Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0540
Competitor Name
Nucleophilic fragment 35
Synonyms
N-(3-(tert-butyl)isoxazol-5-yl)-2-cyanoacetamide
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 207.23
Lipid-water partition coefficient (xlogp) 2
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C10H13N3O2
IUPAC Name
N-(3-tert-butyl-1,2-oxazol-5-yl)-2-cyanoacetamide
Canonical SMILES
CC(C)(C)C1=NOC(=C1)NC(=O)CC#N
InChI
InChI=1S/C10H13N3O2/c1-10(2,3)7-6-9(15-13-7)12-8(14)4-5-11/h6H,4H2,1-3H3,(H,12,14)
InChIKey
IQFUFCGUMXOFLG-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
BTD
 Probe Info  		5 mM Human breast adenocarcinoma cell lysate (MDA-MB-231) [1]

Target(s) List of this Competitor

374 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) LDTP02356 0.51  LDD2133 
2',5'-phosphodiesterase 12 (PDE12) LDTP07447 0.54  LDD2133 
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (DECR1) LDTP06612 0.53  LDD2133 
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (GCAT) LDTP01268 0.69  LDD2133 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 0.52; 0.45  LDD2133 
2-iminobutanoate/2-iminopropanoate deaminase (RIDA) LDTP04529 0.53  LDD2133 
26S proteasome non-ATPase regulatory subunit 1 (PSMD1) LDTP10869 0.78; 1.02  LDD2133 
26S proteasome non-ATPase regulatory subunit 12 (PSMD12) LDTP00224 0.97  LDD2133 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 0.36; 0.54  LDD2133 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 0.99; 0.78; 0.54  LDD2133 
26S proteasome non-ATPase regulatory subunit 4 (PSMD4) LDTP04655 0.67  LDD2133 
26S proteasome non-ATPase regulatory subunit 9 (PSMD9) LDTP00225 0.68  LDD2133 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 0.50  LDD2133 
26S proteasome regulatory subunit 6A (PSMC3) LDTP02933 0.59  LDD2133 
26S proteasome regulatory subunit 7 (PSMC2) LDTP03797 0.72; 0.62  LDD2133 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 0.72; 0.68  LDD2133 
3-ketoacyl-CoA thiolase, mitochondrial (ACAA2) LDTP03998 0.38  LDD2133 
3-ketoacyl-CoA thiolase, peroxisomal (ACAA1) LDTP02329 0.75  LDD2133 
4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) LDTP04232 0.67; 0.87  LDD2133 
6-phosphogluconate dehydrogenase, decarboxylating (PGD) LDTP04499 0.45  LDD2133 
6-phosphogluconolactonase (PGLS) LDTP14535 0.78  LDD2133 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 0.39  LDD2133 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 0.62; 0.98; 0.63  LDD2133 
Actin, cytoplasmic 2 (ACTG1) LDTP05059 0.82  LDD2133 
Acyl-coenzyme A thioesterase 9, mitochondrial (ACOT9) LDTP16274 0.59  LDD2133 
Acyl-protein thioesterase 2 (LYPLA2) LDTP01573 0.92  LDD2133 
Acylamino-acid-releasing enzyme (APEH) LDTP02693 0.54  LDD2133 
Acylpyruvase FAHD1, mitochondrial (FAHD1) LDTP07540 1.36  LDD2133 
Adenosine 5'-monophosphoramidase HINT1 (HINT1) LDTP04306 0.55  LDD2133 
Adenosylhomocysteinase (AHCY) LDTP03242 0.58; 0.55  LDD2133 
Adenylosuccinate lyase (ADSL) LDTP03551 0.83; 0.54; 0.48  LDD2133 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 0.48  LDD2133 
Alcohol dehydrogenase class-3 (ADH5) LDTP02587 0.59  LDD2133 
Aldehyde dehydrogenase 1A1 (ALDH1A1) LDTP01767 0.50  LDD2133 
Aldehyde oxidase (AOX1) LDTP05483 0.97  LDD2133 
Aldo-keto reductase family 1 member B1 (AKR1B1) LDTP02765 0.40; 0.66; 0.65  LDD2133 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 1.00; 0.55; 0.64  LDD2133 
Alpha-1,2-mannosyltransferase ALG9 (ALG9) LDTP12002 0.54  LDD2133 
Alpha-enolase (ENO1) LDTP02159 1.15; 1.00  LDD2133 
Anaphase-promoting complex subunit 1 (ANAPC1) LDTP11756 0.66  LDD2133 
Aspartate aminotransferase, mitochondrial (GOT2) LDTP01783 0.91  LDD2133 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 0.57  LDD2133 
ATP synthase subunit epsilon-like protein, mitochondrial (ATP5F1EP2) LDTP17268 0.92  LDD2133 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 0.67; 0.71; 0.59  LDD2133 
ATP-citrate synthase (ACLY) LDTP04561 0.73; 0.82  LDD2133 
ATP-dependent RNA helicase A (DHX9) LDTP05550 0.56; 0.58; 0.56  LDD2133 
ATP-dependent RNA helicase DDX24 (DDX24) LDTP15942 0.82  LDD2133 
ATP-dependent RNA helicase DDX39A (DDX39A) LDTP00192 0.75; 0.67; 0.36  LDD2133 
ATP-dependent RNA helicase DDX3Y (DDX3Y) LDTP00664 0.59; 0.67  LDD2133 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 0.51  LDD2133 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 0.63  LDD2133 
Beta-1,4-galactosyltransferase 1 (B4GALT1) LDTP02777 1.25  LDD2133 
Beta-enolase (ENO3) LDTP02700 1.27  LDD2133 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 0.58  LDD2133 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 0.49; 0.86; 0.66 ...  LDD2133 
Branched-chain-amino-acid aminotransferase, cytosolic (BCAT1) LDTP04622 0.44  LDD2133 
Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT2) LDTP00624 0.68  LDD2133 
Calpain-2 catalytic subunit (CAPN2) LDTP02911 0.49; 0.85; 0.47  LDD2133 
Calpain-9 (CAPN9) LDTP00447 0.84  LDD2133 
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (CMTR1) LDTP08773 0.45  LDD2133 
Carbonyl reductase [NADPH] 1 (CBR1) LDTP02831 0.56  LDD2133 
Carboxypeptidase D (CPD) LDTP01372 0.43  LDD2133 
Casein kinase II subunit beta (CSNK2B) LDTP05067 0.72  LDD2133 
Caspase-8 (CASP8) LDTP06211 0.53  LDD2133 
Catalase (CAT) LDTP02001 0.59; 0.57  LDD2133 
Choline-phosphate cytidylyltransferase A (PCYT1A) LDTP04261 0.70  LDD2133 
Chromosome-associated kinesin KIF4A (KIF4A) LDTP01539 0.64  LDD2133 
Citrate synthase, mitochondrial (CS) LDTP01205 0.79  LDD2133 
COP9 signalosome complex subunit 5 (COPS5) LDTP09925 0.48  LDD2133 
CTP synthase 1 (CTPS1) LDTP02922 0.72; 0.55  LDD2133 
Cullin-1 (CUL1) LDTP05946 0.46  LDD2133 
Cullin-2 (CUL2) LDTP05947 0.40  LDD2133 
Cullin-3 (CUL3) LDTP05948 0.98  LDD2133 
Cullin-4A (CUL4A) LDTP05949 0.78; 0.54  LDD2133 
Cullin-associated NEDD8-dissociated protein 1 (CAND1) LDTP08296 0.59; 0.45  LDD2133 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 0.65  LDD2133 
Cyclin-dependent kinase 4 (CDK4) LDTP02589 0.79  LDD2133 
Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) LDTP03610 0.39; 0.49  LDD2133 
Cytochrome b-c1 complex subunit 6, mitochondrial (UQCRH) LDTP02229 0.81; 0.75; 0.56 ...  LDD2133 
Cytoplasmic aconitate hydratase (ACO1) LDTP03110 1.44; 0.81  LDD2133 
Cytosol aminopeptidase (LAP3) LDTP03455 1.29; 0.73  LDD2133 
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 0.47  LDD2133 
D-dopachrome decarboxylase (DDT) LDTP03513 0.44  LDD2133 
Dehydrogenase/reductase SDR family member 11 (DHRS11) LDTP07678 0.66  LDD2133 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 0.38  LDD2133 
Delta(24)-sterol reductase (DHCR24) LDTP06375 0.63  LDD2133 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 0.79; 0.55  LDD2133 
Deoxycytidylate deaminase (DCTD) LDTP03643 0.55  LDD2133 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 0.39; 0.52  LDD2133 
Deoxyribose-phosphate aldolase (DERA) LDTP13941 0.73  LDD2133 
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT) LDTP03669 0.89; 0.55  LDD2133 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 0.64; 0.65  LDD2133 
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (DLAT) LDTP02497 0.72  LDD2133 
Dipeptidyl peptidase 9 (DPP9) LDTP08198 0.71  LDD2133 
Diphosphomevalonate decarboxylase (MVD) LDTP04567 0.63  LDD2133 
Disintegrin and metalloproteinase domain-containing protein 15 (ADAM15) LDTP05874 0.47  LDD2133 
DNA (cytosine-5)-methyltransferase 1 (DNMT1) LDTP03350 0.55  LDD2133 
DNA replication licensing factor MCM2 (MCM2) LDTP04286 0.71  LDD2133 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 1.10; 0.60  LDD2133 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 1.17  LDD2133 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 0.50  LDD2133 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 0.62  LDD2133 
DNA topoisomerase 1 (TOP1) LDTP02567 0.73  LDD2133 
