Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C201  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 178 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP08933  Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (CSGALNACT2) 99.7
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 99.7
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 99.7
 LDTP00697  Cytochrome b5 type B (CYB5B) 99.7
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 99.7
 LDTP02359  Heme oxygenase 1 (HMOX1) 99.7
 LDTP03540  Heme oxygenase 2 (HMOX2) 99.7
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 99.7
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 99.7
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 99.7
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 99.7
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 99.7
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 99.7
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 99.7
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 99.7
 LDTP05905  Acid ceramidase (ASAH1) 94.4
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 90.5
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 89.9
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 86.8
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 86.8
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 86.2
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 86.2
 LDTP03779  Copper-transporting ATPase 2 (ATP7B) 81.0
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 79.3
 LDTP06617  Ceramide glucosyltransferase (UGCG) 77.7
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 66.3
 LDTP06067  Tubulin--tyrosine ligase-like protein 12 (TTLL12) 63.6
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) 60.5
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 57.7
 LDTP01065  E3 ubiquitin-protein ligase TRIM13 (TRIM13) 57.3
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 55.7
 LDTP09666  Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) 54.9
 LDTP12757  E3 ubiquitin-protein ligase MARCHF5 (MARCHF5) 52.3
 LDTP15328  Dolichyldiphosphatase 1 (DOLPP1) 52.0
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 50.2
 LDTP12253  Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) 50.2
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 49.9
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 48.5
 LDTP14030  V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) 48.5
 LDTP05758  S-methyl-5'-thioadenosine phosphorylase (MTAP) 48.2
 LDTP06977  GPI ethanolamine phosphate transferase 2 (PIGG) 47.8
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 47.5
 LDTP05476  3-ketodihydrosphingosine reductase (KDSR) 46.9
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 46.5
 LDTP03145  Catechol O-methyltransferase (COMT) 46.2
 LDTP04334  DNA ligase 3 (LIG3) 45.3
 LDTP02539  Lysosomal acid phosphatase (ACP2) 44.9
 LDTP03854  Vitamin K-dependent gamma-carboxylase (GGCX) 44.6
 LDTP11127  ADP-dependent glucokinase (ADPGK) 44.3
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 44.3
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 44.0
 LDTP03787  Choline kinase alpha (CHKA) 44.0
 LDTP12763  Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) 44.0
 LDTP07931  Heme A synthase COX15 (COX15) 43.7
 LDTP04634  Alpha-N-acetylglucosaminidase (NAGLU) 43.4
 LDTP10329  Ceramide synthase 2 (CERS2) 42.8
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 42.8
 LDTP13352  GTP:AMP phosphotransferase AK3, mitochondrial (AK3) 42.5
 LDTP13486  Long-chain-fatty-acid--CoA ligase 6 (ACSL6) 42.2
 LDTP02505  Lysosomal protective protein (CTSA) 42.2
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) 41.1
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 39.9
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 39.7
 LDTP10699  E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) 39.7
 LDTP03198  Ferrochelatase, mitochondrial (FECH) 39.7
 LDTP00701  D-3-phosphoglycerate dehydrogenase (PHGDH) 39.1
 LDTP14427  Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L) 38.9
 LDTP08790  Mitochondrial cardiolipin hydrolase (PLD6) 38.3
