Details of the Probe

General Information of Probe

Probe ID
LDPC0479
Probe Name
C246
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 327.815
Lipid-water partition coefficient (xlogp) 3.45
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C18H18ClN3O
Canonical SMILES
[H]C#CC([H])([H])C([H])([H])C1(C([H])([H])C([H])([H])C(=O)N([H])C2([H])C3([H])c4c([H])c([H])c(Cl)c([H])c4C([H])([H])C32[H])N=N1
InChI
InChI=1S/C18H18ClN3O/c1-2-3-7-18(21-22-18)8-6-15(23)20-17-14-10-11-9-12(19)4-5-13(11)16(14)17/h1,4-5,9,14,16-17H,3,6-8,10H2,(H,20,23)/t14-,16+,17+/m0/s1
InChIKey
LGKWSGMONMTSKB-USXIJHARSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

142 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 23.75  LDD1919 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 14.22  LDD1919 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 23.75  LDD1919 
Acid ceramidase (ASAH1) LDTP05905 33.82  LDD1919 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 12.82  LDD1919 
ADP-dependent glucokinase (ADPGK) LDTP11127 16.22  LDD1919 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 35.02  LDD1919 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 37.79  LDD1919 
Antigen peptide transporter 1 (TAP1) LDTP05408 25.99  LDD1919 
Atlastin-2 (ATL2) LDTP09251 17.75  LDD1919 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 42.22  LDD1919 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 14.32  LDD1919 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 13.18  LDD1919 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 13.00  LDD1919 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 13.27  LDD1919 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 39.95  LDD1919 
Calcium-independent phospholipase A2-gamma (PNPLA8) LDTP12318 13.00  LDD1919 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 25.28  LDD1919 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 15.45  LDD1919 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 15.14  LDD1919 
Catechol O-methyltransferase (COMT) LDTP03145 24.76  LDD1919 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 39.95  LDD1919 
Ceramide synthase 2 (CERS2) LDTP10329 21.86  LDD1919 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 16.45  LDD1919 
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (ST3GAL4) LDTP05638 18.90  LDD1919 
COP9 signalosome complex subunit 3 (COPS3) LDTP13675 12.38  LDD1919 
Copper-transporting ATPase 2 (ATP7B) LDTP03779 16.45  LDD1919 
CTP synthase 1 (CTPS1) LDTP02922 28.64  LDD1919 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 17.51  LDD1919 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 50.21  LDD1919 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 45.57  LDD1919 
Cytochrome b5 type B (CYB5B) LDTP00697 99.73  LDD1919 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 25.63  LDD1919 
Cytosolic 5'-nucleotidase 3A (NT5C3A) LDTP11723 12.30  LDD1919 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 23.43  LDD1919 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 20.97  LDD1919 
Delta(14)-sterol reductase TM7SF2 (TM7SF2) LDTP01389 21.71  LDD1919 
Delta(24)-sterol reductase (DHCR24) LDTP06375 24.59  LDD1919 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 16.68  LDD1919 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 13.09  LDD1919 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 28.25  LDD1919 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 18.38  LDD1919 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 51.98  LDD1919 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 13.83  LDD1919 
E3 ubiquitin-protein ligase TRIM13 (TRIM13) LDTP01065 25.81  LDD1919 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 14.32  LDD1919 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 14.42  LDD1919 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 17.15  LDD1919 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 15.45  LDD1919 
Epoxide hydrolase 1 (EPHX1) LDTP02175 25.63  LDD1919 
Ferrochelatase, mitochondrial (FECH) LDTP03198 12.47  LDD1919 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 14.03  LDD1919 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 12.30  LDD1919 
GPI-anchor transamidase (PIGK) LDTP09835 13.09  LDD1919 
GTP-binding protein SAR1a (SAR1A) LDTP12470 12.30  LDD1919 
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) LDTP13352 17.51  LDD1919 
Heme A synthase COX15 (COX15) LDTP07931 16.34  LDD1919 
Heme oxygenase 1 (HMOX1) LDTP02359 40.79  LDD1919 
Heme oxygenase 2 (HMOX2) LDTP03540 30.06  LDD1919 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 16.34  LDD1919 
Hexokinase-2 (HK2) LDTP04531 18.77  LDD1919 
Holocytochrome c-type synthase (HCCS) LDTP04581 16.68  LDD1919 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 38.85  LDD1919 
Integrator complex subunit 11 (INTS11) LDTP07158 12.38  LDD1919 
