Details of the Target

General Information of Target

Target ID LDTP06103
Target Name Filamin-C (FLNC)
Gene Name FLNC
Gene ID 2318
Synonyms
ABPL; FLN2; Filamin-C; FLN-C; FLNc; ABP-280-like protein; ABP-L; Actin-binding-like protein; Filamin-2; Gamma-filamin
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDL
QRDLSDGLRLIALLEVLSQKRMYRKFHPRPNFRQMKLENVSVALEFLEREHIKLVSIDSK
AIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEI
VDPNVDEHSVMTYLSQFPKAKLKPGAPVRSKQLNPKKAIAYGPGIEPQGNTVLQPAHFTV
QTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGR
RDTVEVALEDKGDSTFRCTYRPAMEGPHTVHVAFAGAPITRSPFPVHVSEACNPNACRAS
GRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTE
VGTLGFSIEGPSQAKIECDDKGDGSCDVRYWPTEPGEYAVHVICDDEDIRDSPFIAHILP
APPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLK
ANEPTYFTVDCSEAGQGDVSIGIKCAPGVVGPAEADIDFDIIKNDNDTFTVKYTPPGAGR
YTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNV
APPLDLSKIKVQGLNSKVAVGQEQAFSVNTRGAGGQGQLDVRMTSPSRRPIPCKLEPGGG
AEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHI
PGSPFKATIRPVFDPSKVRASGPGLERGKVGEAATFTVDCSEAGEAELTIEILSDAGVKA
EVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYE
EGVHLVEVLYDEVAVPKSPFRVGVTEGCDPTRVRAFGPGLEGGLVNKANRFTVETRGAGT
GGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGT
HTVHYTPATDGPYTVAVKYADQEVPRSPFKIKVLPAHDASKVRASGPGLNASGIPASLPV
EFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTC
TVSTPDGAELDVDVVENHDGTFDIYYTAPEPGKYVITIRFGGEHIPNSPFHVLACDPLPH
EEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG
EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSR
HVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLP
TAPGDYSIIVRFDDKHIPGSPFTAKITGDDSMRTSQLNVGTSTDVSLKITESDLSQLTAS
IRAPSGNEEPCLLKRLPNRHIGISFTPKEVGEHVVSVRKSGKHVTNSPFKILVGPSEIGD
ASKVRVWGKGLSEGHTFQVAEFIVDTRNAGYGGLGLSIEGPSKVDINCEDMEDGTCKVTY
CPTEPGTYIINIKFADKHVPGSPFTVKVTGEGRMKESITRRRQAPSIATIGSTCDLNLKI
PGNWFQMVSAQERLTRTFTRSSHTYTRTERTEISKTRGGETKREVRVEESTQVGGDPFPA
VFGDFLGRERLGSFGSITRQQEGEASSQDMTAQVTSPSGKVEAAEIVEGEDSAYSVRFVP
QEMGPHTVAVKYRGQHVPGSPFQFTVGPLGEGGAHKVRAGGTGLERGVAGVPAEFSIWTR
EAGAGGLSIAVEGPSKAEIAFEDRKDGSCGVSYVVQEPGDYEVSIKFNDEHIPDSPFVVP
VASLSDDARRLTVTSLQETGLKVNQPASFAVQLNGARGVIDARVHTPSGAVEECYVSELD
SDKHTIRFIPHENGVHSIDVKFNGAHIPGSPFKIRVGEQSQAGDPGLVSAYGPGLEGGTT
GVSSEFIVNTLNAGSGALSVTIDGPSKVQLDCRECPEGHVVTYTPMAPGNYLIAIKYGGP
QHIVGSPFKAKVTGPRLSGGHSLHETSTVLVETVTKSSSSRGSSYSSIPKFSSDASKVVT
RGPGLSQAFVGQKNSFTVDCSKAGTNMMMVGVHGPKTPCEEVYVKHMGNRVYNVTYTVKE
KGDYILIVKWGDESVPGSPFKVKVP
Target Bioclass
Transporter and channel
Family
Filamin family
Subcellular location
Cytoplasm
Function
Muscle-specific filamin, which plays a central role in sarcomere assembly and organization. Critical for normal myogenesis, it probably functions as a large actin-cross-linking protein with structural functions at the Z lines in muscle cells. May be involved in reorganizing the actin cytoskeleton in response to signaling events.
Uniprot ID
Q14315
Ensemble ID
ENST00000325888.13
HGNC ID
HGNC:3756

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A2058 SNV: p.I2110V DBIA    Probe Info 
BT549 SNV: p.T2107A DBIA    Probe Info 
CCK81 SNV: p.R2173C DBIA    Probe Info 
COLO678 SNV: p.A2263T DBIA    Probe Info 
CORL23 SNV: p.V1446L DBIA    Probe Info 
EFO27 SNV: p.C1013Y DBIA    Probe Info 
G415 SNV: p.F2114L DBIA    Probe Info 
HCC1187 SNV: p.D205Y DBIA    Probe Info 
HCC1937 SNV: p.V245M DBIA    Probe Info 
HCT116 SNV: p.H1740Y DBIA    Probe Info 
HCT15 SNV: p.K1337N; p.A1887T DBIA    Probe Info 
HG3 SNV: p.G2506S DBIA    Probe Info 
HT SNV: p.T1921I DBIA    Probe Info 
HT1080 Deletion: p.V215WfsTer37 DBIA    Probe Info 
HT115 SNV: p.R164W; p.D827N DBIA    Probe Info 
IGROV1 Insertion: p.R1426AfsTer85
SNV: p.P1358S		 DBIA    Probe Info 
IPC298 SNV: p.G1548D; p.D2389N DBIA    Probe Info 
JURKAT SNV: p.V1930M; p.R2277C .
KYSE30 SNV: p.T1913N DBIA    Probe Info 
KYSE410 SNV: p.E637K DBIA    Probe Info 
LN18 SNV: p.P200S DBIA    Probe Info 
MEWO SNV: p.P363S; p.P1062S; p.P1080L; p.D1964N DBIA    Probe Info 
NALM6 SNV: p.A193T; p.E286K DBIA    Probe Info 
NCIH1048 SNV: p.A1247E DBIA    Probe Info 
NCIH1155 SNV: p.R2187H DBIA    Probe Info 
NCIH1703 SNV: p.Y1028C DBIA    Probe Info 
NCIH2291 SNV: p.P1414S DBIA    Probe Info 
NCIH3122 SNV: p.D2085N DBIA    Probe Info 
NCIH358 SNV: p.S2016R DBIA    Probe Info 
OAW42 SNV: p.S1644Y DBIA    Probe Info 
OCUG1 SNV: p.T1913N DBIA    Probe Info 
ONS76 SNV: p.H2582Q DBIA    Probe Info 
SNGM SNV: p.L64I; p.K1910N DBIA    Probe Info 
SUDHL6 SNV: p.Y730S .
