Details of the Target

General Information of Target

Target ID LDTP01236
Target Name Transcription initiation protein SPT3 homolog (SUPT3H)
Gene Name SUPT3H
Gene ID 8464
Synonyms
SPT3; Transcription initiation protein SPT3 homolog; SPT3-like protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MNNTAASPMSTATSSSGRSTGKSISFATELQSMMYSLGDARRPLHETAVLVEDVVHTQLI
NLLQQAAEVSQLRGARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVKGIDEDDLL
EDKLSGSNNANKRQKIAQDFLNSIDQTGELLAMFEDDEIDEVKQERMERAERQTRIMDSA
QYAEFCESRQLSFSKKASKFRDWLDCSSMEIKPNVVAMEILAYLAYETVAQLVDLALLVR
QDMVTKAGDPFSHAISATFIQYHNSAESTAACGVEAHSDAIQPCHIREAIRRYSHRIGPL
SPFTNAYRRNGMAFLAC
Target Bioclass
Other
Family
SPT3 family
Subcellular location
Nucleus
Function Probable transcriptional activator.
Uniprot ID
O75486
Ensemble ID
ENST00000371459.6
HGNC ID
HGNC:11466

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
COLO800 SNV: p.E227K .
HCT15 SNV: p.F185L; p.D242Y; p.S278G .
PF382 SNV: p.D249G .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DBIA
 Probe Info  		C268(3.67)  LDD0080  [1]
TFBX
 Probe Info  		N.A.  LDD0027  [2]
IPM
 Probe Info  		N.A.  LDD2156  [3]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [4]
PAL-AfBPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C063
 Probe Info  		10.13  LDD1760  [5]
C112
 Probe Info  		29.45  LDD1799  [5]
C201
 Probe Info  		30.06  LDD1877  [5]
C206
 Probe Info  		16.34  LDD1881  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 PaTu 8988t C268(1.33)  LDD1093  [1]
 LDCM0215  AC10 HCT 116 C268(1.15)  LDD0532  [1]
 LDCM0216  AC100 HEK-293T C268(0.92)  LDD0814  [1]
 LDCM0217  AC101 HEK-293T C268(0.89)  LDD0815  [1]
 LDCM0218  AC102 HEK-293T C268(0.96)  LDD0816  [1]
 LDCM0219  AC103 HEK-293T C268(0.86)  LDD0817  [1]
 LDCM0220  AC104 HEK-293T C268(1.04)  LDD0818  [1]
 LDCM0221  AC105 HEK-293T C268(1.12)  LDD0819  [1]
 LDCM0222  AC106 HEK-293T C268(0.99)  LDD0820  [1]
 LDCM0223  AC107 HEK-293T C268(1.03)  LDD0821  [1]
 LDCM0224  AC108 HEK-293T C268(1.01)  LDD0822  [1]
 LDCM0225  AC109 HEK-293T C268(0.91)  LDD0823  [1]
 LDCM0226  AC11 HCT 116 C268(1.06)  LDD0543  [1]
 LDCM0227  AC110 HEK-293T C268(0.74)  LDD0825  [1]
 LDCM0228  AC111 HEK-293T C268(0.81)  LDD0826  [1]
 LDCM0229  AC112 HEK-293T C268(0.77)  LDD0827  [1]
 LDCM0230  AC113 HEK-293T C268(1.03)  LDD0828  [1]
 LDCM0231  AC114 HEK-293T C268(1.04)  LDD0829  [1]
