Details of the Target

General Information of Target

Target ID LDTP17157
Target Name OCIA domain-containing protein 2 (OCIAD2)
Gene Name OCIAD2
Gene ID 132299
Synonyms
OCIA domain-containing protein 2; Ovarian carcinoma immunoreactive antigen-like protein
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MSPPTVPPMGVDGVSAYLMKKRHTHRKQRRKPTFLTRRNIVGCRIQHGWKEGNEPVEQWK
GTVLEQVSVKPTLYIIKYDGKDSVYGLELHRDKRVLALEILPERVPTPRIDSRLADSLIG
KAVEHVFEGEHGTKDEWKGMVLARAPVMDTWFYITYEKDPVLYMYTLLDDYKDGDLRIIP
DSNYYFPTAEQEPGEVVDSLVGKQVEHAKDDGSKRTGIFIHQVVAKPSVYFIKFDDDIHI
YVYGLVKTP
Target Bioclass
Other
Subcellular location
Endosome
Uniprot ID
Q56VL3
Ensemble ID
ENST00000273860.8
HGNC ID
HGNC:28685

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HCT15 SNV: p.R36I; p.A153T DBIA    Probe Info 
OCILY3 Insertion: p.M1? .
SUPT1 SNV: p.I139R DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 21 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
N1
 Probe Info  		100.00  LDD0242  [1]
STPyne
 Probe Info  		K12(2.27); K140(8.45); K29(2.61); K31(8.64)  LDD0277  [2]
ONAyne
 Probe Info  		K140(7.29); K146(10.00); K41(10.00)  LDD0275  [2]
JZ128-DTB
 Probe Info  		C134(0.00); C27(0.00)  LDD0462  [3]
BTD
 Probe Info  		C27(0.75)  LDD1700  [4]
Curcusone 37
 Probe Info  		2.05  LDD0188  [5]
DBIA
 Probe Info  		C27(1.31); C106(0.95); C130(0.88); C134(0.88)  LDD0078  [6]
4-Iodoacetamidophenylacetylene
 Probe Info  		C46(0.00); C27(0.00)  LDD0038  [7]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [8]
Lodoacetamide azide
 Probe Info  		C46(0.00); C27(0.00); C106(0.00); C130(0.00)  LDD0037  [7]
IPM
 Probe Info  		N.A.  LDD0025  [9]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [9]
NAIA_4
 Probe Info  		C27(0.00); C46(0.00)  LDD2226  [10]
TFBX
 Probe Info  		C106(0.00); C27(0.00)  LDD0027  [9]
WYneN
 Probe Info  		C46(0.00); C130(0.00)  LDD0021  [11]
Compound 10
 Probe Info  		N.A.  LDD2216  [12]
Compound 11
 Probe Info  		N.A.  LDD2213  [12]
PF-06672131
 Probe Info  		N.A.  LDD0017  [13]
Acrolein
 Probe Info  		N.A.  LDD0217  [14]
Methacrolein
 Probe Info  		C134(0.00); C137(0.00)  LDD0218  [14]
NAIA_5
 Probe Info  		C46(0.00); C106(0.00)  LDD2223  [10]
PAL-AfBPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C040
 Probe Info  		6.96  LDD1740  [15]
C251
 Probe Info  		35.26  LDD1924  [15]
C285
 Probe Info  		23.10  LDD1955  [15]
C289
 Probe Info  		34.30  LDD1959  [15]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C134(0.93); C130(0.71)  LDD2142  [4]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C134(1.01); C130(1.01)  LDD2112  [4]
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C27(0.86)  LDD2095  [4]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C106(0.87); C46(1.82)  LDD2117  [4]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C27(1.12); C106(0.84)  LDD2152  [4]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C27(1.32); C106(0.83)  LDD2103  [4]
 LDCM0214  AC1 HCT 116 C106(0.90); C130(0.85); C134(0.83); C137(0.84)  LDD0531  [6]
 LDCM0215  AC10 HCT 116 C106(1.01); C130(0.96); C134(0.99); C137(0.97)  LDD0532  [6]
 LDCM0216  AC100 HCT 116 C106(0.92); C130(0.74); C134(0.77); C137(0.74)  LDD0533  [6]
 LDCM0217  AC101 HCT 116 C106(0.81); C130(0.71); C134(0.74); C137(0.72)  LDD0534  [6]
 LDCM0218  AC102 HCT 116 C106(0.81); C130(0.69); C134(0.72); C137(0.72)  LDD0535  [6]
 LDCM0219  AC103 HCT 116 C106(0.76); C130(0.62); C134(0.65); C137(0.62)  LDD0536  [6]
 LDCM0220  AC104 HCT 116 C106(0.78); C130(0.61); C134(0.63); C137(0.62)  LDD0537  [6]
 LDCM0221  AC105 HCT 116 C106(0.82); C130(0.68); C134(0.70); C137(0.72)  LDD0538  [6]
 LDCM0222  AC106 HCT 116 C106(0.87); C130(0.71); C134(0.75); C137(0.72)  LDD0539  [6]
 LDCM0223  AC107 HCT 116 C106(0.91); C130(0.67); C134(0.70); C137(0.65)  LDD0540  [6]
 LDCM0224  AC108 HCT 116 C106(0.87); C130(0.76); C134(0.75); C137(0.74)  LDD0541  [6]
 LDCM0225  AC109 HCT 116 C106(0.85); C130(0.77); C134(0.77); C137(0.75)  LDD0542  [6]
 LDCM0226  AC11 HCT 116 C106(1.02); C130(0.82); C134(0.85); C137(0.90)  LDD0543  [6]
 LDCM0227  AC110 HCT 116 C106(0.86); C130(0.68); C134(0.71); C137(0.75)  LDD0544  [6]
 LDCM0228  AC111 HCT 116 C106(0.80); C130(0.69); C134(0.72); C137(0.70)  LDD0545  [6]
 LDCM0229  AC112 HCT 116 C106(0.87); C130(0.64); C134(0.70); C137(0.70)  LDD0546  [6]
