Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0539
Competitor Name
3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile
Synonyms
SCHEMBL13741621; 3-(4-isopropylpiperazin-1-yl)-3-oxopropanenitrile
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 195.26
Lipid-water partition coefficient (xlogp) 0.2
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C10H17N3O
IUPAC Name
3-oxo-3-(4-propan-2-ylpiperazin-1-yl)propanenitrile
Canonical SMILES
CC(C)N1CCN(CC1)C(=O)CC#N
InChI
InChI=1S/C10H17N3O/c1-9(2)12-5-7-13(8-6-12)10(14)3-4-11/h9H,3,5-8H2,1-2H3
InChIKey
FWGHZYZWVWYEDI-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
BTD
 Probe Info  		5 mM Human breast adenocarcinoma cell lysate (MDA-MB-231) [1]

Target(s) List of this Competitor

396 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
(E3-independent) E2 ubiquitin-conjugating enzyme (UBE2O) LDTP11601 0.62  LDD2132 
1,4-alpha-glucan-branching enzyme (GBE1) LDTP05419 0.62  LDD2132 
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (PLCB3) LDTP05327 0.35  LDD2132 
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) LDTP02984 0.63; 0.37  LDD2132 
116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2) LDTP06286 0.57; 0.51  LDD2132 
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (DECR1) LDTP06612 0.70  LDD2132 
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (GCAT) LDTP01268 0.59  LDD2132 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 0.32  LDD2132 
26S proteasome non-ATPase regulatory subunit 1 (PSMD1) LDTP10869 0.64; 0.66; 0.55 ...  LDD2132 
26S proteasome non-ATPase regulatory subunit 12 (PSMD12) LDTP00224 0.78  LDD2132 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 1.01  LDD2132 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 0.50; 0.54  LDD2132 
26S proteasome non-ATPase regulatory subunit 4 (PSMD4) LDTP04655 0.58  LDD2132 
26S proteasome non-ATPase regulatory subunit 5 (PSMD5) LDTP06532 1.03  LDD2132 
26S proteasome non-ATPase regulatory subunit 8 (PSMD8) LDTP04196 0.72  LDD2132 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 0.56  LDD2132 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 0.41  LDD2132 
26S proteasome regulatory subunit 6A (PSMC3) LDTP02933 0.58  LDD2132 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 0.44  LDD2132 
26S proteasome regulatory subunit 7 (PSMC2) LDTP03797 0.71; 0.58  LDD2132 
26S proteasome regulatory subunit 8 (PSMC5) LDTP04963 0.71  LDD2132 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 0.57  LDD2132 
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (HIBCH) LDTP07483 0.81  LDD2132 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 0.61  LDD2132 
4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) LDTP04232 0.55; 0.54  LDD2132 
5'-nucleotidase (NT5E) LDTP03120 0.47  LDD2132 
6-phosphogluconate dehydrogenase, decarboxylating (PGD) LDTP04499 0.54  LDD2132 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 0.58; 0.68; 0.81  LDD2132 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 0.42; 0.63; 0.41  LDD2132 
Aconitate hydratase, mitochondrial (ACO2) LDTP10982 0.49  LDD2132 
Actin, cytoplasmic 2 (ACTG1) LDTP05059 0.51  LDD2132 
Activated CDC42 kinase 1 (TNK2) LDTP05537 0.66  LDD2132 
Acyl-coenzyme A thioesterase 9, mitochondrial (ACOT9) LDTP16274 0.58  LDD2132 
Acyl-protein thioesterase 2 (LYPLA2) LDTP01573 0.64  LDD2132 
Adenosine 5'-monophosphoramidase HINT1 (HINT1) LDTP04306 0.28  LDD2132 
Adenosine kinase (ADK) LDTP04689 0.39  LDD2132 
Adenosylhomocysteinase (AHCY) LDTP03242 0.47  LDD2132 
Adenylosuccinate lyase (ADSL) LDTP03551 0.40  LDD2132 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 0.73; 0.36  LDD2132 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 0.49; 0.97  LDD2132 
Aldehyde dehydrogenase 1A1 (ALDH1A1) LDTP01767 0.42  LDD2132 
Aldo-keto reductase family 1 member B1 (AKR1B1) LDTP02765 1.02; 0.45; 0.56  LDD2132 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 0.51; 0.46  LDD2132 
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (MGAT1) LDTP03362 0.43  LDD2132 
Alpha-enolase (ENO1) LDTP02159 0.90; 1.01; 0.43  LDD2132 
Amidophosphoribosyltransferase (PPAT) LDTP05480 0.56  LDD2132 
Anaphase-promoting complex subunit 7 (ANAPC7) LDTP13409 0.44  LDD2132 
Antigen peptide transporter 2 (TAP2) LDTP05409 0.56  LDD2132 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 0.71  LDD2132 
Asparagine--tRNA ligase, cytoplasmic (NARS1) LDTP00866 0.64  LDD2132 
Aspartate aminotransferase, mitochondrial (GOT2) LDTP01783 0.36  LDD2132 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 0.72; 1.45  LDD2132 
Aspartyl aminopeptidase (DNPEP) LDTP13527 0.43; 0.65  LDD2132 
Aspartyl/asparaginyl beta-hydroxylase (ASPH) LDTP05652 0.50  LDD2132 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 0.92; 0.51  LDD2132 
ATP-citrate synthase (ACLY) LDTP04561 0.61; 0.45; 0.69  LDD2132 
ATP-dependent 6-phosphofructokinase, platelet type (PFKP) LDTP05314 0.47; 0.42  LDD2132 
ATP-dependent DNA helicase Q1 (RECQL) LDTP04083 0.57  LDD2132 
ATP-dependent DNA/RNA helicase DHX36 (DHX36) LDTP11841 0.72  LDD2132 
ATP-dependent RNA helicase A (DHX9) LDTP05550 0.50; 0.44; 0.35  LDD2132 
ATP-dependent RNA helicase DDX39A (DDX39A) LDTP00192 0.55; 1.07  LDD2132 
ATP-dependent RNA helicase DDX3Y (DDX3Y) LDTP00664 0.91; 0.57; 0.67 ...  LDD2132 
ATP-dependent RNA helicase DDX54 (DDX54) LDTP09428 0.72  LDD2132 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 0.68; 0.78  LDD2132 
ATP-dependent RNA helicase DHX30 (DHX30) LDTP07946 0.52  LDD2132 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 0.54  LDD2132 
Aurora kinase A (AURKA) LDTP00491 0.68  LDD2132 
Beta-1,4-galactosyltransferase 1 (B4GALT1) LDTP02777 0.93  LDD2132 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 0.53; 0.71  LDD2132 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 0.44  LDD2132 