SW1116 SNV: p.S2181T DBIA    Probe Info 
SW1271 SNV: p.P204L DBIA    Probe Info 
SW837 SNV: p.G1649C DBIA    Probe Info 
SW948 SNV: p.P1581S DBIA    Probe Info 
TOV21G SNV: p.H865N; p.V1576I DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 23 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		5.58  LDD0402  [1]
A-EBA
 Probe Info  		2.98  LDD0215  [2]
CY-1
 Probe Info  		100.00  LDD0243  [3]
CY4
 Probe Info  		100.00  LDD0244  [3]
N1
 Probe Info  		100.00  LDD0242  [3]
ONAyne
 Probe Info  		K1299(5.56); K1367(8.97); K1438(2.98); K1935(8.39)  LDD0274  [4]
STPyne
 Probe Info  		K1073(10.00); K113(7.83); K1237(1.18); K1254(3.34)  LDD0277  [4]
IPM
 Probe Info  		N.A.  LDD0241  [5]
BTD
 Probe Info  		C1991(2.34); C2660(2.32); C1348(2.32); C2552(2.28)  LDD1700  [6]
AHL-Pu-1
 Probe Info  		C626(2.23); C618(2.02)  LDD0168  [7]
HHS-465
 Probe Info  		Y2185(8.44); Y926(10.00)  LDD2237  [8]
DBIA
 Probe Info  		C1348(1.14); C618(1.07); C626(1.07); C1066(1.01)  LDD0078  [9]
ATP probe
 Probe Info  		N.A.  LDD0199  [10]
IA-alkyne
 Probe Info  		C618(0.00); C2555(0.00)  LDD0032  [11]
NAIA_4
 Probe Info  		N.A.  LDD2226  [12]
1d-yne
 Probe Info  		N.A.  LDD0356  [13]
PPMS
 Probe Info  		C1103(0.00); C1991(0.00)  LDD0008  [14]
SF
 Probe Info  		N.A.  LDD0028  [15]
1c-yne
 Probe Info  		N.A.  LDD0228  [13]
Acrolein
 Probe Info  		C618(0.00); C1103(0.00); C1991(0.00); C46(0.00)  LDD0217  [16]
Cinnamaldehyde
 Probe Info  		N.A.  LDD0220  [16]
Crotonaldehyde
 Probe Info  		C618(0.00); C1103(0.00); C46(0.00); H49(0.00)  LDD0219  [16]
Methacrolein
 Probe Info  		C1103(0.00); C618(0.00); C1991(0.00); C626(0.00)  LDD0218  [16]
PAL-AfBPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe14
 Probe Info  		20.00  LDD0477  [17]
JN0003
 Probe Info  		20.00  LDD0469  [17]
STS-2
 Probe Info  		N.A.  LDD0138  [18]
DA-2
 Probe Info  		N.A.  LDD0070  [19]
STS-1
 Probe Info  		N.A.  LDD0068  [20]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C728(0.48); C2679(0.56); C1348(0.26); C1066(0.66)  LDD2142  [6]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C1448(0.55); C2454(0.69); C2679(0.72); C1348(0.36)  LDD2112  [6]
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C728(0.86); C1448(0.76); C1906(0.74); C2660(0.71)  LDD2095  [6]
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C728(1.48); C1448(1.11); C2660(0.77); C2454(0.89)  LDD2130  [6]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C728(1.21); C1448(0.85); C1906(1.07); C2660(1.36)  LDD2117  [6]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C728(1.18); C1448(0.83); C1906(1.15); C2660(1.26)  LDD2152  [6]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C2679(0.94); C1066(0.93); C2154(1.11); C1013(1.53)  LDD2103  [6]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C728(0.80); C1448(0.31); C2454(0.76); C2679(0.55)  LDD2132  [6]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C728(0.88); C1448(0.90); C2660(1.18); C2679(0.98)  LDD2131  [6]
 LDCM0025  4SU-RNA HEK-293T C626(2.23); C618(2.02)  LDD0168  [7]
 LDCM0026  4SU-RNA+native RNA HEK-293T C626(2.31); C618(2.16)  LDD0169  [7]
 LDCM0214  AC1 HCT 116 C1066(1.47); C1103(1.54); C1348(1.13); C2088(0.97)  LDD0531  [9]
 LDCM0215  AC10 HCT 116 C1066(0.91); C1103(1.04); C2154(0.83); C2369(1.16)  LDD0532  [9]
 LDCM0216  AC100 HCT 116 C1066(0.78); C1103(0.95); C1348(0.79); C1448(0.61)  LDD0533  [9]
 LDCM0217  AC101 HCT 116 C1066(0.83); C1103(1.04); C1348(0.76); C1448(0.86)  LDD0534  [9]
 LDCM0218  AC102 HCT 116 C1066(0.84); C1103(0.92); C1348(0.97); C1448(0.51)  LDD0535  [9]
 LDCM0219  AC103 HCT 116 C1066(0.93); C1103(0.73); C1348(0.68); C1448(0.78)  LDD0536  [9]
 LDCM0220  AC104 HCT 116 C1066(0.87); C1103(0.70); C1348(0.73); C1448(0.67)  LDD0537  [9]
 LDCM0221  AC105 HCT 116 C1066(0.85); C1103(0.82); C1348(0.84); C1448(0.92)  LDD0538  [9]
 LDCM0222  AC106 HCT 116 C1066(0.89); C1103(0.66); C1348(0.72); C1448(0.78)  LDD0539  [9]
 LDCM0223  AC107 HCT 116 C1066(0.86); C1103(0.61); C1348(0.81); C1448(1.03)  LDD0540  [9]
 LDCM0224  AC108 HCT 116 C1066(0.91); C1103(0.58); C1348(0.81); C1448(0.57)  LDD0541  [9]
 LDCM0225  AC109 HCT 116 C1066(0.82); C1103(0.57); C1348(0.62); C1448(0.77)  LDD0542  [9]
 LDCM0226  AC11 HCT 116 C1066(0.94); C1103(1.03); C2154(0.85); C2369(1.21)  LDD0543  [9]
 LDCM0227  AC110 HCT 116 C1066(0.84); C1103(0.48); C1348(0.86); C1448(0.45)  LDD0544  [9]
 LDCM0228  AC111 HCT 116 C1066(0.85); C1103(0.82); C1348(0.88); C1448(0.55)  LDD0545  [9]
 LDCM0229  AC112 HCT 116 C1066(0.86); C1103(0.69); C1348(0.67); C1448(0.81)  LDD0546  [9]
 LDCM0230  AC113 HCT 116 C1066(1.17); C1103(1.22); C1348(1.05); C2088(0.66)  LDD0547  [9]
 LDCM0231  AC114 HCT 116 C1066(1.12); C1103(0.97); C1348(1.06); C2088(0.89)  LDD0548  [9]
 LDCM0232  AC115 HCT 116 C1066(1.17); C1103(0.89); C1348(1.27); C2088(0.69)  LDD0549  [9]
 LDCM0233  AC116 HCT 116 C1066(1.14); C1103(1.08); C1348(1.33); C2088(0.79)  LDD0550  [9]
 LDCM0234  AC117 HCT 116 C1066(1.18); C1103(0.93); C1348(1.33); C2088(0.73)  LDD0551  [9]
 LDCM0235  AC118 HCT 116 C1066(1.08); C1103(1.23); C1348(1.22); C2088(0.88)  LDD0552  [9]
 LDCM0236  AC119 HCT 116 C1066(1.17); C1103(1.10); C1348(1.27); C2088(0.88)  LDD0553  [9]
 LDCM0237  AC12 HCT 116 C1066(0.85); C1103(1.05); C2154(0.93); C2369(1.13)  LDD0554  [9]
 LDCM0238  AC120 HCT 116 C1066(1.03); C1103(1.33); C1348(1.04); C2088(0.63)  LDD0555  [9]
 LDCM0239  AC121 HCT 116 C1066(0.95); C1103(1.02); C1348(1.09); C2088(0.60)  LDD0556  [9]
