Details of the Probe

General Information of Probe

Probe ID
LDPC0313
Probe Name
C056
Synonyms
Z3433407586
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 347.4
Lipid-water partition coefficient (xlogp) 2.8
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C19H17N5O2
IUPAC Name
5-(1-benzofuran-2-yl)-N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-1H-pyrazole-4-carboxamide
Canonical SMILES
C#CCCC1(N=N1)CCNC(=O)C2=C(NN=C2)C3=CC4=CC=CC=C4O3
InChI
InChI=1S/C19H17N5O2/c1-2-3-8-19(23-24-19)9-10-20-18(25)14-12-21-22-17(14)16-11-13-6-4-5-7-15(13)26-16/h1,4-7,11-12H,3,8-10H2,(H,20,25)(H,21,22)
InChIKey
FOWQQPALPXONHH-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

164 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 37.79  LDD1753 
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 (OGFOD3) LDTP15132 19.03  LDD1753 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 24.25  LDD1753 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 21.26  LDD1753 
Abasic site processing protein HMCES (HMCES) LDTP10322 42.81  LDD1753 
Acid ceramidase (ASAH1) LDTP05905 16.91  LDD1753 
Acyl-CoA dehydrogenase family member 10 (ACAD10) LDTP07435 16.11  LDD1753 
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) LDTP09814 18.13  LDD1753 
Adenosine 5'-monophosphoramidase HINT3 (HINT3) LDTP12415 16.34  LDD1753 
Adenosine deaminase (ADA) LDTP01803 99.73  LDD1753 
Adenosine kinase (ADK) LDTP04689 21.56  LDD1753 
ADP-dependent glucokinase (ADPGK) LDTP11127 67.65  LDD1753 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 60.97  LDD1753 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 59.30  LDD1753 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 19.29  LDD1753 
Atlastin-2 (ATL2) LDTP09251 23.59  LDD1753 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 18.64  LDD1753 
ATP-dependent RNA helicase DHX8 (DHX8) LDTP06147 16.34  LDD1753 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 16.22  LDD1753 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 26.72  LDD1753 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 18.51  LDD1753 
Atypical kinase COQ8A, mitochondrial (COQ8A) LDTP09285 19.29  LDD1753 
Beta-1,3-galactosyltransferase 6 (B3GALT6) LDTP10530 17.75  LDD1753 
Beta-1,4-galactosyltransferase 1 (B4GALT1) LDTP02777 16.91  LDD1753 
Beta-1,4-galactosyltransferase 3 (B4GALT3) LDTP00994 18.38  LDD1753 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 29.24  LDD1753 
Calcium-transporting ATPase type 2C member 1 (ATP2C1) LDTP05228 17.27  LDD1753 
Calcium/calmodulin-dependent protein kinase type 1 (CAMK1) LDTP06023 17.39  LDD1753 
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G) LDTP05920 16.11  LDD1753 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 46.85  LDD1753 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 22.47  LDD1753 
Catechol O-methyltransferase (COMT) LDTP03145 26.54  LDD1753 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 51.98  LDD1753 
Ceramide glucosyltransferase (UGCG) LDTP06617 31.12  LDD1753 
Ceramide synthase 1 (CERS1) LDTP03394 37.79  LDD1753 
Ceramide synthase 2 (CERS2) LDTP10329 51.27  LDD1753 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 32.90  LDD1753 
Choline/ethanolaminephosphotransferase 1 (CEPT1) LDTP14264 31.12  LDD1753 
Cyclin-dependent kinase 16 (CDK16) LDTP05246 26.35  LDD1753 
Cyclin-G-associated kinase (GAK) LDTP00497 19.43  LDD1753 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 16.11  LDD1753 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 28.64  LDD1753 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 96.34  LDD1753 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 86.82  LDD1753 
Cytochrome b5 type B (CYB5B) LDTP00697 71.51  LDD1753 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 41.36  LDD1753 
Cytochrome c oxidase subunit 6C (COX6C) LDTP02367 16.91  LDD1753 
Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L) LDTP14427 21.71  LDD1753 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 60.13  LDD1753 
DCN1-like protein 4 (DCUN1D4) LDTP09799 17.51  LDD1753 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 36.50  LDD1753 
Dehydrogenase/reductase SDR family member 7 (DHRS7) LDTP13959 17.39  LDD1753 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 18.25  LDD1753 
