AC79 HCT 116 C92(0.70); C108(1.14); C84(1.22)  LDD0661  [5]
 LDCM0345  AC8 HCT 116 C92(0.90); C84(0.99); C108(1.19)  LDD0662  [5]
 LDCM0346  AC80 HCT 116 C108(1.11); C92(1.13); C84(1.31)  LDD0663  [5]
 LDCM0347  AC81 HCT 116 C92(0.82); C108(1.08); C84(1.18)  LDD0664  [5]
 LDCM0348  AC82 HCT 116 C92(1.05); C84(1.32); C108(1.47)  LDD0665  [5]
 LDCM0349  AC83 HCT 116 C84(1.27); C108(1.29)  LDD0666  [5]
 LDCM0350  AC84 HCT 116 C84(1.36); C108(1.41)  LDD0667  [5]
 LDCM0351  AC85 HCT 116 C84(1.09); C108(1.11)  LDD0668  [5]
 LDCM0352  AC86 HCT 116 C108(1.17); C84(1.28)  LDD0669  [5]
 LDCM0353  AC87 HCT 116 C108(1.05); C84(1.08)  LDD0670  [5]
 LDCM0354  AC88 HCT 116 C84(1.08); C108(1.12)  LDD0671  [5]
 LDCM0355  AC89 HCT 116 C108(1.20); C84(1.23)  LDD0672  [5]
 LDCM0357  AC90 HCT 116 C108(1.01); C84(1.04)  LDD0674  [5]
 LDCM0358  AC91 HCT 116 C108(1.23); C84(1.41)  LDD0675  [5]
 LDCM0359  AC92 HCT 116 C108(1.23); C84(1.43)  LDD0676  [5]
 LDCM0360  AC93 HCT 116 C84(0.96); C108(1.16)  LDD0677  [5]
 LDCM0361  AC94 HCT 116 C84(0.94); C108(1.07)  LDD0678  [5]
 LDCM0362  AC95 HCT 116 C108(1.09); C84(1.14)  LDD0679  [5]
 LDCM0363  AC96 HCT 116 C108(1.12); C84(1.32)  LDD0680  [5]
 LDCM0364  AC97 HCT 116 C84(1.09); C108(1.20)  LDD0681  [5]
 LDCM0365  AC98 HCT 116 C84(1.32); C108(1.37)  LDD0682  [5]
 LDCM0366  AC99 HCT 116 C84(0.94); C108(1.14)  LDD0683  [5]
 LDCM0248  AKOS034007472 HCT 116 C108(1.23); C84(1.19); C92(1.29)  LDD0565  [5]
 LDCM0356  AKOS034007680 HCT 116 C108(1.07); C84(1.22); C92(1.25)  LDD0673  [5]
 LDCM0275  AKOS034007705 HCT 116 C92(0.86); C108(1.18); C84(1.63)  LDD0592  [5]
 LDCM0156  Aniline NCI-H1299 11.74  LDD0403  [2]
 LDCM0020  ARS-1620 HCC44 C84(1.14); C108(0.99)  LDD0078  [5]
 LDCM0630  CCW28-3 231MFP C84(0.25)  LDD2214  [18]
 LDCM0108  Chloroacetamide HeLa C280(0.00); C108(0.00)  LDD0222  [10]
 LDCM0632  CL-Sc Hep-G2 C108(20.00); C280(1.76); C108(0.42)  LDD2227  [13]
 LDCM0367  CL1 HCT 116 C84(0.93); C92(0.95); C108(1.03)  LDD0684  [5]
 LDCM0368  CL10 HCT 116 C92(0.75); C108(1.05); C84(1.28)  LDD0685  [5]
 LDCM0369  CL100 HCT 116 C84(1.03); C108(1.08); C92(1.27)  LDD0686  [5]
 LDCM0370  CL101 HCT 116 C92(0.91); C108(1.02); C84(1.28)  LDD0687  [5]
 LDCM0371  CL102 HCT 116 C92(0.86); C108(0.89); C84(1.21)  LDD0688  [5]
 LDCM0372  CL103 HCT 116 C108(0.94); C84(1.00); C92(1.23)  LDD0689  [5]
 LDCM0373  CL104 HCT 116 C92(0.91); C108(1.03); C84(1.04)  LDD0690  [5]
 LDCM0374  CL105 HCT 116 C84(1.15); C108(1.24)  LDD0691  [5]
 LDCM0375  CL106 HCT 116 C84(1.29); C108(1.29)  LDD0692  [5]
 LDCM0376  CL107 HCT 116 C84(1.26); C108(1.27)  LDD0693  [5]
 LDCM0377  CL108 HCT 116 C84(1.19); C108(1.41)  LDD0694  [5]
 LDCM0378  CL109 HCT 116 C84(1.11); C108(1.15)  LDD0695  [5]
 LDCM0379  CL11 HCT 116 C108(0.81); C92(0.97); C84(1.24)  LDD0696  [5]
 LDCM0380  CL110 HCT 116 C84(1.16); C108(1.20)  LDD0697  [5]
 LDCM0381  CL111 HCT 116 C84(1.03); C108(1.12)  LDD0698  [5]
