Details of the Target

General Information of Target

Target ID LDTP10144
Target Name Phosphatidate cytidylyltransferase, mitochondrial (TAMM41)
Gene Name TAMM41
Gene ID 132001
Synonyms
C3orf31; Phosphatidate cytidylyltransferase, mitochondrial; EC 2.7.7.41; CDP-diacylglycerol synthase; CDP-DAG synthase; Mitochondrial translocator assembly and maintenance protein 41 homolog; TAM41
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MATELQCPDSMPCHNQQVNSASTPSPEQLRPGDLILDHAGGNRASRAKVILLTGYAHSSL
PAELDSGACGGSSLNSEGNSGSGDSSSYDAPAGNSFLEDCELSRQIGAQLKLLPMNDQIR
ELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGYKYEGVKFEKGNC
GVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIYRRKVLLMYPI
LSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTH
FGQKYFGTD
Target Bioclass
Enzyme
Family
TAM41 family
Subcellular location
Mitochondrion inner membrane
Function Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
Uniprot ID
Q96BW9
Ensemble ID
ENST00000273037.9
HGNC ID
HGNC:25187

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 12 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		12.96  LDD0402  [1]
STPyne
 Probe Info  		K15(2.00)  LDD2217  [2]
DBIA
 Probe Info  		C103(1.84)  LDD3319  [3]
ATP probe
 Probe Info  		K136(0.00); K139(0.00)  LDD0199  [4]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [5]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [6]
JW-RF-010
 Probe Info  		C285(0.00); C103(0.00)  LDD0026  [7]
IPM
 Probe Info  		N.A.  LDD2156  [8]
Acrolein
 Probe Info  		N.A.  LDD0217  [9]
Methacrolein
 Probe Info  		N.A.  LDD0218  [9]
AOyne
 Probe Info  		14.80  LDD0443  [10]
NAIA_5
 Probe Info  		N.A.  LDD2223  [11]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C056
 Probe Info  		19.03  LDD1753  [12]
VE-P
 Probe Info  		N.A.  LDD0396  [13]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C103(0.78)  LDD0812  [14]
 LDCM0215  AC10 HEK-293T C103(1.01)  LDD0813  [14]
 LDCM0216  AC100 HEK-293T C103(1.07)  LDD0814  [14]
 LDCM0217  AC101 HEK-293T C103(1.01)  LDD0815  [14]
 LDCM0218  AC102 HEK-293T C103(0.99)  LDD0816  [14]
 LDCM0219  AC103 HEK-293T C103(1.12)  LDD0817  [14]
 LDCM0220  AC104 HEK-293T C103(1.26)  LDD0818  [14]
 LDCM0221  AC105 HEK-293T C103(0.95)  LDD0819  [14]
 LDCM0222  AC106 HEK-293T C103(0.87)  LDD0820  [14]
 LDCM0223  AC107 HEK-293T C103(0.99)  LDD0821  [14]
 LDCM0224  AC108 HEK-293T C103(1.07)  LDD0822  [14]
