Details of the Target

General Information of Target

Target ID LDTP12629
Target Name T-complex protein 11-like protein 1 (TCP11L1)
Gene Name TCP11L1
Gene ID 55346
Synonyms
T-complex protein 11-like protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAVARLAAVAAWVPCRSWGWAAVPFGPHRGLSVLLARIPQRAPRWLPACRQKTSLSFLNR
PDLPNLAYKKLKGKSPGIIFIPGYLSYMNGTKALAIEEFCKSLGHACIRFDYSGVGSSDG
NSEESTLGKWRKDVLSIIDDLADGPQILVGSSLGGWLMLHAAIARPEKVVALIGVATAAD
TLVTKFNQLPVELKKEVEMKGVWSMPSKYSEEGVYNVQYSFIKEAEHHCLLHSPIPVNCP
IRLLHGMKDDIVPWHTSMQVADRVLSTDVDVILRKHSDHRMREKADIQLLVYTIDDLIDK
LSTIVN
Target Bioclass
Other
Family
TCP11 family
Uniprot ID
Q9NUJ3
Ensemble ID
ENST00000334274.9
HGNC ID
HGNC:25655

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 9 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		13.71  LDD0402  [1]
AHL-Pu-1
 Probe Info  		C115(7.95)  LDD0169  [2]
HHS-465
 Probe Info  		Y307(7.59)  LDD2237  [3]
DBIA
 Probe Info  		C495(1.86)  LDD0080  [4]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [5]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [5]
IPM
 Probe Info  		N.A.  LDD2156  [6]
AOyne
 Probe Info  		11.90  LDD0443  [7]
NAIA_5
 Probe Info  		N.A.  LDD2223  [8]
PAL-AfBPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C064
 Probe Info  		6.45  LDD1761  [9]
C201
 Probe Info  		27.67  LDD1877  [9]
C204
 Probe Info  		8.06  LDD1879  [9]
C296
 Probe Info  		12.55  LDD1966  [9]
C346
 Probe Info  		11.79  LDD2007  [9]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0026  4SU-RNA+native RNA HEK-293T C115(7.95)  LDD0169  [2]
 LDCM0214  AC1 HCT 116 C495(1.32)  LDD0531  [4]
 LDCM0215  AC10 HEK-293T C495(1.24)  LDD0813  [4]
 LDCM0216  AC100 PaTu 8988t C495(0.99)  LDD1095  [4]
 LDCM0217  AC101 PaTu 8988t C495(0.92)  LDD1096  [4]
 LDCM0218  AC102 PaTu 8988t C495(0.89)  LDD1097  [4]
 LDCM0219  AC103 PaTu 8988t C495(1.12)  LDD1098  [4]
 LDCM0220  AC104 PaTu 8988t C495(0.88)  LDD1099  [4]
 LDCM0221  AC105 PaTu 8988t C495(1.04)  LDD1100  [4]
 LDCM0222  AC106 PaTu 8988t C495(0.99)  LDD1101  [4]
 LDCM0223  AC107 PaTu 8988t C495(0.89)  LDD1102  [4]
 LDCM0224  AC108 PaTu 8988t C495(1.13)  LDD1103  [4]
 LDCM0225  AC109 PaTu 8988t C495(0.93)  LDD1104  [4]
 LDCM0226  AC11 HEK-293T C495(1.09)  LDD0824  [4]
 LDCM0227  AC110 PaTu 8988t C495(1.19)  LDD1106  [4]
 LDCM0228  AC111 PaTu 8988t C495(1.11)  LDD1107  [4]