 LDCM0232  AC115 HEK-293T C268(0.89)  LDD0830  [1]
 LDCM0233  AC116 HEK-293T C268(0.91)  LDD0831  [1]
 LDCM0234  AC117 HEK-293T C268(0.91)  LDD0832  [1]
 LDCM0235  AC118 HEK-293T C268(0.84)  LDD0833  [1]
 LDCM0236  AC119 HEK-293T C268(0.89)  LDD0834  [1]
 LDCM0237  AC12 HCT 116 C268(1.13)  LDD0554  [1]
 LDCM0238  AC120 HEK-293T C268(0.85)  LDD0836  [1]
 LDCM0239  AC121 HEK-293T C268(0.86)  LDD0837  [1]
 LDCM0240  AC122 HEK-293T C268(0.74)  LDD0838  [1]
 LDCM0241  AC123 HEK-293T C268(0.77)  LDD0839  [1]
 LDCM0242  AC124 HEK-293T C268(0.84)  LDD0840  [1]
 LDCM0243  AC125 HEK-293T C268(0.77)  LDD0841  [1]
 LDCM0244  AC126 HEK-293T C268(0.60)  LDD0842  [1]
 LDCM0245  AC127 HEK-293T C268(0.64)  LDD0843  [1]
 LDCM0246  AC128 PaTu 8988t C268(1.35)  LDD1125  [1]
 LDCM0247  AC129 PaTu 8988t C268(1.08)  LDD1126  [1]
 LDCM0249  AC130 PaTu 8988t C268(1.22)  LDD1128  [1]
 LDCM0250  AC131 PaTu 8988t C268(1.31)  LDD1129  [1]
 LDCM0251  AC132 PaTu 8988t C268(1.83)  LDD1130  [1]
 LDCM0252  AC133 PaTu 8988t C268(1.12)  LDD1131  [1]
 LDCM0253  AC134 PaTu 8988t C268(1.56)  LDD1132  [1]
 LDCM0254  AC135 PaTu 8988t C268(1.47)  LDD1133  [1]
 LDCM0255  AC136 PaTu 8988t C268(1.47)  LDD1134  [1]
 LDCM0256  AC137 PaTu 8988t C268(1.41)  LDD1135  [1]
 LDCM0257  AC138 PaTu 8988t C268(1.76)  LDD1136  [1]
 LDCM0258  AC139 PaTu 8988t C268(1.01)  LDD1137  [1]
 LDCM0259  AC14 HCT 116 C268(1.09)  LDD0576  [1]
 LDCM0260  AC140 PaTu 8988t C268(1.42)  LDD1139  [1]
 LDCM0261  AC141 PaTu 8988t C268(1.44)  LDD1140  [1]
 LDCM0262  AC142 PaTu 8988t C268(1.50)  LDD1141  [1]
 LDCM0263  AC143 HEK-293T C268(0.92)  LDD0861  [1]
 LDCM0264  AC144 HEK-293T C268(1.44)  LDD0862  [1]
 LDCM0265  AC145 HEK-293T C268(1.08)  LDD0863  [1]
 LDCM0266  AC146 HEK-293T C268(0.93)  LDD0864  [1]
 LDCM0267  AC147 HEK-293T C268(0.91)  LDD0865  [1]
 LDCM0268  AC148 HEK-293T C268(0.93)  LDD0866  [1]
 LDCM0269  AC149 HEK-293T C268(1.41)  LDD0867  [1]
 LDCM0270  AC15 HCT 116 C268(1.19)  LDD0587  [1]
 LDCM0271  AC150 HEK-293T C268(1.10)  LDD0869  [1]
 LDCM0272  AC151 HEK-293T C268(1.17)  LDD0870  [1]
 LDCM0273  AC152 HEK-293T C268(1.17)  LDD0871  [1]
 LDCM0274  AC153 HEK-293T C268(1.14)  LDD0872  [1]
 LDCM0621  AC154 HEK-293T C268(1.49)  LDD2162  [1]
 LDCM0622  AC155 HEK-293T C268(1.12)  LDD2163  [1]
 LDCM0623  AC156 HEK-293T C268(0.93)  LDD2164  [1]