Isochorismatase domain-containing protein 1 (ISOC1) LDTP19851 13.93  LDD1919 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 23.92  LDD1919 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 18.64  LDD1919 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 22.94  LDD1919 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 13.27  LDD1919 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 15.67  LDD1919 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 15.78  LDD1919 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 21.71  LDD1919 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 18.38  LDD1919 
Lysosomal acid phosphatase (ACP2) LDTP02539 14.93  LDD1919 
Lysosomal protective protein (CTSA) LDTP02505 16.22  LDD1919 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 15.03  LDD1919 
Medium-chain acyl-CoA ligase ACSF2, mitochondrial (ACSF2) LDTP10177 19.29  LDD1919 
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) LDTP10930 17.39  LDD1919 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 14.52  LDD1919 
Minor histocompatibility antigen H13 (HM13) LDTP09396 12.21  LDD1919 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 14.22  LDD1919 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 16.45  LDD1919 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 25.46  LDD1919 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 27.86  LDD1919 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 14.62  LDD1919 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 33.82  LDD1919 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 16.91  LDD1919 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 54.57  LDD1919 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 28.84  LDD1919 
NADH dehydrogenase 1 subunit C2 (NDUFC2) LDTP01560 17.03  LDD1919 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 29.24  LDD1919 
NADPH--cytochrome P450 reductase (POR) LDTP02848 12.73  LDD1919 
Neutral cholesterol ester hydrolase 1 (NCEH1) LDTP07591 13.18  LDD1919 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 41.64  LDD1919 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 44.63  LDD1919 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 18.77  LDD1919 
Palmitoyltransferase ZDHHC13 (ZDHHC13) LDTP08455 22.16  LDD1919 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 13.93  LDD1919 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 14.83  LDD1919 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 35.51  LDD1919 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 19.84  LDD1919 
Phosphatidylinositol 4-kinase type 2-alpha (PI4K2A) LDTP11209 12.38  LDD1919 
Pirin (PIR) LDTP00325 36.50  LDD1919 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 14.32  LDD1919 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 31.12  LDD1919 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 22.16  LDD1919 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 12.82  LDD1919 
Prostaglandin reductase 3 (PTGR3) LDTP15422 21.86  LDD1919 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 26.17  LDD1919 
Protein-L-histidine N-pros-methyltransferase (METTL9) LDTP15962 14.93  LDD1919 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 26.91  LDD1919 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 12.73  LDD1919 
Rab-like protein 3 (RABL3) LDTP06986 29.65  LDD1919 
Ras-related protein Rab-24 (RAB24) LDTP10020 19.03  LDD1919 
Ras-related protein Rab-32 (RAB32) LDTP05958 13.93  LDD1919 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 18.13  LDD1919 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 14.83  LDD1919 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 12.91  LDD1919 
Retinol dehydrogenase 13 (RDH13) LDTP09061 17.63  LDD1919 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 13.74  LDD1919 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 17.88  LDD1919 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 29.45  LDD1919 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 14.83  LDD1919 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 15.14  LDD1919 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 18.77  LDD1919 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 20.68  LDD1919 
Squalene monooxygenase (SQLE) LDTP06142 16.34  LDD1919 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 16.00  LDD1919 
Sulfhydryl oxidase 2 (QSOX2) LDTP07813 13.74  LDD1919 
Thiol S-methyltransferase TMT1A (TMT1A) LDTP12056 14.32  LDD1919 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 13.83  LDD1919 
Threonine--tRNA ligase, mitochondrial (TARS2) LDTP11319 12.47  LDD1919 
TLC domain-containing protein 1 (TLCD1) LDTP10182 15.78  LDD1919 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 36.50  LDD1919 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 29.04  LDD1919 
UbiA prenyltransferase domain-containing protein 1 (UBIAD1) LDTP14189 15.89  LDD1919 
Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 13.64  LDD1919 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 13.55  LDD1919 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 20.82  LDD1919 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 13.18  LDD1919 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 79.34  LDD1919 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 14.42  LDD1919 