 LDCM0240  AC122 HCT 116 C1066(1.01); C1103(1.21); C1348(0.99); C2088(1.16)  LDD0557  [9]
 LDCM0241  AC123 HCT 116 C1066(0.95); C1103(0.85); C1348(1.13); C2088(0.88)  LDD0558  [9]
 LDCM0242  AC124 HCT 116 C1066(1.07); C1103(1.14); C1348(1.01); C2088(0.65)  LDD0559  [9]
 LDCM0243  AC125 HCT 116 C1066(1.00); C1103(1.33); C1348(1.10); C2088(0.87)  LDD0560  [9]
 LDCM0244  AC126 HCT 116 C1066(1.00); C1103(1.28); C1348(1.02); C2088(1.01)  LDD0561  [9]
 LDCM0245  AC127 HCT 116 C1066(1.04); C1103(1.17); C1348(1.07); C2088(0.81)  LDD0562  [9]
 LDCM0246  AC128 HCT 116 C1066(1.13); C1348(1.21); C1448(1.92); C2088(1.24)  LDD0563  [9]
 LDCM0247  AC129 HCT 116 C1066(1.27); C1348(1.03); C1448(0.98); C2088(1.87)  LDD0564  [9]
 LDCM0249  AC130 HCT 116 C1066(1.34); C1348(1.64); C1448(1.32); C2088(1.51)  LDD0566  [9]
 LDCM0250  AC131 HCT 116 C1066(1.13); C1348(0.86); C1448(1.02); C2088(1.33)  LDD0567  [9]
 LDCM0251  AC132 HCT 116 C1066(1.12); C1348(1.52); C1448(1.98); C2088(1.16)  LDD0568  [9]
 LDCM0252  AC133 HCT 116 C1066(1.29); C1348(1.38); C1448(2.08); C2088(1.25)  LDD0569  [9]
 LDCM0253  AC134 HCT 116 C1066(1.00); C1348(1.40); C1448(1.48); C2088(1.55)  LDD0570  [9]
 LDCM0254  AC135 HCT 116 C1066(1.19); C1348(1.40); C1448(2.37); C2088(1.81)  LDD0571  [9]
 LDCM0255  AC136 HCT 116 C1066(1.10); C1348(1.04); C1448(1.20); C2088(1.12)  LDD0572  [9]
 LDCM0256  AC137 HCT 116 C1066(1.23); C1348(1.05); C1448(1.74); C2088(0.91)  LDD0573  [9]
 LDCM0257  AC138 HCT 116 C1066(1.24); C1348(1.42); C1448(1.74); C2088(1.52)  LDD0574  [9]
 LDCM0258  AC139 HCT 116 C1066(1.32); C1348(1.32); C1448(1.85); C2088(1.18)  LDD0575  [9]
 LDCM0259  AC14 HCT 116 C1066(0.89); C1103(1.22); C2154(0.84); C2369(1.01)  LDD0576  [9]
 LDCM0260  AC140 HCT 116 C1066(1.19); C1348(1.46); C1448(2.10); C2088(1.35)  LDD0577  [9]
 LDCM0261  AC141 HCT 116 C1066(1.01); C1348(1.22); C1448(1.43); C2088(1.27)  LDD0578  [9]
 LDCM0262  AC142 HCT 116 C1066(1.31); C1348(1.09); C1448(1.27); C2088(1.12)  LDD0579  [9]
 LDCM0263  AC143 HCT 116 C1066(1.04); C1103(0.99); C1348(0.97); C1448(1.09)  LDD0580  [9]
 LDCM0264  AC144 HCT 116 C46(0.71); C2679(0.77); C198(0.77); C203(0.77)  LDD0581  [9]
 LDCM0265  AC145 HCT 116 C198(0.69); C203(0.69); C46(0.78); C1348(0.89)  LDD0582  [9]
 LDCM0266  AC146 HCT 116 C198(0.53); C203(0.53); C46(0.80); C618(0.99)  LDD0583  [9]
 LDCM0267  AC147 HCT 116 C198(0.47); C203(0.47); C46(0.74); C618(0.80)  LDD0584  [9]
 LDCM0268  AC148 HCT 116 C198(0.53); C203(0.53); C46(0.75); C626(1.01)  LDD0585  [9]
 LDCM0269  AC149 HCT 116 C198(0.47); C203(0.47); C46(0.76); C618(0.85)  LDD0586  [9]
 LDCM0270  AC15 HCT 116 C2679(0.87); C2154(0.88); C1066(0.89); C46(0.90)  LDD0587  [9]
 LDCM0271  AC150 HCT 116 C46(0.88); C618(0.89); C626(0.95); C1066(0.99)  LDD0588  [9]
 LDCM0272  AC151 HCT 116 C198(0.59); C203(0.59); C46(0.91); C2369(1.02)  LDD0589  [9]
 LDCM0273  AC152 HCT 116 C198(0.52); C203(0.52); C46(0.87); C2154(0.94)  LDD0590  [9]
 LDCM0274  AC153 HCT 116 C198(0.47); C203(0.47); C46(0.86); C618(1.05)  LDD0591  [9]
 LDCM0621  AC154 HCT 116 C1066(1.22); C1103(1.29); C1348(0.77); C1448(1.48)  LDD2158  [9]
 LDCM0622  AC155 HCT 116 C1066(1.06); C1103(1.67); C1348(1.04); C1448(1.12)  LDD2159  [9]
 LDCM0623  AC156 HCT 116 C1066(0.97); C1103(1.17); C1348(0.85); C1448(1.22)  LDD2160  [9]
 LDCM0624  AC157 HCT 116 C1066(1.30); C1103(1.34); C1348(0.94); C1448(1.03)  LDD2161  [9]
 LDCM0276  AC17 HCT 116 C618(0.92); C1348(1.00); C626(1.01); C46(1.02)  LDD0593  [9]
 LDCM0277  AC18 HCT 116 C2154(0.80); C1448(0.88); C2679(1.00); C46(1.01)  LDD0594  [9]
 LDCM0278  AC19 HCT 116 C46(0.86); C2154(0.95); C618(1.00); C1103(1.00)  LDD0595  [9]
 LDCM0279  AC2 HCT 116 C2679(0.82); C46(0.87); C2088(0.96); C2096(0.96)  LDD0596  [9]
 LDCM0280  AC20 HCT 116 C1103(0.84); C1348(0.85); C1066(0.91); C535(0.91)  LDD0597  [9]
 LDCM0281  AC21 HCT 116 C2154(0.93); C2679(0.94); C2369(1.01); C1348(1.10)  LDD0598  [9]
 LDCM0282  AC22 HCT 116 C2154(0.95); C2369(0.98); C2679(1.00); C46(1.00)  LDD0599  [9]
 LDCM0283  AC23 HCT 116 C2154(0.88); C46(0.90); C2369(0.92); C2679(0.93)  LDD0600  [9]
 LDCM0284  AC24 HCT 116 C46(0.82); C2679(0.89); C1103(0.90); C618(0.96)  LDD0601  [9]
 LDCM0285  AC25 HCT 116 C2088(0.68); C2096(0.68); C626(0.93); C46(0.93)  LDD0602  [9]
 LDCM0286  AC26 HCT 116 C535(0.40); C2088(0.69); C2096(0.69); C46(0.70)  LDD0603  [9]
 LDCM0287  AC27 HCT 116 C535(0.41); C2088(0.65); C2096(0.65); C46(0.70)  LDD0604  [9]
 LDCM0288  AC28 HCT 116 C535(0.39); C2088(0.64); C2096(0.64); C46(0.70)  LDD0605  [9]
 LDCM0289  AC29 HCT 116 C535(0.26); C2088(0.57); C2096(0.57); C46(0.59)  LDD0606  [9]
 LDCM0290  AC3 HCT 116 C2679(0.95); C46(1.01); C2369(1.05); C535(1.13)  LDD0607  [9]
 LDCM0291  AC30 HCT 116 C535(0.24); C46(0.67); C626(0.88); C2088(0.91)  LDD0608  [9]
 LDCM0292  AC31 HCT 116 C535(0.37); C46(0.67); C2088(0.76); C2096(0.76)  LDD0609  [9]
 LDCM0293  AC32 HCT 116 C535(0.26); C2088(0.58); C2096(0.58); C46(0.58)  LDD0610  [9]
 LDCM0294  AC33 HCT 116 C535(0.60); C46(0.61); C2088(0.75); C2096(0.75)  LDD0611  [9]
 LDCM0295  AC34 HCT 116 C535(0.41); C2088(0.57); C2096(0.57); C46(0.60)  LDD0612  [9]
 LDCM0296  AC35 HCT 116 C2660(0.86); C1066(0.90); C2088(0.96); C2096(0.96)  LDD0613  [9]
 LDCM0297  AC36 HCT 116 C2679(0.70); C2369(0.89); C2660(0.94); C1066(0.97)  LDD0614  [9]
 LDCM0298  AC37 HCT 116 C2154(0.85); C2660(0.92); C1066(0.96); C2679(1.04)  LDD0615  [9]