 LDCM0624  AC157 HEK-293T C268(0.85)  LDD2165  [1]
 LDCM0276  AC17 HCT 116 C268(1.36)  LDD0593  [1]
 LDCM0277  AC18 HCT 116 C268(1.05)  LDD0594  [1]
 LDCM0278  AC19 HCT 116 C268(1.07)  LDD0595  [1]
 LDCM0279  AC2 PaTu 8988t C268(1.14)  LDD1158  [1]
 LDCM0280  AC20 HCT 116 C268(1.10)  LDD0597  [1]
 LDCM0281  AC21 HCT 116 C268(0.81)  LDD0598  [1]
 LDCM0282  AC22 HCT 116 C268(1.04)  LDD0599  [1]
 LDCM0283  AC23 HCT 116 C268(0.94)  LDD0600  [1]
 LDCM0284  AC24 HCT 116 C268(1.13)  LDD0601  [1]
 LDCM0285  AC25 HEK-293T C186(1.12)  LDD1524  [6]
 LDCM0286  AC26 HEK-293T C186(0.97)  LDD1525  [6]
 LDCM0287  AC27 HEK-293T C186(1.03)  LDD1526  [6]
 LDCM0288  AC28 HEK-293T C186(1.07)  LDD1527  [6]
 LDCM0289  AC29 HEK-293T C186(0.95)  LDD1528  [6]
 LDCM0290  AC3 PaTu 8988t C268(1.25)  LDD1169  [1]
 LDCM0291  AC30 HEK-293T C186(1.05)  LDD1530  [6]
 LDCM0292  AC31 HEK-293T C186(1.17)  LDD1531  [6]
 LDCM0293  AC32 HEK-293T C186(0.95)  LDD1532  [6]
 LDCM0294  AC33 HEK-293T C186(0.87)  LDD1533  [6]
 LDCM0295  AC34 HEK-293T C186(1.13)  LDD1534  [6]
 LDCM0296  AC35 HEK-293T C268(0.68)  LDD0894  [1]
 LDCM0297  AC36 HEK-293T C268(0.82)  LDD0895  [1]
 LDCM0298  AC37 HEK-293T C268(0.67)  LDD0896  [1]
 LDCM0299  AC38 HEK-293T C268(0.82)  LDD0897  [1]
 LDCM0300  AC39 HEK-293T C268(0.75)  LDD0898  [1]
 LDCM0301  AC4 PaTu 8988t C268(1.10)  LDD1180  [1]
 LDCM0302  AC40 HEK-293T C268(0.95)  LDD0900  [1]
 LDCM0303  AC41 HEK-293T C268(0.74)  LDD0901  [1]
 LDCM0304  AC42 HEK-293T C268(0.82)  LDD0902  [1]
 LDCM0305  AC43 HEK-293T C268(1.04)  LDD0903  [1]
 LDCM0306  AC44 HEK-293T C268(0.75)  LDD0904  [1]
 LDCM0307  AC45 HEK-293T C268(0.72)  LDD0905  [1]
 LDCM0308  AC46 HEK-293T C268(0.82)  LDD0906  [1]
 LDCM0309  AC47 HEK-293T C268(0.81)  LDD0907  [1]
 LDCM0310  AC48 HEK-293T C268(0.80)  LDD0908  [1]
 LDCM0311  AC49 HEK-293T C268(0.93)  LDD0909  [1]
 LDCM0312  AC5 PaTu 8988t C268(1.57)  LDD1191  [1]
 LDCM0313  AC50 HEK-293T C268(0.81)  LDD0911  [1]
 LDCM0314  AC51 HEK-293T C268(0.72)  LDD0912  [1]
 LDCM0315  AC52 HEK-293T C268(0.73)  LDD0913  [1]
 LDCM0316  AC53 HEK-293T C268(0.85)  LDD0914  [1]
 LDCM0317  AC54 HEK-293T C268(0.71)  LDD0915  [1]
 LDCM0318  AC55 HEK-293T C268(0.77)  LDD0916  [1]
 LDCM0319  AC56 HEK-293T C268(0.83)  LDD0917  [1]
 LDCM0320  AC57 PaTu 8988t C268(1.24)  LDD1199  [1]
 LDCM0321  AC58 PaTu 8988t C268(1.09)  LDD1200  [1]
