Details of the Target

General Information of Target

Target ID LDTP14205
Target Name Neuroplastin (NPTN)
Gene Name NPTN
Gene ID 27020
Synonyms
SDFR1; SDR1; Neuroplastin; Stromal cell-derived receptor 1; SDR-1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPSWIGAVILPLLGLLLSLPAGADVKARSCGEVRQAYGAKGFSLADIPYQEIAGEHLRIC
PQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSL
NDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQY
HFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVSKVSP
TPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDTEWNLFIDAMLLVAE
RLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPENF
NTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDESVTAGTSNEE
ECWNGHSKARYLPEIMNDGLTNQINNPEVDVDITRPDTFIRQQIMALRVMTNKLKNAYNG
NDVNFQDTSDESSGSGSGSGCMDDVCPTEFEFVTTEAPAVDPDRREVDSSAAQRGHSLLS
WSLTCIVLALQRLCR
Target Bioclass
Immunoglobulin
Subcellular location
Postsynaptic density; Cell membrane
Function
Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity. Also acts as a chaperone for ATP2B1; stabilizes ATP2B1 and increases its ATPase activity. Promotes localization of XKR8 at the cell membrane.
Uniprot ID
Q9Y639
Ensemble ID
ENST00000345330.9
HGNC ID
HGNC:17867

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 9 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K244(3.56)  LDD0277  [1]
OPA-S-S-alkyne
 Probe Info  		K260(1.00); K244(8.84)  LDD3494  [2]
DBIA
 Probe Info  		C259(1.44)  LDD3335  [3]
BTD
 Probe Info  		C259(0.88)  LDD2089  [4]
Acrolein
 Probe Info  		N.A.  LDD0221  [5]
4-Iodoacetamidophenylacetylene
 Probe Info  		C218(0.00); C259(0.00)  LDD0038  [6]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [6]
Lodoacetamide azide
 Probe Info  		C218(0.00); C259(0.00)  LDD0037  [6]
NAIA_5
 Probe Info  		C218(0.00); C259(0.00)  LDD2223  [7]
PAL-AfBPP Probe
Click To Hide/Show 11 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C040
 Probe Info  		6.59  LDD1740  [8]
C055
 Probe Info  		18.13  LDD1752  [8]
C056
 Probe Info  		31.34  LDD1753  [8]
C287
 Probe Info  		10.41  LDD1957  [8]
C289
 Probe Info  		28.25  LDD1959  [8]
C296
 Probe Info  		11.31  LDD1966  [8]
C326
 Probe Info  		8.17  LDD1990  [8]
C343
 Probe Info  		12.64  LDD2005  [8]
C388
 Probe Info  		37.79  LDD2047  [8]
A-DA
 Probe Info  		2.98  LDD0145  [9]
OEA-DA
 Probe Info  		20.00  LDD0046  [10]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C259(0.76)  LDD2130  [4]
 LDCM0214  AC1 HEK-293T C259(1.49)  LDD1507  [11]
 LDCM0215  AC10 HEK-293T C259(1.06)  LDD1508  [11]
 LDCM0226  AC11 HEK-293T C259(1.03)  LDD1509  [11]
 LDCM0237  AC12 HEK-293T C259(1.16)  LDD1510  [11]
 LDCM0259  AC14 HEK-293T C259(0.96)  LDD1512  [11]
 LDCM0270  AC15 HEK-293T C259(1.04)  LDD1513  [11]
 LDCM0276  AC17 HEK-293T C259(1.45)  LDD1515  [11]