Bleomycin hydrolase (BLMH) LDTP05992 0.53; 0.41  LDD2132 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 0.62; 0.43; 0.57  LDD2132 
Calcyclin-binding protein (CACYBP) LDTP12163 0.63  LDD2132 
Calpain-2 catalytic subunit (CAPN2) LDTP02911 0.80; 0.69; 0.40 ...  LDD2132 
cAMP-dependent protein kinase catalytic subunit alpha (PRKACA) LDTP02909 0.55  LDD2132 
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (CMTR1) LDTP08773 1.15; 0.49  LDD2132 
Carbonyl reductase [NADPH] 1 (CBR1) LDTP02831 0.87  LDD2132 
Carboxymethylenebutenolidase homolog (CMBL) LDTP10215 0.46  LDD2132 
Carboxypeptidase D (CPD) LDTP01372 0.87  LDD2132 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 0.65  LDD2132 
Casein kinase II subunit alpha' (CSNK2A2) LDTP03011 0.82  LDD2132 
Catalase (CAT) LDTP02001 0.59; 0.40  LDD2132 
Cathepsin B (CTSB) LDTP02223 0.48  LDD2132 
CCA tRNA nucleotidyltransferase 1, mitochondrial (TRNT1) LDTP10716 0.75  LDD2132 
Cell division control protein 42 homolog (CDC42) LDTP04886 0.47; 0.49  LDD2132 
Chromodomain-helicase-DNA-binding protein 1 (CHD1) LDTP00394 0.87  LDD2132 
Chromodomain-helicase-DNA-binding protein 4 (CHD4) LDTP06219 0.70  LDD2132 
Citrate synthase, mitochondrial (CS) LDTP01205 0.50  LDD2132 
Cleavage and polyadenylation specificity factor subunit 3 (CPSF3) LDTP13449 0.91  LDD2132 
COP9 signalosome complex subunit 5 (COPS5) LDTP09925 0.43  LDD2132 
CTP synthase 1 (CTPS1) LDTP02922 0.69; 0.58; 0.78  LDD2132 
Cullin-1 (CUL1) LDTP05946 0.57  LDD2132 
Cullin-2 (CUL2) LDTP05947 0.51  LDD2132 
Cullin-3 (CUL3) LDTP05948 0.55  LDD2132 
Cullin-associated NEDD8-dissociated protein 1 (CAND1) LDTP08296 0.81; 0.42; 0.62 ...  LDD2132 
Cyclic GMP-AMP synthase (CGAS) LDTP08974 0.47  LDD2132 
Cyclin-dependent kinase 4 (CDK4) LDTP02589 0.76  LDD2132 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 0.73  LDD2132 
Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) LDTP03610 0.52; 0.64  LDD2132 
Cytochrome b5 reductase 4 (CYB5R4) LDTP07942 0.63  LDD2132 
Cytoplasmic aconitate hydratase (ACO1) LDTP03110 0.46; 0.65  LDD2132 
Cytosol aminopeptidase (LAP3) LDTP03455 0.58  LDD2132 
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 0.65  LDD2132 
D-aspartate oxidase (DDO) LDTP10875 0.50  LDD2132 
D-dopachrome decarboxylase (DDT) LDTP03513 0.47  LDD2132 
Deoxycytidylate deaminase (DCTD) LDTP03643 0.42  LDD2132 
Deoxyribose-phosphate aldolase (DERA) LDTP13941 0.53  LDD2132 
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT) LDTP03669 0.68  LDD2132 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 0.76  LDD2132 
Diphosphomevalonate decarboxylase (MVD) LDTP04567 0.66  LDD2132 
DNA (cytosine-5)-methyltransferase 1 (DNMT1) LDTP03350 0.42  LDD2132 
DNA polymerase delta subunit 2 (POLD2) LDTP04223 0.73  LDD2132 
DNA polymerase epsilon catalytic subunit A (POLE) LDTP05532 0.55  LDD2132 
DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 0.63  LDD2132 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 0.50; 0.51  LDD2132 
DNA topoisomerase 1 (TOP1) LDTP02567 0.65; 0.86  LDD2132 
DNA topoisomerase 2-alpha (TOP2A) LDTP02568 0.50  LDD2132 
DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 0.66; 0.42; 0.63 ...  LDD2132 
DNA-directed RNA polymerase I subunit RPA1 (POLR1A) LDTP01636 1.10  LDD2132 
DNA-directed RNA polymerase, mitochondrial (POLRMT) LDTP00267 0.66  LDD2132 
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (POLR2H) LDTP04507 0.61  LDD2132 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 0.45  LDD2132 
Double-stranded RNA-specific adenosine deaminase (ADAR) LDTP04690 0.54  LDD2132 
Dual specificity protein phosphatase 3 (DUSP3) LDTP04415 0.85  LDD2132 
Dynamin-1-like protein (DNM1L) LDTP00273 0.80; 0.39  LDD2132 
Dynamin-2 (DNM2) LDTP04374 0.95  LDD2132 
E3 SUMO-protein ligase RanBP2 (RANBP2) LDTP04310 0.44; 0.65; 0.50 ...  LDD2132 
E3 ubiquitin-protein ligase ARIH1 (ARIH1) LDTP14079 0.67  LDD2132 
E3 ubiquitin-protein ligase HUWE1 (HUWE1) LDTP08135 1.04; 0.59  LDD2132 
E3 ubiquitin-protein ligase RBX1 (RBX1) LDTP05019 0.78  LDD2132 
E3 ubiquitin-protein ligase RNF114 (RNF114) LDTP14083 0.41  LDD2132 
E3 ubiquitin-protein ligase SMURF2 (SMURF2) LDTP12138 0.51  LDD2132 
E3 ubiquitin-protein ligase TRIM33 (TRIM33) LDTP13702 0.50  LDD2132 
E3 ubiquitin-protein ligase UBR4 (UBR4) LDTP07118 0.82; 0.75  LDD2132 
E3 ubiquitin-protein ligase UHRF1 (UHRF1) LDTP10845 0.89  LDD2132 
E3 ubiquitin/ISG15 ligase TRIM25 (TRIM25) LDTP06098 0.75  LDD2132 
Egl nine homolog 1 (EGLN1) LDTP11649 0.70  LDD2132 
Electron transfer flavoprotein subunit alpha, mitochondrial (ETFA) LDTP02694 1.35  LDD2132 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 0.66  LDD2132 
Elongation factor 1-alpha 2 (EEF1A2) LDTP05460 0.43  LDD2132 
Elongation factor 2 (EEF2) LDTP02672 0.68; 0.63; 0.68 ...  LDD2132 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 0.57; 0.81  LDD2132 
Ephrin type-A receptor 2 (EPHA2) LDTP03474 0.59  LDD2132 
Ester hydrolase C11orf54 (C11orf54) LDTP11738 0.73  LDD2132 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 0.52  LDD2132 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 0.79; 0.72; 0.64 ...  LDD2132 
Eukaryotic translation initiation factor 3 subunit F (EIF3F) LDTP00246 0.52  LDD2132 
Eukaryotic translation initiation factor 5B (EIF5B) LDTP01063 1.05; 0.74; 0.66  LDD2132 
Exosome complex component MTR3 (EXOSC6) LDTP07054 0.52  LDD2132 
Exosome complex component RRP41 (EXOSC4) LDTP12346 0.59  LDD2132 
F-box/LRR-repeat protein 18 (FBXL18) LDTP15784 1.37  LDD2132 
Fatty acid synthase (FASN) LDTP04243 0.88; 0.74; 0.45 ...  LDD2132 
Galactokinase (GALK1) LDTP04424 0.85  LDD2132 
GDP-fucose protein O-fucosyltransferase 1 (POFUT1) LDTP11905 0.68; 0.71  LDD2132 
