Details of the Target

General Information of Target

Target ID LDTP19785
Target Name Transmembrane protein 35B (TMEM35B)
Gene Name TMEM35B
Gene ID 100506144
Synonyms
ZMYM6NB; Transmembrane protein 35B; ZMYM6 neighbor protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPSSHIVLKEETRMLGLMYAIWMNLNSFGLAIIGILLIACEIILFLTKDETIQWPHVPSN
RGSKANLILKELQLLVRSTWWFHRETAQRTCLYLA
Target Bioclass
Other
Family
DoxX family
Subcellular location
Membrane
Uniprot ID
Q8NCS4
Ensemble ID
ENST00000373337.4
HGNC ID
HGNC:40021

Probe(s) Labeling This Target

PAL-AfBPP Probe
Click To Hide/Show 9 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C055
 Probe Info  		18.38  LDD1752  [1]
C056
 Probe Info  		42.81  LDD1753  [1]
C141
 Probe Info  		13.00  LDD1823  [1]
C143
 Probe Info  		22.01  LDD1825  [1]
C243
 Probe Info  		15.78  LDD1916  [1]
C244
 Probe Info  		23.92  LDD1917  [1]
C246
 Probe Info  		26.91  LDD1919  [1]
C249
 Probe Info  		13.36  LDD1922  [1]
OEA-DA
 Probe Info  		15.89  LDD0046  [2]

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
2 Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20.
Mass spectrometry data entry: PXD007570