 LDCM0382  CL112 HCT 116 C84(0.91); C108(0.99); C92(1.09)  LDD0699  [5]
 LDCM0383  CL113 HCT 116 C92(0.88); C84(1.19); C108(1.38)  LDD0700  [5]
 LDCM0384  CL114 HCT 116 C92(0.87); C84(1.14); C108(1.25)  LDD0701  [5]
 LDCM0385  CL115 HCT 116 C84(1.09); C92(1.13); C108(1.23)  LDD0702  [5]
 LDCM0386  CL116 HCT 116 C108(1.20); C84(1.31); C92(1.36)  LDD0703  [5]
 LDCM0387  CL117 HCT 116 C108(1.22); C84(1.27)  LDD0704  [5]
 LDCM0388  CL118 HCT 116 C108(1.09); C84(1.15)  LDD0705  [5]
 LDCM0389  CL119 HCT 116 C84(1.07); C108(1.12)  LDD0706  [5]
 LDCM0390  CL12 HCT 116 C92(0.80); C108(1.00); C84(1.37)  LDD0707  [5]
 LDCM0391  CL120 HCT 116 C108(1.10); C84(1.13)  LDD0708  [5]
 LDCM0392  CL121 HCT 116 C92(0.73); C108(0.86); C84(1.10)  LDD0709  [5]
 LDCM0393  CL122 HCT 116 C92(0.71); C108(0.89); C84(1.53)  LDD0710  [5]
 LDCM0394  CL123 HCT 116 C108(0.48); C92(0.67); C84(1.53)  LDD0711  [5]
 LDCM0395  CL124 HCT 116 C92(0.66); C108(1.10); C84(1.73)  LDD0712  [5]
 LDCM0396  CL125 HCT 116 C84(1.09); C92(1.16); C108(1.23)  LDD0713  [5]
 LDCM0397  CL126 HCT 116 C92(0.77); C108(1.17); C84(1.54)  LDD0714  [5]
 LDCM0398  CL127 HCT 116 C108(1.18); C84(1.22); C92(1.29)  LDD0715  [5]
 LDCM0399  CL128 HCT 116 C92(1.04); C84(1.31); C108(1.43)  LDD0716  [5]
 LDCM0400  CL13 HCT 116 C92(0.80); C108(0.97); C84(1.28)  LDD0717  [5]
 LDCM0401  CL14 HCT 116 C92(0.82); C108(0.97); C84(1.12)  LDD0718  [5]
 LDCM0402  CL15 HCT 116 C92(0.92); C108(0.96); C84(1.27)  LDD0719  [5]
 LDCM0403  CL16 HCT 116 C92(1.05); C84(1.07); C108(1.40)  LDD0720  [5]
 LDCM0404  CL17 HCT 116 C92(0.97); C108(0.99); C84(1.01)  LDD0721  [5]
 LDCM0405  CL18 HCT 116 C92(0.94); C84(1.11); C108(1.24)  LDD0722  [5]
 LDCM0406  CL19 HCT 116 C92(0.81); C108(1.05); C84(1.21)  LDD0723  [5]
 LDCM0407  CL2 HCT 116 C92(0.86); C84(0.97); C108(1.08)  LDD0724  [5]
 LDCM0408  CL20 HCT 116 C92(0.99); C108(1.24); C84(1.42)  LDD0725  [5]
 LDCM0409  CL21 HCT 116 C92(0.87); C108(1.22); C84(1.26)  LDD0726  [5]
 LDCM0410  CL22 HCT 116 C92(1.14); C108(1.26); C84(1.52)  LDD0727  [5]
 LDCM0411  CL23 HCT 116 C92(0.90); C108(1.12); C84(1.15)  LDD0728  [5]
 LDCM0412  CL24 HCT 116 C92(0.98); C84(1.13); C108(1.62)  LDD0729  [5]
 LDCM0413  CL25 HCT 116 C108(1.29); C84(1.39); C92(0.70)  LDD0730  [5]
 LDCM0414  CL26 HCT 116 C108(1.47); C84(1.17); C92(0.94)  LDD0731  [5]
 LDCM0415  CL27 HCT 116 C108(1.41); C84(1.20); C92(0.91)  LDD0732  [5]
 LDCM0416  CL28 HCT 116 C108(1.78); C84(1.13); C92(0.94)  LDD0733  [5]
 LDCM0417  CL29 HCT 116 C108(1.22); C84(1.21); C92(0.89)  LDD0734  [5]
 LDCM0418  CL3 HCT 116 C108(0.87); C84(0.90); C92(0.82)  LDD0735  [5]
 LDCM0419  CL30 HCT 116 C108(1.61); C84(1.30); C92(0.92)  LDD0736  [5]
 LDCM0420  CL31 HCT 116 C108(0.97); C84(1.11)  LDD0737  [5]
 LDCM0421  CL32 HCT 116 C108(1.18); C84(1.16)  LDD0738  [5]
 LDCM0422  CL33 HCT 116 C108(1.13); C84(1.51)  LDD0739  [5]
 LDCM0423  CL34 HCT 116 C108(0.94); C84(1.35)  LDD0740  [5]