 LDCM0230  AC113 HCT 116 C106(0.97); C130(0.98); C134(0.95); C137(0.89)  LDD0547  [6]
 LDCM0231  AC114 HCT 116 C106(0.96); C130(0.98); C134(0.85); C137(1.03)  LDD0548  [6]
 LDCM0232  AC115 HCT 116 C106(0.94); C130(0.92); C134(0.87); C137(0.95)  LDD0549  [6]
 LDCM0233  AC116 HCT 116 C106(0.91); C130(0.91); C134(0.91); C137(0.81)  LDD0550  [6]
 LDCM0234  AC117 HCT 116 C106(0.88); C130(1.04); C134(1.04); C137(0.88)  LDD0551  [6]
 LDCM0235  AC118 HCT 116 C106(0.92); C130(1.01); C134(0.92); C137(0.98)  LDD0552  [6]
 LDCM0236  AC119 HCT 116 C106(0.86); C130(0.95); C134(0.80); C137(0.92)  LDD0553  [6]
 LDCM0237  AC12 HCT 116 C106(0.92); C130(0.98); C134(1.01); C137(0.98)  LDD0554  [6]
 LDCM0238  AC120 HCT 116 C106(0.91); C130(0.91); C134(0.84); C137(0.83)  LDD0555  [6]
 LDCM0239  AC121 HCT 116 C106(0.91); C130(1.16); C134(1.02); C137(1.02)  LDD0556  [6]
 LDCM0240  AC122 HCT 116 C106(0.88); C130(0.99); C134(0.94); C137(0.97)  LDD0557  [6]
 LDCM0241  AC123 HCT 116 C106(0.80); C130(1.02); C134(1.04); C137(0.91)  LDD0558  [6]
 LDCM0242  AC124 HCT 116 C106(0.91); C130(1.11); C134(1.08); C137(0.96)  LDD0559  [6]
 LDCM0243  AC125 HCT 116 C106(0.92); C130(1.11); C134(1.08); C137(1.01)  LDD0560  [6]
 LDCM0244  AC126 HCT 116 C106(0.92); C130(0.96); C134(0.89); C137(0.94)  LDD0561  [6]
 LDCM0245  AC127 HCT 116 C106(0.88); C130(1.00); C134(0.85); C137(0.95)  LDD0562  [6]
 LDCM0246  AC128 HCT 116 C106(1.02); C130(0.98); C134(1.01); C137(1.00)  LDD0563  [6]
 LDCM0247  AC129 HCT 116 C106(1.01); C130(1.08); C134(1.14); C137(1.08)  LDD0564  [6]
 LDCM0249  AC130 HCT 116 C106(1.00); C130(1.08); C134(1.08); C137(1.09)  LDD0566  [6]
 LDCM0250  AC131 HCT 116 C106(0.99); C130(1.02); C134(0.98); C137(1.03)  LDD0567  [6]
 LDCM0251  AC132 HCT 116 C106(1.30); C130(1.39); C134(1.41); C137(1.42)  LDD0568  [6]
 LDCM0252  AC133 HCT 116 C106(1.11); C130(1.13); C134(1.11); C137(1.15)  LDD0569  [6]
 LDCM0253  AC134 HCT 116 C106(1.16); C130(0.98); C134(0.99); C137(1.01)  LDD0570  [6]
 LDCM0254  AC135 HCT 116 C106(1.16); C130(1.17); C134(1.16); C137(1.21)  LDD0571  [6]
 LDCM0255  AC136 HCT 116 C106(1.23); C130(1.05); C134(1.05); C137(1.08)  LDD0572  [6]
 LDCM0256  AC137 HCT 116 C106(1.21); C130(1.15); C134(1.13); C137(1.14)  LDD0573  [6]
 LDCM0257  AC138 HCT 116 C106(1.21); C130(1.35); C134(1.42); C137(1.35)  LDD0574  [6]
 LDCM0258  AC139 HCT 116 C106(1.23); C130(1.20); C134(1.18); C137(1.21)  LDD0575  [6]
 LDCM0259  AC14 HCT 116 C106(0.85); C130(0.91); C134(0.96); C137(0.99)  LDD0576  [6]
 LDCM0260  AC140 HCT 116 C106(1.29); C130(1.25); C134(1.27); C137(1.31)  LDD0577  [6]
 LDCM0261  AC141 HCT 116 C106(1.25); C130(1.12); C134(1.11); C137(1.16)  LDD0578  [6]
 LDCM0262  AC142 HCT 116 C106(1.18); C130(1.26); C134(1.23); C137(1.32)  LDD0579  [6]
 LDCM0263  AC143 HCT 116 C106(0.78); C46(0.83); C134(0.85); C130(0.85)  LDD0580  [6]
 LDCM0264  AC144 HCT 116 C46(0.67); C130(0.72); C134(0.72); C106(0.73)  LDD0581  [6]
 LDCM0265  AC145 HCT 116 C46(0.83); C106(0.88); C130(0.94); C134(0.96)  LDD0582  [6]
 LDCM0266  AC146 HCT 116 C46(0.65); C106(0.67); C130(0.86); C134(0.88)  LDD0583  [6]
 LDCM0267  AC147 HCT 116 C46(0.68); C106(0.79); C130(0.81); C134(0.85)  LDD0584  [6]
 LDCM0268  AC148 HCT 116 C46(0.49); C106(0.58); C130(0.77); C134(0.79)  LDD0585  [6]
 LDCM0269  AC149 HCT 116 C46(0.57); C106(0.67); C130(0.76); C134(0.79)  LDD0586  [6]
 LDCM0270  AC15 HCT 116 C134(0.89); C130(0.89); C137(0.92); C106(0.96)  LDD0587  [6]
 LDCM0271  AC150 HCT 116 C137(0.88); C134(0.96); C130(0.97); C106(0.97)  LDD0588  [6]
 LDCM0272  AC151 HCT 116 C46(0.80); C106(0.91); C130(0.95); C134(0.96)  LDD0589  [6]
 LDCM0273  AC152 HCT 116 C46(0.53); C106(0.73); C130(0.78); C134(0.80)  LDD0590  [6]
 LDCM0274  AC153 HCT 116 C46(0.37); C106(0.53); C130(0.76); C134(0.81)  LDD0591  [6]
 LDCM0621  AC154 HCT 116 C106(0.79); C130(0.83); C134(0.83); C137(0.89)  LDD2158  [6]
 LDCM0622  AC155 HCT 116 C106(0.71); C130(0.82); C134(0.82); C137(0.89)  LDD2159  [6]
 LDCM0623  AC156 HCT 116 C106(0.77); C130(0.88); C134(0.95); C137(1.01)  LDD2160  [6]
 LDCM0624  AC157 HCT 116 C106(0.79); C130(1.00); C134(1.00); C137(1.10)  LDD2161  [6]
 LDCM0276  AC17 HCT 116 C134(0.98); C137(0.98); C130(1.00); C27(1.06)  LDD0593  [6]
 LDCM0277  AC18 HCT 116 C130(0.85); C134(0.87); C137(0.89); C106(1.14)  LDD0594  [6]
 LDCM0278  AC19 HCT 116 C106(0.88); C134(0.92); C130(0.93); C137(0.93)  LDD0595  [6]
