Details of the Probe

General Information of Probe

Probe ID
LDPC0437
Probe Name
C201
Synonyms
Z4225936504
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 325.4
Lipid-water partition coefficient (xlogp) 3.8
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C19H23N3O2
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-2-(5,6,7,8-tetrahydronaphthalen-2-yloxy)acetamide
Canonical SMILES
C#CCCC1(N=N1)CCNC(=O)COC2=CC3=C(CCCC3)C=C2
InChI
InChI=1S/C19H23N3O2/c1-2-3-10-19(21-22-19)11-12-20-18(23)14-24-17-9-8-15-6-4-5-7-16(15)13-17/h1,8-9,13H,3-7,10-12,14H2,(H,20,23)
InChIKey
NXVKOXRRJWPOQM-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

178 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) LDTP06657 34.54  LDD1877 
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 33.82  LDD1877 
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) LDTP02000 31.78  LDD1877 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 46.85  LDD1877 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 48.50  LDD1877 
Acid ceramidase (ASAH1) LDTP05905 94.35  LDD1877 
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) LDTP09814 23.92  LDD1877 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 31.78  LDD1877 
ADP-dependent glucokinase (ADPGK) LDTP11127 44.32  LDD1877 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 90.51  LDD1877 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 25.81  LDD1877 
Alpha-galactosidase A (GLA) LDTP02141 28.64  LDD1877 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 43.41  LDD1877 
Antigen peptide transporter 2 (TAP2) LDTP05409 23.59  LDD1877 
Atlastin-2 (ATL2) LDTP09251 35.75  LDD1877 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 25.11  LDD1877 
ATP-binding cassette sub-family B member 6 (ABCB6) LDTP12303 25.81  LDD1877 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 30.70  LDD1877 
ATPase GET3 (GET3) LDTP00836 30.70  LDD1877 
Beta-galactosidase (GLB1) LDTP02837 29.04  LDD1877 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 24.25  LDD1877 
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPSS1) LDTP00717 25.63  LDD1877 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 34.30  LDD1877 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 79.34  LDD1877 
Calcium-transporting ATPase type 2C member 1 (ATP2C1) LDTP05228 29.04  LDD1877 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 50.21  LDD1877 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 26.35  LDD1877 
Catechol O-methyltransferase (COMT) LDTP03145 46.21  LDD1877 
Ceramide glucosyltransferase (UGCG) LDTP06617 77.71  LDD1877 
Ceramide synthase 2 (CERS2) LDTP10329 42.81  LDD1877 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 44.02  LDD1877 
Choline kinase alpha (CHKA) LDTP03787 44.02  LDD1877 
Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (CSGALNACT2) LDTP08933 99.73  LDD1877 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 31.56  LDD1877 
COP9 signalosome complex subunit 6 (COPS6) LDTP07966 33.82  LDD1877 
Copper-transporting ATPase 1 (ATP7A) LDTP05422 27.67  LDD1877 
Copper-transporting ATPase 2 (ATP7B) LDTP03779 81.01  LDD1877 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 29.45  LDD1877 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 99.73  LDD1877 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 99.73  LDD1877 
Cytochrome b5 type B (CYB5B) LDTP00697 99.73  LDD1877 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 28.64  LDD1877 
Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L) LDTP14427 38.85  LDD1877 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 99.73  LDD1877 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 39.12  LDD1877 
DCN1-like protein 5 (DCUN1D5) LDTP11199 29.04  LDD1877 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 34.06  LDD1877 
Dehydrogenase/reductase SDR family member 7 (DHRS7) LDTP13959 23.59  LDD1877 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 33.36  LDD1877 
Delta(24)-sterol reductase (DHCR24) LDTP06375 44.32  LDD1877 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 39.67  LDD1877 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 26.72  LDD1877 