 LDCM0322  AC59 PaTu 8988t C268(1.17)  LDD1201  [1]
 LDCM0323  AC6 HCT 116 C268(1.16)  LDD0640  [1]
 LDCM0324  AC60 PaTu 8988t C268(1.16)  LDD1203  [1]
 LDCM0325  AC61 PaTu 8988t C268(1.01)  LDD1204  [1]
 LDCM0326  AC62 PaTu 8988t C268(1.21)  LDD1205  [1]
 LDCM0327  AC63 PaTu 8988t C268(0.96)  LDD1206  [1]
 LDCM0328  AC64 PaTu 8988t C268(1.13)  LDD1207  [1]
 LDCM0329  AC65 PaTu 8988t C268(0.97)  LDD1208  [1]
 LDCM0330  AC66 PaTu 8988t C268(0.93)  LDD1209  [1]
 LDCM0331  AC67 PaTu 8988t C268(1.01)  LDD1210  [1]
 LDCM0332  AC68 HEK-293T C268(1.02)  LDD0930  [1]
 LDCM0333  AC69 HEK-293T C268(1.04)  LDD0931  [1]
 LDCM0334  AC7 HCT 116 C268(1.10)  LDD0651  [1]
 LDCM0335  AC70 HEK-293T C268(0.96)  LDD0933  [1]
 LDCM0336  AC71 HEK-293T C268(1.06)  LDD0934  [1]
 LDCM0337  AC72 HEK-293T C268(1.13)  LDD0935  [1]
 LDCM0338  AC73 HEK-293T C268(0.97)  LDD0936  [1]
 LDCM0339  AC74 HEK-293T C268(1.03)  LDD0937  [1]
 LDCM0340  AC75 HEK-293T C268(1.14)  LDD0938  [1]
 LDCM0341  AC76 HEK-293T C268(0.94)  LDD0939  [1]
 LDCM0342  AC77 HEK-293T C268(1.12)  LDD0940  [1]
 LDCM0343  AC78 HEK-293T C268(0.94)  LDD0941  [1]
 LDCM0344  AC79 HEK-293T C268(0.93)  LDD0942  [1]
 LDCM0345  AC8 HCT 116 C268(1.17)  LDD0662  [1]
 LDCM0346  AC80 HEK-293T C268(1.04)  LDD0944  [1]
 LDCM0347  AC81 HEK-293T C268(0.88)  LDD0945  [1]
 LDCM0348  AC82 HEK-293T C268(0.88)  LDD0946  [1]
 LDCM0349  AC83 HEK-293T C268(0.98)  LDD0947  [1]
 LDCM0350  AC84 HEK-293T C268(1.01)  LDD0948  [1]
 LDCM0351  AC85 HEK-293T C268(0.86)  LDD0949  [1]
 LDCM0352  AC86 HEK-293T C268(1.05)  LDD0950  [1]
 LDCM0353  AC87 HEK-293T C268(0.91)  LDD0951  [1]
 LDCM0354  AC88 HEK-293T C268(0.91)  LDD0952  [1]
 LDCM0355  AC89 HEK-293T C268(0.98)  LDD0953  [1]
 LDCM0357  AC90 HEK-293T C268(0.97)  LDD0955  [1]
 LDCM0358  AC91 HEK-293T C268(0.87)  LDD0956  [1]
 LDCM0359  AC92 HEK-293T C268(0.90)  LDD0957  [1]
 LDCM0360  AC93 HEK-293T C268(1.07)  LDD0958  [1]
 LDCM0361  AC94 HEK-293T C268(0.96)  LDD0959  [1]
 LDCM0362  AC95 HEK-293T C268(0.95)  LDD0960  [1]
 LDCM0363  AC96 HEK-293T C268(0.88)  LDD0961  [1]
 LDCM0364  AC97 HEK-293T C268(0.83)  LDD0962  [1]
 LDCM0365  AC98 HEK-293T C268(0.86)  LDD0963  [1]
 LDCM0366  AC99 HEK-293T C268(1.08)  LDD0964  [1]
 LDCM0248  AKOS034007472 HCT 116 C268(1.00)  LDD0565  [1]
 LDCM0356  AKOS034007680 HCT 116 C268(1.18)  LDD0673  [1]
