Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C246  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 142 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00697  Cytochrome b5 type B (CYB5B) 99.7
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 79.3
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 54.6
 LDTP15328  Dolichyldiphosphatase 1 (DOLPP1) 52.0
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 50.2
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 45.6
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 44.6
 LDTP06618  ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) 42.2
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 41.6
 LDTP02359  Heme oxygenase 1 (HMOX1) 40.8
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 39.9
 LDTP12873  CDGSH iron-sulfur domain-containing protein 1 (CISD1) 39.9
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 38.9
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 37.8
 LDTP00325  Pirin (PIR) 36.5
 LDTP07831  Transmembrane protein with metallophosphoesterase domain (TMPPE) 36.5
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 35.5
 LDTP19745  ADP-ribosylation factor-like protein 10 (ARL10) 35.0
 LDTP05905  Acid ceramidase (ASAH1) 33.8
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 33.8
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 31.1
 LDTP03540  Heme oxygenase 2 (HMOX2) 30.1
 LDTP06986  Rab-like protein 3 (RABL3) 29.7
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 29.4
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 29.2
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1) 29.0
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) 28.8
 LDTP02922  CTP synthase 1 (CTPS1) 28.6
 LDTP06150  DNA replication licensing factor MCM6 (MCM6) 28.2
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 27.9
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 26.9
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 26.2
 LDTP05408  Antigen peptide transporter 1 (TAP1) 26.0
 LDTP01065  E3 ubiquitin-protein ligase TRIM13 (TRIM13) 25.8
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 25.6
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 25.6
 LDTP11273  N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) 25.5
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 25.3
 LDTP03145  Catechol O-methyltransferase (COMT) 24.8
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 24.6
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 23.9
 LDTP05476  3-ketodihydrosphingosine reductase (KDSR) 23.8
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 23.8
 LDTP10550  Dehydrogenase/reductase SDR family member 1 (DHRS1) 23.4
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 22.9
 LDTP08455  Palmitoyltransferase ZDHHC13 (ZDHHC13) 22.2
 LDTP15480  Prenylcysteine oxidase-like (PCYOX1L) 22.2
 LDTP10329  Ceramide synthase 2 (CERS2) 21.9
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 21.9
 LDTP01389  Delta(14)-sterol reductase TM7SF2 (TM7SF2) 21.7
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 21.7
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 21.0
 LDTP12867  Very-long-chain enoyl-CoA reductase (TECR) 20.8
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 20.7
 LDTP01649  Phosphatidate cytidylyltransferase 2 (CDS2) 19.8
 LDTP10177  Medium-chain acyl-CoA ligase ACSF2, mitochondrial (ACSF2) 19.3
 LDTP10020  Ras-related protein Rab-24 (RAB24) 19.0
 LDTP05638  CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (ST3GAL4) 18.9
 LDTP04531  Hexokinase-2 (HK2) 18.8
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 18.8
 LDTP02896  Sphingomyelin phosphodiesterase (SMPD1) 18.8
 LDTP02385  Leukotriene A-4 hydrolase (LTA4H) 18.6
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 18.4
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 18.4
 LDTP09666  Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) 18.1
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 17.9
 LDTP09251  Atlastin-2 (ATL2) 17.8
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 17.6
 LDTP03189  Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) 17.5
 LDTP13352  GTP:AMP phosphotransferase AK3, mitochondrial (AK3) 17.5
 LDTP10930  Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) 17.4
