Details of the Target

General Information of Target

Target ID LDTP02385
Target Name Leukotriene A-4 hydrolase (LTA4H)
Gene Name LTA4H
Gene ID 4048
Synonyms
LTA4; Leukotriene A-4 hydrolase; LTA-4 hydrolase; EC 3.3.2.6; Leukotriene A(4) hydrolase; Tripeptide aminopeptidase LTA4H; EC 3.4.11.4
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDL
TIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLT
PEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP
DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETES
MLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISH
SWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET
HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSI
TTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAK
EDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWL
RLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVT
AMLVGKDLKVD
Target Type
Successful
Target Bioclass
Enzyme
Family
Peptidase M1 family
Subcellular location
Cytoplasm
Function
Bifunctional zinc metalloenzyme that comprises both epoxide hydrolase (EH) and aminopeptidase activities. Acts as an epoxide hydrolase to catalyze the conversion of LTA4 to the pro-inflammatory mediator leukotriene B4 (LTB4). Has also aminopeptidase activity, with high affinity for N-terminal arginines of various synthetic tripeptides. In addition to its pro-inflammatory EH activity, may also counteract inflammation by its aminopeptidase activity, which inactivates by cleavage another neutrophil attractant, the tripeptide Pro-Gly-Pro (PGP), a bioactive fragment of collagen generated by the action of matrix metalloproteinase-9 (MMP9) and prolylendopeptidase (PREPL). Involved also in the biosynthesis of resolvin E1 and 18S-resolvin E1 from eicosapentaenoic acid, two lipid mediators that show potent anti-inflammatory and pro-resolving actions.
TTD ID
T03691
Uniprot ID
P09960
DrugMap ID
TTXZEAJ
Ensemble ID
ENST00000228740.7
HGNC ID
HGNC:6710
ChEMBL ID
CHEMBL4618

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HCT15 SNV: p.R569Q DBIA    Probe Info 
LNCaP clone FGC SNV: p.L119P; p.T311N DBIA    Probe Info 
NCIH1048 SNV: p.V437G DBIA    Probe Info 
NCIH2286 SNV: p.L76F .
RH41 SNV: p.D258V DBIA    Probe Info 
SKMEL5 SNV: p.L284P DBIA    Probe Info 
SUPT1 SNV: p.P180S DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 34 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C-Sul
 Probe Info  		2.12  LDD0066  [1]
TH211
 Probe Info  		Y131(20.00); Y589(20.00); Y324(13.58); Y233(6.80)  LDD0257  [2]
TH216
 Probe Info  		Y233(19.76)  LDD0259  [2]
STPyne
 Probe Info  		K20(1.87); K337(5.56); K519(10.00); K573(7.58)  LDD0277  [3]
BTD
 Probe Info  		C147(1.89); C543(2.73)  LDD1699  [4]
ONAyne
 Probe Info  		N.A.  LDD0273  [3]
Probe 1
 Probe Info  		Y233(23.82); Y525(8.34)  LDD3495  [5]
DBIA
 Probe Info  		C147(0.82)  LDD3311  [6]
JZ128-DTB
 Probe Info  		N.A.  LDD0462  [7]
THZ1-DTB
 Probe Info  		C275(0.96)  LDD0460  [7]
HHS-475
 Probe Info  		Y384(0.79); Y379(0.86); Y233(0.98)  LDD0264  [8]
IPM
 Probe Info  		C543(2.41)  LDD1702  [4]
5E-2FA
 Probe Info  		H498(0.00); H140(0.00)  LDD2235  [9]
ATP probe
 Probe Info  		K606(0.00); K609(0.00); K225(0.00); K580(0.00)  LDD0199  [10]
m-APA
 Probe Info  		H498(0.00); H129(0.00)  LDD2231  [9]
4-Iodoacetamidophenylacetylene
 Probe Info  		C147(0.00); C26(0.00)  LDD0038  [11]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [12]
Lodoacetamide azide
 Probe Info  		C147(0.00); C26(0.00); C141(0.00); C136(0.00)  LDD0037  [11]
NAIA_4
 Probe Info  		C8(0.00); C200(0.00); C275(0.00)  LDD2226  [13]
WYneC
 Probe Info  		N.A.  LDD0014  [14]
WYneN
 Probe Info  		N.A.  LDD0021  [14]
Compound 10
 Probe Info  		N.A.  LDD2216  [15]
NPM
 Probe Info  		N.A.  LDD0016  [14]
PF-06672131
 Probe Info  		N.A.  LDD0152  [16]
SF
 Probe Info  		K519(0.00); K573(0.00); Y379(0.00); K386(0.00)  LDD0028  [17]
TFBX
 Probe Info  		N.A.  LDD0148  [18]
Ox-W18
 Probe Info  		W118(0.00); W222(0.00)  LDD2175  [19]
1c-yne
