Details of the Target

General Information of Target

Target ID LDTP11319
Target Name Threonine--tRNA ligase, mitochondrial (TARS2)
Gene Name TARS2
Gene ID 80222
Synonyms
TARSL1; Threonine--tRNA ligase, mitochondrial; EC 6.1.1.3; Threonyl-tRNA synthetase; ThrRS; Threonyl-tRNA synthetase-like 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAGRLLGKALAAVSLSLALASVTIRSSRCRGIQAFRNSFSSSWFHLNTNVMSGSNGSKEN
SHNKARTSPYPGSKVERSQVPNEKVGWLVEWQDYKPVEYTAVSVLAGPRWADPQISESNF
SPKFNEKDGHVERKSKNGLYEIENGRPRNPAGRTGLVGRGLLGRWGPNHAADPIITRWKR
DSSGNKIMHPVSGKHILQFVAIKRKDCGEWAIPGGMVDPGEKISATLKREFGEEALNSLQ
KTSAEKREIEEKLHKLFSQDHLVIYKGYVDDPRNTDNAWMETEAVNYHDETGEIMDNLML
EAGDDAGKVKWVDINDKLKLYASHSQFIKLVAEKRDAHWSEDSEADCHAL
Target Bioclass
Enzyme
Family
Class-II aminoacyl-tRNA synthetase family
Subcellular location
Mitochondrion matrix
Function
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain.
Uniprot ID
Q9BW92
Ensemble ID
ENST00000369054.6
HGNC ID
HGNC:30740
ChEMBL ID
CHEMBL3351186

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A172 SNV: p.A638V DBIA    Probe Info 
AN3CA SNV: p.H543R DBIA    Probe Info 
HGC27 SNV: p.G447E DBIA    Probe Info 
KELLY SNV: p.Y665H DBIA    Probe Info 
NALM6 SNV: p.R300W DBIA    Probe Info 
OAW28 SNV: p.L3P DBIA    Probe Info 
REH SNV: p.A23V DBIA    Probe Info 
RKO SNV: p.I71T DBIA    Probe Info 
SKMEL2 SNV: p.A75P .
SKMEL5 SNV: p.R11W DBIA    Probe Info 
SUPT1 Deletion: p.P381QfsTer27 DBIA    Probe Info 
TF1 SNV: p.L178M DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 19 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Probe 1
 Probe Info  		Y536(16.83)  LDD3495  [1]
P11
 Probe Info  		7.98  LDD0201  [2]
m-APA
 Probe Info  		11.89  LDD0403  [3]
BTD
 Probe Info  		C185(1.05)  LDD2099  [4]
AHL-Pu-1
 Probe Info  		C506(2.21)  LDD0169  [5]
DBIA
 Probe Info  		C233(9.93); C240(2.32); C603(1.21)  LDD0080  [6]
4-Iodoacetamidophenylacetylene
 Probe Info  		C152(0.00); C322(0.00); C185(0.00); C506(0.00)  LDD0038  [7]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [8]
Lodoacetamide azide
 Probe Info  		C152(0.00); C322(0.00); C185(0.00); C603(0.00)  LDD0037  [7]
IPM
 Probe Info  		N.A.  LDD0005  [9]
TFBX
 Probe Info  		N.A.  LDD0148  [10]
Phosphinate-6
 Probe Info  		C185(0.00); C506(0.00); C240(0.00); C409(0.00)  LDD0018  [11]
Ox-W18
 Probe Info  		W43(0.00); W694(0.00)  LDD2175  [12]
1c-yne
 Probe Info  		N.A.  LDD0228  [13]
Acrolein
 Probe Info  		N.A.  LDD0217  [14]
Methacrolein
 Probe Info  		C603(0.00); C185(0.00)  LDD0218  [14]
AOyne
 Probe Info  		4.70  LDD0443  [15]
NAIA_5
 Probe Info  		C322(0.00); C185(0.00)  LDD2223  [16]
HHS-465
 Probe Info  		N.A.  LDD2240  [17]
PAL-AfBPP Probe
Click To Hide/Show 15 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C158
 Probe Info  		9.32  LDD1838  [18]
C161
 Probe Info  		11.71  LDD1841  [18]
C220
 Probe Info  		13.27  LDD1894  [18]
C246
 Probe Info  		12.47  LDD1919  [18]
C266
 Probe Info  		9.92  LDD1937  [18]
C293
 Probe Info  		18.13  LDD1963  [18]
C350
 Probe Info  		43.41  LDD2011  [18]
C367
 Probe Info  		10.56  LDD2028  [18]
FFF probe11
 Probe Info  		12.81  LDD0471  [19]
FFF probe13
 Probe Info  		20.00  LDD0475  [19]
FFF probe14
 Probe Info  		20.00  LDD0477  [19]
FFF probe2
 Probe Info  		20.00  LDD0463  [19]
FFF probe3
 Probe Info  		13.32  LDD0464  [19]
FFF probe6
 Probe Info  		5.56  LDD0467  [19]
OEA-DA
 Probe Info  		3.37  LDD0046  [20]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0026  4SU-RNA+native RNA HEK-293T C506(2.21)  LDD0169  [5]