 LDCM0225  AC109 HEK-293T C103(1.19)  LDD0823  [14]
 LDCM0226  AC11 HEK-293T C103(0.99)  LDD0824  [14]
 LDCM0227  AC110 HEK-293T C103(0.96)  LDD0825  [14]
 LDCM0228  AC111 HEK-293T C103(0.74)  LDD0826  [14]
 LDCM0229  AC112 HEK-293T C103(0.93)  LDD0827  [14]
 LDCM0230  AC113 HEK-293T C103(0.95)  LDD0828  [14]
 LDCM0231  AC114 HEK-293T C103(1.06)  LDD0829  [14]
 LDCM0232  AC115 HEK-293T C103(1.06)  LDD0830  [14]
 LDCM0233  AC116 HEK-293T C103(0.97)  LDD0831  [14]
 LDCM0234  AC117 HEK-293T C103(1.05)  LDD0832  [14]
 LDCM0235  AC118 HEK-293T C103(1.09)  LDD0833  [14]
 LDCM0236  AC119 HEK-293T C103(1.11)  LDD0834  [14]
 LDCM0237  AC12 HEK-293T C103(1.18)  LDD0835  [14]
 LDCM0238  AC120 HEK-293T C103(0.98)  LDD0836  [14]
 LDCM0239  AC121 HEK-293T C103(0.92)  LDD0837  [14]
 LDCM0240  AC122 HEK-293T C103(0.86)  LDD0838  [14]
 LDCM0241  AC123 HEK-293T C103(0.94)  LDD0839  [14]
 LDCM0242  AC124 HEK-293T C103(1.04)  LDD0840  [14]
 LDCM0243  AC125 HEK-293T C103(0.94)  LDD0841  [14]
 LDCM0244  AC126 HEK-293T C103(0.77)  LDD0842  [14]
 LDCM0245  AC127 HEK-293T C103(0.71)  LDD0843  [14]
 LDCM0246  AC128 HEK-293T C103(0.76)  LDD0844  [14]
 LDCM0247  AC129 HEK-293T C103(1.03)  LDD0845  [14]
 LDCM0249  AC130 HEK-293T C103(0.97)  LDD0847  [14]
 LDCM0250  AC131 HEK-293T C103(0.87)  LDD0848  [14]
 LDCM0251  AC132 HEK-293T C103(1.07)  LDD0849  [14]
 LDCM0252  AC133 HEK-293T C103(1.00)  LDD0850  [14]
 LDCM0253  AC134 HEK-293T C103(1.08)  LDD0851  [14]
 LDCM0254  AC135 HEK-293T C103(0.93)  LDD0852  [14]
 LDCM0255  AC136 HEK-293T C103(0.81)  LDD0853  [14]
 LDCM0256  AC137 HEK-293T C103(0.97)  LDD0854  [14]
 LDCM0257  AC138 HEK-293T C103(0.83)  LDD0855  [14]
 LDCM0258  AC139 HEK-293T C103(0.95)  LDD0856  [14]
 LDCM0259  AC14 HEK-293T C103(1.05)  LDD0857  [14]
 LDCM0260  AC140 HEK-293T C103(0.92)  LDD0858  [14]
 LDCM0261  AC141 HEK-293T C103(0.94)  LDD0859  [14]
 LDCM0262  AC142 HEK-293T C103(1.02)  LDD0860  [14]
 LDCM0263  AC143 HEK-293T C103(0.81)  LDD0861  [14]
 LDCM0264  AC144 HEK-293T C103(0.98)  LDD0862  [14]
 LDCM0265  AC145 HEK-293T C103(0.82)  LDD0863  [14]
 LDCM0266  AC146 HEK-293T C103(0.80)  LDD0864  [14]
 LDCM0267  AC147 HEK-293T C103(0.78)  LDD0865  [14]
 LDCM0268  AC148 HEK-293T C103(0.80)  LDD0866  [14]
 LDCM0269  AC149 HEK-293T C103(0.86)  LDD0867  [14]
 LDCM0270  AC15 HEK-293T C103(1.26)  LDD0868  [14]
 LDCM0271  AC150 HEK-293T C103(0.95)  LDD0869  [14]
