Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C350  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 181 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 99.7
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 99.7
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 99.7
 LDTP00697  Cytochrome b5 type B (CYB5B) 99.7
 LDTP02359  Heme oxygenase 1 (HMOX1) 99.7
 LDTP03540  Heme oxygenase 2 (HMOX2) 99.7
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 99.7
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 99.7
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 99.7
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 99.7
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 99.7
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 99.7
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 99.7
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 98.4
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 96.3
 LDTP01743  NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) 86.2
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 82.1
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 82.1
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2) 81.0
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 74.0
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 73.0
 LDTP09874  Endoplasmic reticulum protein SC65 (P3H4) 72.5
 LDTP05905  Acid ceramidase (ASAH1) 69.1
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 68.6
 LDTP05409  Antigen peptide transporter 2 (TAP2) 67.6
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 67.6
 LDTP06142  Squalene monooxygenase (SQLE) 66.3
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 65.8
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 65.8
 LDTP09256  Putative phospholipase B-like 2 (PLBD2) 65.8
 LDTP07868  Protein O-mannosyl-transferase TMTC3 (TMTC3) 65.3
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 62.7
 LDTP10329  Ceramide synthase 2 (CERS2) 61.8
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 61.4
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 61.0
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 60.1
 LDTP04634  Alpha-N-acetylglucosaminidase (NAGLU) 58.9
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 57.7
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 56.9
 LDTP02000  3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) 56.5
 LDTP04358  Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) 56.5
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1) 56.5
 LDTP09088  Phospholipase A2 group XV (PLA2G15) 55.7
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 54.6
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 53.4
 LDTP09799  DCN1-like protein 4 (DCUN1D4) 52.7
 LDTP13409  Anaphase-promoting complex subunit 7 (ANAPC7) 50.9
 LDTP08859  Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) 50.9
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 49.5
 LDTP00032  2-hydroxyacyl-CoA lyase 2 (ILVBL) 48.8
 LDTP06977  GPI ethanolamine phosphate transferase 2 (PIGG) 48.5
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 48.5
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 46.9
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 45.6
 LDTP11852  Presenilin-associated rhomboid-like protein, mitochondrial (PARL) 45.6
 LDTP03842  Squalene synthase (FDFT1) 45.3
 LDTP00783  Beta-1,4-glucuronyltransferase 1 (B4GAT1) 43.7
 LDTP11319  Threonine--tRNA ligase, mitochondrial (TARS2) 43.4
 LDTP04114  E3 ubiquitin-protein ligase NEDD4 (NEDD4) 43.1
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 42.8
 LDTP09251  Atlastin-2 (ATL2) 42.2
 LDTP07931  Heme A synthase COX15 (COX15) 41.9
 LDTP03145  Catechol O-methyltransferase (COMT) 41.6
 LDTP14030  V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) 41.6
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 41.4
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 41.4
 LDTP09188  Lysophosphatidylcholine acyltransferase 1 (LPCAT1) 41.1
 LDTP12639  1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) 40.5