 LDCM0214  AC1 HCT 116 C233(1.15); C240(1.04)  LDD0531  [6]
 LDCM0215  AC10 HCT 116 C233(1.01); C240(1.01); C603(0.70)  LDD0532  [6]
 LDCM0216  AC100 HCT 116 C233(0.95); C240(0.95)  LDD0533  [6]
 LDCM0217  AC101 HCT 116 C233(1.07); C240(1.07)  LDD0534  [6]
 LDCM0218  AC102 HCT 116 C233(1.10); C240(1.10)  LDD0535  [6]
 LDCM0219  AC103 HCT 116 C233(0.90); C240(0.90)  LDD0536  [6]
 LDCM0220  AC104 HCT 116 C233(1.14); C240(1.14)  LDD0537  [6]
 LDCM0221  AC105 HCT 116 C233(0.97); C240(0.97)  LDD0538  [6]
 LDCM0222  AC106 HCT 116 C233(1.08); C240(1.08)  LDD0539  [6]
 LDCM0223  AC107 HCT 116 C233(0.95); C240(0.95)  LDD0540  [6]
 LDCM0224  AC108 HCT 116 C233(1.02); C240(1.02)  LDD0541  [6]
 LDCM0225  AC109 HCT 116 C233(1.12); C240(1.12)  LDD0542  [6]
 LDCM0226  AC11 HCT 116 C233(1.03); C240(1.03); C603(0.51)  LDD0543  [6]
 LDCM0227  AC110 HCT 116 C233(0.96); C240(0.96)  LDD0544  [6]
 LDCM0228  AC111 HCT 116 C233(1.12); C240(1.12)  LDD0545  [6]
 LDCM0229  AC112 HCT 116 C233(0.94); C240(0.94)  LDD0546  [6]
 LDCM0230  AC113 HCT 116 C233(0.99); C240(0.99); C603(1.08)  LDD0547  [6]
 LDCM0231  AC114 HCT 116 C233(0.97); C240(0.95); C603(0.96)  LDD0548  [6]
 LDCM0232  AC115 HCT 116 C233(0.93); C240(0.94); C603(1.14)  LDD0549  [6]
 LDCM0233  AC116 HCT 116 C233(1.03); C240(1.04); C603(1.06)  LDD0550  [6]
 LDCM0234  AC117 HCT 116 C233(1.00); C240(0.95); C603(0.95)  LDD0551  [6]
 LDCM0235  AC118 HCT 116 C233(0.92); C240(0.98); C603(0.95)  LDD0552  [6]
 LDCM0236  AC119 HCT 116 C233(1.01); C240(1.05); C603(0.90)  LDD0553  [6]
 LDCM0237  AC12 HCT 116 C233(0.96); C240(0.96); C603(0.82)  LDD0554  [6]
 LDCM0238  AC120 HCT 116 C233(0.97); C240(0.95); C603(0.96)  LDD0555  [6]
 LDCM0239  AC121 HCT 116 C233(1.04); C240(0.82); C603(0.85)  LDD0556  [6]
 LDCM0240  AC122 HCT 116 C233(1.00); C240(0.90); C603(0.94)  LDD0557  [6]
 LDCM0241  AC123 HCT 116 C233(0.96); C240(0.89); C603(0.81)  LDD0558  [6]
 LDCM0242  AC124 HCT 116 C233(0.91); C240(0.84); C603(0.92)  LDD0559  [6]
 LDCM0243  AC125 HCT 116 C233(0.94); C240(0.90); C603(1.00)  LDD0560  [6]
 LDCM0244  AC126 HCT 116 C233(1.08); C240(1.13); C603(1.05)  LDD0561  [6]
 LDCM0245  AC127 HCT 116 C233(0.95); C240(0.98); C603(0.96)  LDD0562  [6]
 LDCM0246  AC128 HCT 116 C233(0.89); C240(0.89)  LDD0563  [6]
 LDCM0247  AC129 HCT 116 C233(0.83); C240(0.83)  LDD0564  [6]
 LDCM0249  AC130 HCT 116 C233(0.83); C240(0.83)  LDD0566  [6]
 LDCM0250  AC131 HCT 116 C233(1.03); C240(1.03)  LDD0567  [6]
 LDCM0251  AC132 HCT 116 C233(0.92); C240(0.92)  LDD0568  [6]
 LDCM0252  AC133 HCT 116 C233(0.86); C240(0.86)  LDD0569  [6]
 LDCM0253  AC134 HCT 116 C233(0.87); C240(0.87)  LDD0570  [6]
 LDCM0254  AC135 HCT 116 C233(1.06); C240(1.06)  LDD0571  [6]
 LDCM0255  AC136 HCT 116 C233(0.96); C240(0.96)  LDD0572  [6]
 LDCM0256  AC137 HCT 116 C233(0.96); C240(0.96)  LDD0573  [6]
 LDCM0257  AC138 HCT 116 C233(0.88); C240(0.88)  LDD0574  [6]
 LDCM0258  AC139 HCT 116 C233(1.03); C240(1.03)  LDD0575  [6]
 LDCM0259  AC14 HCT 116 C233(0.95); C240(0.95); C603(0.33)  LDD0576  [6]
 LDCM0260  AC140 HCT 116 C233(0.91); C240(0.91)  LDD0577  [6]
 LDCM0261  AC141 HCT 116 C233(0.82); C240(0.82)  LDD0578  [6]
 LDCM0262  AC142 HCT 116 C233(0.87); C240(0.87)  LDD0579  [6]
 LDCM0263  AC143 HCT 116 C233(0.96); C240(0.96)  LDD0580  [6]
 LDCM0264  AC144 HCT 116 C233(1.01); C240(1.10)  LDD0581  [6]
 LDCM0265  AC145 HCT 116 C233(1.08); C240(2.86)  LDD0582  [6]
 LDCM0266  AC146 HCT 116 C240(0.64); C233(1.18)  LDD0583  [6]