 LDCM0275  AKOS034007705 HCT 116 C268(1.29)  LDD0592  [1]
 LDCM0367  CL1 HEK-293T C186(1.43)  LDD1571  [6]
 LDCM0368  CL10 HEK-293T C186(1.04)  LDD1572  [6]
 LDCM0369  CL100 PaTu 8988t C268(1.41)  LDD1248  [1]
 LDCM0370  CL101 HCT 116 C268(1.16)  LDD0687  [1]
 LDCM0371  CL102 HCT 116 C268(1.00)  LDD0688  [1]
 LDCM0372  CL103 HCT 116 C268(1.06)  LDD0689  [1]
 LDCM0373  CL104 HCT 116 C268(1.20)  LDD0690  [1]
 LDCM0374  CL105 HCT 116 C268(1.00)  LDD0691  [1]
 LDCM0375  CL106 HCT 116 C268(0.81)  LDD0692  [1]
 LDCM0376  CL107 HCT 116 C268(0.82)  LDD0693  [1]
 LDCM0377  CL108 HCT 116 C268(0.88)  LDD0694  [1]
 LDCM0378  CL109 HCT 116 C268(1.01)  LDD0695  [1]
 LDCM0379  CL11 HEK-293T C186(1.11)  LDD1583  [6]
 LDCM0380  CL110 HCT 116 C268(1.08)  LDD0697  [1]
 LDCM0381  CL111 HCT 116 C268(1.03)  LDD0698  [1]
 LDCM0382  CL112 HEK-293T C186(1.03)  LDD1586  [6]
 LDCM0383  CL113 HEK-293T C186(1.22)  LDD1587  [6]
 LDCM0384  CL114 HEK-293T C186(0.92)  LDD1588  [6]
 LDCM0385  CL115 HEK-293T C186(0.99)  LDD1589  [6]
 LDCM0386  CL116 HEK-293T C186(0.93)  LDD1590  [6]
 LDCM0387  CL117 HEK-293T C268(0.72)  LDD0985  [1]
 LDCM0388  CL118 HEK-293T C268(0.78)  LDD0986  [1]
 LDCM0389  CL119 HEK-293T C268(0.82)  LDD0987  [1]
 LDCM0390  CL12 HEK-293T C186(1.01)  LDD1594  [6]
 LDCM0391  CL120 HEK-293T C268(0.77)  LDD0989  [1]
 LDCM0392  CL121 HEK-293T C268(0.77)  LDD0990  [1]
 LDCM0393  CL122 HEK-293T C268(0.82)  LDD0991  [1]
 LDCM0394  CL123 HEK-293T C268(0.78)  LDD0992  [1]
 LDCM0395  CL124 HEK-293T C268(0.82)  LDD0993  [1]
 LDCM0396  CL125 PaTu 8988t C268(1.01)  LDD1275  [1]
 LDCM0397  CL126 PaTu 8988t C268(0.97)  LDD1276  [1]
 LDCM0398  CL127 PaTu 8988t C268(1.08)  LDD1277  [1]
 LDCM0399  CL128 PaTu 8988t C268(1.01)  LDD1278  [1]
 LDCM0400  CL13 HEK-293T C186(1.25)  LDD1604  [6]
 LDCM0401  CL14 HEK-293T C186(1.00)  LDD1605  [6]
 LDCM0402  CL15 HEK-293T C186(1.01)  LDD1606  [6]
 LDCM0403  CL16 HEK-293T C186(1.16)  LDD1607  [6]
 LDCM0404  CL17 HEK-293T C186(1.14)  LDD1608  [6]
 LDCM0405  CL18 HEK-293T C186(1.16)  LDD1609  [6]
 LDCM0406  CL19 HEK-293T C186(1.05)  LDD1610  [6]
 LDCM0407  CL2 HEK-293T C186(0.81)  LDD1611  [6]
 LDCM0408  CL20 HEK-293T C186(0.98)  LDD1612  [6]
 LDCM0409  CL21 HEK-293T C186(1.09)  LDD1613  [6]
 LDCM0410  CL22 HEK-293T C186(1.16)  LDD1614  [6]
 LDCM0411  CL23 HEK-293T C186(1.18)  LDD1615  [6]