Delta(24)-sterol reductase (DHCR24) LDTP06375 30.70  LDD1753 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 25.11  LDD1753 
Dihydrofolate reductase (DHFR) LDTP01769 16.56  LDD1753 
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM17) LDTP05137 16.68  LDD1753 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 27.86  LDD1753 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 21.41  LDD1753 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 98.36  LDD1753 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 20.39  LDD1753 
E3 ubiquitin-protein ligase AMFR (AMFR) LDTP13491 27.67  LDD1753 
E3 ubiquitin-protein ligase MARCHF5 (MARCHF5) LDTP12757 18.90  LDD1753 
E3 ubiquitin-protein ligase TRIM13 (TRIM13) LDTP01065 49.52  LDD1753 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 33.36  LDD1753 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 28.64  LDD1753 
Epimerase family protein SDR39U1 (SDR39U1) LDTP16070 17.75  LDD1753 
Epoxide hydrolase 1 (EPHX1) LDTP02175 24.59  LDD1753 
Ferrochelatase, mitochondrial (FECH) LDTP03198 72.00  LDD1753 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 30.06  LDD1753 
Glycerophosphodiester phosphodiesterase 1 (GDE1) LDTP12886 19.43  LDD1753 
Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) LDTP17305 25.81  LDD1753 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 21.11  LDD1753 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 20.25  LDD1753 
GTP-binding protein SAR1a (SAR1A) LDTP12470 22.01  LDD1753 
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) LDTP13352 23.59  LDD1753 
Heme A synthase COX15 (COX15) LDTP07931 28.25  LDD1753 
Heme oxygenase 1 (HMOX1) LDTP02359 41.64  LDD1753 
Heme oxygenase 2 (HMOX2) LDTP03540 53.82  LDD1753 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 45.89  LDD1753 
Hexokinase-2 (HK2) LDTP04531 17.39  LDD1753 
Holocytochrome c-type synthase (HCCS) LDTP04581 17.27  LDD1753 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 69.55  LDD1753 
Inositol 1,4,5-trisphosphate receptor-interacting protein (ITPRIP) LDTP08532 54.19  LDD1753 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 27.28  LDD1753 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 36.25  LDD1753 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 19.56  LDD1753 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 21.56  LDD1753 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 17.63  LDD1753 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 30.70  LDD1753 
Macrophage migration inhibitory factor (MIF) LDTP02713 23.92  LDD1753 
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) LDTP10930 27.10  LDD1753 
Methionine aminopeptidase 1 (METAP1) LDTP04565 17.63  LDD1753 
Methionine synthase (MTR) LDTP10951 16.11  LDD1753 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 18.13  LDD1753 
Microsomal glutathione S-transferase 2 (MGST2) LDTP10966 17.75  LDD1753 
Minor histocompatibility antigen H13 (HM13) LDTP09396 18.25  LDD1753 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 29.65  LDD1753 
Mitochondrial import inner membrane translocase subunit TIM50 (TIMM50) LDTP06810 17.15  LDD1753 
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (PIGL) LDTP16258 21.71  LDD1753 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 22.16  LDD1753 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 54.19  LDD1753 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 16.91  LDD1753 
NADH dehydrogenase 1 alpha subcomplex subunit 3 (NDUFA3) LDTP01513 38.05  LDD1753 
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) LDTP01219 32.90  LDD1753 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 27.28  LDD1753 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 99.73  LDD1753 
NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) LDTP01502 47.18  LDD1753 
NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial (NDUFB8) LDTP01515 16.91  LDD1753 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 24.76  LDD1753 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 29.45  LDD1753 
NADPH--cytochrome P450 reductase (POR) LDTP02848 24.08  LDD1753 
Neutral cholesterol ester hydrolase 1 (NCEH1) LDTP07591 17.39  LDD1753 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 17.39  LDD1753 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 36.76  LDD1753 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 74.54  LDD1753 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 23.92  LDD1753 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 35.51  LDD1753 