 LDCM0267  AC147 HCT 116 C233(0.89); C240(1.09)  LDD0584  [6]
 LDCM0268  AC148 HCT 116 C233(0.98); C240(3.20)  LDD0585  [6]
 LDCM0269  AC149 HCT 116 C233(1.06); C240(1.21)  LDD0586  [6]
 LDCM0270  AC15 HCT 116 C603(0.72); C233(1.13); C240(1.13)  LDD0587  [6]
 LDCM0271  AC150 HCT 116 C240(0.60); C233(1.11)  LDD0588  [6]
 LDCM0272  AC151 HCT 116 C240(0.68); C233(1.07)  LDD0589  [6]
 LDCM0273  AC152 HCT 116 C240(0.48); C233(0.99)  LDD0590  [6]
 LDCM0274  AC153 HCT 116 C233(1.37); C240(2.49)  LDD0591  [6]
 LDCM0621  AC154 HCT 116 C233(1.27); C240(1.03)  LDD2158  [6]
 LDCM0622  AC155 HCT 116 C233(1.09); C240(0.82)  LDD2159  [6]
 LDCM0623  AC156 HCT 116 C233(0.95); C240(0.64)  LDD2160  [6]
 LDCM0624  AC157 HCT 116 C233(0.95); C240(0.81)  LDD2161  [6]
 LDCM0276  AC17 HCT 116 C233(0.91); C240(0.91); C506(1.24)  LDD0593  [6]
 LDCM0277  AC18 HCT 116 C233(1.10); C240(1.10); C506(1.20)  LDD0594  [6]
 LDCM0278  AC19 HCT 116 C506(0.97); C233(0.99); C240(0.99)  LDD0595  [6]
 LDCM0279  AC2 HCT 116 C240(1.02); C233(1.13)  LDD0596  [6]
 LDCM0280  AC20 HCT 116 C506(0.95); C233(1.12); C240(1.12)  LDD0597  [6]
 LDCM0281  AC21 HCT 116 C233(1.03); C240(1.03); C506(1.08)  LDD0598  [6]
 LDCM0282  AC22 HCT 116 C233(0.97); C240(0.97); C506(1.45)  LDD0599  [6]
 LDCM0283  AC23 HCT 116 C233(1.07); C240(1.07); C506(1.09)  LDD0600  [6]
 LDCM0284  AC24 HCT 116 C233(1.14); C240(1.14); C506(1.32)  LDD0601  [6]
 LDCM0285  AC25 HCT 116 C233(0.86); C240(0.86); C603(0.96); C506(1.32)  LDD0602  [6]
 LDCM0286  AC26 HCT 116 C233(0.82); C240(0.82); C506(1.15); C603(1.20)  LDD0603  [6]
 LDCM0287  AC27 HCT 116 C233(0.91); C240(0.91); C603(0.96); C506(1.87)  LDD0604  [6]
 LDCM0288  AC28 HCT 116 C233(0.77); C240(0.77); C603(1.02); C506(1.30)  LDD0605  [6]
 LDCM0289  AC29 HCT 116 C233(0.77); C240(0.77); C603(1.00); C506(1.37)  LDD0606  [6]
 LDCM0290  AC3 HCT 116 C240(1.01); C233(1.11)  LDD0607  [6]
 LDCM0291  AC30 HCT 116 C233(0.82); C240(0.82); C603(0.99); C506(1.54)  LDD0608  [6]
 LDCM0292  AC31 HCT 116 C233(0.71); C240(0.71); C603(0.99); C506(1.30)  LDD0609  [6]
 LDCM0293  AC32 HCT 116 C233(0.76); C240(0.76); C603(1.30); C506(1.61)  LDD0610  [6]
 LDCM0294  AC33 HCT 116 C233(0.81); C240(0.81); C603(1.00); C506(1.24)  LDD0611  [6]
 LDCM0295  AC34 HCT 116 C603(0.67); C233(1.00); C240(1.00); C506(1.49)  LDD0612  [6]
 LDCM0296  AC35 HCT 116 C506(0.89); C603(1.02); C233(1.41); C240(1.41)  LDD0613  [6]
 LDCM0297  AC36 HCT 116 C506(0.77); C603(0.93); C233(0.98); C240(0.98)  LDD0614  [6]
 LDCM0298  AC37 HCT 116 C506(0.89); C233(0.93); C240(0.93); C603(1.02)  LDD0615  [6]
 LDCM0299  AC38 HCT 116 C603(1.05); C506(1.06); C233(1.13); C240(1.13)  LDD0616  [6]
 LDCM0300  AC39 HCT 116 C506(0.84); C233(0.95); C240(0.95); C603(1.07)  LDD0617  [6]
 LDCM0301  AC4 HCT 116 C240(1.13); C233(1.32)  LDD0618  [6]
 LDCM0302  AC40 HCT 116 C233(0.91); C240(0.91); C603(1.01); C506(1.64)  LDD0619  [6]
 LDCM0303  AC41 HCT 116 C506(0.89); C233(0.97); C240(0.97); C603(1.05)  LDD0620  [6]
 LDCM0304  AC42 HCT 116 C233(1.04); C240(1.04); C603(1.07); C506(1.10)  LDD0621  [6]
 LDCM0305  AC43 HCT 116 C233(0.95); C240(0.95); C603(1.06); C506(1.06)  LDD0622  [6]
 LDCM0306  AC44 HCT 116 C233(1.01); C240(1.01); C603(1.06); C506(1.21)  LDD0623  [6]
 LDCM0307  AC45 HCT 116 C233(0.82); C240(0.82); C603(1.12); C506(1.23)  LDD0624  [6]
 LDCM0308  AC46 HCT 116 C233(1.13); C240(1.13)  LDD0625  [6]
 LDCM0309  AC47 HCT 116 C233(0.94); C240(0.94)  LDD0626  [6]
 LDCM0310  AC48 HCT 116 C233(1.21); C240(1.21)  LDD0627  [6]
