Details of the Probe

General Information of Probe

Probe ID
LDPC0526
Probe Name
C296
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 338.415
Lipid-water partition coefficient (xlogp) 2.85652
Rotatable Bond Count (rotbonds) 10
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C18H22N6O
Canonical SMILES
[H]C#CC([H])([H])C([H])([H])C1(C([H])([H])C([H])([H])N([H])C(=O)c2nc3c(C([H])(C([H])([H])[H])C([H])([H])[H])c([H])nn3c(C([H])([H])[H])c2[H])N=N1
InChI
InChI=1S/C18H22N6O/c1-5-6-7-18(22-23-18)8-9-19-17(25)15-10-13(4)24-16(21-15)14(11-20-24)12(2)3/h1,10-12H,6-9H2,2-4H3,(H,19,25)
InChIKey
CTQSDHBBXYIAKA-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

136 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 11.63  LDD1966 
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 72.50  LDD1966 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 21.41  LDD1966 
Abasic site processing protein HMCES (HMCES) LDTP10322 15.89  LDD1966 
Acid ceramidase (ASAH1) LDTP05905 35.51  LDD1966 
Adenosine deaminase (ADA) LDTP01803 44.94  LDD1966 
ADP-dependent glucokinase (ADPGK) LDTP11127 25.99  LDD1966 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 23.92  LDD1966 
All-trans-retinol 13,14-reductase (RETSAT) LDTP15097 11.47  LDD1966 
Alpha-galactosidase A (GLA) LDTP02141 12.21  LDD1966 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 17.39  LDD1966 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 45.57  LDD1966 
Atlastin-2 (ATL2) LDTP09251 14.12  LDD1966 
ATP-binding cassette sub-family D member 3 (ABCD3) LDTP03424 16.56  LDD1966 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 11.24  LDD1966 
Beta-galactosidase (GLB1) LDTP02837 23.43  LDD1966 
Beta-glucuronidase (GUSB) LDTP02260 15.14  LDD1966 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 23.26  LDD1966 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 19.03  LDD1966 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 25.99  LDD1966 
Calcium-independent phospholipase A2-gamma (PNPLA8) LDTP12318 15.14  LDD1966 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 43.71  LDD1966 
Carboxymethylenebutenolidase homolog (CMBL) LDTP10215 13.83  LDD1966 
Cartilage-associated protein (CRTAP) LDTP01300 26.91  LDD1966 
Catechol O-methyltransferase (COMT) LDTP03145 17.51  LDD1966 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 74.54  LDD1966 
Ceramide synthase 2 (CERS2) LDTP10329 19.16  LDD1966 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 11.88  LDD1966 
Choline kinase alpha (CHKA) LDTP03787 15.03  LDD1966 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 27.67  LDD1966 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 24.93  LDD1966 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 83.87  LDD1966 
Cytochrome b5 type B (CYB5B) LDTP00697 44.02  LDD1966 
Cytochrome c oxidase assembly factor 7 (COA7) LDTP10137 12.38  LDD1966 
DCN1-like protein 4 (DCUN1D4) LDTP09799 99.73  LDD1966 
Dehydrodolichyl diphosphate synthase complex subunit DHDDS (DHDDS) LDTP08177 67.65  LDD1966 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 19.97  LDD1966 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 12.47  LDD1966 
Delta(24)-sterol reductase (DHCR24) LDTP06375 18.77  LDD1966 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 17.63  LDD1966 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 15.45  LDD1966 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 13.00  LDD1966 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 14.62  LDD1966 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 56.89  LDD1966 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 12.73  LDD1966 
E3 SUMO-protein ligase NSE2 (NSMCE2) LDTP10583 16.80  LDD1966 
E3 ubiquitin-protein ligase listerin (LTN1) LDTP01430 12.64  LDD1966 
E3 ubiquitin-protein ligase RNF14 (RNF14) LDTP13154 13.36  LDD1966 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 21.71  LDD1966 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 13.00  LDD1966 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 33.36  LDD1966 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 18.90  LDD1966 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 21.11  LDD1966 
Epoxide hydrolase 1 (EPHX1) LDTP02175 14.62  LDD1966 
Ethanolamine kinase 1 (ETNK1) LDTP12197 29.45  LDD1966 
Eukaryotic translation initiation factor 3 subunit F (EIF3F) LDTP00246 18.38  LDD1966 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 30.91  LDD1966 
Ferrochelatase, mitochondrial (FECH) LDTP03198 15.56  LDD1966 
Glutathione hydrolase 7 (GGT7) LDTP13367 12.91  LDD1966 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 12.64  LDD1966 
Helicase MOV-10 (MOV10) LDTP12233 15.67  LDD1966 
Heme A synthase COX15 (COX15) LDTP07931 14.83  LDD1966 
Heme oxygenase 1 (HMOX1) LDTP02359 30.70  LDD1966 
Heme oxygenase 2 (HMOX2) LDTP03540 43.71  LDD1966 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 24.42  LDD1966 