 LDCM0424  CL35 HCT 116 C108(1.49); C84(1.27)  LDD0741  [5]
 LDCM0425  CL36 HCT 116 C108(0.92); C84(1.29)  LDD0742  [5]
 LDCM0426  CL37 HCT 116 C108(1.15); C84(1.26)  LDD0743  [5]
 LDCM0428  CL39 HCT 116 C108(1.14); C84(1.29)  LDD0745  [5]
 LDCM0429  CL4 HCT 116 C108(0.98); C84(1.09); C92(1.04)  LDD0746  [5]
 LDCM0430  CL40 HCT 116 C108(1.02); C84(1.22)  LDD0747  [5]
 LDCM0431  CL41 HCT 116 C108(0.81); C84(1.20)  LDD0748  [5]
 LDCM0432  CL42 HCT 116 C108(0.75); C84(1.52)  LDD0749  [5]
 LDCM0433  CL43 HCT 116 C108(1.08); C84(1.34)  LDD0750  [5]
 LDCM0434  CL44 HCT 116 C108(1.33); C84(1.23)  LDD0751  [5]
 LDCM0435  CL45 HCT 116 C108(1.30); C84(1.40)  LDD0752  [5]
 LDCM0436  CL46 HCT 116 C108(0.94); C84(0.81)  LDD0753  [5]
 LDCM0437  CL47 HCT 116 C108(0.98); C84(0.65)  LDD0754  [5]
 LDCM0438  CL48 HCT 116 C108(0.94); C84(0.65)  LDD0755  [5]
 LDCM0439  CL49 HCT 116 C108(0.96); C84(0.76)  LDD0756  [5]
 LDCM0440  CL5 HCT 116 C108(1.01); C84(1.12); C92(0.88)  LDD0757  [5]
 LDCM0441  CL50 HCT 116 C108(0.93); C84(0.71)  LDD0758  [5]
 LDCM0442  CL51 HCT 116 C108(0.99); C84(0.81)  LDD0759  [5]
 LDCM0443  CL52 HCT 116 C108(1.05); C84(0.73)  LDD0760  [5]
 LDCM0444  CL53 HCT 116 C108(0.87); C84(0.62)  LDD0761  [5]
 LDCM0445  CL54 HCT 116 C108(0.91); C84(0.72)  LDD0762  [5]
 LDCM0446  CL55 HCT 116 C108(0.94); C84(0.71)  LDD0763  [5]
 LDCM0447  CL56 HCT 116 C108(1.01); C84(0.85)  LDD0764  [5]
 LDCM0448  CL57 HCT 116 C108(0.94); C84(0.66)  LDD0765  [5]
 LDCM0449  CL58 HCT 116 C108(0.96); C84(0.68)  LDD0766  [5]
 LDCM0450  CL59 HCT 116 C108(1.00); C84(0.78)  LDD0767  [5]
 LDCM0451  CL6 HCT 116 C108(1.12); C84(1.06); C92(0.74)  LDD0768  [5]
 LDCM0452  CL60 HCT 116 C108(1.06); C84(0.79)  LDD0769  [5]
 LDCM0453  CL61 HCT 116 C108(1.04); C84(1.11); C92(0.70)  LDD0770  [5]
 LDCM0454  CL62 HCT 116 C108(0.88); C84(1.08); C92(0.79)  LDD0771  [5]
 LDCM0455  CL63 HCT 116 C108(0.83); C84(1.11); C92(0.76)  LDD0772  [5]
 LDCM0456  CL64 HCT 116 C108(1.01); C84(1.31); C92(0.91)  LDD0773  [5]
 LDCM0457  CL65 HCT 116 C108(1.03); C84(1.05); C92(0.86)  LDD0774  [5]
 LDCM0458  CL66 HCT 116 C108(1.03); C84(1.42); C92(0.94)  LDD0775  [5]
 LDCM0459  CL67 HCT 116 C108(0.84); C84(1.21); C92(0.93)  LDD0776  [5]
 LDCM0460  CL68 HCT 116 C108(0.80); C84(1.21); C92(0.70)  LDD0777  [5]
 LDCM0461  CL69 HCT 116 C108(0.97); C84(1.13); C92(0.55)  LDD0778  [5]
 LDCM0462  CL7 HCT 116 C108(1.07); C84(1.22); C92(0.91)  LDD0779  [5]
 LDCM0463  CL70 HCT 116 C108(0.89); C84(1.15); C92(0.65)  LDD0780  [5]
 LDCM0464  CL71 HCT 116 C108(1.00); C84(1.20); C92(0.58)  LDD0781  [5]
 LDCM0465  CL72 HCT 116 C108(0.98); C84(1.12); C92(0.56)  LDD0782  [5]
 LDCM0466  CL73 HCT 116 C108(0.95); C84(1.21); C92(0.78)  LDD0783  [5]
 LDCM0467  CL74 HCT 116 C108(0.82); C84(1.20); C92(0.73)  LDD0784  [5]
 LDCM0469  CL76 HCT 116 C108(0.94); C84(1.03)  LDD0786  [5]
 LDCM0470  CL77 HCT 116 C108(0.81); C84(0.95)  LDD0787  [5]