 LDCM0272  AC151 HEK-293T C103(0.95)  LDD0870  [14]
 LDCM0273  AC152 HEK-293T C103(0.86)  LDD0871  [14]
 LDCM0274  AC153 HEK-293T C103(1.02)  LDD0872  [14]
 LDCM0621  AC154 HEK-293T C103(1.13)  LDD2162  [14]
 LDCM0622  AC155 HEK-293T C103(0.74)  LDD2163  [14]
 LDCM0623  AC156 HEK-293T C103(0.77)  LDD2164  [14]
 LDCM0624  AC157 HEK-293T C103(0.60)  LDD2165  [14]
 LDCM0276  AC17 HEK-293T C103(1.07)  LDD0874  [14]
 LDCM0277  AC18 HEK-293T C103(1.11)  LDD0875  [14]
 LDCM0278  AC19 HEK-293T C103(1.21)  LDD0876  [14]
 LDCM0279  AC2 HEK-293T C103(1.08)  LDD0877  [14]
 LDCM0280  AC20 HEK-293T C103(1.02)  LDD0878  [14]
 LDCM0281  AC21 HEK-293T C103(1.22)  LDD0879  [14]
 LDCM0282  AC22 HEK-293T C103(1.15)  LDD0880  [14]
 LDCM0283  AC23 HEK-293T C103(0.92)  LDD0881  [14]
 LDCM0284  AC24 HEK-293T C103(1.04)  LDD0882  [14]
 LDCM0285  AC25 HEK-293T C103(1.07)  LDD0883  [14]
 LDCM0286  AC26 HEK-293T C103(1.12)  LDD0884  [14]
 LDCM0287  AC27 HEK-293T C103(1.02)  LDD0885  [14]
 LDCM0288  AC28 HEK-293T C103(1.21)  LDD0886  [14]
 LDCM0289  AC29 HEK-293T C103(1.11)  LDD0887  [14]
 LDCM0290  AC3 HEK-293T C103(0.95)  LDD0888  [14]
 LDCM0291  AC30 HEK-293T C103(1.21)  LDD0889  [14]
 LDCM0292  AC31 HEK-293T C103(0.89)  LDD0890  [14]
 LDCM0293  AC32 HEK-293T C103(1.12)  LDD0891  [14]
 LDCM0294  AC33 HEK-293T C103(1.18)  LDD0892  [14]
 LDCM0295  AC34 HEK-293T C103(1.16)  LDD0893  [14]
 LDCM0296  AC35 HEK-293T C103(0.88)  LDD0894  [14]
 LDCM0297  AC36 HEK-293T C103(0.83)  LDD0895  [14]
 LDCM0298  AC37 HEK-293T C103(1.00)  LDD0896  [14]
 LDCM0299  AC38 HEK-293T C103(1.10)  LDD0897  [14]
 LDCM0300  AC39 HEK-293T C103(0.78)  LDD0898  [14]
 LDCM0301  AC4 HEK-293T C103(1.04)  LDD0899  [14]
 LDCM0302  AC40 HEK-293T C103(1.60)  LDD0900  [14]
 LDCM0303  AC41 HEK-293T C103(1.00)  LDD0901  [14]
 LDCM0304  AC42 HEK-293T C103(1.20)  LDD0902  [14]
 LDCM0305  AC43 HEK-293T C103(1.31)  LDD0903  [14]
 LDCM0306  AC44 HEK-293T C103(1.38)  LDD0904  [14]
 LDCM0307  AC45 HEK-293T C103(0.98)  LDD0905  [14]
 LDCM0308  AC46 HEK-293T C103(1.03)  LDD0906  [14]
 LDCM0309  AC47 HEK-293T C103(0.88)  LDD0907  [14]
 LDCM0310  AC48 HEK-293T C103(0.96)  LDD0908  [14]
 LDCM0311  AC49 HEK-293T C103(1.01)  LDD0909  [14]
 LDCM0312  AC5 HEK-293T C103(1.12)  LDD0910  [14]
 LDCM0313  AC50 HEK-293T C103(0.97)  LDD0911  [14]
 LDCM0314  AC51 HEK-293T C103(0.98)  LDD0912  [14]
 LDCM0315  AC52 HEK-293T C103(1.20)  LDD0913  [14]
 LDCM0316  AC53 HEK-293T C103(1.04)  LDD0914  [14]
