Details of the Probe

General Information of Probe

Probe ID
LDPC0017
Probe Name
PF-06672131
Synonyms
(E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(prop-2-yn-1-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide; PF-06672131, >=95% (HPLC); 1621002-27-4
Probe Type
ABPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 453.9
Lipid-water partition coefficient (xlogp) 3.7
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C23H21ClFN5O2
IUPAC Name
(E)-N-[4-(3-chloro-4-fluoroanilino)-7-prop-2-ynoxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Canonical SMILES
CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCC#C
InChI
InChI=1S/C23H21ClFN5O2/c1-4-10-32-21-13-19-16(12-20(21)29-22(31)6-5-9-30(2)3)23(27-14-26-19)28-15-7-8-18(25)17(24)11-15/h1,5-8,11-14H,9-10H2,2-3H3,(H,29,31)(H,26,27,28)/b6-5+
InChIKey
XZAHPCGWUZFHBI-AATRIKPKSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

275 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
(E3-independent) E2 ubiquitin-conjugating enzyme (UBE2O) LDTP11601 C182; C370  LDD0017 
26S proteasome non-ATPase regulatory subunit 1 (PSMD1) LDTP10869 C898  LDD0152 
26S proteasome non-ATPase regulatory subunit 12 (PSMD12) LDTP00224 C255  LDD0017 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 C114  LDD0017 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 C170; C193  LDD0017 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 C58  LDD0152 
26S proteasome regulatory subunit 7 (PSMC2) LDTP03797 C377  LDD0017 
26S proteasome regulatory subunit 8 (PSMC5) LDTP04963 C112  LDD0152 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 C214  LDD0017 
4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) LDTP04232 C45  LDD0152 
5'-nucleotidase domain-containing protein 1 (NT5DC1) LDTP17247 C119  LDD0017 
6-phosphogluconate dehydrogenase, decarboxylating (PGD) LDTP04499 C170  LDD0152 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 C237; C442; C447  LDD0017 
Abasic site processing protein HMCES (HMCES) LDTP10322 C266  LDD0152 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 C119  LDD0152 
Actin, cytoplasmic 1 (ACTB) LDTP04876 C17  LDD0017 
Actin, cytoplasmic 2 (ACTG1) LDTP05059 C17  LDD0152 
Adenosine 5'-monophosphoramidase HINT1 (HINT1) LDTP04306 C84  LDD0152 
Adenosylhomocysteinase (AHCY) LDTP03242 C195  LDD0017 
Adenylosuccinate synthetase isozyme 2 (ADSS2) LDTP03541 C58  LDD0152 
ADP-dependent glucokinase (ADPGK) LDTP11127 C40  LDD0017 
ADP-ribosylation factor-related protein 1 (ARFRP1) LDTP05982 C125  LDD0017 
Aldehyde dehydrogenase family 16 member A1 (ALDH16A1) LDTP15371 C350  LDD0152 
Aldo-keto reductase family 1 member A1 (AKR1A1) LDTP02729 C5  LDD0017 
Alpha-enolase (ENO1) LDTP02159 C337  LDD0152 
Aminopeptidase B (RNPEP) LDTP15993 C181; C254  LDD0017 
AMP deaminase 2 (AMPD2) LDTP05289 C107; C230  LDD0017 
Anaphase-promoting complex subunit 7 (ANAPC7) LDTP13409 C329; C509  LDD0017 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 C369; C502  LDD0017 
Asparagine--tRNA ligase, cytoplasmic (NARS1) LDTP00866 C438  LDD0017 
Aspartate--tRNA ligase, mitochondrial (DARS2) LDTP07581 C152  LDD0017 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 C475  LDD0017 
ATP-citrate synthase (ACLY) LDTP04561 C229  LDD0152 
ATP-dependent RNA helicase A (DHX9) LDTP05550 C242  LDD0017 
ATP-dependent RNA helicase DDX1 (DDX1) LDTP09766 C231  LDD0152 
ATP-dependent RNA helicase DDX19A (DDX19A) LDTP12646 C392  LDD0017 
ATP-dependent RNA helicase DDX3X (DDX3X) LDTP00314 C341  LDD0017 
ATP-dependent RNA helicase DDX3Y (DDX3Y) LDTP00664 C339  LDD0152 
Atypical kinase COQ8B, mitochondrial (COQ8B) LDTP10201 C147  LDD0017 
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPSS1) LDTP00717 C8  LDD0017 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 C856; C1480  LDD0017 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 C295  LDD0017 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 C143; C147  LDD0152 
Calcium-independent phospholipase A2-gamma (PNPLA8) LDTP12318 C559  LDD0152 
Calpain-1 catalytic subunit (CAPN1) LDTP02204 C11; C351  LDD0017 
Calpain-2 catalytic subunit (CAPN2) LDTP02911 C82  LDD0017 
Carbonyl reductase [NADPH] 1 (CBR1) LDTP02831 C122  LDD0017 
Catechol O-methyltransferase (COMT) LDTP03145 C223  LDD0017 
Cathepsin D (CTSD) LDTP02198 C329  LDD0017 
Cell division control protein 42 homolog (CDC42) LDTP04886 C157  LDD0152 
Citrate synthase, mitochondrial (CS) LDTP01205 C101  LDD0152 
Cleavage and polyadenylation specificity factor subunit 2 (CPSF2) LDTP13053 C335; C621  LDD0017 
CTP synthase 1 (CTPS1) LDTP02922 C216; C362  LDD0017 
CTP synthase 2 (CTPS2) LDTP12505 C216  LDD0017 
Cullin-4A (CUL4A) LDTP05949 C289  LDD0017 
Cullin-associated NEDD8-dissociated protein 1 (CAND1) LDTP08296 C131; C571; C1007  LDD0017 
Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) LDTP03610 C410  LDD0152 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 C192  LDD0017 
Cytochrome c1, heme protein, mitochondrial (CYC1) LDTP02283 C271  LDD0152 
Cytosol aminopeptidase (LAP3) LDTP03455 C129  LDD0152 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 C369  LDD0017 
DCN1-like protein 1 (DCUN1D1) LDTP10349 C115  LDD0017 
Delta(24)-sterol reductase (DHCR24) LDTP06375 C499  LDD0017 
Deoxycytidylate deaminase (DCTD) LDTP03643 C6  LDD0152 
Deoxyhypusine synthase (DHPS) LDTP04248 C177  LDD0017 
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT) LDTP03669 C166; C222  LDD0017 
Developmentally-regulated GTP-binding protein 1 (DRG1) LDTP13836 C195  LDD0152 
Dihydrofolate reductase 2, mitochondrial (DHFR2) LDTP08357 C183  LDD0152 
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) LDTP02362 C85  LDD0152 
DNA (cytosine-5)-methyltransferase 1 (DNMT1) LDTP03350 C62  LDD0017 
DNA helicase B (HELB) LDTP09239 C876  LDD0152 