DNA topoisomerase 2-alpha (TOP2A) LDTP02568 1.03  LDD2133 
DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 0.74; 0.55; 0.79 ...  LDD2133 
DNA-directed RNA polymerase I subunit RPA1 (POLR1A) LDTP01636 0.50  LDD2133 
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (POLR2H) LDTP04507 0.41  LDD2133 
Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) LDTP13087 0.90  LDD2133 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 0.94  LDD2133 
Double-stranded RNA-specific adenosine deaminase (ADAR) LDTP04690 0.57  LDD2133 
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) LDTP04103 0.79  LDD2133 
Dynamin-1-like protein (DNM1L) LDTP00273 0.53  LDD2133 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 0.60  LDD2133 
E3 SUMO-protein ligase RanBP2 (RANBP2) LDTP04310 0.68; 0.72; 0.93  LDD2133 
E3 ubiquitin-protein ligase HUWE1 (HUWE1) LDTP08135 0.55; 0.40  LDD2133 
E3 ubiquitin-protein ligase RBX1 (RBX1) LDTP05019 0.79  LDD2133 
E3 ubiquitin-protein ligase SH3RF2 (SH3RF2) LDTP09493 0.95  LDD2133 
E3 ubiquitin-protein ligase SMURF2 (SMURF2) LDTP12138 0.92  LDD2133 
E3 ubiquitin-protein ligase TRIM33 (TRIM33) LDTP13702 0.58  LDD2133 
E3 ubiquitin-protein ligase UBR4 (UBR4) LDTP07118 0.41  LDD2133 
E3 ubiquitin/ISG15 ligase TRIM25 (TRIM25) LDTP06098 0.69  LDD2133 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 0.58  LDD2133 
Elongation factor 2 (EEF2) LDTP02672 0.51; 0.91; 0.79 ...  LDD2133 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 0.74  LDD2133 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 0.77  LDD2133 
Epidermal growth factor receptor (EGFR) LDTP01785 1.20  LDD2133 
ERO1-like protein alpha (ERO1A) LDTP10386 0.77  LDD2133 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 0.80  LDD2133 
Eukaryotic translation initiation factor 2 subunit 3B (EIF2S3B) LDTP14895 0.39  LDD2133 
Eukaryotic translation initiation factor 3 subunit F (EIF3F) LDTP00246 0.58  LDD2133 
Eukaryotic translation initiation factor 5B (EIF5B) LDTP01063 0.73; 0.70  LDD2133 
Exosome complex component 10 (EXOSC10) LDTP05312 0.64  LDD2133 
Exosome complex component MTR3 (EXOSC6) LDTP07054 0.62; 3.06  LDD2133 
Exosome complex component RRP42 (EXOSC7) LDTP06283 0.53  LDD2133 
Exosome complex component RRP43 (EXOSC8) LDTP10110 0.75; 0.76  LDD2133 
Exosome RNA helicase MTR4 (MTREX) LDTP03975 0.47; 0.42  LDD2133 
FACT complex subunit SPT16 (SUPT16H) LDTP14109 0.88  LDD2133 
FAST kinase domain-containing protein 2, mitochondrial (FASTKD2) LDTP12862 0.85  LDD2133 
Fatty acid synthase (FASN) LDTP04243 0.68; 0.72; 0.52 ...  LDD2133 
Fumarylacetoacetase (FAH) LDTP02868 0.61  LDD2133 
Galactokinase (GALK1) LDTP04424 0.54  LDD2133 
Gamma-glutamylcyclotransferase (GGCT) LDTP01164 0.55  LDD2133 
GDP-fucose protein O-fucosyltransferase 1 (POFUT1) LDTP11905 0.59  LDD2133 
Glucosamine 6-phosphate N-acetyltransferase (GNPNAT1) LDTP10264 0.64  LDD2133 
Glucoside xylosyltransferase 1 (GXYLT1) LDTP14932 0.65  LDD2133 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (GFPT2) LDTP01423 0.58  LDD2133 
Glutaredoxin-1 (GLRX) LDTP03786 1.04  LDD2133 
Glutaryl-CoA dehydrogenase, mitochondrial (GCDH) LDTP09939 0.58  LDD2133 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 0.53  LDD2133 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 0.41; 0.81  LDD2133 
Glutathione synthetase (GSS) LDTP04200 0.59  LDD2133 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 0.47; 0.48; 0.85  LDD2133 
Glycerol-3-phosphate phosphatase (PGP) LDTP00089 1.39  LDD2133 
Glycine--tRNA ligase (GARS1) LDTP03946 0.98  LDD2133 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 0.71  LDD2133 
Glycylpeptide N-tetradecanoyltransferase 1 (NMT1) LDTP03537 0.68  LDD2133 
Glycylpeptide N-tetradecanoyltransferase 2 (NMT2) LDTP01001 0.67  LDD2133 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 1.05  LDD2133 
GMP reductase 2 (GMPR2) LDTP13080 5.97; 0.52; 0.53  LDD2133 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 0.75  LDD2133 
GTP-binding nuclear protein Ran (RAN) LDTP05007 0.59; 0.57  LDD2133 
Guanine nucleotide-binding protein-like 3 (GNL3) LDTP11297 0.60  LDD2133 
H/ACA ribonucleoprotein complex subunit DKC1 (DKC1) LDTP01061 0.54  LDD2133 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 0.57; 0.50  LDD2133 
Heme oxygenase 2 (HMOX2) LDTP03540 0.40; 1.03  LDD2133 
Hexokinase-1 (HK1) LDTP02991 0.68; 0.67  LDD2133 
Hexokinase-2 (HK2) LDTP04531 0.56; 0.50  LDD2133 
Histidine--tRNA ligase, cytoplasmic (HARS1) LDTP02602 0.69  LDD2133 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 0.89  LDD2133 
Histone deacetylase 1 (HDAC1) LDTP05918 0.70  LDD2133 
Histone-lysine N-methyltransferase SETD7 (SETD7) LDTP09543 0.58  LDD2133 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 0.60  LDD2133 
Hydroxysteroid dehydrogenase-like protein 2 (HSDL2) LDTP07762 0.61; 0.62  LDD2133 
Inorganic pyrophosphatase 2, mitochondrial (PPA2) LDTP11842 0.53  LDD2133 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 0.61  LDD2133 
Inositol monophosphatase 1 (IMPA1) LDTP03470 0.58  LDD2133 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 0.49  LDD2133 
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A) LDTP04345 0.59; 0.33  LDD2133 
Isopentenyl-diphosphate Delta-isomerase 1 (IDI1) LDTP06006 0.55  LDD2133 
Ketohexokinase (KHK) LDTP04340 0.55  LDD2133 
Ketosamine-3-kinase (FN3KRP) LDTP16025 0.92  LDD2133 
Kinesin-like protein KIF2A (KIF2A) LDTP00188 1.09  LDD2133 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 0.55  LDD2133 
Large ribosomal subunit protein mL44 (MRPL44) LDTP12098 0.77  LDD2133 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 0.57; 0.46; 0.43  LDD2133 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 0.76; 0.41  LDD2133 
Lysine--tRNA ligase (KARS1) LDTP06294 0.67  LDD2133 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 0.49  LDD2133 
Macrophage migration inhibitory factor (MIF) LDTP02713 0.60  LDD2133 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 0.88; 0.67; 0.57  LDD2133 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 0.44; 0.51; 0.49 ...  LDD2133 
Matrix metalloproteinase-14 (MMP14) LDTP04352 0.67  LDD2133 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 0.54  LDD2133 
Microsomal glutathione S-transferase 1 (MGST1) LDTP02506 0.61  LDD2133 
Mitochondrial Rho GTPase 2 (RHOT2) LDTP08596 0.56  LDD2133 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 0.66  LDD2133 
Molybdopterin synthase catalytic subunit (MOCS2) LDTP01747 0.72  LDD2133 
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) LDTP07651 0.74; 0.76  LDD2133 
mRNA cap guanine-N7 methyltransferase (RNMT) LDTP00686 0.54  LDD2133 
Multifunctional protein CAD (CAD) LDTP03401 0.71; 0.63; 0.85 ...  LDD2133 
MYG1 exonuclease (MYG1) LDTP12154 0.51  LDD2133 
Myosin-9 (MYH9) LDTP03764 0.68; 0.53; 0.85 ...  LDD2133 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 0.55; 0.92  LDD2133 
N-alpha-acetyltransferase 16, NatA auxiliary subunit (NAA16) LDTP07455 0.85  LDD2133 
NADH dehydrogenase 1 alpha subcomplex subunit 2 (NDUFA2) LDTP00833 1.89  LDD2133 
NADH dehydrogenase 1 alpha subcomplex subunit 8 (NDUFA8) LDTP04494 0.58  LDD2133 
NADH dehydrogenase flavoprotein 1, mitochondrial (NDUFV1) LDTP04317 0.66  LDD2133 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 0.69  LDD2133 
Neurolysin, mitochondrial (NLN) LDTP11494 0.57; 0.62  LDD2133 
Neutral alpha-glucosidase AB (GANAB) LDTP06192 0.64; 0.58  LDD2133 
Nicotinate-nucleotide pyrophosphorylase [carboxylating] (QPRT) LDTP06346 0.49  LDD2133 
Nuclear pore complex protein Nup98-Nup96 (NUP98) LDTP04547 0.60  LDD2133 
Nucleolar RNA helicase 2 (DDX21) LDTP12469 0.95  LDD2133 
Omega-amidase NIT2 (NIT2) LDTP12428 0.50  LDD2133 
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (CPOX) LDTP03813 0.58; 0.47  LDD2133 
Parkinson disease protein 7 (PARK7) LDTP10878 0.47; 0.55  LDD2133 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 0.69; 0.61; 0.69  LDD2133 
