Details of the Probe

General Information of Probe

Probe ID
LDPC0269
Probe Name
FFF probe15
Synonyms
SCHEMBL20400697;AKOS034063859;Z2866905816
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 313.35
Lipid-water partition coefficient (xlogp) 2.5
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C17H19N3O3
IUPAC Name
N-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(3-but-3-ynyldiazirin-3-yl)propanamide
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)NCCC2=CC3=C(C=C2)OCO3
InChI
InChI=1S/C17H19N3O3/c1-2-3-8-17(19-20-17)9-6-16(21)18-10-7-13-4-5-14-15(11-13)23-12-22-14/h1,4-5,11H,3,6-10,12H2,(H,18,21)
InChIKey
APKAAFWWERXLLZ-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

140 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 5.36  LDD0478 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 5.37  LDD0478 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 8.52  LDD0478 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 20.00  LDD0478 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 5.17  LDD0478 
Acyl-CoA (8-3)-desaturase (FADS1) LDTP00968 20.00  LDD0478 
Acyl-CoA 6-desaturase (FADS2) LDTP01699 20.00  LDD0478 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 9.03  LDD0478 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 5.15  LDD0478 
Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) LDTP03560 7.10  LDD0490 
Alpha-galactosidase A (GLA) LDTP02141 14.07  LDD0478 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 16.18  LDD0478 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 5.29  LDD0478 
Atlastin-2 (ATL2) LDTP09251 8.71  LDD0478 
Atlastin-3 (ATL3) LDTP07362 5.50  LDD0478 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 20.00  LDD0478 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 20.00  LDD0478 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 8.86  LDD0478 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 13.33  LDD0478 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 5.89  LDD0478 
Beta-galactosidase (GLB1) LDTP02837 9.67  LDD0478 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 13.81  LDD0478 
Beta-hexosaminidase subunit beta (HEXB) LDTP02216 5.30  LDD0478 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 6.31  LDD0478 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 9.60  LDD0478 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 20.00  LDD0478 
Catechol O-methyltransferase (COMT) LDTP03145 11.46  LDD0478 
Cathepsin B (CTSB) LDTP02223 8.66  LDD0478 
Cathepsin D (CTSD) LDTP02198 17.62  LDD0478 
Cell division cycle protein 27 homolog (CDC27) LDTP03525 5.50  LDD0478 
Complex I assembly factor ACAD9, mitochondrial (ACAD9) LDTP12048 14.66  LDD0478 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 5.05  LDD0478 
Cystathionine beta-synthase (CBS) LDTP03753 5.96  LDD0478 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 7.51  LDD0478 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 7.54  LDD0478 
Cytochrome b5 type B (CYB5B) LDTP00697 8.04  LDD0478 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 7.84  LDD0478 
Cytosolic purine 5'-nucleotidase (NT5C2) LDTP04327 5.66  LDD0478 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 11.41  LDD0478 
Delta(24)-sterol reductase (DHCR24) LDTP06375 8.78  LDD0478 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 12.80  LDD0478 
Dermcidin (DCD) LDTP05171 20.00  LDD0478 
Dihydrofolate reductase (DHFR) LDTP01769 20.00  LDD0478 
Dipeptidyl peptidase 1 (CTSC) LDTP04572 8.48  LDD0478 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 13.25  LDD0478 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 20.00  LDD0478 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 20.00  LDD0478 
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (ALG6) LDTP14213 7.62  LDD0478 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 7.16  LDD0478 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (STT3B) LDTP09388 6.39  LDD0478 
Dynamin-3 (DNM3) LDTP13744 5.49  LDD0478 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 12.13  LDD0478 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 19.11  LDD0478 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 20.00  LDD0478 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 11.97  LDD0478 
Epoxide hydrolase 1 (EPHX1) LDTP02175 16.57  LDD0490 
FAD synthase (FLAD1) LDTP09200 20.00  LDD0478 
Gamma-glutamyl hydrolase (GGH) LDTP09886 5.39  LDD0478 
Gamma-interferon-inducible lysosomal thiol reductase (IFI30) LDTP02651 20.00  LDD0478 
Glutamate dehydrogenase 1, mitochondrial (GLUD1) LDTP01768 7.88  LDD0478 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 6.75  LDD0478 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 15.65  LDD0478 
Helicase MOV-10 (MOV10) LDTP12233 9.84  LDD0478 