 Probe Info  		K480(0.00); K83(0.00); K493(0.00)  LDD0228  [20]
Acrolein
 Probe Info  		C8(0.00); C17(0.00)  LDD0217  [21]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [21]
Methacrolein
 Probe Info  		C147(0.00); C8(0.00)  LDD0218  [21]
W1
 Probe Info  		E78(0.00); Y74(0.00); R79(0.00)  LDD0236  [22]
NAIA_5
 Probe Info  		C147(0.00); C26(0.00); C200(0.00); C8(0.00)  LDD2223  [13]
HHS-465
 Probe Info  		K386(0.00); K573(0.00); Y233(0.00); Y379(0.00)  LDD2240  [23]
PAL-AfBPP Probe
Click To Hide/Show 50 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C022
 Probe Info  		8.06  LDD1728  [24]
C072
 Probe Info  		28.44  LDD1768  [24]
C092
 Probe Info  		22.47  LDD1783  [24]
C129
 Probe Info  		7.73  LDD1811  [24]
C139
 Probe Info  		10.70  LDD1821  [24]
C140
 Probe Info  		41.07  LDD1822  [24]
C143
 Probe Info  		16.22  LDD1825  [24]
C161
 Probe Info  		11.16  LDD1841  [24]
C163
 Probe Info  		12.47  LDD1843  [24]
C166
 Probe Info  		52.71  LDD1846  [24]
C186
 Probe Info  		8.88  LDD1864  [24]
C187
 Probe Info  		19.70  LDD1865  [24]
C196
 Probe Info  		9.71  LDD1872  [24]
C206
 Probe Info  		28.44  LDD1881  [24]
C211
 Probe Info  		32.67  LDD1885  [24]
C229
 Probe Info  		12.13  LDD1902  [24]
C231
 Probe Info  		13.93  LDD1904  [24]
C232
 Probe Info  		60.55  LDD1905  [24]
C240
 Probe Info  		16.22  LDD1913  [24]
C244
 Probe Info  		19.16  LDD1917  [24]
C245
 Probe Info  		9.85  LDD1918  [24]
C246
 Probe Info  		18.64  LDD1919  [24]
C249
 Probe Info  		13.55  LDD1922  [24]
C252
 Probe Info  		12.91  LDD1925  [24]
C265
 Probe Info  		14.32  LDD1936  [24]
C270
 Probe Info  		8.22  LDD1940  [24]
C273
 Probe Info  		5.06  LDD1943  [24]
C280
 Probe Info  		12.73  LDD1950  [24]
C282
 Probe Info  		21.71  LDD1952  [24]
C293
 Probe Info  		22.47  LDD1963  [24]
C339
 Probe Info  		6.96  LDD2002  [24]
C348
 Probe Info  		11.00  LDD2009  [24]
C350
 Probe Info  		22.78  LDD2011  [24]
C353
 Probe Info  		12.91  LDD2014  [24]
C361
 Probe Info  		20.11  LDD2022  [24]
C376
 Probe Info  		6.59  LDD2036  [24]
C382
 Probe Info  		48.50  LDD2041  [24]
C403
 Probe Info  		16.80  LDD2061  [24]
C426
 Probe Info  		13.83  LDD2081  [24]
FFF probe11
 Probe Info  		10.33  LDD0471  [25]
FFF probe13
 Probe Info  		9.09  LDD0475  [25]
FFF probe15
 Probe Info  		5.07  LDD0478  [25]
FFF probe2
 Probe Info  		5.94  LDD0479  [25]
FFF probe4
 Probe Info  		9.77  LDD0466  [25]
FFF probe7
 Probe Info  		20.00  LDD0483  [25]
JN0003
 Probe Info  		20.00  LDD0469  [25]
STS-2
 Probe Info  		1.59  LDD0139  [26]
VE-P
 Probe Info  		N.A.  LDD0396  [27]
Kambe_26
 Probe Info  		12.54  LDD0127  [28]
BD-F
 Probe Info  		Y384(0.00); A378(0.00)  LDD0024  [29]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C543(0.62)  LDD2142  [4]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C543(0.89)  LDD2112  [4]
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C147(0.51); C543(0.48)  LDD2095  [4]
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C147(1.01); C543(0.85)  LDD2130  [4]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C147(0.63)  LDD2117  [4]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C147(1.02); C543(2.28)  LDD2152  [4]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C543(0.56)  LDD2132  [4]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C147(0.83); C543(0.52)  LDD2131  [4]
 LDCM0214  AC1 HEK-293T C147(0.93)  LDD0812  [30]
 LDCM0215  AC10 PaTu 8988t C200(1.40)  LDD1094  [30]
 LDCM0226  AC11 PaTu 8988t C200(1.12)  LDD1105  [30]
 LDCM0230  AC113 PaTu 8988t C200(1.16)  LDD1109  [30]
 LDCM0231  AC114 PaTu 8988t C200(0.76)  LDD1110  [30]
 LDCM0232  AC115 PaTu 8988t C200(0.75)  LDD1111  [30]
 LDCM0233  AC116 PaTu 8988t C200(0.76)  LDD1112  [30]
 LDCM0234  AC117 PaTu 8988t C200(1.43)  LDD1113  [30]
 LDCM0235  AC118 PaTu 8988t C200(1.14)  LDD1114  [30]
 LDCM0236  AC119 PaTu 8988t C200(0.85)  LDD1115  [30]
 LDCM0237  AC12 PaTu 8988t C200(0.84)  LDD1116  [30]
 LDCM0238  AC120 PaTu 8988t C200(1.20)  LDD1117  [30]
 LDCM0239  AC121 PaTu 8988t C200(0.62)  LDD1118  [30]