 LDTP02896  Sphingomyelin phosphodiesterase (SMPD1) 38.3
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 38.1
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 38.1
 LDTP09874  Endoplasmic reticulum protein SC65 (P3H4) 37.8
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 37.5
 LDTP13367  Glutathione hydrolase 7 (GGT7) 37.3
 LDTP11273  N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) 36.8
 LDTP10471  Protein disulfide-isomerase TMX3 (TMX3) 36.0
 LDTP10020  Ras-related protein Rab-24 (RAB24) 36.0
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 36.0
 LDTP09251  Atlastin-2 (ATL2) 35.8
 LDTP04246  Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) 35.0
 LDTP06142  Squalene monooxygenase (SQLE) 34.8
 LDTP06657  2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) 34.5
 LDTP09395  Signal peptide peptidase-like 2A (SPPL2A) 34.5
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) 34.3
 LDTP10038  Mitochondrial ubiquitin ligase activator of NFKB 1 (MUL1) 34.3
 LDTP13986  Vesicle transport protein GOT1B (GOLT1B) 34.3
 LDTP10550  Dehydrogenase/reductase SDR family member 1 (DHRS1) 34.1
 LDTP06325  3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) 33.8
 LDTP07966  COP9 signalosome complex subunit 6 (COPS6) 33.8
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 33.4
 LDTP08596  Mitochondrial Rho GTPase 2 (RHOT2) 33.1
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 32.9
 LDTP10182  TLC domain-containing protein 1 (TLCD1) 32.9
 LDTP08530  Mitofusin-1 (MFN1) 32.7
 LDTP04542  Thimet oligopeptidase (THOP1) 32.7
 LDTP03418  Proteasome subunit beta type-6 (PSMB6) 32.2
 LDTP03842  Squalene synthase (FDFT1) 32.2
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 32.0
 LDTP07227  Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) 32.0
 LDTP02000  3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) 31.8
 LDTP06905  Acylglycerol kinase, mitochondrial (AGK) 31.8
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 31.8
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 31.8
 LDTP15484  Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) 31.8
 LDTP11187  COP9 signalosome complex subunit 4 (COPS4) 31.6
 LDTP00589  Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) 31.6
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 31.3
 LDTP15988  Probable serine carboxypeptidase CPVL (CPVL) 31.1
 LDTP09188  Lysophosphatidylcholine acyltransferase 1 (LPCAT1) 30.9
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 30.9
 LDTP14311  SEC23-interacting protein (SEC23IP) 30.9
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 30.7
 LDTP00836  ATPase GET3 (GET3) 30.7
 LDTP07503  Endoplasmic reticulum aminopeptidase 2 (ERAP2) 30.7
 LDTP04531  Hexokinase-2 (HK2) 30.7
 LDTP12105  L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) 30.7
 LDTP10930  Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) 30.5
 LDTP07831  Transmembrane protein with metallophosphoesterase domain (TMPPE) 30.5
 LDTP06986  Rab-like protein 3 (RABL3) 30.1
 LDTP10981  Mitochondrial intermediate peptidase (MIPEP) 29.9
 LDTP00597  Serine palmitoyltransferase 1 (SPTLC1) 29.9
 LDTP09845  Geranylgeranyl transferase type-2 subunit alpha (RABGGTA) 29.7
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 29.7
 LDTP00877  Protein SCO2 homolog, mitochondrial (SCO2) 29.7
 LDTP03189  Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) 29.4
 LDTP16070  Epimerase family protein SDR39U1 (SDR39U1) 29.4
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 29.4
 LDTP12867  Very-long-chain enoyl-CoA reductase (TECR) 29.4
 LDTP06645  Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) 29.2
 LDTP01649  Phosphatidate cytidylyltransferase 2 (CDS2) 29.2
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 29.2
 LDTP02837  Beta-galactosidase (GLB1) 29.0
 LDTP05228  Calcium-transporting ATPase type 2C member 1 (ATP2C1) 29.0
 LDTP11199  DCN1-like protein 5 (DCUN1D5) 29.0
 LDTP13358  Leucyl-cystinyl aminopeptidase (LNPEP) 29.0
 LDTP02141  Alpha-galactosidase A (GLA) 28.6
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2) 28.6