 LDCM0229  AC112 PaTu 8988t C495(1.25)  LDD1108  [4]
 LDCM0230  AC113 HEK-293T C495(0.95)  LDD0828  [4]
 LDCM0231  AC114 HEK-293T C495(0.87)  LDD0829  [4]
 LDCM0232  AC115 HEK-293T C495(0.98)  LDD0830  [4]
 LDCM0233  AC116 HEK-293T C495(0.81)  LDD0831  [4]
 LDCM0234  AC117 HEK-293T C495(0.93)  LDD0832  [4]
 LDCM0235  AC118 HEK-293T C495(1.01)  LDD0833  [4]
 LDCM0236  AC119 HEK-293T C495(0.89)  LDD0834  [4]
 LDCM0237  AC12 HEK-293T C495(1.34)  LDD0835  [4]
 LDCM0238  AC120 HEK-293T C495(0.88)  LDD0836  [4]
 LDCM0239  AC121 HEK-293T C495(0.95)  LDD0837  [4]
 LDCM0240  AC122 HEK-293T C495(0.98)  LDD0838  [4]
 LDCM0241  AC123 HEK-293T C495(0.79)  LDD0839  [4]
 LDCM0242  AC124 HEK-293T C495(0.91)  LDD0840  [4]
 LDCM0243  AC125 HEK-293T C495(1.07)  LDD0841  [4]
 LDCM0244  AC126 HEK-293T C495(1.10)  LDD0842  [4]
 LDCM0245  AC127 HEK-293T C495(0.96)  LDD0843  [4]
 LDCM0246  AC128 HCT 116 C495(1.23)  LDD0563  [4]
 LDCM0247  AC129 HCT 116 C495(0.81)  LDD0564  [4]
 LDCM0249  AC130 HCT 116 C495(0.93)  LDD0566  [4]
 LDCM0250  AC131 HCT 116 C495(0.92)  LDD0567  [4]
 LDCM0251  AC132 HCT 116 C495(0.99)  LDD0568  [4]
 LDCM0252  AC133 HCT 116 C495(0.97)  LDD0569  [4]
 LDCM0253  AC134 HCT 116 C495(1.09)  LDD0570  [4]
 LDCM0254  AC135 HCT 116 C495(0.99)  LDD0571  [4]
 LDCM0255  AC136 HCT 116 C495(1.01)  LDD0572  [4]
 LDCM0256  AC137 HCT 116 C495(0.86)  LDD0573  [4]
 LDCM0257  AC138 HCT 116 C495(0.89)  LDD0574  [4]
 LDCM0258  AC139 HCT 116 C495(0.94)  LDD0575  [4]
 LDCM0259  AC14 HEK-293T C495(0.99)  LDD0857  [4]
 LDCM0260  AC140 HCT 116 C495(1.06)  LDD0577  [4]
 LDCM0261  AC141 HCT 116 C495(1.02)  LDD0578  [4]
 LDCM0262  AC142 HCT 116 C495(0.68)  LDD0579  [4]
 LDCM0263  AC143 HCT 116 C495(1.29)  LDD0580  [4]
 LDCM0264  AC144 HCT 116 C495(1.51)  LDD0581  [4]
 LDCM0265  AC145 HCT 116 C495(1.27)  LDD0582  [4]
 LDCM0266  AC146 HCT 116 C495(1.71)  LDD0583  [4]
 LDCM0267  AC147 HCT 116 C495(1.64)  LDD0584  [4]
 LDCM0268  AC148 HCT 116 C495(2.42)  LDD0585  [4]
 LDCM0269  AC149 HCT 116 C495(1.77)  LDD0586  [4]
 LDCM0270  AC15 HEK-293T C495(1.10)  LDD0868  [4]
 LDCM0271  AC150 HCT 116 C495(1.35)  LDD0588  [4]
 LDCM0272  AC151 HCT 116 C495(1.24)  LDD0589  [4]
 LDCM0273  AC152 HCT 116 C495(1.73)  LDD0590  [4]
 LDCM0274  AC153 HCT 116 C495(2.67)  LDD0591  [4]
 LDCM0621  AC154 HCT 116 C495(1.57)  LDD2158  [4]
 LDCM0622  AC155 HCT 116 C495(1.45)  LDD2159  [4]