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 17.1
 LDTP01560  NADH dehydrogenase 1 subunit C2 (NDUFC2) 17.0
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 16.9
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 16.7
 LDTP04581  Holocytochrome c-type synthase (HCCS) 16.7
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 16.4
 LDTP03779  Copper-transporting ATPase 2 (ATP7B) 16.4
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 16.4
 LDTP07931  Heme A synthase COX15 (COX15) 16.3
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 16.3
 LDTP06142  Squalene monooxygenase (SQLE) 16.3
 LDTP11127  ADP-dependent glucokinase (ADPGK) 16.2
 LDTP02505  Lysosomal protective protein (CTSA) 16.2
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) 16.0
 LDTP14189  UbiA prenyltransferase domain-containing protein 1 (UBIAD1) 15.9
 LDTP09188  Lysophosphatidylcholine acyltransferase 1 (LPCAT1) 15.8
 LDTP10182  TLC domain-containing protein 1 (TLCD1) 15.8
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 15.7
 LDTP04358  Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) 15.5
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 15.5
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 15.1
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 15.1
 LDTP13620  Lysosomal thioesterase PPT2 (PPT2) 15.0
 LDTP02539  Lysosomal acid phosphatase (ACP2) 14.9
 LDTP15962  Protein-L-histidine N-pros-methyltransferase (METTL9) 14.9
 LDTP05029  Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) 14.8
 LDTP00907  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) 14.8
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 14.8
 LDTP11081  NAD-capped RNA hydrolase NUDT12 (NUDT12) 14.6
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 14.5
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 14.4
 LDTP03854  Vitamin K-dependent gamma-carboxylase (GGCX) 14.4
 LDTP02254  ATP-dependent translocase ABCB1 (ABCB1) 14.3
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 14.3
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 14.3
 LDTP12056  Thiol S-methyltransferase TMT1A (TMT1A) 14.3
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 14.2
 LDTP08790  Mitochondrial cardiolipin hydrolase (PLD6) 14.2
 LDTP12253  Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) 14.0
 LDTP19851  Isochorismatase domain-containing protein 1 (ISOC1) 13.9
 LDTP12720  Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) 13.9
 LDTP05958  Ras-related protein Rab-32 (RAB32) 13.9
 LDTP00950  Dynamin-like 120 kDa protein, mitochondrial (OPA1) 13.8
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 13.8
 LDTP05758  S-methyl-5'-thioadenosine phosphorylase (MTAP) 13.7
 LDTP07813  Sulfhydryl oxidase 2 (QSOX2) 13.7
 LDTP10318  Ubiquitin thioesterase OTUB1 (OTUB1) 13.6
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 13.5
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) 13.3
 LDTP13486  Long-chain-fatty-acid--CoA ligase 6 (ACSL6) 13.3
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 13.2
 LDTP07591  Neutral cholesterol ester hydrolase 1 (NCEH1) 13.2
 LDTP13986  Vesicle transport protein GOT1B (GOLT1B) 13.2
 LDTP09095  Diacylglycerol lipase-beta (DAGLB) 13.1
 LDTP09835  GPI-anchor transamidase (PIGK) 13.1
 LDTP00783  Beta-1,4-glucuronyltransferase 1 (B4GAT1) 13.0
 LDTP12318  Calcium-independent phospholipase A2-gamma (PNPLA8) 13.0
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 12.9
 LDTP06905  Acylglycerol kinase, mitochondrial (AGK) 12.8
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 12.8
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 12.7
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS) 12.7
 LDTP03198  Ferrochelatase, mitochondrial (FECH) 12.5
 LDTP11319  Threonine--tRNA ligase, mitochondrial (TARS2) 12.5
 LDTP13675  COP9 signalosome complex subunit 3 (COPS3) 12.4
 LDTP07158  Integrator complex subunit 11 (INTS11) 12.4
 LDTP11209  Phosphatidylinositol 4-kinase type 2-alpha (PI4K2A) 12.4
 LDTP11723  Cytosolic 5'-nucleotidase 3A (NT5C3A) 12.3
 LDTP12763  Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) 12.3
 LDTP12470  GTP-binding protein SAR1a (SAR1A) 12.3
 LDTP09396  Minor histocompatibility antigen H13 (HM13) 12.2
Transporter and channel