 LDCM0311  AC49 HCT 116 C233(1.85); C240(1.85)  LDD0628  [6]
 LDCM0312  AC5 HCT 116 C240(0.87); C233(0.93)  LDD0629  [6]
 LDCM0313  AC50 HCT 116 C233(1.24); C240(1.24)  LDD0630  [6]
 LDCM0314  AC51 HCT 116 C233(1.38); C240(1.38)  LDD0631  [6]
 LDCM0315  AC52 HCT 116 C233(1.39); C240(1.39)  LDD0632  [6]
 LDCM0316  AC53 HCT 116 C233(1.42); C240(1.42)  LDD0633  [6]
 LDCM0317  AC54 HCT 116 C233(1.24); C240(1.24)  LDD0634  [6]
 LDCM0318  AC55 HCT 116 C233(1.06); C240(1.06)  LDD0635  [6]
 LDCM0319  AC56 HCT 116 C233(1.51); C240(1.51)  LDD0636  [6]
 LDCM0320  AC57 HCT 116 C233(1.01); C240(1.01)  LDD0637  [6]
 LDCM0321  AC58 HCT 116 C233(0.94); C240(0.94)  LDD0638  [6]
 LDCM0322  AC59 HCT 116 C233(0.94); C240(0.94)  LDD0639  [6]
 LDCM0323  AC6 HCT 116 C603(0.65); C233(1.02); C240(1.02)  LDD0640  [6]
 LDCM0324  AC60 HCT 116 C233(1.05); C240(1.05)  LDD0641  [6]
 LDCM0325  AC61 HCT 116 C233(0.98); C240(0.98)  LDD0642  [6]
 LDCM0326  AC62 HCT 116 C233(0.92); C240(0.92)  LDD0643  [6]
 LDCM0327  AC63 HCT 116 C233(0.89); C240(0.89)  LDD0644  [6]
 LDCM0328  AC64 HCT 116 C233(0.94); C240(0.94)  LDD0645  [6]
 LDCM0329  AC65 HCT 116 C233(0.89); C240(0.89)  LDD0646  [6]
 LDCM0330  AC66 HCT 116 C233(0.83); C240(0.83)  LDD0647  [6]
 LDCM0331  AC67 HCT 116 C233(0.79); C240(0.79)  LDD0648  [6]
 LDCM0332  AC68 HCT 116 C233(1.02); C240(1.02)  LDD0649  [6]
 LDCM0333  AC69 HCT 116 C233(0.88); C240(0.88)  LDD0650  [6]
 LDCM0334  AC7 HCT 116 C603(0.60); C233(1.13); C240(1.13)  LDD0651  [6]
 LDCM0335  AC70 HCT 116 C233(0.95); C240(0.95)  LDD0652  [6]
 LDCM0336  AC71 HCT 116 C233(0.96); C240(0.96)  LDD0653  [6]
 LDCM0337  AC72 HCT 116 C233(1.22); C240(1.22)  LDD0654  [6]
 LDCM0338  AC73 HCT 116 C233(0.98); C240(0.98)  LDD0655  [6]
 LDCM0339  AC74 HCT 116 C233(0.92); C240(0.92)  LDD0656  [6]
 LDCM0340  AC75 HCT 116 C233(0.88); C240(0.88)  LDD0657  [6]
 LDCM0341  AC76 HCT 116 C233(1.22); C240(1.22)  LDD0658  [6]
 LDCM0342  AC77 HCT 116 C233(0.96); C240(0.96)  LDD0659  [6]
 LDCM0343  AC78 HCT 116 C233(0.86); C240(0.86)  LDD0660  [6]
 LDCM0344  AC79 HCT 116 C233(1.02); C240(1.02)  LDD0661  [6]
 LDCM0345  AC8 HCT 116 C603(0.54); C233(1.16); C240(1.16)  LDD0662  [6]
 LDCM0346  AC80 HCT 116 C233(1.16); C240(1.16)  LDD0663  [6]
 LDCM0347  AC81 HCT 116 C233(1.25); C240(1.25)  LDD0664  [6]
 LDCM0348  AC82 HCT 116 C233(0.95); C240(0.95)  LDD0665  [6]
 LDCM0349  AC83 HCT 116 C233(1.01); C240(1.01); C603(2.60)  LDD0666  [6]
 LDCM0350  AC84 HCT 116 C233(0.96); C240(0.96); C603(2.11)  LDD0667  [6]
 LDCM0351  AC85 HCT 116 C233(0.96); C240(0.96); C603(2.21)  LDD0668  [6]
 LDCM0352  AC86 HCT 116 C233(1.10); C240(1.10); C603(2.44)  LDD0669  [6]
 LDCM0353  AC87 HCT 116 C233(0.94); C240(0.94); C603(2.36)  LDD0670  [6]
 LDCM0354  AC88 HCT 116 C233(1.06); C240(1.06); C603(2.54)  LDD0671  [6]
 LDCM0355  AC89 HCT 116 C233(1.04); C240(1.04); C603(2.98)  LDD0672  [6]
 LDCM0357  AC90 HCT 116 C233(1.14); C240(1.14); C603(2.35)  LDD0674  [6]
 LDCM0358  AC91 HCT 116 C233(1.03); C240(1.03); C603(2.15)  LDD0675  [6]
 LDCM0359  AC92 HCT 116 C233(1.11); C240(1.11); C603(2.94)  LDD0676  [6]
 LDCM0360  AC93 HCT 116 C233(0.98); C240(0.98); C603(1.84)  LDD0677  [6]
 LDCM0361  AC94 HCT 116 C233(1.04); C240(1.04); C603(2.61)  LDD0678  [6]
 LDCM0362  AC95 HCT 116 C233(0.93); C240(0.93); C603(2.11)  LDD0679  [6]
 LDCM0363  AC96 HCT 116 C233(0.99); C240(0.99); C603(1.94)  LDD0680  [6]
 LDCM0364  AC97 HCT 116 C233(1.01); C240(1.01); C603(2.50)  LDD0681  [6]