 LDCM0317  AC54 HEK-293T C103(1.15)  LDD0915  [14]
 LDCM0318  AC55 HEK-293T C103(1.09)  LDD0916  [14]
 LDCM0319  AC56 HEK-293T C103(1.14)  LDD0917  [14]
 LDCM0320  AC57 HEK-293T C103(1.03)  LDD0918  [14]
 LDCM0321  AC58 HEK-293T C103(1.16)  LDD0919  [14]
 LDCM0322  AC59 HEK-293T C103(1.06)  LDD0920  [14]
 LDCM0323  AC6 HEK-293T C103(1.11)  LDD0921  [14]
 LDCM0324  AC60 HEK-293T C103(0.73)  LDD0922  [14]
 LDCM0325  AC61 HEK-293T C103(0.89)  LDD0923  [14]
 LDCM0326  AC62 HEK-293T C103(1.06)  LDD0924  [14]
 LDCM0327  AC63 HEK-293T C103(1.14)  LDD0925  [14]
 LDCM0328  AC64 HEK-293T C103(1.02)  LDD0926  [14]
 LDCM0329  AC65 HEK-293T C103(1.07)  LDD0927  [14]
 LDCM0330  AC66 HEK-293T C103(1.07)  LDD0928  [14]
 LDCM0331  AC67 HEK-293T C103(1.13)  LDD0929  [14]
 LDCM0332  AC68 HEK-293T C103(1.02)  LDD0930  [14]
 LDCM0333  AC69 HEK-293T C103(0.96)  LDD0931  [14]
 LDCM0334  AC7 HEK-293T C103(1.10)  LDD0932  [14]
 LDCM0335  AC70 HEK-293T C103(1.18)  LDD0933  [14]
 LDCM0336  AC71 HEK-293T C103(1.10)  LDD0934  [14]
 LDCM0337  AC72 HEK-293T C103(1.03)  LDD0935  [14]
 LDCM0338  AC73 HEK-293T C103(0.84)  LDD0936  [14]
 LDCM0339  AC74 HEK-293T C103(1.00)  LDD0937  [14]
 LDCM0340  AC75 HEK-293T C103(1.12)  LDD0938  [14]
 LDCM0341  AC76 HEK-293T C103(0.95)  LDD0939  [14]
 LDCM0342  AC77 HEK-293T C103(0.98)  LDD0940  [14]
 LDCM0343  AC78 HEK-293T C103(0.99)  LDD0941  [14]
 LDCM0344  AC79 HEK-293T C103(0.95)  LDD0942  [14]
 LDCM0345  AC8 HEK-293T C103(1.20)  LDD0943  [14]
 LDCM0346  AC80 HEK-293T C103(1.14)  LDD0944  [14]
 LDCM0347  AC81 HEK-293T C103(1.13)  LDD0945  [14]
 LDCM0348  AC82 HEK-293T C103(1.22)  LDD0946  [14]
 LDCM0349  AC83 HEK-293T C103(1.01)  LDD0947  [14]
 LDCM0350  AC84 HEK-293T C103(1.31)  LDD0948  [14]
 LDCM0351  AC85 HEK-293T C103(1.17)  LDD0949  [14]
 LDCM0352  AC86 HEK-293T C103(1.15)  LDD0950  [14]
 LDCM0353  AC87 HEK-293T C103(1.13)  LDD0951  [14]
 LDCM0354  AC88 HEK-293T C103(1.25)  LDD0952  [14]
 LDCM0355  AC89 HEK-293T C103(1.26)  LDD0953  [14]
 LDCM0357  AC90 HEK-293T C103(1.15)  LDD0955  [14]
 LDCM0358  AC91 HEK-293T C103(0.93)  LDD0956  [14]
 LDCM0359  AC92 HEK-293T C103(1.23)  LDD0957  [14]
 LDCM0360  AC93 HEK-293T C103(0.99)  LDD0958  [14]
 LDCM0361  AC94 HEK-293T C103(1.17)  LDD0959  [14]
 LDCM0362  AC95 HEK-293T C103(1.15)  LDD0960  [14]
 LDCM0363  AC96 HEK-293T C103(1.26)  LDD0961  [14]
 LDCM0364  AC97 HEK-293T C103(1.14)  LDD0962  [14]