 LDTP19851  Isochorismatase domain-containing protein 1 (ISOC1) 40.5
 LDTP08378  Serine/threonine-protein kinase VRK2 (VRK2) 40.2
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 40.2
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 39.7
 LDTP09396  Minor histocompatibility antigen H13 (HM13) 39.7
 LDTP01329  Lathosterol oxidase (SC5D) 39.4
 LDTP00950  Dynamin-like 120 kDa protein, mitochondrial (OPA1) 38.1
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 37.8
 LDTP08203  E3 ubiquitin-protein ligase synoviolin (SYVN1) 37.5
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) 37.3
 LDTP15988  Probable serine carboxypeptidase CPVL (CPVL) 37.3
 LDTP02486  Lysosomal alpha-glucosidase (GAA) 37.0
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 36.8
 LDTP10550  Dehydrogenase/reductase SDR family member 1 (DHRS1) 36.5
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 36.3
 LDTP06370  Ephrin type-A receptor 7 (EPHA7) 36.3
 LDTP12420  Xaa-Pro aminopeptidase 3 (XPNPEP3) 36.3
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 36.0
 LDTP10471  Protein disulfide-isomerase TMX3 (TMX3) 36.0
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 35.8
 LDTP02505  Lysosomal protective protein (CTSA) 35.8
 LDTP12720  Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) 35.8
 LDTP03680  DNA replication licensing factor MCM4 (MCM4) 35.3
 LDTP01300  Cartilage-associated protein (CRTAP) 34.8
 LDTP04581  Holocytochrome c-type synthase (HCCS) 34.5
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 34.1
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 33.4
 LDTP19838  Immunity-related GTPase family Q protein (IRGQ) 33.1
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 33.1
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 32.9
 LDTP02141  Alpha-galactosidase A (GLA) 32.7
 LDTP02837  Beta-galactosidase (GLB1) 32.7
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 32.4
 LDTP08799  Lysophosphatidylserine lipase ABHD12 (ABHD12) 31.8
 LDTP05396  Histone-lysine N-methyltransferase 2A (KMT2A) 31.3
 LDTP00988  Protein O-GlcNAcase (OGA) 31.3
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 31.1
 LDTP09814  Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) 30.7
 LDTP11199  DCN1-like protein 5 (DCUN1D5) 30.7
 LDTP02539  Lysosomal acid phosphatase (ACP2) 30.7
 LDTP10020  Ras-related protein Rab-24 (RAB24) 30.5
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 30.3
 LDTP04440  Peroxisomal multifunctional enzyme type 2 (HSD17B4) 30.1
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) 30.1
 LDTP10249  Metalloendopeptidase OMA1, mitochondrial (OMA1) 29.4
 LDTP11273  N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) 29.4
 LDTP14427  Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L) 29.2
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 29.2
 LDTP03198  Ferrochelatase, mitochondrial (FECH) 29.2
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 29.2
 LDTP04569  Geranylgeranyl transferase type-2 subunit beta (RABGGTB) 28.8
 LDTP10966  Microsomal glutathione S-transferase 2 (MGST2) 28.6
 LDTP05850  Probable methyltransferase TARBP1 (TARBP1) 28.4
 LDTP10137  Cytochrome c oxidase assembly factor 7 (COA7) 28.1
 LDTP12227  Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) 28.1
 LDTP04531  Hexokinase-2 (HK2) 27.9
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 27.9
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 27.7
 LDTP07154  ATPase family AAA domain-containing protein 3B (ATAD3B) 27.5
 LDTP15484  Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) 27.1
 LDTP13408  Cell division cycle protein 23 homolog (CDC23) 26.9
 LDTP02721  Farnesyl pyrophosphate synthase (FDPS) 26.9
 LDTP13486  Long-chain-fatty-acid--CoA ligase 6 (ACSL6) 26.9
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 26.9
 LDTP04925  Pterin-4-alpha-carbinolamine dehydratase (PCBD1) 26.7
 LDTP10699  E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) 26.5
 LDTP10930  Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) 26.5
