Target ID	LDTP01060
Target Name	PRA1 family protein 2 (PRAF2)
Gene Name	PRAF2
Gene ID	11230
Synonyms	PRA1 family protein 2
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MSEVRLPPLRALDDFVLGSARLAAPDPCDPQRWCHRVINNLLYYQTNYLLCFGIGLALAG YVRPLHTLLSALVVAVALGVLVWAAETRAAVRRCRRSHPAACLAAVLAVGLLVLWVAGGA CTFLFSIAGPVLLILVHASLRLRNLKNKIENKIESIGLKRTPMGLLLEALGQEQEAGS
Target Bioclass	Transporter and channel
Family	PRA1 family
Subcellular location	Endosome membrane
Function	May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptotic role in cerulenin-induced neuroblastoma apoptosis.
Uniprot ID	O60831
Ensemble ID	ENST00000553851.3
HGNC ID	HGNC:28911

Probe name		Structure	Binding Site(Ratio)	Interaction ID	Ref
HDSF-alk  Probe Info			4.09	LDD0197	[1]
CHEMBL5175495  Probe Info			15.65	LDD0196	[2]
FBP2  Probe Info			3.45	LDD0317	[3]
m-APA  Probe Info			12.59	LDD0403	[4]
Curcusone 37  Probe Info			2.20	LDD0188	[5]
Johansson_61  Probe Info			_(4.08)	LDD1489	[6]
AHL-Pu-1  Probe Info			C28(2.86)	LDD0171	[7]
HPAP  Probe Info			3.67	LDD0062	[8]
Alkyne-RA190  Probe Info			12.91	LDD0299	[9]
EA-probe  Probe Info			C28(1.06)	LDD2210	[10]
DBIA  Probe Info			C28(62.78)	LDD0209	[11]
4-Iodoacetamidophenylacetylene  Probe Info			N.A.	LDD0038	[12]
IA-alkyne  Probe Info			N.A.	LDD0165	[13]
Lodoacetamide azide  Probe Info			N.A.	LDD0037	[12]
JW-RF-010  Probe Info			C34(0.00); C28(0.00)	LDD0026	[14]
NAIA_4  Probe Info			N.A.	LDD2226	[15]
TFBX  Probe Info			C34(0.00); C28(0.00)	LDD0027	[14]
WYneN  Probe Info			N.A.	LDD0021	[16]
WYneO  Probe Info			N.A.	LDD0022	[16]
DA-P3  Probe Info			N.A.	LDD0178	[17]
Compound 10  Probe Info			N.A.	LDD2216	[18]
Compound 11  Probe Info			N.A.	LDD2213	[18]
IPM  Probe Info			N.A.	LDD0005	[16]
STPyne  Probe Info			N.A.	LDD0009	[16]
Phosphinate-6  Probe Info			N.A.	LDD0018	[19]
Acrolein  Probe Info			N.A.	LDD0217	[20]
Cinnamaldehyde  Probe Info			N.A.	LDD0220	[20]
Crotonaldehyde  Probe Info			N.A.	LDD0219	[20]
Methacrolein  Probe Info			N.A.	LDD0218	[20]

Probe name		Structure	Binding Site(Ratio)	Interaction ID	Ref
DR-1  Probe Info			2.66	LDD0398	[21]
C027  Probe Info			7.94	LDD1733	[22]
C040  Probe Info			16.00	LDD1740	[22]
C055  Probe Info			15.45	LDD1752	[22]
C056  Probe Info			33.36	LDD1753	[22]
C063  Probe Info			11.00	LDD1760	[22]
C091  Probe Info			10.48	LDD1782	[22]
C092  Probe Info			16.68	LDD1783	[22]
C094  Probe Info			25.28	LDD1785	[22]
C112  Probe Info			18.90	LDD1799	[22]
C134  Probe Info			35.75	LDD1816	[22]
C169  Probe Info			28.84	LDD1849	[22]
C194  Probe Info			10.85	LDD1870	[22]
C196  Probe Info			11.63	LDD1872	[22]
C198  Probe Info			12.13	LDD1874	[22]
C201  Probe Info			32.90	LDD1877	[22]
C225  Probe Info			5.54	LDD1898	[22]
C228  Probe Info			33.36	LDD1901	[22]
C231  Probe Info			22.01	LDD1904	[22]
C232  Probe Info			34.30	LDD1905	[22]
C235  Probe Info			30.91	LDD1908	[22]
C246  Probe Info			16.56	LDD1919	[22]
C251  Probe Info			49.52	LDD1924	[22]
C252  Probe Info			13.64	LDD1925	[22]