 LDCM0279  AC2 HCT 116 C137(0.90); C134(0.91); C130(0.96); C27(1.00)  LDD0596  [6]
 LDCM0280  AC20 HCT 116 C106(1.02); C134(1.05); C130(1.05); C27(1.07)  LDD0597  [6]
 LDCM0281  AC21 HCT 116 C137(0.92); C134(0.92); C106(0.92); C130(0.92)  LDD0598  [6]
 LDCM0282  AC22 HCT 116 C106(0.89); C27(1.09); C130(1.10); C134(1.11)  LDD0599  [6]
 LDCM0283  AC23 HCT 116 C130(0.94); C134(0.96); C137(1.01); C106(1.06)  LDD0600  [6]
 LDCM0284  AC24 HCT 116 C27(0.94); C106(0.99); C130(1.02); C134(1.02)  LDD0601  [6]
 LDCM0285  AC25 HCT 116 C134(0.86); C137(0.86); C130(0.90); C106(0.96)  LDD0602  [6]
 LDCM0286  AC26 HCT 116 C137(0.86); C134(0.88); C130(0.94); C106(0.99)  LDD0603  [6]
 LDCM0287  AC27 HCT 116 C134(0.81); C137(0.85); C130(0.89); C106(0.96)  LDD0604  [6]
 LDCM0288  AC28 HCT 116 C134(0.83); C130(0.85); C137(0.87); C106(0.96)  LDD0605  [6]
 LDCM0289  AC29 HCT 116 C134(0.80); C137(0.80); C130(0.87); C106(1.06)  LDD0606  [6]
 LDCM0290  AC3 HCT 116 C134(0.98); C137(0.99); C27(1.00); C130(1.01)  LDD0607  [6]
 LDCM0291  AC30 HCT 116 C134(0.81); C137(0.85); C130(0.87); C106(1.18)  LDD0608  [6]
 LDCM0292  AC31 HCT 116 C134(0.83); C137(0.86); C106(0.86); C130(0.88)  LDD0609  [6]
 LDCM0293  AC32 HCT 116 C134(0.75); C137(0.79); C130(0.83); C106(1.08)  LDD0610  [6]
 LDCM0294  AC33 HCT 116 C134(0.73); C137(0.78); C130(0.81); C106(0.84)  LDD0611  [6]
 LDCM0295  AC34 HCT 116 C134(0.65); C137(0.69); C130(0.75); C106(0.86)  LDD0612  [6]
 LDCM0296  AC35 HCT 116 C27(0.94); C130(1.13); C106(1.15); C134(1.16)  LDD0613  [6]
 LDCM0297  AC36 HCT 116 C27(1.05); C130(1.22); C134(1.24); C106(1.26)  LDD0614  [6]
 LDCM0298  AC37 HCT 116 C27(0.98); C106(1.01); C130(1.19); C134(1.22)  LDD0615  [6]
 LDCM0299  AC38 HCT 116 C106(0.99); C27(1.01); C130(1.09); C134(1.12)  LDD0616  [6]
 LDCM0300  AC39 HCT 116 C106(1.01); C134(1.02); C130(1.06); C137(1.06)  LDD0617  [6]
 LDCM0301  AC4 HCT 116 C134(0.94); C130(0.96); C137(0.96); C27(1.11)  LDD0618  [6]
 LDCM0302  AC40 HCT 116 C130(0.95); C134(1.00); C137(1.03); C106(1.07)  LDD0619  [6]
 LDCM0303  AC41 HCT 116 C134(1.09); C27(1.10); C130(1.13); C137(1.16)  LDD0620  [6]
 LDCM0304  AC42 HCT 116 C134(1.01); C130(1.02); C137(1.04); C106(1.10)  LDD0621  [6]
 LDCM0305  AC43 HCT 116 C130(0.91); C134(0.91); C137(0.94); C106(1.05)  LDD0622  [6]
 LDCM0306  AC44 HCT 116 C106(1.07); C27(1.09); C130(1.11); C137(1.17)  LDD0623  [6]
 LDCM0307  AC45 HCT 116 C130(0.93); C134(0.95); C137(0.98); C46(1.04)  LDD0624  [6]
 LDCM0308  AC46 HCT 116 C106(0.71); C46(0.81); C134(0.96); C137(0.96)  LDD0625  [6]
 LDCM0309  AC47 HCT 116 C106(0.84); C46(0.86); C137(1.00); C130(1.03)  LDD0626  [6]
 LDCM0310  AC48 HCT 116 C106(0.66); C46(0.80); C137(0.91); C134(0.94)  LDD0627  [6]
 LDCM0311  AC49 HCT 116 C46(0.60); C106(0.72); C137(0.81); C134(0.82)  LDD0628  [6]
 LDCM0312  AC5 HCT 116 C137(1.00); C134(1.02); C130(1.02); C106(1.03)  LDD0629  [6]
 LDCM0313  AC50 HCT 116 C46(0.58); C106(0.63); C137(0.81); C134(0.82)  LDD0630  [6]
 LDCM0314  AC51 HCT 116 C106(0.86); C46(0.97); C27(1.04); C130(1.18)  LDD0631  [6]
 LDCM0315  AC52 HCT 116 C106(0.81); C137(0.97); C134(0.99); C46(1.00)  LDD0632  [6]
 LDCM0316  AC53 HCT 116 C106(0.72); C46(0.77); C130(0.88); C137(0.89)  LDD0633  [6]
 LDCM0317  AC54 HCT 116 C46(0.75); C106(0.75); C130(0.86); C134(0.90)  LDD0634  [6]
 LDCM0318  AC55 HCT 116 C46(0.54); C106(0.61); C130(0.85); C134(0.86)  LDD0635  [6]
 LDCM0319  AC56 HCT 116 C46(0.42); C106(0.48); C134(0.78); C130(0.78)  LDD0636  [6]
 LDCM0320  AC57 HCT 116 C106(0.73); C46(0.77); C134(0.79); C130(0.82)  LDD0637  [6]
 LDCM0321  AC58 HCT 116 C46(0.51); C106(0.65); C134(0.82); C130(0.83)  LDD0638  [6]
 LDCM0322  AC59 HCT 116 C106(0.74); C134(0.83); C46(0.84); C130(0.84)  LDD0639  [6]
 LDCM0323  AC6 HCT 116 C130(0.93); C134(0.97); C137(0.99); C27(1.24)  LDD0640  [6]
 LDCM0324  AC60 HCT 116 C106(0.67); C134(0.72); C46(0.73); C137(0.76)  LDD0641  [6]
 LDCM0325  AC61 HCT 116 C46(0.72); C106(0.73); C134(0.79); C130(0.81)  LDD0642  [6]
 LDCM0326  AC62 HCT 116 C46(0.64); C106(0.72); C134(0.80); C130(0.81)  LDD0643  [6]
 LDCM0327  AC63 HCT 116 C46(0.75); C106(0.79); C134(0.80); C130(0.83)  LDD0644  [6]
 LDCM0328  AC64 HCT 116 C46(0.60); C106(0.66); C134(0.76); C130(0.78)  LDD0645  [6]
 LDCM0329  AC65 HCT 116 C106(0.89); C130(0.93); C134(0.93); C46(0.95)  LDD0646  [6]