------------------------------------------------------------------------------------
⏷ Show the Full List of 142 Enzyme
117 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 14.83  LDD1919 
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 12.47  LDD1919 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 12.21  LDD1919 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 12.64  LDD1919 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 13.93  LDD1919 
ATP synthase subunit a (MT-ATP6) LDTP01804 55.72  LDD1919 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 41.93  LDD1919 
Autophagy-related protein 9A (ATG9A) LDTP08030 14.62  LDD1919 
BOS complex subunit NCLN (NCLN) LDTP10036 48.17  LDD1919 
BRI3-binding protein (BRI3BP) LDTP15648 22.63  LDD1919 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 24.59  LDD1919 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 64.45  LDD1919 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 19.43  LDD1919 
Derlin-1 (DERL1) LDTP11245 27.28  LDD1919 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 13.09  LDD1919 
Endophilin-B1 (SH3GLB1) LDTP13953 12.38  LDD1919 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 52.35  LDD1919 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 24.76  LDD1919 
Erlin-1 (ERLIN1) LDTP01234 20.97  LDD1919 
Erlin-2 (ERLIN2) LDTP01455 24.93  LDD1919 
Glucose-6-phosphate exchanger SLC37A4 (SLC37A4) LDTP00882 17.39  LDD1919 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 32.67  LDD1919 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 18.64  LDD1919 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 20.68  LDD1919 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 17.75  LDD1919 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 21.56  LDD1919 
Importin subunit alpha-1 (KPNA2) LDTP04501 20.39  LDD1919 
Integral membrane protein 2B (ITM2B) LDTP13833 16.34  LDD1919 
Intraflagellar transport protein 56 (IFT56) LDTP00010 13.93  LDD1919 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 13.27  LDD1919 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 18.25  LDD1919 
Lysosome membrane protein 2 (SCARB2) LDTP06034 14.52  LDD1919 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 23.59  LDD1919 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 13.18  LDD1919 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 29.45  LDD1919 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 18.00  LDD1919 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 14.72  LDD1919 
Metaxin-1 (MTX1) LDTP05900 39.40  LDD1919 
MICOS complex subunit MIC26 (APOO) LDTP11250 24.25  LDD1919 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 14.62  LDD1919 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 17.51  LDD1919 
Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) LDTP08279 14.52  LDD1919 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 48.17  LDD1919 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 40.79  LDD1919 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 42.81  LDD1919 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 66.26  LDD1919 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 38.85  LDD1919 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 19.29  LDD1919 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 31.78  LDD1919 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 15.78  LDD1919 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 19.84  LDD1919 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 26.35  LDD1919 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 13.00  LDD1919 
Mpv17-like protein 2 (MPV17L2) LDTP14952 22.32  LDD1919 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 16.68  LDD1919 
Nucleoporin NDC1 (NDC1) LDTP11213 16.80  LDD1919 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 22.01  LDD1919 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 14.42  LDD1919 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 17.51  LDD1919 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 18.13  LDD1919 
Peroxisomal membrane protein PMP34 (SLC25A17) LDTP00872 12.64  LDD1919 
PRA1 family protein 2 (PRAF2) LDTP01060 16.56  LDD1919 
Prenylated Rab acceptor protein 1 (RABAC1) LDTP13320 12.91  LDD1919 
Programmed cell death protein 6 (PDCD6) LDTP01180 17.39  LDD1919 
Prosaposin (PSAP) LDTP02215 22.32  LDD1919 
Protein ERGIC-53 (LMAN1) LDTP04237 17.15  LDD1919 
Protein FAM8A1 (FAM8A1) LDTP16190 20.68  LDD1919 
Protein GPR107 (GPR107) LDTP07236 44.32  LDD1919 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 16.68  LDD1919 
Protein tweety homolog 3 (TTYH3) LDTP11615 31.12  LDD1919 
Protein wntless homolog (WLS) LDTP07156 38.05  LDD1919 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 24.42  LDD1919 