Phenylalanine--tRNA ligase beta subunit (FARSB) LDTP12586 22.16  LDD1753 
Phosphatidate cytidylyltransferase, mitochondrial (TAMM41) LDTP10144 19.03  LDD1753 
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (PTPMT1) LDTP09578 16.68  LDD1753 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 19.43  LDD1753 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 21.41  LDD1753 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 19.56  LDD1753 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 45.25  LDD1753 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 18.13  LDD1753 
Presenilin-associated rhomboid-like protein, mitochondrial (PARL) LDTP11852 32.22  LDD1753 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 19.43  LDD1753 
Prostaglandin reductase 3 (PTGR3) LDTP15422 18.25  LDD1753 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 16.68  LDD1753 
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGNT2) LDTP09031 23.43  LDD1753 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 21.26  LDD1753 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 20.53  LDD1753 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 35.02  LDD1753 
Rab-like protein 3 (RABL3) LDTP06986 17.15  LDD1753 
Ras-related protein Rab-10 (RAB10) LDTP04895 17.15  LDD1753 
Ras-related protein Rab-11B (RAB11B) LDTP06501 25.63  LDD1753 
Ras-related protein Rab-24 (RAB24) LDTP10020 42.52  LDD1753 
Ras-related protein Rab-34 (RAB34) LDTP11535 20.11  LDD1753 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 22.01  LDD1753 
Retinol dehydrogenase 13 (RDH13) LDTP09061 16.91  LDD1753 
Ribitol 5-phosphate transferase FKRP (FKRP) LDTP12109 17.51  LDD1753 
RNA cytidine acetyltransferase (NAT10) LDTP11690 17.63  LDD1753 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 23.43  LDD1753 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 26.54  LDD1753 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 50.56  LDD1753 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 99.73  LDD1753 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 24.93  LDD1753 
Sphingosine kinase 2 (SPHK2) LDTP12490 26.35  LDD1753 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 39.95  LDD1753 
Squalene monooxygenase (SQLE) LDTP06142 23.75  LDD1753 
Squalene synthase (FDFT1) LDTP03842 21.11  LDD1753 
SRSF protein kinase 1 (SRPK1) LDTP10809 16.56  LDD1753 
Sulfide:quinone oxidoreductase, mitochondrial (SQOR) LDTP14278 23.43  LDD1753 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 21.86  LDD1753 
TLC domain-containing protein 1 (TLCD1) LDTP10182 18.64  LDD1753 
Torsin-1B (TOR1B) LDTP00400 18.00  LDD1753 
UbiA prenyltransferase domain-containing protein 1 (UBIAD1) LDTP14189 25.99  LDD1753 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) LDTP07756 22.16  LDD1753 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 18.25  LDD1753 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 21.56  LDD1753 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 16.22  LDD1753 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 28.05  LDD1753 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 26.17  LDD1753 
------------------------------------------------------------------------------------
⏷ Show the Full List of 164 Enzyme
129 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 17.63  LDD1753 
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 17.03  LDD1753 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 41.07  LDD1753 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 34.78  LDD1753 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 19.56  LDD1753 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 18.00  LDD1753 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 66.26  LDD1753 
ATP synthase subunit a (MT-ATP6) LDTP01804 64.89  LDD1753 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 17.39  LDD1753 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 74.03  LDD1753 
B-cell receptor-associated protein 31 (BCAP31) LDTP04426 18.25  LDD1753 
Bardet-Biedl syndrome 4 protein (BBS4) LDTP10766 16.68  LDD1753 
BRI3-binding protein (BRI3BP) LDTP15648 88.65  LDD1753 
Calcium load-activated calcium channel (TMCO1) LDTP13599 17.27  LDD1753 