C273  Probe Info			5.78	LDD1943	[22]
C275  Probe Info			6.28	LDD1945	[22]
C277  Probe Info			14.42	LDD1947	[22]
C278  Probe Info			53.82	LDD1948	[22]
C285  Probe Info			22.01	LDD1955	[22]
C289  Probe Info			32.00	LDD1959	[22]
C293  Probe Info			24.08	LDD1963	[22]
C296  Probe Info			14.72	LDD1966	[22]
C339  Probe Info			7.31	LDD2002	[22]
C343  Probe Info			13.00	LDD2005	[22]
C348  Probe Info			11.39	LDD2009	[22]
C349  Probe Info			19.03	LDD2010	[22]
C350  Probe Info			40.22	LDD2011	[22]
C362  Probe Info			58.89	LDD2023	[22]
C364  Probe Info			17.51	LDD2025	[22]
C366  Probe Info			7.31	LDD2027	[22]
C388  Probe Info			53.45	LDD2047	[22]
C407  Probe Info			15.35	LDD2064	[22]
OEA-DA  Probe Info			3.38	LDD0046	[23]

Competitor ID	Name	Cell line	Binding Site(Ratio)	Interaction ID	Ref
LDCM0026	4SU-RNA+native RNA	DM93	C28(2.86)	LDD0171	[7]
LDCM0214	AC1	HCT 116	C28(1.67)	LDD0531	[24]
LDCM0215	AC10	HCT 116	C28(1.13)	LDD0532	[24]
LDCM0216	AC100	HCT 116	C28(0.96)	LDD0533	[24]
LDCM0217	AC101	HCT 116	C28(1.12)	LDD0534	[24]
LDCM0218	AC102	HCT 116	C28(1.05)	LDD0535	[24]
LDCM0219	AC103	HCT 116	C28(1.39)	LDD0536	[24]
LDCM0220	AC104	HCT 116	C28(1.34)	LDD0537	[24]
LDCM0221	AC105	HCT 116	C28(1.28)	LDD0538	[24]
LDCM0222	AC106	HCT 116	C28(1.36)	LDD0539	[24]
LDCM0223	AC107	HCT 116	C28(1.35)	LDD0540	[24]
LDCM0224	AC108	HCT 116	C28(0.89)	LDD0541	[24]
LDCM0225	AC109	HCT 116	C28(0.96)	LDD0542	[24]
LDCM0226	AC11	HCT 116	C28(1.23)	LDD0543	[24]
LDCM0227	AC110	HCT 116	C28(0.95)	LDD0544	[24]
LDCM0228	AC111	HCT 116	C28(0.97)	LDD0545	[24]
LDCM0229	AC112	HCT 116	C28(1.17)	LDD0546	[24]
LDCM0230	AC113	HCT 116	C28(1.03)	LDD0547	[24]
LDCM0231	AC114	HCT 116	C28(1.37)	LDD0548	[24]
LDCM0232	AC115	HCT 116	C28(1.50)	LDD0549	[24]
LDCM0233	AC116	HCT 116	C28(1.64)	LDD0550	[24]
LDCM0234	AC117	HCT 116	C28(1.36)	LDD0551	[24]
LDCM0235	AC118	HCT 116	C28(1.17)	LDD0552	[24]
LDCM0236	AC119	HCT 116	C28(1.46)	LDD0553	[24]
LDCM0237	AC12	HCT 116	C28(1.12)	LDD0554	[24]
LDCM0238	AC120	HCT 116	C28(1.38)	LDD0555	[24]
LDCM0239	AC121	HCT 116	C28(1.24)	LDD0556	[24]
LDCM0240	AC122	HCT 116	C28(1.14)	LDD0557	[24]
LDCM0241	AC123	HCT 116	C28(1.23)	LDD0558	[24]
LDCM0242	AC124	HCT 116	C28(1.15)	LDD0559	[24]
LDCM0243	AC125	HCT 116	C28(1.28)	LDD0560	[24]
LDCM0244	AC126	HCT 116	C28(1.69)	LDD0561	[24]
LDCM0245	AC127	HCT 116	C28(1.46)	LDD0562	[24]
LDCM0246	AC128	HCT 116	C28(1.47)	LDD0563	[24]
LDCM0247	AC129	HCT 116	C28(0.86)	LDD0564	[24]
LDCM0249	AC130	HCT 116	C28(1.29)	LDD0566	[24]
LDCM0250	AC131	HCT 116	C28(0.92)	LDD0567	[24]
LDCM0251	AC132	HCT 116	C28(0.91)	LDD0568	[24]
LDCM0252	AC133	HCT 116	C28(1.11)	LDD0569	[24]
LDCM0253	AC134	HCT 116	C28(1.21)	LDD0570	[24]
LDCM0254	AC135	HCT 116	C28(1.15)	LDD0571	[24]
LDCM0255	AC136	HCT 116	C28(1.21)	LDD0572	[24]
LDCM0256	AC137	HCT 116	C28(1.01)	LDD0573	[24]
LDCM0257	AC138	HCT 116	C28(1.05)	LDD0574	[24]
LDCM0258	AC139	HCT 116	C28(1.09)	LDD0575	[24]
LDCM0259	AC14	HCT 116	C28(1.23)	LDD0576	[24]
LDCM0260	AC140	HCT 116	C28(1.19)	LDD0577	[24]