Click to Show/Hide to Show 117 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 88.6
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 66.3
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 64.4
 LDTP16813  Tetraspanin-3 (TSPAN3) 57.7
 LDTP15948  Transmembrane protein 126A (TMEM126A) 57.3
 LDTP01804  ATP synthase subunit a (MT-ATP6) 55.7
 LDTP15481  Transmembrane protein 87A (TMEM87A) 55.7
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 53.4
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 52.3
 LDTP20002  Transmembrane protein 160 (TMEM160) 52.0
 LDTP10036  BOS complex subunit NCLN (NCLN) 48.2
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 48.2
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 47.2
 LDTP07236  Protein GPR107 (GPR107) 44.3
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 43.1
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 42.8
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 41.9
 LDTP04956  Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) 40.8
 LDTP05900  Metaxin-1 (MTX1) 39.4
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 38.9
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 38.6
 LDTP07156  Protein wntless homolog (WLS) 38.1
 LDTP08881  Transmembrane protein 199 (TMEM199) 36.0
 LDTP01542  Golgi SNAP receptor complex member 1 (GOSR1) 32.7
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 31.8
 LDTP11615  Protein tweety homolog 3 (TTYH3) 31.1
 LDTP06365  Transmembrane emp24 domain-containing protein 2 (TMED2) 30.1
 LDTP18153  Major facilitator superfamily domain-containing protein 3 (MFSD3) 29.4
 LDTP11245  Derlin-1 (DERL1) 27.3
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 26.4
 LDTP01455  Erlin-2 (ERLIN2) 24.9
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 24.9
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 24.8
 LDTP10065  Transmembrane protein 230 (TMEM230) 24.8
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 24.6
 LDTP09294  Proton-coupled zinc antiporter SLC30A5 (SLC30A5) 24.4
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 24.4
 LDTP11250  MICOS complex subunit MIC26 (APOO) 24.3
 LDTP02562  Lysosome-associated membrane glycoprotein 1 (LAMP1) 23.6
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 23.4
 LDTP15648  BRI3-binding protein (BRI3BP) 22.6
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 22.6
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 22.3
 LDTP02215  Prosaposin (PSAP) 22.3
 LDTP01671  STARD3 N-terminal-like protein (STARD3NL) 22.2
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 22.0
 LDTP03559  High affinity cationic amino acid transporter 1 (SLC7A1) 21.6
 LDTP01234  Erlin-1 (ERLIN1) 21.0
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 20.7
 LDTP16190  Protein FAM8A1 (FAM8A1) 20.7
 LDTP04501  Importin subunit alpha-1 (KPNA2) 20.4
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 19.8
 LDTP01380  Wolframin (WFS1) 19.8
 LDTP07467  Rhomboid domain-containing protein 2 (RHBDD2) 19.7
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 19.4
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 19.3
 LDTP09333  Golgin subfamily A member 5 (GOLGA5) 18.6
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 18.4
 LDTP15979  Transmembrane protein 245 (TMEM245) 18.4
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 18.3
 LDTP14181  Peroxisomal membrane protein PEX16 (PEX16) 18.1
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 18.1
 LDTP10669  Melanoma inhibitory activity protein 2 (MIA2) 18.0
 LDTP04459  H(+)/Cl(-) exchange transporter 3 (CLCN3) 17.8
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 17.5
 LDTP01200  Peroxisomal membrane protein PEX14 (PEX14) 17.5
 LDTP04787  Transmembrane protein 33 (TMEM33) 17.5
 LDTP00882  Glucose-6-phosphate exchanger SLC37A4 (SLC37A4) 17.4
 LDTP01180  Programmed cell death protein 6 (PDCD6) 17.4
 LDTP04237  Protein ERGIC-53 (LMAN1) 17.1
 LDTP11213  Nucleoporin NDC1 (NDC1) 16.8
 LDTP00541  NPC intracellular cholesterol transporter 1 (NPC1) 16.7
 LDTP13164  Protein sel-1 homolog 1 (SEL1L) 16.7
 LDTP01060  PRA1 family protein 2 (PRAF2) 16.6
 LDTP13833  Integral membrane protein 2B (ITM2B) 16.3
 LDTP12191  Vezatin (VEZT) 16.3
 LDTP14200  Mitochondrial ornithine transporter 1 (SLC25A15) 15.8