 LDCM0330  AC66 HCT 116 C106(0.85); C134(0.94); C130(0.95); C137(0.97)  LDD0647  [6]
 LDCM0331  AC67 HCT 116 C46(0.47); C106(0.66); C134(0.72); C130(0.74)  LDD0648  [6]
 LDCM0332  AC68 HCT 116 C130(0.86); C106(0.88); C137(0.91); C134(0.92)  LDD0649  [6]
 LDCM0333  AC69 HCT 116 C106(0.70); C130(0.75); C134(0.78); C137(0.80)  LDD0650  [6]
 LDCM0334  AC7 HCT 116 C106(1.01); C130(1.12); C134(1.15); C27(1.24)  LDD0651  [6]
 LDCM0335  AC70 HCT 116 C134(0.73); C130(0.75); C137(0.77); C106(0.83)  LDD0652  [6]
 LDCM0336  AC71 HCT 116 C130(0.89); C137(0.94); C134(0.94); C106(0.99)  LDD0653  [6]
 LDCM0337  AC72 HCT 116 C134(0.81); C130(0.84); C137(0.84); C106(0.91)  LDD0654  [6]
 LDCM0338  AC73 HCT 116 C130(0.69); C137(0.76); C134(0.76); C106(0.79)  LDD0655  [6]
 LDCM0339  AC74 HCT 116 C130(0.72); C134(0.77); C106(0.78); C137(0.80)  LDD0656  [6]
 LDCM0340  AC75 HCT 116 C106(0.63); C137(0.72); C130(0.73); C134(0.75)  LDD0657  [6]
 LDCM0341  AC76 HCT 116 C106(0.80); C137(0.85); C134(0.85); C130(0.87)  LDD0658  [6]
 LDCM0342  AC77 HCT 116 C106(0.87); C130(0.89); C46(0.93); C137(0.93)  LDD0659  [6]
 LDCM0343  AC78 HCT 116 C106(0.82); C130(0.82); C137(0.83); C134(0.85)  LDD0660  [6]
 LDCM0344  AC79 HCT 116 C130(0.88); C137(0.94); C134(0.96); C27(1.07)  LDD0661  [6]
 LDCM0345  AC8 HCT 116 C106(0.95); C130(0.97); C134(1.00); C137(1.06)  LDD0662  [6]
 LDCM0346  AC80 HCT 116 C130(0.79); C137(0.84); C134(0.86); C106(0.93)  LDD0663  [6]
 LDCM0347  AC81 HCT 116 C130(0.86); C137(0.92); C134(0.94); C106(1.11)  LDD0664  [6]
 LDCM0348  AC82 HCT 116 C130(0.67); C106(0.69); C137(0.72); C134(0.76)  LDD0665  [6]
 LDCM0349  AC83 HCT 116 C134(0.78); C130(0.81); C137(0.96); C106(1.03)  LDD0666  [6]
 LDCM0350  AC84 HCT 116 C130(0.76); C134(0.76); C137(0.87); C106(1.07)  LDD0667  [6]
 LDCM0351  AC85 HCT 116 C130(0.84); C134(0.85); C137(0.97); C106(1.14)  LDD0668  [6]
 LDCM0352  AC86 HCT 116 C134(0.96); C137(0.97); C130(1.08); C27(1.11)  LDD0669  [6]
 LDCM0353  AC87 HCT 116 C130(0.92); C134(0.92); C137(0.99); C106(0.99)  LDD0670  [6]
 LDCM0354  AC88 HCT 116 C134(1.00); C137(1.04); C130(1.06); C27(1.08)  LDD0671  [6]
 LDCM0355  AC89 HCT 116 C134(0.78); C130(0.86); C137(0.97); C106(1.04)  LDD0672  [6]
 LDCM0357  AC90 HCT 116 C27(1.01); C137(1.05); C134(1.22); C130(1.31)  LDD0674  [6]
 LDCM0358  AC91 HCT 116 C134(0.79); C130(0.87); C137(0.98); C106(0.99)  LDD0675  [6]
 LDCM0359  AC92 HCT 116 C134(0.83); C130(0.90); C106(1.02); C137(1.02)  LDD0676  [6]
 LDCM0360  AC93 HCT 116 C134(0.82); C130(0.88); C137(0.94); C106(1.12)  LDD0677  [6]
 LDCM0361  AC94 HCT 116 C134(0.82); C130(0.90); C27(1.07); C137(1.09)  LDD0678  [6]
 LDCM0362  AC95 HCT 116 C134(0.85); C130(0.89); C137(0.99); C106(1.03)  LDD0679  [6]
 LDCM0363  AC96 HCT 116 C134(0.76); C130(0.76); C137(0.96); C106(1.08)  LDD0680  [6]
 LDCM0364  AC97 HCT 116 C134(0.80); C130(0.83); C137(0.94); C106(1.09)  LDD0681  [6]
 LDCM0365  AC98 HCT 116 C130(0.50); C137(0.52); C134(0.53); C106(0.56)  LDD0682  [6]
 LDCM0366  AC99 HCT 116 C137(0.71); C130(0.75); C134(0.77); C106(0.88)  LDD0683  [6]
 LDCM0545  Acetamide MDA-MB-231 C27(1.88); C106(0.75)  LDD2138  [4]
 LDCM0520  AKOS000195272 MDA-MB-231 C27(1.01); C130(0.91)  LDD2113  [4]
 LDCM0248  AKOS034007472 HCT 116 C106(0.94); C130(1.01); C134(1.06); C137(1.04)  LDD0565  [6]
 LDCM0356  AKOS034007680 HCT 116 C106(0.97); C130(1.02); C134(1.07); C137(1.10)  LDD0673  [6]
 LDCM0275  AKOS034007705 HCT 116 C134(0.77); C130(0.79); C137(0.80); C106(1.02)  LDD0592  [6]
 LDCM0020  ARS-1620 HCC44 C27(1.31); C106(0.95); C130(0.88); C134(0.88)  LDD0078  [6]
 LDCM0498  BS-3668 MDA-MB-231 C106(0.56)  LDD2091  [4]
 LDCM0108  Chloroacetamide HeLa H111(0.00); C137(0.00)  LDD0222  [14]
 LDCM0632  CL-Sc Hep-G2 C27(1.53)  LDD2227  [10]
 LDCM0367  CL1 HCT 116 C130(1.09); C134(1.10); C137(1.13); C27(1.21)  LDD0684  [6]
 LDCM0368  CL10 HCT 116 C134(0.90); C106(0.91); C137(0.92); C130(0.94)  LDD0685  [6]
 LDCM0369  CL100 HCT 116 C134(0.89); C130(0.90); C137(0.93); C106(0.95)  LDD0686  [6]
 LDCM0370  CL101 HCT 116 C130(0.99); C134(1.01); C137(1.05); C27(1.14)  LDD0687  [6]
 LDCM0371  CL102 HCT 116 C106(1.07); C130(1.13); C137(1.17); C134(1.17)  LDD0688  [6]
 LDCM0372  CL103 HCT 116 C106(0.95); C27(1.06); C130(1.09); C134(1.19)  LDD0689  [6]
 LDCM0373  CL104 HCT 116 C130(0.91); C134(0.93); C137(0.99); C27(1.01)  LDD0690  [6]