DNA polymerase alpha subunit B (POLA2) LDTP06069 C198  LDD0017 
DNA replication licensing factor MCM2 (MCM2) LDTP04286 C522; C584  LDD0017 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 C407  LDD0017 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 C197  LDD0152 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 C91  LDD0017 
DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 C223; C232; C373; C795  LDD0017 
DNA-directed RNA polymerase I subunit RPA1 (POLR1A) LDTP01636 C937  LDD0017 
DNA-directed RNA polymerase I subunit RPA34 (POLR1G) LDTP00642 C150  LDD0017 
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase (ALG3) LDTP09841 C21  LDD0017 
Double-stranded RNA-specific adenosine deaminase (ADAR) LDTP04690 C1224  LDD0017 
E3 ubiquitin-protein ligase HUWE1 (HUWE1) LDTP08135 C1567  LDD0017 
E3 ubiquitin-protein ligase listerin (LTN1) LDTP01430 C981  LDD0017 
E3 ubiquitin-protein ligase RNF213 (RNF213) LDTP07283 C614; C4348  LDD0017 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 C31; C411  LDD0152 
Elongation factor 2 (EEF2) LDTP02672 C41; C290; C567  LDD0017 
Elongation factor G, mitochondrial (GFM1) LDTP10774 C723  LDD0152 
Elongation factor-like GTPase 1 (EFL1) LDTP08023 C831  LDD0152 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 C193  LDD0152 
Endoplasmic reticulum metallopeptidase 1 (ERMP1) LDTP08017 C43  LDD0017 
Ephrin type-A receptor 2 (EPHA2) LDTP03474 C753  LDD0017 
Epidermal growth factor receptor (EGFR) LDTP01785 C337; C470; C1049  LDD0017 
Epoxide hydrolase 4 (EPHX4) LDTP17617 C287  LDD0017 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 C131  LDD0017 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 C327  LDD0017 
Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3) LDTP03915 C434  LDD0017 
Exosome complex exonuclease RRP44 (DIS3) LDTP13887 C814  LDD0152 
F-box only protein 2 (FBXO2) LDTP13419 C71  LDD0152 
Fatty acid synthase (FASN) LDTP04243 C212; C1141; C1186; C1403  LDD0017 
Fructose-bisphosphate aldolase A (ALDOA) LDTP02008 C339  LDD0017 
Gamma-glutamylcyclotransferase (GGCT) LDTP01164 C6  LDD0017 
GDP-mannose 4,6 dehydratase (GMDS) LDTP00999 C92  LDD0152 
Glutamate dehydrogenase 2, mitochondrial (GLUD2) LDTP04256 C172  LDD0152 
Glutamate--cysteine ligase catalytic subunit (GCLC) LDTP04185 C501  LDD0017 
Glutaminase kidney isoform, mitochondrial (GLS) LDTP01465 C283  LDD0017 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) LDTP05481 C264  LDD0017 
Glutaredoxin-1 (GLRX) LDTP03786 C8  LDD0017 
Glutaredoxin-3 (GLRX3) LDTP01374 C229  LDD0017 
Glutathione S-transferase Mu 3 (GSTM3) LDTP03103 C178; C208  LDD0152 
Glutathione S-transferase P (GSTP1) LDTP02333 C48  LDD0017 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 C152; C156  LDD0017 
Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2) LDTP04032 C188  LDD0017 
Glycogen synthase kinase-3 beta (GSK3B) LDTP04319 C14  LDD0017 
GMP reductase 2 (GMPR2) LDTP13080 C348  LDD0017 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 C456; C489; C523  LDD0017 
GTP-binding nuclear protein Ran (RAN) LDTP05007 C112; C120  LDD0017 
Guanine nucleotide-binding protein-like 1 (GNL1) LDTP14676 C365; C412  LDD0017 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 C603  LDD0017 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 C572  LDD0017 
Histidine--tRNA ligase, cytoplasmic (HARS1) LDTP02602 C507; C509  LDD0017 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 C299  LDD0017 
Histone-arginine methyltransferase CARM1 (CARM1) LDTP08352 C26  LDD0017 
Histone-lysine N-trimethyltransferase SMYD5 (SMYD5) LDTP07388 C194  LDD0152 
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL) LDTP03794 C323  LDD0017 
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1) LDTP05301 C12; C406  LDD0017 
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) LDTP01782 C106  LDD0017 
Inorganic pyrophosphatase (PPA1) LDTP14854 C270  LDD0017 
Inositol polyphosphate 5-phosphatase OCRL (OCRL) LDTP05326 C611  LDD0152 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 C114  LDD0017 
Kynurenine--oxoglutarate transaminase 3 (KYAT3) LDTP07763 C416  LDD0152 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 C131  LDD0017 
L-lactate dehydrogenase B chain (LDHB) LDTP02179 C164  LDD0152 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 C305  LDD0017 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 C147  LDD0152 
Lon protease homolog, mitochondrial (LONP1) LDTP03817 C520  LDD0017 
Long-chain-fatty-acid--CoA ligase 4 (ACSL4) LDTP00982 C420  LDD0017 
Lymphoid-specific helicase (HELLS) LDTP12552 C836  LDD0017 
Lymphokine-activated killer T-cell-originated protein kinase (PBK) LDTP10500 C22; C70  LDD0017 
Lysine--tRNA ligase (KARS1) LDTP06294 C427; C434  LDD0152 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 C137  LDD0152 
Medium-chain acyl-CoA ligase ACSF2, mitochondrial (ACSF2) LDTP10177 C462  LDD0152 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 C12; C333  LDD0017 
Multifunctional protein CAD (CAD) LDTP03401 C183; C1889  LDD0017 
Myosin-9 (MYH9) LDTP03764 C91; C988; C1379  LDD0017 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 C58; C721  LDD0017 
N-alpha-acetyltransferase 16, NatA auxiliary subunit (NAA16) LDTP07455 C58  LDD0152 
N-terminal kinase-like protein (SCYL1) LDTP10503 C512  LDD0017 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 C936  LDD0017 
Nardilysin (NRDC) LDTP00886 C674  LDD0152 
NEDD8-conjugating enzyme Ubc12 (UBE2M) LDTP04898 C65  LDD0017 
Neutral alpha-glucosidase AB (GANAB) LDTP06192 C47  LDD0152 
Nuclear pore complex protein Nup98-Nup96 (NUP98) LDTP04547 C1027; C1068  LDD0017 
Ornithine aminotransferase, mitochondrial (OAT) LDTP02021 C150  LDD0017 
OTU domain-containing protein 4 (OTUD4) LDTP05313 C686  LDD0017 