 LDTP01759  Histone-lysine N-methyltransferase NSD2 (NSD2) 28.4
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 28.4
 LDTP00325  Pirin (PIR) 28.2
 LDTP11284  Phosphatidylserine synthase 2 (PTDSS2) 27.9
 LDTP05422  Copper-transporting ATPase 1 (ATP7A) 27.7
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 27.5
 LDTP04164  NADP-dependent malic enzyme (ME1) 27.5
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 27.5
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 27.5
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 27.1
 LDTP01514  NADH dehydrogenase 1 beta subcomplex subunit 4 (NDUFB4) 26.9
 LDTP13720  Ubiquitin carboxyl-terminal hydrolase 24 (USP24) 26.9
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 26.9
 LDTP09095  Diacylglycerol lipase-beta (DAGLB) 26.7
 LDTP06432  Pachytene checkpoint protein 2 homolog (TRIP13) 26.5
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 26.4
 LDTP10267  Trans-3-hydroxy-L-proline dehydratase (L3HYPDH) 26.4
 LDTP10966  Microsomal glutathione S-transferase 2 (MGST2) 26.2
 LDTP12720  Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) 26.2
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 26.0
 LDTP00186  Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) 25.8
 LDTP12303  ATP-binding cassette sub-family B member 6 (ABCB6) 25.8
 LDTP04581  Holocytochrome c-type synthase (HCCS) 25.8
 LDTP02486  Lysosomal alpha-glucosidase (GAA) 25.8
 LDTP01335  Protein SCO1 homolog, mitochondrial (SCO1) 25.8
 LDTP12679  Trimethyllysine dioxygenase, mitochondrial (TMLHE) 25.8
 LDTP00717  Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPSS1) 25.6
 LDTP15155  Thiol S-methyltransferase TMT1B (TMT1B) 25.5
 LDTP01368  Triple functional domain protein (TRIO) 25.3
 LDTP02150  ATP synthase subunit beta, mitochondrial (ATP5F1B) 25.1
 LDTP00950  Dynamin-like 120 kDa protein, mitochondrial (OPA1) 25.1
 LDTP02362  Dihydrolipoyl dehydrogenase, mitochondrial (DLD) 24.4
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 24.4
 LDTP02169  Beta-hexosaminidase subunit alpha (HEXA) 24.3
 LDTP07672  E3 ubiquitin-protein ligase LRSAM1 (LRSAM1) 24.1
 LDTP09814  Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) 23.9
 LDTP01502  NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) 23.9
 LDTP09835  GPI-anchor transamidase (PIGK) 23.8
 LDTP05409  Antigen peptide transporter 2 (TAP2) 23.6
 LDTP13959  Dehydrogenase/reductase SDR family member 7 (DHRS7) 23.6
 LDTP08859  Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) 23.6
Transporter and channel
Click to Show/Hide to Show 128 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 99.7
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 99.7
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 99.7
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 99.7
 LDTP10669  Melanoma inhibitory activity protein 2 (MIA2) 99.7
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 99.7
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 99.7
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 99.7
 LDTP02215  Prosaposin (PSAP) 99.7
 LDTP11615  Protein tweety homolog 3 (TTYH3) 99.7
 LDTP00547  Secretory carrier-associated membrane protein 2 (SCAMP2) 99.7
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 99.7
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 99.7
 LDTP16813  Tetraspanin-3 (TSPAN3) 99.7
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 99.7
 LDTP15948  Transmembrane protein 126A (TMEM126A) 99.7
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 99.7
 LDTP05900  Metaxin-1 (MTX1) 98.4
 LDTP07236  Protein GPR107 (GPR107) 95.0
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 94.4
 LDTP01542  Golgi SNAP receptor complex member 1 (GOSR1) 88.6
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 83.3
 LDTP00541  NPC intracellular cholesterol transporter 1 (NPC1) 81.0
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 80.4
 LDTP08981  Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) 73.5
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 72.5
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 70.5
 LDTP13953  Endophilin-B1 (SH3GLB1) 70.5