Holocytochrome c-type synthase (HCCS) LDTP04581 16.91  LDD1966 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 27.47  LDD1966 
Ketosamine-3-kinase (FN3KRP) LDTP16025 12.91  LDD1966 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 17.27  LDD1966 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 32.67  LDD1966 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 14.03  LDD1966 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 15.35  LDD1966 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 20.39  LDD1966 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 28.25  LDD1966 
Lysosomal protective protein (CTSA) LDTP02505 18.64  LDD1966 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 24.93  LDD1966 
Macrophage migration inhibitory factor (MIF) LDTP02713 22.78  LDD1966 
Metalloendopeptidase OMA1, mitochondrial (OMA1) LDTP10249 16.80  LDD1966 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 21.71  LDD1966 
Minor histocompatibility antigen H13 (HM13) LDTP09396 35.02  LDD1966 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 20.11  LDD1966 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 15.78  LDD1966 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 14.22  LDD1966 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 15.56  LDD1966 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 15.56  LDD1966 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 19.16  LDD1966 
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) LDTP01219 12.82  LDD1966 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 41.07  LDD1966 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 16.11  LDD1966 
NADPH--cytochrome P450 reductase (POR) LDTP02848 15.35  LDD1966 
Oligoribonuclease, mitochondrial (REXO2) LDTP13972 38.05  LDD1966 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 51.63  LDD1966 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 16.34  LDD1966 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 13.09  LDD1966 
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) LDTP01562 14.03  LDD1966 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 13.36  LDD1966 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 18.77  LDD1966 
Phosphatidylinositol 4-kinase type 2-alpha (PI4K2A) LDTP11209 11.63  LDD1966 
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (PIP4K2C) LDTP09355 20.68  LDD1966 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 14.83  LDD1966 
Poly(A)-specific ribonuclease PARN (PARN) LDTP01607 12.13  LDD1966 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 15.24  LDD1966 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 21.26  LDD1966 
Probable ATP-dependent RNA helicase DDX28 (DDX28) LDTP12633 16.00  LDD1966 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 13.00  LDD1966 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 17.63  LDD1966 
Prolyl endopeptidase-like (PREPL) LDTP06849 13.64  LDD1966 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 13.00  LDD1966 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 28.44  LDD1966 
Pseudouridylate synthase RPUSD2 (RPUSD2) LDTP15370 14.32  LDD1966 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 14.03  LDD1966 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 11.24  LDD1966 
Ras-related protein Rab-11B (RAB11B) LDTP06501 12.38  LDD1966 
Ras-related protein Rab-24 (RAB24) LDTP10020 13.45  LDD1966 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 26.17  LDD1966 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 11.24  LDD1966 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 46.85  LDD1966 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 13.09  LDD1966 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 14.03  LDD1966 
Serine/threonine-protein kinase OSR1 (OXSR1) LDTP01664 14.32  LDD1966 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 26.91  LDD1966 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 24.08  LDD1966 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 16.34  LDD1966 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 13.45  LDD1966 
Squalene monooxygenase (SQLE) LDTP06142 16.11  LDD1966 
Sulfhydryl oxidase 2 (QSOX2) LDTP07813 17.88  LDD1966 
Trans-3-hydroxy-L-proline dehydratase (L3HYPDH) LDTP10267 13.36  LDD1966 
Translin (TSN) LDTP06427 34.30  LDD1966 
Trimethyllysine dioxygenase, mitochondrial (TMLHE) LDTP12679 13.64  LDD1966 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 11.79  LDD1966 
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCHL3) LDTP02783 13.64  LDD1966 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 22.94  LDD1966 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 17.15  LDD1966 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 11.71  LDD1966 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 44.32  LDD1966 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 14.22  LDD1966 