 LDCM0374  CL105 HCT 116 C130(0.87); C134(0.88); C137(0.91); C106(1.10)  LDD0691  [6]
 LDCM0375  CL106 HCT 116 C130(0.74); C134(0.74); C137(0.77); C106(1.02)  LDD0692  [6]
 LDCM0376  CL107 HCT 116 C137(0.83); C134(0.86); C130(0.87); C106(0.96)  LDD0693  [6]
 LDCM0377  CL108 HCT 116 C134(0.82); C137(0.84); C130(0.85); C106(1.20)  LDD0694  [6]
 LDCM0378  CL109 HCT 116 C130(0.89); C134(0.90); C137(0.92); C106(1.01)  LDD0695  [6]
 LDCM0379  CL11 HCT 116 C134(0.86); C137(0.88); C130(0.88); C106(0.92)  LDD0696  [6]
 LDCM0380  CL110 HCT 116 C130(0.82); C134(0.82); C137(0.83); C106(0.98)  LDD0697  [6]
 LDCM0381  CL111 HCT 116 C134(0.83); C137(0.84); C130(0.85); C106(1.07)  LDD0698  [6]
 LDCM0382  CL112 HCT 116 C134(0.86); C130(0.95); C137(0.96); C27(1.02)  LDD0699  [6]
 LDCM0383  CL113 HCT 116 C134(0.75); C137(0.76); C130(0.82); C106(1.08)  LDD0700  [6]
 LDCM0384  CL114 HCT 116 C137(0.84); C134(0.88); C130(0.96); C106(1.05)  LDD0701  [6]
 LDCM0385  CL115 HCT 116 C134(0.87); C130(0.88); C137(0.89); C106(0.98)  LDD0702  [6]
 LDCM0386  CL116 HCT 116 C137(0.85); C134(0.86); C106(0.87); C130(0.93)  LDD0703  [6]
 LDCM0387  CL117 HCT 116 C46(0.81); C130(0.81); C134(0.85); C137(0.87)  LDD0704  [6]
 LDCM0388  CL118 HCT 116 C130(1.04); C134(1.04); C137(1.07); C27(1.21)  LDD0705  [6]
 LDCM0389  CL119 HCT 116 C130(0.96); C134(0.96); C137(1.01); C106(1.02)  LDD0706  [6]
 LDCM0390  CL12 HCT 116 C106(0.83); C137(0.93); C130(0.97); C134(0.98)  LDD0707  [6]
 LDCM0391  CL120 HCT 116 C27(1.09); C134(1.12); C137(1.16); C130(1.18)  LDD0708  [6]
 LDCM0392  CL121 HCT 116 C27(0.92); C46(0.97); C106(1.14); C130(1.54)  LDD0709  [6]
 LDCM0393  CL122 HCT 116 C106(0.65); C46(0.70); C137(0.83); C134(0.84)  LDD0710  [6]
 LDCM0394  CL123 HCT 116 C46(0.95); C130(0.95); C134(0.96); C106(0.98)  LDD0711  [6]
 LDCM0395  CL124 HCT 116 C46(0.67); C106(0.73); C134(0.82); C137(0.84)  LDD0712  [6]
 LDCM0396  CL125 HCT 116 C134(0.87); C130(0.98); C137(0.99); C27(1.08)  LDD0713  [6]
 LDCM0397  CL126 HCT 116 C130(0.99); C134(0.99); C106(1.02); C137(1.03)  LDD0714  [6]
 LDCM0398  CL127 HCT 116 C134(0.91); C130(0.92); C106(0.94); C46(0.94)  LDD0715  [6]
 LDCM0399  CL128 HCT 116 C46(0.62); C106(0.85); C137(0.86); C134(0.87)  LDD0716  [6]
 LDCM0400  CL13 HCT 116 C130(0.85); C134(0.86); C137(0.86); C106(0.87)  LDD0717  [6]
 LDCM0401  CL14 HCT 116 C137(0.97); C130(1.01); C134(1.03); C106(1.11)  LDD0718  [6]
 LDCM0402  CL15 HCT 116 C106(0.90); C130(1.00); C134(1.02); C137(1.06)  LDD0719  [6]
 LDCM0403  CL16 HCT 116 C130(0.99); C27(1.05); C134(1.07); C137(1.09)  LDD0720  [6]
 LDCM0404  CL17 HCT 116 C137(0.92); C134(0.96); C130(0.96); C106(1.05)  LDD0721  [6]
 LDCM0405  CL18 HCT 116 C130(0.76); C106(0.79); C137(0.79); C134(0.82)  LDD0722  [6]
 LDCM0406  CL19 HCT 116 C106(0.71); C130(0.88); C137(0.88); C134(0.90)  LDD0723  [6]
 LDCM0407  CL2 HCT 116 C106(1.02); C27(1.08); C130(1.10); C134(1.13)  LDD0724  [6]
 LDCM0408  CL20 HCT 116 C137(0.90); C130(0.90); C106(0.90); C134(0.92)  LDD0725  [6]
 LDCM0409  CL21 HCT 116 C130(0.78); C137(0.81); C134(0.84); C106(0.86)  LDD0726  [6]
 LDCM0410  CL22 HCT 116 C106(0.55); C130(0.88); C137(0.88); C134(0.89)  LDD0727  [6]
 LDCM0411  CL23 HCT 116 C106(0.84); C137(0.90); C134(0.93); C130(0.93)  LDD0728  [6]
 LDCM0412  CL24 HCT 116 C130(0.79); C137(0.80); C134(0.82); C106(0.85)  LDD0729  [6]
 LDCM0413  CL25 HCT 116 C106(2.64); C130(0.92); C134(0.94); C137(0.88)  LDD0730  [6]
 LDCM0414  CL26 HCT 116 C106(0.90); C130(0.92); C134(0.90); C137(0.89)  LDD0731  [6]
 LDCM0415  CL27 HCT 116 C106(0.77); C130(0.94); C134(1.01); C137(1.00)  LDD0732  [6]
 LDCM0416  CL28 HCT 116 C106(1.20); C130(0.80); C134(0.83); C137(0.82)  LDD0733  [6]
 LDCM0417  CL29 HCT 116 C106(0.81); C130(0.85); C134(0.87); C137(0.83)  LDD0734  [6]
 LDCM0418  CL3 HCT 116 C106(1.12); C130(1.10); C134(1.06); C137(1.10)  LDD0735  [6]
 LDCM0419  CL30 HCT 116 C106(1.16); C130(0.92); C134(0.96); C137(0.93)  LDD0736  [6]
 LDCM0420  CL31 HCT 116 C106(0.94); C130(0.92); C134(0.86); C137(0.83)  LDD0737  [6]
 LDCM0421  CL32 HCT 116 C106(0.89); C130(0.80); C134(0.79); C137(0.75)  LDD0738  [6]
 LDCM0422  CL33 HCT 116 C106(1.00); C130(0.84); C134(0.75); C137(0.73)  LDD0739  [6]
 LDCM0423  CL34 HCT 116 C106(0.80); C130(0.76); C134(0.72); C137(0.72)  LDD0740  [6]
 LDCM0424  CL35 HCT 116 C106(0.77); C130(0.77); C134(0.74); C137(0.70)  LDD0741  [6]