 LDCM0365  AC98 HCT 116 C233(1.12); C240(1.12)  LDD0682  [6]
 LDCM0366  AC99 HCT 116 C233(1.00); C240(1.00)  LDD0683  [6]
 LDCM0248  AKOS034007472 HCT 116 C233(1.06); C240(1.06); C603(0.84)  LDD0565  [6]
 LDCM0356  AKOS034007680 HCT 116 C233(1.08); C240(1.08); C603(1.13)  LDD0673  [6]
 LDCM0275  AKOS034007705 HCT 116 C603(0.53); C233(0.98); C240(0.98)  LDD0592  [6]
 LDCM0156  Aniline NCI-H1299 11.89  LDD0403  [3]
 LDCM0020  ARS-1620 HCC44 C233(1.17); C240(1.17)  LDD2171  [6]
 LDCM0088  C45 HEK-293T 7.98  LDD0201  [2]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [14]
 LDCM0632  CL-Sc Hep-G2 C506(20.00)  LDD2227  [16]
 LDCM0367  CL1 HCT 116 C233(1.65); C240(1.65)  LDD0684  [6]
 LDCM0368  CL10 HCT 116 C233(0.68); C240(0.68)  LDD0685  [6]
 LDCM0369  CL100 HCT 116 C240(1.07); C233(1.16)  LDD0686  [6]
 LDCM0370  CL101 HCT 116 C603(0.23); C233(1.16); C240(1.16)  LDD0687  [6]
 LDCM0371  CL102 HCT 116 C603(0.26); C233(1.33); C240(1.33)  LDD0688  [6]
 LDCM0372  CL103 HCT 116 C603(0.29); C233(1.41); C240(1.41)  LDD0689  [6]
 LDCM0373  CL104 HCT 116 C603(0.40); C233(1.11); C240(1.11)  LDD0690  [6]
 LDCM0374  CL105 HCT 116 C233(1.02); C240(1.02); C506(1.68)  LDD0691  [6]
 LDCM0375  CL106 HCT 116 C233(0.97); C240(0.97); C506(1.93)  LDD0692  [6]
 LDCM0376  CL107 HCT 116 C233(0.97); C240(0.97); C506(1.54)  LDD0693  [6]
 LDCM0377  CL108 HCT 116 C233(0.95); C240(0.95); C506(1.36)  LDD0694  [6]
 LDCM0378  CL109 HCT 116 C233(1.09); C240(1.09); C506(1.12)  LDD0695  [6]
 LDCM0379  CL11 HCT 116 C233(0.78); C240(0.78)  LDD0696  [6]
 LDCM0380  CL110 HCT 116 C233(1.15); C240(1.15); C506(1.87)  LDD0697  [6]
 LDCM0381  CL111 HCT 116 C233(1.10); C240(1.10); C506(1.26)  LDD0698  [6]
 LDCM0382  CL112 HCT 116 C603(0.99); C233(1.04); C240(1.04); C506(1.19)  LDD0699  [6]
 LDCM0383  CL113 HCT 116 C233(0.83); C240(0.83); C603(0.85); C506(1.38)  LDD0700  [6]
 LDCM0384  CL114 HCT 116 C603(0.82); C233(1.07); C240(1.07); C506(1.56)  LDD0701  [6]
 LDCM0385  CL115 HCT 116 C603(0.90); C233(0.96); C240(0.96); C506(1.57)  LDD0702  [6]
 LDCM0386  CL116 HCT 116 C233(0.82); C240(0.82); C603(0.89); C506(1.48)  LDD0703  [6]
 LDCM0387  CL117 HCT 116 C233(0.86); C240(0.86); C603(1.02); C506(1.41)  LDD0704  [6]
 LDCM0388  CL118 HCT 116 C233(0.91); C240(0.91); C603(1.12); C506(1.17)  LDD0705  [6]
 LDCM0389  CL119 HCT 116 C506(0.86); C603(0.93); C233(0.97); C240(0.97)  LDD0706  [6]
 LDCM0390  CL12 HCT 116 C233(0.75); C240(0.75)  LDD0707  [6]
 LDCM0391  CL120 HCT 116 C233(1.03); C240(1.03); C603(1.08); C506(1.40)  LDD0708  [6]
 LDCM0392  CL121 HCT 116 C233(1.14); C240(1.14)  LDD0709  [6]
 LDCM0393  CL122 HCT 116 C233(1.32); C240(1.32)  LDD0710  [6]
 LDCM0394  CL123 HCT 116 C233(1.34); C240(1.34)  LDD0711  [6]
 LDCM0395  CL124 HCT 116 C233(1.27); C240(1.27)  LDD0712  [6]
 LDCM0396  CL125 HCT 116 C233(0.93); C240(0.93)  LDD0713  [6]
 LDCM0397  CL126 HCT 116 C233(1.28); C240(1.28)  LDD0714  [6]
 LDCM0398  CL127 HCT 116 C233(0.86); C240(0.86)  LDD0715  [6]
 LDCM0399  CL128 HCT 116 C233(0.96); C240(0.96)  LDD0716  [6]
 LDCM0400  CL13 HCT 116 C233(0.73); C240(0.73)  LDD0717  [6]
 LDCM0401  CL14 HCT 116 C233(1.55); C240(1.55)  LDD0718  [6]
 LDCM0402  CL15 HCT 116 C233(0.72); C240(0.72)  LDD0719  [6]
 LDCM0403  CL16 HCT 116 C233(0.89); C240(0.89)  LDD0720  [6]
 LDCM0404  CL17 HCT 116 C233(0.76); C240(0.76)  LDD0721  [6]
 LDCM0405  CL18 HCT 116 C233(0.39); C240(0.39)  LDD0722  [6]
 LDCM0406  CL19 HCT 116 C233(0.77); C240(0.77)  LDD0723  [6]
 LDCM0407  CL2 HCT 116 C233(0.92); C240(0.92)  LDD0724  [6]