 LDCM0365  AC98 HEK-293T C103(0.89)  LDD0963  [14]
 LDCM0366  AC99 HEK-293T C103(1.09)  LDD0964  [14]
 LDCM0248  AKOS034007472 HEK-293T C103(1.18)  LDD0846  [14]
 LDCM0356  AKOS034007680 HEK-293T C103(1.13)  LDD0954  [14]
 LDCM0275  AKOS034007705 HEK-293T C103(1.20)  LDD0873  [14]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [9]
 LDCM0367  CL1 HEK-293T C103(0.72)  LDD0965  [14]
 LDCM0368  CL10 HEK-293T C103(0.81)  LDD0966  [14]
 LDCM0369  CL100 HEK-293T C103(0.97)  LDD0967  [14]
 LDCM0370  CL101 HEK-293T C103(1.20)  LDD0968  [14]
 LDCM0371  CL102 HEK-293T C103(1.07)  LDD0969  [14]
 LDCM0372  CL103 HEK-293T C103(1.22)  LDD0970  [14]
 LDCM0373  CL104 HEK-293T C103(1.15)  LDD0971  [14]
 LDCM0374  CL105 HEK-293T C103(0.97)  LDD0972  [14]
 LDCM0375  CL106 HEK-293T C103(1.04)  LDD0973  [14]
 LDCM0376  CL107 HEK-293T C103(1.03)  LDD0974  [14]
 LDCM0377  CL108 HEK-293T C103(1.08)  LDD0975  [14]
 LDCM0378  CL109 HEK-293T C103(1.08)  LDD0976  [14]
 LDCM0379  CL11 HEK-293T C103(0.78)  LDD0977  [14]
 LDCM0380  CL110 HEK-293T C103(1.02)  LDD0978  [14]
 LDCM0381  CL111 HEK-293T C103(1.00)  LDD0979  [14]
 LDCM0382  CL112 HEK-293T C103(1.10)  LDD0980  [14]
 LDCM0383  CL113 HEK-293T C103(1.19)  LDD0981  [14]
 LDCM0384  CL114 HEK-293T C103(0.96)  LDD0982  [14]
 LDCM0385  CL115 HEK-293T C103(1.01)  LDD0983  [14]
 LDCM0386  CL116 HEK-293T C103(1.07)  LDD0984  [14]
 LDCM0387  CL117 HEK-293T C103(0.95)  LDD0985  [14]
 LDCM0388  CL118 HEK-293T C103(0.76)  LDD0986  [14]
 LDCM0389  CL119 HEK-293T C103(1.10)  LDD0987  [14]
 LDCM0390  CL12 HEK-293T C103(0.56)  LDD0988  [14]
 LDCM0391  CL120 HEK-293T C103(1.27)  LDD0989  [14]
 LDCM0392  CL121 HEK-293T C103(1.07)  LDD0990  [14]
 LDCM0393  CL122 HEK-293T C103(1.18)  LDD0991  [14]
 LDCM0394  CL123 HEK-293T C103(0.83)  LDD0992  [14]
 LDCM0395  CL124 HEK-293T C103(1.05)  LDD0993  [14]
 LDCM0396  CL125 HEK-293T C103(0.96)  LDD0994  [14]
 LDCM0397  CL126 HEK-293T C103(1.01)  LDD0995  [14]
 LDCM0398  CL127 HEK-293T C103(1.14)  LDD0996  [14]
 LDCM0399  CL128 HEK-293T C103(1.03)  LDD0997  [14]
 LDCM0400  CL13 HEK-293T C103(0.74)  LDD0998  [14]
 LDCM0401  CL14 HEK-293T C103(0.81)  LDD0999  [14]
 LDCM0402  CL15 HEK-293T C103(0.49)  LDD1000  [14]
 LDCM0403  CL16 HEK-293T C103(1.08)  LDD1001  [14]
 LDCM0404  CL17 HEK-293T C103(0.74)  LDD1002  [14]
 LDCM0405  CL18 HEK-293T C103(1.02)  LDD1003  [14]
 LDCM0406  CL19 HEK-293T C103(1.06)  LDD1004  [14]