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⏷ Show the Full List of 136 Enzyme
110 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 12.21  LDD1966 
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 22.47  LDD1966 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 18.13  LDD1966 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 11.39  LDD1966 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 12.21  LDD1966 
Amyloid-beta precursor protein (APP) LDTP02071 26.91  LDD1966 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 11.96  LDD1966 
ATP synthase subunit a (MT-ATP6) LDTP01804 39.40  LDD1966 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 24.25  LDD1966 
BRI3-binding protein (BRI3BP) LDTP15648 47.18  LDD1966 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 14.03  LDD1966 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 24.25  LDD1966 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 19.97  LDD1966 
Derlin-1 (DERL1) LDTP11245 22.32  LDD1966 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 13.18  LDD1966 
Equilibrative nucleoside transporter 1 (SLC29A1) LDTP10985 12.91  LDD1966 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 63.56  LDD1966 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 19.29  LDD1966 
Essential MCU regulator, mitochondrial (SMDT1) LDTP11927 50.91  LDD1966 
Glucose-6-phosphate exchanger SLC37A4 (SLC37A4) LDTP00882 11.71  LDD1966 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 12.55  LDD1966 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 14.52  LDD1966 
Importin-4 (IPO4) LDTP09515 23.43  LDD1966 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 19.84  LDD1966 
Lysosome membrane protein 2 (SCARB2) LDTP06034 21.11  LDD1966 
Major facilitator superfamily domain-containing protein 10 (MFSD10) LDTP06198 15.03  LDD1966 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 28.84  LDD1966 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 15.56  LDD1966 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 25.63  LDD1966 
Metaxin-1 (MTX1) LDTP05900 35.02  LDD1966 
Metaxin-2 (MTX2) LDTP01217 17.27  LDD1966 
Methylosome subunit pICln (CLNS1A) LDTP04597 12.55  LDD1966 
MICOS complex subunit MIC26 (APOO) LDTP11250 21.56  LDD1966 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 25.63  LDD1966 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 17.51  LDD1966 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 16.00  LDD1966 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 22.94  LDD1966 
Mitochondrial glutamate carrier 1 (SLC25A22) LDTP12078 12.64  LDD1966 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 43.41  LDD1966 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 28.64  LDD1966 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 69.55  LDD1966 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 70.03  LDD1966 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 28.64  LDD1966 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 15.56  LDD1966 
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 11.47  LDD1966 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 21.26  LDD1966 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 31.34  LDD1966 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 31.78  LDD1966 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 31.12  LDD1966 
Mpv17-like protein 2 (MPV17L2) LDTP14952 17.88  LDD1966 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 14.22  LDD1966 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 11.31  LDD1966 
Nucleoporin NDC1 (NDC1) LDTP11213 17.15  LDD1966 
Osteopetrosis-associated transmembrane protein 1 (OSTM1) LDTP08327 23.92  LDD1966 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 18.64  LDD1966 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 16.68  LDD1966 
Peroxisomal membrane protein 11A (PEX11A) LDTP01160 17.03  LDD1966 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 14.72  LDD1966 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 20.11  LDD1966 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 12.91  LDD1966 
PRA1 family protein 2 (PRAF2) LDTP01060 14.72  LDD1966 
Prosaposin (PSAP) LDTP02215 18.51  LDD1966 
Protein FAM8A1 (FAM8A1) LDTP16190 21.11  LDD1966 
Protein GPR107 (GPR107) LDTP07236 17.15  LDD1966 
Protein GPR108 (GPR108) LDTP12383 12.13  LDD1966 
Protein spinster homolog 1 (SPNS1) LDTP11844 15.14  LDD1966 
Protein tweety homolog 3 (TTYH3) LDTP11615 31.12  LDD1966 
Protein wntless homolog (WLS) LDTP07156 56.89  LDD1966 
Proton-coupled zinc antiporter SLC30A9, mitochondrial (SLC30A9) LDTP07610 12.30  LDD1966 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 23.75  LDD1966 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 24.08  LDD1966 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 13.64  LDD1966 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 41.36  LDD1966 