 LDCM0240  AC122 PaTu 8988t C200(0.93)  LDD1119  [30]
 LDCM0241  AC123 PaTu 8988t C200(0.71)  LDD1120  [30]
 LDCM0242  AC124 PaTu 8988t C200(0.72)  LDD1121  [30]
 LDCM0243  AC125 PaTu 8988t C200(1.14)  LDD1122  [30]
 LDCM0244  AC126 PaTu 8988t C200(0.78)  LDD1123  [30]
 LDCM0245  AC127 PaTu 8988t C200(0.67)  LDD1124  [30]
 LDCM0259  AC14 PaTu 8988t C200(1.12)  LDD1138  [30]
 LDCM0270  AC15 PaTu 8988t C200(1.18)  LDD1149  [30]
 LDCM0276  AC17 HEK-293T C147(1.25)  LDD0874  [30]
 LDCM0277  AC18 HEK-293T C147(1.02)  LDD0875  [30]
 LDCM0278  AC19 HEK-293T C147(0.99)  LDD0876  [30]
 LDCM0279  AC2 HEK-293T C147(1.26)  LDD0877  [30]
 LDCM0280  AC20 HEK-293T C147(1.13)  LDD0878  [30]
 LDCM0281  AC21 HEK-293T C147(1.25)  LDD0879  [30]
 LDCM0282  AC22 HEK-293T C147(1.26)  LDD0880  [30]
 LDCM0283  AC23 HEK-293T C147(1.36)  LDD0881  [30]
 LDCM0284  AC24 HEK-293T C147(1.07)  LDD0882  [30]
 LDCM0285  AC25 HEK-293T C26(0.98); C147(0.94); C469(1.07); C200(0.99)  LDD1524  [31]
 LDCM0286  AC26 HEK-293T C26(1.08); C147(1.01); C543(1.00); C469(1.07)  LDD1525  [31]
 LDCM0287  AC27 HEK-293T C26(0.98); C147(1.02); C543(0.81); C469(1.04)  LDD1526  [31]
 LDCM0288  AC28 HEK-293T C26(1.02); C147(0.96); C543(0.86); C469(1.09)  LDD1527  [31]
 LDCM0289  AC29 HEK-293T C26(1.04); C147(1.01); C543(1.08); C469(1.03)  LDD1528  [31]
 LDCM0290  AC3 HEK-293T C147(1.06)  LDD0888  [30]
 LDCM0291  AC30 HEK-293T C26(1.01); C147(0.97); C543(1.02); C469(1.08)  LDD1530  [31]
 LDCM0292  AC31 HEK-293T C26(1.03); C147(0.97); C543(0.90); C469(1.14)  LDD1531  [31]
 LDCM0293  AC32 HEK-293T C26(1.04); C147(0.98); C543(1.07); C469(1.01)  LDD1532  [31]
 LDCM0294  AC33 HEK-293T C26(1.00); C147(1.02); C469(1.06); C200(1.00)  LDD1533  [31]
 LDCM0295  AC34 HEK-293T C26(1.05); C147(0.99); C543(1.11); C469(1.14)  LDD1534  [31]
 LDCM0296  AC35 HEK-293T C26(0.99); C147(0.98); C543(1.12); C469(1.04)  LDD1535  [31]
 LDCM0297  AC36 HEK-293T C26(1.01); C147(0.94); C543(0.91); C469(1.03)  LDD1536  [31]
 LDCM0298  AC37 HEK-293T C26(1.12); C147(0.99); C543(1.12); C469(1.06)  LDD1537  [31]
 LDCM0299  AC38 HEK-293T C26(1.07); C147(1.03); C543(0.92); C469(1.10)  LDD1538  [31]
 LDCM0300  AC39 HEK-293T C26(1.04); C147(1.03); C543(0.84); C469(1.06)  LDD1539  [31]
 LDCM0301  AC4 HEK-293T C147(1.33)  LDD0899  [30]
 LDCM0302  AC40 HEK-293T C26(1.04); C147(0.99); C543(1.08); C469(1.00)  LDD1541  [31]
 LDCM0303  AC41 HEK-293T C26(1.03); C147(1.07); C469(1.02); C200(0.96)  LDD1542  [31]
 LDCM0304  AC42 HEK-293T C26(0.99); C147(0.93); C543(1.34); C469(1.14)  LDD1543  [31]
 LDCM0305  AC43 HEK-293T C26(1.04); C147(0.98); C543(1.24); C469(1.00)  LDD1544  [31]
 LDCM0306  AC44 HEK-293T C26(1.03); C147(0.94); C543(1.20); C469(1.06)  LDD1545  [31]
 LDCM0307  AC45 HEK-293T C26(1.07); C147(1.01); C543(0.89); C469(1.09)  LDD1546  [31]
 LDCM0308  AC46 HEK-293T C147(0.80)  LDD0906  [30]
 LDCM0309  AC47 HEK-293T C147(1.08)  LDD0907  [30]
 LDCM0310  AC48 HEK-293T C147(0.98)  LDD0908  [30]
 LDCM0311  AC49 HEK-293T C147(1.21)  LDD0909  [30]
 LDCM0312  AC5 HEK-293T C147(1.14)  LDD0910  [30]
 LDCM0313  AC50 HEK-293T C147(0.88)  LDD0911  [30]
 LDCM0314  AC51 HEK-293T C147(0.90)  LDD0912  [30]
 LDCM0315  AC52 HEK-293T C147(0.93)  LDD0913  [30]
 LDCM0316  AC53 HEK-293T C147(0.73)  LDD0914  [30]
 LDCM0317  AC54 HEK-293T C147(1.03)  LDD0915  [30]
 LDCM0318  AC55 HEK-293T C147(1.08)  LDD0916  [30]
 LDCM0319  AC56 HEK-293T C147(0.92)  LDD0917  [30]
 LDCM0320  AC57 HEK-293T C147(1.22)  LDD0918  [30]
 LDCM0321  AC58 HEK-293T C147(1.00)  LDD0919  [30]
 LDCM0322  AC59 HEK-293T C147(0.97)  LDD0920  [30]
 LDCM0323  AC6 PaTu 8988t C200(1.01)  LDD1202  [30]
 LDCM0324  AC60 HEK-293T C147(0.93)  LDD0922  [30]
 LDCM0325  AC61 HEK-293T C147(1.05)  LDD0923  [30]
 LDCM0326  AC62 HEK-293T C147(0.92)  LDD0924  [30]
 LDCM0327  AC63 HEK-293T C147(0.99)  LDD0925  [30]
 LDCM0328  AC64 HEK-293T C147(0.88)  LDD0926  [30]
 LDCM0329  AC65 HEK-293T C147(1.02)  LDD0927  [30]
 LDCM0330  AC66 HEK-293T C147(0.84)  LDD0928  [30]