Heme oxygenase 1 (HMOX1) LDTP02359 20.00  LDD0490 
Heme oxygenase 2 (HMOX2) LDTP03540 20.00  LDD0478 
Histidine--tRNA ligase, cytoplasmic (HARS1) LDTP02602 16.55  LDD0478 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 5.68  LDD0478 
Holocytochrome c-type synthase (HCCS) LDTP04581 5.72  LDD0478 
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1) LDTP05301 12.12  LDD0478 
Insulin-degrading enzyme (IDE) LDTP02743 5.81  LDD0478 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 8.95  LDD0478 
Legumain (LGMN) LDTP10888 5.93  LDD0478 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 15.52  LDD0478 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 5.07  LDD0478 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 7.24  LDD0478 
Lysophosphatidylserine lipase ABHD12 (ABHD12) LDTP08799 10.83  LDD0478 
Lysophospholipid acyltransferase 5 (LPCAT3) LDTP07504 5.78  LDD0478 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 20.00  LDD0478 
Lysosomal alpha-glucosidase (GAA) LDTP02486 20.00  LDD0478 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 9.43  LDD0478 
Lysosomal protective protein (CTSA) LDTP02505 20.00  LDD0478 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 16.70  LDD0478 
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) LDTP02565 12.44  LDD0478 
Mitochondrial Rho GTPase 2 (RHOT2) LDTP08596 5.50  LDD0478 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 7.28  LDD0478 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 12.18  LDD0478 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 10.78  LDD0478 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 14.21  LDD0478 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 5.63  LDD0478 
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (NDUFS1) LDTP03433 12.38  LDD0478 
NADPH--cytochrome P450 reductase (POR) LDTP02848 6.45  LDD0478 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 14.16  LDD0478 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 20.00  LDD0478 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 18.75  LDD0478 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 12.73  LDD0478 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 16.58  LDD0478 
Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8) LDTP06104 6.40  LDD0478 
Peroxisomal leader peptide-processing protease (TYSND1) LDTP06720 8.32  LDD0478 
Peroxisomal trans-2-enoyl-CoA reductase (PECR) LDTP11437 6.80  LDD0478 
Phosphatidylinositol 4-kinase type 2-alpha (PI4K2A) LDTP11209 6.09  LDD0478 
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2) LDTP06638 20.00  LDD0478 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 9.15  LDD0478 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 20.00  LDD0478 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 20.00  LDD0478 
Presequence protease, mitochondrial (PITRM1) LDTP07003 5.58  LDD0478 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 16.59  LDD0478 
Prostaglandin reductase 2 (PTGR2) LDTP08979 13.12  LDD0490 
Prostaglandin reductase 3 (PTGR3) LDTP15422 20.00  LDD0478 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 6.56  LDD0478 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 10.88  LDD0478 
Proteasome subunit beta type-3 (PSMB3) LDTP04284 6.60  LDD0478 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 6.45  LDD0478 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 10.55  LDD0478 
Proteasome subunit beta type-7 (PSMB7) LDTP10862 5.39  LDD0478 
Protein O-GlcNAcase (OGA) LDTP00988 8.66  LDD0478 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 20.00  LDD0478 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 5.36  LDD0478 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 20.00  LDD0478 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 6.37  LDD0478 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 20.00  LDD0490 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 5.48  LDD0478 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 5.53  LDD0478 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 5.93  LDD0478 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 20.00  LDD0478 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 13.45  LDD0478 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 20.00  LDD0478 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 20.00  LDD0478 
Squalene synthase (FDFT1) LDTP03842 20.00  LDD0478 
Stearoyl-CoA desaturase (SCD) LDTP00344 20.00  LDD0478 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 6.77  LDD0478 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 14.22  LDD0490 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 9.89  LDD0478 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 5.05  LDD0478 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 10.47  LDD0478 