 LDCM0277  AC18 HEK-293T C259(1.00)  LDD1516  [11]
 LDCM0278  AC19 HEK-293T C259(1.40)  LDD1517  [11]
 LDCM0279  AC2 HEK-293T C259(0.95)  LDD1518  [11]
 LDCM0280  AC20 HEK-293T C259(1.09)  LDD1519  [11]
 LDCM0281  AC21 HEK-293T C259(1.21)  LDD1520  [11]
 LDCM0282  AC22 HEK-293T C259(1.05)  LDD1521  [11]
 LDCM0283  AC23 HEK-293T C259(0.94)  LDD1522  [11]
 LDCM0284  AC24 HEK-293T C259(1.40)  LDD1523  [11]
 LDCM0285  AC25 HEK-293T C259(1.10)  LDD1524  [11]
 LDCM0286  AC26 HEK-293T C259(1.02)  LDD1525  [11]
 LDCM0287  AC27 HEK-293T C259(1.36)  LDD1526  [11]
 LDCM0288  AC28 HEK-293T C259(1.15)  LDD1527  [11]
 LDCM0289  AC29 HEK-293T C259(1.07)  LDD1528  [11]
 LDCM0290  AC3 HEK-293T C259(1.23)  LDD1529  [11]
 LDCM0291  AC30 HEK-293T C259(1.05)  LDD1530  [11]
 LDCM0292  AC31 HEK-293T C259(0.96)  LDD1531  [11]
 LDCM0293  AC32 HEK-293T C259(0.86)  LDD1532  [11]
 LDCM0294  AC33 HEK-293T C259(1.05)  LDD1533  [11]
 LDCM0295  AC34 HEK-293T C259(1.06)  LDD1534  [11]
 LDCM0296  AC35 HEK-293T C259(1.24)  LDD1535  [11]
 LDCM0297  AC36 HEK-293T C259(1.14)  LDD1536  [11]
 LDCM0298  AC37 HEK-293T C259(0.93)  LDD1537  [11]
 LDCM0299  AC38 HEK-293T C259(0.85)  LDD1538  [11]
 LDCM0300  AC39 HEK-293T C259(0.95)  LDD1539  [11]
 LDCM0301  AC4 HEK-293T C259(1.06)  LDD1540  [11]
 LDCM0302  AC40 HEK-293T C259(1.00)  LDD1541  [11]
 LDCM0303  AC41 HEK-293T C259(1.43)  LDD1542  [11]
 LDCM0304  AC42 HEK-293T C259(1.18)  LDD1543  [11]
 LDCM0305  AC43 HEK-293T C259(1.23)  LDD1544  [11]
 LDCM0306  AC44 HEK-293T C259(1.18)  LDD1545  [11]
 LDCM0307  AC45 HEK-293T C259(1.17)  LDD1546  [11]
 LDCM0308  AC46 HEK-293T C259(1.19)  LDD1547  [11]
 LDCM0309  AC47 HEK-293T C259(1.04)  LDD1548  [11]
 LDCM0310  AC48 HEK-293T C259(1.42)  LDD1549  [11]
 LDCM0311  AC49 HEK-293T C259(1.53)  LDD1550  [11]
 LDCM0312  AC5 HEK-293T C259(1.14)  LDD1551  [11]
 LDCM0313  AC50 HEK-293T C259(1.00)  LDD1552  [11]
 LDCM0314  AC51 HEK-293T C259(1.05)  LDD1553  [11]
 LDCM0315  AC52 HEK-293T C259(1.07)  LDD1554  [11]
 LDCM0316  AC53 HEK-293T C259(1.19)  LDD1555  [11]
 LDCM0317  AC54 HEK-293T C259(0.78)  LDD1556  [11]
 LDCM0318  AC55 HEK-293T C259(1.18)  LDD1557  [11]
 LDCM0319  AC56 HEK-293T C259(0.86)  LDD1558  [11]
 LDCM0320  AC57 HEK-293T C259(1.30)  LDD1559  [11]
 LDCM0321  AC58 HEK-293T C259(1.12)  LDD1560  [11]
 LDCM0322  AC59 HEK-293T C259(1.10)  LDD1561  [11]
 LDCM0323  AC6 HEK-293T C259(0.81)  LDD1562  [11]
 LDCM0324  AC60 HEK-293T C259(1.09)  LDD1563  [11]
 LDCM0325  AC61 HEK-293T C259(0.96)  LDD1564  [11]
 LDCM0326  AC62 HEK-293T C259(0.90)  LDD1565  [11]
 LDCM0327  AC63 HEK-293T C259(1.15)  LDD1566  [11]
 LDCM0328  AC64 HEK-293T C259(0.88)  LDD1567  [11]
 LDCM0334  AC7 HEK-293T C259(1.02)  LDD1568  [11]
 LDCM0345  AC8 HEK-293T C259(0.98)  LDD1569  [11]