Proton-coupled zinc antiporter SLC30A9, mitochondrial (SLC30A9) LDTP07610 14.22  LDD1919 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 14.12  LDD1919 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 24.93  LDD1919 
Rhomboid domain-containing protein 2 (RHBDD2) LDTP07467 19.70  LDD1919 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 18.38  LDD1919 
Sideroflexin-4 (SFXN4) LDTP07531 13.55  LDD1919 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 14.12  LDD1919 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 13.74  LDD1919 
Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) LDTP02544 13.93  LDD1919 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 53.45  LDD1919 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 23.43  LDD1919 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 14.42  LDD1919 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 15.03  LDD1919 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 22.16  LDD1919 
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (SDHC) LDTP10931 14.52  LDD1919 
SUN domain-containing protein 2 (SUN2) LDTP13256 12.82  LDD1919 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 15.03  LDD1919 
Syntaxin-4 (STX4) LDTP05667 15.03  LDD1919 
Tetraspanin-3 (TSPAN3) LDTP16813 57.68  LDD1919 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 14.12  LDD1919 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 43.11  LDD1919 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 88.65  LDD1919 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 13.09  LDD1919 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 18.13  LDD1919 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 12.47  LDD1919 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 30.06  LDD1919 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 14.83  LDD1919 
Transmembrane protein 126A (TMEM126A) LDTP15948 57.28  LDD1919 
Transmembrane protein 160 (TMEM160) LDTP20002 51.98  LDD1919 
Transmembrane protein 199 (TMEM199) LDTP08881 36.00  LDD1919 
Transmembrane protein 201 (TMEM201) LDTP07058 15.14  LDD1919 
Transmembrane protein 205 (TMEM205) LDTP07667 14.52  LDD1919 
Transmembrane protein 214 (TMEM214) LDTP07477 12.38  LDD1919 
Transmembrane protein 230 (TMEM230) LDTP10065 24.76  LDD1919 
Transmembrane protein 245 (TMEM245) LDTP15979 18.38  LDD1919 
Transmembrane protein 33 (TMEM33) LDTP04787 17.51  LDD1919 
Transmembrane protein 65 (TMEM65) LDTP07583 13.09  LDD1919 
Transmembrane protein 87A (TMEM87A) LDTP15481 55.72  LDD1919 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 22.63  LDD1919 
Vang-like protein 1 (VANGL1) LDTP09288 13.18  LDD1919 
Vezatin (VEZT) LDTP12191 16.34  LDD1919 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 38.59  LDD1919 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 47.18  LDD1919 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 24.42  LDD1919 
Wolframin (WFS1) LDTP01380 19.84  LDD1919 
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⏷ Show the Full List of 117 Transporter and channel
3 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 16.00  LDD1919 
Paraspeckle component 1 (PSPC1) LDTP09694 18.13  LDD1919 
Transcriptional enhancer factor TEF-3 (TEAD4) LDTP06415 44.63  LDD1919 
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3 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 18.13  LDD1919 
Cell adhesion molecule 1 (CADM1) LDTP11441 12.64  LDD1919 
Leukocyte surface antigen CD47 (CD47) LDTP05572 16.34  LDD1919 
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101 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 12.21  LDD1919 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 18.25  LDD1919 
Angiomotin (AMOT) LDTP06868 13.45  LDD1919 
Ankyrin repeat domain-containing protein 46 (ANKRD46) LDTP08320 12.21  LDD1919 
Apolipoprotein L2 (APOL2) LDTP11076 99.73  LDD1919 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 12.38  LDD1919 
BSD domain-containing protein 1 (BSDC1) LDTP16116 16.34  LDD1919 
Centrin-2 (CETN2) LDTP03926 13.18  LDD1919 
Clustered mitochondria protein homolog (CLUH) LDTP14486 19.03  LDD1919 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 12.38  LDD1919 
Complex I intermediate-associated protein 30, mitochondrial (NDUFAF1) LDTP13954 17.51  LDD1919 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 22.16  LDD1919 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 76.64  LDD1919 
DnaJ homolog subfamily C member 11 (DNAJC11) LDTP12677 13.36  LDD1919 
Dynactin subunit 3 (DCTN3) LDTP01359 12.30  LDD1919 
Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) LDTP10046 12.30  LDD1919 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 19.70  LDD1919 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 52.71  LDD1919 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 39.67  LDD1919 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 39.95  LDD1919 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 12.38  LDD1919 