LDCM0261	AC141	HCT 116	C28(1.10)	LDD0578	[24]
LDCM0262	AC142	HCT 116	C28(0.85)	LDD0579	[24]
LDCM0263	AC143	HEK-293T	C28(1.15)	LDD0861	[24]
LDCM0264	AC144	HEK-293T	C28(1.33)	LDD0862	[24]
LDCM0265	AC145	HEK-293T	C28(1.36)	LDD0863	[24]
LDCM0266	AC146	HEK-293T	C28(1.45)	LDD0864	[24]
LDCM0267	AC147	HEK-293T	C28(1.29)	LDD0865	[24]
LDCM0268	AC148	HEK-293T	C28(0.98)	LDD0866	[24]
LDCM0269	AC149	HEK-293T	C28(1.02)	LDD0867	[24]
LDCM0270	AC15	HCT 116	C28(1.22)	LDD0587	[24]
LDCM0271	AC150	HEK-293T	C28(1.13)	LDD0869	[24]
LDCM0272	AC151	HEK-293T	C28(1.13)	LDD0870	[24]
LDCM0273	AC152	HEK-293T	C28(1.13)	LDD0871	[24]
LDCM0274	AC153	HEK-293T	C28(1.24)	LDD0872	[24]
LDCM0621	AC154	HEK-293T	C28(1.25)	LDD2162	[24]
LDCM0622	AC155	HEK-293T	C28(1.13)	LDD2163	[24]
LDCM0623	AC156	HEK-293T	C28(1.40)	LDD2164	[24]
LDCM0624	AC157	HEK-293T	C28(1.71)	LDD2165	[24]
LDCM0276	AC17	HCT 116	C28(0.97)	LDD0593	[24]
LDCM0277	AC18	HCT 116	C28(1.12)	LDD0594	[24]
LDCM0278	AC19	HCT 116	C28(1.29)	LDD0595	[24]
LDCM0279	AC2	HCT 116	C28(1.77)	LDD0596	[24]
LDCM0280	AC20	HCT 116	C28(1.00)	LDD0597	[24]
LDCM0281	AC21	HCT 116	C28(1.60)	LDD0598	[24]
LDCM0282	AC22	HCT 116	C28(1.27)	LDD0599	[24]
LDCM0283	AC23	HCT 116	C28(1.09)	LDD0600	[24]
LDCM0284	AC24	HCT 116	C28(1.03)	LDD0601	[24]
LDCM0285	AC25	HEK-293T	C28(1.19)	LDD0883	[24]
LDCM0286	AC26	HEK-293T	C28(1.32)	LDD0884	[24]
LDCM0287	AC27	HEK-293T	C28(1.40)	LDD0885	[24]
LDCM0288	AC28	HEK-293T	C28(1.47)	LDD0886	[24]
LDCM0289	AC29	HEK-293T	C28(1.37)	LDD0887	[24]
LDCM0290	AC3	HCT 116	C28(1.66)	LDD0607	[24]
LDCM0291	AC30	HEK-293T	C28(1.34)	LDD0889	[24]
LDCM0292	AC31	HEK-293T	C28(1.07)	LDD0890	[24]
LDCM0293	AC32	HEK-293T	C28(1.16)	LDD0891	[24]
LDCM0294	AC33	HEK-293T	C28(1.36)	LDD0892	[24]
LDCM0295	AC34	HEK-293T	C28(1.31)	LDD0893	[24]
LDCM0296	AC35	HEK-293T	C28(0.75)	LDD0894	[24]
LDCM0297	AC36	HEK-293T	C28(1.01)	LDD0895	[24]
LDCM0298	AC37	HEK-293T	C28(1.07)	LDD0896	[24]
LDCM0299	AC38	HEK-293T	C28(1.07)	LDD0897	[24]
LDCM0300	AC39	HEK-293T	C28(1.03)	LDD0898	[24]
LDCM0301	AC4	HCT 116	C28(2.03)	LDD0618	[24]
LDCM0302	AC40	HEK-293T	C28(1.12)	LDD0900	[24]
LDCM0303	AC41	HEK-293T	C28(1.15)	LDD0901	[24]
LDCM0304	AC42	HEK-293T	C28(1.26)	LDD0902	[24]
LDCM0305	AC43	HEK-293T	C28(1.33)	LDD0903	[24]
LDCM0306	AC44	HEK-293T	C28(1.34)	LDD0904	[24]
LDCM0307	AC45	HEK-293T	C28(1.10)	LDD0905	[24]
LDCM0308	AC46	HEK-293T	C28(0.86)	LDD0906	[24]
LDCM0309	AC47	HEK-293T	C28(0.98)	LDD0907	[24]
LDCM0310	AC48	HEK-293T	C28(0.95)	LDD0908	[24]
LDCM0311	AC49	HEK-293T	C28(1.08)	LDD0909	[24]
LDCM0312	AC5	HCT 116	C28(2.08)	LDD0629	[24]
LDCM0313	AC50	HEK-293T	C28(1.10)	LDD0911	[24]
LDCM0314	AC51	HEK-293T	C28(1.27)	LDD0912	[24]
LDCM0315	AC52	HEK-293T	C28(1.28)	LDD0913	[24]
LDCM0316	AC53	HEK-293T	C28(1.18)	LDD0914	[24]
LDCM0317	AC54	HEK-293T	C28(1.27)	LDD0915	[24]
LDCM0318	AC55	HEK-293T	C28(1.19)	LDD0916	[24]
LDCM0319	AC56	HEK-293T	C28(1.24)	LDD0917	[24]
LDCM0320	AC57	HCT 116	C28(1.60)	LDD0637	[24]
LDCM0321	AC58	HCT 116	C28(2.21)	LDD0638	[24]