 LDCM0623  AC156 HCT 116 C495(1.11)  LDD2160  [4]
 LDCM0624  AC157 HCT 116 C495(1.11)  LDD2161  [4]
 LDCM0276  AC17 HEK-293T C495(1.61)  LDD0874  [4]
 LDCM0277  AC18 HEK-293T C495(1.40)  LDD0875  [4]
 LDCM0278  AC19 HEK-293T C495(1.45)  LDD0876  [4]
 LDCM0279  AC2 HCT 116 C495(1.34)  LDD0596  [4]
 LDCM0280  AC20 HEK-293T C495(1.06)  LDD0878  [4]
 LDCM0281  AC21 HEK-293T C495(0.94)  LDD0879  [4]
 LDCM0282  AC22 HEK-293T C495(1.19)  LDD0880  [4]
 LDCM0283  AC23 HEK-293T C495(1.26)  LDD0881  [4]
 LDCM0284  AC24 HEK-293T C495(1.20)  LDD0882  [4]
 LDCM0285  AC25 HEK-293T C495(0.86)  LDD0883  [4]
 LDCM0286  AC26 HEK-293T C495(0.90)  LDD0884  [4]
 LDCM0287  AC27 HEK-293T C495(0.84)  LDD0885  [4]
 LDCM0288  AC28 HEK-293T C495(1.37)  LDD0886  [4]
 LDCM0289  AC29 HEK-293T C495(0.91)  LDD0887  [4]
 LDCM0290  AC3 HCT 116 C495(1.34)  LDD0607  [4]
 LDCM0291  AC30 HEK-293T C495(0.90)  LDD0889  [4]
 LDCM0292  AC31 HEK-293T C495(0.95)  LDD0890  [4]
 LDCM0293  AC32 HEK-293T C495(0.91)  LDD0891  [4]
 LDCM0294  AC33 HEK-293T C495(0.84)  LDD0892  [4]
 LDCM0295  AC34 HEK-293T C495(0.78)  LDD0893  [4]
 LDCM0296  AC35 HEK-293T C495(1.36)  LDD0894  [4]
 LDCM0297  AC36 HEK-293T C495(1.45)  LDD0895  [4]
 LDCM0298  AC37 HEK-293T C495(1.54)  LDD0896  [4]
 LDCM0299  AC38 HEK-293T C495(1.25)  LDD0897  [4]
 LDCM0300  AC39 HEK-293T C495(1.37)  LDD0898  [4]
 LDCM0301  AC4 HCT 116 C495(1.56)  LDD0618  [4]
 LDCM0302  AC40 HEK-293T C495(1.15)  LDD0900  [4]
 LDCM0303  AC41 HEK-293T C495(1.27)  LDD0901  [4]
 LDCM0304  AC42 HEK-293T C495(1.25)  LDD0902  [4]
 LDCM0305  AC43 HEK-293T C495(1.46)  LDD0903  [4]
 LDCM0306  AC44 HEK-293T C495(1.02)  LDD0904  [4]
 LDCM0307  AC45 HEK-293T C495(1.19)  LDD0905  [4]
 LDCM0308  AC46 HEK-293T C495(1.13)  LDD0906  [4]
 LDCM0309  AC47 HEK-293T C495(1.23)  LDD0907  [4]
 LDCM0310  AC48 HEK-293T C495(1.09)  LDD0908  [4]
 LDCM0311  AC49 HEK-293T C495(1.16)  LDD0909  [4]
 LDCM0312  AC5 HCT 116 C495(1.61)  LDD0629  [4]
 LDCM0313  AC50 HEK-293T C495(1.26)  LDD0911  [4]
 LDCM0314  AC51 HEK-293T C495(1.19)  LDD0912  [4]
 LDCM0315  AC52 HEK-293T C495(1.12)  LDD0913  [4]
 LDCM0316  AC53 HEK-293T C495(1.17)  LDD0914  [4]
 LDCM0317  AC54 HEK-293T C495(1.11)  LDD0915  [4]
 LDCM0318  AC55 HEK-293T C495(1.15)  LDD0916  [4]
 LDCM0319  AC56 HEK-293T C495(1.15)  LDD0917  [4]
 LDCM0320  AC57 HEK-293T C495(1.05)  LDD0918  [4]