Outer mitochondrial transmembrane helix translocase (ATAD1) LDTP09070 C359  LDD0017 
Parkinson disease protein 7 (PARK7) LDTP10878 C53  LDD0152 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 C161  LDD0017 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 C396  LDD0152 
Peroxiredoxin-1 (PRDX1) LDTP05503 C173  LDD0017 
Peroxiredoxin-4 (PRDX4) LDTP05773 C245  LDD0017 
Peroxiredoxin-5, mitochondrial (PRDX5) LDTP03512 C100  LDD0017 
Peroxiredoxin-6 (PRDX6) LDTP03510 C47; C91  LDD0017 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 C449  LDD0017 
Phenylalanine--tRNA ligase alpha subunit (FARSA) LDTP13831 C493  LDD0017 
Phosphatidylinositol 4-kinase alpha (PI4KA) LDTP03981 C246  LDD0017 
Phosphoglucomutase-1 (PGM1) LDTP03818 C160  LDD0152 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 C108; C316  LDD0017 
Phosphoglycerate mutase 1 (PGAM1) LDTP02963 C153  LDD0152 
Phospholipid scramblase 1 (PLSCR1) LDTP00558 C254  LDD0017 
Phosphomannomutase 2 (PMM2) LDTP00606 C9  LDD0017 
Phosphoribosylformylglycinamidine synthase (PFAS) LDTP00527 C270  LDD0017 
Platelet-activating factor acetylhydrolase IB subunit alpha1 (PAFAH1B3) LDTP06315 C205  LDD0152 
Platelet-activating factor acetylhydrolase IB subunit alpha2 (PAFAH1B2) LDTP05078 C35  LDD0152 
Poly [ADP-ribose] polymerase 1 (PARP1) LDTP02375 C311  LDD0152 
Poly(A) polymerase alpha (PAPOLA) LDTP04394 C118  LDD0152 
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (DHX16) LDTP00915 C714  LDD0152 
Probable ATP-dependent RNA helicase DDX27 (DDX27) LDTP10358 C248  LDD0017 
Probable ATP-dependent RNA helicase DDX5 (DDX5) LDTP02924 C234  LDD0017 
Probable ATP-dependent RNA helicase DDX52 (DDX52) LDTP13904 C536  LDD0017 
Probable ATP-dependent RNA helicase DDX6 (DDX6) LDTP03348 C102  LDD0017 
Probable E3 ubiquitin-protein ligase HERC1 (HERC1) LDTP06461 C56  LDD0017 
Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (USP9Y) LDTP00300 C674  LDD0017 
Proliferation-associated protein 2G4 (PA2G4) LDTP13750 C296  LDD0152 
Proprotein convertase subtilisin/kexin type 6 (PCSK6) LDTP03468 C965  LDD0152 
Prostaglandin E synthase 3 (PTGES3) LDTP06338 C40  LDD0017 
Protein arginine N-methyltransferase 1 (PRMT1) LDTP10997 C272; C360  LDD0017 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 C244  LDD0152 
Protein FRA10AC1 (FRA10AC1) LDTP07896 C180  LDD0152 
Protein NDRG3 (NDRG3) LDTP18530 C290  LDD0152 
Protein phosphatase 1G (PPM1G) LDTP00616 C351  LDD0152 
Protein phosphatase methylesterase 1 (PPME1) LDTP14092 C312; C386  LDD0017 
Protein PML (PML) LDTP03496 C389  LDD0017 
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 C524  LDD0152 
Proto-oncogene tyrosine-protein kinase Src (SRC) LDTP02638 C403  LDD0017 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 C190  LDD0152 
Putative elongation factor 1-alpha-like 3 (EEF1A1P5) LDTP15029 C234; C411  LDD0017 
Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1) LDTP03644 C262  LDD0017 
Pyruvate kinase PKM (PKM) LDTP02733 C49; C152; C326; C358  LDD0017 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 C178  LDD0017 
Ras-related C3 botulinum toxin substrate 2 (RAC2) LDTP02768 C157  LDD0152 
Ras-related protein Rab-13 (RAB13) LDTP04401 C123  LDD0152 
Ras-related protein Rab-1A (RAB1A) LDTP05006 C126  LDD0152 
Ras-related protein Rab-21 (RAB21) LDTP13512 C29  LDD0017 
Ras-related protein Rab-23 (RAB23) LDTP13531 C130  LDD0017 
Ras-related protein Rab-3B (RAB3B) LDTP03048 C184  LDD0017 
Ras-related protein Rab-3D (RAB3D) LDTP01659 C184  LDD0152 
Ras-related protein Rab-8A (RAB8A) LDTP04888 C123  LDD0152 
Replication factor C subunit 2 (RFC2) LDTP03726 C88; C255  LDD0017 
Rho-related GTP-binding protein RhoC (RHOC) LDTP02248 C16  LDD0017 
Ribonucleoside-diphosphate reductase large subunit (RRM1) LDTP03259 C492  LDD0017 
Ribose-phosphate pyrophosphokinase 2 (PRPS2) LDTP02592 C91  LDD0017 
Ribose-phosphate pyrophosphokinase 3 (PRPS1L1) LDTP03097 C91; C165  LDD0152 
Ribosomal biogenesis protein LAS1L (LAS1L) LDTP14074 C306  LDD0017 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 C184  LDD0017 
RNA N6-adenosine-methyltransferase METTL16 (METTL16) LDTP08317 C57  LDD0017 
RuvB-like 1 (RUVBL1) LDTP13816 C94  LDD0017 
RuvB-like 2 (RUVBL2) LDTP13787 C227  LDD0152 
S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) LDTP00890 C272  LDD0017 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 C136  LDD0017 
S-phase kinase-associated protein 1 (SKP1) LDTP05052 C120; C160  LDD0017 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 C447; C997  LDD0017 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 C91  LDD0152 
Serine/threonine-protein kinase 26 (STK26) LDTP13031 C392  LDD0152 
Serine/threonine-protein kinase N2 (PKN2) LDTP06536 C804  LDD0017 
Serine/threonine-protein kinase Nek9 (NEK9) LDTP09412 C260  LDD0017 
Serine/threonine-protein kinase PAK 2 (PAK2) LDTP05776 C390  LDD0017 
Serine/threonine-protein kinase PLK1 (PLK1) LDTP04555 C212  LDD0017 
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PPP2R2A) LDTP05046 C13  LDD0152 
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D) LDTP06199 C484  LDD0152 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 C154; C329; C390  LDD0017 
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PPP1CC) LDTP03819 C140  LDD0152 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 C97; C134  LDD0017 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 C249; C374; C663; C705  LDD0017 
Sorbitol dehydrogenase (SORD) LDTP05258 C106; C350  LDD0152 
SRSF protein kinase 1 (SRPK1) LDTP10809 C188  LDD0017 
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (NSDHL) LDTP06455 C86  LDD0017 
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (SUCLG1) LDTP04566 C172  LDD0152 
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (OXCT1) LDTP04715 C235  LDD0152 