Peptidyl-prolyl cis-trans isomerase B (PPIB) LDTP03216 0.38  LDD2133 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 0.57  LDD2133 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 0.55; 0.61  LDD2133 
Peptidyl-prolyl cis-trans isomerase-like 1 (PPIL1) LDTP13976 0.60  LDD2133 
Peptidyl-tRNA hydrolase 2, mitochondrial (PTRH2) LDTP13989 0.95  LDD2133 
Peroxiredoxin-1 (PRDX1) LDTP05503 0.58  LDD2133 
Peroxisomal acyl-coenzyme A oxidase 2 (ACOX2) LDTP10859 0.55  LDD2133 
Peroxisomal multifunctional enzyme type 2 (HSD17B4) LDTP04440 0.75  LDD2133 
Persulfide dioxygenase ETHE1, mitochondrial (ETHE1) LDTP01633 0.53  LDD2133 
Phenylalanine--tRNA ligase beta subunit (FARSB) LDTP12586 0.73  LDD2133 
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PIP4K2A) LDTP04177 0.65  LDD2133 
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2) LDTP06638 0.62  LDD2133 
Phosphoglucomutase-1 (PGM1) LDTP03818 0.47  LDD2133 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 0.46; 0.60; 0.50  LDD2133 
Phosphoglycerate mutase 1 (PGAM1) LDTP02963 0.71  LDD2133 
Phospholipid scramblase 1 (PLSCR1) LDTP00558 0.86  LDD2133 
Phosphopentomutase (PGM2) LDTP10326 9.11  LDD2133 
Phosphoribosylformylglycinamidine synthase (PFAS) LDTP00527 0.61; 0.66; 0.45  LDD2133 
Platelet-activating factor acetylhydrolase IB subunit alpha1 (PAFAH1B3) LDTP06315 0.93  LDD2133 
Platelet-activating factor acetylhydrolase IB subunit alpha2 (PAFAH1B2) LDTP05078 0.60  LDD2133 
Poly [ADP-ribose] polymerase 1 (PARP1) LDTP02375 0.83; 0.49  LDD2133 
Pre-mRNA-processing factor 19 (PRPF19) LDTP13623 0.65  LDD2133 
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (FTSJ3) LDTP08629 0.68  LDD2133 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 0.56  LDD2133 
Presequence protease, mitochondrial (PITRM1) LDTP07003 0.52  LDD2133 
Probable ATP-dependent RNA helicase DDX17 (DDX17) LDTP09899 0.78; 0.55  LDD2133 
Probable ATP-dependent RNA helicase DDX23 (DDX23) LDTP11248 0.55  LDD2133 
Probable ATP-dependent RNA helicase DDX46 (DDX46) LDTP07932 0.41  LDD2133 
Probable ATP-dependent RNA helicase DDX47 (DDX47) LDTP11730 0.89  LDD2133 
Probable ATP-dependent RNA helicase DDX5 (DDX5) LDTP02924 0.43; 0.56  LDD2133 
Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (ALG8) LDTP11290 0.55  LDD2133 
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X) LDTP09961 0.71  LDD2133 
Proliferation-associated protein 2G4 (PA2G4) LDTP13750 0.57; 0.81  LDD2133 
Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB) LDTP02096 0.60  LDD2133 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 0.56  LDD2133 
Prostaglandin E synthase 3 (PTGES3) LDTP06338 0.61; 1.32  LDD2133 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 0.50; 0.26  LDD2133 
Proteasome subunit alpha type-4 (PSMA4) LDTP03333 0.67  LDD2133 
Proteasome subunit alpha type-5 (PSMA5) LDTP03413 0.61  LDD2133 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 0.48; 1.60  LDD2133 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 0.50  LDD2133 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 0.54; 0.74  LDD2133 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 0.50  LDD2133 
Proteasome subunit beta type-3 (PSMB3) LDTP04284 0.51  LDD2133 
Proteasome subunit beta type-7 (PSMB7) LDTP10862 0.68  LDD2133 
Protein arginine N-methyltransferase 1 (PRMT1) LDTP10997 0.84  LDD2133 
Protein arginine N-methyltransferase 5 (PRMT5) LDTP00418 0.59  LDD2133 
Protein disulfide-isomerase (P4HB) LDTP02188 0.72; 0.43  LDD2133 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 0.93; 0.83  LDD2133 
Protein kinase C delta type (PRKCD) LDTP05461 0.85  LDD2133 
Protein phosphatase 1G (PPM1G) LDTP00616 0.61  LDD2133 
Protein regulator of cytokinesis 1 (PRC1) LDTP00828 0.93  LDD2133 
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 0.67; 0.61; 1.13 ...  LDD2133 
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT1) LDTP03152 0.49  LDD2133 
Purine nucleoside phosphorylase (PNP) LDTP01781 0.70  LDD2133 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 0.49  LDD2133 
Putative hydroxypyruvate isomerase (HYI) LDTP14998 1.47  LDD2133 
Pyruvate carboxylase, mitochondrial (PC) LDTP02576 0.60  LDD2133 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 0.65; 0.81  LDD2133 
Pyruvate kinase PKM (PKM) LDTP02733 0.78; 0.58  LDD2133 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 0.75  LDD2133 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 0.50  LDD2133 
Ras-related C3 botulinum toxin substrate 2 (RAC2) LDTP02768 0.72  LDD2133 
Ras-related GTP-binding protein B (RRAGB) LDTP07263 0.57  LDD2133 
Ras-related protein Rab-13 (RAB13) LDTP04401 0.66  LDD2133 
Ras-related protein Rab-14 (RAB14) LDTP04901 0.89  LDD2133 
Ras-related protein Rab-1A (RAB1A) LDTP05006 0.62  LDD2133 
Ras-related protein Rab-34 (RAB34) LDTP11535 0.98; 1.10; 0.87  LDD2133 
Ras-related protein Rab-7a (RAB7A) LDTP04399 0.95  LDD2133 
Ras-related protein Rab-8A (RAB8A) LDTP04888 0.57  LDD2133 
Regulator of nonsense transcripts 1 (UPF1) LDTP09921 0.60  LDD2133 
Replication factor C subunit 2 (RFC2) LDTP03726 0.69  LDD2133 
Replication factor C subunit 3 (RFC3) LDTP03911 0.70  LDD2133 
Retinol dehydrogenase 11 (RDH11) LDTP09364 0.62  LDD2133 
Rho-associated protein kinase 2 (ROCK2) LDTP01127 0.86  LDD2133 
Rho-related GTP-binding protein RhoQ (RHOQ) LDTP02885 0.68  LDD2133 
Ribonuclease H2 subunit A (RNASEH2A) LDTP01311 0.41  LDD2133 
Ribonucleoside-diphosphate reductase large subunit (RRM1) LDTP03259 0.75; 0.55  LDD2133 
Ribonucleoside-diphosphate reductase subunit M2 (RRM2) LDTP03592 0.87  LDD2133 
Ribose-5-phosphate isomerase (RPIA) LDTP04236 0.72  LDD2133 
Ribose-phosphate pyrophosphokinase 1 (PRPS1) LDTP04882 0.58  LDD2133 
Ribose-phosphate pyrophosphokinase 3 (PRPS1L1) LDTP03097 0.64  LDD2133 
Ribosomal RNA small subunit methyltransferase NEP1 (EMG1) LDTP09951 0.83  LDD2133 
Ribulose-phosphate 3-epimerase (RPE) LDTP10094 0.47  LDD2133 
RNA cytidine acetyltransferase (NAT10) LDTP11690 0.68  LDD2133 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 0.97  LDD2133 
RNA-splicing ligase RtcB homolog (RTCB) LDTP13992 0.55  LDD2133 
rRNA methyltransferase 3, mitochondrial (MRM3) LDTP12215 0.93  LDD2133 
RuvB-like 2 (RUVBL2) LDTP13787 0.55  LDD2133 
S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) LDTP00890 1.01  LDD2133 
S-adenosylmethionine synthase isoform type-2 (MAT2A) LDTP03577 0.60  LDD2133 
S-formylglutathione hydrolase (ESD) LDTP02521 0.66  LDD2133 
S-phase kinase-associated protein 1 (SKP1) LDTP05052 0.60  LDD2133 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 0.48; 1.01; 0.62 ...  LDD2133 
Serine beta-lactamase-like protein LACTB, mitochondrial (LACTB) LDTP05183 0.62  LDD2133 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 1.01; 0.42; 0.69  LDD2133 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 0.58  LDD2133 
Serine/threonine-protein kinase OSR1 (OXSR1) LDTP01664 0.73  LDD2133 
Serine/threonine-protein kinase VRK1 (VRK1) LDTP11030 0.91  LDD2133 
Serine/threonine-protein phosphatase 4 regulatory subunit 3B (PPP4R3B) LDTP07034 0.69  LDD2133 
Serine/threonine-protein phosphatase PGAM5, mitochondrial (PGAM5) LDTP10399 0.51  LDD2133 
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) LDTP04960 0.97  LDD2133 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 0.69; 0.77  LDD2133 
Signal recognition particle subunit SRP54 (SRP54) LDTP04890 0.93  LDD2133 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 0.65; 0.57; 0.77  LDD2133 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 0.71; 0.86; 0.64 ...  LDD2133 
Sorbitol dehydrogenase (SORD) LDTP05258 1.48  LDD2133 
Spermine synthase (SMS) LDTP04530 0.81  LDD2133 
Sphingosine-1-phosphate phosphatase 1 (SGPP1) LDTP11361 0.58  LDD2133 
Squalene synthase (FDFT1) LDTP03842 0.88  LDD2133 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 0.69  LDD2133 