Tyrosine-protein kinase Yes (YES1) LDTP02231 12.10  LDD0478 
Ubiquitin carboxyl-terminal hydrolase 7 (USP7) LDTP09962 5.66  LDD0478 
Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 5.20  LDD0478 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 5.33  LDD0478 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 10.06  LDD0478 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 7.42  LDD0478 
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⏷ Show the Full List of 140 Enzyme
69 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 6.32  LDD0478 
Amyloid-beta precursor protein (APP) LDTP02071 5.05  LDD0478 
ATP synthase subunit gamma, mitochondrial (ATP5F1C) LDTP03810 5.80  LDD0478 
BOS complex subunit NCLN (NCLN) LDTP10036 9.66  LDD0478 
Calnexin (CANX) LDTP03405 5.08  LDD0478 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 11.18  LDD0478 
Derlin-1 (DERL1) LDTP11245 20.00  LDD0478 
EH domain-containing protein 1 (EHD1) LDTP11934 5.68  LDD0478 
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (SLC25A12) LDTP01301 14.24  LDD0478 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 11.84  LDD0478 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 20.00  LDD0478 
ER membrane protein complex subunit 1 (EMC1) LDTP08960 6.50  LDD0478 
Exocyst complex component 2 (EXOC2) LDTP10513 20.00  LDD0478 
Flotillin-1 (FLOT1) LDTP01366 20.00  LDD0478 
Hemoglobin subunit beta (HBB) LDTP05080 20.00  LDD0478 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 9.54  LDD0478 
Importin subunit alpha-1 (KPNA2) LDTP04501 12.09  LDD0478 
Importin-9 (IPO9) LDTP10663 5.25  LDD0478 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 7.46  LDD0478 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 11.48  LDD0478 
Metaxin-1 (MTX1) LDTP05900 20.00  LDD0478 
MICOS complex subunit MIC60 (IMMT) LDTP06660 6.42  LDD0478 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 20.00  LDD0478 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 6.58  LDD0478 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 7.71  LDD0478 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 18.32  LDD0478 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 20.00  LDD0478 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 20.00  LDD0478 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 9.14  LDD0478 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 15.74  LDD0478 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 6.52  LDD0478 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 20.00  LDD0478 
Mpv17-like protein 2 (MPV17L2) LDTP14952 16.59  LDD0478 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 20.00  LDD0478 
Nuclear pore complex protein Nup155 (NUP155) LDTP01295 12.13  LDD0490 
Nucleoporin NDC1 (NDC1) LDTP11213 12.94  LDD0478 
Oxysterol-binding protein-related protein 8 (OSBPL8) LDTP11531 7.76  LDD0478 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 5.37  LDD0478 
Prosaposin (PSAP) LDTP02215 20.00  LDD0478 
Protein GPR107 (GPR107) LDTP07236 20.00  LDD0478 
Protein SEC13 homolog (SEC13) LDTP04707 8.73  LDD0478 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 20.00  LDD0478 
Protein spinster homolog 1 (SPNS1) LDTP11844 17.00  LDD0478 
Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1) LDTP04932 7.63  LDD0478 
Protein tweety homolog 3 (TTYH3) LDTP11615 19.41  LDD0478 
Protein wntless homolog (WLS) LDTP07156 14.30  LDD0478 
Proton-activated chloride channel (PACC1) LDTP12042 8.84  LDD0478 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 13.21  LDD0478 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 14.16  LDD0478 
Sideroflexin-1 (SFXN1) LDTP12090 5.00  LDD0478 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 20.00  LDD0478 
Surfeit locus protein 4 (SURF4) LDTP00592 7.80  LDD0478 
Syntenin-1 (SDCBP) LDTP00310 11.63  LDD0478 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 15.85  LDD0478 
Translocation protein SEC63 homolog (SEC63) LDTP13243 6.35  LDD0478 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 17.36  LDD0478 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 5.11  LDD0478 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 5.79  LDD0478 
Transmembrane protein 126A (TMEM126A) LDTP15948 18.15  LDD0478 
Transmembrane protein 87A (TMEM87A) LDTP15481 17.69  LDD0478 
Transportin-1 (TNPO1) LDTP09949 12.50  LDD0490 
Transportin-2 (TNPO2) LDTP00434 10.74  LDD0478 
Tricarboxylate transport protein, mitochondrial (SLC25A1) LDTP04553 12.18  LDD0478 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 15.00  LDD0478 
V-type proton ATPase subunit B, brain isoform (ATP6V1B2) LDTP03104 12.93  LDD0478 