 LDTP11437  Peroxisomal trans-2-enoyl-CoA reductase (PECR) 26.5
 LDTP01335  Protein SCO1 homolog, mitochondrial (SCO1) 26.5
 LDTP13358  Leucyl-cystinyl aminopeptidase (LNPEP) 26.4
 LDTP04962  26S proteasome regulatory subunit 4 (PSMC1) 26.2
 LDTP01065  E3 ubiquitin-protein ligase TRIM13 (TRIM13) 26.2
 LDTP03769  Sterol O-acyltransferase 1 (SOAT1) 26.2
 LDTP12752  NADH dehydrogenase 1 beta subcomplex subunit 11, mitochondrial (NDUFB11) 26.0
 LDTP07003  Presequence protease, mitochondrial (PITRM1) 26.0
 LDTP02169  Beta-hexosaminidase subunit alpha (HEXA) 25.8
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 25.8
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 25.5
 LDTP00836  ATPase GET3 (GET3) 25.5
 LDTP04203  Phosphatidylserine synthase 1 (PTDSS1) 25.5
 LDTP03249  Plasma membrane calcium-transporting ATPase 4 (ATP2B4) 25.5
 LDTP01704  Phosphatidylserine lipase ABHD16A (ABHD16A) 25.1
 LDTP00186  Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) 24.8
 LDTP03060  Proteasome subunit beta type-1 (PSMB1) 24.8
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 24.6
 LDTP09063  Estradiol 17-beta-dehydrogenase 11 (HSD17B11) 24.4
 LDTP06315  Platelet-activating factor acetylhydrolase IB subunit alpha1 (PAFAH1B3) 24.4
 LDTP01047  Dolichol-phosphate mannosyltransferase subunit 1 (DPM1) 23.9
 LDTP09835  GPI-anchor transamidase (PIGK) 23.9
 LDTP00344  Stearoyl-CoA desaturase (SCD) 23.9
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 23.8
 LDTP15097  All-trans-retinol 13,14-reductase (RETSAT) 23.8
 LDTP03779  Copper-transporting ATPase 2 (ATP7B) 23.8
 LDTP04895  Ras-related protein Rab-10 (RAB10) 23.8
 LDTP07227  Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) 23.8
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 23.6
 LDTP09388  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (STT3B) 23.6
 LDTP00907  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) 23.1
 LDTP03394  Ceramide synthase 1 (CERS1) 22.9
 LDTP02385  Leukotriene A-4 hydrolase (LTA4H) 22.8
 LDTP00877  Protein SCO2 homolog, mitochondrial (SCO2) 22.8
 LDTP11035  Dihydropyrimidinase-related protein 5 (DPYSL5) 22.6
 LDTP12608  Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) 22.6
 LDTP09495  Probable glutathione peroxidase 8 (GPX8) 22.6
 LDTP00597  Serine palmitoyltransferase 1 (SPTLC1) 22.6
 LDTP05733  Serine/threonine-protein kinase 4 (STK4) 22.5
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) 22.3
 LDTP13814  Phospholipase A-2-activating protein (PLAA) 22.3
 LDTP12470  GTP-binding protein SAR1a (SAR1A) 22.2
 LDTP03418  Proteasome subunit beta type-6 (PSMB6) 22.2
 LDTP04247  Protein farnesyltransferase subunit beta (FNTB) 22.2
 LDTP01699  Acyl-CoA 6-desaturase (FADS2) 22.0
 LDTP00536  Mitochondrial ribonuclease P catalytic subunit (PRORP) 22.0
Transporter and channel
Click to Show/Hide to Show 149 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01804  ATP synthase subunit a (MT-ATP6) 99.7
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 99.7
 LDTP11245  Derlin-1 (DERL1) 99.7
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 99.7
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 99.7
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 99.7
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 99.7
 LDTP14099  Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) 99.7
 LDTP11615  Protein tweety homolog 3 (TTYH3) 99.7
 LDTP12207  Putative divalent cation/proton antiporter TMEM165 (TMEM165) 99.7
 LDTP06633  Reticulon-1 (RTN1) 99.7
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 99.7
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 99.7
 LDTP16813  Tetraspanin-3 (TSPAN3) 99.7
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 99.7
 LDTP15948  Transmembrane protein 126A (TMEM126A) 99.7
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 99.7
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 99.7
 LDTP11250  MICOS complex subunit MIC26 (APOO) 96.3
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 96.3
 LDTP00857  Syntaxin-6 (STX6) 95.0