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) LDTP02362 24.42  LDD1877 
DNA ligase 3 (LIG3) LDTP04334 45.25  LDD1877 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 47.50  LDD1877 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 51.98  LDD1877 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 25.11  LDD1877 
E3 ubiquitin-protein ligase LRSAM1 (LRSAM1) LDTP07672 24.08  LDD1877 
E3 ubiquitin-protein ligase MARCHF5 (MARCHF5) LDTP12757 52.35  LDD1877 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 39.67  LDD1877 
E3 ubiquitin-protein ligase TRIM13 (TRIM13) LDTP01065 57.28  LDD1877 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 27.47  LDD1877 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 27.10  LDD1877 
Endoplasmic reticulum aminopeptidase 2 (ERAP2) LDTP07503 30.70  LDD1877 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 37.79  LDD1877 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 49.87  LDD1877 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 38.05  LDD1877 
Epimerase family protein SDR39U1 (SDR39U1) LDTP16070 29.45  LDD1877 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 38.05  LDD1877 
Ferrochelatase, mitochondrial (FECH) LDTP03198 39.67  LDD1877 
Geranylgeranyl transferase type-2 subunit alpha (RABGGTA) LDTP09845 29.65  LDD1877 
Glutathione hydrolase 7 (GGT7) LDTP13367 37.27  LDD1877 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 50.21  LDD1877 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 44.02  LDD1877 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 47.84  LDD1877 
GPI-anchor transamidase (PIGK) LDTP09835 23.75  LDD1877 
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) LDTP13352 42.52  LDD1877 
Heme A synthase COX15 (COX15) LDTP07931 43.71  LDD1877 
Heme oxygenase 1 (HMOX1) LDTP02359 99.73  LDD1877 
Heme oxygenase 2 (HMOX2) LDTP03540 99.73  LDD1877 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 42.81  LDD1877 
Hexokinase-2 (HK2) LDTP04531 30.70  LDD1877 
Histone-lysine N-methyltransferase NSD2 (NSD2) LDTP01759 28.44  LDD1877 
Holocytochrome c-type synthase (HCCS) LDTP04581 25.81  LDD1877 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 29.24  LDD1877 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 99.73  LDD1877 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 30.70  LDD1877 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 86.82  LDD1877 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 29.04  LDD1877 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 99.73  LDD1877 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 42.22  LDD1877 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 31.78  LDD1877 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 30.91  LDD1877 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 24.42  LDD1877 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 66.26  LDD1877 
Lysosomal acid phosphatase (ACP2) LDTP02539 44.94  LDD1877 
Lysosomal alpha-glucosidase (GAA) LDTP02486 25.81  LDD1877 
Lysosomal protective protein (CTSA) LDTP02505 42.22  LDD1877 
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) LDTP10930 30.48  LDD1877 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 99.73  LDD1877 
Microsomal glutathione S-transferase 2 (MGST2) LDTP10966 26.17  LDD1877 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 38.32  LDD1877 
Mitochondrial intermediate peptidase (MIPEP) LDTP10981 29.86  LDD1877 
Mitochondrial Rho GTPase 2 (RHOT2) LDTP08596 33.13  LDD1877 
Mitochondrial ubiquitin ligase activator of NFKB 1 (MUL1) LDTP10038 34.30  LDD1877 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 29.65  LDD1877 
Mitofusin-1 (MFN1) LDTP08530 32.67  LDD1877 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 36.76  LDD1877 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 86.82  LDD1877 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 89.88  LDD1877 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 30.91  LDD1877 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 99.73  LDD1877 
NADH dehydrogenase 1 beta subcomplex subunit 4 (NDUFB4) LDTP01514 26.91  LDD1877 
NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) LDTP01502 23.92  LDD1877 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 60.55  LDD1877 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 99.73  LDD1877 
NADP-dependent malic enzyme (ME1) LDTP04164 27.47  LDD1877 
NADPH--cytochrome P450 reductase (POR) LDTP02848 27.47  LDD1877 
Pachytene checkpoint protein 2 homolog (TRIP13) LDTP06432 26.54  LDD1877 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 99.73  LDD1877 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 46.53  LDD1877 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 26.17  LDD1877 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 31.34  LDD1877 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 31.56  LDD1877 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 29.24  LDD1877 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 32.90  LDD1877 
Phosphatidylserine synthase 2 (PTDSS2) LDTP11284 27.86  LDD1877 
Pirin (PIR) LDTP00325 28.25  LDD1877 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 31.78  LDD1877 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 23.59  LDD1877 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 86.22  LDD1877 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 31.12  LDD1877 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 28.44  LDD1877 
Prostaglandin reductase 3 (PTGR3) LDTP15422 99.73  LDD1877 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 57.68  LDD1877 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 32.22  LDD1877 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 36.00  LDD1877 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 35.02  LDD1877 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 25.81  LDD1877 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 29.65  LDD1877 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 99.73  LDD1877 
Rab-like protein 3 (RABL3) LDTP06986 30.06  LDD1877 
Ras-related protein Rab-24 (RAB24) LDTP10020 36.00  LDD1877 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 54.95  LDD1877 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 55.72  LDD1877 
Retinol dehydrogenase 13 (RDH13) LDTP09061 25.99  LDD1877 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 48.17  LDD1877 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 31.78  LDD1877 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 39.95  LDD1877 
SEC23-interacting protein (SEC23IP) LDTP14311 30.91  LDD1877 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 29.86  LDD1877 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 27.47  LDD1877 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 36.00  LDD1877 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 29.24  LDD1877 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 34.54  LDD1877 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 29.45  LDD1877 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 38.32  LDD1877 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 86.22  LDD1877 
Squalene monooxygenase (SQLE) LDTP06142 34.78  LDD1877 
Squalene synthase (FDFT1) LDTP03842 32.22  LDD1877 
Thimet oligopeptidase (THOP1) LDTP04542 32.67  LDD1877 
Thiol S-methyltransferase TMT1B (TMT1B) LDTP15155 25.46  LDD1877 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 32.00  LDD1877 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 32.00  LDD1877 
TLC domain-containing protein 1 (TLCD1) LDTP10182 32.90  LDD1877 
Trans-3-hydroxy-L-proline dehydratase (L3HYPDH) LDTP10267 26.35  LDD1877 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 30.48  LDD1877 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 41.07  LDD1877 
Trimethyllysine dioxygenase, mitochondrial (TMLHE) LDTP12679 25.81  LDD1877 
Triple functional domain protein (TRIO) LDTP01368 25.28  LDD1877 
Tubulin--tyrosine ligase-like protein 12 (TTLL12) LDTP06067 63.56  LDD1877 
Ubiquitin carboxyl-terminal hydrolase 24 (USP24) LDTP13720 26.91  LDD1877 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 48.50  LDD1877 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 37.53  LDD1877 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 26.91  LDD1877 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 29.45  LDD1877 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 34.30  LDD1877 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 44.63  LDD1877 