 LDCM0408  CL20 HCT 116 C233(0.58); C240(0.58)  LDD0725  [6]
 LDCM0409  CL21 HCT 116 C233(0.55); C240(0.55)  LDD0726  [6]
 LDCM0410  CL22 HCT 116 C233(0.85); C240(0.85)  LDD0727  [6]
 LDCM0411  CL23 HCT 116 C233(0.59); C240(0.59)  LDD0728  [6]
 LDCM0412  CL24 HCT 116 C233(0.68); C240(0.68)  LDD0729  [6]
 LDCM0413  CL25 HCT 116 C233(0.79); C240(0.79)  LDD0730  [6]
 LDCM0414  CL26 HCT 116 C233(0.68); C240(0.68)  LDD0731  [6]
 LDCM0415  CL27 HCT 116 C233(0.75); C240(0.75)  LDD0732  [6]
 LDCM0416  CL28 HCT 116 C233(0.57); C240(0.57)  LDD0733  [6]
 LDCM0417  CL29 HCT 116 C233(0.65); C240(0.65)  LDD0734  [6]
 LDCM0418  CL3 HCT 116 C233(0.98); C240(0.98)  LDD0735  [6]
 LDCM0419  CL30 HCT 116 C233(0.62); C240(0.62)  LDD0736  [6]
 LDCM0420  CL31 HCT 116 C233(0.96); C240(0.96)  LDD0737  [6]
 LDCM0421  CL32 HCT 116 C233(0.74); C240(0.74)  LDD0738  [6]
 LDCM0422  CL33 HCT 116 C233(0.84); C240(0.84)  LDD0739  [6]
 LDCM0423  CL34 HCT 116 C233(1.30); C240(1.30)  LDD0740  [6]
 LDCM0424  CL35 HCT 116 C233(0.91); C240(0.91)  LDD0741  [6]
 LDCM0425  CL36 HCT 116 C233(0.94); C240(0.94)  LDD0742  [6]
 LDCM0426  CL37 HCT 116 C233(1.05); C240(1.05)  LDD0743  [6]
 LDCM0428  CL39 HCT 116 C233(0.79); C240(0.79)  LDD0745  [6]
 LDCM0429  CL4 HCT 116 C233(0.97); C240(0.97)  LDD0746  [6]
 LDCM0430  CL40 HCT 116 C233(0.74); C240(0.74)  LDD0747  [6]
 LDCM0431  CL41 HCT 116 C233(1.05); C240(1.05)  LDD0748  [6]
 LDCM0432  CL42 HCT 116 C233(1.00); C240(1.00)  LDD0749  [6]
 LDCM0433  CL43 HCT 116 C233(0.95); C240(0.95)  LDD0750  [6]
 LDCM0434  CL44 HCT 116 C233(0.93); C240(0.93)  LDD0751  [6]
 LDCM0435  CL45 HCT 116 C233(1.27); C240(1.27)  LDD0752  [6]
 LDCM0436  CL46 HCT 116 C233(1.45); C240(1.45); C506(0.84)  LDD0753  [6]
 LDCM0437  CL47 HCT 116 C233(1.21); C240(1.21); C506(0.70)  LDD0754  [6]
 LDCM0438  CL48 HCT 116 C233(1.33); C240(1.33); C506(0.81)  LDD0755  [6]
 LDCM0439  CL49 HCT 116 C233(1.18); C240(1.18); C506(0.80)  LDD0756  [6]
 LDCM0440  CL5 HCT 116 C233(0.73); C240(0.73)  LDD0757  [6]
 LDCM0441  CL50 HCT 116 C233(1.16); C240(1.16); C506(0.78)  LDD0758  [6]
 LDCM0442  CL51 HCT 116 C233(1.10); C240(1.10); C506(0.86)  LDD0759  [6]
 LDCM0443  CL52 HCT 116 C233(1.42); C240(1.42); C506(1.07)  LDD0760  [6]
 LDCM0444  CL53 HCT 116 C233(1.58); C240(1.58); C506(0.76)  LDD0761  [6]
 LDCM0445  CL54 HCT 116 C233(1.44); C240(1.44); C506(0.73)  LDD0762  [6]
 LDCM0446  CL55 HCT 116 C233(1.23); C240(1.23); C506(0.70)  LDD0763  [6]
 LDCM0447  CL56 HCT 116 C233(1.00); C240(1.00); C506(1.10)  LDD0764  [6]
 LDCM0448  CL57 HCT 116 C233(1.42); C240(1.42); C506(0.94)  LDD0765  [6]
 LDCM0449  CL58 HCT 116 C233(1.27); C240(1.27); C506(0.77)  LDD0766  [6]
 LDCM0450  CL59 HCT 116 C233(1.08); C240(1.08); C506(0.82)  LDD0767  [6]
 LDCM0451  CL6 HCT 116 C233(0.92); C240(0.92)  LDD0768  [6]
 LDCM0452  CL60 HCT 116 C233(1.25); C240(1.25); C506(0.86)  LDD0769  [6]
 LDCM0453  CL61 HCT 116 C233(1.47); C240(1.47)  LDD0770  [6]
 LDCM0454  CL62 HCT 116 C233(1.59); C240(1.59)  LDD0771  [6]
 LDCM0455  CL63 HCT 116 C233(1.20); C240(1.20)  LDD0772  [6]
 LDCM0456  CL64 HCT 116 C233(1.07); C240(1.07)  LDD0773  [6]
 LDCM0457  CL65 HCT 116 C233(1.05); C240(1.05)  LDD0774  [6]
 LDCM0458  CL66 HCT 116 C233(0.95); C240(0.95)  LDD0775  [6]
 LDCM0459  CL67 HCT 116 C233(0.97); C240(0.97)  LDD0776  [6]
 LDCM0460  CL68 HCT 116 C233(1.55); C240(1.55)  LDD0777  [6]
 LDCM0461  CL69 HCT 116 C233(1.83); C240(1.83)  LDD0778  [6]
 LDCM0462  CL7 HCT 116 C233(0.68); C240(0.68)  LDD0779  [6]