Geranylgeranyl transferase type-2 subunit alpha (RABGGTA) LDTP09845 0.58  LDD2132 
Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 0.59  LDD2132 
Glucose-6-phosphate isomerase (GPI) LDTP02162 0.41  LDD2132 
Glucoside xylosyltransferase 1 (GXYLT1) LDTP14932 0.45  LDD2132 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) LDTP05481 0.43  LDD2132 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (GFPT2) LDTP01423 0.55  LDD2132 
Glutamine--tRNA ligase (QARS1) LDTP04135 0.71  LDD2132 
Glutaredoxin-3 (GLRX3) LDTP01374 0.47  LDD2132 
Glutathione S-transferase Mu 3 (GSTM3) LDTP03103 1.15  LDD2132 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 0.86  LDD2132 
Glutathione S-transferase P (GSTP1) LDTP02333 0.66; 0.50; 0.66  LDD2132 
Glutathione synthetase (GSS) LDTP04200 0.45; 0.39  LDD2132 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 0.39; 0.49; 0.99  LDD2132 
Glycine--tRNA ligase (GARS1) LDTP03946 0.59  LDD2132 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 0.50; 0.54; 0.60 ...  LDD2132 
Glycylpeptide N-tetradecanoyltransferase 1 (NMT1) LDTP03537 0.44  LDD2132 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 0.43  LDD2132 
GMP reductase 2 (GMPR2) LDTP13080 0.59  LDD2132 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 0.53  LDD2132 
GTP-binding nuclear protein Ran (RAN) LDTP05007 0.74; 0.73  LDD2132 
Guanine nucleotide-binding protein-like 3 (GNL3) LDTP11297 0.63  LDD2132 
Guanine nucleotide-binding protein-like 3-like protein (GNL3L) LDTP12687 0.54  LDD2132 
H/ACA ribonucleoprotein complex subunit DKC1 (DKC1) LDTP01061 0.37  LDD2132 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 0.51  LDD2132 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 0.39  LDD2132 
Heme oxygenase 2 (HMOX2) LDTP03540 0.60  LDD2132 
Hexokinase-1 (HK1) LDTP02991 0.68; 0.46  LDD2132 
Hexokinase-2 (HK2) LDTP04531 0.65; 0.59; 0.67  LDD2132 
Histidine--tRNA ligase, cytoplasmic (HARS1) LDTP02602 0.30  LDD2132 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 0.55; 0.57  LDD2132 
Histone deacetylase 1 (HDAC1) LDTP05918 0.49  LDD2132 
Histone-lysine N-trimethyltransferase SMYD5 (SMYD5) LDTP07388 0.58  LDD2132 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 0.43  LDD2132 
Hydroxysteroid dehydrogenase-like protein 2 (HSDL2) LDTP07762 0.81  LDD2132 
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) LDTP01782 0.59; 0.47  LDD2132 
Immunity-related GTPase family Q protein (IRGQ) LDTP19838 0.70  LDD2132 
Inorganic pyrophosphatase (PPA1) LDTP14854 0.59  LDD2132 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 0.58  LDD2132 
Inositol hexakisphosphate kinase 1 (IP6K1) LDTP09792 1.06  LDD2132 
Inositol monophosphatase 1 (IMPA1) LDTP03470 0.70  LDD2132 
Insulin-degrading enzyme (IDE) LDTP02743 0.50  LDD2132 
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) LDTP11700 0.54; 0.43  LDD2132 
Integrin-linked protein kinase (ILK) LDTP05859 0.56  LDD2132 
Isoamyl acetate-hydrolyzing esterase 1 homolog (IAH1) LDTP17082 0.43  LDD2132 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 1.12  LDD2132 
Isoleucine--tRNA ligase, cytoplasmic (IARS1) LDTP03947 0.41  LDD2132 
Kinesin-like protein KIF20A (KIF20A) LDTP01535 0.56  LDD2132 
Kinesin-like protein KIF2C (KIF2C) LDTP10935 0.56  LDD2132 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 0.41  LDD2132 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 0.56; 0.79  LDD2132 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 0.56  LDD2132 
Lon protease homolog, mitochondrial (LONP1) LDTP03817 0.41; 0.72  LDD2132 
Long-chain-fatty-acid--CoA ligase 4 (ACSL4) LDTP00982 0.84  LDD2132 
Low molecular weight phosphotyrosine protein phosphatase (ACP1) LDTP03289 0.50  LDD2132 
Lymphokine-activated killer T-cell-originated protein kinase (PBK) LDTP10500 0.66  LDD2132 
Lysine-specific histone demethylase 1A (KDM1A) LDTP00957 0.98  LDD2132 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 0.33; 0.39  LDD2132 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 0.30  LDD2132 
MAP kinase-activated protein kinase 3 (MAPKAPK3) LDTP06589 0.57  LDD2132 
Microsomal glutathione S-transferase 1 (MGST1) LDTP02506 0.63  LDD2132 
Minor histocompatibility antigen H13 (HM13) LDTP09396 0.43  LDD2132 
Mitochondrial import inner membrane translocase subunit TIM50 (TIMM50) LDTP06810 0.56  LDD2132 
Mitochondrial Rho GTPase 2 (RHOT2) LDTP08596 0.60  LDD2132 
Mitogen-activated protein kinase 14 (MAPK14) LDTP06547 0.69  LDD2132 
Mitogen-activated protein kinase 3 (MAPK3) LDTP03387 0.50; 0.95  LDD2132 
Molybdopterin synthase catalytic subunit (MOCS2) LDTP01747 0.35  LDD2132 
Multifunctional protein CAD (CAD) LDTP03401 0.70; 0.64; 0.60 ...  LDD2132 
Myosin-9 (MYH9) LDTP03764 0.62; 0.76; 0.67  LDD2132 
N-acetyl-D-glucosamine kinase (NAGK) LDTP13372 2.25  LDD2132 
N-alpha-acetyltransferase 10 (NAA10) LDTP03938 0.62  LDD2132 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 0.60  LDD2132 
N-alpha-acetyltransferase 25, NatB auxiliary subunit (NAA25) LDTP06262 0.56  LDD2132 
N-lysine methyltransferase SMYD2 (SMYD2) LDTP12509 1.17  LDD2132 
N6-adenosine-methyltransferase catalytic subunit (METTL3) LDTP08214 0.66  LDD2132 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 0.56  LDD2132 
NEDD4-like E3 ubiquitin-protein ligase WWP1 (WWP1) LDTP11719 0.35  LDD2132 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 0.48  LDD2132 
Neutral alpha-glucosidase AB (GANAB) LDTP06192 0.47; 0.62  LDD2132 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 1.10  LDD2132 
Nuclear pore complex protein Nup98-Nup96 (NUP98) LDTP04547 0.51  LDD2132 
Nucleolar GTP-binding protein 2 (GNL2) LDTP05987 0.60  LDD2132 
Nucleolar RNA helicase 2 (DDX21) LDTP12469 0.66; 1.17  LDD2132 
Obg-like ATPase 1 (OLA1) LDTP12610 0.74; 0.74  LDD2132 