 LDCM0471  CL78 HCT 116 C108(0.98); C84(1.02)  LDD0788  [5]
 LDCM0472  CL79 HCT 116 C108(1.01); C84(1.20)  LDD0789  [5]
 LDCM0473  CL8 HCT 116 C108(0.93); C84(1.37); C92(0.59)  LDD0790  [5]
 LDCM0474  CL80 HCT 116 C108(1.02); C84(1.12)  LDD0791  [5]
 LDCM0475  CL81 HCT 116 C108(0.96); C84(1.12)  LDD0792  [5]
 LDCM0476  CL82 HCT 116 C108(1.03); C84(1.42)  LDD0793  [5]
 LDCM0477  CL83 HCT 116 C108(0.89); C84(1.39)  LDD0794  [5]
 LDCM0478  CL84 HCT 116 C108(1.03); C84(1.45)  LDD0795  [5]
 LDCM0479  CL85 HCT 116 C108(1.03); C84(1.23)  LDD0796  [5]
 LDCM0480  CL86 HCT 116 C108(0.98); C84(1.02)  LDD0797  [5]
 LDCM0481  CL87 HCT 116 C108(0.95); C84(1.28)  LDD0798  [5]
 LDCM0482  CL88 HCT 116 C108(0.89); C84(1.26)  LDD0799  [5]
 LDCM0483  CL89 HCT 116 C108(0.86); C84(1.73)  LDD0800  [5]
 LDCM0484  CL9 HCT 116 C108(1.07); C84(1.18); C92(0.77)  LDD0801  [5]
 LDCM0485  CL90 HCT 116 C108(0.82); C84(1.17)  LDD0802  [5]
 LDCM0486  CL91 HCT 116 C108(1.11); C84(1.11); C92(0.86)  LDD0803  [5]
 LDCM0487  CL92 HCT 116 C108(0.97); C84(1.11); C92(1.05)  LDD0804  [5]
 LDCM0488  CL93 HCT 116 C108(1.05); C84(1.01); C92(1.38)  LDD0805  [5]
 LDCM0489  CL94 HCT 116 C108(0.89); C84(1.15); C92(2.09)  LDD0806  [5]
 LDCM0490  CL95 HCT 116 C108(0.97); C84(1.14); C92(1.11)  LDD0807  [5]
 LDCM0491  CL96 HCT 116 C108(1.05); C84(1.18); C92(1.03)  LDD0808  [5]
 LDCM0492  CL97 HCT 116 C108(1.16); C84(1.23); C92(0.99)  LDD0809  [5]
 LDCM0493  CL98 HCT 116 C108(1.09); C84(1.10); C92(1.02)  LDD0810  [5]
 LDCM0494  CL99 HCT 116 C108(1.03); C84(1.10); C92(1.18)  LDD0811  [5]
 LDCM0634  CY-0357 Hep-G2 C108(0.78)  LDD2228  [13]
 LDCM0495  E2913 HEK-293T C108(1.12); C84(1.00); C92(0.98); C280(0.97)  LDD1698  [19]
 LDCM0625  F8 Ramos C108(1.36); C280(1.05); C84(1.35)  LDD2187  [20]
 LDCM0572  Fragment10 Ramos C108(1.13)  LDD2189  [20]
 LDCM0573  Fragment11 Ramos C108(0.90); C280(0.73); C84(0.55)  LDD2190  [20]
 LDCM0574  Fragment12 Ramos C108(1.07)  LDD2191  [20]
 LDCM0575  Fragment13 Ramos C108(1.06)  LDD2192  [20]
 LDCM0576  Fragment14 Ramos C108(0.69); C280(0.76); C84(1.27)  LDD2193  [20]
 LDCM0579  Fragment20 Ramos C108(0.98)  LDD2194  [20]
 LDCM0580  Fragment21 Ramos C108(0.78)  LDD2195  [20]
 LDCM0582  Fragment23 Ramos C108(0.79)  LDD2196  [20]
 LDCM0578  Fragment27 Ramos C108(0.99)  LDD2197  [20]
 LDCM0586  Fragment28 Ramos C108(0.87); C280(0.68)  LDD2198  [20]
 LDCM0588  Fragment30 Ramos C108(1.15)  LDD2199  [20]
 LDCM0589  Fragment31 Ramos C108(1.10)  LDD2200  [20]
 LDCM0590  Fragment32 Ramos C108(1.56)  LDD2201  [20]
 LDCM0468  Fragment33 HCT 116 C108(0.92); C84(1.31); C92(0.61)  LDD0785  [5]
 LDCM0596  Fragment38 Ramos C108(0.97)  LDD2203  [20]
 LDCM0566  Fragment4 Ramos C108(1.03); C280(0.94); C84(0.60)  LDD2184  [20]
 LDCM0427  Fragment51 HCT 116 C108(1.11); C84(1.51)  LDD0744  [5]
 LDCM0610  Fragment52 Ramos C108(0.95)  LDD2204  [20]
 LDCM0614  Fragment56 Ramos C108(1.11)  LDD2205  [20]