 LDCM0425  CL36 HCT 116 C106(1.08); C130(0.84); C134(0.79); C137(0.78)  LDD0742  [6]
 LDCM0426  CL37 HCT 116 C106(0.70); C130(0.75); C134(0.72); C137(0.71)  LDD0743  [6]
 LDCM0428  CL39 HCT 116 C106(0.95); C130(0.79); C134(0.74); C137(0.74)  LDD0745  [6]
 LDCM0429  CL4 HCT 116 C106(1.35); C130(1.08); C134(1.15); C137(1.13)  LDD0746  [6]
 LDCM0430  CL40 HCT 116 C106(1.06); C130(0.83); C134(0.77); C137(0.76)  LDD0747  [6]
 LDCM0431  CL41 HCT 116 C106(0.95); C130(0.92); C134(0.91); C137(0.86)  LDD0748  [6]
 LDCM0432  CL42 HCT 116 C106(0.72); C130(0.78); C134(0.75); C137(0.73)  LDD0749  [6]
 LDCM0433  CL43 HCT 116 C106(0.86); C130(0.74); C134(0.71); C137(0.68)  LDD0750  [6]
 LDCM0434  CL44 HCT 116 C106(0.83); C130(0.81); C134(0.75); C137(0.75)  LDD0751  [6]
 LDCM0435  CL45 HCT 116 C106(0.92); C130(0.78); C134(0.76); C137(0.74)  LDD0752  [6]
 LDCM0436  CL46 HCT 116 C106(1.08); C130(1.28); C134(1.26); C137(1.28)  LDD0753  [6]
 LDCM0437  CL47 HCT 116 C106(1.12); C130(1.29); C134(1.21); C137(1.25)  LDD0754  [6]
 LDCM0438  CL48 HCT 116 C106(1.17); C130(1.22); C134(1.10); C137(1.11)  LDD0755  [6]
 LDCM0439  CL49 HCT 116 C106(1.06); C130(1.10); C134(1.02); C137(0.99)  LDD0756  [6]
 LDCM0440  CL5 HCT 116 C106(0.87); C130(1.03); C134(1.04); C137(1.06)  LDD0757  [6]
 LDCM0441  CL50 HCT 116 C106(1.03); C130(1.30); C134(1.25); C137(1.32)  LDD0758  [6]
 LDCM0442  CL51 HCT 116 C106(1.12); C130(1.27); C134(1.25); C137(1.27)  LDD0759  [6]
 LDCM0443  CL52 HCT 116 C106(1.09); C130(1.31); C134(1.30); C137(1.32)  LDD0760  [6]
 LDCM0444  CL53 HCT 116 C106(0.90); C130(1.16); C134(1.13); C137(1.18)  LDD0761  [6]
 LDCM0445  CL54 HCT 116 C106(1.36); C130(1.17); C134(1.28); C137(1.37)  LDD0762  [6]
 LDCM0446  CL55 HCT 116 C106(1.00); C130(1.35); C134(1.23); C137(1.32)  LDD0763  [6]
 LDCM0447  CL56 HCT 116 C106(1.10); C130(1.11); C134(1.09); C137(1.11)  LDD0764  [6]
 LDCM0448  CL57 HCT 116 C106(1.03); C130(1.30); C134(1.32); C137(1.42)  LDD0765  [6]
 LDCM0449  CL58 HCT 116 C106(1.02); C130(1.20); C134(1.22); C137(1.21)  LDD0766  [6]
 LDCM0450  CL59 HCT 116 C106(1.06); C130(1.15); C134(1.15); C137(1.14)  LDD0767  [6]
 LDCM0451  CL6 HCT 116 C106(0.86); C130(0.91); C134(0.92); C137(0.94)  LDD0768  [6]
 LDCM0452  CL60 HCT 116 C106(1.09); C130(1.17); C134(1.13); C137(1.14)  LDD0769  [6]
 LDCM0453  CL61 HCT 116 C106(1.05); C130(0.99); C134(1.01); C137(1.00)  LDD0770  [6]
 LDCM0454  CL62 HCT 116 C106(1.23); C130(1.00); C134(1.00); C137(1.02)  LDD0771  [6]
 LDCM0455  CL63 HCT 116 C106(1.37); C130(0.95); C134(0.94); C137(0.98)  LDD0772  [6]
 LDCM0456  CL64 HCT 116 C106(1.15); C130(0.87); C134(0.86); C137(0.91)  LDD0773  [6]
 LDCM0457  CL65 HCT 116 C106(1.07); C130(1.02); C134(0.96); C137(0.99)  LDD0774  [6]
 LDCM0458  CL66 HCT 116 C106(1.14); C130(0.84); C134(0.86); C137(0.88)  LDD0775  [6]
 LDCM0459  CL67 HCT 116 C106(0.97); C130(0.88); C134(0.87); C137(0.87)  LDD0776  [6]
 LDCM0460  CL68 HCT 116 C106(0.96); C130(0.92); C134(0.89); C137(0.95)  LDD0777  [6]
 LDCM0461  CL69 HCT 116 C106(1.27); C130(0.96); C134(0.91); C137(0.99)  LDD0778  [6]
 LDCM0462  CL7 HCT 116 C106(0.98); C130(0.93); C134(0.93); C137(0.91)  LDD0779  [6]
 LDCM0463  CL70 HCT 116 C106(1.24); C130(0.87); C134(0.85); C137(0.89)  LDD0780  [6]
 LDCM0464  CL71 HCT 116 C106(1.30); C130(0.89); C134(0.87); C137(0.90)  LDD0781  [6]
 LDCM0465  CL72 HCT 116 C106(1.06); C130(1.03); C134(0.99); C137(1.04)  LDD0782  [6]
 LDCM0466  CL73 HCT 116 C106(1.05); C130(0.83); C134(0.81); C137(0.86)  LDD0783  [6]
 LDCM0467  CL74 HCT 116 C106(1.09); C130(0.90); C134(0.92); C137(0.96)  LDD0784  [6]
 LDCM0469  CL76 HCT 116 C106(0.78); C130(0.83); C134(0.88); C137(0.89)  LDD0786  [6]
 LDCM0470  CL77 HCT 116 C106(1.05); C130(0.94); C134(0.90); C137(0.92)  LDD0787  [6]
 LDCM0471  CL78 HCT 116 C106(1.11); C130(1.01); C134(0.92); C137(0.92)  LDD0788  [6]
 LDCM0472  CL79 HCT 116 C106(1.03); C130(0.86); C134(0.89); C137(0.92)  LDD0789  [6]
 LDCM0473  CL8 HCT 116 C106(0.91); C130(0.93); C134(0.94); C137(0.93)  LDD0790  [6]
 LDCM0474  CL80 HCT 116 C106(0.78); C130(0.88); C134(0.93); C137(0.92)  LDD0791  [6]
 LDCM0475  CL81 HCT 116 C106(1.09); C130(0.93); C134(0.91); C137(0.94)  LDD0792  [6]
 LDCM0476  CL82 HCT 116 C106(1.07); C130(0.85); C134(0.84); C137(0.93)  LDD0793  [6]