Sulfide:quinone oxidoreductase, mitochondrial (SQOR) LDTP14278 C201  LDD0152 
SUMO-activating enzyme subunit 2 (UBA2) LDTP13156 C30  LDD0017 
Telomerase RNA component interacting RNase (TRIR) LDTP11055 C165  LDD0152 
Thioredoxin (TXN) LDTP02502 C73  LDD0017 
Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) LDTP03515 C229  LDD0017 
Thymidine kinase, cytosolic (TK1) LDTP02022 C3; C230  LDD0017 
Transaldolase (TALDO1) LDTP03847 C250  LDD0017 
Transcription initiation factor IIB (GTF2B) LDTP05240 C223  LDD0017 
Transforming protein RhoA (RHOA) LDTP04927 C159  LDD0152 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 C522  LDD0017 
Translin (TSN) LDTP06427 C225  LDD0017 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 C550  LDD0152 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 C41; C93; C298; C506  LDD0017 
Tripeptidyl-peptidase 2 (TPP2) LDTP03469 C787  LDD0017 
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (TRMT61A) LDTP10320 C209  LDD0017 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 C347  LDD0152 
Tubulin alpha-1B chain (TUBA1B) LDTP05074 C295; C347; C376  LDD0017 
Tubulin alpha-1C chain (TUBA1C) LDTP11074 C295; C347; C376  LDD0017 
Tyrosine--tRNA ligase, cytoplasmic (YARS1) LDTP04617 C250; C501; C519  LDD0017 
Tyrosine-protein kinase CSK (CSK) LDTP03944 C290  LDD0017 
Tyrosine-protein kinase Lyn (LYN) LDTP02232 C203  LDD0152 
Tyrosine-protein kinase Yes (YES1) LDTP02231 C410  LDD0152 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 C502  LDD0017 
Ubiquitin carboxyl-terminal hydrolase 15 (USP15) LDTP14051 C264  LDD0017 
Ubiquitin carboxyl-terminal hydrolase 7 (USP7) LDTP09962 C961  LDD0017 
Ubiquitin-conjugating enzyme E2 L5 (UBE2L5) LDTP16509 C86  LDD0017 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 C234; C632  LDD0152 
Ubiquitin-like-conjugating enzyme ATG3 (ATG3) LDTP12599 C182  LDD0017 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 C276  LDD0017 
UDP-N-acetylhexosamine pyrophosphorylase (UAP1) LDTP06517 C268  LDD0017 
Up-regulator of cell proliferation (URGCP) LDTP09404 C868  LDD0017 
Uridine 5'-monophosphate synthase (UMPS) LDTP02548 C174  LDD0017 
Uridine-cytidine kinase 2 (UCK2) LDTP11571 C197  LDD0017 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 C254  LDD0017 
Valine--tRNA ligase (VARS1) LDTP03366 C41; C663  LDD0152 
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) LDTP04289 C237  LDD0152 
X-ray repair cross-complementing protein 5 (XRCC5) LDTP02642 C296  LDD0152 
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⏷ Show the Full List of 275 Enzyme
78 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
14-3-3 protein theta (YWHAQ) LDTP03385 C134  LDD0017 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 C25  LDD0152 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 C56  LDD0152 
ADP/ATP translocase 2 (SLC25A5) LDTP02087 C160; C257  LDD0017 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 C257  LDD0152 
Aladin (AAAS) LDTP12510 C2  LDD0017 
Annexin A1 (ANXA1) LDTP02010 C343  LDD0017 
Annexin A2 (ANXA2) LDTP02199 C9; C133; C335  LDD0017 
Annexin A5 (ANXA5) LDTP02307 C316  LDD0017 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 C353  LDD0017 
AP-2 complex subunit beta (AP2B1) LDTP05038 C95  LDD0017 
ATP synthase protein 8 (MT-ATP8) LDTP01988 C59  LDD0152 
ATP synthase subunit f, mitochondrial (ATP5MF) LDTP04723 C7  LDD0152 
ATP synthase subunit O, mitochondrial (ATP5PO) LDTP04150 C141  LDD0017 
Calreticulin (CALR) LDTP03402 C105  LDD0152 
Catenin delta-1 (CTNND1) LDTP01037 C692  LDD0017 
CD2-associated protein (CD2AP) LDTP14131 C540  LDD0152 
Chloride channel CLIC-like protein 1 (CLCC1) LDTP10804 C550  LDD0017 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 C178  LDD0017 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 C100  LDD0017 
Clathrin heavy chain 1 (CLTC) LDTP05252 C436; C491; C753; C870  LDD0017 
Clathrin heavy chain 2 (CLTCL1) LDTP04578 C459; C617; C736  LDD0017 
Copine-3 (CPNE3) LDTP01133 C5  LDD0017 
Cystatin-B (CSTB) LDTP02009 C3  LDD0017 
Desmoplakin (DSP) LDTP02815 C174; C2776  LDD0017 
Dihydropyrimidinase-related protein 2 (DPYSL2) LDTP06554 C504  LDD0017 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) LDTP02057 C545  LDD0152 
Eukaryotic translation initiation factor 5A-1 (EIF5A) LDTP05056 C22  LDD0152 
Exocyst complex component 7 (EXOC7) LDTP13716 C667  LDD0152 
Exportin-1 (XPO1) LDTP00501 C119; C528  LDD0017 
Exportin-2 (CSE1L) LDTP04662 C272; C842  LDD0017 
Exportin-5 (XPO5) LDTP12142 C1052; C1131  LDD0017 
Extended synaptotagmin-1 (ESYT1) LDTP11161 C370  LDD0017 
Filamin-A (FLNA) LDTP03107 C2543  LDD0017 
Filamin-B (FLNB) LDTP01197 C2501  LDD0017 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1) LDTP05017 C204  LDD0017 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2) LDTP05020 C204  LDD0152 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 C366; C521; C564  LDD0017 
Histone deacetylase complex subunit SAP18 (SAP18) LDTP00270 C26  LDD0017 
Importin subunit alpha-5 (KPNA1) LDTP04502 C424  LDD0017 
Importin subunit alpha-7 (KPNA6) LDTP01031 C422  LDD0017 
Importin subunit beta-1 (KPNB1) LDTP06242 C543  LDD0017 
Importin-5 (IPO5) LDTP00266 C733  LDD0017 
Importin-7 (IPO7) LDTP01574 C736  LDD0017 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 C59; C131  LDD0017 
Major vault protein (MVP) LDTP06203 C572  LDD0152 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 C129  LDD0017 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 C330  LDD0017 
mRNA export factor RAE1 (RAE1) LDTP05122 C106  LDD0152 
Neuron-specific calcium-binding protein hippocalcin (HPCA) LDTP05191 C185  LDD0017 
Nuclear pore complex protein Nup155 (NUP155) LDTP01295 C974  LDD0017 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 C422  LDD0017 
Nucleoporin NDC1 (NDC1) LDTP11213 C468  LDD0017 