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 93.7
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 91.1
 LDTP15481  Transmembrane protein 87A (TMEM87A) 89.9
 LDTP10065  Transmembrane protein 230 (TMEM230) 85.0
 LDTP07531  Sideroflexin-4 (SFXN4) 83.3
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 77.7
 LDTP00547  Secretory carrier-associated membrane protein 2 (SCAMP2) 77.2
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 74.5
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 74.0
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 73.5
 LDTP08469  Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) 67.6
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 67.2
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 66.7
 LDTP08881  Transmembrane protein 199 (TMEM199) 66.7
 LDTP06365  Transmembrane emp24 domain-containing protein 2 (TMED2) 65.3
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 64.0
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 62.7
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 61.4
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 60.1
 LDTP04227  Guided entry of tail-anchored proteins factor CAMLG (CAMLG) 59.3
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 59.3
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 57.3
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 56.9
 LDTP02215  Prosaposin (PSAP) 56.1
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 55.7
 LDTP06221  StAR-related lipid transfer protein 3 (STARD3) 52.3
 LDTP09294  Proton-coupled zinc antiporter SLC30A5 (SLC30A5) 49.5
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 48.2
 LDTP07236  Protein GPR107 (GPR107) 48.2
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 47.2
 LDTP06499  V-type proton ATPase subunit S1 (ATP6AP1) 46.9
 LDTP05900  Metaxin-1 (MTX1) 45.9
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 45.9
 LDTP12451  Integral membrane protein 2C (ITM2C) 45.3
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 44.9
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 44.3
 LDTP00541  NPC intracellular cholesterol transporter 1 (NPC1) 43.7
 LDTP12704  Anoctamin-10 (ANO10) 42.8
 LDTP14200  Mitochondrial ornithine transporter 1 (SLC25A15) 42.5
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 41.9
 LDTP18459  StAR-related lipid transfer protein 7, mitochondrial (STARD7) 41.4
 LDTP13262  Signal recognition particle subunit SRP68 (SRP68) 41.1
 LDTP10343  Vacuole membrane protein 1 (VMP1) 40.5
 LDTP01060  PRA1 family protein 2 (PRAF2) 40.2
 LDTP10731  Sodium-coupled neutral amino acid symporter 2 (SLC38A2) 39.7
 LDTP14717  ATP synthase subunit e, mitochondrial (ATP5ME) 38.6
 LDTP03559  High affinity cationic amino acid transporter 1 (SLC7A1) 38.6
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 38.6
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 38.6
 LDTP13969  Transmembrane emp24 domain-containing protein 7 (TMED7) 38.1
 LDTP02087  ADP/ATP translocase 2 (SLC25A5) 37.5
 LDTP11095  Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) 37.5
 LDTP10073  Protein RFT1 homolog (RFT1) 37.5
 LDTP15979  Transmembrane protein 245 (TMEM245) 37.5
 LDTP01217  Metaxin-2 (MTX2) 37.3
 LDTP12809  Solute carrier family 2, facilitated glucose transporter member 8 (SLC2A8) 36.8
 LDTP12661  Exocyst complex component 1 (EXOC1) 36.3
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 36.3
 LDTP02608  ADP/ATP translocase 1 (SLC25A4) 35.5
 LDTP03380  Stomatin (STOM) 35.3
 LDTP10663  Importin-9 (IPO9) 35.0
 LDTP11281  Voltage-gated monoatomic cation channel TMEM109 (TMEM109) 35.0
 LDTP07477  Transmembrane protein 214 (TMEM214) 34.8
 LDTP10533  Sorting nexin-27 (SNX27) 34.3
 LDTP06660  MICOS complex subunit MIC60 (IMMT) 34.1
 LDTP04787  Transmembrane protein 33 (TMEM33) 34.1
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) 33.8
 LDTP01454  SUN domain-containing protein 1 (SUN1) 33.6
 LDTP03546  Translocator protein (TSPO) 33.1
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 32.9
 LDTP07064  Nucleoporin NUP188 (NUP188) 32.4