 LDCM0412  CL24 HEK-293T C186(1.06)  LDD1616  [6]
 LDCM0413  CL25 HEK-293T C186(0.98)  LDD1617  [6]
 LDCM0414  CL26 HEK-293T C186(1.07)  LDD1618  [6]
 LDCM0415  CL27 HEK-293T C186(1.01)  LDD1619  [6]
 LDCM0416  CL28 HEK-293T C186(1.31)  LDD1620  [6]
 LDCM0417  CL29 HEK-293T C186(1.11)  LDD1621  [6]
 LDCM0418  CL3 HEK-293T C186(1.03)  LDD1622  [6]
 LDCM0419  CL30 HEK-293T C186(1.02)  LDD1623  [6]
 LDCM0420  CL31 HCT 116 C268(0.86)  LDD0737  [1]
 LDCM0421  CL32 HCT 116 C268(0.82)  LDD0738  [1]
 LDCM0422  CL33 HCT 116 C268(1.04)  LDD0739  [1]
 LDCM0423  CL34 HCT 116 C268(0.92)  LDD0740  [1]
 LDCM0424  CL35 HCT 116 C268(0.88)  LDD0741  [1]
 LDCM0425  CL36 HCT 116 C268(0.97)  LDD0742  [1]
 LDCM0426  CL37 HCT 116 C268(0.94)  LDD0743  [1]
 LDCM0428  CL39 HCT 116 C268(0.84)  LDD0745  [1]
 LDCM0429  CL4 HEK-293T C186(0.92)  LDD1633  [6]
 LDCM0430  CL40 HCT 116 C268(1.02)  LDD0747  [1]
 LDCM0431  CL41 HCT 116 C268(0.89)  LDD0748  [1]
 LDCM0432  CL42 HCT 116 C268(0.93)  LDD0749  [1]
 LDCM0433  CL43 HCT 116 C268(0.80)  LDD0750  [1]
 LDCM0434  CL44 HCT 116 C268(0.89)  LDD0751  [1]
 LDCM0435  CL45 HCT 116 C268(1.22)  LDD0752  [1]
 LDCM0436  CL46 HCT 116 C268(1.15)  LDD0753  [1]
 LDCM0437  CL47 HCT 116 C268(0.97)  LDD0754  [1]
 LDCM0438  CL48 HCT 116 C268(1.02)  LDD0755  [1]
 LDCM0439  CL49 HCT 116 C268(1.26)  LDD0756  [1]
 LDCM0440  CL5 HEK-293T C186(0.99)  LDD1644  [6]
 LDCM0441  CL50 HCT 116 C268(1.10)  LDD0758  [1]
 LDCM0442  CL51 HCT 116 C268(1.27)  LDD0759  [1]
 LDCM0443  CL52 HCT 116 C268(1.20)  LDD0760  [1]
 LDCM0444  CL53 HCT 116 C268(1.01)  LDD0761  [1]
 LDCM0445  CL54 HCT 116 C268(0.88)  LDD0762  [1]
 LDCM0446  CL55 HCT 116 C268(1.30)  LDD0763  [1]
 LDCM0447  CL56 HCT 116 C268(1.02)  LDD0764  [1]
 LDCM0448  CL57 HCT 116 C268(1.01)  LDD0765  [1]
 LDCM0449  CL58 HCT 116 C268(1.42)  LDD0766  [1]
 LDCM0450  CL59 HCT 116 C268(1.10)  LDD0767  [1]
 LDCM0451  CL6 HEK-293T C186(1.15)  LDD1654  [6]
 LDCM0452  CL60 HCT 116 C268(1.08)  LDD0769  [1]
 LDCM0453  CL61 HCT 116 C268(1.20)  LDD0770  [1]
 LDCM0454  CL62 HCT 116 C268(1.20)  LDD0771  [1]
 LDCM0455  CL63 HCT 116 C268(1.72)  LDD0772  [1]
 LDCM0456  CL64 HCT 116 C268(3.28)  LDD0773  [1]
 LDCM0457  CL65 HCT 116 C268(1.33)  LDD0774  [1]
 LDCM0458  CL66 HCT 116 C268(2.48)  LDD0775  [1]
 LDCM0459  CL67 HCT 116 C268(2.29)  LDD0776  [1]
 LDCM0460  CL68 HCT 116 C268(1.66)  LDD0777  [1]