LDCM0322	AC59	HCT 116	C28(1.78)	LDD0639	[24]
LDCM0323	AC6	HCT 116	C28(1.15)	LDD0640	[24]
LDCM0324	AC60	HCT 116	C28(1.87)	LDD0641	[24]
LDCM0325	AC61	HCT 116	C28(1.87)	LDD0642	[24]
LDCM0326	AC62	HCT 116	C28(1.70)	LDD0643	[24]
LDCM0327	AC63	HCT 116	C28(1.73)	LDD0644	[24]
LDCM0328	AC64	HCT 116	C28(1.94)	LDD0645	[24]
LDCM0329	AC65	HCT 116	C28(2.18)	LDD0646	[24]
LDCM0330	AC66	HCT 116	C28(2.07)	LDD0647	[24]
LDCM0331	AC67	HCT 116	C28(2.48)	LDD0648	[24]
LDCM0332	AC68	HCT 116	C28(1.24)	LDD0649	[24]
LDCM0333	AC69	HCT 116	C28(1.44)	LDD0650	[24]
LDCM0334	AC7	HCT 116	C28(1.22)	LDD0651	[24]
LDCM0335	AC70	HCT 116	C28(1.39)	LDD0652	[24]
LDCM0336	AC71	HCT 116	C28(1.24)	LDD0653	[24]
LDCM0337	AC72	HCT 116	C28(1.56)	LDD0654	[24]
LDCM0338	AC73	HCT 116	C28(2.11)	LDD0655	[24]
LDCM0339	AC74	HCT 116	C28(2.20)	LDD0656	[24]
LDCM0340	AC75	HCT 116	C28(2.46)	LDD0657	[24]
LDCM0341	AC76	HCT 116	C28(1.64)	LDD0658	[24]
LDCM0342	AC77	HCT 116	C28(1.43)	LDD0659	[24]
LDCM0343	AC78	HCT 116	C28(1.20)	LDD0660	[24]
LDCM0344	AC79	HCT 116	C28(1.34)	LDD0661	[24]
LDCM0345	AC8	HCT 116	C28(1.38)	LDD0662	[24]
LDCM0346	AC80	HCT 116	C28(1.32)	LDD0663	[24]
LDCM0347	AC81	HCT 116	C28(1.28)	LDD0664	[24]
LDCM0348	AC82	HCT 116	C28(2.26)	LDD0665	[24]
LDCM0349	AC83	HEK-293T	C28(1.01)	LDD0947	[24]
LDCM0350	AC84	HEK-293T	C28(1.28)	LDD0948	[24]
LDCM0351	AC85	HEK-293T	C28(1.22)	LDD0949	[24]
LDCM0352	AC86	HEK-293T	C28(1.30)	LDD0950	[24]
LDCM0353	AC87	HEK-293T	C28(1.27)	LDD0951	[24]
LDCM0354	AC88	HEK-293T	C28(1.28)	LDD0952	[24]
LDCM0355	AC89	HEK-293T	C28(1.48)	LDD0953	[24]
LDCM0357	AC90	HEK-293T	C28(1.46)	LDD0955	[24]
LDCM0358	AC91	HEK-293T	C28(1.13)	LDD0956	[24]
LDCM0359	AC92	HEK-293T	C28(1.18)	LDD0957	[24]
LDCM0360	AC93	HEK-293T	C28(1.28)	LDD0958	[24]
LDCM0361	AC94	HEK-293T	C28(1.31)	LDD0959	[24]
LDCM0362	AC95	HEK-293T	C28(1.23)	LDD0960	[24]
LDCM0363	AC96	HEK-293T	C28(1.28)	LDD0961	[24]
LDCM0364	AC97	HEK-293T	C28(2.29)	LDD0962	[24]
LDCM0365	AC98	HCT 116	C28(2.03)	LDD0682	[24]
LDCM0366	AC99	HCT 116	C28(0.90)	LDD0683	[24]
LDCM0248	AKOS034007472	HCT 116	C28(1.02)	LDD0565	[24]
LDCM0356	AKOS034007680	HCT 116	C28(1.05)	LDD0673	[24]
LDCM0275	AKOS034007705	HCT 116	C28(1.94)	LDD0592	[24]
LDCM0156	Aniline	NCI-H1299	12.59	LDD0403	[4]
LDCM0630	CCW28-3	231MFP	C28(1.63)	LDD2214	[25]
LDCM0108	Chloroacetamide	HeLa	N.A.	LDD0222	[20]
LDCM0367	CL1	HEK-293T	C28(2.68)	LDD0965	[24]
LDCM0368	CL10	HEK-293T	C28(3.28)	LDD0966	[24]
LDCM0369	CL100	HCT 116	C28(1.73)	LDD0686	[24]
LDCM0370	CL101	HCT 116	C28(1.33)	LDD0687	[24]
LDCM0371	CL102	HCT 116	C28(0.95)	LDD0688	[24]
LDCM0372	CL103	HCT 116	C28(1.07)	LDD0689	[24]
LDCM0373	CL104	HCT 116	C28(1.12)	LDD0690	[24]
LDCM0374	CL105	HCT 116	C28(1.58)	LDD0691	[24]
LDCM0375	CL106	HCT 116	C28(1.71)	LDD0692	[24]
LDCM0376	CL107	HCT 116	C28(1.24)	LDD0693	[24]
LDCM0377	CL108	HCT 116	C28(1.62)	LDD0694	[24]
LDCM0378	CL109	HCT 116	C28(1.78)	LDD0695	[24]
LDCM0379	CL11	HEK-293T	C28(3.05)	LDD0977	[24]
LDCM0380	CL110	HCT 116	C28(1.28)	LDD0697	[24]