 LDCM0321  AC58 HEK-293T C495(1.06)  LDD0919  [4]
 LDCM0322  AC59 HEK-293T C495(1.09)  LDD0920  [4]
 LDCM0323  AC6 HEK-293T C495(1.01)  LDD0921  [4]
 LDCM0324  AC60 HEK-293T C495(2.61)  LDD0922  [4]
 LDCM0325  AC61 HEK-293T C495(1.21)  LDD0923  [4]
 LDCM0326  AC62 HEK-293T C495(1.09)  LDD0924  [4]
 LDCM0327  AC63 HEK-293T C495(1.00)  LDD0925  [4]
 LDCM0328  AC64 HEK-293T C495(1.03)  LDD0926  [4]
 LDCM0329  AC65 HEK-293T C495(0.97)  LDD0927  [4]
 LDCM0330  AC66 HEK-293T C495(0.98)  LDD0928  [4]
 LDCM0331  AC67 HEK-293T C495(0.96)  LDD0929  [4]
 LDCM0332  AC68 HEK-293T C495(0.80)  LDD0930  [4]
 LDCM0333  AC69 HEK-293T C495(1.09)  LDD0931  [4]
 LDCM0334  AC7 HEK-293T C495(1.14)  LDD0932  [4]
 LDCM0335  AC70 HEK-293T C495(0.89)  LDD0933  [4]
 LDCM0336  AC71 HEK-293T C495(1.05)  LDD0934  [4]
 LDCM0337  AC72 HEK-293T C495(1.17)  LDD0935  [4]
 LDCM0338  AC73 HEK-293T C495(0.81)  LDD0936  [4]
 LDCM0339  AC74 HEK-293T C495(1.01)  LDD0937  [4]
 LDCM0340  AC75 HEK-293T C495(1.24)  LDD0938  [4]
 LDCM0341  AC76 HEK-293T C495(0.93)  LDD0939  [4]
 LDCM0342  AC77 HEK-293T C495(0.83)  LDD0940  [4]
 LDCM0343  AC78 HEK-293T C495(0.96)  LDD0941  [4]
 LDCM0344  AC79 HEK-293T C495(1.29)  LDD0942  [4]
 LDCM0345  AC8 HEK-293T C495(1.13)  LDD0943  [4]
 LDCM0346  AC80 HEK-293T C495(1.13)  LDD0944  [4]
 LDCM0347  AC81 HEK-293T C495(0.91)  LDD0945  [4]
 LDCM0348  AC82 HEK-293T C495(0.77)  LDD0946  [4]
 LDCM0349  AC83 HEK-293T C495(1.00)  LDD0947  [4]
 LDCM0350  AC84 HEK-293T C495(0.62)  LDD0948  [4]
 LDCM0351  AC85 HEK-293T C495(0.65)  LDD0949  [4]
 LDCM0352  AC86 HEK-293T C495(0.71)  LDD0950  [4]
 LDCM0353  AC87 HEK-293T C495(0.69)  LDD0951  [4]
 LDCM0354  AC88 HEK-293T C495(1.02)  LDD0952  [4]
 LDCM0355  AC89 HEK-293T C495(0.91)  LDD0953  [4]
 LDCM0357  AC90 HEK-293T C495(0.46)  LDD0955  [4]
 LDCM0358  AC91 HEK-293T C495(0.54)  LDD0956  [4]
 LDCM0359  AC92 HEK-293T C495(0.84)  LDD0957  [4]
 LDCM0360  AC93 HEK-293T C495(0.73)  LDD0958  [4]
 LDCM0361  AC94 HEK-293T C495(0.92)  LDD0959  [4]
 LDCM0362  AC95 HEK-293T C495(1.16)  LDD0960  [4]
 LDCM0363  AC96 HEK-293T C495(1.49)  LDD0961  [4]
 LDCM0364  AC97 HEK-293T C495(0.12)  LDD0962  [4]
 LDCM0365  AC98 PaTu 8988t C495(0.95)  LDD1244  [4]
 LDCM0366  AC99 PaTu 8988t C495(0.82)  LDD1245  [4]
 LDCM0248  AKOS034007472 HEK-293T C495(1.21)  LDD0846  [4]
 LDCM0356  AKOS034007680 HEK-293T C495(0.95)  LDD0954  [4]