Nucleoporin NUP188 (NUP188) LDTP07064 C9  LDD0017 
Oligosaccharyltransferase complex subunit OSTC (OSTC) LDTP12526 C14  LDD0017 
Phosphatidylinositol transfer protein beta isoform (PITPNB) LDTP04213 C94  LDD0152 
Prohibitin 1 (PHB1) LDTP03717 C69  LDD0017 
Protein S100-A16 (S100A16) LDTP10313 C4  LDD0017 
Ran GTPase-activating protein 1 (RANGAP1) LDTP04082 C141; C303  LDD0017 
Signal recognition particle 9 kDa protein (SRP9) LDTP04259 C48  LDD0017 
Signal recognition particle subunit SRP68 (SRP68) LDTP13262 C562  LDD0017 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 C138; C168; C182  LDD0017 
Solute carrier family 12 member 2 (SLC12A2) LDTP04653 C630  LDD0152 
Solute carrier family 12 member 9 (SLC12A9) LDTP11397 C911  LDD0017 
Sorting nexin-6 (SNX6) LDTP13661 C149; C264  LDD0017 
Sorting nexin-8 (SNX8) LDTP14173 C200  LDD0017 
Spectrin beta chain, non-erythrocytic 1 (SPTBN1) LDTP05273 C112; C1389  LDD0152 
Store-operated calcium entry-associated regulatory factor (SARAF) LDTP10148 C83  LDD0152 
T-complex protein 1 subunit delta (CCT4) LDTP04391 C221; C252; C295; C379  LDD0017 
Talin-1 (TLN1) LDTP14031 C1939  LDD0017 
Tissue factor (F3) LDTP02686 C241  LDD0152 
Translocation protein SEC62 (SEC62) LDTP15838 C55  LDD0152 
Tumor necrosis factor alpha-induced protein 2 (TNFAIP2) LDTP14808 C45  LDD0017 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 C232  LDD0017 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 C47; C76  LDD0017 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 C2; C8; C65  LDD0017 
Volume-regulated anion channel subunit LRRC8C (LRRC8C) LDTP09459 C54  LDD0152 
Zinc transporter 7 (SLC30A7) LDTP09180 C308  LDD0152 
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⏷ Show the Full List of 78 Transporter and channel
9 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
eIF5-mimic protein 1 (BZW2) LDTP14241 C270  LDD0017 
Gamma-interferon-inducible protein 16 (IFI16) LDTP06602 C679  LDD0152 
General transcription factor II-I (GTF2I) LDTP05101 C215; C475  LDD0017 
Glucocorticoid receptor (NR3C1) LDTP02016 C287  LDD0017 
Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1) LDTP06748 C14  LDD0017 
NF-kappa-B inhibitor epsilon (NFKBIE) LDTP00221 C498  LDD0017 
Nuclear factor NF-kappa-B p105 subunit (NFKB1) LDTP03017 C87  LDD0152 
Signal transducer and activator of transcription 1-alpha/beta (STAT1) LDTP03969 C492  LDD0017 
Transcription factor A, mitochondrial (TFAM) LDTP05235 C246  LDD0017 
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⏷ Show the Full List of 9 Transcription factor
2 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Cadherin EGF LAG seven-pass G-type receptor 1 (CELSR1) LDTP12844 C2638  LDD0152 
Taste receptor type 2 member 30 (TAS2R30) LDTP14744 C317  LDD0017 
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1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Cell surface glycoprotein MUC18 (MCAM) LDTP04020 C116  LDD0152 
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1 Cytokine and receptor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Interleukin-18 (IL18) LDTP06037 C10  LDD0152 
------------------------------------------------------------------------------------
286 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
14-3-3 protein sigma (SFN) LDTP03618 C38  LDD0017 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 C202  LDD0017 
26S proteasome non-ATPase regulatory subunit 6 (PSMD6) LDTP06273 C58  LDD0152 
60S ribosomal export protein NMD3 (NMD3) LDTP10200 C256  LDD0152 
A-kinase anchor protein 1, mitochondrial (AKAP1) LDTP09837 C438  LDD0017 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 C27  LDD0152 
Actin-like protein 6A (ACTL6A) LDTP01756 C32  LDD0017 
Actin-like protein 6B (ACTL6B) LDTP01421 C32  LDD0152 
Actin-related protein 10 (ACTR10) LDTP16150 C37  LDD0017 
Actin-related protein 3 (ACTR3) LDTP04902 C34  LDD0017 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 C93; C356  LDD0152 
ADP-ribosylation factor GTPase-activating protein 3 (ARFGAP3) LDTP12306 C241  LDD0017 
Afadin (AFDN) LDTP04679 C1684  LDD0017 
AH receptor-interacting protein (AIP) LDTP00202 C208  LDD0152 
Alpha-actinin-1 (ACTN1) LDTP02631 C370; C480  LDD0017 
Alpha-catulin (CTNNAL1) LDTP13159 C438  LDD0017 
Alpha-taxilin (TXLNA) LDTP03886 C523  LDD0017 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 C205  LDD0017 
Ankyrin repeat domain-containing protein 17 (ANKRD17) LDTP01155 C58  LDD0017 
Annexin A3 (ANXA3) LDTP02620 C202  LDD0017 
Apoptosis inhibitor 5 (API5) LDTP11575 C297  LDD0152 
Armadillo repeat-containing protein 8 (ARMC8) LDTP08466 C3  LDD0017 
Armadillo repeat-containing X-linked protein 5 (ARMCX5) LDTP19497 C300  LDD0152 
Ataxin-10 (ATXN10) LDTP13091 C354; C382  LDD0017 
BAG family molecular chaperone regulator 5 (BAG5) LDTP13507 C191  LDD0017 
Bifunctional purine biosynthesis protein ATIC (ATIC) LDTP03612 C101  LDD0017 
BLOC-2 complex member HPS3 (HPS3) LDTP09994 C944  LDD0152 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 C230  LDD0017 
BRISC and BRCA1-A complex member 2 (BABAM2) LDTP12788 C34  LDD0017 
Calcium homeostasis endoplasmic reticulum protein (CHERP) LDTP08570 C69  LDD0017 
Calpain small subunit 1 (CAPNS1) LDTP02047 C144  LDD0017 
Calponin-2 (CNN2) LDTP10864 C61; C215  LDD0017 
Calponin-3 (CNN3) LDTP06383 C59  LDD0017 
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) LDTP02511 C362  LDD0152 
Caprin-1 (CAPRIN1) LDTP06121 C226  LDD0152 
Catenin alpha-1 (CTNNA1) LDTP03711 C116; C337  LDD0152 
Catenin beta-1 (CTNNB1) LDTP03712 C466  LDD0152 
CCR4-NOT transcription complex subunit 2 (CNOT2) LDTP12925 C175  LDD0017 
CDGSH iron-sulfur domain-containing protein 2 (CISD2) LDTP08902 C92  LDD0017 
Cell cycle and apoptosis regulator protein 2 (CCAR2) LDTP08760 C754  LDD0152 