LDCM0381	CL111	HCT 116	C28(1.74)	LDD0698	[24]
LDCM0382	CL112	HEK-293T	C28(2.29)	LDD0980	[24]
LDCM0383	CL113	HEK-293T	C28(1.27)	LDD0981	[24]
LDCM0384	CL114	HEK-293T	C28(2.90)	LDD0982	[24]
LDCM0385	CL115	HEK-293T	C28(2.08)	LDD0983	[24]
LDCM0386	CL116	HEK-293T	C28(1.72)	LDD0984	[24]
LDCM0387	CL117	HEK-293T	C28(1.84)	LDD0985	[24]
LDCM0388	CL118	HEK-293T	C28(1.05)	LDD0986	[24]
LDCM0389	CL119	HEK-293T	C28(1.24)	LDD0987	[24]
LDCM0390	CL12	HEK-293T	C28(1.31)	LDD0988	[24]
LDCM0391	CL120	HEK-293T	C28(1.42)	LDD0989	[24]
LDCM0392	CL121	HEK-293T	C28(1.21)	LDD0990	[24]
LDCM0393	CL122	HEK-293T	C28(1.24)	LDD0991	[24]
LDCM0394	CL123	HEK-293T	C28(1.65)	LDD0992	[24]
LDCM0395	CL124	HEK-293T	C28(1.22)	LDD0993	[24]
LDCM0396	CL125	HCT 116	C28(1.17)	LDD0713	[24]
LDCM0397	CL126	HCT 116	C28(1.10)	LDD0714	[24]
LDCM0398	CL127	HCT 116	C28(1.00)	LDD0715	[24]
LDCM0399	CL128	HCT 116	C28(1.70)	LDD0716	[24]
LDCM0400	CL13	HEK-293T	C28(1.49)	LDD0998	[24]
LDCM0401	CL14	HEK-293T	C28(2.24)	LDD0999	[24]
LDCM0402	CL15	HEK-293T	C28(4.25)	LDD1000	[24]
LDCM0403	CL16	HEK-293T	C28(1.25)	LDD1001	[24]
LDCM0404	CL17	HEK-293T	C28(1.94)	LDD1002	[24]
LDCM0405	CL18	HEK-293T	C28(1.41)	LDD1003	[24]
LDCM0406	CL19	HEK-293T	C28(1.25)	LDD1004	[24]
LDCM0407	CL2	HEK-293T	C28(2.42)	LDD1005	[24]
LDCM0408	CL20	HEK-293T	C28(1.22)	LDD1006	[24]
LDCM0409	CL21	HEK-293T	C28(4.69)	LDD1007	[24]
LDCM0410	CL22	HEK-293T	C28(1.50)	LDD1008	[24]
LDCM0411	CL23	HEK-293T	C28(0.93)	LDD1009	[24]
LDCM0412	CL24	HEK-293T	C28(1.20)	LDD1010	[24]
LDCM0413	CL25	HEK-293T	C28(1.92)	LDD1011	[24]
LDCM0414	CL26	HEK-293T	C28(1.12)	LDD1012	[24]
LDCM0415	CL27	HEK-293T	C28(1.55)	LDD1013	[24]
LDCM0416	CL28	HEK-293T	C28(1.49)	LDD1014	[24]
LDCM0417	CL29	HEK-293T	C28(1.07)	LDD1015	[24]
LDCM0418	CL3	HEK-293T	C28(1.31)	LDD1016	[24]
LDCM0419	CL30	HEK-293T	C28(1.38)	LDD1017	[24]
LDCM0420	CL31	HEK-293T	C28(1.84)	LDD1018	[24]
LDCM0421	CL32	HEK-293T	C28(1.55)	LDD1019	[24]
LDCM0422	CL33	HEK-293T	C28(2.82)	LDD1020	[24]
LDCM0423	CL34	HEK-293T	C28(1.51)	LDD1021	[24]
LDCM0424	CL35	HEK-293T	C28(1.53)	LDD1022	[24]
LDCM0425	CL36	HEK-293T	C28(1.37)	LDD1023	[24]
LDCM0426	CL37	HEK-293T	C28(1.54)	LDD1024	[24]
LDCM0428	CL39	HEK-293T	C28(3.77)	LDD1026	[24]
LDCM0429	CL4	HEK-293T	C28(1.55)	LDD1027	[24]
LDCM0430	CL40	HEK-293T	C28(1.36)	LDD1028	[24]
LDCM0431	CL41	HEK-293T	C28(2.53)	LDD1029	[24]
LDCM0432	CL42	HEK-293T	C28(2.06)	LDD1030	[24]
LDCM0433	CL43	HEK-293T	C28(2.13)	LDD1031	[24]
LDCM0434	CL44	HEK-293T	C28(1.38)	LDD1032	[24]
LDCM0435	CL45	HEK-293T	C28(3.20)	LDD1033	[24]
LDCM0436	CL46	HEK-293T	C28(1.94)	LDD1034	[24]
LDCM0437	CL47	HEK-293T	C28(1.29)	LDD1035	[24]
LDCM0438	CL48	HEK-293T	C28(1.19)	LDD1036	[24]
LDCM0439	CL49	HEK-293T	C28(1.48)	LDD1037	[24]
LDCM0440	CL5	HEK-293T	C28(1.79)	LDD1038	[24]
LDCM0441	CL50	HEK-293T	C28(1.92)	LDD1039	[24]
LDCM0442	CL51	HEK-293T	C28(1.76)	LDD1040	[24]
LDCM0443	CL52	HEK-293T	C28(0.98)	LDD1041	[24]
LDCM0444	CL53	HEK-293T	C28(1.05)	LDD1042	[24]
LDCM0445	CL54	HEK-293T	C28(1.57)	LDD1043	[24]