 LDCM0275  AKOS034007705 HEK-293T C495(0.89)  LDD0873  [4]
 LDCM0632  CL-Sc Hep-G2 C495(1.38)  LDD2227  [8]
 LDCM0367  CL1 HCT 116 C495(0.87)  LDD0684  [4]
 LDCM0368  CL10 HCT 116 C495(10.53)  LDD0685  [4]
 LDCM0369  CL100 HCT 116 C495(1.77)  LDD0686  [4]
 LDCM0370  CL101 HEK-293T C495(0.74)  LDD0968  [4]
 LDCM0371  CL102 HEK-293T C495(0.94)  LDD0969  [4]
 LDCM0372  CL103 HEK-293T C495(1.22)  LDD0970  [4]
 LDCM0373  CL104 HEK-293T C495(1.17)  LDD0971  [4]
 LDCM0374  CL105 HEK-293T C495(1.07)  LDD0972  [4]
 LDCM0375  CL106 HEK-293T C495(1.07)  LDD0973  [4]
 LDCM0376  CL107 HEK-293T C495(1.28)  LDD0974  [4]
 LDCM0377  CL108 HEK-293T C495(1.61)  LDD0975  [4]
 LDCM0378  CL109 HEK-293T C495(1.18)  LDD0976  [4]
 LDCM0379  CL11 HCT 116 C495(1.25)  LDD0696  [4]
 LDCM0380  CL110 HEK-293T C495(1.02)  LDD0978  [4]
 LDCM0381  CL111 HEK-293T C495(1.20)  LDD0979  [4]
 LDCM0382  CL112 HEK-293T C495(0.81)  LDD0980  [4]
 LDCM0383  CL113 HEK-293T C495(0.99)  LDD0981  [4]
 LDCM0384  CL114 HEK-293T C495(0.68)  LDD0982  [4]
 LDCM0385  CL115 HEK-293T C495(0.99)  LDD0983  [4]
 LDCM0386  CL116 HEK-293T C495(0.71)  LDD0984  [4]
 LDCM0387  CL117 HEK-293T C495(1.35)  LDD0985  [4]
 LDCM0388  CL118 HEK-293T C495(1.33)  LDD0986  [4]
 LDCM0389  CL119 HEK-293T C495(1.03)  LDD0987  [4]
 LDCM0390  CL12 HCT 116 C495(1.43)  LDD0707  [4]
 LDCM0391  CL120 HEK-293T C495(1.10)  LDD0989  [4]
 LDCM0392  CL121 HEK-293T C495(0.92)  LDD0990  [4]
 LDCM0393  CL122 HEK-293T C495(0.95)  LDD0991  [4]
 LDCM0394  CL123 HEK-293T C495(2.19)  LDD0992  [4]
 LDCM0395  CL124 HEK-293T C495(1.35)  LDD0993  [4]
 LDCM0396  CL125 HEK-293T C495(0.99)  LDD0994  [4]
 LDCM0397  CL126 HEK-293T C495(1.07)  LDD0995  [4]
 LDCM0398  CL127 HEK-293T C495(1.15)  LDD0996  [4]
 LDCM0399  CL128 HEK-293T C495(1.08)  LDD0997  [4]
 LDCM0400  CL13 HCT 116 C495(1.09)  LDD0717  [4]
 LDCM0401  CL14 HCT 116 C495(1.01)  LDD0718  [4]
 LDCM0402  CL15 HCT 116 C495(1.07)  LDD0719  [4]
 LDCM0403  CL16 HEK-293T C495(0.82)  LDD1001  [4]
 LDCM0404  CL17 HEK-293T C495(1.01)  LDD1002  [4]
 LDCM0405  CL18 HEK-293T C495(1.13)  LDD1003  [4]
 LDCM0406  CL19 HEK-293T C495(0.93)  LDD1004  [4]
 LDCM0407  CL2 HCT 116 C495(0.92)  LDD0724  [4]
 LDCM0408  CL20 HEK-293T C495(1.31)  LDD1006  [4]
 LDCM0409  CL21 HEK-293T C495(1.13)  LDD1007  [4]
 LDCM0410  CL22 HEK-293T C495(1.01)  LDD1008  [4]