Calnexin (CANX) LDTP03405 24.42  LDD1753 
Ceroid-lipofuscinosis neuronal protein 6 (CLN6) LDTP12738 23.75  LDD1753 
Chloride channel CLIC-like protein 1 (CLCC1) LDTP10804 17.75  LDD1753 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 29.45  LDD1753 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 27.86  LDD1753 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 45.57  LDD1753 
Cytochrome c oxidase subunit 5A, mitochondrial (COX5A) LDTP03064 17.51  LDD1753 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 72.00  LDD1753 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 26.72  LDD1753 
Derlin-1 (DERL1) LDTP11245 49.52  LDD1753 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 22.32  LDD1753 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 28.64  LDD1753 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 79.89  LDD1753 
Essential MCU regulator, mitochondrial (SMDT1) LDTP11927 99.73  LDD1753 
Etoposide-induced protein 2.4 homolog (EI24) LDTP00405 21.26  LDD1753 
Exocyst complex component 3 (EXOC3) LDTP01016 32.67  LDD1753 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 32.67  LDD1753 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 16.68  LDD1753 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 32.22  LDD1753 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 32.90  LDD1753 
Integral membrane protein 2C (ITM2C) LDTP12451 16.11  LDD1753 
Intermembrane lipid transfer protein VPS13A (VPS13A) LDTP10769 33.13  LDD1753 
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) LDTP01100 26.35  LDD1753 
Large neutral amino acids transporter small subunit 1 (SLC7A5) LDTP05305 19.16  LDD1753 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 22.94  LDD1753 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 27.86  LDD1753 
Lysosomal cobalamin transport escort protein LMBD1 (LMBRD1) LDTP12636 30.27  LDD1753 
Lysosomal-associated transmembrane protein 4A (LAPTM4A) LDTP06275 25.28  LDD1753 
Lysosome membrane protein 2 (SCARB2) LDTP06034 22.01  LDD1753 
Major facilitator superfamily domain-containing protein 10 (MFSD10) LDTP06198 19.56  LDD1753 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 39.40  LDD1753 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 31.56  LDD1753 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 64.89  LDD1753 
Metaxin-1 (MTX1) LDTP05900 71.01  LDD1753 
Metaxin-2 (MTX2) LDTP01217 29.24  LDD1753 
MICOS complex subunit MIC26 (APOO) LDTP11250 25.63  LDD1753 
MICOS complex subunit MIC60 (IMMT) LDTP06660 17.63  LDD1753 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 36.50  LDD1753 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 19.16  LDD1753 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 30.27  LDD1753 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 29.24  LDD1753 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 38.85  LDD1753 
Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) LDTP08279 64.00  LDD1753 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 43.71  LDD1753 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 73.52  LDD1753 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD1753 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD1753 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 48.17  LDD1753 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 27.86  LDD1753 
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 19.84  LDD1753 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 44.94  LDD1753 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 21.71  LDD1753 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 43.41  LDD1753 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 20.25  LDD1753 
Mpv17-like protein 2 (MPV17L2) LDTP14952 22.32  LDD1753 
Multiple coagulation factor deficiency protein 2 (MCFD2) LDTP09278 33.59  LDD1753 
Nucleoporin NDC1 (NDC1) LDTP11213 19.43  LDD1753 
Pannexin-1 (PANX1) LDTP10754 16.11  LDD1753 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 26.54  LDD1753 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 20.11  LDD1753 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 35.02  LDD1753 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 18.77  LDD1753 
Peroxisomal membrane protein PMP34 (SLC25A17) LDTP00872 28.84  LDD1753 