Ganglioside GM2 activator (GM2A) LDTP02927 26.54  LDD1919 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 15.78  LDD1919 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 41.36  LDD1919 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 16.22  LDD1919 
HAUS augmin-like complex subunit 3 (HAUS3) LDTP07318 13.18  LDD1919 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 13.64  LDD1919 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 22.16  LDD1919 
HCLS1-associated protein X-1 (HAX1) LDTP00199 16.45  LDD1919 
HIG1 domain family member 1A, mitochondrial (HIGD1A) LDTP13797 18.51  LDD1919 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 14.93  LDD1919 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 14.72  LDD1919 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 37.53  LDD1919 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 15.67  LDD1919 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 12.21  LDD1919 
Lipase maturation factor 2 (LMF2) LDTP15887 20.11  LDD1919 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 32.67  LDD1919 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 23.59  LDD1919 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 18.90  LDD1919 
Membralin (TMEM259) LDTP14939 78.25  LDD1919 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 23.10  LDD1919 
MICOS complex subunit MIC27 (APOOL) LDTP07718 13.93  LDD1919 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 12.73  LDD1919 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 34.06  LDD1919 
Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) LDTP14126 15.03  LDD1919 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 41.07  LDD1919 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 36.50  LDD1919 
Mitochondrial import receptor subunit TOM7 homolog (TOMM7) LDTP12982 27.67  LDD1919 
Mitochondrial potassium channel (CCDC51) LDTP10275 13.45  LDD1919 
Neurofilament light polypeptide (NEFL) LDTP02180 14.22  LDD1919 
Nicastrin (NCSTN) LDTP09787 12.21  LDD1919 
NLR family member X1 (NLRX1) LDTP08248 12.91  LDD1919 
Nucleobindin-1 (NUCB1) LDTP05375 17.27  LDD1919 
Nucleobindin-2 (NUCB2) LDTP05160 55.33  LDD1919 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 16.68  LDD1919 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 13.27  LDD1919 
Nurim (NRM) LDTP08606 15.45  LDD1919 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 19.43  LDD1919 
Optic atrophy 3 protein (OPA3) LDTP16006 53.08  LDD1919 
p53 and DNA damage-regulated protein 1 (PDRG1) LDTP16099 61.39  LDD1919 
Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) LDTP11906 16.22  LDD1919 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 41.36  LDD1919 
PRELI domain containing protein 3B (PRELID3B) LDTP18569 13.74  LDD1919 
Prohibitin-2 (PHB2) LDTP10924 13.00  LDD1919 
Protein CEBPZOS (CEBPZOS) LDTP18883 28.44  LDD1919 
Protein FAM114A2 (FAM114A2) LDTP16080 19.84  LDD1919 
Protein FAM162A (FAM162A) LDTP10056 45.25  LDD1919 
Protein FAM177A1 (FAM177A1) LDTP15398 16.68  LDD1919 
Protein FAM210A (FAM210A) LDTP15793 13.18  LDD1919 
Protein jagunal homolog 1 (JAGN1) LDTP08904 25.63  LDD1919 
Protein LYRIC (MTDH) LDTP08224 31.34  LDD1919 
Protein SET (SET) LDTP05277 19.70  LDD1919 
Protein SYS1 homolog (SYS1) LDTP08796 44.63  LDD1919 
Protein YIF1A (YIF1A) LDTP01494 18.51  LDD1919 
Protein YIF1B (YIF1B) LDTP06948 15.56  LDD1919 
Receptor expression-enhancing protein 2 (REEP2) LDTP11113 12.73  LDD1919 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 23.10  LDD1919 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 15.35  LDD1919 
Reticulocalbin-2 (RCN2) LDTP06097 18.90  LDD1919 
Reticulon-3 (RTN3) LDTP01522 83.87  LDD1919 
Reticulon-4 (RTN4) LDTP12412 35.51  LDD1919 
Reticulophagy regulator 3 (RETREG3) LDTP08300 14.83  LDD1919 
RNA-binding protein FUS (FUS) LDTP03775 12.21  LDD1919 
RUS family member 1 (RUSF1) LDTP10357 13.18  LDD1919 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 13.45  LDD1919 
Signal transducing adapter molecule 1 (STAM) LDTP09870 19.03  LDD1919 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 13.36  LDD1919 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 16.11  LDD1919 
Survival motor neuron protein (SMN1; SMN2) LDTP06587 13.36  LDD1919 
Synaptogyrin-2 (SYNGR2) LDTP00859 45.25  LDD1919 
Syntaxin-10 (STX10) LDTP00986 49.18  LDD1919 
Syntaxin-18 (STX18) LDTP13086 34.30  LDD1919 
Syntaxin-7 (STX7) LDTP00632 12.38  LDD1919 
TBC1 domain family member 13 (TBC1D13) LDTP16107 13.45  LDD1919 
Testis-expressed protein 264 (TEX264) LDTP14259 14.72  LDD1919 
Tetraspanin-6 (TSPAN6) LDTP14458 21.56  LDD1919 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 52.71  LDD1919 
TraB domain-containing protein (TRABD) LDTP19963 22.32  LDD1919 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 13.64  LDD1919 
Transmembrane protein 35B (TMEM35B) LDTP19785 26.91  LDD1919 
Vimentin (VIM) LDTP02297 12.64  LDD1919 
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⏷ Show the Full List of 101 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1919 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587