------------------------------------------------------------------------------------
⏷ Show the Full List of 178 Enzyme
128 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 44.94  LDD1877 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 27.10  LDD1877 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 37.79  LDD1877 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 25.46  LDD1877 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 26.17  LDD1877 
Amyloid-beta precursor protein (APP) LDTP02071 28.44  LDD1877 
Anoctamin-10 (ANO10) LDTP12704 29.86  LDD1877 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 99.73  LDD1877 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 24.76  LDD1877 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 62.25  LDD1877 
Autophagy-related protein 9A (ATG9A) LDTP08030 26.54  LDD1877 
B-cell receptor-associated protein 31 (BCAP31) LDTP04426 32.22  LDD1877 
Calnexin (CANX) LDTP03405 26.72  LDD1877 
Cellular tumor antigen p53 (TP53) LDTP02048 25.99  LDD1877 
Chloride channel CLIC-like protein 1 (CLCC1) LDTP10804 31.56  LDD1877 
Coiled-coil domain-containing protein 93 (CCDC93) LDTP06928 26.17  LDD1877 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 73.52  LDD1877 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 70.52  LDD1877 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 99.73  LDD1877 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 99.73  LDD1877 
Derlin-2 (DERL2) LDTP11634 40.22  LDD1877 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 32.45  LDD1877 
Endophilin-B1 (SH3GLB1) LDTP13953 70.52  LDD1877 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 37.01  LDD1877 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 99.73  LDD1877 
ER membrane protein complex subunit 2 (EMC2) LDTP06271 24.42  LDD1877 
Etoposide-induced protein 2.4 homolog (EI24) LDTP00405 26.54  LDD1877 
Flotillin-1 (FLOT1) LDTP01366 25.63  LDD1877 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 88.65  LDD1877 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 35.26  LDD1877 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 33.36  LDD1877 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 36.50  LDD1877 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 68.12  LDD1877 
Importin-4 (IPO4) LDTP09515 35.02  LDD1877 
Integral membrane protein 2C (ITM2C) LDTP12451 36.76  LDD1877 
Intermembrane lipid transfer protein VPS13A (VPS13A) LDTP10769 29.24  LDD1877 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 31.78  LDD1877 
Lysosome membrane protein 2 (SCARB2) LDTP06034 57.68  LDD1877 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 35.51  LDD1877 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 48.17  LDD1877 
Major facilitator superfamily domain-containing protein 10 (MFSD10) LDTP06198 24.76  LDD1877 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 28.44  LDD1877 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 99.73  LDD1877 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 48.17  LDD1877 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 99.73  LDD1877 
Metal cation symporter ZIP14 (SLC39A14) LDTP06293 34.78  LDD1877 
Metal transporter CNNM4 (CNNM4) LDTP07537 26.72  LDD1877 
Metaxin-1 (MTX1) LDTP05900 98.36  LDD1877 
Metaxin-2 (MTX2) LDTP01217 26.35  LDD1877 
MICOS complex subunit MIC26 (APOO) LDTP11250 49.18  LDD1877 
MICOS complex subunit MIC60 (IMMT) LDTP06660 28.64  LDD1877 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 35.26  LDD1877 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 29.04  LDD1877 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 36.25  LDD1877 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 49.52  LDD1877 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 24.08  LDD1877 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 51.63  LDD1877 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 99.73  LDD1877 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD1877 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 29.04  LDD1877 