 LDCM0331  AC67 HEK-293T C147(0.93)  LDD0929  [30]
 LDCM0334  AC7 PaTu 8988t C200(0.78)  LDD1213  [30]
 LDCM0345  AC8 PaTu 8988t C200(0.77)  LDD1224  [30]
 LDCM0545  Acetamide MDA-MB-231 C147(0.52)  LDD2138  [4]
 LDCM0520  AKOS000195272 MDA-MB-231 C147(0.83)  LDD2113  [4]
 LDCM0248  AKOS034007472 PaTu 8988t C200(1.34)  LDD1127  [30]
 LDCM0356  AKOS034007680 PaTu 8988t C200(1.09)  LDD1235  [30]
 LDCM0275  AKOS034007705 PaTu 8988t C200(1.28)  LDD1154  [30]
 LDCM0020  ARS-1620 HCC44 C26(1.23); C136(1.16); C141(1.16)  LDD2171  [30]
 LDCM0498  BS-3668 MDA-MB-231 C147(0.59)  LDD2091  [4]
 LDCM0108  Chloroacetamide HeLa C8(0.00); C17(0.00)  LDD0222  [21]
 LDCM0367  CL1 HEK-293T C26(1.01); C147(1.05); C543(0.84); C469(1.00)  LDD1571  [31]
 LDCM0368  CL10 HEK-293T C26(0.96); C147(1.48); C543(0.71); C469(1.15)  LDD1572  [31]
 LDCM0369  CL100 HEK-293T C147(1.27)  LDD0967  [30]
 LDCM0370  CL101 PaTu 8988t C200(1.25)  LDD1249  [30]
 LDCM0371  CL102 PaTu 8988t C200(0.94)  LDD1250  [30]
 LDCM0372  CL103 PaTu 8988t C200(0.88)  LDD1251  [30]
 LDCM0373  CL104 PaTu 8988t C200(1.15)  LDD1252  [30]
 LDCM0374  CL105 HEK-293T C147(0.96)  LDD0972  [30]
 LDCM0375  CL106 HEK-293T C147(1.18)  LDD0973  [30]
 LDCM0376  CL107 HEK-293T C147(1.04)  LDD0974  [30]
 LDCM0377  CL108 HEK-293T C147(1.21)  LDD0975  [30]
 LDCM0378  CL109 HEK-293T C147(1.01)  LDD0976  [30]
 LDCM0379  CL11 HEK-293T C26(1.00); C147(1.15); C543(1.06); C469(1.03)  LDD1583  [31]
 LDCM0380  CL110 HEK-293T C147(1.05)  LDD0978  [30]
 LDCM0381  CL111 HEK-293T C147(0.95)  LDD0979  [30]
 LDCM0382  CL112 HEK-293T C26(1.07); C147(1.03); C469(1.02); C200(0.99)  LDD1586  [31]
 LDCM0383  CL113 HEK-293T C26(1.11); C147(0.96); C543(0.97); C469(1.00)  LDD1587  [31]
 LDCM0384  CL114 HEK-293T C26(1.06); C147(1.05); C469(1.01); C200(1.44)  LDD1588  [31]
 LDCM0385  CL115 HEK-293T C26(0.96); C147(0.85); C543(0.91); C469(0.99)  LDD1589  [31]
 LDCM0386  CL116 HEK-293T C26(1.07); C147(1.01); C469(1.04); C200(1.04)  LDD1590  [31]
 LDCM0387  CL117 HEK-293T C26(1.08); C147(0.99); C543(1.06); C469(1.01)  LDD1591  [31]
 LDCM0388  CL118 HEK-293T C26(1.05); C147(1.01); C469(0.86); C200(1.00)  LDD1592  [31]
 LDCM0389  CL119 HEK-293T C26(0.96); C147(0.89); C543(0.94); C469(0.98)  LDD1593  [31]
 LDCM0390  CL12 HEK-293T C26(0.99); C147(1.05); C543(0.98); C469(0.98)  LDD1594  [31]
 LDCM0391  CL120 HEK-293T C26(1.10); C147(1.02); C469(1.02); C200(0.92)  LDD1595  [31]
 LDCM0392  CL121 HEK-293T C147(0.92)  LDD0990  [30]
 LDCM0393  CL122 HEK-293T C147(1.06)  LDD0991  [30]
 LDCM0394  CL123 HEK-293T C147(0.98)  LDD0992  [30]
 LDCM0395  CL124 HEK-293T C147(1.01)  LDD0993  [30]
 LDCM0396  CL125 HEK-293T C147(1.07)  LDD0994  [30]
 LDCM0397  CL126 HEK-293T C147(1.10)  LDD0995  [30]
 LDCM0398  CL127 HEK-293T C147(1.08)  LDD0996  [30]
 LDCM0399  CL128 HEK-293T C147(1.07)  LDD0997  [30]
 LDCM0400  CL13 HEK-293T C26(0.99); C147(0.94); C543(1.27); C469(1.03)  LDD1604  [31]
 LDCM0401  CL14 HEK-293T C26(0.91); C147(0.95); C469(1.03); C200(0.95)  LDD1605  [31]
 LDCM0402  CL15 HEK-293T C26(0.72); C147(1.00); C543(1.30); C469(1.10)  LDD1606  [31]
 LDCM0403  CL16 HEK-293T C147(1.02)  LDD1001  [30]
 LDCM0404  CL17 HEK-293T C147(1.03)  LDD1002  [30]
 LDCM0405  CL18 HEK-293T C147(0.97)  LDD1003  [30]
 LDCM0406  CL19 HEK-293T C147(1.14)  LDD1004  [30]
 LDCM0407  CL2 HEK-293T C26(0.97); C147(0.98); C469(0.95); C200(0.93)  LDD1611  [31]
 LDCM0408  CL20 HEK-293T C147(0.94)  LDD1006  [30]
 LDCM0409  CL21 HEK-293T C147(1.18)  LDD1007  [30]
 LDCM0410  CL22 HEK-293T C147(1.09)  LDD1008  [30]
 LDCM0411  CL23 HEK-293T C147(1.04)  LDD1009  [30]
 LDCM0412  CL24 HEK-293T C147(0.96)  LDD1010  [30]
 LDCM0413  CL25 HEK-293T C147(0.96)  LDD1011  [30]
 LDCM0414  CL26 HEK-293T C147(0.96)  LDD1012  [30]
 LDCM0415  CL27 HEK-293T C147(1.23)  LDD1013  [30]
 LDCM0416  CL28 HEK-293T C147(1.19)  LDD1014  [30]
 LDCM0417  CL29 HEK-293T C147(1.07)  LDD1015  [30]
 LDCM0418  CL3 HEK-293T C26(0.88); C147(0.89); C543(1.33); C469(1.08)  LDD1622  [31]