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 70.5
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 70.0
 LDTP03559  High affinity cationic amino acid transporter 1 (SLC7A1) 68.1
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 66.3
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 63.6
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 62.2
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 58.1
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 57.7
 LDTP08881  Transmembrane protein 199 (TMEM199) 53.4
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 52.7
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 51.6
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 49.5
 LDTP11250  MICOS complex subunit MIC26 (APOO) 49.2
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 48.8
 LDTP02655  Lysosome-associated membrane glycoprotein 2 (LAMP2) 48.2
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 48.2
 LDTP14636  Solute carrier family 25 member 16 (SLC25A16) 48.2
 LDTP00262  Acetyl-coenzyme A transporter 1 (SLC33A1) 44.9
 LDTP06365  Transmembrane emp24 domain-containing protein 2 (TMED2) 44.9
 LDTP09028  Mitoguardin 1 (MIGA1) 43.4
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 41.6
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 41.1
 LDTP13164  Protein sel-1 homolog 1 (SEL1L) 41.1
 LDTP11634  Derlin-2 (DERL2) 40.2
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 39.9
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 37.8
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 37.0
 LDTP12451  Integral membrane protein 2C (ITM2C) 36.8
 LDTP03380  Stomatin (STOM) 36.8
 LDTP04463  H(+)/Cl(-) exchange transporter 7 (CLCN7) 36.5
 LDTP07439  Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) 36.3
 LDTP07058  Transmembrane protein 201 (TMEM201) 36.3
 LDTP01380  Wolframin (WFS1) 36.0
 LDTP02562  Lysosome-associated membrane glycoprotein 1 (LAMP1) 35.5
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 35.3
 LDTP11095  Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) 35.3
 LDTP09515  Importin-4 (IPO4) 35.0
 LDTP10065  Transmembrane protein 230 (TMEM230) 35.0
 LDTP06293  Metal cation symporter ZIP14 (SLC39A14) 34.8
 LDTP09788  Sorting nexin-19 (SNX19) 33.6
 LDTP04459  H(+)/Cl(-) exchange transporter 3 (CLCN3) 33.4
 LDTP01060  PRA1 family protein 2 (PRAF2) 32.9
 LDTP13393  Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) 32.4
 LDTP04426  B-cell receptor-associated protein 31 (BCAP31) 32.2
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 31.8
 LDTP10804  Chloride channel CLIC-like protein 1 (CLCC1) 31.6
 LDTP01200  Peroxisomal membrane protein PEX14 (PEX14) 31.3
 LDTP14200  Mitochondrial ornithine transporter 1 (SLC25A15) 31.1
 LDTP04787  Transmembrane protein 33 (TMEM33) 30.5
 LDTP10073  Protein RFT1 homolog (RFT1) 30.3
 LDTP12704  Anoctamin-10 (ANO10) 29.9
 LDTP10769  Intermembrane lipid transfer protein VPS13A (VPS13A) 29.2
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 29.0
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 29.0
 LDTP15733  Solute carrier family 25 member 44 (SLC25A44) 29.0
 LDTP06660  MICOS complex subunit MIC60 (IMMT) 28.6
 LDTP14084  Sorting and assembly machinery component 50 homolog (SAMM50) 28.6
 LDTP02071  Amyloid-beta precursor protein (APP) 28.4
 LDTP18153  Major facilitator superfamily domain-containing protein 3 (MFSD3) 28.4
 LDTP03869  Protein Mpv17 (MPV17) 28.4
 LDTP12979  Transmembrane protein 14C (TMEM14C) 28.4
 LDTP11213  Nucleoporin NDC1 (NDC1) 28.2
 LDTP11844  Protein spinster homolog 1 (SPNS1) 28.2
 LDTP01043  Sorting nexin-2 (SNX2) 27.7
 LDTP07002  Transport and Golgi organization protein 1 homolog (MIA3) 27.5
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 27.3
 LDTP01601  Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) 27.1
 LDTP07667  Transmembrane protein 205 (TMEM205) 27.1
 LDTP03405  Calnexin (CANX) 26.7
 LDTP07537  Metal transporter CNNM4 (CNNM4) 26.7
 LDTP04940  NPC intracellular cholesterol transporter 2 (NPC2) 26.7
 LDTP06945  Sigma intracellular receptor 2 (TMEM97) 26.7
 LDTP08030  Autophagy-related protein 9A (ATG9A) 26.5