Cell death regulator Aven (AVEN) LDTP16066 C169; C193  LDD0017 
Charged multivesicular body protein 5 (CHMP5) LDTP12948 C20  LDD0017 
Chromobox protein homolog 3 (CBX3) LDTP05778 C177  LDD0017 
Cleavage stimulation factor subunit 2 (CSTF2) LDTP03665 C150  LDD0017 
Coatomer subunit alpha (COPA) LDTP04571 C1148  LDD0017 
Coatomer subunit beta' (COPB2) LDTP03767 C56  LDD0017 
Coatomer subunit delta (ARCN1) LDTP04181 C441  LDD0152 
Cofilin-1 (CFL1) LDTP03244 C39; C139  LDD0017 
Coiled-coil domain-containing protein 25 (CCDC25) LDTP08339 C83  LDD0152 
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (CHCHD2) LDTP14251 C134  LDD0017 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 C645; C739  LDD0152 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 C78  LDD0152 
Complex III assembly factor LYRM7 (LYRM7) LDTP07200 C97  LDD0017 
Condensin complex subunit 1 (NCAPD2) LDTP06281 C1229  LDD0017 
Condensin-2 complex subunit D3 (NCAPD3) LDTP03994 C631  LDD0017 
Coronin-1C (CORO1C) LDTP13580 C420  LDD0017 
Coronin-7 (CORO7) LDTP04798 C505  LDD0152 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 C2594  LDD0017 
Cytoplasmic FMR1-interacting protein 1 (CYFIP1) LDTP07958 C1241  LDD0152 
Cytosolic Fe-S cluster assembly factor NUBP2 (NUBP2) LDTP14179 C54; C269  LDD0017 
Density-regulated protein (DENR) LDTP00808 C13  LDD0017 
Destrin (DSTN) LDTP04887 C12; C23; C163  LDD0017 
DNA mismatch repair protein Msh6 (MSH6) LDTP04518 C88  LDD0017 
DnaJ homolog subfamily A member 1 (DNAJA1) LDTP03606 C302  LDD0152 
DnaJ homolog subfamily A member 2 (DNAJA2) LDTP01073 C308  LDD0152 
DnaJ homolog subfamily B member 1 (DNAJB1) LDTP03325 C179  LDD0017 
DnaJ homolog subfamily C member 7 (DNAJC7) LDTP10920 C58  LDD0152 
Double-strand-break repair protein rad21 homolog (RAD21) LDTP00911 C392  LDD0152 
Dynactin subunit 4 (DCTN4) LDTP13402 C258  LDD0017 
EF-hand domain-containing protein D2 (EFHD2) LDTP15701 C172  LDD0017 
Elongation factor 1-delta (EEF1D) LDTP03499 C247  LDD0152 
Elongation factor 1-gamma (EEF1G) LDTP03367 C266  LDD0017 
Elongin-C (ELOC) LDTP06368 C11  LDD0152 
Embryonic polyadenylate-binding protein 2 (PABPN1L) LDTP16605 C180  LDD0152 
Eukaryotic peptide chain release factor subunit 1 (ETF1) LDTP04993 C302  LDD0152 
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) LDTP03027 C226  LDD0017 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 C78  LDD0017 
Eukaryotic translation initiation factor 3 subunit B (EIF3B) LDTP04718 C515  LDD0017 
Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 C79  LDD0017 
Eukaryotic translation initiation factor 3 subunit D (EIF3D) LDTP00619 C19  LDD0017 
Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 C25  LDD0017 
Eukaryotic translation initiation factor 3 subunit H (EIF3H) LDTP00620 C177  LDD0017 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 C81  LDD0152 
Eukaryotic translation initiation factor 3 subunit J (EIF3J) LDTP01320 C207  LDD0152 
Eukaryotic translation initiation factor 3 subunit K (EIF3K) LDTP13143 C85  LDD0017 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 C417  LDD0017 
Eukaryotic translation initiation factor 3 subunit M (EIF3M) LDTP07947 C175  LDD0017 
Eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) LDTP05421 C662; C919; C1516  LDD0017 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 C59  LDD0017 
F-actin-capping protein subunit beta (CAPZB) LDTP04127 C8; C206  LDD0017 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 C176  LDD0017 
Fascin (FSCN1) LDTP06598 C89  LDD0152 
Galectin-1 (LGALS1) LDTP02341 C3  LDD0017 
Glutamate-rich protein 6 (ERICH6) LDTP17515 C197  LDD0017 
Glycogen debranching enzyme (AGL) LDTP03762 C767  LDD0152 
GrpE protein homolog 1, mitochondrial (GRPEL1) LDTP12144 C108  LDD0017 
Guanine nucleotide-binding protein G(i) subunit alpha-2 (GNAI2) LDTP02059 C255; C287  LDD0017 
Guanine nucleotide-binding protein G(i) subunit alpha-3 (GNAI3) LDTP02306 C66; C139  LDD0152 
Guanine nucleotide-binding protein subunit beta-like protein 1 (GNB1L) LDTP18337 C5  LDD0017 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 C266  LDD0017 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 C376; C380  LDD0017 
Heat shock 70 kDa protein 4L (HSPA4L) LDTP14545 C380  LDD0152 
Heat shock protein 105 kDa (HSPH1) LDTP09811 C167; C290  LDD0017 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 C501  LDD0017 
Hepatoma-derived growth factor (HDGF) LDTP04483 C12  LDD0017 
Heterogeneous nuclear ribonucleoprotein A0 (HNRNPA0) LDTP05768 C7  LDD0152 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 C226  LDD0017 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 C267  LDD0017 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 C22; C34; C267  LDD0017 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 C205  LDD0152 
Heterogeneous nuclear ribonucleoprotein L (HNRNPL) LDTP02750 C452; C472  LDD0017 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 C99  LDD0017 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 C562; C607  LDD0017 
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) LDTP11238 C532  LDD0152 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 C50  LDD0152 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 C97  LDD0017 
Host cell factor 1 (HCFC1) LDTP04434 C1886  LDD0017 
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) LDTP00272 C336  LDD0152 
Interferon-induced protein with tetratricopeptide repeats 5 (IFIT5) LDTP05828 C476  LDD0017 
Iron-sulfur cluster assembly enzyme ISCU (ISCU) LDTP11771 C130  LDD0152 
IST1 homolog (IST1) LDTP04593 C125  LDD0017 
Junction plakoglobin (JUP) LDTP02756 C511; C609  LDD0017 
Kelch-like protein 22 (KLHL22) LDTP06904 C11  LDD0017 
KIF-binding protein (KIFBP) LDTP10263 C10  LDD0017 
Kinesin light chain 1 (KLC1) LDTP05533 C236  LDD0017 