 LDCM0477  CL83 HCT 116 C106(1.25); C130(0.89); C134(0.84); C137(0.83)  LDD0794  [6]
 LDCM0478  CL84 HCT 116 C106(0.84); C130(0.76); C134(0.76); C137(0.76)  LDD0795  [6]
 LDCM0479  CL85 HCT 116 C106(1.01); C130(0.93); C134(0.80); C137(0.79)  LDD0796  [6]
 LDCM0480  CL86 HCT 116 C106(1.05); C130(0.99); C134(0.90); C137(0.89)  LDD0797  [6]
 LDCM0481  CL87 HCT 116 C106(1.04); C130(0.92); C134(0.94); C137(0.92)  LDD0798  [6]
 LDCM0482  CL88 HCT 116 C106(0.89); C130(0.79); C134(0.82); C137(0.84)  LDD0799  [6]
 LDCM0483  CL89 HCT 116 C106(0.75); C130(0.80); C134(0.81); C137(0.85)  LDD0800  [6]
 LDCM0484  CL9 HCT 116 C106(0.98); C130(0.98); C134(0.94); C137(0.96)  LDD0801  [6]
 LDCM0485  CL90 HCT 116 C106(1.35); C130(0.99); C134(0.92); C137(0.93)  LDD0802  [6]
 LDCM0486  CL91 HCT 116 C106(0.90); C130(1.02); C134(0.93); C137(0.93)  LDD0803  [6]
 LDCM0487  CL92 HCT 116 C106(1.11); C130(0.98); C134(0.97); C137(0.98)  LDD0804  [6]
 LDCM0488  CL93 HCT 116 C106(1.01); C130(1.03); C134(0.98); C137(1.04)  LDD0805  [6]
 LDCM0489  CL94 HCT 116 C106(0.86); C130(0.91); C134(0.88); C137(0.90)  LDD0806  [6]
 LDCM0490  CL95 HCT 116 C106(1.12); C130(0.90); C134(0.87); C137(0.88)  LDD0807  [6]
 LDCM0491  CL96 HCT 116 C106(1.08); C130(0.87); C134(0.85); C137(0.87)  LDD0808  [6]
 LDCM0492  CL97 HCT 116 C106(1.20); C130(0.93); C134(0.92); C137(0.95)  LDD0809  [6]
 LDCM0493  CL98 HCT 116 C106(1.02); C130(0.95); C134(0.94); C137(0.93)  LDD0810  [6]
 LDCM0494  CL99 HCT 116 C106(1.05); C130(0.93); C134(0.89); C137(0.93)  LDD0811  [6]
 LDCM0033  Curcusone1d MCF-7 2.05  LDD0188  [5]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C137(27.51); C27(18.68); C130(15.97); C134(9.23)  LDD1702  [4]
 LDCM0202  EV-93 T cell C27(4.61)  LDD0514  [16]
 LDCM0625  F8 Ramos C46(1.56); C106(0.56)  LDD2187  [17]
 LDCM0572  Fragment10 Ramos C106(2.45)  LDD2189  [17]
 LDCM0573  Fragment11 Ramos C46(0.73); C106(2.71)  LDD2190  [17]
 LDCM0574  Fragment12 Ramos C106(5.14)  LDD2191  [17]
 LDCM0575  Fragment13 Ramos C27(0.53); C106(1.82)  LDD2192  [17]
 LDCM0576  Fragment14 Ramos C106(5.28)  LDD2193  [17]
 LDCM0579  Fragment20 Ramos C106(5.86)  LDD2194  [17]
 LDCM0580  Fragment21 Ramos C27(0.59); C106(1.25)  LDD2195  [17]
 LDCM0582  Fragment23 Ramos C27(0.44); C106(0.54)  LDD2196  [17]
 LDCM0578  Fragment27 Ramos C27(1.25); C106(1.03)  LDD2197  [17]
 LDCM0586  Fragment28 Ramos C27(1.45); C46(0.87); C106(1.96)  LDD2198  [17]
 LDCM0588  Fragment30 Ramos C106(1.46)  LDD2199  [17]
 LDCM0589  Fragment31 Ramos C27(0.50); C106(1.44)  LDD2200  [17]
 LDCM0590  Fragment32 Ramos C106(2.43)  LDD2201  [17]
 LDCM0468  Fragment33 HCT 116 C106(1.13); C130(0.91); C134(0.86); C137(0.93)  LDD0785  [6]
 LDCM0596  Fragment38 Ramos C27(0.31); C106(2.23)  LDD2203  [17]
 LDCM0566  Fragment4 Ramos C27(0.23); C46(1.81); C106(1.45)  LDD2184  [17]
 LDCM0427  Fragment51 HCT 116 C106(0.89); C130(0.76); C134(0.73); C137(0.69)  LDD0744  [6]
 LDCM0610  Fragment52 Ramos C27(1.29)  LDD2204  [17]
 LDCM0614  Fragment56 Ramos C27(0.81); C106(1.56)  LDD2205  [17]
 LDCM0569  Fragment7 Ramos C106(1.45)  LDD2186  [17]
 LDCM0571  Fragment9 Ramos C106(4.83)  LDD2188  [17]
 LDCM0015  HNE MDA-MB-231 C27(1.12)  LDD0346  [17]
 LDCM0107  IAA HeLa C137(0.00); H111(0.00)  LDD0221  [14]
 LDCM0179  JZ128 PC-3 C134(0.00); C27(0.00)  LDD0462  [3]
 LDCM0022  KB02 Ramos C106(2.23)  LDD2182  [17]
 LDCM0023  KB03 Jurkat C27(190.97)  LDD0209  [18]
 LDCM0024  KB05 COLO792 C46(2.98); C106(3.64)  LDD3310  [19]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C27(1.97)  LDD2102  [4]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C27(1.34)  LDD2121  [4]
 LDCM0109  NEM HeLa N.A.  LDD0223  [14]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C27(0.78); C106(0.57)  LDD2089  [4]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C27(1.42); C106(1.16)  LDD2090  [4]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C134(0.83); C130(0.80)  LDD2092  [4]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C27(1.42)  LDD2093  [4]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C27(1.48); C134(1.06); C130(0.87)  LDD2094  [4]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C27(0.86); C106(1.10)  LDD2097  [4]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C27(1.09); C134(0.86); C130(2.89)  LDD2098  [4]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C27(0.95); C106(1.02); C46(1.53)  