PRA1 family protein 2 (PRAF2) LDTP01060 33.36  LDD1753 
Prosaposin (PSAP) LDTP02215 25.81  LDD1753 
Protein ARV1 (ARV1) LDTP11812 17.51  LDD1753 
Protein FAM8A1 (FAM8A1) LDTP16190 26.17  LDD1753 
Protein GPR107 (GPR107) LDTP07236 33.59  LDD1753 
Protein GPR108 (GPR108) LDTP12383 32.45  LDD1753 
Protein Mpv17 (MPV17) LDTP03869 17.03  LDD1753 
Protein RFT1 homolog (RFT1) LDTP10073 20.82  LDD1753 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 18.77  LDD1753 
Protein spinster homolog 1 (SPNS1) LDTP11844 27.28  LDD1753 
Protein wntless homolog (WLS) LDTP07156 20.97  LDD1753 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 24.93  LDD1753 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 43.71  LDD1753 
Ran-binding protein 6 (RANBP6) LDTP16811 20.68  LDD1753 
Renin receptor (ATP6AP2) LDTP01309 18.00  LDD1753 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 19.97  LDD1753 
Sideroflexin-4 (SFXN4) LDTP07531 21.41  LDD1753 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 32.00  LDD1753 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 41.93  LDD1753 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 56.49  LDD1753 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 22.78  LDD1753 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 29.86  LDD1753 
Surfeit locus protein 4 (SURF4) LDTP00592 22.94  LDD1753 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 49.87  LDD1753 
Tetraspanin-3 (TSPAN3) LDTP16813 41.36  LDD1753 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 25.28  LDD1753 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 32.67  LDD1753 
Translocation protein SEC62 (SEC62) LDTP15838 17.03  LDD1753 
Translocator protein (TSPO) LDTP03546 99.73  LDD1753 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD1753 
Translocon-associated protein subunit beta (SSR2) LDTP14682 22.94  LDD1753 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 25.46  LDD1753 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 22.01  LDD1753 
Transmembrane protein 126A (TMEM126A) LDTP15948 43.11  LDD1753 
Transmembrane protein 14C (TMEM14C) LDTP12979 20.82  LDD1753 
Transmembrane protein 160 (TMEM160) LDTP20002 84.45  LDD1753 
Transmembrane protein 199 (TMEM199) LDTP08881 44.94  LDD1753 
Transmembrane protein 205 (TMEM205) LDTP07667 17.51  LDD1753 
Transmembrane protein 230 (TMEM230) LDTP10065 55.72  LDD1753 
Transmembrane protein 245 (TMEM245) LDTP15979 22.94  LDD1753 
Transmembrane protein 33 (TMEM33) LDTP04787 20.97  LDD1753 
Transmembrane protein 59 (TMEM59) LDTP11406 28.84  LDD1753 
Transmembrane protein 87A (TMEM87A) LDTP15481 32.45  LDD1753 
Vacuole membrane protein 1 (VMP1) LDTP10343 30.91  LDD1753 
Vang-like protein 1 (VANGL1) LDTP09288 33.82  LDD1753 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 63.56  LDD1753 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 48.84  LDD1753 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 31.78  LDD1753 
Voltage-gated monoatomic cation channel TMEM109 (TMEM109) LDTP11281 16.22  LDD1753 
Wolframin (WFS1) LDTP01380 17.75  LDD1753 
Zinc transporter 7 (SLC30A7) LDTP09180 36.25  LDD1753 
Zinc transporter ZIP11 (SLC39A11) LDTP17682 22.94  LDD1753 
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⏷ Show the Full List of 129 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 41.07  LDD1753 
Zinc finger MYM-type protein 1 (ZMYM1) LDTP19380 16.80  LDD1753 
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2 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Golgi pH regulator B (GPR89B) LDTP14610 16.11  LDD1753 
Membrane progestin receptor alpha (PAQR7) LDTP15303 31.12  LDD1753 
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4 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 25.99  LDD1753 
HLA class I histocompatibility antigen, alpha chain F (HLA-F) LDTP03538 36.00  LDD1753 
Leukocyte surface antigen CD47 (CD47) LDTP05572 29.04  LDD1753 
Neuroplastin (NPTN) LDTP14205 31.34  LDD1753 
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139 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 30.91  LDD1753 
ADP-ribosylation factor-like protein 6-interacting protein 6 (ARL6IP6) LDTP15434 24.76  LDD1753 
Alpha-internexin (INA) LDTP06527 20.11  LDD1753 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 21.56  LDD1753 
Apolipoprotein C-I (APOC1) LDTP01938 34.06  LDD1753 