Sterol O-acyltransferase 1 (SOAT1) LDTP03769 0.89  LDD2133 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 0.77  LDD2133 
Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA) LDTP03572 0.53; 0.64  LDD2133 
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (SUCLG1) LDTP04566 0.41  LDD2133 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 0.63; 0.49  LDD2133 
SUMO-conjugating enzyme UBC9 (UBE2I) LDTP05062 0.66  LDD2133 
Thimet oligopeptidase (THOP1) LDTP04542 0.40  LDD2133 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 0.62; 0.52; 0.60 ...  LDD2133 
Thioredoxin reductase 1, cytoplasmic (TXNRD1) LDTP06658 0.67  LDD2133 
Threonine--tRNA ligase 1, cytoplasmic (TARS1) LDTP03365 0.44  LDD2133 
Thymidine kinase, cytosolic (TK1) LDTP02022 0.55; 0.68  LDD2133 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 0.78; 0.90  LDD2133 
Transforming protein RhoA (RHOA) LDTP04927 0.63  LDD2133 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 1.00; 0.61  LDD2133 
Translin (TSN) LDTP06427 0.45  LDD2133 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 0.79  LDD2133 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 0.63; 0.80; 0.62  LDD2133 
Triokinase/FMN cyclase (TKFC) LDTP06779 0.74  LDD2133 
Triosephosphate isomerase (TPI1) LDTP04851 0.54; 0.61; 0.77  LDD2133 
Tripeptidyl-peptidase 2 (TPP2) LDTP03469 0.73; 0.51  LDD2133 
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (TRMT61A) LDTP10320 0.56; 0.44  LDD2133 
tRNA (guanine(6)-N2)-methyltransferase THUMP3 (THUMPD3) LDTP11266 0.45  LDD2133 
Tyrosine-protein phosphatase non-receptor type 1 (PTPN1) LDTP02935 0.52  LDD2133 
Tyrosine-protein phosphatase non-receptor type 23 (PTPN23) LDTP11887 0.83  LDD2133 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 0.97  LDD2133 
Ubiquitin carboxyl-terminal hydrolase 5 (USP5) LDTP04074 0.57; 0.63  LDD2133 
Ubiquitin-conjugating enzyme E2 Z (UBE2Z) LDTP12046 0.56  LDD2133 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 0.70; 0.68  LDD2133 
Ubiquitin-like modifier-activating enzyme 6 (UBA6) LDTP00013 0.76  LDD2133 
Ubiquitin-protein ligase E3A (UBE3A) LDTP05446 1.00  LDD2133 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 1.02; 0.40; 0.60  LDD2133 
UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1) LDTP12851 0.66  LDD2133 
UDP-glucuronic acid decarboxylase 1 (UXS1) LDTP09074 0.82  LDD2133 
UDP-N-acetylhexosamine pyrophosphorylase (UAP1) LDTP06517 0.57  LDD2133 
UMP-CMP kinase (CMPK1) LDTP03519 0.62  LDD2133 
Uridine 5'-monophosphate synthase (UMPS) LDTP02548 0.82  LDD2133 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 1.09  LDD2133 
Vacuolar protein sorting-associated protein 4B (VPS4B) LDTP01186 0.51  LDD2133 
Valine--tRNA ligase (VARS1) LDTP03366 0.97  LDD2133 
Very long chain fatty acid elongase 5 (ELOVL5) LDTP12841 0.60  LDD2133 
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) LDTP04289 0.55  LDD2133 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 0.80  LDD2133 
Vesicle-fusing ATPase (NSF) LDTP04096 0.61  LDD2133 
WD repeat-containing protein 82 (WDR82) LDTP07715 0.41  LDD2133 
X-ray repair cross-complementing protein 5 (XRCC5) LDTP02642 0.53; 0.71  LDD2133 
X-ray repair cross-complementing protein 6 (XRCC6) LDTP02640 0.68  LDD2133 
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⏷ Show the Full List of 374 Enzyme
104 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein gamma (YWHAG) LDTP04953 0.35  LDD2133 
14-3-3 protein theta (YWHAQ) LDTP03385 0.49; 0.47  LDD2133 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 0.44  LDD2133 
ADP-ribosylation factor-binding protein GGA1 (GGA1) LDTP13415 0.56  LDD2133 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 0.67; 0.87  LDD2133 
Annexin A6 (ANXA6) LDTP02247 0.45; 0.47  LDD2133 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 0.61  LDD2133 
AP-2 complex subunit alpha-1 (AP2A1) LDTP01673 0.62  LDD2133 
AP-2 complex subunit beta (AP2B1) LDTP05038 0.60; 0.40; 0.66  LDD2133 
ATP synthase subunit d, mitochondrial (ATP5PD) LDTP14509 0.64  LDD2133 
ATP synthase subunit gamma, mitochondrial (ATP5F1C) LDTP03810 0.73  LDD2133 
ATP-binding cassette sub-family F member 2 (ABCF2) LDTP18526 0.47  LDD2133 
Calreticulin (CALR) LDTP03402 0.46  LDD2133 
CD151 antigen (CD151) LDTP04187 1.58; 1.71; 1.47 ...  LDD2133 
CD44 antigen (CD44) LDTP02823 0.41; 0.65  LDD2133 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 0.31; 0.92  LDD2133 
Clathrin heavy chain 1 (CLTC) LDTP05252 0.63; 0.70; 0.55 ...  LDD2133 
Clathrin light chain B (CLTB) LDTP02353 0.80  LDD2133 
Copine-1 (CPNE1) LDTP10989 0.67  LDD2133 
Copine-3 (CPNE3) LDTP01133 0.70  LDD2133 
Cytochrome c oxidase subunit 5B, mitochondrial (COX5B) LDTP02504 0.72  LDD2133 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 0.64  LDD2133 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) LDTP02057 0.36  LDD2133 
Dysferlin (DYSF) LDTP01355 0.63  LDD2133 
Endoplasmic reticulum junction formation protein lunapark (LNPK) LDTP11609 0.36  LDD2133 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 0.66  LDD2133 
ER membrane protein complex subunit 8 (EMC8) LDTP00760 1.28  LDD2133 
Exportin-2 (CSE1L) LDTP04662 0.56; 0.56; 0.59 ...  LDD2133 
Exportin-5 (XPO5) LDTP12142 0.66  LDD2133 
Fatty acid-binding protein 5 (FABP5) LDTP05292 0.67; 0.75; 0.65 ...  LDD2133 
Filamin-A (FLNA) LDTP03107 0.88; 0.53; 0.96 ...  LDD2133 
Filamin-B (FLNB) LDTP01197 0.49; 0.67; 0.76 ...  LDD2133 
Filamin-C (FLNC) LDTP06103 0.59; 0.91; 0.61 ...  LDD2133 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1) LDTP05017 0.84  LDD2133 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2) LDTP05020 0.89; 0.59; 0.55  LDD2133 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 0.36  LDD2133 
Importin subunit alpha-7 (KPNA6) LDTP01031 0.60; 0.55  LDD2133 
Importin subunit beta-1 (KPNB1) LDTP06242 0.56  LDD2133 
Importin-11 (IPO11) LDTP13322 0.98  LDD2133 
Importin-4 (IPO4) LDTP09515 0.93; 0.56; 0.61 ...  LDD2133 
Importin-5 (IPO5) LDTP00266 0.50; 0.54; 0.58 ...  LDD2133 
Importin-7 (IPO7) LDTP01574 0.65; 0.47  LDD2133 
Importin-9 (IPO9) LDTP10663 0.59  LDD2133 
Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) LDTP06153 0.67  LDD2133 
Integrin alpha-6 (ITGA6) LDTP03211 0.94  LDD2133 
Integrin beta-1 (ITGB1) LDTP02122 0.57  LDD2133 
LETM1 domain-containing protein LETM2, mitochondrial (LETM2) LDTP14898 0.66  LDD2133 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 0.68; 0.43; 0.77  LDD2133 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 0.68  LDD2133 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 0.82  LDD2133 
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1) LDTP13698 0.55  LDD2133 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 0.65  LDD2133 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 0.68; 0.57  LDD2133 
mRNA export factor GLE1 (GLE1) LDTP06902 0.44  LDD2133 
Myeloid-associated differentiation marker (MYADM) LDTP10806 0.92  LDD2133 
Myoferlin (MYOF) LDTP12916 0.52; 0.63; 0.54 ...  LDD2133 
Nuclear cap-binding protein subunit 1 (NCBP1) LDTP05591 0.54  LDD2133 
Nuclear pore complex protein Nup153 (NUP153) LDTP04309 0.84  LDD2133 
Nuclear pore complex protein Nup205 (NUP205) LDTP09825 0.91  LDD2133 
Nuclear pore complex protein Nup50 (NUP50) LDTP13498 0.91; 0.94  LDD2133 
Nuclear pore complex protein Nup85 (NUP85) LDTP11310 0.58  LDD2133 
Nucleoporin NDC1 (NDC1) LDTP11213 0.98  LDD2133 
Nucleoprotein TPR (TPR) LDTP02612 0.37; 0.51  LDD2133 
Podocalyxin (PODXL) LDTP00321 1.02  LDD2133 
Prohibitin 1 (PHB1) LDTP03717 0.62  LDD2133 
Prosaposin (PSAP) LDTP02215 1.15  LDD2133 
Protein S100-A10 (S100A10) LDTP04885 0.49  LDD2133 
Protein SEC13 homolog (SEC13) LDTP04707 0.90; 1.62  LDD2133 
Protein SON (SON) LDTP02959 0.86  LDD2133 
Protein transport protein Sec31A (SEC31A) LDTP01478 0.82  LDD2133 
Protein transport protein Sec61 subunit gamma (SEC61G) LDTP04850 0.27  LDD2133 