LDCM0446	CL55	HEK-293T	C28(1.42)	LDD1044	[24]
LDCM0447	CL56	HEK-293T	C28(1.31)	LDD1045	[24]
LDCM0448	CL57	HEK-293T	C28(1.90)	LDD1046	[24]
LDCM0449	CL58	HEK-293T	C28(0.98)	LDD1047	[24]
LDCM0450	CL59	HEK-293T	C28(1.47)	LDD1048	[24]
LDCM0451	CL6	HEK-293T	C28(1.83)	LDD1049	[24]
LDCM0452	CL60	HEK-293T	C28(2.18)	LDD1050	[24]
LDCM0453	CL61	HEK-293T	C28(1.54)	LDD1051	[24]
LDCM0454	CL62	HEK-293T	C28(2.05)	LDD1052	[24]
LDCM0455	CL63	HEK-293T	C28(2.05)	LDD1053	[24]
LDCM0456	CL64	HEK-293T	C28(2.46)	LDD1054	[24]
LDCM0457	CL65	HEK-293T	C28(1.36)	LDD1055	[24]
LDCM0458	CL66	HEK-293T	C28(1.66)	LDD1056	[24]
LDCM0459	CL67	HEK-293T	C28(1.27)	LDD1057	[24]
LDCM0460	CL68	HEK-293T	C28(1.51)	LDD1058	[24]
LDCM0461	CL69	HEK-293T	C28(1.44)	LDD1059	[24]
LDCM0462	CL7	HEK-293T	C28(1.86)	LDD1060	[24]
LDCM0463	CL70	HEK-293T	C28(1.13)	LDD1061	[24]
LDCM0464	CL71	HEK-293T	C28(1.48)	LDD1062	[24]
LDCM0465	CL72	HEK-293T	C28(1.17)	LDD1063	[24]
LDCM0466	CL73	HEK-293T	C28(1.90)	LDD1064	[24]
LDCM0467	CL74	HEK-293T	C28(2.64)	LDD1065	[24]
LDCM0469	CL76	HEK-293T	C28(1.17)	LDD1067	[24]
LDCM0470	CL77	HEK-293T	C28(1.99)	LDD1068	[24]
LDCM0471	CL78	HEK-293T	C28(1.56)	LDD1069	[24]
LDCM0472	CL79	HEK-293T	C28(1.54)	LDD1070	[24]
LDCM0473	CL8	HEK-293T	C28(2.42)	LDD1071	[24]
LDCM0474	CL80	HEK-293T	C28(1.24)	LDD1072	[24]
LDCM0475	CL81	HEK-293T	C28(1.22)	LDD1073	[24]
LDCM0476	CL82	HEK-293T	C28(0.97)	LDD1074	[24]
LDCM0477	CL83	HEK-293T	C28(1.36)	LDD1075	[24]
LDCM0478	CL84	HEK-293T	C28(2.04)	LDD1076	[24]
LDCM0479	CL85	HEK-293T	C28(1.46)	LDD1077	[24]
LDCM0480	CL86	HEK-293T	C28(1.75)	LDD1078	[24]
LDCM0481	CL87	HEK-293T	C28(1.96)	LDD1079	[24]
LDCM0482	CL88	HEK-293T	C28(1.35)	LDD1080	[24]
LDCM0483	CL89	HEK-293T	C28(1.54)	LDD1081	[24]
LDCM0484	CL9	HEK-293T	C28(2.16)	LDD1082	[24]
LDCM0485	CL90	HEK-293T	C28(2.57)	LDD1083	[24]
LDCM0486	CL91	HCT 116	C28(1.23)	LDD0803	[24]
LDCM0487	CL92	HCT 116	C28(1.37)	LDD0804	[24]
LDCM0488	CL93	HCT 116	C28(1.40)	LDD0805	[24]
LDCM0489	CL94	HCT 116	C28(1.73)	LDD0806	[24]
LDCM0490	CL95	HCT 116	C28(1.97)	LDD0807	[24]
LDCM0491	CL96	HCT 116	C28(1.44)	LDD0808	[24]
LDCM0492	CL97	HCT 116	C28(1.29)	LDD0809	[24]
LDCM0493	CL98	HCT 116	C28(2.12)	LDD0810	[24]
LDCM0494	CL99	HCT 116	C28(1.66)	LDD0811	[24]
LDCM0033	Curcusone1d	MCF-7	2.20	LDD0188	[5]
LDCM0175	Ethacrynic acid	HeLa	C28(1.06)	LDD2210	[10]
LDCM0202	EV-93	T cell	C28(5.00)	LDD0514	[26]
LDCM0625	F8	Ramos	C28(1.78); 1.84	LDD2187	[27]
LDCM0573	Fragment11	Ramos	C28(9.38); 12.57	LDD2190	[27]
LDCM0575	Fragment13	Ramos	C28(1.09)	LDD2192	[27]
LDCM0576	Fragment14	Ramos	C28(16.98)	LDD2193	[27]
LDCM0580	Fragment21	Ramos	C28(1.10)	LDD2195	[27]
LDCM0582	Fragment23	Ramos	C28(0.98)	LDD2196	[27]
LDCM0578	Fragment27	Ramos	C28(0.84)	LDD2197	[27]
LDCM0586	Fragment28	Ramos	C28(1.08); 2.62	LDD2198	[27]
LDCM0588	Fragment30	Ramos	C28(1.61)	LDD2199	[27]
LDCM0589	Fragment31	Ramos	C28(1.51)	LDD2200	[27]
LDCM0468	Fragment33	HEK-293T	C28(2.65)	LDD1066	[24]
LDCM0596	Fragment38	Ramos	C28(1.83)	LDD2203	[27]