 LDTP00405  Etoposide-induced protein 2.4 homolog (EI24) 26.5
 LDTP01217  Metaxin-2 (MTX2) 26.4
 LDTP10533  Sorting nexin-27 (SNX27) 26.4
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 26.2
 LDTP06928  Coiled-coil domain-containing protein 93 (CCDC93) 26.2
 LDTP11291  Transmembrane emp24 domain-containing protein 9 (TMED9) 26.2
 LDTP02048  Cellular tumor antigen p53 (TP53) 26.0
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 26.0
 LDTP12644  Mitochondrial potassium channel ATP-binding subunit (ABCB8) 25.8
 LDTP06499  V-type proton ATPase subunit S1 (ATP6AP1) 25.8
 LDTP01366  Flotillin-1 (FLOT1) 25.6
 LDTP02608  ADP/ATP translocase 1 (SLC25A4) 25.5
 LDTP00590  Protein RER1 (RER1) 25.5
 LDTP07467  Rhomboid domain-containing protein 2 (RHBDD2) 25.3
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 25.1
 LDTP13256  SUN domain-containing protein 2 (SUN2) 24.9
 LDTP08633  Transmembrane protein 192 (TMEM192) 24.9
 LDTP14717  ATP synthase subunit e, mitochondrial (ATP5ME) 24.8
 LDTP06198  Major facilitator superfamily domain-containing protein 10 (MFSD10) 24.8
 LDTP15481  Transmembrane protein 87A (TMEM87A) 24.8
 LDTP06271  ER membrane protein complex subunit 2 (EMC2) 24.4
 LDTP00821  Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) 24.4
 LDTP01309  Renin receptor (ATP6AP2) 24.4
 LDTP03546  Translocator protein (TSPO) 24.4
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 24.1
 LDTP04553  Tricarboxylate transport protein, mitochondrial (SLC25A1) 24.1
 LDTP14174  Sorting nexin-5 (SNX5) 23.9
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP09694  Paraspeckle component 1 (PSPC1) 28.6
GPCR
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15303  Membrane progestin receptor alpha (PAQR7) 27.9
 LDTP14610  Golgi pH regulator B (GPR89B) 27.3
Immunoglobulin
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03772  Basigin (BSG) 31.3
 LDTP05572  Leukocyte surface antigen CD47 (CD47) 31.3
Other
Click to Show/Hide to Show 115 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 99.7
 LDTP02927  Ganglioside GM2 activator (GM2A) 99.7
 LDTP08154  Large ribosomal subunit protein uL10m (MRPL10) 99.7
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 99.7
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 99.7
 LDTP08594  Negative elongation factor C/D (NELFCD) 99.7
 LDTP05160  Nucleobindin-2 (NUCB2) 99.7
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 99.7
 LDTP01494  Protein YIF1A (YIF1A) 99.7
 LDTP01522  Reticulon-3 (RTN3) 99.7
 LDTP12412  Reticulon-4 (RTN4) 99.7
 LDTP13086  Syntaxin-18 (STX18) 99.7
 LDTP14458  Tetraspanin-6 (TSPAN6) 99.7
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 99.7
 LDTP16080  Protein FAM114A2 (FAM114A2) 97.7
 LDTP10255  Protein Hook homolog 2 (HOOK2) 97.7
 LDTP13606  Mammalian ependymin-related protein 1 (EPDR1) 97.0
 LDTP10056  Protein FAM162A (FAM162A) 93.7
 LDTP01359  Dynactin subunit 3 (DCTN3) 78.2
 LDTP01932  Prelamin-A/C (LMNA) 78.2
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 77.7
 LDTP00859  Synaptogyrin-2 (SYNGR2) 76.6
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 74.5
 LDTP14939  Membralin (TMEM259) 74.5
 LDTP00986  Syntaxin-10 (STX10) 74.0
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 73.0
 LDTP05375  Nucleobindin-1 (NUCB1) 70.0
 LDTP01163  Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) 59.7
 LDTP04425  Translocon-associated protein subunit delta (SSR4) 58.1
 LDTP11978  HAUS augmin-like complex subunit 4 (HAUS4) 57.3
 LDTP16006  Optic atrophy 3 protein (OPA3) 57.3
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 56.5
 LDTP06097  Reticulocalbin-2 (RCN2) 56.1
 LDTP07891  Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) 53.4
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 53.4
 LDTP00199  HCLS1-associated protein X-1 (HAX1) 51.6
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 48.8
 LDTP19021  EF-hand calcium-binding domain-containing protein 14 (EFCAB14) 48.5
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 47.8
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 45.9
 LDTP07419  Centromere protein P (CENPP) 45.3