Ran GTPase-activating protein 1 (RANGAP1) LDTP04082 0.57; 0.51  LDD2133 
Serine/arginine repetitive matrix protein 1 (SRRM1) LDTP08637 0.55  LDD2133 
Signal recognition particle 9 kDa protein (SRP9) LDTP04259 0.60  LDD2133 
Signal recognition particle subunit SRP68 (SRP68) LDTP13262 0.60  LDD2133 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 0.49  LDD2133 
Sodium-coupled neutral amino acid symporter 1 (SLC38A1) LDTP11824 1.03  LDD2133 
Sodium/myo-inositol cotransporter (SLC5A3) LDTP04585 0.75  LDD2133 
Sodium/potassium-transporting ATPase subunit beta-1 (ATP1B1) LDTP02068 0.77; 0.84  LDD2133 
Sodium/potassium-transporting ATPase subunit beta-3 (ATP1B3) LDTP04624 0.55  LDD2133 
Solute carrier family 25 member 3 (SLC25A3) LDTP05238 0.69  LDD2133 
Sortilin (SORT1) LDTP10885 1.00  LDD2133 
Spectrin beta chain, non-erythrocytic 1 (SPTBN1) LDTP05273 0.84  LDD2133 
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (SDHC) LDTP10931 0.79  LDD2133 
T-complex protein 1 subunit delta (CCT4) LDTP04391 0.69; 0.62; 0.51 ...  LDD2133 
Talin-1 (TLN1) LDTP14031 0.82; 0.60; 0.62 ...  LDD2133 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 0.70; 0.64  LDD2133 
Tissue factor (F3) LDTP02686 0.63  LDD2133 
TP53-regulated inhibitor of apoptosis 1 (TRIAP1) LDTP00847 0.49  LDD2133 
Transferrin receptor protein 1 (TFRC) LDTP01969 0.87  LDD2133 
Translocation protein SEC62 (SEC62) LDTP15838 0.68; 0.61  LDD2133 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 0.49; 0.34  LDD2133 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 0.77  LDD2133 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 0.71  LDD2133 
Transmembrane protein 214 (TMEM214) LDTP07477 1.12  LDD2133 
Tricarboxylate transport protein, mitochondrial (SLC25A1) LDTP04553 0.66  LDD2133 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 0.96; 0.72; 0.75  LDD2133 
Vesicle-associated membrane protein-associated protein A (VAPA) LDTP12966 0.56; 0.50  LDD2133 
Vesicle-associated membrane protein-associated protein B/C (VAPB) LDTP01556 0.30  LDD2133 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 0.53; 0.50  LDD2133 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 0.68  LDD2133 
Zinc transporter ZIP10 (SLC39A10) LDTP13543 0.76  LDD2133 
Zinc transporter ZIP13 (SLC39A13) LDTP10375 0.92  LDD2133 
Zinc transporter ZIP6 (SLC39A6) LDTP05869 0.70  LDD2133 
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⏷ Show the Full List of 104 Transporter and channel
14 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
CCAAT/enhancer-binding protein beta (CEBPB) LDTP02914 0.70  LDD2133 
Chorion-specific transcription factor GCMb (GCM2) LDTP01270 0.58  LDD2133 
Core-binding factor subunit beta (CBFB) LDTP06012 0.56  LDD2133 
Dr1-associated corepressor (DRAP1) LDTP06229 0.66  LDD2133 
eIF5-mimic protein 1 (BZW2) LDTP14241 0.90  LDD2133 
Forkhead box protein K1 (FOXK1) LDTP05201 0.50  LDD2133 
Fos-related antigen 1 (FOSL1) LDTP02786 0.55  LDD2133 
Gamma-interferon-inducible protein 16 (IFI16) LDTP06602 0.90  LDD2133 
General transcription factor II-I (GTF2I) LDTP05101 0.53  LDD2133 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 0.60; 0.57  LDD2133 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 0.77  LDD2133 
Nuclear autoantigen Sp-100 (SP100) LDTP03237 0.57  LDD2133 
Nuclear factor of activated T-cells, cytoplasmic 4 (NFATC4) LDTP06231 0.28  LDD2133 
Transcriptional activator protein Pur-alpha (PURA) LDTP05248 0.89  LDD2133 
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⏷ Show the Full List of 14 Transcription factor
4 Immunoglobulin Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
CD166 antigen (ALCAM) LDTP05973 0.88  LDD2133 
Cell surface glycoprotein MUC18 (MCAM) LDTP04020 0.95  LDD2133 
Inactive tyrosine-protein kinase 7 (PTK7) LDTP05819 0.82  LDD2133 
Intercellular adhesion molecule 1 (ICAM1) LDTP02106 0.69  LDD2133 
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3 Cytokine and receptor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Endoglin (ENG) LDTP02923 0.83; 0.77  LDD2133 
Interleukin-6 receptor subunit beta (IL6ST) LDTP03881 0.94  LDD2133 
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) LDTP00220 1.05; 0.96  LDD2133 
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392 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 1.83  LDD2133 
26S proteasome non-ATPase regulatory subunit 6 (PSMD6) LDTP06273 0.60  LDD2133 
60S ribosome subunit biogenesis protein NIP7 homolog (NIP7) LDTP13779 0.85; 0.46  LDD2133 
Abnormal spindle-like microcephaly-associated protein (ASPM) LDTP08716 0.57  LDD2133 
Acidic fibroblast growth factor intracellular-binding protein (FIBP) LDTP00765 0.89  LDD2133 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 0.55  LDD2133 
Actin-like protein 6A (ACTL6A) LDTP01756 0.44  LDD2133 
Actin-related protein 2 (ACTR2) LDTP04903 0.63  LDD2133 
Actin-related protein 2/3 complex subunit 1A (ARPC1A) LDTP15664 0.62  LDD2133 
Actin-related protein 2/3 complex subunit 1B (ARPC1B) LDTP00550 0.66  LDD2133 
Actin-related protein 2/3 complex subunit 3 (ARPC3) LDTP00552 0.86  LDD2133 
Actin-related protein 3 (ACTR3) LDTP04902 0.71  LDD2133 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 0.71; 0.42; 0.53 ...  LDD2133 
ADP-ribosylation factor GTPase-activating protein 2 (ARFGAP2) LDTP08935 1.02  LDD2133 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 0.46  LDD2133 
Alpha-parvin (PARVA) LDTP12671 0.50  LDD2133 
Alpha-soluble NSF attachment protein (NAPA) LDTP04647 0.95  LDD2133 
Anillin (ANLN) LDTP12443 0.59  LDD2133 
Ankycorbin (RAI14) LDTP12963 0.42  LDD2133 
Annexin A4 (ANXA4) LDTP02354 0.67  LDD2133 
Annexin A7 (ANXA7) LDTP03030 0.56  LDD2133 
AP-1 complex subunit mu-2 (AP1M2) LDTP14286 0.81  LDD2133 
Armadillo repeat-containing protein 6 (ARMC6) LDTP15101 0.50; 0.62  LDD2133 
Astrocytic phosphoprotein PEA-15 (PEA15) LDTP06323 0.39  LDD2133 
Ataxin-10 (ATXN10) LDTP13091 0.57  LDD2133 
BAG family molecular chaperone regulator 3 (BAG3) LDTP01684 0.77  LDD2133 
Barrier-to-autointegration factor (BANF1) LDTP01250 1.67; 0.38  LDD2133 
BolA-like protein 2 (BOLA2; BOLA2B) LDTP11870 0.63  LDD2133 
Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A) LDTP12518 0.72  LDD2133 
BUB3-interacting and GLEBS motif-containing protein ZNF207 (ZNF207) LDTP00830 0.91  LDD2133 
Calmegin (CLGN) LDTP00493 0.60  LDD2133 
Calpastatin (CAST) LDTP03079 0.80  LDD2133 
Calponin-2 (CNN2) LDTP10864 0.72; 0.63  LDD2133 
cAMP-dependent protein kinase type I-beta regulatory subunit (PRKAR1B) LDTP03589 0.54  LDD2133 
Caprin-1 (CAPRIN1) LDTP06121 0.77  LDD2133 
Caspase activity and apoptosis inhibitor 1 (CAAP1) LDTP18416 0.77  LDD2133 
Catenin alpha-1 (CTNNA1) LDTP03711 0.51  LDD2133 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 0.77; 0.84  LDD2133 
CDK-activating kinase assembly factor MAT1 (MNAT1) LDTP04488 0.82  LDD2133 
Centromere/kinetochore protein zw10 homolog (ZW10) LDTP00720 0.63  LDD2133 
Charged multivesicular body protein 1a (CHMP1A) LDTP12285 0.40  LDD2133 
Charged multivesicular body protein 1b (CHMP1B) LDTP07984 0.21  LDD2133 
Cleavage and polyadenylation specificity factor subunit 6 (CPSF6) LDTP06584 0.66; 0.42  LDD2133 
Cleavage and polyadenylation specificity factor subunit 7 (CPSF7) LDTP08922 1.61; 0.38  LDD2133 
Cleavage stimulation factor subunit 2 (CSTF2) LDTP03665 1.00  LDD2133 
Cleavage stimulation factor subunit 2 tau variant (CSTF2T) LDTP11718 0.56  LDD2133 
Coactosin-like protein (COTL1) LDTP06024 0.63  LDD2133 
Coatomer subunit beta (COPB1) LDTP04570 0.52; 0.59; 0.78 ...  LDD2133 
Coatomer subunit beta' (COPB2) LDTP03767 0.51  LDD2133 
Coatomer subunit delta (ARCN1) LDTP04181 0.73; 0.66  LDD2133 
Cofilin-1 (CFL1) LDTP03244 0.44; 0.42; 0.25 ...  LDD2133 
Cofilin-2 (CFL2) LDTP13827 0.54  LDD2133 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 0.55; 0.51  LDD2133 