 LDTP07058  Transmembrane protein 201 (TMEM201) 15.1
 LDTP06221  StAR-related lipid transfer protein 3 (STARD3) 15.0
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 15.0
 LDTP05667  Syntaxin-4 (STX4) 15.0
 LDTP11116  45 kDa calcium-binding protein (SDF4) 14.8
 LDTP13969  Transmembrane emp24 domain-containing protein 7 (TMED7) 14.8
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 14.7
 LDTP08030  Autophagy-related protein 9A (ATG9A) 14.6
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 14.6
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 14.5
 LDTP08279  Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) 14.5
 LDTP10931  Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (SDHC) 14.5
 LDTP07667  Transmembrane protein 205 (TMEM205) 14.5
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 14.4
 LDTP14084  Sorting and assembly machinery component 50 homolog (SAMM50) 14.4
 LDTP07610  Proton-coupled zinc antiporter SLC30A9, mitochondrial (SLC30A9) 14.2
 LDTP12207  Putative divalent cation/proton antiporter TMEM165 (TMEM165) 14.1
 LDTP06945  Sigma intracellular receptor 2 (TMEM97) 14.1
 LDTP13943  Thioredoxin-related transmembrane protein 2 (TMX2) 14.1
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 13.9
 LDTP00010  Intraflagellar transport protein 56 (IFT56) 13.9
 LDTP02544  Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) 13.9
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 13.7
 LDTP07531  Sideroflexin-4 (SFXN4) 13.5
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) 13.3
 LDTP02655  Lysosome-associated membrane glycoprotein 2 (LAMP2) 13.2
 LDTP09288  Vang-like protein 1 (VANGL1) 13.2
 LDTP13393  Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) 13.1
 LDTP15845  Transmembrane 9 superfamily member 2 (TM9SF2) 13.1
 LDTP07583  Transmembrane protein 65 (TMEM65) 13.1
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 13.0
 LDTP13320  Prenylated Rab acceptor protein 1 (RABAC1) 12.9
 LDTP13256  SUN domain-containing protein 2 (SUN2) 12.8
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 12.6
 LDTP00872  Peroxisomal membrane protein PMP34 (SLC25A17) 12.6
 LDTP00262  Acetyl-coenzyme A transporter 1 (SLC33A1) 12.5
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 12.5
 LDTP13953  Endophilin-B1 (SH3GLB1) 12.4
 LDTP07477  Transmembrane protein 214 (TMEM214) 12.4
 LDTP01601  Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) 12.2
Transcription factor
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP06415  Transcriptional enhancer factor TEF-3 (TEAD4) 44.6
 LDTP09694  Paraspeckle component 1 (PSPC1) 18.1
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 16.0
Immunoglobulin
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03772  Basigin (BSG) 18.1
 LDTP05572  Leukocyte surface antigen CD47 (CD47) 16.3
 LDTP11441  Cell adhesion molecule 1 (CADM1) 12.6
Other
Click to Show/Hide to Show 101 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11076  Apolipoprotein L2 (APOL2) 99.7
 LDTP01522  Reticulon-3 (RTN3) 83.9
 LDTP14939  Membralin (TMEM259) 78.2
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 76.6
 LDTP16099  p53 and DNA damage-regulated protein 1 (PDRG1) 61.4
 LDTP05160  Nucleobindin-2 (NUCB2) 55.3
 LDTP16006  Optic atrophy 3 protein (OPA3) 53.1
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 52.7
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 52.7
 LDTP00986  Syntaxin-10 (STX10) 49.2
 LDTP10056  Protein FAM162A (FAM162A) 45.3
 LDTP00859  Synaptogyrin-2 (SYNGR2) 45.3
 LDTP08796  Protein SYS1 homolog (SYS1) 44.6
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 41.4
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 41.4
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 41.1
 LDTP00850  ER lumen protein-retaining receptor 3 (KDELR3) 39.9
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 39.7
 LDTP19780  Keratinocyte-associated transmembrane protein 2 (KCT2) 37.5
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 36.5
 LDTP12412  Reticulon-4 (RTN4) 35.5
 LDTP13086  Syntaxin-18 (STX18) 34.3
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 34.1
 LDTP15240  LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) 32.7
 LDTP08224  Protein LYRIC (MTDH) 31.3
 LDTP18883  Protein CEBPZOS (CEBPZOS) 28.4