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 24.42  LDD1877 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 70.03  LDD1877 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 31.12  LDD1877 
Mitochondrial potassium channel ATP-binding subunit (ABCB8) LDTP12644 25.81  LDD1877 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 80.45  LDD1877 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 72.50  LDD1877 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 25.11  LDD1877 
Mitoguardin 1 (MIGA1) LDTP09028 43.41  LDD1877 
Mpv17-like protein 2 (MPV17L2) LDTP14952 41.07  LDD1877 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 81.01  LDD1877 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 26.72  LDD1877 
Nucleoporin NDC1 (NDC1) LDTP11213 28.25  LDD1877 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 48.84  LDD1877 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 41.64  LDD1877 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 27.28  LDD1877 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 31.34  LDD1877 
PRA1 family protein 2 (PRAF2) LDTP01060 32.90  LDD1877 
Prosaposin (PSAP) LDTP02215 99.73  LDD1877 
Protein GPR107 (GPR107) LDTP07236 95.01  LDD1877 
Protein Mpv17 (MPV17) LDTP03869 28.44  LDD1877 
Protein RER1 (RER1) LDTP00590 25.46  LDD1877 
Protein RFT1 homolog (RFT1) LDTP10073 30.27  LDD1877 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 41.07  LDD1877 
Protein spinster homolog 1 (SPNS1) LDTP11844 28.25  LDD1877 
Protein tweety homolog 3 (TTYH3) LDTP11615 99.73  LDD1877 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 66.26  LDD1877 
Renin receptor (ATP6AP2) LDTP01309 24.42  LDD1877 
Rhomboid domain-containing protein 2 (RHBDD2) LDTP07467 25.28  LDD1877 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 39.95  LDD1877 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 99.73  LDD1877 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 26.72  LDD1877 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 58.08  LDD1877 
Solute carrier family 25 member 16 (SLC25A16) LDTP14636 48.17  LDD1877 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 99.73  LDD1877 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 99.73  LDD1877 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 29.04  LDD1877 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 28.64  LDD1877 
Sorting nexin-19 (SNX19) LDTP09788 33.59  LDD1877 
Sorting nexin-2 (SNX2) LDTP01043 27.67  LDD1877 
Sorting nexin-27 (SNX27) LDTP10533 26.35  LDD1877 
Sorting nexin-5 (SNX5) LDTP14174 23.92  LDD1877 
Stomatin (STOM) LDTP03380 36.76  LDD1877 
SUN domain-containing protein 2 (SUN2) LDTP13256 24.93  LDD1877 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 83.29  LDD1877 
Tetraspanin-3 (TSPAN3) LDTP16813 99.73  LDD1877 
Translocator protein (TSPO) LDTP03546 24.42  LDD1877 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD1877 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 63.56  LDD1877 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 25.99  LDD1877 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 44.94  LDD1877 
Transmembrane emp24 domain-containing protein 9 (TMED9) LDTP11291 26.17  LDD1877 
Transmembrane protein 126A (TMEM126A) LDTP15948 99.73  LDD1877 
Transmembrane protein 14C (TMEM14C) LDTP12979 28.44  LDD1877 
Transmembrane protein 192 (TMEM192) LDTP08633 24.93  LDD1877 
Transmembrane protein 199 (TMEM199) LDTP08881 53.45  LDD1877 
Transmembrane protein 201 (TMEM201) LDTP07058 36.25  LDD1877 
Transmembrane protein 205 (TMEM205) LDTP07667 27.10  LDD1877 
Transmembrane protein 230 (TMEM230) LDTP10065 35.02  LDD1877 
Transmembrane protein 33 (TMEM33) LDTP04787 30.48  LDD1877 
Transmembrane protein 87A (TMEM87A) LDTP15481 24.76  LDD1877 
Transport and Golgi organization protein 1 homolog (MIA3) LDTP07002 27.47  LDD1877 
Tricarboxylate transport protein, mitochondrial (SLC25A1) LDTP04553 24.08  LDD1877 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 52.71  LDD1877 