LDCM0566	Fragment4	Ramos	C28(6.51)	LDD2184	[27]
LDCM0427	Fragment51	HEK-293T	C28(1.73)	LDD1025	[24]
LDCM0610	Fragment52	Ramos	C28(2.16)	LDD2204	[27]
LDCM0614	Fragment56	Ramos	C28(1.31)	LDD2205	[27]
LDCM0616	Fragment61	Jurkat	_(4.08)	LDD1489	[6]
LDCM0617	Fragment63-S	Jurkat	_(5.47)	LDD1490	[6]
LDCM0569	Fragment7	Ramos	C28(8.15)	LDD2186	[27]
LDCM0107	IAA	HeLa	N.A.	LDD0221	[20]
LDCM0022	KB02	T cell	C28(7.29)	LDD1703	[26]
LDCM0023	KB03	Jurkat	C28(62.78)	LDD0209	[11]
LDCM0024	KB05	NCI-H1792	C28(2.60)	LDD3348	[28]
LDCM0169	KB63	Ramos	5.21	LDD0432	[29]
LDCM0628	OTUB2-COV-1	HEK-293T	C28(0.73)	LDD2207	[30]
LDCM0014	Panhematin	HEK-293T	3.67	LDD0062	[8]
LDCM0131	RA190	MM1.R	12.91	LDD0299	[9]

Protein name				Family	Uniprot ID
Phosphatidylserine lipase ABHD16A (ABHD16A)				ABHD16 family	O95870
Anterior gradient protein 3 (AGR3)				AGR family	Q8TD06
Palmitoyltransferase ZDHHC15 (ZDHHC15)				DHHC palmitoyltransferase family	Q96MV8
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH)				HIBADH-related family	P31937
E3 ubiquitin-protein ligase RNF5 (RNF5)				RNF5 family	Q99942
Estradiol 17-beta-dehydrogenase 11 (HSD17B11)				Short-chain dehydrogenases/reductases (SDR) family	Q8NBQ5
TLC domain-containing protein 4 (TLCD4)				TLCD4 family	Q96MV1

Protein name				Family	Uniprot ID
Sodium-dependent organic anion transporter (SLC10A6)				Bile acid:sodium symporter (BASS) family	Q3KNW5
Gap junction alpha-5 protein (GJA5)				Connexin family	P36382
Gap junction alpha-8 protein (GJA8)				Connexin family	P48165
Aquaporin-6 (AQP6)				MIP/aquaporin (TC 1.A.8) family	Q13520
Transmembrane protein 14B (TMEM14B)				TMEM14 family	Q9NUH8
Thioredoxin-related transmembrane protein 2 (TMX2)				.	Q9Y320

Protein name				Family	Uniprot ID
Probable G-protein coupled receptor 152 (GPR152)				G-protein coupled receptor 1 family	Q8TDT2
Adhesion G-protein coupled receptor D1 (ADGRD1)				G-protein coupled receptor 2 family	Q6QNK2

Protein name				Family	Uniprot ID
B-cell antigen receptor complex-associated protein alpha chain (CD79A)				.	P11912

Protein name				Family	Uniprot ID
Receptor expression-enhancing protein 4 (REEP4)				DP1 family	Q9H6H4
Cytosolic iron-sulfur assembly component 2A (CIAO2A)				MIP18 family	Q9H5X1
Reticulophagy regulator 3 (RETREG3)				RETREG family	Q86VR2
Mitochondrial dynamics protein MIEF1 (MIEF1)				SMCR7 family	Q9NQG6
C-type lectin domain family 10 member A (CLEC10A)				.	Q8IUN9
Mast cell-expressed membrane protein 1 (MCEMP1)				.	Q8IX19
Receptor-binding cancer antigen expressed on SiSo cells (EBAG9)				.	O00559

1	Fatty Acyl Sulfonyl Fluoride as an Activity-Based Probe for Profiling Fatty Acid-Associated Proteins in Living Cells. Chembiochem. 2022 Feb 16;23(4):e202100628. doi: 10.1002/cbic.202100628. Epub 2021 Dec 30.
2	Charting the Chemical Space of Acrylamide-Based Inhibitors of zDHHC20. ACS Med Chem Lett. 2022 Sep 26;13(10):1648-1654. doi: 10.1021/acsmedchemlett.2c00336. eCollection 2022 Oct 13.