Kinetochore protein NDC80 homolog (NDC80) LDTP00431 C449  LDD0017 
La-related protein 1 (LARP1) LDTP07605 C864  LDD0017 
Ladinin-1 (LAD1) LDTP14421 C428  LDD0017 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 C280; C330; C341; C684  LDD0017 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 C363  LDD0017 
Laminin subunit beta-1 (LAMB1) LDTP02230 C1785  LDD0017 
LanC-like protein 2 (LANCL2) LDTP12571 C121; C187  LDD0017 
Large ribosomal subunit protein bL21m (MRPL21) LDTP15237 C203  LDD0017 
Large ribosomal subunit protein eL14 (RPL14) LDTP04389 C42; C54  LDD0017 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 C16; C109  LDD0152 
Large ribosomal subunit protein eL30 (RPL30) LDTP05021 C52  LDD0017 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 C96  LDD0017 
Large ribosomal subunit protein eL36 (RPL36) LDTP14012 C48  LDD0152 
Large ribosomal subunit protein P1 (RPLP1) LDTP02107 C61  LDD0017 
Large ribosomal subunit protein uL10 (RPLP0) LDTP02109 C27; C119  LDD0017 
Large ribosomal subunit protein uL11 (RPL12) LDTP03517 C17  LDD0017 
Large ribosomal subunit protein uL11m (MRPL11) LDTP13971 C50  LDD0017 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 C28  LDD0017 
Large ribosomal subunit protein uL24m (MRPL24) LDTP15687 C190  LDD0152 
Large ribosomal subunit protein uL3 (RPL3) LDTP03865 C253  LDD0017 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 C3  LDD0017 
Large ribosomal subunit protein uL6 (RPL9; RPL9P7; RPL9P8; RPL9P9) LDTP03658 C134  LDD0152 
Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) LDTP03997 C130; C863  LDD0017 
Leucine-rich repeat-containing protein 1 (LRRC1) LDTP15885 C425  LDD0017 
Leucine-rich repeat-containing protein 57 (LRRC57) LDTP17764 C82  LDD0152 
Lipoma-preferred partner (LPP) LDTP09969 C364  LDD0017 
Malignant T-cell-amplified sequence 1 (MCTS1) LDTP13532 C14  LDD0152 
Mediator of RNA polymerase II transcription subunit 8 (MED8) LDTP10330 C31  LDD0017 
Melanoma-associated antigen 4 (MAGEA4) LDTP04041 C147  LDD0017 
MIF4G domain-containing protein (MIF4GD) LDTP00155 C49  LDD0017 
Mini-chromosome maintenance complex-binding protein (MCMBP) LDTP11197 C325  LDD0017 
Mitochondrial import receptor subunit TOM34 (TOMM34) LDTP06473 C250  LDD0152 
Mitochondrial import receptor subunit TOM70 (TOMM70) LDTP01432 C176  LDD0152 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 C129  LDD0017 
MKI67 FHA domain-interacting nucleolar phosphoprotein (NIFK) LDTP11457 C237  LDD0017 
MOB-like protein phocein (MOB4) LDTP13964 C134  LDD0017 
mRNA turnover protein 4 homolog (MRTO4) LDTP16220 C33  LDD0152 
Multifunctional methyltransferase subunit TRM112-like protein (TRMT112) LDTP13323 C33  LDD0152 
Muskelin (MKLN1) LDTP13525 C13; C582  LDD0152 
Myomegalin (PDE4DIP) LDTP07221 C603  LDD0017 
Myosin light polypeptide 6 (MYL6) LDTP04875 C2  LDD0017 
NACHT, LRR and PYD domains-containing protein 2 (NLRP2) LDTP12748 C143; C422  LDD0017 
NEDD4 family-interacting protein 1 (NDFIP1) LDTP11186 C15  LDD0017 
Neurogenic locus notch homolog protein 2 (NOTCH2) LDTP05425 C2085  LDD0017 
NHP2-like protein 1 (SNU13) LDTP04708 C30  LDD0017 
Nucleolar protein 56 (NOP56) LDTP00313 C211  LDD0152 
Nucleolin (NCL) LDTP02990 C543  LDD0152 
NudC domain-containing protein 1 (NUDCD1) LDTP10781 C7  LDD0152 
OCIA domain-containing protein 2 (OCIAD2) LDTP17157 C27  LDD0017 
Origin recognition complex subunit 3 (ORC3) LDTP13104 C711  LDD0017 
PCI domain-containing protein 2 (PCID2) LDTP07019 C399  LDD0017 
Perilipin-3 (PLIN3) LDTP01021 C60  LDD0017 
Plakophilin-3 (PKP3) LDTP14017 C129; C529  LDD0017 
Plastin-1 (PLS1) LDTP06167 C166  LDD0017 
Plastin-2 (LCP1) LDTP02691 C42; C101  LDD0017 
Plastin-3 (PLS3) LDTP02692 C167  LDD0152 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 C54; C109; C158; C194  LDD0017 
Poly(rC)-binding protein 2 (PCBP2) LDTP06367 C109; C158  LDD0017 
Polyadenylate-binding protein 1 (PABPC1) LDTP02595 C339  LDD0152 
Polyadenylate-binding protein 2 (PABPN1) LDTP08213 C205  LDD0017 
Polyamine-modulated factor 1 (PMF1) LDTP07508 C13  LDD0017 
Polypyrimidine tract-binding protein 1 (PTBP1) LDTP03364 C250  LDD0017 
Prefoldin subunit 3 (VBP1) LDTP04935 C113  LDD0017 
Prefoldin subunit 5 (PFDN5) LDTP10873 C49  LDD0152 
Prelamin-A/C (LMNA) LDTP01932 C522; C588  LDD0152 
Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 C40; C76  LDD0017 
Proliferating cell nuclear antigen (PCNA) LDTP02596 C62; C81  LDD0152 
Proteasome activator complex subunit 1 (PSME1) LDTP05484 C22; C101  LDD0017 
Proteasome activator complex subunit 2 (PSME2) LDTP13519 C91  LDD0017 
Proteasome adapter and scaffold protein ECM29 (ECPAS) LDTP07255 C1257  LDD0017 
Proteasome assembly chaperone 2 (PSMG2) LDTP10035 C195  LDD0152 
Protein CIP2A (CIP2A) LDTP09383 C337; C472  LDD0017 
Protein CMSS1 (CMSS1) LDTP18287 C55  LDD0017 
Protein diaphanous homolog 1 (DIAPH1) LDTP01011 C796; C1227  LDD0017 
Protein flightless-1 homolog (FLII) LDTP05734 C46; C289  LDD0017 
Protein HGH1 homolog (HGH1) LDTP18309 C199  LDD0017 
Protein kinase C and casein kinase substrate in neurons protein 3 (PACSIN3) LDTP13479 C421  LDD0017 
Protein KRI1 homolog (KRI1) LDTP17765 C667  LDD0017 
Protein Mis18-alpha (MIS18A) LDTP12842 C231  LDD0017 
Protein NipSnap homolog 3B (NIPSNAP3B) LDTP19920 C106  LDD0152 
Protein PRRC2C (PRRC2C) LDTP14085 C2340  LDD0017 
Protein RCC2 (RCC2) LDTP13020 C428  LDD0017 
Protein S100-A14 (S100A14) LDTP12277 C62; C74  LDD0017 
Protein S100-A2 (S100A2) LDTP03463 C22  LDD0152 
Protein transport protein Sec23A (SEC23A) LDTP06390 C74  LDD0152 
Protein transport protein Sec23B (SEC23B) LDTP06391 C767  LDD0017 
Protein unc-45 homolog A (UNC45A) LDTP11890 C503  LDD0017 
Putative heat shock protein HSP 90-beta-3 (HSP90AB3P) LDTP14955 C437  LDD0152 