Apolipoprotein L2 (APOL2) LDTP11076 70.52  LDD1753 
ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) LDTP14716 33.59  LDD1753 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 25.46  LDD1753 
BSD domain-containing protein 1 (BSDC1) LDTP16116 17.75  LDD1753 
Calmodulin-3 (CALM3) LDTP02443 23.26  LDD1753 
Centrin-2 (CETN2) LDTP03926 86.22  LDD1753 
Charged multivesicular body protein 5 (CHMP5) LDTP12948 18.64  LDD1753 
Clustered mitochondria protein homolog (CLUH) LDTP14486 23.75  LDD1753 
Coiled-coil domain-containing protein 127 (CCDC127) LDTP20361 30.06  LDD1753 
Coiled-coil domain-containing protein 97 (CCDC97) LDTP19860 17.27  LDD1753 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 17.15  LDD1753 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 99.73  LDD1753 
Cytochrome c oxidase assembly protein COX14 (COX14) LDTP15741 25.11  LDD1753 
Dedicator of cytokinesis protein 1 (DOCK1) LDTP06072 25.81  LDD1753 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 17.27  LDD1753 
Divergent protein kinase domain 2A (DIPK2A) LDTP09143 28.84  LDD1753 
DNA replication complex GINS protein PSF2 (GINS2) LDTP13802 18.77  LDD1753 
Dymeclin (DYM) LDTP08000 17.39  LDD1753 
Dynactin subunit 3 (DCTN3) LDTP01359 27.28  LDD1753 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 30.70  LDD1753 
Emerin (EMD) LDTP04356 16.80  LDD1753 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 28.64  LDD1753 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 42.52  LDD1753 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 45.25  LDD1753 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 26.35  LDD1753 
FUN14 domain-containing protein 1 (FUNDC1) LDTP08509 20.53  LDD1753 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 25.63  LDD1753 
Galanin peptides (GAL) LDTP03175 56.49  LDD1753 
Glycolipid transfer protein (GLTP) LDTP12891 73.01  LDD1753 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 57.28  LDD1753 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 19.16  LDD1753 
Golgi SNAP receptor complex member 2 (GOSR2) LDTP00397 18.90  LDD1753 
HAUS augmin-like complex subunit 1 (HAUS1) LDTP10184 19.70  LDD1753 
HCLS1-associated protein X-1 (HAX1) LDTP00199 17.15  LDD1753 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 20.39  LDD1753 
Heme-binding protein 1 (HEBP1) LDTP16078 18.38  LDD1753 
HIG1 domain family member 1A, mitochondrial (HIGD1A) LDTP13797 41.07  LDD1753 
Histone H3.3 (H3-3A; H3-3B) LDTP05198 16.22  LDD1753 
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) LDTP05530 26.35  LDD1753 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 21.71  LDD1753 
Intermembrane lipid transfer protein VPS13D (VPS13D) LDTP07192 26.72  LDD1753 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 27.67  LDD1753 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 25.81  LDD1753 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 48.17  LDD1753 
Lipid droplet assembly factor 1 (LDAF1) LDTP10116 20.53  LDD1753 
LYR motif-containing protein 2 (LYRM2) LDTP18467 54.19  LDD1753 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 33.13  LDD1753 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 25.11  LDD1753 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 44.02  LDD1753 
Membralin (TMEM259) LDTP14939 56.10  LDD1753 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 44.63  LDD1753 
MICOS complex subunit MIC27 (APOOL) LDTP07718 19.97  LDD1753 
Mitochondrial fission 1 protein (FIS1) LDTP13982 17.39  LDD1753 
Mitochondrial fission factor (MFF) LDTP11670 42.81  LDD1753 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 22.32  LDD1753 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 24.59  LDD1753 
Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) LDTP14126 37.79  LDD1753 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 96.34  LDD1753 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 99.73  LDD1753 
Mitochondrial import receptor subunit TOM7 homolog (TOMM7) LDTP12982 29.04  LDD1753 
Negative elongation factor C/D (NELFCD) LDTP08594 30.48  LDD1753 
Neuferricin (CYB5D2) LDTP15623 16.45  LDD1753 
Neurofilament light polypeptide (NEFL) LDTP02180 20.82  LDD1753 
Neurofilament medium polypeptide (NEFM) LDTP02181 16.45  LDD1753 
Nucleobindin-1 (NUCB1) LDTP05375 50.91  LDD1753 
Nucleobindin-2 (NUCB2) LDTP05160 39.67  LDD1753 