V-type proton ATPase subunit S1 (ATP6AP1) LDTP06499 25.81  LDD1877 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 94.35  LDD1877 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 99.73  LDD1877 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 70.52  LDD1877 
Wolframin (WFS1) LDTP01380 36.00  LDD1877 
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⏷ Show the Full List of 128 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Paraspeckle component 1 (PSPC1) LDTP09694 28.64  LDD1877 
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2 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Golgi pH regulator B (GPR89B) LDTP14610 27.28  LDD1877 
Membrane progestin receptor alpha (PAQR7) LDTP15303 27.86  LDD1877 
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2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 31.34  LDD1877 
Leukocyte surface antigen CD47 (CD47) LDTP05572 31.34  LDD1877 
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115 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 33.13  LDD1877 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 33.82  LDD1877 
Alpha-internexin (INA) LDTP06527 24.25  LDD1877 
AP-3 complex subunit beta-1 (AP3B1) LDTP00212 25.28  LDD1877 
Ataxin-10 (ATXN10) LDTP13091 26.17  LDD1877 
Calumenin (CALU) LDTP00887 39.40  LDD1877 
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) LDTP02511 23.59  LDD1877 
Centrin-2 (CETN2) LDTP03926 39.67  LDD1877 
Centromere protein P (CENPP) LDTP07419 45.25  LDD1877 
Clustered mitochondria protein homolog (CLUH) LDTP14486 32.22  LDD1877 
Collectin-12 (COLEC12) LDTP07031 37.27  LDD1877 
Costars family protein ABRACL (ABRACL) LDTP20008 37.01  LDD1877 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 99.73  LDD1877 
DNA replication complex GINS protein PSF2 (GINS2) LDTP13802 32.45  LDD1877 
DnaJ homolog subfamily C member 16 (DNAJC16) LDTP13863 26.72  LDD1877 
Dynactin subunit 2 (DCTN2) LDTP05922 36.76  LDD1877 
Dynactin subunit 3 (DCTN3) LDTP01359 78.25  LDD1877 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 28.84  LDD1877 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 48.50  LDD1877 
Emerin (EMD) LDTP04356 28.84  LDD1877 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 77.71  LDD1877 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 74.54  LDD1877 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 43.41  LDD1877 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 34.06  LDD1877 
Ganglioside GM2 activator (GM2A) LDTP02927 99.73  LDD1877 
Ganglioside-induced differentiation-associated protein 1 (GDAP1) LDTP09324 35.26  LDD1877 
Golgi apparatus protein 1 (GLG1) LDTP09920 31.78  LDD1877 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 48.84  LDD1877 
HAUS augmin-like complex subunit 1 (HAUS1) LDTP10184 23.92  LDD1877 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 57.28  LDD1877 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 30.70  LDD1877 
HCLS1-associated protein X-1 (HAX1) LDTP00199 51.63  LDD1877 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 30.70  LDD1877 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 25.11  LDD1877 
Hyaluronan mediated motility receptor (HMMR) LDTP01177 24.08  LDD1877 
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) LDTP05530 29.86  LDD1877 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 53.45  LDD1877 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 39.40  LDD1877 
Kinetochore protein Nuf2 (NUF2) LDTP11525 24.59  LDD1877 
Lamin-B1 (LMNB1) LDTP03065 27.28  LDD1877 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 45.89  LDD1877 
Large proline-rich protein BAG6 (BAG6) LDTP04094 24.93  LDD1877 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 99.73  LDD1877 
Lipase maturation factor 2 (LMF2) LDTP15887 23.75  LDD1877 
MAGUK p55 subfamily member 2 (MPP2) LDTP06068 28.84  LDD1877 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 97.01  LDD1877 
Membralin (TMEM259) LDTP14939 74.54  LDD1877 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 53.45  LDD1877 
MICOS complex subunit MIC19 (CHCHD3) LDTP12764 26.54  LDD1877 
MICOS complex subunit MIC27 (APOOL) LDTP07718 37.27  LDD1877 