Sideroflexin-4 (SFXN4) LDTP07531 12.30  LDD1966 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 18.00  LDD1966 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 64.89  LDD1966 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 40.22  LDD1966 
Sorting nexin-2 (SNX2) LDTP01043 11.39  LDD1966 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 33.59  LDD1966 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 12.55  LDD1966 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 13.27  LDD1966 
Stomatin (STOM) LDTP03380 14.83  LDD1966 
Surfeit locus protein 4 (SURF4) LDTP00592 20.39  LDD1966 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 32.67  LDD1966 
Syntaxin-17 (STX17) LDTP04770 12.47  LDD1966 
Syntaxin-5 (STX5) LDTP05780 15.03  LDD1966 
Syntaxin-6 (STX6) LDTP00857 31.56  LDD1966 
Syntenin-1 (SDCBP) LDTP00310 16.00  LDD1966 
Target of Myb1 membrane trafficking protein (TOM1) LDTP01051 13.55  LDD1966 
Tetraspanin-10 (TSPAN10) LDTP15967 13.36  LDD1966 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 25.81  LDD1966 
Translocation protein SEC62 (SEC62) LDTP15838 11.47  LDD1966 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 52.71  LDD1966 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 19.84  LDD1966 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 47.18  LDD1966 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 24.59  LDD1966 
Transmembrane protein 126A (TMEM126A) LDTP15948 34.30  LDD1966 
Transmembrane protein 160 (TMEM160) LDTP20002 48.84  LDD1966 
Transmembrane protein 199 (TMEM199) LDTP08881 19.43  LDD1966 
Transmembrane protein 205 (TMEM205) LDTP07667 26.91  LDD1966 
Transmembrane protein 214 (TMEM214) LDTP07477 11.88  LDD1966 
Transmembrane protein 245 (TMEM245) LDTP15979 17.03  LDD1966 
Transmembrane protein 87A (TMEM87A) LDTP15481 27.28  LDD1966 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 19.16  LDD1966 
Vacuole membrane protein 1 (VMP1) LDTP10343 17.03  LDD1966 
Vesicle transport through interaction with t-SNAREs homolog 1B (VTI1B) LDTP13201 12.64  LDD1966 
Vezatin (VEZT) LDTP12191 14.32  LDD1966 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 23.75  LDD1966 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 21.11  LDD1966 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 15.78  LDD1966 
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⏷ Show the Full List of 110 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 19.70  LDD1966 
Zinc finger protein 593 (ZNF593) LDTP00295 12.73  LDD1966 
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2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Leukocyte surface antigen CD47 (CD47) LDTP05572 11.96  LDD1966 
Neuroplastin (NPTN) LDTP14205 11.31  LDD1966 
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105 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Alpha-internexin (INA) LDTP06527 14.52  LDD1966 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 14.12  LDD1966 
Apolipoprotein L2 (APOL2) LDTP11076 54.95  LDD1966 
ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) LDTP14716 11.88  LDD1966 
BET1 homolog (BET1) LDTP00555 11.96  LDD1966 
BSD domain-containing protein 1 (BSDC1) LDTP16116 14.32  LDD1966 
Calumenin (CALU) LDTP00887 14.83  LDD1966 
Centrin-2 (CETN2) LDTP03926 13.27  LDD1966 
Centromere protein K (CENPK) LDTP11143 12.21  LDD1966 
Clustered mitochondria protein homolog (CLUH) LDTP14486 13.45  LDD1966 
Coiled-coil domain-containing protein 6 (CCDC6) LDTP06515 14.22  LDD1966 
Cold-inducible RNA-binding protein (CIRBP) LDTP06022 12.73  LDD1966 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 49.18  LDD1966 
DDRGK domain-containing protein 1 (DDRGK1) LDTP10403 11.88  LDD1966 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 17.39  LDD1966 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 13.18  LDD1966 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 11.55  LDD1966 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 28.25  LDD1966 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 33.13  LDD1966 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 20.53  LDD1966 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 16.11  LDD1966 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 13.45  LDD1966 
Ganglioside GM2 activator (GM2A) LDTP02927 22.16  LDD1966 
General transcription factor IIF subunit 1 (GTF2F1) LDTP03729 19.16  LDD1966 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 19.70  LDD1966 
HAUS augmin-like complex subunit 1 (HAUS1) LDTP10184 14.22  LDD1966 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 17.75  LDD1966 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 24.42  LDD1966 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 12.30  LDD1966 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 22.63  LDD1966 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 20.11  LDD1966 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 23.10  LDD1966 