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (CPOX) LDTP03813 0.39  LDD2132 
PAN2-PAN3 deadenylation complex subunit PAN3 (PAN3) LDTP06935 0.53  LDD2132 
Parkinson disease protein 7 (PARK7) LDTP10878 0.31  LDD2132 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 0.38; 0.96; 0.33 ...  LDD2132 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 0.45  LDD2132 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 0.58; 0.49; 0.54  LDD2132 
Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8) LDTP06104 0.54; 0.44  LDD2132 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) LDTP05912 0.68  LDD2132 
Peptidyl-prolyl cis-trans isomerase-like 1 (PPIL1) LDTP13976 0.53  LDD2132 
Peptidyl-tRNA hydrolase 2, mitochondrial (PTRH2) LDTP13989 0.55  LDD2132 
Peroxiredoxin-1 (PRDX1) LDTP05503 0.54  LDD2132 
Peroxiredoxin-4 (PRDX4) LDTP05773 0.59  LDD2132 
Peroxiredoxin-6 (PRDX6) LDTP03510 0.58; 0.92  LDD2132 
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (INPPL1) LDTP00617 1.64  LDD2132 
Phosphoacetylglucosamine mutase (PGM3) LDTP01584 0.46  LDD2132 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 0.57; 0.48  LDD2132 
Phosphoglycerate mutase 1 (PGAM1) LDTP02963 0.66  LDD2132 
Phospholipase A-2-activating protein (PLAA) LDTP13814 0.74; 0.52  LDD2132 
Phosphopentomutase (PGM2) LDTP10326 0.43  LDD2132 
Phosphoribosylformylglycinamidine synthase (PFAS) LDTP00527 0.56; 0.55  LDD2132 
Platelet-activating factor acetylhydrolase IB subunit alpha1 (PAFAH1B3) LDTP06315 0.73  LDD2132 
Platelet-activating factor acetylhydrolase IB subunit alpha2 (PAFAH1B2) LDTP05078 0.56  LDD2132 
Poly [ADP-ribose] polymerase 1 (PARP1) LDTP02375 0.54; 0.51  LDD2132 
Pre-mRNA-processing factor 19 (PRPF19) LDTP13623 0.72  LDD2132 
Presequence protease, mitochondrial (PITRM1) LDTP07003 0.54  LDD2132 
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (NOP2) LDTP04084 0.56  LDD2132 
Probable ATP-dependent RNA helicase DDX17 (DDX17) LDTP09899 0.69  LDD2132 
Probable ATP-dependent RNA helicase DDX23 (DDX23) LDTP11248 0.43  LDD2132 
Probable ATP-dependent RNA helicase DDX5 (DDX5) LDTP02924 0.43  LDD2132 
Probable ATP-dependent RNA helicase DDX6 (DDX6) LDTP03348 0.69  LDD2132 
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X) LDTP09961 0.63; 0.92  LDD2132 
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2) LDTP00285 0.90  LDD2132 
Proliferation-associated protein 2G4 (PA2G4) LDTP13750 0.61; 0.65; 0.98  LDD2132 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 0.72  LDD2132 
Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB) LDTP02096 0.63  LDD2132 
Prostaglandin E synthase 3 (PTGES3) LDTP06338 0.55  LDD2132 
Proteasome subunit alpha type-3 (PSMA3) LDTP03332 0.40  LDD2132 
Proteasome subunit alpha type-4 (PSMA4) LDTP03333 0.33  LDD2132 
Proteasome subunit alpha type-5 (PSMA5) LDTP03413 0.38  LDD2132 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 0.37  LDD2132 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 0.47  LDD2132 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 0.48; 0.54  LDD2132 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 0.57; 0.60  LDD2132 
Proteasome subunit beta type-3 (PSMB3) LDTP04284 0.68  LDD2132 
Proteasome subunit beta type-7 (PSMB7) LDTP10862 0.24  LDD2132 
Protein arginine N-methyltransferase 1 (PRMT1) LDTP10997 0.68  LDD2132 
Protein disulfide-isomerase (P4HB) LDTP02188 0.36  LDD2132 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 0.40; 0.71  LDD2132 
Protein kinase C theta type (PRKCQ) LDTP05433 0.61  LDD2132 
Protein phosphatase 1G (PPM1G) LDTP00616 0.46; 0.64  LDD2132 
Protein phosphatase methylesterase 1 (PPME1) LDTP14092 0.75; 0.54  LDD2132 
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 0.52; 0.66; 0.69 ...  LDD2132 
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT1) LDTP03152 0.51  LDD2132 
Proto-oncogene tyrosine-protein kinase Src (SRC) LDTP02638 0.48  LDD2132 
Purine nucleoside phosphorylase (PNP) LDTP01781 0.45  LDD2132 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 0.35  LDD2132 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 0.52  LDD2132 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 0.59  LDD2132 
Pyruvate kinase PKM (PKM) LDTP02733 0.83; 0.51; 0.45 ...  LDD2132 
Quinone oxidoreductase (CRYZ) LDTP05551 0.45  LDD2132 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 0.39  LDD2132 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 0.58; 0.59  LDD2132 
Ras-related C3 botulinum toxin substrate 2 (RAC2) LDTP02768 0.55; 0.58  LDD2132 
Ras-related protein Rab-13 (RAB13) LDTP04401 0.59  LDD2132 
Ras-related protein Rab-14 (RAB14) LDTP04901 0.52  LDD2132 
Ras-related protein Rab-1A (RAB1A) LDTP05006 0.51  LDD2132 
Ras-related protein Rab-34 (RAB34) LDTP11535 0.73  LDD2132 
Ras-related protein Rab-4A (RAB4A) LDTP03049 0.68  LDD2132 
Ras-related protein Rab-8A (RAB8A) LDTP04888 0.80; 0.95  LDD2132 
Ras-related protein Rap-1b (RAP1B) LDTP04910 0.75; 0.61  LDD2132 
Replication factor C subunit 2 (RFC2) LDTP03726 0.66  LDD2132 
Rho family-interacting cell polarization regulator 1 (RIPOR1) LDTP07819 0.61  LDD2132 
Rho-associated protein kinase 2 (ROCK2) LDTP01127 0.67; 1.07  LDD2132 
Ribonucleoside-diphosphate reductase large subunit (RRM1) LDTP03259 0.52  LDD2132 
Ribose-phosphate pyrophosphokinase 1 (PRPS1) LDTP04882 0.48; 0.61  LDD2132 
Ribose-phosphate pyrophosphokinase 3 (PRPS1L1) LDTP03097 0.88  LDD2132 
Ribosomal RNA small subunit methyltransferase NEP1 (EMG1) LDTP09951 0.68  LDD2132 
RNA cytidine acetyltransferase (NAT10) LDTP11690 0.94; 0.49  LDD2132 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 0.87; 0.59; 0.50  LDD2132 
RNA helicase aquarius (AQR) LDTP00946 0.70  LDD2132 
RNA-splicing ligase RtcB homolog (RTCB) LDTP13992 0.50; 0.54  LDD2132 
RuvB-like 1 (RUVBL1) LDTP13816 0.50  LDD2132 