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 31.8
 LDTP00590  Protein RER1 (RER1) 31.6
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 31.1
 LDTP06945  Sigma intracellular receptor 2 (TMEM97) 30.9
 LDTP02562  Lysosome-associated membrane glycoprotein 1 (LAMP1) 30.7
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 30.1
 LDTP14084  Sorting and assembly machinery component 50 homolog (SAMM50) 30.1
 LDTP10804  Chloride channel CLIC-like protein 1 (CLCC1) 29.9
 LDTP11291  Transmembrane emp24 domain-containing protein 9 (TMED9) 29.9
 LDTP00405  Etoposide-induced protein 2.4 homolog (EI24) 29.7
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 29.7
 LDTP15845  Transmembrane 9 superfamily member 2 (TM9SF2) 29.7
 LDTP03405  Calnexin (CANX) 29.4
 LDTP07462  MFS-type transporter SLC18B1 (SLC18B1) 29.4
 LDTP13943  Thioredoxin-related transmembrane protein 2 (TMX2) 29.2
 LDTP09288  Vang-like protein 1 (VANGL1) 28.6
 LDTP01200  Peroxisomal membrane protein PEX14 (PEX14) 28.2
 LDTP11213  Nucleoporin NDC1 (NDC1) 27.9
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 27.7
 LDTP07058  Transmembrane protein 201 (TMEM201) 27.5
 LDTP01601  Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) 26.4
 LDTP00970  Gasdermin-E (GSDME) 26.2
 LDTP04459  H(+)/Cl(-) exchange transporter 3 (CLCN3) 26.0
 LDTP04501  Importin subunit alpha-1 (KPNA2) 26.0
 LDTP04237  Protein ERGIC-53 (LMAN1) 26.0
 LDTP04426  B-cell receptor-associated protein 31 (BCAP31) 25.8
 LDTP07537  Metal transporter CNNM4 (CNNM4) 25.8
 LDTP05780  Syntaxin-5 (STX5) 25.8
 LDTP13320  Prenylated Rab acceptor protein 1 (RABAC1) 25.6
 LDTP07583  Transmembrane protein 65 (TMEM65) 25.5
 LDTP11229  Transmembrane protein 70, mitochondrial (TMEM70) 25.3
 LDTP06293  Metal cation symporter ZIP14 (SLC39A14) 24.9
 LDTP09987  Secretory carrier-associated membrane protein 4 (SCAMP4) 24.6
 LDTP00821  Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) 24.4
 LDTP07152  Acyl-CoA-binding domain-containing protein 5 (ACBD5) 24.3
 LDTP06855  Anoctamin-6 (ANO6) 24.3
 LDTP09333  Golgin subfamily A member 5 (GOLGA5) 24.3
 LDTP10621  Sideroflexin-2 (SFXN2) 24.3
 LDTP01301  Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (SLC25A12) 24.1
 LDTP09028  Mitoguardin 1 (MIGA1) 23.9
 LDTP12090  Sideroflexin-1 (SFXN1) 23.9
 LDTP02068  Sodium/potassium-transporting ATPase subunit beta-1 (ATP1B1) 23.6
 LDTP15838  Translocation protein SEC62 (SEC62) 23.6
 LDTP01100  Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) 23.4
 LDTP01352  PRA1 family protein 3 (ARL6IP5) 23.4
 LDTP07667  Transmembrane protein 205 (TMEM205) 23.4
 LDTP09144  Metal transporter CNNM3 (CNNM3) 23.3
 LDTP06271  ER membrane protein complex subunit 2 (EMC2) 22.9
 LDTP09515  Importin-4 (IPO4) 22.8
 LDTP08769  Nuclear pore complex protein Nup93 (NUP93) 22.8
 LDTP13599  Calcium load-activated calcium channel (TMCO1) 22.6
 LDTP12078  Mitochondrial glutamate carrier 1 (SLC25A22) 22.6
 LDTP10885  Sortilin (SORT1) 22.6
 LDTP13953  Endophilin-B1 (SH3GLB1) 22.5
 LDTP06549  Hsp90 co-chaperone Cdc37 (CDC37) 22.2
 LDTP04956  Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) 22.0
 LDTP01380  Wolframin (WFS1) 22.0
Transcription factor
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 47.2
 LDTP09694  Paraspeckle component 1 (PSPC1) 41.4
Immunoglobulin
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03772  Basigin (BSG) 57.3
 LDTP05572  Leukocyte surface antigen CD47 (CD47) 52.3
 LDTP04720  IgG receptor FcRn large subunit p51 (FCGRT) 44.9
 LDTP02040  HLA class I histocompatibility antigen, A alpha chain (HLA-A) 25.8
Other
Click to Show/Hide to Show 151 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11076  Apolipoprotein L2 (APOL2) 99.7
 LDTP12642  CYFIP-related Rac1 interactor B (CYRIB) 99.7
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 99.7
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 99.7
 LDTP00850  ER lumen protein-retaining receptor 3 (KDELR3) 99.7
 LDTP00871  Microtubule nucleation factor SSNA1 (SSNA1) 99.7
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 99.7