KH domain-containing, RNA-binding, signal transduction-associated protein 3 (KHDRBS3) LDTP01246 11.88  LDD1966 
Kinesin light chain 2 (KLC2) LDTP11695 11.47  LDD1966 
Kinetochore protein Nuf2 (NUF2) LDTP11525 12.55  LDD1966 
Kinetochore-associated protein 1 (KNTC1) LDTP04382 15.89  LDD1966 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 12.91  LDD1966 
Large proline-rich protein BAG6 (BAG6) LDTP04094 11.63  LDD1966 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 24.59  LDD1966 
Lipase maturation factor 2 (LMF2) LDTP15887 19.03  LDD1966 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 15.45  LDD1966 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 15.03  LDD1966 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 15.14  LDD1966 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 19.43  LDD1966 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 46.85  LDD1966 
Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) LDTP00913 14.32  LDD1966 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 13.45  LDD1966 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 64.00  LDD1966 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 32.00  LDD1966 
Mitochondrial import receptor subunit TOM6 homolog (TOMM6) LDTP10113 23.26  LDD1966 
Nucleobindin-1 (NUCB1) LDTP05375 12.04  LDD1966 
Nucleobindin-2 (NUCB2) LDTP05160 42.22  LDD1966 
Nucleolar protein 9 (NOP9) LDTP15283 12.91  LDD1966 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 13.00  LDD1966 
Nurim (NRM) LDTP08606 17.75  LDD1966 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 15.78  LDD1966 
Optic atrophy 3 protein (OPA3) LDTP16006 16.68  LDD1966 
Oxysterol-binding protein-related protein 9 (OSBPL9) LDTP10825 16.45  LDD1966 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 37.79  LDD1966 
Polyadenylate-binding protein-interacting protein 2 (PAIP2) LDTP11044 22.78  LDD1966 
Prefoldin subunit 6 (PFDN6) LDTP00573 12.55  LDD1966 
Programmed cell death protein 5 (PDCD5) LDTP00417 12.13  LDD1966 
Proteasome activator complex subunit 3 (PSME3) LDTP04917 12.47  LDD1966 
Protein CEBPZOS (CEBPZOS) LDTP18883 39.12  LDD1966 
Protein ecdysoneless homolog (ECD) LDTP01711 15.03  LDD1966 
Protein FAM114A2 (FAM114A2) LDTP16080 32.45  LDD1966 
Protein FAM162A (FAM162A) LDTP10056 28.25  LDD1966 
Protein FAM177A1 (FAM177A1) LDTP15398 13.83  LDD1966 
Protein jagunal homolog 1 (JAGN1) LDTP08904 12.91  LDD1966 
Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) LDTP13656 27.86  LDD1966 
Protein LYRIC (MTDH) LDTP08224 15.78  LDD1966 
Protein PBDC1 (PBDC1) LDTP19924 13.00  LDD1966 
Protein unc-119 homolog B (UNC119B) LDTP00105 16.91  LDD1966 
Protein YIF1A (YIF1A) LDTP01494 21.26  LDD1966 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 11.79  LDD1966 
RAD50-interacting protein 1 (RINT1) LDTP07476 14.52  LDD1966 
Ran guanine nucleotide release factor (RANGRF) LDTP12287 13.55  LDD1966 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 11.96  LDD1966 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 13.64  LDD1966 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 11.63  LDD1966 
Reticulocalbin-2 (RCN2) LDTP06097 19.97  LDD1966 
Reticulon-3 (RTN3) LDTP01522 19.84  LDD1966 
Reticulon-4 (RTN4) LDTP12412 27.28  LDD1966 
Retinol-binding protein 1 (RBP1) LDTP02345 23.43  LDD1966 
RNA-binding protein 15 (RBM15) LDTP10832 11.71  LDD1966 
RNA-binding protein FUS (FUS) LDTP03775 12.47  LDD1966 
Seizure 6-like protein 2 (SEZ6L2) LDTP07703 21.71  LDD1966 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 25.81  LDD1966 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 19.43  LDD1966 
Synaptogyrin-2 (SYNGR2) LDTP00859 33.13  LDD1966 
Syntaxin-18 (STX18) LDTP13086 27.47  LDD1966 
T-complex protein 11-like protein 1 (TCP11L1) LDTP12629 12.55  LDD1966 
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) LDTP14263 13.00  LDD1966 
Testis-expressed protein 264 (TEX264) LDTP14259 14.03  LDD1966 
Tetraspanin-6 (TSPAN6) LDTP14458 99.73  LDD1966 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 14.42  LDD1966 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 30.06  LDD1966 
TraB domain-containing protein (TRABD) LDTP19963 25.63  LDD1966 
Transducin beta-like protein 2 (TBL2) LDTP16285 21.71  LDD1966 
Transmembrane protein 209 (TMEM209) LDTP18272 15.89  LDD1966 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 14.62  LDD1966 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 28.44  LDD1966 
Vacuolar protein sorting-associated protein 18 homolog (VPS18) LDTP13019 13.83  LDD1966 
Vimentin (VIM) LDTP02297 21.26  LDD1966 
Zinc finger CCHC domain-containing protein 3 (ZCCHC3) LDTP12623 37.01  LDD1966 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1966 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587