 LDCM0299  AC38 HCT 116 C1066(0.84); C2369(0.87); C2154(0.89); C2660(0.98)  LDD0616  [9]
 LDCM0300  AC39 HCT 116 C2679(0.87); C2154(0.88); C2369(0.90); C46(0.95)  LDD0617  [9]
 LDCM0301  AC4 HCT 116 C2088(0.79); C2096(0.79); C2679(0.98); C2154(1.04)  LDD0618  [9]
 LDCM0302  AC40 HCT 116 C2660(0.88); C2154(0.93); C46(1.07); C1066(1.13)  LDD0619  [9]
 LDCM0303  AC41 HCT 116 C2369(0.92); C2154(0.98); C2660(0.98); C2679(1.00)  LDD0620  [9]
 LDCM0304  AC42 HCT 116 C2154(0.84); C535(0.86); C2679(0.89); C46(0.90)  LDD0621  [9]
 LDCM0305  AC43 HCT 116 C2154(0.86); C46(0.92); C2660(0.98); C2679(1.00)  LDD0622  [9]
 LDCM0306  AC44 HCT 116 C2154(0.89); C2660(0.96); C46(1.04); C2369(1.07)  LDD0623  [9]
 LDCM0307  AC45 HCT 116 C2154(0.85); C2660(0.88); C2088(1.10); C2096(1.10)  LDD0624  [9]
 LDCM0308  AC46 HCT 116 C535(0.47); C1066(0.83); C2369(0.86); C1348(0.92)  LDD0625  [9]
 LDCM0309  AC47 HCT 116 C535(0.63); C618(0.85); C1066(0.88); C2369(0.90)  LDD0626  [9]
 LDCM0310  AC48 HCT 116 C535(0.41); C1066(0.77); C2154(0.89); C618(0.97)  LDD0627  [9]
 LDCM0311  AC49 HCT 116 C535(0.36); C618(0.74); C2660(0.81); C2154(0.82)  LDD0628  [9]
 LDCM0312  AC5 HCT 116 C2088(0.84); C2096(0.84); C2679(0.95); C1348(1.03)  LDD0629  [9]
 LDCM0313  AC50 HCT 116 C535(0.37); C1066(0.81); C618(0.86); C46(0.87)  LDD0630  [9]
 LDCM0314  AC51 HCT 116 C535(0.34); C2369(0.76); C1348(0.79); C2679(0.84)  LDD0631  [9]
 LDCM0315  AC52 HCT 116 C535(0.44); C1066(0.78); C2679(0.84); C1348(0.90)  LDD0632  [9]
 LDCM0316  AC53 HCT 116 C535(0.50); C618(0.73); C46(0.82); C2154(0.86)  LDD0633  [9]
 LDCM0317  AC54 HCT 116 C535(0.48); C1066(0.72); C618(0.81); C2660(0.89)  LDD0634  [9]
 LDCM0318  AC55 HCT 116 C1066(0.74); C46(0.84); C2660(0.88); C535(0.91)  LDD0635  [9]
 LDCM0319  AC56 HCT 116 C535(0.51); C2154(0.78); C2660(0.80); C1066(0.93)  LDD0636  [9]
 LDCM0320  AC57 HCT 116 C2154(0.61); C1348(0.77); C46(0.87); C2679(1.06)  LDD0637  [9]
 LDCM0321  AC58 HCT 116 C2154(0.65); C46(0.81); C626(0.97); C2369(0.98)  LDD0638  [9]
 LDCM0322  AC59 HCT 116 C2154(0.56); C46(0.83); C626(1.00); C1348(1.05)  LDD0639  [9]
 LDCM0323  AC6 HCT 116 C2369(0.85); C2154(0.89); C46(1.00); C1066(1.06)  LDD0640  [9]
 LDCM0324  AC60 HCT 116 C2154(0.49); C2088(0.89); C2096(0.89); C1348(0.98)  LDD0641  [9]
 LDCM0325  AC61 HCT 116 C2154(0.51); C1348(0.68); C618(0.97); C46(1.11)  LDD0642  [9]
 LDCM0326  AC62 HCT 116 C2154(0.60); C46(0.80); C1348(0.89); C2088(1.08)  LDD0643  [9]
 LDCM0327  AC63 HCT 116 C1348(0.59); C2154(0.62); C2088(0.91); C2096(0.91)  LDD0644  [9]
 LDCM0328  AC64 HCT 116 C2154(0.51); C1348(0.90); C46(0.94); C2088(1.06)  LDD0645  [9]
 LDCM0329  AC65 HCT 116 C2154(0.54); C618(0.84); C626(0.85); C46(0.85)  LDD0646  [9]
 LDCM0330  AC66 HCT 116 C2154(0.58); C618(0.76); C626(0.82); C46(0.88)  LDD0647  [9]
 LDCM0331  AC67 HCT 116 C2154(0.44); C46(0.72); C626(0.74); C618(0.75)  LDD0648  [9]
 LDCM0332  AC68 HCT 116 C2088(0.74); C2096(0.74); C618(0.84); C2154(0.90)  LDD0649  [9]
 LDCM0333  AC69 HCT 116 C2679(0.67); C618(0.73); C1066(0.79); C2088(0.82)  LDD0650  [9]
 LDCM0334  AC7 HCT 116 C2154(0.83); C2679(0.86); C1066(0.96); C2369(0.98)  LDD0651  [9]
 LDCM0335  AC70 HCT 116 C618(0.53); C2088(0.61); C2096(0.61); C198(0.66)  LDD0652  [9]
 LDCM0336  AC71 HCT 116 C618(0.80); C198(0.83); C203(0.83); C626(0.87)  LDD0653  [9]
 LDCM0337  AC72 HCT 116 C1066(0.80); C618(0.86); C198(0.88); C203(0.88)  LDD0654  [9]
 LDCM0338  AC73 HCT 116 C198(0.54); C203(0.54); C618(0.69); C535(0.82)  LDD0655  [9]
 LDCM0339  AC74 HCT 116 C198(0.51); C203(0.51); C2088(0.53); C2096(0.53)  LDD0656  [9]
 LDCM0340  AC75 HCT 116 C198(0.52); C203(0.52); C535(0.74); C1066(0.74)  LDD0657  [9]
 LDCM0341  AC76 HCT 116 C198(0.65); C203(0.65); C2679(0.84); C2154(0.89)  LDD0658  [9]
 LDCM0342  AC77 HCT 116 C198(0.59); C203(0.59); C618(0.72); C1066(0.75)  LDD0659  [9]
 LDCM0343  AC78 HCT 116 C618(0.69); C1066(0.74); C2369(0.76); C2088(0.78)  LDD0660  [9]
 LDCM0344  AC79 HCT 116 C618(0.60); C626(0.76); C198(0.77); C203(0.77)  LDD0661  [9]
 LDCM0345  AC8 HCT 116 C2679(0.79); C2154(0.88); C2660(0.95); C46(0.96)  LDD0662  [9]
 LDCM0346  AC80 HCT 116 C198(0.68); C203(0.68); C2679(0.88); C2088(0.89)  LDD0663  [9]
 LDCM0347  AC81 HCT 116 C2088(0.71); C2096(0.71); C1448(0.72); C618(0.74)  LDD0664  [9]
 LDCM0348  AC82 HCT 116 C198(0.42); C203(0.42); C535(0.48); C618(0.60)  LDD0665  [9]
 LDCM0349  AC83 HCT 116 C46(0.74); C626(0.79); C535(0.79); C1448(0.86)  LDD0666  [9]
 LDCM0350  AC84 HCT 116 C46(0.79); C1448(0.83); C535(0.86); C626(0.98)  LDD0667  [9]
 LDCM0351  AC85 HCT 116 C1448(0.66); C535(0.70); C46(0.75); C626(0.83)  LDD0668  [9]
 LDCM0352  AC86 HCT 116 C46(0.62); C535(0.66); C626(0.81); C618(0.90)  LDD0669  [9]
 LDCM0353  AC87 HCT 116 C1448(0.79); C46(0.82); C535(0.89); C626(0.98)  LDD0670  [9]
 LDCM0354  AC88 HCT 116 C46(0.65); C535(0.71); C1448(0.77); C2369(0.79)  LDD0671  [9]
 LDCM0355  AC89 HCT 116 C46(0.61); C535(0.74); C626(0.87); C2369(0.88)  LDD0672  [9]
 LDCM0357  AC90 HCT 116 C535(0.65); C46(0.69); C2369(0.75); C1448(0.90)  LDD0674  [9]
 LDCM0358  AC91 HCT 116 C46(0.71); C1448(0.76); C535(0.85); C626(0.91)  LDD0675  [9]
 LDCM0359  AC92 HCT 116 C46(0.64); C1448(0.83); C535(0.86); C626(0.90)  LDD0676  [9]
 LDCM0360  AC93 HCT 116 C1448(0.68); C46(0.72); C535(0.74); C2369(0.79)  LDD0677  [9]
 LDCM0361  AC94 HCT 116 C1448(0.57); C626(0.95); C1103(0.97); C46(1.05)  LDD0678  [9]