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 44.9
 LDTP19963  TraB domain-containing protein (TRABD) 44.6
 LDTP09787  Nicastrin (NCSTN) 44.0
 LDTP04652  Eukaryotic translation initiation factor 5 (EIF5) 43.4
 LDTP08796  Protein SYS1 homolog (SYS1) 42.8
 LDTP11981  Receptor expression-enhancing protein 4 (REEP4) 41.4
 LDTP03926  Centrin-2 (CETN2) 39.7
 LDTP00887  Calumenin (CALU) 39.4
 LDTP02124  Keratin, type I cytoskeletal 18 (KRT18) 39.4
 LDTP16322  Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) 38.3
 LDTP16285  Transducin beta-like protein 2 (TBL2) 37.5
 LDTP07031  Collectin-12 (COLEC12) 37.3
 LDTP07718  MICOS complex subunit MIC27 (APOOL) 37.3
 LDTP20008  Costars family protein ABRACL (ABRACL) 37.0
 LDTP05641  WASH complex subunit 5 (WASHC5) 37.0
 LDTP05922  Dynactin subunit 2 (DCTN2) 36.8
 LDTP14125  Mitochondrial import inner membrane translocase subunit Tim10 B (TIMM10B) 36.5
 LDTP00417  Programmed cell death protein 5 (PDCD5) 36.5
 LDTP00779  Trans-Golgi network integral membrane protein 2 (TGOLN2) 36.5
 LDTP10924  Prohibitin-2 (PHB2) 35.5
 LDTP05277  Protein SET (SET) 35.5
 LDTP10442  Thioredoxin domain-containing protein 15 (TXNDC15) 35.5
 LDTP09324  Ganglioside-induced differentiation-associated protein 1 (GDAP1) 35.3
 LDTP04703  Tumor protein D52 (TPD52) 34.5
 LDTP11326  FUN14 domain-containing protein 2 (FUNDC2) 34.1
 LDTP06291  ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) 33.8
 LDTP02297  Vimentin (VIM) 33.8
 LDTP00223  26S proteasome non-ATPase regulatory subunit 11 (PSMD11) 33.1
 LDTP13802  DNA replication complex GINS protein PSF2 (GINS2) 32.4
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 32.2
 LDTP09920  Golgi apparatus protein 1 (GLG1) 31.8
 LDTP15398  Protein FAM177A1 (FAM177A1) 31.8
 LDTP01466  HAUS augmin-like complex subunit 5 (HAUS5) 30.7
 LDTP15253  HEAT repeat-containing protein 3 (HEATR3) 30.7
 LDTP04917  Proteasome activator complex subunit 3 (PSME3) 30.5
 LDTP19924  Protein PBDC1 (PBDC1) 30.3
 LDTP01236  Transcription initiation protein SPT3 homolog (SUPT3H) 30.1
 LDTP05530  Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) 29.9
 LDTP02181  Neurofilament medium polypeptide (NEFM) 29.2
 LDTP08689  Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) 28.8
 LDTP04356  Emerin (EMD) 28.8
 LDTP06068  MAGUK p55 subfamily member 2 (MPP2) 28.8
 LDTP08248  NLR family member X1 (NLRX1) 28.4
 LDTP05715  Vesicle transport protein SEC20 (BNIP1) 27.9
 LDTP12629  T-complex protein 11-like protein 1 (TCP11L1) 27.7
 LDTP03065  Lamin-B1 (LMNB1) 27.3
 LDTP10965  Nucleosome assembly protein 1-like 4 (NAP1L4) 27.3
 LDTP00632  Syntaxin-7 (STX7) 27.1
 LDTP14259  Testis-expressed protein 264 (TEX264) 27.1
 LDTP13863  DnaJ homolog subfamily C member 16 (DNAJC16) 26.7
 LDTP12764  MICOS complex subunit MIC19 (CHCHD3) 26.5
 LDTP01167  Reticulon-2 (RTN2) 26.5
 LDTP13091  Ataxin-10 (ATXN10) 26.2
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) 26.2
 LDTP03352  Splicing factor U2AF 65 kDa subunit (U2AF2) 26.2
 LDTP05960  Trophoblast glycoprotein (TPBG) 26.2
 LDTP07934  Synaptic vesicle glycoprotein 2A (SV2A) 25.8
 LDTP05418  UBX domain-containing protein 1 (UBXN1) 25.6
 LDTP04626  UV excision repair protein RAD23 homolog A (RAD23A) 25.6
 LDTP00212  AP-3 complex subunit beta-1 (AP3B1) 25.3
 LDTP10093  Mitochondrial calcium uniporter regulator 1 (MCUR1) 25.3
 LDTP05068  Tropomyosin alpha-4 chain (TPM4) 25.3
 LDTP04207  Heat shock 70 kDa protein 13 (HSPA13) 25.1
 LDTP04094  Large proline-rich protein BAG6 (BAG6) 24.9
 LDTP02180  Neurofilament light polypeptide (NEFL) 24.9
 LDTP12762  Transmembrane protein 161A (TMEM161A) 24.8
 LDTP11525  Kinetochore protein Nuf2 (NUF2) 24.6
 LDTP13837  Trafficking protein particle complex subunit 4 (TRAPPC4) 24.4
 LDTP06527  Alpha-internexin (INA) 24.3
 LDTP01177  Hyaluronan mediated motility receptor (HMMR) 24.1
 LDTP10184  HAUS augmin-like complex subunit 1 (HAUS1) 23.9
 LDTP18132  Protein FAM136A (FAM136A) 23.9
 LDTP15887  Lipase maturation factor 2 (LMF2) 23.8
 LDTP02511  cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) 23.6

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587