 LDTP12982  Mitochondrial import receptor subunit TOM7 homolog (TOMM7) 27.7
 LDTP19785  Transmembrane protein 35B (TMEM35B) 26.9
 LDTP02927  Ganglioside GM2 activator (GM2A) 26.5
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 25.6
 LDTP13606  Mammalian ependymin-related protein 1 (EPDR1) 23.6
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 23.1
 LDTP15095  Receptor expression-enhancing protein 3 (REEP3) 23.1
 LDTP19963  TraB domain-containing protein (TRABD) 22.3
 LDTP12642  CYFIP-related Rac1 interactor B (CYRIB) 22.2
 LDTP01466  HAUS augmin-like complex subunit 5 (HAUS5) 22.2
 LDTP14458  Tetraspanin-6 (TSPAN6) 21.6
 LDTP15887  Lipase maturation factor 2 (LMF2) 20.1
 LDTP16080  Protein FAM114A2 (FAM114A2) 19.8
 LDTP10775  Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) 19.7
 LDTP05277  Protein SET (SET) 19.7
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 19.4
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 19.0
 LDTP09870  Signal transducing adapter molecule 1 (STAM) 19.0
 LDTP17003  Matrix-remodeling-associated protein 7 (MXRA7) 18.9
 LDTP06097  Reticulocalbin-2 (RCN2) 18.9
 LDTP13797  HIG1 domain family member 1A, mitochondrial (HIGD1A) 18.5
 LDTP01494  Protein YIF1A (YIF1A) 18.5
 LDTP06291  ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) 18.3
 LDTP13954  Complex I intermediate-associated protein 30, mitochondrial (NDUFAF1) 17.5
 LDTP05375  Nucleobindin-1 (NUCB1) 17.3
 LDTP04684  Nucleosome assembly protein 1-like 1 (NAP1L1) 16.7
 LDTP15398  Protein FAM177A1 (FAM177A1) 16.7
 LDTP00199  HCLS1-associated protein X-1 (HAX1) 16.4
 LDTP16116  BSD domain-containing protein 1 (BSDC1) 16.3
 LDTP11911  Golgi phosphoprotein 3 (GOLPH3) 16.2
 LDTP11906  Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) 16.2
 LDTP03352  Splicing factor U2AF 65 kDa subunit (U2AF2) 16.1
 LDTP00729  Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) 15.8
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 15.7
 LDTP06948  Protein YIF1B (YIF1B) 15.6
 LDTP08606  Nurim (NRM) 15.5
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) 15.3
 LDTP14126  Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) 15.0
 LDTP07891  Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) 14.9
 LDTP08300  Reticulophagy regulator 3 (RETREG3) 14.8
 LDTP02124  Keratin, type I cytoskeletal 18 (KRT18) 14.7
 LDTP14259  Testis-expressed protein 264 (TEX264) 14.7
 LDTP02180  Neurofilament light polypeptide (NEFL) 14.2
 LDTP07718  MICOS complex subunit MIC27 (APOOL) 13.9
 LDTP18569  PRELI domain containing protein 3B (PRELID3B) 13.7
 LDTP11978  HAUS augmin-like complex subunit 4 (HAUS4) 13.6
 LDTP00779  Trans-Golgi network integral membrane protein 2 (TGOLN2) 13.6
 LDTP06868  Angiomotin (AMOT) 13.5
 LDTP10275  Mitochondrial potassium channel (CCDC51) 13.5
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 13.5
 LDTP16107  TBC1 domain family member 13 (TBC1D13) 13.5
 LDTP12677  DnaJ homolog subfamily C member 11 (DNAJC11) 13.4
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 13.4
 LDTP06587  Survival motor neuron protein (SMN1; SMN2) 13.4
 LDTP10965  Nucleosome assembly protein 1-like 4 (NAP1L4) 13.3
 LDTP03926  Centrin-2 (CETN2) 13.2
 LDTP07318  HAUS augmin-like complex subunit 3 (HAUS3) 13.2
 LDTP15793  Protein FAM210A (FAM210A) 13.2
 LDTP10357  RUS family member 1 (RUSF1) 13.2
 LDTP10924  Prohibitin-2 (PHB2) 13.0
 LDTP08248  NLR family member X1 (NLRX1) 12.9
 LDTP00871  Microtubule nucleation factor SSNA1 (SSNA1) 12.7
 LDTP11113  Receptor expression-enhancing protein 2 (REEP2) 12.7
 LDTP02297  Vimentin (VIM) 12.6
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 12.4
 LDTP12379  Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) 12.4
 LDTP11326  FUN14 domain-containing protein 2 (FUNDC2) 12.4
 LDTP00632  Syntaxin-7 (STX7) 12.4
 LDTP01359  Dynactin subunit 3 (DCTN3) 12.3
 LDTP10046  Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) 12.3
 LDTP00223  26S proteasome non-ATPase regulatory subunit 11 (PSMD11) 12.2
 LDTP08320  Ankyrin repeat domain-containing protein 46 (ANKRD46) 12.2
 LDTP08154  Large ribosomal subunit protein uL10m (MRPL10) 12.2
 LDTP09787  Nicastrin (NCSTN) 12.2
 LDTP03775  RNA-binding protein FUS (FUS) 12.2

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587