 LDCM0419  CL30 HEK-293T C147(1.13)  LDD1017  [30]
 LDCM0420  CL31 HEK-293T C26(0.99); C147(1.01); C543(1.41); C469(1.05)  LDD1624  [31]
 LDCM0421  CL32 HEK-293T C26(1.06); C147(1.02); C543(1.16); C469(0.99)  LDD1625  [31]
 LDCM0422  CL33 HEK-293T C26(1.14); C147(1.35); C543(1.32); C469(1.19)  LDD1626  [31]
 LDCM0423  CL34 HEK-293T C26(1.12); C147(1.20); C543(1.03); C469(0.98)  LDD1627  [31]
 LDCM0424  CL35 HEK-293T C26(1.16); C147(0.99); C543(1.10); C469(1.04)  LDD1628  [31]
 LDCM0425  CL36 HEK-293T C26(1.03); C147(1.01); C543(1.00); C469(1.05)  LDD1629  [31]
 LDCM0426  CL37 HEK-293T C26(1.00); C147(0.93); C543(1.17); C469(0.99)  LDD1630  [31]
 LDCM0428  CL39 HEK-293T C26(0.75); C147(0.90); C543(1.07); C469(0.94)  LDD1632  [31]
 LDCM0429  CL4 HEK-293T C26(1.07); C147(1.09); C469(1.08); C200(1.29)  LDD1633  [31]
 LDCM0430  CL40 HEK-293T C26(1.04); C147(0.93); C469(1.06); C200(0.94)  LDD1634  [31]
 LDCM0431  CL41 HEK-293T C26(0.99); C147(1.06); C469(0.98); C200(1.30)  LDD1635  [31]
 LDCM0432  CL42 HEK-293T C26(1.04); C147(0.94); C543(1.50); C469(0.69)  LDD1636  [31]
 LDCM0433  CL43 HEK-293T C26(1.01); C147(1.03); C543(1.09); C469(1.00)  LDD1637  [31]
 LDCM0434  CL44 HEK-293T C26(1.08); C147(1.03); C543(1.22); C469(0.98)  LDD1638  [31]
 LDCM0435  CL45 HEK-293T C26(0.98); C147(1.27); C543(1.11); C469(1.06)  LDD1639  [31]
 LDCM0436  CL46 HEK-293T C147(1.05)  LDD1034  [30]
 LDCM0437  CL47 HEK-293T C147(1.07)  LDD1035  [30]
 LDCM0438  CL48 HEK-293T C147(1.07)  LDD1036  [30]
 LDCM0439  CL49 HEK-293T C147(1.09)  LDD1037  [30]
 LDCM0440  CL5 HEK-293T C26(0.98); C147(1.10); C469(1.12); C200(1.07)  LDD1644  [31]
 LDCM0441  CL50 HEK-293T C147(1.35)  LDD1039  [30]
 LDCM0442  CL51 HEK-293T C147(1.30)  LDD1040  [30]
 LDCM0443  CL52 HEK-293T C147(0.92)  LDD1041  [30]
 LDCM0444  CL53 HEK-293T C147(1.03)  LDD1042  [30]
 LDCM0445  CL54 HEK-293T C147(1.27)  LDD1043  [30]
 LDCM0446  CL55 HEK-293T C147(1.21)  LDD1044  [30]
 LDCM0447  CL56 HEK-293T C147(1.00)  LDD1045  [30]
 LDCM0448  CL57 HEK-293T C147(1.14)  LDD1046  [30]
 LDCM0449  CL58 HEK-293T C147(1.20)  LDD1047  [30]
 LDCM0450  CL59 HEK-293T C147(1.23)  LDD1048  [30]
 LDCM0451  CL6 HEK-293T C26(0.95); C147(1.06); C543(1.59); C469(0.94)  LDD1654  [31]
 LDCM0452  CL60 HEK-293T C147(1.28)  LDD1050  [30]
 LDCM0453  CL61 HEK-293T C147(0.83)  LDD1051  [30]
 LDCM0454  CL62 HEK-293T C147(0.96)  LDD1052  [30]
 LDCM0455  CL63 HEK-293T C147(1.28)  LDD1053  [30]
 LDCM0456  CL64 HEK-293T C147(0.87)  LDD1054  [30]
 LDCM0457  CL65 HEK-293T C147(1.28)  LDD1055  [30]
 LDCM0458  CL66 HEK-293T C147(1.07)  LDD1056  [30]
 LDCM0459  CL67 HEK-293T C147(1.09)  LDD1057  [30]
 LDCM0460  CL68 HEK-293T C147(1.12)  LDD1058  [30]
 LDCM0461  CL69 HEK-293T C147(0.94)  LDD1059  [30]
 LDCM0462  CL7 HEK-293T C26(0.96); C147(1.05); C543(1.75); C469(1.11)  LDD1665  [31]
 LDCM0463  CL70 HEK-293T C147(0.97)  LDD1061  [30]
 LDCM0464  CL71 HEK-293T C147(1.12)  LDD1062  [30]
 LDCM0465  CL72 HEK-293T C147(1.00)  LDD1063  [30]
 LDCM0466  CL73 HEK-293T C147(0.92)  LDD1064  [30]
 LDCM0467  CL74 HEK-293T C147(1.35)  LDD1065  [30]
 LDCM0469  CL76 HEK-293T C147(0.93)  LDD1067  [30]
 LDCM0470  CL77 HEK-293T C147(1.17)  LDD1068  [30]
 LDCM0471  CL78 HEK-293T C147(0.72)  LDD1069  [30]
 LDCM0472  CL79 HEK-293T C147(0.85)  LDD1070  [30]
 LDCM0473  CL8 HEK-293T C26(0.90); C147(1.66); C543(2.18); C469(1.31)  LDD1676  [31]
 LDCM0474  CL80 HEK-293T C147(0.94)  LDD1072  [30]
 LDCM0475  CL81 HEK-293T C147(0.93)  LDD1073  [30]
 LDCM0476  CL82 HEK-293T C147(1.13)  LDD1074  [30]
 LDCM0477  CL83 HEK-293T C147(1.19)  LDD1075  [30]
 LDCM0478  CL84 HEK-293T C147(0.85)  LDD1076  [30]
 LDCM0479  CL85 HEK-293T C147(0.86)  LDD1077  [30]
 LDCM0480  CL86 HEK-293T C147(0.77)  LDD1078  [30]
 LDCM0481  CL87 HEK-293T C147(0.88)  LDD1079  [30]
 LDCM0482  CL88 HEK-293T C147(0.87)  LDD1080  [30]
 LDCM0483  CL89 HEK-293T C147(0.92)  LDD1081  [30]
 LDCM0484  CL9 HEK-293T C26(1.14); C147(1.14); C543(1.18); C469(1.17)  LDD1687  [31]
 LDCM0485  CL90 HEK-293T C147(1.19)  LDD1083  [30]