 LDCM0362  AC95 HCT 116 C46(0.86); C2679(0.96); C1348(0.99); C626(1.14)  LDD0679  [9]
 LDCM0363  AC96 HCT 116 C1448(0.76); C2369(0.79); C46(0.86); C626(0.97)  LDD0680  [9]
 LDCM0364  AC97 HCT 116 C46(0.51); C535(0.64); C626(0.73); C1448(0.80)  LDD0681  [9]
 LDCM0365  AC98 HCT 116 C535(0.46); C46(0.55); C2369(0.62); C626(0.69)  LDD0682  [9]
 LDCM0366  AC99 HCT 116 C1448(0.55); C618(0.62); C626(0.70); C2369(0.71)  LDD0683  [9]
 LDCM0545  Acetamide MDA-MB-231 C1906(0.45); C2660(0.70); C2679(0.72); C1066(0.52)  LDD2138  [6]
 LDCM0520  AKOS000195272 MDA-MB-231 C728(0.87); C1448(1.20); C1906(0.69); C2660(0.86)  LDD2113  [6]
 LDCM0248  AKOS034007472 HCT 116 C1066(0.88); C1103(1.03); C2154(0.92); C2369(0.82)  LDD0565  [9]
 LDCM0356  AKOS034007680 HCT 116 C2679(0.71); C2154(0.81); C1066(0.88); C1103(1.03)  LDD0673  [9]
 LDCM0275  AKOS034007705 HCT 116 C2154(0.79); C46(1.02); C2679(1.08); C1066(1.09)  LDD0592  [9]
 LDCM0156  Aniline NCI-H1299 C712(0.00); C1448(0.00)  LDD0404  [1]
 LDCM0020  ARS-1620 HCC44 C1348(1.14); C618(1.07); C626(1.07); C1066(1.01)  LDD0078  [9]
 LDCM0498  BS-3668 MDA-MB-231 C728(0.95); C1448(1.64); C1906(0.47); C2660(1.21)  LDD2091  [6]
 LDCM0630  CCW28-3 231MFP C1109(1.22)  LDD2214  [21]
 LDCM0108  Chloroacetamide HeLa C1103(0.00); C618(0.00); C1991(0.00); C2660(0.00)  LDD0222  [16]
 LDCM0367  CL1 HCT 116 C2088(0.71); C2096(0.71); C535(0.72); C618(0.75)  LDD0684  [9]
 LDCM0368  CL10 HCT 116 C198(0.65); C203(0.65); C2088(0.84); C2096(0.84)  LDD0685  [9]
 LDCM0369  CL100 HCT 116 C46(0.89); C2088(0.91); C2096(0.91); C2679(0.97)  LDD0686  [9]
 LDCM0370  CL101 HCT 116 C2154(0.85); C2369(1.00); C618(1.00); C1066(1.07)  LDD0687  [9]
 LDCM0371  CL102 HCT 116 C2154(0.82); C1066(0.87); C618(0.88); C2369(1.02)  LDD0688  [9]
 LDCM0372  CL103 HCT 116 C2679(0.82); C2369(0.85); C1066(0.87); C1103(0.91)  LDD0689  [9]
 LDCM0373  CL104 HCT 116 C2679(0.84); C1066(0.88); C2154(0.88); C1103(0.96)  LDD0690  [9]
 LDCM0374  CL105 HCT 116 C2154(0.86); C46(0.96); C2679(1.02); C618(1.09)  LDD0691  [9]
 LDCM0375  CL106 HCT 116 C2154(0.73); C2679(0.99); C535(1.18); C2369(1.23)  LDD0692  [9]
 LDCM0376  CL107 HCT 116 C2154(0.80); C46(1.13); C2679(1.16); C535(1.16)  LDD0693  [9]
 LDCM0377  CL108 HCT 116 C2154(0.81); C618(0.90); C46(0.96); C626(0.97)  LDD0694  [9]
 LDCM0378  CL109 HCT 116 C2154(0.85); C46(0.88); C618(0.96); C1448(1.02)  LDD0695  [9]
 LDCM0379  CL11 HCT 116 C198(0.70); C203(0.70); C535(0.74); C2088(0.79)  LDD0696  [9]
 LDCM0380  CL110 HCT 116 C46(0.79); C2154(0.81); C535(0.92); C618(0.93)  LDD0697  [9]
 LDCM0381  CL111 HCT 116 C46(0.79); C2154(0.87); C618(0.98); C535(0.98)  LDD0698  [9]
 LDCM0382  CL112 HCT 116 C535(0.39); C46(0.63); C2088(0.64); C2096(0.64)  LDD0699  [9]
 LDCM0383  CL113 HCT 116 C535(0.23); C2088(0.57); C2096(0.57); C46(0.57)  LDD0700  [9]
 LDCM0384  CL114 HCT 116 C535(0.23); C46(0.55); C2088(0.83); C2096(0.83)  LDD0701  [9]
 LDCM0385  CL115 HCT 116 C535(0.27); C46(0.57); C2088(0.69); C2096(0.69)  LDD0702  [9]
 LDCM0386  CL116 HCT 116 C535(0.48); C2088(0.71); C2096(0.71); C46(0.75)  LDD0703  [9]
 LDCM0387  CL117 HCT 116 C2660(0.81); C2154(0.83); C46(1.00); C626(1.00)  LDD0704  [9]
 LDCM0388  CL118 HCT 116 C2154(0.80); C2660(0.98); C46(1.06); C1066(1.06)  LDD0705  [9]
 LDCM0389  CL119 HCT 116 C2154(0.91); C2660(0.94); C2369(0.97); C1348(1.05)  LDD0706  [9]
 LDCM0390  CL12 HCT 116 C198(0.60); C203(0.60); C535(0.65); C46(0.84)  LDD0707  [9]
 LDCM0391  CL120 HCT 116 C2154(0.98); C2369(0.99); C1348(1.00); C46(1.05)  LDD0708  [9]
 LDCM0392  CL121 HCT 116 C535(0.68); C2154(0.68); C2679(0.98); C2660(1.02)  LDD0709  [9]
 LDCM0393  CL122 HCT 116 C535(0.42); C618(0.72); C2154(0.86); C626(0.93)  LDD0710  [9]
 LDCM0394  CL123 HCT 116 C535(0.55); C618(0.72); C1066(0.77); C2660(0.84)  LDD0711  [9]
 LDCM0395  CL124 HCT 116 C535(0.54); C618(0.76); C46(0.85); C2660(0.86)  LDD0712  [9]
 LDCM0396  CL125 HCT 116 C2154(0.71); C1348(0.83); C618(0.84); C46(0.89)  LDD0713  [9]
 LDCM0397  CL126 HCT 116 C2154(0.58); C1448(0.85); C618(0.88); C626(0.94)  LDD0714  [9]
 LDCM0398  CL127 HCT 116 C2154(0.64); C2088(0.93); C2096(0.93); C618(0.98)  LDD0715  [9]
 LDCM0399  CL128 HCT 116 C2154(0.58); C46(0.89); C2088(1.01); C2096(1.01)  LDD0716  [9]
 LDCM0400  CL13 HCT 116 C198(0.70); C203(0.70); C2088(0.85); C2096(0.85)  LDD0717  [9]
 LDCM0401  CL14 HCT 116 C2369(0.73); C2088(0.80); C2096(0.80); C46(0.86)  LDD0718  [9]
 LDCM0402  CL15 HCT 116 C2679(0.60); C535(0.69); C198(0.84); C203(0.84)  LDD0719  [9]
 LDCM0403  CL16 HCT 116 C1348(0.62); C198(0.72); C203(0.72); C2369(0.81)  LDD0720  [9]
 LDCM0404  CL17 HCT 116 C198(0.62); C203(0.62); C1348(0.78); C535(0.89)  LDD0721  [9]
 LDCM0405  CL18 HCT 116 C198(0.87); C203(0.87); C2154(0.95); C1066(1.03)  LDD0722  [9]
 LDCM0406  CL19 HCT 116 C198(0.78); C203(0.78); C1348(0.82); C46(0.91)  LDD0723  [9]
 LDCM0407  CL2 HCT 116 C2369(0.72); C626(0.82); C2088(0.85); C2096(0.85)  LDD0724  [9]
 LDCM0408  CL20 HCT 116 C198(0.53); C203(0.53); C535(0.75); C46(0.81)  LDD0725  [9]
 LDCM0409  CL21 HCT 116 C198(0.59); C203(0.59); C2154(0.79); C46(0.83)  LDD0726  [9]
 LDCM0410  CL22 HCT 116 C198(0.46); C203(0.46); C46(0.84); C535(0.89)  LDD0727  [9]
 LDCM0411  CL23 HCT 116 C198(0.65); C203(0.65); C1348(0.69); C46(0.81)  LDD0728  [9]
 LDCM0412  CL24 HCT 116 C198(0.57); C203(0.57); C46(0.85); C535(0.86)  LDD0729  [9]
 LDCM0413  CL25 HCT 116 C1066(1.04); C1103(0.93); C1348(1.01); C198(0.55)  LDD0730  [9]