 LDCM0407  CL2 HEK-293T C103(0.79)  LDD1005  [14]
 LDCM0408  CL20 HEK-293T C103(1.01)  LDD1006  [14]
 LDCM0409  CL21 HEK-293T C103(0.79)  LDD1007  [14]
 LDCM0410  CL22 HEK-293T C103(0.97)  LDD1008  [14]
 LDCM0411  CL23 HEK-293T C103(0.85)  LDD1009  [14]
 LDCM0412  CL24 HEK-293T C103(1.06)  LDD1010  [14]
 LDCM0413  CL25 HEK-293T C103(0.93)  LDD1011  [14]
 LDCM0414  CL26 HEK-293T C103(0.80)  LDD1012  [14]
 LDCM0415  CL27 HEK-293T C103(0.98)  LDD1013  [14]
 LDCM0416  CL28 HEK-293T C103(0.79)  LDD1014  [14]
 LDCM0417  CL29 HEK-293T C103(0.86)  LDD1015  [14]
 LDCM0418  CL3 HEK-293T C103(0.73)  LDD1016  [14]
 LDCM0419  CL30 HEK-293T C103(0.97)  LDD1017  [14]
 LDCM0420  CL31 HEK-293T C103(0.98)  LDD1018  [14]
 LDCM0421  CL32 HEK-293T C103(0.93)  LDD1019  [14]
 LDCM0422  CL33 HEK-293T C103(0.59)  LDD1020  [14]
 LDCM0423  CL34 HEK-293T C103(0.84)  LDD1021  [14]
 LDCM0424  CL35 HEK-293T C103(1.06)  LDD1022  [14]
 LDCM0425  CL36 HEK-293T C103(0.62)  LDD1023  [14]
 LDCM0426  CL37 HEK-293T C103(0.91)  LDD1024  [14]
 LDCM0428  CL39 HEK-293T C103(1.02)  LDD1026  [14]
 LDCM0429  CL4 HEK-293T C103(0.55)  LDD1027  [14]
 LDCM0430  CL40 HEK-293T C103(1.06)  LDD1028  [14]
 LDCM0431  CL41 HEK-293T C103(0.91)  LDD1029  [14]
 LDCM0432  CL42 HEK-293T C103(1.19)  LDD1030  [14]
 LDCM0433  CL43 HEK-293T C103(1.08)  LDD1031  [14]
 LDCM0434  CL44 HEK-293T C103(1.06)  LDD1032  [14]
 LDCM0435  CL45 HEK-293T C103(0.96)  LDD1033  [14]
 LDCM0436  CL46 HEK-293T C103(1.15)  LDD1034  [14]
 LDCM0437  CL47 HEK-293T C103(1.14)  LDD1035  [14]
 LDCM0438  CL48 HEK-293T C103(1.02)  LDD1036  [14]
 LDCM0439  CL49 HEK-293T C103(1.19)  LDD1037  [14]
 LDCM0440  CL5 HEK-293T C103(0.75)  LDD1038  [14]
 LDCM0441  CL50 HEK-293T C103(0.94)  LDD1039  [14]
 LDCM0442  CL51 HEK-293T C103(0.90)  LDD1040  [14]
 LDCM0443  CL52 HEK-293T C103(1.03)  LDD1041  [14]
 LDCM0444  CL53 HEK-293T C103(1.15)  LDD1042  [14]
 LDCM0445  CL54 HEK-293T C103(0.78)  LDD1043  [14]
 LDCM0446  CL55 HEK-293T C103(1.17)  LDD1044  [14]
 LDCM0447  CL56 HEK-293T C103(0.96)  LDD1045  [14]
 LDCM0448  CL57 HEK-293T C103(0.93)  LDD1046  [14]
 LDCM0449  CL58 HEK-293T C103(1.08)  LDD1047  [14]
 LDCM0450  CL59 HEK-293T C103(1.22)  LDD1048  [14]
 LDCM0451  CL6 HEK-293T C103(0.61)  LDD1049  [14]
 LDCM0452  CL60 HEK-293T C103(1.11)  LDD1050  [14]
 LDCM0453  CL61 HEK-293T C103(1.15)  LDD1051  [14]
 LDCM0454  CL62 HEK-293T C103(1.06)  LDD1052  [14]