RuvB-like 2 (RUVBL2) LDTP13787 0.49  LDD2132 
S-adenosylmethionine synthase isoform type-2 (MAT2A) LDTP03577 0.40  LDD2132 
S-formylglutathione hydrolase (ESD) LDTP02521 0.42  LDD2132 
S-phase kinase-associated protein 1 (SKP1) LDTP05052 0.62; 0.41  LDD2132 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 0.84; 0.55; 0.68  LDD2132 
Secernin-1 (SCRN1) LDTP05640 0.69; 0.31  LDD2132 
Septin-10 (SEPTIN10) LDTP12987 0.68  LDD2132 
Serine beta-lactamase-like protein LACTB, mitochondrial (LACTB) LDTP05183 0.61  LDD2132 
Serine hydrolase RBBP9 (RBBP9) LDTP01338 0.50  LDD2132 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 1.16; 0.54  LDD2132 
Serine palmitoyltransferase 2 (SPTLC2) LDTP00598 0.58  LDD2132 
Serine/threonine-protein kinase A-Raf (ARAF) LDTP02493 0.56  LDD2132 
Serine/threonine-protein kinase Chk1 (CHEK1) LDTP00422 0.55  LDD2132 
Serine/threonine-protein kinase PAK 3 (PAK3) LDTP01351 0.43  LDD2132 
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D) LDTP06199 0.43  LDD2132 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 0.85  LDD2132 
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) LDTP04960 0.52  LDD2132 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 0.57; 0.64; 0.58  LDD2132 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 0.84; 0.71; 0.62 ...  LDD2132 
Spermine synthase (SMS) LDTP04530 0.55; 0.26  LDD2132 
Sphingosine-1-phosphate phosphatase 1 (SGPP1) LDTP11361 0.54  LDD2132 
Spliceosome RNA helicase DDX39B (DDX39B) LDTP05991 0.49; 0.63  LDD2132 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 0.82; 0.62  LDD2132 
Sterol O-acyltransferase 1 (SOAT1) LDTP03769 0.92  LDD2132 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 0.88  LDD2132 
Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA) LDTP03572 0.47; 0.59  LDD2132 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 0.62; 0.62; 0.56  LDD2132 
SUMO-activating enzyme subunit 2 (UBA2) LDTP13156 0.66  LDD2132 
Superoxide dismutase [Cu-Zn] (SOD1) LDTP01776 0.41  LDD2132 
Thimet oligopeptidase (THOP1) LDTP04542 0.48; 0.54  LDD2132 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 0.44  LDD2132 
Thioredoxin reductase 1, cytoplasmic (TXNRD1) LDTP06658 0.29  LDD2132 
Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) LDTP03515 0.53  LDD2132 
Thymidine kinase, cytosolic (TK1) LDTP02022 0.56  LDD2132 
Transaldolase (TALDO1) LDTP03847 0.74  LDD2132 
Transcription activator BRG1 (SMARCA4) LDTP04422 0.83  LDD2132 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 0.49; 0.77  LDD2132 
Transforming protein RhoA (RHOA) LDTP04927 0.66  LDD2132 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 0.45; 0.36; 0.40  LDD2132 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 0.46; 0.49; 1.18  LDD2132 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 0.98; 0.47; 0.68  LDD2132 
Triosephosphate isomerase (TPI1) LDTP04851 0.43; 0.63; 0.41  LDD2132 
Tripartite motif-containing protein 26 (TRIM26) LDTP05686 1.03  LDD2132 
Tripeptidyl-peptidase 2 (TPP2) LDTP03469 0.65  LDD2132 
TRMT1-like protein (TRMT1L) LDTP15236 0.49  LDD2132 
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (TRMT61A) LDTP10320 0.49  LDD2132 
tRNA (guanine(6)-N2)-methyltransferase THUMP3 (THUMPD3) LDTP11266 0.49  LDD2132 
Tubulin alpha-1C chain (TUBA1C) LDTP11074 0.82; 0.61  LDD2132 
Tubulin alpha-4A chain (TUBA4A) LDTP05075 0.58  LDD2132 
Tyrosine--tRNA ligase, cytoplasmic (YARS1) LDTP04617 0.64  LDD2132 
Tyrosine-protein kinase Yes (YES1) LDTP02231 0.56  LDD2132 
Tyrosine-protein phosphatase non-receptor type 1 (PTPN1) LDTP02935 0.50; 0.69  LDD2132 
Tyrosine-protein phosphatase non-receptor type 2 (PTPN2) LDTP02917 0.54  LDD2132 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 0.63  LDD2132 
Ubiquitin carboxyl-terminal hydrolase 14 (USP14) LDTP04618 0.84  LDD2132 
Ubiquitin carboxyl-terminal hydrolase 15 (USP15) LDTP14051 0.41  LDD2132 
Ubiquitin carboxyl-terminal hydrolase 39 (USP39) LDTP06903 1.11  LDD2132 
Ubiquitin carboxyl-terminal hydrolase 5 (USP5) LDTP04074 0.68; 1.29  LDD2132 
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCHL3) LDTP02783 0.52  LDD2132 
Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 0.75  LDD2132 
Ubiquitin-conjugating enzyme E2 L3 (UBE2L3) LDTP05070 0.58  LDD2132 
Ubiquitin-conjugating enzyme E2 variant 1 (UBE2V1) LDTP05853 0.46  LDD2132 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 0.59; 0.48  LDD2132 
Ubiquitin-like modifier-activating enzyme 6 (UBA6) LDTP00013 0.69  LDD2132 
Ubiquitin-protein ligase E3A (UBE3A) LDTP05446 0.39  LDD2132 
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) LDTP11867 0.54  LDD2132 
Unconventional myosin-Ie (MYO1E) LDTP05708 0.47  LDD2132 
Urokinase-type plasminogen activator (PLAU) LDTP01799 0.68  LDD2132 
UTP--glucose-1-phosphate uridylyltransferase (UGP2) LDTP06649 0.55  LDD2132 
Utrophin (UTRN) LDTP04116 0.56  LDD2132 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 0.95  LDD2132 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 0.38  LDD2132 
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) LDTP04289 0.70  LDD2132 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 0.57  LDD2132 
Vesicle-fusing ATPase (NSF) LDTP04096 0.41  LDD2132 
WD repeat-containing protein 82 (WDR82) LDTP07715 0.79  LDD2132 
X-ray repair cross-complementing protein 6 (XRCC6) LDTP02640 0.41  LDD2132 
------------------------------------------------------------------------------------
⏷ Show the Full List of 396 Enzyme
124 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein gamma (YWHAG) LDTP04953 0.66  LDD2132 
14-3-3 protein theta (YWHAQ) LDTP03385 0.80; 0.70  LDD2132 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 0.56  LDD2132 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 0.91  LDD2132 