 LDCM0545  Acetamide MDA-MB-231 C259(0.96)  LDD2138  [4]
 LDCM0248  AKOS034007472 HEK-293T C259(1.16)  LDD1511  [11]
 LDCM0356  AKOS034007680 HEK-293T C259(1.42)  LDD1570  [11]
 LDCM0275  AKOS034007705 HEK-293T C259(0.90)  LDD1514  [11]
 LDCM0498  BS-3668 MDA-MB-231 C259(0.85)  LDD2091  [4]
 LDCM0367  CL1 HEK-293T C259(0.92)  LDD1571  [11]
 LDCM0368  CL10 HEK-293T C259(0.92)  LDD1572  [11]
 LDCM0369  CL100 HEK-293T C259(1.07)  LDD1573  [11]
 LDCM0370  CL101 HEK-293T C259(1.01)  LDD1574  [11]
 LDCM0371  CL102 HEK-293T C259(1.06)  LDD1575  [11]
 LDCM0372  CL103 HEK-293T C259(1.07)  LDD1576  [11]
 LDCM0373  CL104 HEK-293T C259(0.96)  LDD1577  [11]
 LDCM0374  CL105 HEK-293T C259(0.83)  LDD1578  [11]
 LDCM0375  CL106 HEK-293T C259(1.35)  LDD1579  [11]
 LDCM0376  CL107 HEK-293T C259(0.90)  LDD1580  [11]
 LDCM0377  CL108 HEK-293T C259(1.19)  LDD1581  [11]
 LDCM0378  CL109 HEK-293T C259(0.95)  LDD1582  [11]
 LDCM0379  CL11 HEK-293T C259(1.03)  LDD1583  [11]
 LDCM0380  CL110 HEK-293T C259(1.07)  LDD1584  [11]
 LDCM0381  CL111 HEK-293T C259(1.11)  LDD1585  [11]
 LDCM0382  CL112 HEK-293T C259(1.35)  LDD1586  [11]
 LDCM0383  CL113 HEK-293T C259(0.83)  LDD1587  [11]
 LDCM0384  CL114 HEK-293T C259(1.13)  LDD1588  [11]
 LDCM0385  CL115 HEK-293T C259(0.95)  LDD1589  [11]
 LDCM0386  CL116 HEK-293T C259(1.25)  LDD1590  [11]
 LDCM0387  CL117 HEK-293T C259(0.88)  LDD1591  [11]
 LDCM0388  CL118 HEK-293T C259(1.32)  LDD1592  [11]
 LDCM0389  CL119 HEK-293T C259(1.15)  LDD1593  [11]
 LDCM0390  CL12 HEK-293T C259(1.11)  LDD1594  [11]
 LDCM0391  CL120 HEK-293T C259(1.14)  LDD1595  [11]
 LDCM0392  CL121 HEK-293T C259(1.00)  LDD1596  [11]
 LDCM0393  CL122 HEK-293T C259(1.14)  LDD1597  [11]
 LDCM0394  CL123 HEK-293T C259(1.00)  LDD1598  [11]
 LDCM0395  CL124 HEK-293T C259(1.19)  LDD1599  [11]
 LDCM0396  CL125 HEK-293T C259(1.05)  LDD1600  [11]
 LDCM0397  CL126 HEK-293T C259(1.09)  LDD1601  [11]
 LDCM0398  CL127 HEK-293T C259(1.11)  LDD1602  [11]
 LDCM0399  CL128 HEK-293T C259(0.90)  LDD1603  [11]
 LDCM0400  CL13 HEK-293T C259(1.08)  LDD1604  [11]
 LDCM0401  CL14 HEK-293T C259(1.06)  LDD1605  [11]
 LDCM0402  CL15 HEK-293T C259(1.27)  LDD1606  [11]
 LDCM0403  CL16 HEK-293T C259(1.02)  LDD1607  [11]
 LDCM0404  CL17 HEK-293T C259(1.26)  LDD1608  [11]
 LDCM0405  CL18 HEK-293T C259(1.11)  LDD1609  [11]
 LDCM0406  CL19 HEK-293T C259(1.15)  LDD1610  [11]
 LDCM0407  CL2 HEK-293T C259(1.20)  LDD1611  [11]
 LDCM0408  CL20 HEK-293T C259(0.94)  LDD1612  [11]
 LDCM0409  CL21 HEK-293T C259(0.93)  LDD1613  [11]
 LDCM0410  CL22 HEK-293T C259(0.81)  LDD1614  [11]
 LDCM0411  CL23 HEK-293T C259(1.07)  LDD1615  [11]
 LDCM0412  CL24 HEK-293T C259(0.96)  LDD1616  [11]
 LDCM0413  CL25 HEK-293T C259(0.96)  LDD1617  [11]
 LDCM0414  CL26 HEK-293T C259(1.08)  LDD1618  [11]