 LDCM0411  CL23 HEK-293T C495(1.14)  LDD1009  [4]
 LDCM0412  CL24 HEK-293T C495(1.22)  LDD1010  [4]
 LDCM0413  CL25 HEK-293T C495(1.18)  LDD1011  [4]
 LDCM0414  CL26 HEK-293T C495(1.39)  LDD1012  [4]
 LDCM0415  CL27 HEK-293T C495(0.95)  LDD1013  [4]
 LDCM0416  CL28 HEK-293T C495(1.08)  LDD1014  [4]
 LDCM0417  CL29 HEK-293T C495(0.83)  LDD1015  [4]
 LDCM0418  CL3 HCT 116 C495(0.85)  LDD0735  [4]
 LDCM0419  CL30 HEK-293T C495(0.72)  LDD1017  [4]
 LDCM0420  CL31 HCT 116 C495(0.89)  LDD0737  [4]
 LDCM0421  CL32 HCT 116 C495(0.90)  LDD0738  [4]
 LDCM0422  CL33 HCT 116 C495(0.98)  LDD0739  [4]
 LDCM0423  CL34 HCT 116 C495(0.98)  LDD0740  [4]
 LDCM0424  CL35 HCT 116 C495(1.04)  LDD0741  [4]
 LDCM0425  CL36 HCT 116 C495(1.12)  LDD0742  [4]
 LDCM0426  CL37 HCT 116 C495(1.11)  LDD0743  [4]
 LDCM0428  CL39 HCT 116 C495(0.89)  LDD0745  [4]
 LDCM0429  CL4 HCT 116 C495(0.85)  LDD0746  [4]
 LDCM0430  CL40 HCT 116 C495(5.36)  LDD0747  [4]
 LDCM0431  CL41 HCT 116 C495(0.92)  LDD0748  [4]
 LDCM0432  CL42 HCT 116 C495(1.07)  LDD0749  [4]
 LDCM0433  CL43 HCT 116 C495(0.89)  LDD0750  [4]
 LDCM0434  CL44 HCT 116 C495(0.92)  LDD0751  [4]
 LDCM0435  CL45 HCT 116 C495(1.04)  LDD0752  [4]
 LDCM0436  CL46 HCT 116 C495(0.92)  LDD0753  [4]
 LDCM0437  CL47 HCT 116 C495(1.18)  LDD0754  [4]
 LDCM0438  CL48 HCT 116 C495(0.88)  LDD0755  [4]
 LDCM0439  CL49 HCT 116 C495(1.07)  LDD0756  [4]
 LDCM0440  CL5 HCT 116 C495(0.99)  LDD0757  [4]
 LDCM0441  CL50 HCT 116 C495(1.15)  LDD0758  [4]
 LDCM0442  CL51 HCT 116 C495(1.14)  LDD0759  [4]
 LDCM0443  CL52 HCT 116 C495(1.08)  LDD0760  [4]
 LDCM0444  CL53 HCT 116 C495(0.93)  LDD0761  [4]
 LDCM0445  CL54 HCT 116 C495(0.87)  LDD0762  [4]
 LDCM0446  CL55 HCT 116 C495(0.81)  LDD0763  [4]
 LDCM0447  CL56 HCT 116 C495(0.94)  LDD0764  [4]
 LDCM0448  CL57 HCT 116 C495(1.06)  LDD0765  [4]
 LDCM0449  CL58 HCT 116 C495(0.80)  LDD0766  [4]
 LDCM0450  CL59 HCT 116 C495(1.13)  LDD0767  [4]
 LDCM0451  CL6 HCT 116 C495(1.12)  LDD0768  [4]
 LDCM0452  CL60 HCT 116 C495(1.02)  LDD0769  [4]
 LDCM0453  CL61 HCT 116 C495(1.20)  LDD0770  [4]
 LDCM0454  CL62 HCT 116 C495(1.20)  LDD0771  [4]
 LDCM0455  CL63 HCT 116 C495(1.17)  LDD0772  [4]
 LDCM0456  CL64 HCT 116 C495(1.39)  LDD0773  [4]
 LDCM0457  CL65 HCT 116 C495(1.15)  LDD0774  [4]
 LDCM0458  CL66 HCT 116 C495(1.41)  LDD0775  [4]
 LDCM0459  CL67 HCT 116 C495(1.29)  LDD0776  [4]