3	Tranylcypromine specificity for monoamine oxidase is limited by promiscuous protein labelling and lysosomal trapping. RSC Chem Biol. 2020 Aug 12;1(4):209-213. doi: 10.1039/d0cb00048e. eCollection 2020 Oct 1. Mass spectrometry data entry: PXD018580
4	Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
5	Total Synthesis and Target Identification of the Curcusone Diterpenes. J Am Chem Soc. 2021 Mar 24;143(11):4379-4386. doi: 10.1021/jacs.1c00557. Epub 2021 Mar 11.
6	Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.
7	Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z. Mass spectrometry data entry: PXD044625
8	A Chemical Proteomic Map of Heme-Protein Interactions. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12. Mass spectrometry data entry: PXD034651
9	Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.
10	Chemoproteomic Profiling Reveals Ethacrynic Acid Targets Adenine Nucleotide Translocases to Impair Mitochondrial Function. Mol Pharm. 2018 Jun 4;15(6):2413-2422. doi: 10.1021/acs.molpharmaceut.8b00250. Epub 2018 May 15.
11	Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.
12	Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23. Mass spectrometry data entry: PXD028853
13	SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18. Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
14	Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24. Mass spectrometry data entry: PXD029255
15	N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w. Mass spectrometry data entry: PXD041264
16	A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21. Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
17	A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16. Mass spectrometry data entry: PXD043348
18	Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20. Mass spectrometry data entry: PXD022279
19	DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22. Mass spectrometry data entry: PXD033004
20	ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
21	Quantitative Proteomics Reveals Cellular Off-Targets of a DDR1 Inhibitor. ACS Med Chem Lett. 2020 Feb 5;11(4):535-540. doi: 10.1021/acsmedchemlett.9b00658. eCollection 2020 Apr 9.
22	Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26. Mass spectrometry data entry: PXD041587
23	Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20. Mass spectrometry data entry: PXD007570
24	Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
25	Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
26	An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.
27	Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7. Mass spectrometry data entry: PXD027578
28	DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22. Mass spectrometry data entry: PXD047840
29	2-Sulfonylpyridines as Tunable, Cysteine-Reactive Electrophiles. J Am Chem Soc. 2020 May 13;142(19):8972-8979. doi: 10.1021/jacs.0c02721. Epub 2020 Apr 29.
30	Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.