 LDCM0486  CL91 HEK-293T C147(0.93)  LDD1084  [30]
 LDCM0487  CL92 HEK-293T C147(1.30)  LDD1085  [30]
 LDCM0488  CL93 HEK-293T C147(0.97)  LDD1086  [30]
 LDCM0489  CL94 HEK-293T C147(1.12)  LDD1087  [30]
 LDCM0490  CL95 HEK-293T C147(1.21)  LDD1088  [30]
 LDCM0491  CL96 HEK-293T C147(1.17)  LDD1089  [30]
 LDCM0492  CL97 HEK-293T C147(1.13)  LDD1090  [30]
 LDCM0493  CL98 HEK-293T C147(1.14)  LDD1091  [30]
 LDCM0494  CL99 HEK-293T C147(1.20)  LDD1092  [30]
 LDCM0185  Compound 17 HEK-293T 7.49  LDD0504  [25]
 LDCM0184  Compound 20 HEK-293T 15.38  LDD0503  [25]
 LDCM0186  Compound 31 HEK-293T 3.29  LDD0506  [25]
 LDCM0187  Compound 32 HEK-293T 16.67  LDD0507  [25]
 LDCM0188  Compound 33 HEK-293T 7.07  LDD0505  [25]
 LDCM0495  E2913 HEK-293T C26(0.77); C147(0.81); C543(1.02); C469(0.97)  LDD1698  [31]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C543(2.41)  LDD1702  [4]
 LDCM0625  F8 Ramos C147(0.99)  LDD2187  [32]
 LDCM0572  Fragment10 Ramos C147(0.46)  LDD2189  [32]
 LDCM0573  Fragment11 Ramos C147(1.20); C26(5.10)  LDD2190  [32]
 LDCM0574  Fragment12 Ramos C147(0.50)  LDD2191  [32]
 LDCM0575  Fragment13 Ramos C147(0.90); C26(0.89)  LDD2192  [32]
 LDCM0576  Fragment14 Ramos C147(0.72)  LDD2193  [32]
 LDCM0579  Fragment20 Ramos C147(0.40)  LDD2194  [32]
 LDCM0580  Fragment21 Ramos C147(0.88); C26(1.02)  LDD2195  [32]
 LDCM0582  Fragment23 Ramos C147(1.00)  LDD2196  [32]
 LDCM0578  Fragment27 Ramos C147(0.89); C26(1.09)  LDD2197  [32]
 LDCM0586  Fragment28 Ramos C147(0.63); C26(0.92)  LDD2198  [32]
 LDCM0588  Fragment30 Ramos C147(1.13); C26(1.54)  LDD2199  [32]
 LDCM0589  Fragment31 Ramos C147(1.25); C26(1.05)  LDD2200  [32]
 LDCM0590  Fragment32 Ramos C147(0.54)  LDD2201  [32]
 LDCM0468  Fragment33 HEK-293T C147(1.20)  LDD1066  [30]
 LDCM0596  Fragment38 Ramos C147(0.82); C26(1.25)  LDD2203  [32]
 LDCM0566  Fragment4 Ramos C147(0.82)  LDD2184  [32]
 LDCM0427  Fragment51 HEK-293T C26(0.90); C147(0.94); C469(0.91); C200(0.97)  LDD1631  [31]
 LDCM0610  Fragment52 Ramos C147(1.20); C26(1.35)  LDD2204  [32]
 LDCM0614  Fragment56 Ramos C147(1.32)  LDD2205  [32]
 LDCM0569  Fragment7 Ramos C147(0.65)  LDD2186  [32]
 LDCM0571  Fragment9 Ramos C147(0.42)  LDD2188  [32]
 LDCM0116  HHS-0101 DM93 Y384(0.79); Y379(0.86); Y233(0.98)  LDD0264  [8]
 LDCM0117  HHS-0201 DM93 Y379(1.02); Y384(1.04); Y233(1.87)  LDD0265  [8]
 LDCM0118  HHS-0301 DM93 Y379(0.56); Y384(0.91)  LDD0266  [8]
 LDCM0119  HHS-0401 DM93 Y384(1.28); Y379(1.73); Y233(2.19)  LDD0267  [8]
 LDCM0120  HHS-0701 DM93 Y384(6.94); Y379(13.11)  LDD0268  [8]
 LDCM0107  IAA HeLa C8(0.00); C147(0.00)  LDD0221  [21]
 LDCM0179  JZ128 PC-3 N.A.  LDD0462  [7]
 LDCM0073  Kambe_cp3 PC-3 12.54  LDD0127  [28]
 LDCM0022  KB02 HEK-293T C26(0.93); C136(1.00); C141(0.77); C147(0.99)  LDD1492  [31]
 LDCM0023  KB03 HEK-293T C26(0.95); C136(1.01); C141(0.85); C147(1.00)  LDD1497  [31]
 LDCM0024  KB05 G361 C147(0.82)  LDD3311  [6]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C147(0.64)  LDD2121  [4]
 LDCM0109  NEM HeLa N.A.  LDD0224  [21]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C147(0.90)  LDD2090  [4]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C543(0.81)  LDD2100  [4]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C543(0.58)  LDD2106  [4]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C147(0.85); C543(1.16)  LDD2107  [4]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C543(1.88)  LDD2108  [4]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C543(0.55)  LDD2109  [4]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C543(1.16)  LDD2111  [4]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C543(0.40)  LDD2115  [4]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C147(0.72)  LDD2120  [4]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C543(1.28)  LDD2122  [4]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C147(0.81)  LDD2123  [4]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C543(0.90)  LDD2124  [4]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C147(0.76); C543(0.87)  LDD2125  [4]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C543(0.79)  LDD2126  [4]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C147(0.95); C543(0.54)  LDD2127  [4]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C543(1.44)  LDD2129  [4]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C147(0.76); C543(0.41)  LDD2133  [4]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C147(0.40)  LDD2134  [4]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C147(1.19)  LDD2135  [4]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C147(1.01); C543(0.91)  LDD2136  [4]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C543(1.15)  LDD2137  [4]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C147(0.72); C8(1.05)  LDD2140  [4]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C543(1.06)  LDD2141  [4]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C543(0.71)  LDD2145  [4]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C147(0.80); C543(0.91)  LDD2146  [4]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C147(0.49)  LDD2148  [4]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C543(1.36)  LDD2149  [4]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C147(0.51); C543(0.53)  LDD2150  [4]
 LDCM0131  RA190 MM1.R C147(0.96)  LDD0304  [33]
 LDCM0021  THZ1 HeLa S3 C275(0.96)  LDD0460  [7]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
TERF1-interacting nuclear factor 2 (TINF2) . Q9BSI4

The Drug(s) Related To This Target

Approved
Click To Hide/Show 2 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Bestatin Small molecular drug D0RA5Q
Captopril Small molecular drug DB01197
Phase 1
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Acebilustat . D07VNH
Investigative
Click To Hide/Show 76 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
(2s)-2-amino-5-oxo-5-[(4-phenylmethoxyphenyl)Amino]Pentanoic Acid Small molecular drug DB07102
(4-(Thiophen-2-yl)Phenyl)Methanamine Small molecular drug D0I4OV
(4-fluorophenyl)(Pyridin-4-yl)Methanone Small molecular drug D0J0WO
(R)-2-((4-benzylphenoxy)Methyl)Piperidine Small molecular drug D0C1XE
(R)-2-((4-phenoxyphenoxy)Methyl)Piperidine Small molecular drug D00FDS
(R)-2-(4-benzylphenoxymethyl)Pyrrolidine Small molecular drug D06SMN
(R)-n-benzyl-4-(Pyrrolidin-2-ylmethoxy)Aniline Small molecular drug D01RVF
(R/S)-2-((4-benzylphenoxy)Methyl)Piperazine Small molecular drug D0H9NZ
(R/S)-2-((4-benzylphenoxy)Methyl)Piperidine Small molecular drug D07ZJS
(R/S)-2-((4-phenoxyphenoxy)Methyl)Piperidine Small molecular drug D00TNN
(S)-2-((4-phenoxyphenoxy)Methyl)Piperidine Small molecular drug D05NXQ
1-(2,2'-bithiophen-5-yl)Methanamine Small molecular drug D0R7BT
1-(22'-bithiophen-5-yl)Methanamine Small molecular drug DB07094
1-(4-phenoxyphenyl)Piperazine Small molecular drug D0V0MH
1-(4-thiophen-2-ylphenyl)Methanamine Small molecular drug DB07259
1-(Pentyloxy)-4-phenoxybenzene Small molecular drug D07LTR
1-butoxy-4-phenoxybenzene Small molecular drug D07TVA
1-[4-(4-iodophenoxy)Phenyl]Piperazine Small molecular drug D0P7DF
1-[4-(Benzothiazol-2-yloxy)Benzyl]Piperidin-4-ol Small molecular drug D09BWE
2-(4-benzylphenoxy)Ethanamine Small molecular drug D0W2OP
2-(4-phenoxyphenoxy)Ethanamine Small molecular drug D02AYI
2-(4-piperidin-1-ylmethylphenoxy)Benzothiazole Small molecular drug D0PF9Q
2-(7-(Benzyloxy)-1h-indol-3-yl)Ethanamine Small molecular drug D0C8MT
2-amino-n-[4-(Phenylmethoxy)Phenyl]-acetamide Small molecular drug D06RWH
2-[4-(2-azepan-1-ylethoxy)Phenoxy]Benzooxazole Small molecular drug D03GON
2-[4-(2-azepan-1-ylethoxy)Phenoxy]Benzothiazole Small molecular drug D08UIO
2-[4-(2-morpholin-4-ylethoxy)Phenoxy]Benzooxazole Small molecular drug D09PGC
2-[4-(2-piperidin-1-ylethyl)Phenoxy]Benzothiazole Small molecular drug D0Q8LS
3-(Benzyloxy)Pyridin-2-amine Small molecular drug D09DRF
4-(2-amino-1,3-thiazol-4-yl)Phenol Small molecular drug D01KOI
4-(2-amino-13-thiazol-4-yl)Phenol Small molecular drug DB07292