 LDCM0460  CL68 HCT 116 C495(1.30)  LDD0777  [4]
 LDCM0461  CL69 HCT 116 C495(1.14)  LDD0778  [4]
 LDCM0462  CL7 HCT 116 C495(1.35)  LDD0779  [4]
 LDCM0463  CL70 HCT 116 C495(1.15)  LDD0780  [4]
 LDCM0464  CL71 HCT 116 C495(1.41)  LDD0781  [4]
 LDCM0465  CL72 HCT 116 C495(1.17)  LDD0782  [4]
 LDCM0466  CL73 HCT 116 C495(1.41)  LDD0783  [4]
 LDCM0467  CL74 HCT 116 C495(1.32)  LDD0784  [4]
 LDCM0469  CL76 HEK-293T C495(1.52)  LDD1067  [4]
 LDCM0470  CL77 HEK-293T C495(1.91)  LDD1068  [4]
 LDCM0471  CL78 HEK-293T C495(1.30)  LDD1069  [4]
 LDCM0472  CL79 HEK-293T C495(1.36)  LDD1070  [4]
 LDCM0473  CL8 HCT 116 C495(3.71)  LDD0790  [4]
 LDCM0474  CL80 HEK-293T C495(1.39)  LDD1072  [4]
 LDCM0475  CL81 HEK-293T C495(1.19)  LDD1073  [4]
 LDCM0476  CL82 HEK-293T C495(1.96)  LDD1074  [4]
 LDCM0477  CL83 HEK-293T C495(2.27)  LDD1075  [4]
 LDCM0478  CL84 HEK-293T C495(1.45)  LDD1076  [4]
 LDCM0479  CL85 HEK-293T C495(1.69)  LDD1077  [4]
 LDCM0480  CL86 HEK-293T C495(1.43)  LDD1078  [4]
 LDCM0481  CL87 HEK-293T C495(1.56)  LDD1079  [4]
 LDCM0482  CL88 HEK-293T C495(1.85)  LDD1080  [4]
 LDCM0483  CL89 HEK-293T C495(1.91)  LDD1081  [4]
 LDCM0484  CL9 HCT 116 C495(1.12)  LDD0801  [4]
 LDCM0485  CL90 HEK-293T C495(1.60)  LDD1083  [4]
 LDCM0486  CL91 HCT 116 C495(1.21)  LDD0803  [4]
 LDCM0487  CL92 HCT 116 C495(1.27)  LDD0804  [4]
 LDCM0488  CL93 HCT 116 C495(1.09)  LDD0805  [4]
 LDCM0489  CL94 HCT 116 C495(1.46)  LDD0806  [4]
 LDCM0490  CL95 HCT 116 C495(1.53)  LDD0807  [4]
 LDCM0491  CL96 HCT 116 C495(1.20)  LDD0808  [4]
 LDCM0492  CL97 HCT 116 C495(1.78)  LDD0809  [4]
 LDCM0493  CL98 HCT 116 C495(1.47)  LDD0810  [4]
 LDCM0494  CL99 HCT 116 C495(1.37)  LDD0811  [4]
 LDCM0495  E2913 HEK-293T C115(1.21); C495(1.05)  LDD1698  [10]
 LDCM0573  Fragment11 Ramos C495(1.04)  LDD2190  [11]
 LDCM0574  Fragment12 Ramos C495(1.31)  LDD2191  [11]
 LDCM0576  Fragment14 Ramos C495(2.12)  LDD2193  [11]
 LDCM0580  Fragment21 Ramos C495(1.21)  LDD2195  [11]
 LDCM0582  Fragment23 Ramos C495(0.63)  LDD2196  [11]
 LDCM0578  Fragment27 Ramos C495(0.67)  LDD2197  [11]
 LDCM0586  Fragment28 Ramos C495(0.81)  LDD2198  [11]
 LDCM0589  Fragment31 Ramos C495(0.61)  LDD2200  [11]
 LDCM0590  Fragment32 Ramos C495(0.66)  LDD2201  [11]
 LDCM0468  Fragment33 HCT 116 C495(1.11)  LDD0785  [4]
 LDCM0596  Fragment38 Ramos C495(0.45)  LDD2203  [11]