Nurim (NRM) LDTP08606 30.48  LDD1753 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 27.86  LDD1753 
Optic atrophy 3 protein (OPA3) LDTP16006 41.64  LDD1753 
Phosducin-like protein 3 (PDCL3) LDTP11825 24.25  LDD1753 
Polyadenylate-binding protein-interacting protein 2 (PAIP2) LDTP11044 18.00  LDD1753 
Prefoldin subunit 6 (PFDN6) LDTP00573 18.64  LDD1753 
PRELI domain containing protein 3B (PRELID3B) LDTP18569 26.17  LDD1753 
Prohibitin-2 (PHB2) LDTP10924 19.70  LDD1753 
Protein C3orf33 (C3orf33) LDTP15110 60.55  LDD1753 
Protein CEBPZOS (CEBPZOS) LDTP18883 63.12  LDD1753 
Protein CutA (CUTA) LDTP01075 16.22  LDD1753 
Protein FAM114A2 (FAM114A2) LDTP16080 66.26  LDD1753 
Protein FAM162A (FAM162A) LDTP10056 80.45  LDD1753 
Protein FAM177A1 (FAM177A1) LDTP15398 29.65  LDD1753 
Protein FAM3C (FAM3C) LDTP09773 38.05  LDD1753 
Protein jagunal homolog 1 (JAGN1) LDTP08904 47.18  LDD1753 
Protein LYRIC (MTDH) LDTP08224 33.13  LDD1753 
Protein NCBP2AS2 (NCBP2AS2) LDTP19472 30.06  LDD1753 
Protein PET100 homolog, mitochondrial (PET100) LDTP14618 42.22  LDD1753 
Protein SET (SET) LDTP05277 18.51  LDD1753 
Protein SYS1 homolog (SYS1) LDTP08796 45.89  LDD1753 
Protein YIF1A (YIF1A) LDTP01494 43.71  LDD1753 
Protein YIF1B (YIF1B) LDTP06948 57.28  LDD1753 
Protein YIPF4 (YIPF4) LDTP11167 16.22  LDD1753 
Receptor expression-enhancing protein 2 (REEP2) LDTP11113 30.27  LDD1753 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 30.91  LDD1753 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 18.00  LDD1753 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 24.08  LDD1753 
Regulator of microtubule dynamics protein 2 (RMDN2) LDTP10567 30.06  LDD1753 
Reticulocalbin-2 (RCN2) LDTP06097 17.27  LDD1753 
Reticulon-2 (RTN2) LDTP01167 37.53  LDD1753 
Reticulon-3 (RTN3) LDTP01522 62.25  LDD1753 
Reticulon-4 (RTN4) LDTP12412 44.02  LDD1753 
RUS family member 1 (RUSF1) LDTP10357 21.86  LDD1753 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 42.22  LDD1753 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 29.65  LDD1753 
Small integral membrane protein 12 (SMIM12) LDTP19859 30.48  LDD1753 
Small ribosomal subunit protein bS6m (MRPS6) LDTP05178 43.71  LDD1753 
Spermatogenesis-defective protein 39 homolog (VIPAS39) LDTP12091 20.68  LDD1753 
Synaptogyrin-2 (SYNGR2) LDTP00859 39.40  LDD1753 
Syntaxin-10 (STX10) LDTP00986 46.85  LDD1753 
Syntaxin-18 (STX18) LDTP13086 68.59  LDD1753 
Syntaxin-7 (STX7) LDTP00632 16.11  LDD1753 
Testis-expressed protein 264 (TEX264) LDTP14259 34.54  LDD1753 
Tetraspanin-6 (TSPAN6) LDTP14458 60.13  LDD1753 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 18.51  LDD1753 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 23.92  LDD1753 
Thioredoxin domain-containing protein 15 (TXNDC15) LDTP10442 33.82  LDD1753 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 35.51  LDD1753 
TraB domain-containing protein (TRABD) LDTP19963 34.54  LDD1753 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 25.46  LDD1753 
Transducin beta-like protein 2 (TBL2) LDTP16285 21.86  LDD1753 
Translocon-associated protein subunit delta (SSR4) LDTP04425 18.25  LDD1753 
Translocon-associated protein subunit gamma (SSR3) LDTP16250 19.56  LDD1753 
Transmembrane emp24 domain-containing protein 5 (TMED5) LDTP13967 18.77  LDD1753 
Transmembrane protein 209 (TMEM209) LDTP18272 25.99  LDD1753 
Transmembrane protein 35B (TMEM35B) LDTP19785 42.81  LDD1753 
Trophoblast glycoprotein (TPBG) LDTP05960 19.29  LDD1753 
Tumor necrosis factor alpha-induced protein 8 (TNFAIP8) LDTP01577 29.65  LDD1753 
Tumor protein D52 (TPD52) LDTP04703 25.46  LDD1753 
Tumor protein D54 (TPD52L2) LDTP00759 16.68  LDD1753 
U2 small nuclear ribonucleoprotein A' (SNRPA1) LDTP02365 19.84  LDD1753 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 59.71  LDD1753 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 86.22  LDD1753 
Uncharacterized protein KIAA2013 (KIAA2013) LDTP17652 16.34  LDD1753 
Vacuolar ATPase assembly integral membrane protein VMA21 (VMA21) LDTP06808 24.59  LDD1753 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 38.05  LDD1753 
Vimentin (VIM) LDTP02297 23.59  LDD1753 
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⏷ Show the Full List of 139 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1753 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587