 LDCM0461  CL69 HCT 116 C268(1.34)  LDD0778  [1]
 LDCM0462  CL7 HEK-293T C186(1.17)  LDD1665  [6]
 LDCM0463  CL70 HCT 116 C268(1.38)  LDD0780  [1]
 LDCM0464  CL71 HCT 116 C268(1.30)  LDD0781  [1]
 LDCM0465  CL72 HCT 116 C268(1.08)  LDD0782  [1]
 LDCM0466  CL73 HCT 116 C268(1.91)  LDD0783  [1]
 LDCM0467  CL74 HCT 116 C268(1.38)  LDD0784  [1]
 LDCM0469  CL76 HEK-293T C268(0.87)  LDD1067  [1]
 LDCM0470  CL77 HEK-293T C268(0.73)  LDD1068  [1]
 LDCM0471  CL78 HEK-293T C268(0.58)  LDD1069  [1]
 LDCM0472  CL79 HEK-293T C268(0.83)  LDD1070  [1]
 LDCM0473  CL8 HEK-293T C186(0.88)  LDD1676  [6]
 LDCM0474  CL80 HEK-293T C268(0.63)  LDD1072  [1]
 LDCM0475  CL81 HEK-293T C268(0.69)  LDD1073  [1]
 LDCM0476  CL82 HEK-293T C268(0.74)  LDD1074  [1]
 LDCM0477  CL83 HEK-293T C268(0.68)  LDD1075  [1]
 LDCM0478  CL84 HEK-293T C268(0.71)  LDD1076  [1]
 LDCM0479  CL85 HEK-293T C268(0.66)  LDD1077  [1]
 LDCM0480  CL86 HEK-293T C268(0.70)  LDD1078  [1]
 LDCM0481  CL87 HEK-293T C268(0.79)  LDD1079  [1]
 LDCM0482  CL88 HEK-293T C268(0.82)  LDD1080  [1]
 LDCM0483  CL89 HEK-293T C268(0.71)  LDD1081  [1]
 LDCM0484  CL9 HEK-293T C186(1.11)  LDD1687  [6]
 LDCM0485  CL90 HEK-293T C268(0.82)  LDD1083  [1]
 LDCM0486  CL91 PaTu 8988t C268(0.87)  LDD1365  [1]
 LDCM0487  CL92 PaTu 8988t C268(1.08)  LDD1366  [1]
 LDCM0488  CL93 PaTu 8988t C268(1.41)  LDD1367  [1]
 LDCM0489  CL94 PaTu 8988t C268(1.06)  LDD1368  [1]
 LDCM0490  CL95 PaTu 8988t C268(1.62)  LDD1369  [1]
 LDCM0491  CL96 PaTu 8988t C268(1.46)  LDD1370  [1]
 LDCM0492  CL97 PaTu 8988t C268(1.18)  LDD1371  [1]
 LDCM0493  CL98 PaTu 8988t C268(1.50)  LDD1372  [1]
 LDCM0494  CL99 PaTu 8988t C268(0.95)  LDD1373  [1]
 LDCM0495  E2913 HEK-293T C186(1.12)  LDD1698  [6]
 LDCM0468  Fragment33 HCT 116 C268(1.66)  LDD0785  [1]
 LDCM0427  Fragment51 HCT 116 C268(1.63)  LDD0744  [1]
 LDCM0022  KB02 HCT 116 C268(3.67)  LDD0080  [1]
 LDCM0023  KB03 HCT 116 C268(2.44)  LDD0081  [1]
 LDCM0024  KB05 HCT 116 C268(3.43)  LDD0082  [1]

References

1 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
2 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
3 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
4 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
5 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
6 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402