 LDCM0463  CL70 HCT 116 C233(1.05); C240(1.05)  LDD0780  [6]
 LDCM0464  CL71 HCT 116 C233(1.09); C240(1.09)  LDD0781  [6]
 LDCM0465  CL72 HCT 116 C233(0.92); C240(0.92)  LDD0782  [6]
 LDCM0466  CL73 HCT 116 C233(2.42); C240(2.42)  LDD0783  [6]
 LDCM0467  CL74 HCT 116 C233(2.41); C240(2.41)  LDD0784  [6]
 LDCM0469  CL76 HCT 116 C233(1.10); C240(1.10)  LDD0786  [6]
 LDCM0470  CL77 HCT 116 C233(1.27); C240(1.27)  LDD0787  [6]
 LDCM0471  CL78 HCT 116 C233(1.16); C240(1.16)  LDD0788  [6]
 LDCM0472  CL79 HCT 116 C233(1.07); C240(1.07)  LDD0789  [6]
 LDCM0473  CL8 HCT 116 C233(0.96); C240(0.96)  LDD0790  [6]
 LDCM0474  CL80 HCT 116 C233(0.77); C240(0.77)  LDD0791  [6]
 LDCM0475  CL81 HCT 116 C233(1.27); C240(1.27)  LDD0792  [6]
 LDCM0476  CL82 HCT 116 C233(0.96); C240(0.96)  LDD0793  [6]
 LDCM0477  CL83 HCT 116 C233(1.05); C240(1.05)  LDD0794  [6]
 LDCM0478  CL84 HCT 116 C233(0.89); C240(0.89)  LDD0795  [6]
 LDCM0479  CL85 HCT 116 C233(0.94); C240(0.94)  LDD0796  [6]
 LDCM0480  CL86 HCT 116 C233(1.01); C240(1.01)  LDD0797  [6]
 LDCM0481  CL87 HCT 116 C233(1.06); C240(1.06)  LDD0798  [6]
 LDCM0482  CL88 HCT 116 C233(1.02); C240(1.02)  LDD0799  [6]
 LDCM0483  CL89 HCT 116 C233(0.96); C240(0.96)  LDD0800  [6]
 LDCM0484  CL9 HCT 116 C233(0.78); C240(0.78)  LDD0801  [6]
 LDCM0485  CL90 HCT 116 C233(1.32); C240(1.32)  LDD0802  [6]
 LDCM0486  CL91 HCT 116 C233(1.22); C240(1.15)  LDD0803  [6]
 LDCM0487  CL92 HCT 116 C233(1.12); C240(1.14)  LDD0804  [6]
 LDCM0488  CL93 HCT 116 C233(1.13); C240(1.07)  LDD0805  [6]
 LDCM0489  CL94 HCT 116 C233(1.21); C240(1.08)  LDD0806  [6]
 LDCM0490  CL95 HCT 116 C233(1.16); C240(1.10)  LDD0807  [6]
 LDCM0491  CL96 HCT 116 C233(1.61); C240(1.51)  LDD0808  [6]
 LDCM0492  CL97 HCT 116 C233(1.44); C240(1.37)  LDD0809  [6]
 LDCM0493  CL98 HCT 116 C233(1.18); C240(1.05)  LDD0810  [6]
 LDCM0494  CL99 HCT 116 C233(1.23); C240(1.13)  LDD0811  [6]
 LDCM0495  E2913 HEK-293T C185(1.08); C554(1.02); C603(0.86); C322(1.04)  LDD1698  [21]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C185(2.52)  LDD1702  [4]
 LDCM0625  F8 Ramos C185(0.66); C506(1.24)  LDD2187  [22]
 LDCM0572  Fragment10 Ramos C185(0.70); C506(0.77)  LDD2189  [22]
 LDCM0573  Fragment11 Ramos C185(0.15); C506(1.79)  LDD2190  [22]
 LDCM0574  Fragment12 Ramos C185(0.82); C506(0.58)  LDD2191  [22]
 LDCM0575  Fragment13 Ramos C185(0.84); C506(0.45)  LDD2192  [22]
 LDCM0576  Fragment14 Ramos C185(0.83); C506(1.71)  LDD2193  [22]
 LDCM0579  Fragment20 Ramos C185(1.01); C506(0.68)  LDD2194  [22]
 LDCM0580  Fragment21 Ramos C185(0.99); C506(0.94)  LDD2195  [22]
 LDCM0582  Fragment23 Ramos C185(0.95); C506(0.67)  LDD2196  [22]
 LDCM0578  Fragment27 Ramos C185(0.88); C506(0.85)  LDD2197  [22]
 LDCM0586  Fragment28 Ramos C185(0.69); C506(0.66)  LDD2198  [22]
 LDCM0588  Fragment30 Ramos C185(1.05); C506(0.74)  LDD2199  [22]
 LDCM0589  Fragment31 Ramos C185(0.93); C506(0.65)  LDD2200  [22]
 LDCM0590  Fragment32 Ramos C185(0.65); C506(0.68)  LDD2201  [22]
 LDCM0468  Fragment33 HCT 116 C233(1.12); C240(1.12)  LDD0785  [6]
 LDCM0596  Fragment38 Ramos C185(0.87); C506(0.33)  LDD2203  [22]
 LDCM0566  Fragment4 Ramos C185(0.75); C506(0.46)  LDD2184  [22]
 LDCM0427  Fragment51 HCT 116 C233(1.13); C240(1.13)  LDD0744  [6]
 LDCM0610  Fragment52 Ramos C185(0.70); C506(0.38)  LDD2204  [22]
 LDCM0614  Fragment56 Ramos C185(1.03); C506(0.68)  LDD2205  [22]
 LDCM0569  Fragment7 Ramos C185(0.77); C506(0.93)  LDD2186  [22]