4-(4-(Pentyloxy)Phenoxy)Phenol Small molecular drug D0I7MC
4-(4-butoxyphenoxy)Phenol Small molecular drug D01QWO
4-(4-propoxyphenoxy)Phenol Small molecular drug D0Y6IV
4-amino-n-[4-(Benzyloxy)Phenyl]Butanamide Small molecular drug D09MDO
4-[2-(4-benzylphenoxy)Ethyl]Pyridine Small molecular drug D0VN8V
4s-4,5-diamino-n-(4-phenoxyphenyl)Pentanamide Small molecular drug D0M2CY
5-[2-(1h-pyrrol-1-yl)Ethoxy]-1h-indole Small molecular drug D00YCG
5-[2-(4-hydroxyphenyl)Ethyl]Benzene-1,3-diol Small molecular drug D00TWK
5-[2-(4-hydroxyphenyl)Ethyl]Benzene-13-diol Small molecular drug DB08466
8(S)-amino-2(R)-methyl-7-oxononanoic Acid Small molecular drug D0SZ9E
Acetate Ion Small molecular drug D0F2ME
Jnj-10392980 Small molecular drug D00UIN
Kelatorphan Small molecular drug DB08040
N-(Pyridin-3-ylmethyl)Aniline Small molecular drug D0G0JC
N-benzyl-4-[(2r)-pyrrolidin-2-ylmethoxy]Aniline Small molecular drug DB07260
N-methyl-1-(2-thiophen-2-ylphenyl)Methanamine Small molecular drug D0A2YG
N-[4-(Benzyloxy)Phenyl]Glycinamide Small molecular drug DB07099
N1-[4-(Phenylmethoxy)Phenyl]-d-aspartamine Small molecular drug D0U1UV
N1-[4-(Phenylmethoxy)Phenyl]-d-glutamine Small molecular drug D04DRM
N1-[4-(Phenylmethoxy)Phenyl]-l-aspartamine Small molecular drug D0LZ3O
N1-[4-(Phenylmethoxy)Phenyl]-l-glutamine Small molecular drug D0HA1K
N4-[4-(Phenylmethoxy)Phenyl]-l-aspartamine Small molecular drug D04ZLZ
N5-(4-phenoxyphenyl)-l-glutamine Small molecular drug D09OWF
N5-[(4-phenoxy)-3-pyridyl]-l-glutamamide Small molecular drug D02TMR
N5-[4-(1h-pyrrol-1-yl)Phenyl]-l-glutamamide Small molecular drug D08WZB
N5-[4-(2-methylphenoxy)Phenyl]-l-glutamamide Small molecular drug D07KBF
N5-[4-(2-oxo-3-phenylpropoxy)Phenyl]-l-glutamine Small molecular drug D0DI4I
N5-[4-(2-phenylethoxy)Phenyl]-l-glutamine Small molecular drug D0N6TC
N5-[4-(3-methylphenoxy)Phenyl]-l-glutamamide Small molecular drug D00FCJ
N5-[4-(3-phenylpropoxy)Phenyl]-l-glutamine Small molecular drug D01YJJ
N5-[4-(4-(3-furyl)Phenoxy)Phenyl]-l-glutamamide Small molecular drug D0B9UW
N5-[4-(4-methylphenoxy)Phenyl]-l-glutamamide Small molecular drug D0G8SW
N5-[4-(N-phenylamino)Phenyl]-l-glutamine Small molecular drug D0Z6DL
N5-[4-(Phenylmethoxy)Phenyl]-d-glutamine Small molecular drug D0U1EV
N5-[4-(Phenylmethoxy)Phenyl]-l-glutamamide Small molecular drug D04CZF
N5-[4-(Phenylmethoxy)Phenyl]-l-glutamine Small molecular drug D08TNQ
N5-[4-benzylphenyl]-l-glutamamide Small molecular drug D0U2AM
N6-[4-(4-methylphenoxy)Phenyl]-l-homoglutamine Small molecular drug D0B0DP
Sa-6541 Small molecular drug D03UIF
Tosedostat Small molecular drug DB11781
Ubenimex Small molecular drug DB03424
(R)-pyridin-4-yl[4-(2-pyrrolidin-1-ylethoxy)Phenyl]Methanol . DB07258
Imidazole . DB03366
N-[3-[(1-aminoethyl)(Hydroxy)Phosphoryl]-2-(11'-biphenyl-4-ylmethyl)Propanoyl]Alanine . DB02062
{4-[(2r)-pyrrolidin-2-ylmethoxy]Phenyl}(4-thiophen-3-ylphenyl)Methanone . DB07237
Discontinued
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Dg051 Small molecular drug D06XEL

References

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Mass spectrometry data entry: PXD028270
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Mass spectrometry data entry: PXD047840
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Mass spectrometry data entry: PXD042377
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Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD022279
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Mass spectrometry data entry: PXD039931
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Mass spectrometry data entry: PXD029255
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Mass spectrometry data entry: PXD001377 , PXD005252
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Mass spectrometry data entry: PXD038010
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Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD025652
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