 LDCM0414  CL26 HCT 116 C1066(0.99); C1103(1.15); C1348(0.81); C198(0.70)  LDD0731  [9]
 LDCM0415  CL27 HCT 116 C1066(1.04); C1103(1.13); C1348(0.99); C198(0.63)  LDD0732  [9]
 LDCM0416  CL28 HCT 116 C1066(1.04); C1103(1.10); C1348(1.16); C198(0.80)  LDD0733  [9]
 LDCM0417  CL29 HCT 116 C1066(1.06); C1103(1.23); C1348(1.31); C198(0.76)  LDD0734  [9]
 LDCM0418  CL3 HCT 116 C1066(0.97); C1103(0.92); C1348(1.31); C198(0.98)  LDD0735  [9]
 LDCM0419  CL30 HCT 116 C1066(0.91); C1103(0.83); C1348(0.75); C198(0.63)  LDD0736  [9]
 LDCM0420  CL31 HCT 116 C1066(0.94); C1103(1.00); C1348(1.05); C2154(0.84)  LDD0737  [9]
 LDCM0421  CL32 HCT 116 C1066(0.91); C1103(1.19); C1348(1.45); C2154(0.82)  LDD0738  [9]
 LDCM0422  CL33 HCT 116 C1066(0.89); C1103(1.10); C1348(1.14); C2154(0.80)  LDD0739  [9]
 LDCM0423  CL34 HCT 116 C1066(0.86); C1103(1.06); C1348(1.16); C2154(0.86)  LDD0740  [9]
 LDCM0424  CL35 HCT 116 C1066(0.98); C1103(1.02); C1348(1.15); C2154(1.02)  LDD0741  [9]
 LDCM0425  CL36 HCT 116 C1066(0.84); C1103(1.02); C1348(1.07); C2154(1.06)  LDD0742  [9]
 LDCM0426  CL37 HCT 116 C1066(0.86); C1103(1.02); C1348(1.12); C2154(0.96)  LDD0743  [9]
 LDCM0428  CL39 HCT 116 C1066(0.88); C1103(0.98); C1348(0.91); C2154(0.99)  LDD0745  [9]
 LDCM0429  CL4 HCT 116 C1066(0.89); C1103(0.95); C1348(1.18); C198(0.76)  LDD0746  [9]
 LDCM0430  CL40 HCT 116 C1066(0.73); C1103(1.00); C1348(0.91); C2154(0.88)  LDD0747  [9]
 LDCM0431  CL41 HCT 116 C1066(0.88); C1103(0.99); C1348(1.17); C2154(0.95)  LDD0748  [9]
 LDCM0432  CL42 HCT 116 C1066(0.81); C1103(0.90); C1348(1.33); C2154(0.84)  LDD0749  [9]
 LDCM0433  CL43 HCT 116 C1066(0.77); C1103(0.93); C1348(1.16); C2154(0.91)  LDD0750  [9]
 LDCM0434  CL44 HCT 116 C1066(0.93); C1103(0.98); C1348(1.05); C2154(0.95)  LDD0751  [9]
 LDCM0435  CL45 HCT 116 C1066(0.89); C1103(1.01); C1348(1.07); C2154(0.98)  LDD0752  [9]
 LDCM0436  CL46 HCT 116 C1066(0.94); C1103(1.02); C1348(0.65); C2679(0.91)  LDD0753  [9]
 LDCM0437  CL47 HCT 116 C1066(0.84); C1103(0.89); C1348(0.73); C2679(0.89)  LDD0754  [9]
 LDCM0438  CL48 HCT 116 C1066(0.99); C1103(0.96); C1348(0.74); C2679(0.87)  LDD0755  [9]
 LDCM0439  CL49 HCT 116 C1066(0.91); C1103(0.99); C1348(0.82); C2679(0.93)  LDD0756  [9]
 LDCM0440  CL5 HCT 116 C1066(0.94); C1103(1.17); C1348(1.13); C198(1.03)  LDD0757  [9]
 LDCM0441  CL50 HCT 116 C1066(1.04); C1103(1.07); C1348(0.81); C2679(0.87)  LDD0758  [9]
 LDCM0442  CL51 HCT 116 C1066(0.91); C1103(0.82); C1348(0.68); C2679(0.88)  LDD0759  [9]
 LDCM0443  CL52 HCT 116 C1066(0.88); C1103(0.81); C1348(0.59); C2679(0.84)  LDD0760  [9]
 LDCM0444  CL53 HCT 116 C1066(0.93); C1103(0.84); C1348(0.78); C2679(0.78)  LDD0761  [9]
 LDCM0445  CL54 HCT 116 C1066(0.85); C1103(0.86); C1348(0.87); C2679(0.83)  LDD0762  [9]
 LDCM0446  CL55 HCT 116 C1066(0.76); C1103(0.86); C1348(0.63); C2679(0.82)  LDD0763  [9]
 LDCM0447  CL56 HCT 116 C1066(0.83); C1103(1.17); C1348(0.88); C2679(0.93)  LDD0764  [9]
 LDCM0448  CL57 HCT 116 C1066(1.02); C1103(1.00); C1348(0.86); C2679(0.82)  LDD0765  [9]
 LDCM0449  CL58 HCT 116 C1066(0.81); C1103(0.88); C1348(0.72); C2679(0.82)  LDD0766  [9]
 LDCM0450  CL59 HCT 116 C1066(0.82); C1103(0.96); C1348(0.75); C2679(0.89)  LDD0767  [9]
 LDCM0451  CL6 HCT 116 C1066(1.00); C1103(1.04); C1348(1.16); C198(0.77)  LDD0768  [9]
 LDCM0452  CL60 HCT 116 C1066(0.97); C1103(1.01); C1348(0.78); C2679(0.88)  LDD0769  [9]
 LDCM0453  CL61 HCT 116 C1066(0.69); C1103(1.05); C1348(0.82); C1448(1.01)  LDD0770  [9]
 LDCM0454  CL62 HCT 116 C1066(0.63); C1103(0.98); C1348(0.75); C1448(0.96)  LDD0771  [9]
 LDCM0455  CL63 HCT 116 C1066(0.77); C1103(1.09); C1348(0.93); C1448(1.01)  LDD0772  [9]
 LDCM0456  CL64 HCT 116 C1066(0.76); C1103(0.99); C1348(0.93); C1448(1.20)  LDD0773  [9]
 LDCM0457  CL65 HCT 116 C1066(0.67); C1103(1.06); C1348(0.71); C1448(1.21)  LDD0774  [9]
 LDCM0458  CL66 HCT 116 C1066(0.88); C1103(1.17); C1348(0.99); C1448(1.22)  LDD0775  [9]
 LDCM0459  CL67 HCT 116 C1066(0.67); C1103(1.06); C1348(0.93); C1448(1.09)  LDD0776  [9]
 LDCM0460  CL68 HCT 116 C1066(0.72); C1103(1.09); C1348(0.89); C1448(1.47)  LDD0777  [9]
 LDCM0461  CL69 HCT 116 C1066(0.62); C1103(1.12); C1348(0.74); C1448(1.08)  LDD0778  [9]
 LDCM0462  CL7 HCT 116 C1066(1.09); C1103(1.06); C1348(1.31); C198(0.77)  LDD0779  [9]
 LDCM0463  CL70 HCT 116 C1066(0.65); C1103(1.05); C1348(0.69); C1448(0.93)  LDD0780  [9]
 LDCM0464  CL71 HCT 116 C1066(0.67); C1103(0.94); C1348(0.76); C1448(1.04)  LDD0781  [9]
 LDCM0465  CL72 HCT 116 C1066(0.65); C1103(0.92); C1348(0.64); C1448(1.15)  LDD0782  [9]
 LDCM0466  CL73 HCT 116 C1066(0.75); C1103(0.90); C1348(0.81); C1448(1.00)  LDD0783  [9]
 LDCM0467  CL74 HCT 116 C1066(0.68); C1103(0.94); C1348(0.69); C1448(1.28)  LDD0784  [9]
 LDCM0469  CL76 HCT 116 C1066(0.97); C1103(0.96); C1348(1.26); C1448(0.74)  LDD0786  [9]
 LDCM0470  CL77 HCT 116 C1066(0.89); C1103(0.73); C1348(1.07); C1448(1.08)  LDD0787  [9]
 LDCM0471  CL78 HCT 116 C1066(0.78); C1103(0.82); C1348(1.19); C1448(0.69)  LDD0788  [9]
 LDCM0472  CL79 HCT 116 C1066(1.02); C1103(0.78); C1348(1.42); C1448(1.16)  LDD0789  [9]
 LDCM0473  CL8 HCT 116 C1066(1.07); C1103(0.99); C1348(1.00); C198(0.52)  LDD0790  [9]
 LDCM0474  CL80 HCT 116 C1066(1.02); C1103(0.94); C1348(2.00); C1448(0.81)  LDD0791  [9]
 LDCM0475  CL81 HCT 116 C1066(0.81); C1103(0.87); C1348(1.17); C1448(0.82)  LDD0792  [9]
 LDCM0476  CL82 HCT 116 C1066(0.82); C1103(0.99); C1348(1.24); C1448(1.14)  LDD0793  [9]