 LDCM0566  Fragment4 Ramos C495(1.18)  LDD2184  [11]
 LDCM0427  Fragment51 HCT 116 C495(3.40)  LDD0744  [4]
 LDCM0614  Fragment56 Ramos C495(0.98)  LDD2205  [11]
 LDCM0022  KB02 HCT 116 C495(1.86)  LDD0080  [4]
 LDCM0023  KB03 HCT 116 C495(1.12)  LDD0081  [4]
 LDCM0024  KB05 HCT 116 C495(1.34)  LDD0082  [4]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
CCR4-NOT transcription complex subunit 7 (CNOT7) CAF1 family Q9UIV1
Prostamide/prostaglandin F synthase (PRXL2B) Peroxiredoxin-like PRXL2 family Q8TBF2
26S proteasome non-ATPase regulatory subunit 4 (PSMD4) Proteasome subunit S5A family P55036
DNA excision repair protein ERCC-6-like 2 (ERCC6L2) SNF2/RAD54 helicase family Q5T890
E3 ubiquitin-protein ligase TRIM21 (TRIM21) TRIM/RBCC family P19474
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Importin-4 (IPO4) Importin beta family Q8TEX9
Transcription factor
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Paired box protein Pax-6 (PAX6) Paired homeobox family P26367
High mobility group protein 20A (HMG20A) . Q9NP66
Homeobox protein MOX-1 (MEOX1) . P50221
LIM/homeobox protein Lhx2 (LHX2) . P50458
T-box transcription factor TBX6 (TBX6) . O95947
Other
Click To Hide/Show 7 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
DNA damage-inducible transcript 4-like protein (DDIT4L) DDIT4 family Q96D03
SNW domain-containing protein 1 (SNW1) SNW family Q13573
Translin-associated protein X (TSNAX) Translin family Q99598
Vacuolar protein sorting-associated protein 52 homolog (VPS52) VPS52 family Q8N1B4
Melanoma-associated antigen 12 (MAGEA12) . P43365
Syntenin-2 (SDCBP2) . Q9H190
WW domain-containing transcription regulator protein 1 (WWTR1) . Q9GZV5

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
3 Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. Nat Chem Biol. 2020 Feb;16(2):150-159. doi: 10.1038/s41589-019-0404-5. Epub 2019 Nov 25.
4 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
5 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
6 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
7 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
8 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
9 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
10 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
11 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578