 LDCM0455  CL63 HEK-293T C103(1.11)  LDD1053  [14]
 LDCM0456  CL64 HEK-293T C103(1.01)  LDD1054  [14]
 LDCM0457  CL65 HEK-293T C103(1.15)  LDD1055  [14]
 LDCM0458  CL66 HEK-293T C103(0.81)  LDD1056  [14]
 LDCM0459  CL67 HEK-293T C103(0.94)  LDD1057  [14]
 LDCM0460  CL68 HEK-293T C103(0.79)  LDD1058  [14]
 LDCM0461  CL69 HEK-293T C103(0.88)  LDD1059  [14]
 LDCM0462  CL7 HEK-293T C103(0.68)  LDD1060  [14]
 LDCM0463  CL70 HEK-293T C103(0.97)  LDD1061  [14]
 LDCM0464  CL71 HEK-293T C103(0.94)  LDD1062  [14]
 LDCM0465  CL72 HEK-293T C103(1.05)  LDD1063  [14]
 LDCM0466  CL73 HEK-293T C103(0.82)  LDD1064  [14]
 LDCM0467  CL74 HEK-293T C103(1.00)  LDD1065  [14]
 LDCM0469  CL76 HEK-293T C103(1.22); C285(1.06)  LDD1672  [15]
 LDCM0470  CL77 HEK-293T C103(1.08); C285(0.95)  LDD1673  [15]
 LDCM0471  CL78 HEK-293T C103(0.97); C285(1.09)  LDD1674  [15]
 LDCM0472  CL79 HEK-293T C103(1.05); C285(1.05)  LDD1675  [15]
 LDCM0473  CL8 HEK-293T C103(0.76)  LDD1071  [14]
 LDCM0474  CL80 HEK-293T C103(1.14); C285(0.93)  LDD1677  [15]
 LDCM0475  CL81 HEK-293T C103(1.25); C285(0.92)  LDD1678  [15]
 LDCM0476  CL82 HEK-293T C103(1.08); C285(0.98)  LDD1679  [15]
 LDCM0477  CL83 HEK-293T C103(0.98); C285(1.10)  LDD1680  [15]
 LDCM0478  CL84 HEK-293T C103(1.11); C285(0.71)  LDD1681  [15]
 LDCM0479  CL85 HEK-293T C103(1.08)  LDD1682  [15]
 LDCM0480  CL86 HEK-293T C103(1.17); C285(1.34)  LDD1683  [15]
 LDCM0481  CL87 HEK-293T C103(1.04); C285(1.04)  LDD1684  [15]
 LDCM0482  CL88 HEK-293T C103(1.19); C285(1.16)  LDD1685  [15]
 LDCM0483  CL89 HEK-293T C103(1.17); C285(1.14)  LDD1686  [15]
 LDCM0484  CL9 HEK-293T C103(0.87)  LDD1082  [14]
 LDCM0485  CL90 HEK-293T C103(0.87); C285(0.89)  LDD1688  [15]
 LDCM0486  CL91 HEK-293T C103(0.99)  LDD1084  [14]
 LDCM0487  CL92 HEK-293T C103(0.77)  LDD1085  [14]
 LDCM0488  CL93 HEK-293T C103(0.88)  LDD1086  [14]
 LDCM0489  CL94 HEK-293T C103(1.11)  LDD1087  [14]
 LDCM0490  CL95 HEK-293T C103(1.03)  LDD1088  [14]
 LDCM0491  CL96 HEK-293T C103(1.09)  LDD1089  [14]
 LDCM0492  CL97 HEK-293T C103(1.03)  LDD1090  [14]
 LDCM0493  CL98 HEK-293T C103(0.86)  LDD1091  [14]
 LDCM0494  CL99 HEK-293T C103(0.95)  LDD1092  [14]
 LDCM0495  E2913 HEK-293T C103(0.98); C285(1.04)  LDD1698  [15]
 LDCM0625  F8 Ramos C285(0.81)  LDD2187  [16]
 LDCM0572  Fragment10 Ramos C285(1.14)  LDD2189  [16]
 LDCM0573  Fragment11 Ramos C285(1.99)  LDD2190  [16]