 LDCM0415  CL27 HEK-293T C259(1.15)  LDD1619  [11]
 LDCM0416  CL28 HEK-293T C259(0.92)  LDD1620  [11]
 LDCM0417  CL29 HEK-293T C259(1.25)  LDD1621  [11]
 LDCM0418  CL3 HEK-293T C259(0.86)  LDD1622  [11]
 LDCM0419  CL30 HEK-293T C259(1.09)  LDD1623  [11]
 LDCM0420  CL31 HEK-293T C259(1.10)  LDD1624  [11]
 LDCM0421  CL32 HEK-293T C259(1.15)  LDD1625  [11]
 LDCM0422  CL33 HEK-293T C259(1.14)  LDD1626  [11]
 LDCM0423  CL34 HEK-293T C259(1.05)  LDD1627  [11]
 LDCM0424  CL35 HEK-293T C259(1.00)  LDD1628  [11]
 LDCM0425  CL36 HEK-293T C259(0.79)  LDD1629  [11]
 LDCM0426  CL37 HEK-293T C259(0.75)  LDD1630  [11]
 LDCM0428  CL39 HEK-293T C259(1.05)  LDD1632  [11]
 LDCM0429  CL4 HEK-293T C259(0.96)  LDD1633  [11]
 LDCM0430  CL40 HEK-293T C259(1.08)  LDD1634  [11]
 LDCM0431  CL41 HEK-293T C259(1.11)  LDD1635  [11]
 LDCM0432  CL42 HEK-293T C259(0.95)  LDD1636  [11]
 LDCM0433  CL43 HEK-293T C259(1.01)  LDD1637  [11]
 LDCM0434  CL44 HEK-293T C259(1.03)  LDD1638  [11]
 LDCM0435  CL45 HEK-293T C259(1.06)  LDD1639  [11]
 LDCM0436  CL46 HEK-293T C259(0.88)  LDD1640  [11]
 LDCM0437  CL47 HEK-293T C259(1.09)  LDD1641  [11]
 LDCM0438  CL48 HEK-293T C259(1.00)  LDD1642  [11]
 LDCM0439  CL49 HEK-293T C259(1.09)  LDD1643  [11]
 LDCM0440  CL5 HEK-293T C259(1.14)  LDD1644  [11]
 LDCM0441  CL50 HEK-293T C259(1.22)  LDD1645  [11]
 LDCM0443  CL52 HEK-293T C259(1.12)  LDD1646  [11]
 LDCM0444  CL53 HEK-293T C259(1.24)  LDD1647  [11]
 LDCM0445  CL54 HEK-293T C259(1.03)  LDD1648  [11]
 LDCM0446  CL55 HEK-293T C259(1.06)  LDD1649  [11]
 LDCM0447  CL56 HEK-293T C259(1.04)  LDD1650  [11]
 LDCM0448  CL57 HEK-293T C259(1.16)  LDD1651  [11]
 LDCM0449  CL58 HEK-293T C259(0.77)  LDD1652  [11]
 LDCM0450  CL59 HEK-293T C259(0.94)  LDD1653  [11]
 LDCM0451  CL6 HEK-293T C259(0.90)  LDD1654  [11]
 LDCM0452  CL60 HEK-293T C259(0.87)  LDD1655  [11]
 LDCM0453  CL61 HEK-293T C259(1.02)  LDD1656  [11]
 LDCM0454  CL62 HEK-293T C259(1.02)  LDD1657  [11]
 LDCM0455  CL63 HEK-293T C259(0.74)  LDD1658  [11]
 LDCM0456  CL64 HEK-293T C259(1.33)  LDD1659  [11]
 LDCM0457  CL65 HEK-293T C259(1.26)  LDD1660  [11]
 LDCM0458  CL66 HEK-293T C259(0.94)  LDD1661  [11]
 LDCM0459  CL67 HEK-293T C259(1.05)  LDD1662  [11]
 LDCM0460  CL68 HEK-293T C259(1.04)  LDD1663  [11]
 LDCM0461  CL69 HEK-293T C259(1.08)  LDD1664  [11]
 LDCM0462  CL7 HEK-293T C259(1.12)  LDD1665  [11]
 LDCM0463  CL70 HEK-293T C259(1.05)  LDD1666  [11]
 LDCM0464  CL71 HEK-293T C259(1.09)  LDD1667  [11]
 LDCM0465  CL72 HEK-293T C259(1.05)  LDD1668  [11]
 LDCM0466  CL73 HEK-293T C259(0.77)  LDD1669  [11]
 LDCM0467  CL74 HEK-293T C259(1.17)  LDD1670  [11]
 LDCM0469  CL76 HEK-293T C259(1.07)  LDD1672  [11]
 LDCM0470  CL77 HEK-293T C259(1.24)  LDD1673  [11]
 LDCM0471  CL78 HEK-293T C259(1.02)  LDD1674  [11]
 LDCM0472  CL79 HEK-293T C259(1.08)  LDD1675  [11]