Complement decay-accelerating factor (CD55) LDTP02253 0.77  LDD2133 
Condensin complex subunit 1 (NCAPD2) LDTP06281 0.80; 0.83  LDD2133 
Condensin complex subunit 3 (NCAPG) LDTP11040 0.59  LDD2133 
Conserved oligomeric Golgi complex subunit 1 (COG1) LDTP09549 0.51  LDD2133 
Constitutive coactivator of PPAR-gamma-like protein 1 (FAM120A) LDTP12883 0.81  LDD2133 
Copper transport protein ATOX1 (ATOX1) LDTP00229 0.58; 0.80  LDD2133 
Core histone macro-H2A.1 (MACROH2A1) LDTP01195 0.47  LDD2133 
Coronin-1C (CORO1C) LDTP13580 0.53; 0.57; 0.70 ...  LDD2133 
CUGBP Elav-like family member 1 (CELF1) LDTP09913 0.47  LDD2133 
CUGBP Elav-like family member 2 (CELF2) LDTP01563 0.35  LDD2133 
Cysteine and histidine-rich domain-containing protein 1 (CHORDC1) LDTP13269 0.56; 0.43  LDD2133 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 0.74; 0.86; 0.72 ...  LDD2133 
Cytoskeleton-associated protein 5 (CKAP5) LDTP06021 0.86  LDD2133 
DAZ-associated protein 1 (DAZAP1) LDTP10271 0.57; 0.55  LDD2133 
Destrin (DSTN) LDTP04887 0.75; 0.51; 0.60 ...  LDD2133 
Disks large homolog 2 (DLG2) LDTP06448 0.62  LDD2133 
DNA damage-binding protein 1 (DDB1) LDTP06543 0.62; 0.49; 0.58  LDD2133 
DNA fragmentation factor subunit alpha (DFFA) LDTP00239 0.96; 0.73  LDD2133 
DNA mismatch repair protein Msh6 (MSH6) LDTP04518 0.52  LDD2133 
DnaJ homolog subfamily A member 1 (DNAJA1) LDTP03606 0.92  LDD2133 
DnaJ homolog subfamily A member 2 (DNAJA2) LDTP01073 0.96  LDD2133 
DnaJ homolog subfamily C member 17 (DNAJC17) LDTP18473 1.13  LDD2133 
DnaJ homolog subfamily C member 3 (DNAJC3) LDTP05789 0.81  LDD2133 
DnaJ homolog subfamily C member 7 (DNAJC7) LDTP10920 0.76  LDD2133 
Double-stranded RNA-binding protein Staufen homolog 1 (STAU1) LDTP01677 0.53  LDD2133 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 0.61  LDD2133 
Early endosome antigen 1 (EEA1) LDTP06310 0.41; 0.34  LDD2133 
Ectopic P granules protein 5 homolog (EPG5) LDTP12232 0.57  LDD2133 
ELAV-like protein 2 (ELAVL2) LDTP14824 0.75  LDD2133 
Elongin-B (ELOB) LDTP06369 0.66  LDD2133 
Embryonic polyadenylate-binding protein 2 (PABPN1L) LDTP16605 1.02  LDD2133 
Enhancer of mRNA-decapping protein 4 (EDC4) LDTP07521 0.68  LDD2133 
Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8L2) LDTP11998 0.60  LDD2133 
Epidermal growth factor receptor substrate 15-like 1 (EPS15L1) LDTP13097 0.57  LDD2133 
Eukaryotic peptide chain release factor subunit 1 (ETF1) LDTP04993 0.26  LDD2133 
Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX) LDTP04129 1.62  LDD2133 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 0.32; 0.39; 0.58  LDD2133 
Eukaryotic translation initiation factor 2A (EIF2A) LDTP11436 0.82  LDD2133 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 0.59; 0.61; 0.79  LDD2133 
Eukaryotic translation initiation factor 3 subunit B (EIF3B) LDTP04718 0.82  LDD2133 
Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 0.68  LDD2133 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 0.62  LDD2133 
Eukaryotic translation initiation factor 3 subunit J (EIF3J) LDTP01320 0.54  LDD2133 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 0.60  LDD2133 
Eukaryotic translation initiation factor 6 (EIF6) LDTP04743 0.46  LDD2133 
F-actin-capping protein subunit alpha-1 (CAPZA1) LDTP04544 0.34  LDD2133 
F-actin-capping protein subunit beta (CAPZB) LDTP04127 0.74  LDD2133 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 0.53; 0.89  LDD2133 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 0.88; 0.51  LDD2133 
Far upstream element-binding protein 3 (FUBP3) LDTP10408 0.48; 0.40  LDD2133 
Formin-like protein 1 (FMNL1) LDTP01611 0.79  LDD2133 
Galectin-1 (LGALS1) LDTP02341 0.54; 0.55; 0.46  LDD2133 
Gem-associated protein 2 (GEMIN2) LDTP00465 0.45  LDD2133 
Gem-associated protein 4 (GEMIN4) LDTP04790 0.57; 0.48  LDD2133 
General vesicular transport factor p115 (USO1) LDTP01048 0.65  LDD2133 
Gephyrin (GPHN) LDTP12448 0.67; 0.78; 0.80  LDD2133 
Glutamate-rich WD repeat-containing protein 1 (GRWD1) LDTP11058 0.48  LDD2133 
Golgi apparatus protein 1 (GLG1) LDTP09920 2.09; 0.84  LDD2133 
Growth factor receptor-bound protein 2 (GRB2) LDTP05035 0.87  LDD2133 
GrpE protein homolog 1, mitochondrial (GRPEL1) LDTP12144 0.69  LDD2133 
Guanine nucleotide-binding protein G(o) subunit alpha (GNAO1) LDTP02348 0.79  LDD2133 
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (GNAS) LDTP07022 0.91  LDD2133 
Guanine nucleotide-binding protein subunit beta-4 (GNB4) LDTP12141 1.13  LDD2133 
H/ACA ribonucleoprotein complex subunit 3 (NOP10) LDTP12350 0.49  LDD2133 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 0.48; 0.52; 0.94  LDD2133 
Heat shock protein 105 kDa (HSPH1) LDTP09811 0.70; 0.61; 0.85 ...  LDD2133 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 0.39  LDD2133 
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) LDTP00490 0.73  LDD2133 
Hepatoma-derived growth factor (HDGF) LDTP04483 0.97; 0.93  LDD2133 
Heterochromatin protein 1-binding protein 3 (HP1BP3) LDTP07068 1.01  LDD2133 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 0.30  LDD2133 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 0.78  LDD2133 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 0.41  LDD2133 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 0.39  LDD2133 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 0.61; 0.56  LDD2133 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 0.75; 0.46  LDD2133 
Heterogeneous nuclear ribonucleoprotein L (HNRNPL) LDTP02750 1.14; 0.65  LDD2133 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 0.83; 0.57; 0.64  LDD2133 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 0.65  LDD2133 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 0.84; 0.55  LDD2133 
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) LDTP11238 0.84; 0.44  LDD2133 
Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) LDTP02227 0.50  LDD2133 
Histone-binding protein RBBP4 (RBBP4) LDTP05590 0.89  LDD2133 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 0.55  LDD2133 
Host cell factor 1 (HCFC1) LDTP04434 0.62; 1.16  LDD2133 
Inner centromere protein (INCENP) LDTP12432 1.17  LDD2133 
Integrin alpha-3 (ITGA3) LDTP03342 0.98; 0.27; 0.54 ...  LDD2133 
Interleukin enhancer-binding factor 3 (ILF3) LDTP05689 0.50; 0.63  LDD2133 
Interleukin-17 receptor D (IL17RD) LDTP09211 1.10  LDD2133 
IST1 homolog (IST1) LDTP04593 0.61  LDD2133 
KH domain-containing RNA-binding protein QKI (QKI) LDTP10700 0.41  LDD2133 
Kinectin (KTN1) LDTP08238 0.36  LDD2133 
Kinesin light chain 2 (KLC2) LDTP11695 0.78  LDD2133 
La-related protein 4B (LARP4B) LDTP09820 0.79  LDD2133 
Lamin-B1 (LMNB1) LDTP03065 0.54  LDD2133 
Large ribosomal subunit protein eL14 (RPL14) LDTP04389 1.00  LDD2133 
Large ribosomal subunit protein eL15 (RPL15) LDTP04919 0.58  LDD2133 
Large ribosomal subunit protein eL18 (RPL18) LDTP05509 0.60  LDD2133 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 0.73  LDD2133 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 1.02  LDD2133 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 0.78  LDD2133 
Large ribosomal subunit protein eL30 (RPL30) LDTP05021 0.57; 0.59  LDD2133 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 0.81  LDD2133 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 1.08; 0.74; 0.81  LDD2133 
Large ribosomal subunit protein eL37 (RPL37) LDTP04943 0.75  LDD2133 
Large ribosomal subunit protein eL42 (RPL36A) LDTP05188 0.57  LDD2133 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 0.27  LDD2133 
Large ribosomal subunit protein mL38 (MRPL38) LDTP10232 1.00; 0.73  LDD2133 
Large ribosomal subunit protein mL50 (MRPL50) LDTP15429 1.09  LDD2133 
Large ribosomal subunit protein uL1 (RPL10A) LDTP05024 0.44; 0.34  LDD2133 
Large ribosomal subunit protein uL10 (RPLP0) LDTP02109 0.60  LDD2133 
Large ribosomal subunit protein uL11 (RPL12) LDTP03517 0.53  LDD2133 