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 99.7
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 99.7
 LDTP05160  Nucleobindin-2 (NUCB2) 99.7
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 99.7
 LDTP10056  Protein FAM162A (FAM162A) 99.7
 LDTP12287  Ran guanine nucleotide release factor (RANGRF) 99.7
 LDTP01167  Reticulon-2 (RTN2) 99.7
 LDTP12412  Reticulon-4 (RTN4) 99.7
 LDTP00986  Syntaxin-10 (STX10) 99.7
 LDTP14458  Tetraspanin-6 (TSPAN6) 99.7
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 99.7
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 94.4
 LDTP13086  Syntaxin-18 (STX18) 89.9
 LDTP01522  Reticulon-3 (RTN3) 88.0
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 84.4
 LDTP08606  Nurim (NRM) 80.4
 LDTP15269  Large ribosomal subunit protein mL55 (MRPL55) 77.2
 LDTP01163  Ubiquinone biosynthesis protein COQ9, mitochondrial (COQ9) 77.2
 LDTP04652  Eukaryotic translation initiation factor 5 (EIF5) 70.5
 LDTP06097  Reticulocalbin-2 (RCN2) 70.5
 LDTP02927  Ganglioside GM2 activator (GM2A) 70.0
 LDTP19963  TraB domain-containing protein (TRABD) 69.1
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 67.6
 LDTP18272  Transmembrane protein 209 (TMEM209) 66.7
 LDTP09773  Protein FAM3C (FAM3C) 66.3
 LDTP08224  Protein LYRIC (MTDH) 65.8
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 57.7
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 56.9
 LDTP15398  Protein FAM177A1 (FAM177A1) 55.7
 LDTP01494  Protein YIF1A (YIF1A) 53.8
 LDTP14126  Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) 51.6
 LDTP06291  ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) 50.6
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 49.2
 LDTP03729  General transcription factor IIF subunit 1 (GTF2F1) 48.5
 LDTP16080  Protein FAM114A2 (FAM114A2) 48.5
 LDTP07891  Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) 48.2
 LDTP12025  UPF0488 protein C8orf33 (C8orf33) 47.8
 LDTP00859  Synaptogyrin-2 (SYNGR2) 46.9
 LDTP18132  Protein FAM136A (FAM136A) 45.9
 LDTP12468  Diablo IAP-binding mitochondrial protein (DIABLO) 45.6
 LDTP11167  Protein YIPF4 (YIPF4) 45.3
 LDTP16322  Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) 44.9
 LDTP05375  Nucleobindin-1 (NUCB1) 44.0
 LDTP00632  Syntaxin-7 (STX7) 44.0
 LDTP15793  Protein FAM210A (FAM210A) 42.5
 LDTP08594  Negative elongation factor C/D (NELFCD) 42.2
 LDTP00417  Programmed cell death protein 5 (PDCD5) 41.6
 LDTP12729  Required for meiotic nuclear division protein 1 homolog (RMND1) 41.6
 LDTP17003  Matrix-remodeling-associated protein 7 (MXRA7) 41.4
 LDTP11906  Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) 41.1
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 41.1
 LDTP06892  Protein Hikeshi (HIKESHI) 39.9
 LDTP15253  HEAT repeat-containing protein 3 (HEATR3) 39.1
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 39.1
 LDTP01171  Zinc finger protein ZPR1 (ZPR1) 38.3
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 38.1
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 37.5
 LDTP00913  Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) 37.5
 LDTP04356  Emerin (EMD) 37.3
 LDTP10914  Translin-associated protein X (TSNAX) 37.3
 LDTP01359  Dynactin subunit 3 (DCTN3) 37.0
 LDTP09787  Nicastrin (NCSTN) 37.0
 LDTP10775  Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) 35.3
 LDTP10908  Protein S100-A13 (S100A13) 35.3
 LDTP00199  HCLS1-associated protein X-1 (HAX1) 35.0
 LDTP13125  Protein UXT (UXT) 34.5
 LDTP12379  Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) 34.3
 LDTP07192  Intermembrane lipid transfer protein VPS13D (VPS13D) 34.3
 LDTP08154  Large ribosomal subunit protein uL10m (MRPL10) 33.6
 LDTP15887  Lipase maturation factor 2 (LMF2) 32.9
 LDTP05715  Vesicle transport protein SEC20 (BNIP1) 32.7
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) 32.4
 LDTP02345  Retinol-binding protein 1 (RBP1) 32.4
 LDTP07368  Tetratricopeptide repeat protein 19, mitochondrial (TTC19) 32.4
 LDTP07718  MICOS complex subunit MIC27 (APOOL) 31.6