Annexin A6 (ANXA6) LDTP02247 0.52; 0.54  LDD2132 
Anoctamin-6 (ANO6) LDTP06855 0.56  LDD2132 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 0.40; 0.64; 1.05 ...  LDD2132 
AP-2 complex subunit alpha-1 (AP2A1) LDTP01673 0.42; 0.38  LDD2132 
AP-2 complex subunit alpha-2 (AP2A2) LDTP01477 0.50  LDD2132 
AP-2 complex subunit beta (AP2B1) LDTP05038 0.98; 0.35; 0.63 ...  LDD2132 
AP-3 complex subunit delta-1 (AP3D1) LDTP00383 1.09  LDD2132 
Apoptosis regulator BAX (BAX) LDTP05528 0.82  LDD2132 
Apoptotic chromatin condensation inducer in the nucleus (ACIN1) LDTP13490 0.58  LDD2132 
Apoptotic protease-activating factor 1 (APAF1) LDTP00411 0.64  LDD2132 
ATP synthase subunit gamma, mitochondrial (ATP5F1C) LDTP03810 0.39  LDD2132 
ATP-binding cassette sub-family F member 2 (ABCF2) LDTP18526 0.54; 0.61; 0.89  LDD2132 
Calnexin (CANX) LDTP03405 0.52  LDD2132 
Calreticulin (CALR) LDTP03402 0.63  LDD2132 
Cation-dependent mannose-6-phosphate receptor (M6PR) LDTP03061 0.61  LDD2132 
CD151 antigen (CD151) LDTP04187 0.59; 0.39; 0.37  LDD2132 
CD44 antigen (CD44) LDTP02823 0.55  LDD2132 
Cellular tumor antigen p53 (TP53) LDTP02048 2.24  LDD2132 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 0.78; 0.87; 0.47  LDD2132 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 0.76  LDD2132 
Clathrin heavy chain 1 (CLTC) LDTP05252 0.60; 0.58; 0.74 ...  LDD2132 
Clathrin light chain A (CLTA) LDTP02352 0.37  LDD2132 
Claudin domain-containing protein 1 (CLDND1) LDTP16136 0.42  LDD2132 
Copine-1 (CPNE1) LDTP10989 0.52  LDD2132 
Copine-3 (CPNE3) LDTP01133 0.58; 0.44  LDD2132 
Cytochrome c oxidase subunit 5B, mitochondrial (COX5B) LDTP02504 0.50  LDD2132 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) LDTP02057 0.49  LDD2132 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) LDTP02058 0.86  LDD2132 
Dysferlin (DYSF) LDTP01355 0.50  LDD2132 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 1.40  LDD2132 
Endoplasmic reticulum junction formation protein lunapark (LNPK) LDTP11609 0.59  LDD2132 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 0.44  LDD2132 
Eukaryotic translation initiation factor 5A-1 (EIF5A) LDTP05056 0.48  LDD2132 
Eukaryotic translation initiation factor 5A-1-like (EIF5AL1) LDTP17347 0.49  LDD2132 
Exocyst complex component 1 (EXOC1) LDTP12661 0.88  LDD2132 
Exportin-1 (XPO1) LDTP00501 0.51; 0.47  LDD2132 
Exportin-2 (CSE1L) LDTP04662 0.78; 0.62; 0.56 ...  LDD2132 
Exportin-5 (XPO5) LDTP12142 0.49  LDD2132 
Fatty acid-binding protein 5 (FABP5) LDTP05292 0.65; 0.74; 0.40  LDD2132 
Filamin-A (FLNA) LDTP03107 0.38; 0.79; 0.56 ...  LDD2132 
Filamin-B (FLNB) LDTP01197 0.59; 0.66; 0.52 ...  LDD2132 
Filamin-C (FLNC) LDTP06103 0.80; 0.31; 0.76 ...  LDD2132 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1) LDTP05017 0.46  LDD2132 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2) LDTP05020 0.39  LDD2132 
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (GNAS) LDTP05040 0.66  LDD2132 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 0.73  LDD2132 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 0.46  LDD2132 
Histone deacetylase complex subunit SAP18 (SAP18) LDTP00270 0.44  LDD2132 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 0.50  LDD2132 
Importin subunit alpha-7 (KPNA6) LDTP01031 0.71  LDD2132 
Importin subunit beta-1 (KPNB1) LDTP06242 0.57  LDD2132 
Importin-4 (IPO4) LDTP09515 0.66; 0.74  LDD2132 
Importin-5 (IPO5) LDTP00266 0.55; 0.50; 0.90 ...  LDD2132 
Importin-7 (IPO7) LDTP01574 0.62; 0.63  LDD2132 
Importin-9 (IPO9) LDTP10663 0.57  LDD2132 
Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) LDTP06153 0.61  LDD2132 
Integrin alpha-6 (ITGA6) LDTP03211 0.67  LDD2132 
Integrin beta-1 (ITGB1) LDTP02122 0.46  LDD2132 
Kinesin-1 heavy chain (KIF5B) LDTP03664 0.61; 0.59; 0.72  LDD2132 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 0.70; 0.40  LDD2132 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 0.75  LDD2132 
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1) LDTP13698 0.83; 0.39; 1.00 ...  LDD2132 
Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) LDTP05384 0.78  LDD2132 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 1.11  LDD2132 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 0.74  LDD2132 
Myoferlin (MYOF) LDTP12916 0.40; 0.42; 0.54  LDD2132 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 0.62  LDD2132 
Nuclear cap-binding protein subunit 1 (NCBP1) LDTP05591 0.75  LDD2132 
Nuclear pore complex protein Nup107 (NUP107) LDTP04800 0.56  LDD2132 
Nuclear pore complex protein Nup153 (NUP153) LDTP04309 0.54; 0.59  LDD2132 
Nuclear pore complex protein Nup160 (NUP160) LDTP05642 0.54  LDD2132 
Nuclear pore complex protein Nup205 (NUP205) LDTP09825 0.42  LDD2132 
Nuclear pore complex protein Nup214 (NUP214) LDTP03777 0.62  LDD2132 
Nuclear pore complex protein Nup50 (NUP50) LDTP13498 0.43  LDD2132 
Nuclear pore complex protein Nup85 (NUP85) LDTP11310 0.63; 0.79  LDD2132 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 0.87  LDD2132 
Nucleoporin NDC1 (NDC1) LDTP11213 0.49  LDD2132 
Nucleoporin Nup43 (NUP43) LDTP09202 0.52  LDD2132 
Nucleoporin p58/p45 (NUP58) LDTP11293 0.70  LDD2132 
Nucleoprotein TPR (TPR) LDTP02612 0.35  LDD2132 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 0.89  LDD2132 
Phosphorylated adapter RNA export protein (PHAX) LDTP12043 0.52  LDD2132 
Podocalyxin (PODXL) LDTP00321 0.72; 0.61  LDD2132 
Protein S100-A10 (S100A10) LDTP04885 0.58  LDD2132 
Protein SEC13 homolog (SEC13) LDTP04707 0.52  LDD2132 
Protein SON (SON) LDTP02959 0.73  LDD2132 
Protein transport protein Sec31A (SEC31A) LDTP01478 0.61  LDD2132 
Protein transport protein Sec61 subunit alpha isoform 1 (SEC61A1) LDTP04932 0.70  LDD2132 