Vesicular integral-membrane protein VIP36 (LMAN2) LDTP05690 6.15  LDD0478 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 20.00  LDD0478 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 20.00  LDD0478 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 6.29  LDD0478 
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⏷ Show the Full List of 69 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Homeobox protein Meis1 (MEIS1) LDTP00286 18.19  LDD0478 
Homeobox protein Meis2 (MEIS2) LDTP00425 12.76  LDD0478 
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2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 5.55  LDD0478 
HLA class I histocompatibility antigen, C alpha chain (HLA-C) LDTP02491 13.86  LDD0478 
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58 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 5.79  LDD0490 
Alpha-centractin (ACTR1A) LDTP04904 20.00  LDD0478 
Amyloid beta precursor like protein 2 (APLP2) LDTP05491 10.71  LDD0478 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 13.10  LDD0478 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 20.00  LDD0478 
BRCA1-associated ATM activator 1 (BRAT1) LDTP07598 5.92  LDD0478 
Calumenin (CALU) LDTP00887 14.80  LDD0478 
Centrosomal protein 43 (CEP43) LDTP01652 14.88  LDD0478 
Clustered mitochondria protein homolog (CLUH) LDTP14486 20.00  LDD0478 
Desmocollin-1 (DSC1) LDTP05567 20.00  LDD0478 
Desmoglein-1 (DSG1) LDTP05353 20.00  LDD0478 
Dynactin subunit 2 (DCTN2) LDTP05922 5.70  LDD0478 
Dynactin subunit 4 (DCTN4) LDTP13402 6.11  LDD0478 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 20.00  LDD0478 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 20.00  LDD0490 
FAS-associated factor 2 (FAF2) LDTP10185 12.32  LDD0478 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 10.75  LDD0478 
HCLS1-associated protein X-1 (HAX1) LDTP00199 10.96  LDD0478 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 20.00  LDD0478 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 6.54  LDD0478 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 5.49  LDD0478 
Hornerin (HRNR) LDTP08425 20.00  LDD0478 
Junction plakoglobin (JUP) LDTP02756 5.88  LDD0478 
Keratinocyte proline-rich protein (KPRP) LDTP07136 20.00  LDD0478 
Kinetochore-associated protein 1 (KNTC1) LDTP04382 5.09  LDD0478 
Large proline-rich protein BAG6 (BAG6) LDTP04094 20.00  LDD0478 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 14.99  LDD0478 
Lipid droplet-regulating VLDL assembly factor AUP1 (AUP1) LDTP14217 7.84  LDD0478 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 20.00  LDD0478 
Mitochondrial import receptor subunit TOM70 (TOMM70) LDTP01432 5.33  LDD0478 
Neudesin (NENF) LDTP13630 14.07  LDD0478 
Nicastrin (NCSTN) LDTP09787 6.25  LDD0478 
Nucleobindin-1 (NUCB1) LDTP05375 20.00  LDD0478 
Nucleobindin-2 (NUCB2) LDTP05160 20.00  LDD0478 
Nucleolar complex protein 3 homolog (NOC3L) LDTP09545 11.79  LDD0478 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 7.28  LDD0478 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 7.59  LDD0478 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 20.00  LDD0478 
Protein FAM114A2 (FAM114A2) LDTP16080 9.91  LDD0478 
Protein TASOR (TASOR) LDTP13430 7.84  LDD0478 
Protein transport protein Sec16A (SEC16A) LDTP00512 13.55  LDD0478 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 20.00  LDD0478 
RAD50-interacting protein 1 (RINT1) LDTP07476 20.00  LDD0478 
Reticulocalbin-1 (RCN1) LDTP06352 20.00  LDD0478 
Reticulocalbin-2 (RCN2) LDTP06097 5.29  LDD0478 
Reticulon-4 (RTN4) LDTP12412 7.40  LDD0478 
Ribosome-binding protein 1 (RRBP1) LDTP13044 12.28  LDD0478 
Serpin B3 (SERPINB3) LDTP03493 20.00  LDD0478 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 13.23  LDD0478 
Small ribosomal subunit protein eS24 (RPS24) LDTP05012 9.09  LDD0478 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 13.35  LDD0478 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 6.01  LDD0478 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 20.00  LDD0478 
Transducin beta-like protein 2 (TBL2) LDTP16285 12.22  LDD0478 
Vacuolar protein sorting-associated protein 51 homolog (VPS51) LDTP13338 8.30  LDD0478 
Vimentin (VIM) LDTP02297 6.55  LDD0478 
WD repeat-containing protein 43 (WDR43) LDTP06305 7.47  LDD0478 
YLP motif-containing protein 1 (YLPM1) LDTP04290 5.33  LDD0478 
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⏷ Show the Full List of 58 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:200uM; negative probe:200uM
Quantitative Method
SILAC
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD0478 
Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:20uM; negative probe:20uM
Quantitative Method
SILAC
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD0490 
Download The Altas

References

1 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.