 LDCM0569  Fragment7 Ramos C108(0.84); C280(0.70); C84(0.66)  LDD2186  [20]
 LDCM0571  Fragment9 Ramos C108(1.11)  LDD2188  [20]
 LDCM0107  IAA HeLa N.A.  LDD0221  [10]
 LDCM0022  KB02 HCT 116 C84(1.06)  LDD0080  [5]
 LDCM0023  KB03 HCT 116 C84(2.23)  LDD0081  [5]
 LDCM0024  KB05 HCT 116 C84(1.79)  LDD0082  [5]
 LDCM0109  NEM HeLa N.A.  LDD0223  [10]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C108(1.04)  LDD2093  [4]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C108(0.87)  LDD2096  [4]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C108(1.03)  LDD2099  [4]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C108(1.04)  LDD2109  [4]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C108(1.40)  LDD2111  [4]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C108(0.77)  LDD2123  [4]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C108(0.91)  LDD2125  [4]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C108(1.38)  LDD2127  [4]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C108(1.20)  LDD2129  [4]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C108(1.13)  LDD2135  [4]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C108(1.93)  LDD2136  [4]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C108(1.01)  LDD2137  [4]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C108(0.94)  LDD2140  [4]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C108(0.94)  LDD2146  [4]
 LDCM0627  NUDT7-COV-1 HEK-293T C108(2.99)  LDD2206  [21]
 LDCM0131  RA190 MM1.R C84(1.25)  LDD0304  [22]
 LDCM0090  Rapamycin JHH-7 4.67  LDD0213  [16]
 LDCM0096  SAHA K562 4.50  LDD0360  [3]
 LDCM0021  THZ1 HCT 116 C108(1.21); C84(1.07)  LDD2173  [5]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (GCNT1) Glycosyltransferase 14 family Q02742
X-ray repair cross-complementing protein 5 (XRCC5) Ku80 family P13010
Unconventional myosin-XVIIIa (MYO18A) Myosin family Q92614
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) ARL6ip family Q15041

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
3 Streamlined Target Deconvolution Approach Utilizing a Single Photoreactive Chloroalkane Capture Tag. ACS Chem Biol. 2021 Feb 19;16(2):404-413. doi: 10.1021/acschembio.0c00987. Epub 2021 Feb 5.
4 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
5 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
6 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
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Mass spectrometry data entry: PXD028853
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Mass spectrometry data entry: PXD029255
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Mass spectrometry data entry: PXD033004
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD044402
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Mass spectrometry data entry: PXD027578
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