Ran GTPase-activating protein 1 (RANGAP1) LDTP04082 0.44; 0.53  LDD2132 
Sialin (SLC17A5) LDTP12492 0.31  LDD2132 
Sideroflexin-4 (SFXN4) LDTP07531 0.73  LDD2132 
Signal recognition particle 9 kDa protein (SRP9) LDTP04259 0.71  LDD2132 
Signal recognition particle subunit SRP68 (SRP68) LDTP13262 0.72  LDD2132 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 1.02; 0.49; 0.47 ...  LDD2132 
Sodium-dependent phosphate transporter 1 (SLC20A1) LDTP09581 0.61  LDD2132 
Sodium/potassium-transporting ATPase subunit beta-1 (ATP1B1) LDTP02068 0.36  LDD2132 
Solute carrier family 25 member 3 (SLC25A3) LDTP05238 0.65  LDD2132 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 0.62  LDD2132 
Sorting nexin-12 (SNX12) LDTP13634 0.41  LDD2132 
Sorting nexin-5 (SNX5) LDTP14174 0.63  LDD2132 
Spectrin beta chain, non-erythrocytic 1 (SPTBN1) LDTP05273 0.34; 0.38  LDD2132 
T-complex protein 1 subunit delta (CCT4) LDTP04391 0.45; 0.87; 0.50 ...  LDD2132 
Talin-1 (TLN1) LDTP14031 0.44; 1.16; 0.49 ...  LDD2132 
TBC1 domain family member 4 (TBC1D4) LDTP00958 0.47  LDD2132 
THO complex subunit 1 (THOC1) LDTP10317 0.40  LDD2132 
THO complex subunit 2 (THOC2) LDTP09279 0.44  LDD2132 
Transferrin receptor protein 1 (TFRC) LDTP01969 0.38  LDD2132 
Translocation protein SEC63 homolog (SEC63) LDTP13243 0.59; 0.30  LDD2132 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 0.59  LDD2132 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 0.82  LDD2132 
Transmembrane protein 176B (TMEM176B) LDTP06805 0.38  LDD2132 
Transportin-1 (TNPO1) LDTP09949 0.34  LDD2132 
Transportin-3 (TNPO3) LDTP14133 0.66  LDD2132 
Unconventional myosin-Ic (MYO1C) LDTP00196 0.57; 0.52  LDD2132 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 0.65; 0.47; 0.55  LDD2132 
Vesicle-associated membrane protein-associated protein A (VAPA) LDTP12966 0.52  LDD2132 
Vesicle-associated membrane protein-associated protein B/C (VAPB) LDTP01556 0.91  LDD2132 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 0.48  LDD2132 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 0.62  LDD2132 
Zinc transporter ZIP6 (SLC39A6) LDTP05869 0.60  LDD2132 
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⏷ Show the Full List of 124 Transporter and channel
14 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Cyclic AMP-dependent transcription factor ATF-1 (ATF1) LDTP02967 0.43  LDD2132 
eIF5-mimic protein 1 (BZW2) LDTP14241 0.66; 0.60  LDD2132 
eIF5-mimic protein 2 (BZW1) LDTP07940 0.59  LDD2132 
Forkhead box protein K1 (FOXK1) LDTP05201 0.60  LDD2132 
Gamma-interferon-inducible protein 16 (IFI16) LDTP06602 0.59; 0.96  LDD2132 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 0.51  LDD2132 
NF-kappa-B-repressing factor (NKRF) LDTP00576 0.60  LDD2132 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 0.61  LDD2132 
Nuclear factor 1 C-type (NFIC) LDTP02296 0.42  LDD2132 
Nucleus accumbens-associated protein 1 (NACC1) LDTP10756 0.86  LDD2132 
Recombining binding protein suppressor of hairless (RBPJ) LDTP05485 0.51  LDD2132 
SAP30-binding protein (SAP30BP) LDTP13305 0.47  LDD2132 
Zinc finger CCCH domain-containing protein 15 (ZC3H15) LDTP09564 0.64  LDD2132 
Zinc finger protein 614 (ZNF614) LDTP15451 0.87  LDD2132 
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⏷ Show the Full List of 14 Transcription factor
5 Immunoglobulin Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Basigin (BSG) LDTP03772 0.84  LDD2132 
CD166 antigen (ALCAM) LDTP05973 0.75  LDD2132 
Intercellular adhesion molecule 1 (ICAM1) LDTP02106 0.70  LDD2132 
Programmed cell death 1 ligand 1 (CD274) LDTP12930 0.61  LDD2132 
Tapasin (TAPBP) LDTP00671 0.53  LDD2132 
------------------------------------------------------------------------------------
1 Cytokine and receptor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Endoglin (ENG) LDTP02923 0.47; 0.83  LDD2132 
------------------------------------------------------------------------------------
363 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein eta (YWHAH) LDTP05442 0.96  LDD2132 
182 kDa tankyrase-1-binding protein (TNKS1BP1) LDTP11597 0.66  LDD2132 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 0.51  LDD2132 
26S proteasome non-ATPase regulatory subunit 6 (PSMD6) LDTP06273 0.73  LDD2132 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 0.47  LDD2132 
Actin filament-associated protein 1-like 2 (AFAP1L2) LDTP08879 0.68  LDD2132 
Actin-related protein 2 (ACTR2) LDTP04903 0.69  LDD2132 
Actin-related protein 2/3 complex subunit 1B (ARPC1B) LDTP00550 0.43; 0.55  LDD2132 
Actin-related protein 2/3 complex subunit 2 (ARPC2) LDTP00551 0.49  LDD2132 
Actin-related protein 2/3 complex subunit 3 (ARPC3) LDTP00552 0.56  LDD2132 
Actin-related protein 3 (ACTR3) LDTP04902 0.60; 0.56  LDD2132 
Active breakpoint cluster region-related protein (ABR) LDTP05713 0.39; 0.56  LDD2132 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 0.55; 0.69; 0.49 ...  LDD2132 
Adipose-secreted signaling protein (ADISSP) LDTP18359 0.69  LDD2132 
ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) LDTP08950 0.72  LDD2132 
ADP-ribosylation factor GTPase-activating protein 2 (ARFGAP2) LDTP08935 0.39  LDD2132 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 0.59  LDD2132 
Alpha-actinin-1 (ACTN1) LDTP02631 0.59; 0.44  LDD2132 
Alpha-actinin-4 (ACTN4) LDTP00843 0.93  LDD2132 
Alpha-catulin (CTNNAL1) LDTP13159 0.51  LDD2132 
Alpha-centractin (ACTR1A) LDTP04904 0.42  LDD2132 
Alpha-parvin (PARVA) LDTP12671 0.69  LDD2132 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 0.51; 0.52  LDD2132 
Anamorsin (CIAPIN1) LDTP07385 0.66  LDD2132 
Astrocytic phosphoprotein PEA-15 (PEA15) LDTP06323 0.53  LDD2132 
Ataxin-10 (ATXN10) LDTP13091 0.69  LDD2132 
Band 4.1-like protein 2 (EPB41L2) LDTP00778 0.72  LDD2132 