Pyridoxal phosphate homeostasis protein (PLPBP) LDTP14521 C86  LDD0017 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 C202; C282  LDD0152 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 C1270  LDD0152 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 C18  LDD0017 
Reticulon-3 (RTN3) LDTP01522 C34  LDD0017 
Reticulon-4 (RTN4) LDTP12412 C1101  LDD0017 
Ribonuclease inhibitor (RNH1) LDTP02656 C220; C362  LDD0152 
Ribosomal RNA processing protein 1 homolog A (RRP1) LDTP04729 C198  LDD0017 
Ribosome maturation protein SBDS (SBDS) LDTP13966 C119  LDD0152 
RNA binding motif protein, X-linked-like-1 (RBMXL1) LDTP18146 C338  LDD0017 
RNA transcription, translation and transport factor protein (RTRAF) LDTP13782 C19  LDD0152 
RNA-binding motif, single-stranded-interacting protein 1 (RBMS1) LDTP03495 C221  LDD0152 
RNA-binding protein 14 (RBM14) LDTP10684 C90; C108  LDD0017 
RNA-binding protein 5 (RBM5) LDTP04527 C766  LDD0017 
RRP12-like protein (RRP12) LDTP14980 C317  LDD0017 
Scaffold attachment factor B1 (SAFB) LDTP06385 C225  LDD0017 
Serine/arginine-rich splicing factor 1 (SRSF1) LDTP05539 C16  LDD0152 
Serine/arginine-rich splicing factor 4 (SRSF4) LDTP05546 C115  LDD0152 
Serine/arginine-rich splicing factor 9 (SRSF9) LDTP05800 C138  LDD0017 
Serrate RNA effector molecule homolog (SRRT) LDTP11398 C412  LDD0017 
Signal recognition particle receptor subunit alpha (SRPRA) LDTP02263 C621  LDD0017 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 C246  LDD0152 
Sister chromatid cohesion protein PDS5 homolog A (PDS5A) LDTP06684 C14  LDD0152 
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) LDTP00862 C153  LDD0017 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 C69; C92  LDD0017 
Small ribosomal subunit protein eS17 (RPS17) LDTP02302 C35  LDD0152 
Small ribosomal subunit protein eS21 (RPS21) LDTP05055 C56  LDD0017 
Small ribosomal subunit protein eS28 (RPS28) LDTP05015 C27  LDD0152 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 C181  LDD0017 
Small ribosomal subunit protein eS6 (RPS6) LDTP05002 C12  LDD0017 
Small ribosomal subunit protein uS10 (RPS20) LDTP04880 C70  LDD0017 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 C131  LDD0017 
Small ribosomal subunit protein uS2 (RPSA) LDTP02312 C163  LDD0017 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 C182; C229  LDD0017 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 C172  LDD0017 
Small ribosomal subunit protein uS9 (RPS16) LDTP04966 C25  LDD0017 
SNW domain-containing protein 1 (SNW1) LDTP05930 C250  LDD0017 
Sperm-associated antigen 5 (SPAG5) LDTP10753 C1035  LDD0017 
Sperm-associated antigen 7 (SPAG7) LDTP19024 C191  LDD0017 
Splicing factor 3A subunit 3 (SF3A3) LDTP05677 C145  LDD0152 
Splicing factor 3B subunit 1 (SF3B1) LDTP01251 C1035  LDD0152 
Splicing factor 3B subunit 5 (SF3B5) LDTP11328 C76  LDD0152 
SRA stem-loop-interacting RNA-binding protein, mitochondrial (SLIRP) LDTP11645 C48  LDD0017 
Src substrate cortactin (CTTN) LDTP06094 C246  LDD0017 
Stalled ribosome sensor GCN1 (GCN1) LDTP09821 C246; C648; C1235  LDD0017 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 C608  LDD0152 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 C26; C62; C461  LDD0017 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 C523  LDD0152 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 C585  LDD0152 
T-complex protein 1 subunit alpha (TCP1) LDTP02934 C76; C147; C236; C357  LDD0017 
T-complex protein 1 subunit beta (CCT2) LDTP05113 C395; C535  LDD0017 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 C253; C493  LDD0017 
T-complex protein 1 subunit eta (CCT7) LDTP10990 C364; C450  LDD0017 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 C173; C213; C366; C398  LDD0017 
T-complex protein 1 subunit theta (CCT8) LDTP04390 C36; C244; C430  LDD0017 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 C406  LDD0017 
Target of EGR1 protein 1 (TOE1) LDTP10354 C80  LDD0017 
TBC1 domain family member 15 (TBC1D15) LDTP09363 C605  LDD0017 
Testis-expressed protein 264 (TEX264) LDTP14259 C68  LDD0017 
TIP41-like protein (TIPRL) LDTP01285 C87  LDD0017 
Transcription initiation factor TFIID subunit 7 (TAF7) LDTP06410 C72  LDD0017 
Transgelin-2 (TAGLN2) LDTP03846 C124  LDD0152 
Trichoplein keratin filament-binding protein (TCHP) LDTP11190 C11  LDD0017 
Tubulin beta chain (TUBB) LDTP02205 C303; C354  LDD0017 
U3 small nucleolar RNA-associated protein 6 homolog (UTP6) LDTP12830 C370  LDD0017 
U4/U6.U5 tri-snRNP-associated protein 1 (SART1) LDTP00727 C674  LDD0017 
Ubiquitin-like protein 5 (UBL5) LDTP11545 C18  LDD0152 
Uncharacterized protein C7orf50 (C7orf50) LDTP19918 C107  LDD0017 
UPF0488 protein C8orf33 (C8orf33) LDTP12025 C21  LDD0017 
Vigilin (HDLBP) LDTP05239 C855  LDD0152 
WD repeat-containing protein 1 (WDR1) LDTP01118 C170  LDD0152 
WD repeat-containing protein 5 (WDR5) LDTP04948 C205  LDD0152 
Zinc finger C3HC-type protein 1 (ZC3HC1) LDTP08325 C5  LDD0017 
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Full Information of The Labelling Profiles of This Probe

Qualitation: Labeling site identification
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
100 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Skin
Disease Model
Skin squamous cell carcinoma [ICD-11:2C31]
Model Name
Human skin squamous cell carcinoma cells (A431)
Interaction Atlas ID
 LDD0017 
Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
100 uM
In Vitro Experiment Model
Model Type
Cell lysate
Derived Tissue
Skin
Disease Model
Skin squamous cell carcinoma [ICD-11:2C31]
Model Name
Human skin squamous cell carcinoma cell lysate (A431)
Interaction Atlas ID
 LDD0152 
Download The Altas

References

1 Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. Mol Cell Proteomics. 2023 Jan;22(1):100455. doi: 10.1016/j.mcpro.2022.100455. Epub 2022 Nov 24.
Mass spectrometry data entry: PXD036569