 LDCM0574  Fragment12 Ramos C285(1.35)  LDD2191  [16]
 LDCM0575  Fragment13 Ramos C285(0.77)  LDD2192  [16]
 LDCM0576  Fragment14 Ramos C285(1.38)  LDD2193  [16]
 LDCM0579  Fragment20 Ramos C285(1.49)  LDD2194  [16]
 LDCM0580  Fragment21 Ramos C285(1.18)  LDD2195  [16]
 LDCM0582  Fragment23 Ramos C285(1.32)  LDD2196  [16]
 LDCM0578  Fragment27 Ramos C285(1.08)  LDD2197  [16]
 LDCM0586  Fragment28 Ramos C285(0.74)  LDD2198  [16]
 LDCM0588  Fragment30 Ramos C285(0.95)  LDD2199  [16]
 LDCM0589  Fragment31 Ramos C285(1.17)  LDD2200  [16]
 LDCM0590  Fragment32 Ramos C285(0.84)  LDD2201  [16]
 LDCM0468  Fragment33 HEK-293T C103(0.81)  LDD1066  [14]
 LDCM0596  Fragment38 Ramos C285(1.07)  LDD2203  [16]
 LDCM0566  Fragment4 Ramos C285(0.73)  LDD2184  [16]
 LDCM0427  Fragment51 HEK-293T C103(0.74)  LDD1025  [14]
 LDCM0610  Fragment52 Ramos C285(0.98)  LDD2204  [16]
 LDCM0614  Fragment56 Ramos C285(0.78)  LDD2205  [16]
 LDCM0569  Fragment7 Ramos C285(0.95)  LDD2186  [16]
 LDCM0571  Fragment9 Ramos C285(2.25)  LDD2188  [16]
 LDCM0015  HNE MDA-MB-231 C285(1.06)  LDD0346  [16]
 LDCM0107  IAA HeLa N.A.  LDD0221  [9]
 LDCM0022  KB02 HEK-293T C285(0.99)  LDD1492  [15]
 LDCM0023  KB03 HEK-293T C285(0.99)  LDD1497  [15]
 LDCM0024  KB05 MEWO C103(1.84)  LDD3319  [3]
 LDCM0109  NEM HeLa N.A.  LDD0224  [9]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Glucose-6-phosphate isomerase (GPI) GPI family P06744

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Global profiling of lysine reactivity and ligandability in the human proteome. Nat Chem. 2017 Dec;9(12):1181-1190. doi: 10.1038/nchem.2826. Epub 2017 Jul 31.
3 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
4 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
5 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
6 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
7 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
8 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
9 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
10 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
11 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
12 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
13 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
14 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
15 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
16 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578