Mitochondrial calcium uniporter regulator 1 (MCUR1) LDTP10093 25.28  LDD1877 
Mitochondrial import inner membrane translocase subunit Tim10 B (TIMM10B) LDTP14125 36.50  LDD1877 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 38.32  LDD1877 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD1877 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 99.73  LDD1877 
Negative elongation factor C/D (NELFCD) LDTP08594 99.73  LDD1877 
Neurofilament light polypeptide (NEFL) LDTP02180 24.93  LDD1877 
Neurofilament medium polypeptide (NEFM) LDTP02181 29.24  LDD1877 
Nicastrin (NCSTN) LDTP09787 44.02  LDD1877 
NLR family member X1 (NLRX1) LDTP08248 28.44  LDD1877 
Nucleobindin-1 (NUCB1) LDTP05375 70.03  LDD1877 
Nucleobindin-2 (NUCB2) LDTP05160 99.73  LDD1877 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 27.28  LDD1877 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 73.01  LDD1877 
Optic atrophy 3 protein (OPA3) LDTP16006 57.28  LDD1877 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 99.73  LDD1877 
Prelamin-A/C (LMNA) LDTP01932 78.25  LDD1877 
Programmed cell death protein 5 (PDCD5) LDTP00417 36.50  LDD1877 
Prohibitin-2 (PHB2) LDTP10924 35.51  LDD1877 
Proteasome activator complex subunit 3 (PSME3) LDTP04917 30.48  LDD1877 
Protein FAM114A2 (FAM114A2) LDTP16080 97.68  LDD1877 
Protein FAM136A (FAM136A) LDTP18132 23.92  LDD1877 
Protein FAM162A (FAM162A) LDTP10056 93.70  LDD1877 
Protein FAM177A1 (FAM177A1) LDTP15398 31.78  LDD1877 
Protein Hook homolog 2 (HOOK2) LDTP10255 97.68  LDD1877 
Protein jagunal homolog 1 (JAGN1) LDTP08904 56.49  LDD1877 
Protein PBDC1 (PBDC1) LDTP19924 30.27  LDD1877 
Protein SET (SET) LDTP05277 35.51  LDD1877 
Protein SYS1 homolog (SYS1) LDTP08796 42.81  LDD1877 
Protein YIF1A (YIF1A) LDTP01494 99.73  LDD1877 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 41.36  LDD1877 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 26.17  LDD1877 
Reticulocalbin-2 (RCN2) LDTP06097 56.10  LDD1877 
Reticulon-2 (RTN2) LDTP01167 26.54  LDD1877 
Reticulon-3 (RTN3) LDTP01522 99.73  LDD1877 
Reticulon-4 (RTN4) LDTP12412 99.73  LDD1877 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 47.84  LDD1877 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 44.94  LDD1877 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 26.17  LDD1877 
Synaptic vesicle glycoprotein 2A (SV2A) LDTP07934 25.81  LDD1877 
Synaptogyrin-2 (SYNGR2) LDTP00859 76.64  LDD1877 
Syntaxin-10 (STX10) LDTP00986 74.03  LDD1877 
Syntaxin-18 (STX18) LDTP13086 99.73  LDD1877 
Syntaxin-7 (STX7) LDTP00632 27.10  LDD1877 
T-complex protein 11-like protein 1 (TCP11L1) LDTP12629 27.67  LDD1877 
Testis-expressed protein 264 (TEX264) LDTP14259 27.10  LDD1877 
Tetraspanin-6 (TSPAN6) LDTP14458 99.73  LDD1877 
Thioredoxin domain-containing protein 15 (TXNDC15) LDTP10442 35.51  LDD1877 
TraB domain-containing protein (TRABD) LDTP19963 44.63  LDD1877 
Trafficking protein particle complex subunit 4 (TRAPPC4) LDTP13837 24.42  LDD1877 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 36.50  LDD1877 
Transcription initiation protein SPT3 homolog (SUPT3H) LDTP01236 30.06  LDD1877 
Transducin beta-like protein 2 (TBL2) LDTP16285 37.53  LDD1877 
Translocon-associated protein subunit delta (SSR4) LDTP04425 58.08  LDD1877 
Transmembrane protein 161A (TMEM161A) LDTP12762 24.76  LDD1877 
Trophoblast glycoprotein (TPBG) LDTP05960 26.17  LDD1877 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 25.28  LDD1877 
Tumor protein D52 (TPD52) LDTP04703 34.54  LDD1877 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 99.73  LDD1877 
Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) LDTP01163 59.71  LDD1877 
UBX domain-containing protein 1 (UBXN1) LDTP05418 25.63  LDD1877 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 25.63  LDD1877 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 27.86  LDD1877 
Vimentin (VIM) LDTP02297 33.82  LDD1877 
WASH complex subunit 5 (WASHC5) LDTP05641 37.01  LDD1877 
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⏷ Show the Full List of 115 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1877 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587