Large ribosomal subunit protein uL11m (MRPL11) LDTP13971 0.50  LDD2133 
Large ribosomal subunit protein uL15 (RPL27A) LDTP04105 0.74  LDD2133 
Large ribosomal subunit protein uL18m (MRPL18) LDTP11734 0.85  LDD2133 
Large ribosomal subunit protein uL22m (MRPL22) LDTP12736 0.66  LDD2133 
Large ribosomal subunit protein uL3 (RPL3) LDTP03865 0.35; 0.77; 0.77  LDD2133 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 0.81  LDD2133 
Large ribosomal subunit protein uL5 (RPL11) LDTP05026 0.76; 0.62  LDD2133 
Large ribosomal subunit protein uL6 (RPL9; RPL9P7; RPL9P8; RPL9P9) LDTP03658 0.64; 0.72  LDD2133 
LEM domain-containing protein 2 (LEMD2) LDTP09082 0.71  LDD2133 
Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) LDTP03997 0.56; 0.65; 0.53 ...  LDD2133 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 1.01; 0.89; 0.52 ...  LDD2133 
Malignant T-cell-amplified sequence 1 (MCTS1) LDTP13532 0.78; 0.62  LDD2133 
Matrin-3 (MATR3) LDTP04027 0.92; 0.46  LDD2133 
Mediator of RNA polymerase II transcription subunit 24 (MED24) LDTP01225 1.02  LDD2133 
Mediator of RNA polymerase II transcription subunit 30 (MED30) LDTP10396 0.70  LDD2133 
Meiosis regulator and mRNA stability factor 1 (MARF1) LDTP14053 0.45  LDD2133 
Metallothionein-1X (MT1X) LDTP05159 0.87; 0.80  LDD2133 
Metallothionein-2 (MT2A) LDTP01975 0.78; 0.67  LDD2133 
Methylosome protein WDR77 (WDR77) LDTP11066 0.56  LDD2133 
MICOS complex subunit MIC19 (CHCHD3) LDTP12764 0.46; 0.84  LDD2133 
Microtubule-associated protein 4 (MAP4) LDTP03404 0.47; 0.65  LDD2133 
Midasin (MDN1) LDTP12619 0.35  LDD2133 
Mitochondrial antiviral-signaling protein (MAVS) LDTP08058 0.68  LDD2133 
Mitochondrial import receptor subunit TOM34 (TOMM34) LDTP06473 0.97  LDD2133 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 0.79; 0.70  LDD2133 
MOB-like protein phocein (MOB4) LDTP13964 0.57  LDD2133 
mRNA turnover protein 4 homolog (MRTO4) LDTP16220 0.41  LDD2133 
Myb-binding protein 1A (MYBBP1A) LDTP11079 0.57; 0.45; 0.39  LDD2133 
Myosin light polypeptide 6 (MYL6) LDTP04875 0.61  LDD2133 
Neuroblast differentiation-associated protein AHNAK (AHNAK) LDTP05597 1.28; 0.57; 0.65  LDD2133 
NF-kappa-B essential modulator (IKBKG) LDTP14268 1.00  LDD2133 
NHP2-like protein 1 (SNU13) LDTP04708 0.55; 0.54  LDD2133 
NTF2-related export protein 1 (NXT1) LDTP13461 0.34  LDD2133 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 1.13  LDD2133 
Nuclear mitotic apparatus protein 1 (NUMA1) LDTP06244 0.34; 0.75  LDD2133 
Nuclear receptor 2C2-associated protein (NR2C2AP) LDTP08338 0.67  LDD2133 
Nucleolar complex protein 2 homolog (NOC2L) LDTP14011 0.97  LDD2133 
Nucleolar complex protein 4 homolog (NOC4L) LDTP11287 0.73  LDD2133 
Nucleolar protein 16 (NOP16) LDTP16278 0.49  LDD2133 
Nucleolar protein 56 (NOP56) LDTP00313 0.85; 0.84  LDD2133 
Nucleolar protein 6 (NOL6) LDTP11993 0.42  LDD2133 
Nucleophosmin (NPM1) LDTP02164 0.47  LDD2133 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 0.67  LDD2133 
OCIA domain-containing protein 2 (OCIAD2) LDTP17157 1.05; 0.94  LDD2133 
Opioid growth factor receptor (OGFR) LDTP16155 1.02  LDD2133 
Origin recognition complex subunit 3 (ORC3) LDTP13104 1.13  LDD2133 
Oxysterol-binding protein-related protein 11 (OSBPL11) LDTP11367 0.87  LDD2133 
Paxillin (PXN) LDTP04226 0.47  LDD2133 
PDZ and LIM domain protein 7 (PDLIM7) LDTP12461 0.81  LDD2133 
Perilipin-3 (PLIN3) LDTP01021 0.42  LDD2133 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 0.55  LDD2133 
Plastin-2 (LCP1) LDTP02691 0.54; 0.34; 0.61 ...  LDD2133 
Plectin (PLEC) LDTP06330 0.61; 0.38; 0.79 ...  LDD2133 
Pleiotrophin (PTN) LDTP03102 0.53  LDD2133 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 0.57; 0.59  LDD2133 
Poly(rC)-binding protein 3 (PCBP3) LDTP04793 0.74; 0.61  LDD2133 
Polyadenylate-binding protein 1 (PABPC1) LDTP02595 0.27  LDD2133 
Polyadenylate-binding protein 4 (PABPC4) LDTP05821 0.32  LDD2133 
Pre-mRNA-processing factor 6 (PRPF6) LDTP01456 1.05  LDD2133 
Pre-mRNA-processing-splicing factor 8 (PRPF8) LDTP07526 0.54  LDD2133 
Pre-mRNA-splicing factor 38B (PRPF38B) LDTP17266 0.79  LDD2133 
Prefoldin subunit 5 (PFDN5) LDTP10873 0.57  LDD2133 
Prelamin-A/C (LMNA) LDTP01932 0.80; 0.88  LDD2133 
Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 0.80  LDD2133 
Proliferating cell nuclear antigen (PCNA) LDTP02596 0.62; 0.39  LDD2133 
Proliferation marker protein Ki-67 (MKI67) LDTP04078 1.42  LDD2133 
Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) LDTP08707 0.83  LDD2133 
Proteasomal ubiquitin receptor ADRM1 (ADRM1) LDTP06514 0.64  LDD2133 
Proteasome activator complex subunit 1 (PSME1) LDTP05484 0.79; 0.51  LDD2133 
Proteasome activator complex subunit 3 (PSME3) LDTP04917 0.62; 0.48  LDD2133 
Proteasome assembly chaperone 1 (PSMG1) LDTP01608 0.74  LDD2133 
Proteasome assembly chaperone 2 (PSMG2) LDTP10035 0.79  LDD2133 
Protein CIP2A (CIP2A) LDTP09383 0.55  LDD2133 
Protein diaphanous homolog 3 (DIAPH3) LDTP12596 0.90  LDD2133 
Protein FAM136A (FAM136A) LDTP18132 0.99; 0.63  LDD2133 
Protein FAM3C (FAM3C) LDTP09773 0.99  LDD2133 
Protein FAM98A (FAM98A) LDTP09086 0.78  LDD2133 
Protein FAM98B (FAM98B) LDTP06879 0.47  LDD2133 
Protein LSM12 (LSM12) LDTP06780 0.50  LDD2133 
Protein LTV1 homolog (LTV1) LDTP15727 0.68  LDD2133 
Protein MEMO1 (MEMO1) LDTP13942 0.57  LDD2133 
Protein Niban 1 (NIBAN1) LDTP11559 0.58  LDD2133 
Protein Niban 2 (NIBAN2) LDTP10847 0.95; 0.38; 0.84 ...  LDD2133 
Protein PRRC2C (PRRC2C) LDTP14085 0.57  LDD2133 
Protein RCC2 (RCC2) LDTP13020 0.81  LDD2133 
Protein THEM6 (THEM6) LDTP19831 0.45; 0.74; 0.80  LDD2133 
Protein transport protein Sec23A (SEC23A) LDTP06390 0.37  LDD2133 
Protein transport protein Sec23B (SEC23B) LDTP06391 0.54  LDD2133 
Protein transport protein Sec24C (SEC24C) LDTP04594 0.39  LDD2133 
Protein transport protein Sec24D (SEC24D) LDTP01440 0.74  LDD2133 
Protein unc-13 homolog D (UNC13D) LDTP07888 0.97  LDD2133 
Protein unc-45 homolog A (UNC45A) LDTP11890 0.57  LDD2133 
Putative ribosomal protein eL43-like (RPL37AP8) LDTP18837 0.69; 0.88  LDD2133 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 0.67; 0.63  LDD2133 
Rab GDP dissociation inhibitor alpha (GDI1) LDTP03574 0.51  LDD2133 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 0.47  LDD2133 
Rab proteins geranylgeranyltransferase component A 2 (CHML) LDTP03355 0.79  LDD2133 
RAD51-associated protein 1 (RAD51AP1) LDTP10105 0.82  LDD2133 
Raftlin (RFTN1) LDTP06193 0.64; 0.65  LDD2133 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 0.95  LDD2133 
Rap1 GTPase-GDP dissociation stimulator 1 (RAP1GDS1) LDTP04504 1.06  LDD2133 
Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) LDTP07878 0.56  LDD2133 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 0.84  LDD2133 
Replication protein A 14 kDa subunit (RPA3) LDTP03723 1.09  LDD2133 
Replication protein A 32 kDa subunit (RPA2) LDTP02816 0.55  LDD2133 
Replication termination factor 2 (RTF2) LDTP11434 0.84  LDD2133 
Reticulon-4 (RTN4) LDTP12412 0.72  LDD2133 
Retinoblastoma-associated protein (RB1) LDTP02146 0.65; 0.50  LDD2133 
Ribonuclease inhibitor (RNH1) LDTP02656 0.59; 0.84; 1.17  LDD2133 
Ribonucleoprotein PTB-binding 1 (RAVER1) LDTP15356 0.75  LDD2133 
Ribosomal protein eL42-like (RPL36AL) LDTP15677 0.50; 0.66  LDD2133 
Ribosomal protein eS27-like (RPS27L) LDTP07909 0.65  LDD2133 
Ribosomal protein uL16-like (RPL10L) LDTP10525 0.63  LDD2133 
Ribosome biogenesis protein BOP1 (BOP1) LDTP06046 1.19  LDD2133 
Ribosome biogenesis protein BRX1 homolog (BRIX1) LDTP15609 0.63; 0.68  LDD2133 
Ribosome maturation protein SBDS (SBDS) LDTP13966 0.46  LDD2133 
Ribosome-binding protein 1 (RRBP1) LDTP13044 0.34; 0.28; 0.60 ...  LDD2133 
RNA-binding motif, single-stranded-interacting protein 1 (RBMS1) LDTP03495 0.59  LDD2133 
RNA-binding protein EWS (EWSR1) LDTP05318 0.57; 0.46; 0.46  LDD2133 
RNA-binding protein FUS (FUS) LDTP03775 0.43; 0.43  LDD2133 