LDD2099  [4]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C134(0.92); C130(1.35)  LDD2100  [4]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C27(1.27); C106(1.29); C130(0.65)  LDD2101  [4]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C134(1.12); C130(1.03); C137(1.12)  LDD2104  [4]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C27(2.01); C106(1.02); C134(1.62); C130(1.56)  LDD2105  [4]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C27(0.82); C106(1.10); C46(1.51)  LDD2107  [4]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C134(0.80); C130(0.87); C137(0.86)  LDD2108  [4]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C106(1.15); C46(1.56)  LDD2109  [4]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C106(0.89)  LDD2111  [4]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C134(1.04); C130(0.69)  LDD2114  [4]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C27(0.86)  LDD2115  [4]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C27(1.94); C106(1.68); C46(1.27)  LDD2119  [4]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C27(0.88); C106(0.57); C130(0.85)  LDD2120  [4]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C27(1.02); C106(0.87)  LDD2123  [4]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C27(0.93); C106(0.65); C46(1.20)  LDD2125  [4]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C27(0.81); C106(0.92)  LDD2127  [4]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C27(1.12); C130(1.55)  LDD2128  [4]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C27(1.05); C106(0.94)  LDD2133  [4]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C27(0.54); C130(0.66)  LDD2134  [4]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C27(1.04); C106(1.01)  LDD2135  [4]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C27(0.94); C106(1.40); C46(2.45)  LDD2136  [4]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C27(0.97)  LDD2137  [4]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C27(0.75)  LDD1700  [4]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C27(0.89); C106(0.83)  LDD2140  [4]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C106(0.39); C134(0.58); C130(0.77); C46(0.97)  LDD2141  [4]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C27(0.93); C130(1.02)  LDD2143  [4]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C106(1.79)  LDD2144  [4]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C27(0.95); C106(0.82)  LDD2146  [4]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C27(1.82)  LDD2147  [4]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C27(0.86); C106(0.67)  LDD2148  [4]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C27(0.68); C106(0.42)  LDD2150  [4]
 LDCM0131  RA190 MM1.R C27(3.05); C106(1.36)  LDD0304  [20]
 LDCM0021  THZ1 HCT 116 C27(1.13); C130(1.51); C134(1.51); C137(1.51)  LDD2173  [6]

References

1 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
2 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
3 A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification. J Am Chem Soc. 2019 Jan 9;141(1):191-203. doi: 10.1021/jacs.8b07911. Epub 2018 Dec 20.
4 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
5 Total Synthesis and Target Identification of the Curcusone Diterpenes. J Am Chem Soc. 2021 Mar 24;143(11):4379-4386. doi: 10.1021/jacs.1c00557. Epub 2021 Mar 11.
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
8 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
9 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
10 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
11 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
12 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
13 Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. Mol Cell Proteomics. 2023 Jan;22(1):100455. doi: 10.1016/j.mcpro.2022.100455. Epub 2022 Nov 24.
Mass spectrometry data entry: PXD036569
14 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
15 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
16 An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.
17 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
18 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.
19 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
20 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.