 LDCM0571  Fragment9 Ramos C185(1.06); C506(1.06)  LDD2188  [22]
 LDCM0107  IAA HeLa N.A.  LDD0221  [14]
 LDCM0022  KB02 HCT 116 C233(9.93); C240(2.32); C603(1.21)  LDD0080  [6]
 LDCM0023  KB03 HCT 116 C233(8.10); C240(2.56); C603(1.55)  LDD0081  [6]
 LDCM0024  KB05 HCT 116 C233(13.12); C240(2.30); C603(1.27)  LDD0082  [6]
 LDCM0109  NEM HeLa N.A.  LDD0227  [14]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C185(1.05)  LDD2099  [4]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C185(0.76)  LDD2107  [4]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C185(1.19)  LDD2119  [4]
 LDCM0627  NUDT7-COV-1 HEK-293T C322(4.22)  LDD2206  [23]
 LDCM0628  OTUB2-COV-1 HEK-293T C322(0.41)  LDD2207  [23]
 LDCM0021  THZ1 HCT 116 C233(1.17); C240(1.17)  LDD2173  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Threonine--tRNA ligase 2, cytoplasmic (TARS3) Class-II aminoacyl-tRNA synthetase family A2RTX5
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) . Q9Y680
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Voltage-gated purine nucleotide uniporter SLC17A9 (SLC17A9) Sodium/anion cotransporter family Q9BYT1
Cytokine and receptor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Tumor necrosis factor receptor superfamily member 10D (TNFRSF10D) . Q9UBN6
Other
Click To Hide/Show 7 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ankyrin repeat and SOCS box protein 6 (ASB6) Ankyrin SOCS box (ASB) family Q9NWX5
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) ARL6ip family Q15041
DNA damage-inducible transcript 4-like protein (DDIT4L) DDIT4 family Q96D03
Protein MAL2 (MAL2) MAL family Q969L2
Perilipin-3 (PLIN3) Perilipin family O60664
Vesicle transport protein SFT2A (SFT2D1) SFT2 family Q8WV19
Synaptophysin-like protein 1 (SYPL1) Synaptophysin/synaptobrevin family Q16563

The Drug(s) Related To This Target

Approved
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Threonine Small molecular drug DB00156

References

1 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
2 Discovery of Potent and Selective Inhibitors against Protein-Derived Electrophilic Cofactors. J Am Chem Soc. 2022 Mar 30;144(12):5377-5388. doi: 10.1021/jacs.1c12748. Epub 2022 Mar 2.
3 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
4 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
5 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
8 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
9 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
10 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
11 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
12 Oxidative cyclization reagents reveal tryptophan cation- interactions. Nature. 2024 Mar;627(8004):680-687. doi: 10.1038/s41586-024-07140-6. Epub 2024 Mar 6.
Mass spectrometry data entry: PXD001377 , PXD005252
13 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
14 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
15 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
16 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
17 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010
18 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
19 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
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Mass spectrometry data entry: PXD007570
21 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
22 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
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