 LDCM0473  CL8 HEK-293T C259(1.06)  LDD1676  [11]
 LDCM0474  CL80 HEK-293T C259(0.99)  LDD1677  [11]
 LDCM0475  CL81 HEK-293T C259(1.17)  LDD1678  [11]
 LDCM0476  CL82 HEK-293T C259(1.12)  LDD1679  [11]
 LDCM0477  CL83 HEK-293T C259(1.09)  LDD1680  [11]
 LDCM0478  CL84 HEK-293T C259(0.91)  LDD1681  [11]
 LDCM0479  CL85 HEK-293T C259(0.89)  LDD1682  [11]
 LDCM0480  CL86 HEK-293T C259(1.05)  LDD1683  [11]
 LDCM0481  CL87 HEK-293T C259(1.10)  LDD1684  [11]
 LDCM0482  CL88 HEK-293T C259(0.93)  LDD1685  [11]
 LDCM0483  CL89 HEK-293T C259(1.22)  LDD1686  [11]
 LDCM0484  CL9 HEK-293T C259(1.01)  LDD1687  [11]
 LDCM0485  CL90 HEK-293T C259(1.07)  LDD1688  [11]
 LDCM0486  CL91 HEK-293T C259(1.01)  LDD1689  [11]
 LDCM0487  CL92 HEK-293T C259(1.05)  LDD1690  [11]
 LDCM0488  CL93 HEK-293T C259(0.87)  LDD1691  [11]
 LDCM0489  CL94 HEK-293T C259(0.75)  LDD1692  [11]
 LDCM0490  CL95 HEK-293T C259(0.95)  LDD1693  [11]
 LDCM0491  CL96 HEK-293T C259(0.71)  LDD1694  [11]
 LDCM0492  CL97 HEK-293T C259(1.22)  LDD1695  [11]
 LDCM0493  CL98 HEK-293T C259(1.05)  LDD1696  [11]
 LDCM0494  CL99 HEK-293T C259(0.95)  LDD1697  [11]
 LDCM0495  E2913 HEK-293T C259(1.04)  LDD1698  [11]
 LDCM0468  Fragment33 HEK-293T C259(1.04)  LDD1671  [11]
 LDCM0427  Fragment51 HEK-293T C259(1.07)  LDD1631  [11]
 LDCM0107  IAA HeLa N.A.  LDD0221  [5]
 LDCM0022  KB02 HEK-293T C259(0.95)  LDD1492  [11]
 LDCM0023  KB03 HEK-293T C259(1.00)  LDD1497  [11]
 LDCM0024  KB05 MONO-MAC-6 C259(1.44)  LDD3335  [3]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C259(1.11)  LDD2121  [4]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C259(0.88)  LDD2089  [4]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C259(0.59)  LDD2150  [4]
 LDCM0084  Ro 48-8071 A-549 2.98  LDD0145  [9]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Huntingtin (HTT) Huntingtin family P42858
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cysteine-rich tail protein 1 (CYSRT1) CYSRT1 family A8MQ03

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun. 2024 Apr 8;15(1):2997. doi: 10.1038/s41467-024-47033-w.
Mass spectrometry data entry: PXD042888
3 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
4 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
5 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
6 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
7 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
8 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
9 A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells. Cell. 2015 Jun 18;161(7):1668-80. doi: 10.1016/j.cell.2015.05.045.
10 Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20.
Mass spectrometry data entry: PXD007570
11 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402