 LDCM0477  CL83 HCT 116 C1066(0.88); C1103(0.90); C1348(1.47); C1448(0.93)  LDD0794  [9]
 LDCM0478  CL84 HCT 116 C1066(0.89); C1103(0.91); C1348(1.27); C1448(1.07)  LDD0795  [9]
 LDCM0479  CL85 HCT 116 C1066(0.90); C1103(0.94); C1348(1.17); C1448(0.64)  LDD0796  [9]
 LDCM0480  CL86 HCT 116 C1066(0.87); C1103(1.02); C1348(1.36); C1448(0.49)  LDD0797  [9]
 LDCM0481  CL87 HCT 116 C1066(0.81); C1103(0.90); C1348(1.21); C1448(0.81)  LDD0798  [9]
 LDCM0482  CL88 HCT 116 C1066(0.71); C1103(0.75); C1348(1.32); C1448(0.92)  LDD0799  [9]
 LDCM0483  CL89 HCT 116 C1066(0.89); C1103(0.78); C1348(1.40); C1448(1.04)  LDD0800  [9]
 LDCM0484  CL9 HCT 116 C1066(0.99); C1103(1.02); C1348(1.26); C198(0.63)  LDD0801  [9]
 LDCM0485  CL90 HCT 116 C1066(0.81); C1103(0.64); C1348(0.94); C1448(0.61)  LDD0802  [9]
 LDCM0486  CL91 HCT 116 C1066(1.28); C1103(1.24); C1348(1.10); C2088(0.88)  LDD0803  [9]
 LDCM0487  CL92 HCT 116 C1066(1.10); C1103(1.26); C1348(1.15); C2088(0.84)  LDD0804  [9]
 LDCM0488  CL93 HCT 116 C1066(1.19); C1103(1.52); C1348(1.03); C2088(0.91)  LDD0805  [9]
 LDCM0489  CL94 HCT 116 C1066(1.20); C1103(1.55); C1348(1.16); C2088(0.68)  LDD0806  [9]
 LDCM0490  CL95 HCT 116 C1066(1.12); C1103(1.21); C1348(0.89); C2088(0.75)  LDD0807  [9]
 LDCM0491  CL96 HCT 116 C1066(1.25); C1103(1.51); C1348(1.13); C2088(1.05)  LDD0808  [9]
 LDCM0492  CL97 HCT 116 C1066(1.15); C1103(1.50); C1348(0.96); C2088(0.99)  LDD0809  [9]
 LDCM0493  CL98 HCT 116 C1066(1.19); C1103(1.28); C1348(0.97); C2088(1.01)  LDD0810  [9]
 LDCM0494  CL99 HCT 116 C1066(1.36); C1103(1.43); C1348(1.06); C2088(1.15)  LDD0811  [9]
 LDCM0495  E2913 HEK-293T C626(1.24); C46(1.02); C2679(1.02); C1066(1.06)  LDD1698  [22]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C1906(1.51)  LDD1702  [6]
 LDCM0468  Fragment33 HCT 116 C1066(0.65); C1103(1.02); C1348(0.98); C1448(1.01)  LDD0785  [9]
 LDCM0427  Fragment51 HCT 116 C1066(0.66); C1103(0.86); C1348(1.23); C2154(0.83)  LDD0744  [9]
 LDCM0107  IAA HeLa C618(0.00); C1103(0.00); C2454(0.00); C626(0.00)  LDD0221  [16]
 LDCM0022  KB02 HCT 116 C46(1.93); C626(1.67); C1066(1.12)  LDD0080  [9]
 LDCM0023  KB03 HCT 116 C46(2.67); C626(1.45); C1066(1.07)  LDD0081  [9]
 LDCM0024  KB05 HCT 116 C46(4.50); C626(1.83); C1066(1.35)  LDD0082  [9]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C2679(1.28); C1066(0.91); C1991(1.18); C2154(1.04)  LDD2102  [6]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C728(1.62); C1448(0.47); C1906(0.68); C2660(1.16)  LDD2121  [6]
 LDCM0109  NEM HeLa N.A.  LDD0223  [16]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C728(1.37); C1448(0.57); C1906(0.58); C2679(0.96)  LDD2089  [6]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C2679(1.63); C1066(1.39); C1991(0.99); C2154(1.10)  LDD2090  [6]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C1448(2.22); C2679(0.94); C1066(1.08); C1013(2.46)  LDD2092  [6]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C728(1.20); C1448(1.94); C1906(0.94); C2660(1.15)  LDD2093  [6]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C1448(6.75); C1066(1.00); C1013(3.74)  LDD2094  [6]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C1448(0.31); C2454(0.60); C1066(3.77); C2552(0.20)  LDD2096  [6]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C728(1.38); C1448(0.99); C1906(0.79); C2660(0.64)  LDD2097  [6]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C2679(0.60); C1066(0.81); C1013(1.00)  LDD2098  [6]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C728(1.03); C1448(0.77); C1906(0.86); C2660(1.29)  LDD2099  [6]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C728(0.39); C1448(0.49); C2679(0.48); C1348(0.29)  LDD2100  [6]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C728(1.13); C1448(3.09); C1906(0.70); C2660(1.24)  LDD2101  [6]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C728(0.43); C1448(0.35); C2679(0.46); C1013(0.29)  LDD2104  [6]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C1448(1.62); C2679(1.44); C1066(1.10); C1991(1.45)  LDD2105  [6]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C728(0.56); C1448(0.47); C2679(0.47); C1348(0.20)  LDD2106  [6]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C1448(0.55); C1906(0.85); C2660(0.89); C2454(0.96)  LDD2107  [6]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C1906(0.50); C2679(0.69); C1348(0.17); C1066(0.75)  LDD2108  [6]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C728(0.67); C1906(0.55); C2660(0.65); C2454(0.82)  LDD2109  [6]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C728(0.37); C1448(0.11); C2679(0.54); C1348(0.42)  LDD2110  [6]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C728(0.94); C1448(0.60); C1906(0.87); C2660(1.10)  LDD2111  [6]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C728(0.64); C1448(0.35); C2679(0.52); C1066(0.66)  LDD2114  [6]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C728(0.55); C1448(0.90); C1906(0.46); C2679(0.52)  LDD2115  [6]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C1448(0.67); C1906(1.35); C2454(0.77); C1066(3.94)  LDD2116  [6]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C1448(0.63); C1906(1.63); C2454(0.87); C1066(3.53)  LDD2118  [6]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C728(1.38); C1448(2.42); C1906(2.21); C2454(1.12)  LDD2119  [6]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C728(1.48); C1448(1.30); C1906(0.89); C2454(0.62)  LDD2120  [6]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C728(1.34); C1448(0.49); C1906(1.78); C2660(0.48)  LDD2122  [6]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C728(0.87); C1448(0.50); C1906(0.76); C2660(0.80)  LDD2123  [6]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C728(0.12); C1448(0.52); C1906(1.26); C2660(0.54)  LDD2124  [6]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C728(0.57); C1448(0.62); C1906(0.75); C2660(0.97)  LDD2125  [6]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C1448(0.41); C1906(1.24); C2660(0.40); C2454(0.80)  LDD2126  [6]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C728(0.12); C1448(0.58); C1906(1.02); C2660(1.11)  LDD2127  [6]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C728(1.51); C1448(0.80); C1906(0.95); C2454(0.50)  LDD2128  [6]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C728(1.11); C1448(0.47); C1906(0.75); C2679(1.29)  LDD2129  [6]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C728(0.59); C1448(0.91); C1906(0.61); C2660(0.72)  LDD2133  [6]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C1448(0.82); C1348(0.35); C1066(0.43); C1991(0.81)  LDD2134  [6]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C728(0.91); C1448(0.36); C1906(0.75); C2660(1.19)  LDD2135  [6]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C728(0.84); C1448(0.70); C1906(1.00); C2660(1.24)  LDD2136  [6]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C728(0.95); C1448(0.58); C1906(0.89); C2660(0.88)  LDD2137  [6]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C1991(2.34); C2660(2.32); C1348(2.32); C2552(2.28)  LDD1700  [6]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C728(0.33); C1448(0.46); C1906(0.69); C2660(0.94)  LDD2140  [6]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C728(1.01); C1448(0.46); C2679(0.92); C1348(0.32)  LDD2141  [6]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C728(1.02); C1448(0.85); C1906(1.11); C2454(0.41)  LDD2143  [6]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C728(2.18); C1448(3.02); C1906(2.50); C2660(2.44)  LDD2144  [6]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C728(0.30); C1448(0.21); C1906(3.16); C2454(0.21)  LDD2145  [6]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C1448(0.72); C1906(0.79); C2660(0.90); C2454(0.92)  LDD2146  [6]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C728(2.81); C1448(3.63); C2454(1.43); C1066(2.15)  LDD2147  [6]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C1448(0.54); C1906(0.47); C2454(0.33); C1348(0.37)  LDD2148  [6]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C728(2.84); C1448(0.28); C1906(0.20); C1991(0.73)  LDD2149  [6]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C728(1.02); C1448(0.30); C1906(0.80); C2660(0.97)  LDD2150  [6]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C1448(0.45); C1906(1.04); C2454(0.34); C1066(4.13)  LDD2151  [6]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C728(2.12); C2679(1.65); C2154(2.13); C1013(4.92)  LDD2153  [6]
 LDCM0021  THZ1 HCT 116 C1348(1.44); C1066(1.26); C2679(1.21); C2154(1.02)  LDD2173  [9]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Tyrosine-protein kinase ABL1 (ABL1) Tyr protein kinase family P00519
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Myotilin (MYOT) Myotilin/palladin family Q9UBF9
Other
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Adapter molecule crk (CRK) CRK family P46108
Growth factor receptor-bound protein 2 (GRB2) GRB2/sem-5/DRK family P62993
Xin actin-binding repeat-containing protein 1 (XIRP1) Xin family Q702N8

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 2-Ethynylbenzaldehyde-Based, Lysine-Targeting Irreversible Covalent Inhibitors for Protein Kinases and Nonkinases. J Am Chem Soc. 2023 Feb 12. doi: 10.1021/jacs.2c11595. Online ahead of print.
Mass spectrometry data entry: PXD037665
3 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
4 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
5 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
6 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
7 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
8 Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. Nat Chem Biol. 2020 Feb;16(2):150-159. doi: 10.1038/s41589-019-0404-5. Epub 2019 Nov 25.
9 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
10 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
11 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
12 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
13 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
14 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
15 Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529022. doi: 10.1101/2023.02.17.529022.
Mass spectrometry data entry: PXD039931
16 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
17 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
18 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
19 Cell-based proteome profiling of potential dasatinib targets by use of affinity-based probes. J Am Chem Soc. 2012 Feb 15;134(6):3001-14. doi: 10.1021/ja208518u. Epub 2012 Feb 1.
20 Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probe. Chem Commun (Camb). 2011 Oct 28;47(40):11306-8. doi: 10.1039/c1cc14824a. Epub 2011 Sep 16.
21 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
22 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402