RNA-binding protein FXR1 (FXR1) LDTP04395 0.50  LDD2133 
RNA-binding protein Raly (RALY) LDTP13467 0.62  LDD2133 
RNA-binding protein RO60 (RO60) LDTP02480 0.47  LDD2133 
RRP12-like protein (RRP12) LDTP14980 0.76  LDD2133 
SAP domain-containing ribonucleoprotein (SARNP) LDTP05179 0.62  LDD2133 
Scaffold attachment factor B2 (SAFB2) LDTP06054 1.58  LDD2133 
Sequestosome-1 (SQSTM1) LDTP05898 0.71; 0.66  LDD2133 
Serine incorporator 1 (SERINC1) LDTP12544 0.46  LDD2133 
Serine-threonine kinase receptor-associated protein (STRAP) LDTP13991 1.05  LDD2133 
Serine/arginine repetitive matrix protein 2 (SRRM2) LDTP13746 0.75; 0.59  LDD2133 
Serine/arginine-rich splicing factor 1 (SRSF1) LDTP05539 0.46  LDD2133 
Serine/arginine-rich splicing factor 3 (SRSF3) LDTP05197 1.29; 1.03  LDD2133 
Serine/arginine-rich splicing factor 7 (SRSF7) LDTP06583 0.62  LDD2133 
Serine/threonine-protein phosphatase 6 regulatory subunit 1 (PPP6R1) LDTP13701 0.48  LDD2133 
Serine/threonine-protein phosphatase 6 regulatory subunit 3 (PPP6R3) LDTP06983 0.56  LDD2133 
Serpin H1 (SERPINH1) LDTP04363 0.54  LDD2133 
SERPINE1 mRNA-binding protein 1 (SERBP1) LDTP09081 0.74  LDD2133 
Serrate RNA effector molecule homolog (SRRT) LDTP11398 1.26  LDD2133 
SH3 domain-containing kinase-binding protein 1 (SH3KBP1) LDTP10117 0.68  LDD2133 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 0.58  LDD2133 
Sister chromatid cohesion protein PDS5 homolog A (PDS5A) LDTP06684 0.96; 0.84  LDD2133 
Small nuclear ribonucleoprotein Sm D2 (SNRPD2) LDTP04982 0.61; 0.51  LDD2133 
Small nuclear ribonucleoprotein Sm D3 (SNRPD3) LDTP04983 0.57  LDD2133 
Small nuclear ribonucleoprotein-associated proteins B and B' (SNRPB) LDTP02741 0.42  LDD2133 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 0.71; 0.83; 1.01  LDD2133 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 1.06; 1.41; 0.70 ...  LDD2133 
Small ribosomal subunit protein eS17 (RPS17) LDTP02302 0.51  LDD2133 
Small ribosomal subunit protein eS21 (RPS21) LDTP05055 0.60  LDD2133 
Small ribosomal subunit protein eS25 (RPS25) LDTP05013 0.62  LDD2133 
Small ribosomal subunit protein eS26 (RPS26) LDTP05014 0.51  LDD2133 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 0.69  LDD2133 
Small ribosomal subunit protein eS6 (RPS6) LDTP05002 0.75  LDD2133 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 0.73; 0.56  LDD2133 
Small ribosomal subunit protein mS27 (MRPS27) LDTP09793 0.58  LDD2133 
Small ribosomal subunit protein mS35 (MRPS35) LDTP14788 0.44; 1.43  LDD2133 
Small ribosomal subunit protein uS10 (RPS20) LDTP04880 0.67  LDD2133 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 0.91  LDD2133 
Small ribosomal subunit protein uS2 (RPSA) LDTP02312 0.43  LDD2133 
Small ribosomal subunit protein uS2m (MRPS2) LDTP13961 0.77  LDD2133 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 0.63  LDD2133 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 0.70  LDD2133 
Small ribosomal subunit protein uS8 (RPS15A) LDTP04965 0.66  LDD2133 
Small ribosomal subunit protein uS9 (RPS16) LDTP04966 0.72  LDD2133 
Small subunit processome component 20 homolog (UTP20) LDTP01294 0.74; 0.96  LDD2133 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 0.48; 0.41; 0.46  LDD2133 
Sperm-associated antigen 5 (SPAG5) LDTP10753 0.49  LDD2133 
Spindle and kinetochore-associated protein 2 (SKA2) LDTP09612 0.65  LDD2133 
Splicing factor 1 (SF1) LDTP06429 0.74; 0.45  LDD2133 
Splicing factor 3B subunit 1 (SF3B1) LDTP01251 0.91; 1.63; 0.42  LDD2133 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 0.67; 0.91  LDD2133 
Splicing factor 3B subunit 6 (SF3B6) LDTP13970 0.76  LDD2133 
Splicing factor 45 (RBM17) LDTP10409 0.75  LDD2133 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 0.88; 0.55  LDD2133 
Squamous cell carcinoma antigen recognized by T-cells 3 (SART3) LDTP06280 0.55  LDD2133 
Src substrate cortactin (CTTN) LDTP06094 0.59  LDD2133 
Stalled ribosome sensor GCN1 (GCN1) LDTP09821 0.56; 0.45  LDD2133 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 0.47; 0.83; 0.51  LDD2133 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 0.62; 1.02; 0.48 ...  LDD2133 
Structural maintenance of chromosomes protein 3 (SMC3) LDTP13760 0.44  LDD2133 
Symplekin (SYMPK) LDTP09878 0.73  LDD2133 
Synembryn-A (RIC8A) LDTP12381 0.70  LDD2133 
Syntaxin-16 (STX16) LDTP00401 0.50  LDD2133 
Syntaxin-7 (STX7) LDTP00632 0.67  LDD2133 
T-complex protein 1 subunit alpha (TCP1) LDTP02934 0.79; 0.70  LDD2133 
T-complex protein 1 subunit beta (CCT2) LDTP05113 0.53  LDD2133 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 1.29; 0.70; 0.66 ...  LDD2133 
T-complex protein 1 subunit eta (CCT7) LDTP10990 0.92; 0.73; 0.55 ...  LDD2133 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 0.58; 0.55; 0.64 ...  LDD2133 
T-complex protein 1 subunit theta (CCT8) LDTP04390 0.45; 0.58; 0.83  LDD2133 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 0.39  LDD2133 
TAR DNA-binding protein 43 (TARDBP) LDTP05767 1.44  LDD2133 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 0.65  LDD2133 
Tenascin (TNC) LDTP03292 0.56  LDD2133 
Tetraspanin-4 (TSPAN4) LDTP00448 1.06  LDD2133 
Tetratricopeptide repeat protein 1 (TTC1) LDTP15840 0.59  LDD2133 
Tetratricopeptide repeat protein 4 (TTC4) LDTP01678 0.64  LDD2133 
THUMP domain-containing protein 1 (THUMPD1) LDTP12780 0.57; 0.80  LDD2133 
Transcription elongation factor A protein-like 4 (TCEAL4) LDTP18149 0.43  LDD2133 
Transcription initiation factor IIA subunit 2 (GTF2A2) LDTP04517 0.73  LDD2133 
Transforming acidic coiled-coil-containing protein 1 (TACC1) LDTP01210 0.88  LDD2133 
Transgelin-2 (TAGLN2) LDTP03846 0.86  LDD2133 
Translation initiation factor eIF2B subunit alpha (EIF2B1) LDTP06088 0.58  LDD2133 
Translationally-controlled tumor protein (TPT1) LDTP02683 0.46; 0.81  LDD2133 
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (TRMT6) LDTP13381 1.23  LDD2133 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 0.86  LDD2133 
Tubulin beta chain (TUBB) LDTP02205 0.58  LDD2133 
Tubulin-folding cofactor B (TBCB) LDTP10860 0.59; 0.46  LDD2133 
Tubulin-specific chaperone A (TBCA) LDTP01184 1.00  LDD2133 
Tumor protein D54 (TPD52L2) LDTP00759 0.86  LDD2133 
Twinfilin-2 (TWF2) LDTP07404 0.58  LDD2133 
U1 small nuclear ribonucleoprotein C (SNRPC) LDTP02335 0.73  LDD2133 
U2 snRNP-associated SURP motif-containing protein (U2SURP) LDTP00517 0.66  LDD2133 
U4/U6 small nuclear ribonucleoprotein Prp31 (PRPF31) LDTP09671 0.61  LDD2133 
Ubiquitin-like protein 5 (UBL5) LDTP11545 0.69; 1.15  LDD2133 
UBX domain-containing protein 1 (UBXN1) LDTP05418 0.58  LDD2133 
Urokinase plasminogen activator surface receptor (PLAUR) LDTP05404 0.52; 0.80  LDD2133 
Vigilin (HDLBP) LDTP05239 0.42; 0.59  LDD2133 
Vimentin (VIM) LDTP02297 0.45  LDD2133 
Vinculin (VCL) LDTP02946 0.37; 0.73; 0.58 ...  LDD2133 
WD repeat-containing protein 1 (WDR1) LDTP01118 0.64; 0.70  LDD2133 
WD repeat-containing protein 43 (WDR43) LDTP06305 0.89; 0.72  LDD2133 
WD40 repeat-containing protein SMU1 (SMU1) LDTP06726 0.59; 0.98  LDD2133 
WW domain-containing adapter protein with coiled-coil (WAC) LDTP11191 0.35  LDD2133 
Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) LDTP08018 0.73  LDD2133 
Zinc finger CCCH-type antiviral protein 1-like (ZC3HAV1L) LDTP18166 0.36  LDD2133 
Zinc finger RNA-binding protein (ZFR) LDTP15762 0.55; 0.70; 0.71  LDD2133 
Zyxin (ZYX) LDTP06507 0.60; 0.57  LDD2133 
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Full Information of The Labelling Profiles of This Competitor

Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 5 mM
Quantitative Method Isotope tag
Experimemt Name ISO-TOP ABPP
Competitor Name Nucleophilic fragment 35
Competitor Concentration 0.5 mM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cell lysate (MDA-MB-231)
Interaction Atlas ID  LDD2133  Download The Altas

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761