 LDTP11044  Polyadenylate-binding protein-interacting protein 2 (PAIP2) 31.6
 LDTP08689  Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) 31.3
 LDTP01075  Protein CutA (CUTA) 31.1
 LDTP05868  Protein unc-119 homolog A (UNC119) 30.7
 LDTP02124  Keratin, type I cytoskeletal 18 (KRT18) 30.5
 LDTP01225  Mediator of RNA polymerase II transcription subunit 24 (MED24) 30.5
 LDTP10924  Prohibitin-2 (PHB2) 30.5
 LDTP03775  RNA-binding protein FUS (FUS) 30.5
 LDTP09215  Torsin-1A-interacting protein 2 (TOR1AIP2) 30.1
 LDTP04425  Translocon-associated protein subunit delta (SSR4) 30.1
 LDTP16193  Craniofacial development protein 1 (CFDP1) 29.9
 LDTP00500  Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) 29.9
 LDTP11911  Golgi phosphoprotein 3 (GOLPH3) 29.7
 LDTP06305  WD repeat-containing protein 43 (WDR43) 29.7
 LDTP19924  Protein PBDC1 (PBDC1) 29.4
 LDTP16285  Transducin beta-like protein 2 (TBL2) 29.4
 LDTP11981  Receptor expression-enhancing protein 4 (REEP4) 29.2
 LDTP00887  Calumenin (CALU) 29.0
 LDTP04684  Nucleosome assembly protein 1-like 1 (NAP1L1) 29.0
 LDTP01652  Centrosomal protein 43 (CEP43) 28.8
 LDTP10209  Regulator of microtubule dynamics protein 1 (RMDN1) 28.6
 LDTP03352  Splicing factor U2AF 65 kDa subunit (U2AF2) 28.4
 LDTP00046  NBAS subunit of NRZ tethering complex (NBAS) 27.9
 LDTP09069  Kinetochore protein Spc24 (SPC24) 27.7
 LDTP09151  Calcium uniporter protein, mitochondrial (MCU) 27.3
 LDTP02297  Vimentin (VIM) 27.1
 LDTP07031  Collectin-12 (COLEC12) 26.9
 LDTP05386  Dystonin (DST) 26.9
 LDTP05226  RNA-binding protein 3 (RBM3) 26.7
 LDTP00729  Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) 26.4
 LDTP10965  Nucleosome assembly protein 1-like 4 (NAP1L4) 26.2
 LDTP06210  Golgin subfamily B member 1 (GOLGB1) 25.8
 LDTP06058  Rho guanine nucleotide exchange factor 7 (ARHGEF7) 25.8
 LDTP12956  Coiled-coil domain-containing protein 167 (CCDC167) 25.5
 LDTP13630  Neudesin (NENF) 25.1
 LDTP12395  Large ribosomal subunit protein mL40 (MRPL40) 24.9
 LDTP13162  Mortality factor 4-like protein 1 (MORF4L1) 24.9
 LDTP04917  Proteasome activator complex subunit 3 (PSME3) 24.9
 LDTP11645  SRA stem-loop-interacting RNA-binding protein, mitochondrial (SLIRP) 24.9
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 24.6
 LDTP08793  Armadillo repeat-containing protein 10 (ARMC10) 24.6
 LDTP12591  Kinesin light chain 4 (KLC4) 24.6
 LDTP10849  Regulator of microtubule dynamics protein 3 (RMDN3) 24.4
 LDTP05960  Trophoblast glycoprotein (TPBG) 24.4
 LDTP10185  FAS-associated factor 2 (FAF2) 24.3
 LDTP15976  Large ribosomal subunit protein mL46 (MRPL46) 24.3
 LDTP14136  Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13) 24.3
 LDTP00573  Prefoldin subunit 6 (PFDN6) 24.3
 LDTP04207  Heat shock 70 kDa protein 13 (HSPA13) 24.1
 LDTP01206  Vesicle-trafficking protein SEC22b (SEC22B) 24.1
 LDTP10847  Protein Niban 2 (NIBAN2) 23.9
 LDTP06022  Cold-inducible RNA-binding protein (CIRBP) 23.8
 LDTP10403  DDRGK domain-containing protein 1 (DDRGK1) 23.8
 LDTP03614  Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) 23.8
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 23.6
 LDTP01050  Small ribosomal subunit protein uS14m (MRPS14) 22.9
 LDTP04703  Tumor protein D52 (TPD52) 22.9
 LDTP15863  Large ribosomal subunit protein mL45 (MRPL45) 22.8
 LDTP02736  Myosin light chain 6B (MYL6B) 22.8
 LDTP00223  26S proteasome non-ATPase regulatory subunit 11 (PSMD11) 22.6
 LDTP09410  Protein bicaudal D homolog 2 (BICD2) 22.6
 LDTP12677  DnaJ homolog subfamily C member 11 (DNAJC11) 22.5
 LDTP04094  Large proline-rich protein BAG6 (BAG6) 22.5
 LDTP13967  Transmembrane emp24 domain-containing protein 5 (TMED5) 22.5
 LDTP11978  HAUS augmin-like complex subunit 4 (HAUS4) 22.3
 LDTP01466  HAUS augmin-like complex subunit 5 (HAUS5) 22.2
 LDTP03967  Lamina-associated polypeptide 2, isoform alpha (TMPO) 22.2
 LDTP05318  RNA-binding protein EWS (EWSR1) 22.2
 LDTP11800  Vacuolar protein sorting-associated protein 16 homolog (VPS16) 22.2

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587