Bcl-2-associated transcription factor 1 (BCLAF1) LDTP12826 0.72  LDD2132 
Beta-soluble NSF attachment protein (NAPB) LDTP11744 1.49  LDD2132 
Bifunctional purine biosynthesis protein ATIC (ATIC) LDTP03612 0.44  LDD2132 
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 (BAIAP2L2) LDTP07720 0.50  LDD2132 
BRCA2 and CDKN1A-interacting protein (BCCIP) LDTP13030 0.36  LDD2132 
BRO1 domain-containing protein BROX (BROX) LDTP07234 0.49  LDD2132 
Calponin-2 (CNN2) LDTP10864 0.61  LDD2132 
Caprin-1 (CAPRIN1) LDTP06121 0.55  LDD2132 
Catenin alpha-1 (CTNNA1) LDTP03711 0.67; 0.39; 0.59  LDD2132 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 0.52; 0.44; 0.99  LDD2132 
CCN family member 1 (CCN1) LDTP00323 0.53  LDD2132 
CD59 glycoprotein (CD59) LDTP02704 0.94  LDD2132 
Centromere/kinetochore protein zw10 homolog (ZW10) LDTP00720 0.74; 0.47  LDD2132 
Charged multivesicular body protein 5 (CHMP5) LDTP12948 0.35  LDD2132 
Cleavage and polyadenylation specificity factor subunit 6 (CPSF6) LDTP06584 0.27; 0.47  LDD2132 
Cleavage stimulation factor subunit 2 (CSTF2) LDTP03665 0.43  LDD2132 
Cleavage stimulation factor subunit 2 tau variant (CSTF2T) LDTP11718 0.62  LDD2132 
Clustered mitochondria protein homolog (CLUH) LDTP14486 0.72  LDD2132 
Coactosin-like protein (COTL1) LDTP06024 0.40  LDD2132 
Coatomer subunit alpha (COPA) LDTP04571 0.55  LDD2132 
Coatomer subunit beta (COPB1) LDTP04570 0.53; 0.66; 0.45 ...  LDD2132 
Coatomer subunit delta (ARCN1) LDTP04181 0.67; 0.61; 0.93  LDD2132 
Coatomer subunit gamma-1 (COPG1) LDTP14216 0.67; 0.66  LDD2132 
Cofilin-1 (CFL1) LDTP03244 0.55; 0.76; 0.58 ...  LDD2132 
Coiled-coil domain-containing protein 112 (CCDC112) LDTP15508 0.34  LDD2132 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 0.44; 0.43  LDD2132 
COMM domain-containing protein 4 (COMMD4) LDTP11692 1.08  LDD2132 
Condensin complex subunit 1 (NCAPD2) LDTP06281 0.81  LDD2132 
Condensin complex subunit 3 (NCAPG) LDTP11040 0.44; 0.47  LDD2132 
Conserved oligomeric Golgi complex subunit 1 (COG1) LDTP09549 0.30  LDD2132 
Constitutive coactivator of PPAR-gamma-like protein 1 (FAM120A) LDTP12883 1.03  LDD2132 
COP9 signalosome complex subunit 2 (COPS2) LDTP04906 0.69  LDD2132 
Copper transport protein ATOX1 (ATOX1) LDTP00229 0.36  LDD2132 
Core histone macro-H2A.1 (MACROH2A1) LDTP01195 0.43  LDD2132 
Coronin-1B (CORO1B) LDTP11101 0.45; 0.45; 0.43  LDD2132 
Coronin-1C (CORO1C) LDTP13580 0.81; 0.46; 0.43  LDD2132 
CUGBP Elav-like family member 1 (CELF1) LDTP09913 0.65; 0.66  LDD2132 
Cysteine and glycine-rich protein 1 (CSRP1) LDTP03106 0.83; 1.14  LDD2132 
Cysteine and histidine-rich domain-containing protein 1 (CHORDC1) LDTP13269 0.60; 0.51  LDD2132 
Cysteine-rich hydrophobic domain-containing protein 2 (CHIC2) LDTP13458 0.67  LDD2132 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 0.55; 0.59; 0.59 ...  LDD2132 
Cytoplasmic FMR1-interacting protein 1 (CYFIP1) LDTP07958 0.53  LDD2132 
Cytoskeleton-associated protein 5 (CKAP5) LDTP06021 0.61; 0.76; 0.71 ...  LDD2132 
Cytosolic Fe-S cluster assembly factor NUBP1 (NUBP1) LDTP04560 0.55  LDD2132 
Cytosolic Fe-S cluster assembly factor NUBP2 (NUBP2) LDTP14179 0.41  LDD2132 
DAZ-associated protein 1 (DAZAP1) LDTP10271 0.41; 0.41  LDD2132 
Dedicator of cytokinesis protein 7 (DOCK7) LDTP10613 0.42  LDD2132 
Destrin (DSTN) LDTP04887 1.25; 0.52; 0.49 ...  LDD2132 
DNA damage-binding protein 1 (DDB1) LDTP06543 0.37  LDD2132 
DNA fragmentation factor subunit alpha (DFFA) LDTP00239 0.70  LDD2132 
DNA mismatch repair protein Msh6 (MSH6) LDTP04518 0.67  LDD2132 
DnaJ homolog subfamily A member 2 (DNAJA2) LDTP01073 0.34  LDD2132 
DnaJ homolog subfamily C member 7 (DNAJC7) LDTP10920 0.49; 0.84  LDD2132 
Dynactin subunit 1 (DCTN1) LDTP06082 0.67  LDD2132 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 0.59  LDD2132 
ELAV-like protein 1 (ELAVL1) LDTP06450 0.45  LDD2132 
ELAV-like protein 2 (ELAVL2) LDTP14824 0.51  LDD2132 
Elongation factor 1-gamma (EEF1G) LDTP03367 0.88; 0.54  LDD2132 
Elongin-B (ELOB) LDTP06369 1.07  LDD2132 
Epsin-1 (EPN1) LDTP14256 0.56  LDD2132 
Eukaryotic peptide chain release factor subunit 1 (ETF1) LDTP04993 0.92  LDD2132 
Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX) LDTP04129 0.35  LDD2132 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 0.53; 0.44; 0.68 ...  LDD2132 
Eukaryotic translation initiation factor 2A (EIF2A) LDTP11436 0.53; 0.73  LDD2132 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 0.55; 0.56; 0.48 ...  LDD2132 
Eukaryotic translation initiation factor 3 subunit B (EIF3B) LDTP04718 0.51  LDD2132 
Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 0.70  LDD2132 
Eukaryotic translation initiation factor 3 subunit D (EIF3D) LDTP00619 0.47  LDD2132 
Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 1.14  LDD2132 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 0.45  LDD2132 
Eukaryotic translation initiation factor 3 subunit J (EIF3J) LDTP01320 0.66  LDD2132 
Eukaryotic translation initiation factor 3 subunit K (EIF3K) LDTP13143 1.21; 0.65  LDD2132 
Eukaryotic translation initiation factor 3 subunit M (EIF3M) LDTP07947 0.75; 0.66; 0.63  LDD2132 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 0.80  LDD2132 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 0.60; 0.41  LDD2132 
Eukaryotic translation initiation factor 6 (EIF6) LDTP04743 0.58; 1.72; 0.54  LDD2132 
Exosome complex component RRP40 (EXOSC3) LDTP12434 0.44  LDD2132 
F-actin-capping protein subunit beta (CAPZB) LDTP04127 0.61  LDD2132 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 0.43; 0.24; 0.27  LDD2132 
Far upstream element-binding protein 3 (FUBP3) LDTP10408 0.60  LDD2132 
FAS-associated factor 2 (FAF2) LDTP10185 0.77  LDD2132 
Four and a half LIM domains protein 2 (FHL2) LDTP06077 0.49  LDD2132 
Galectin-1 (LGALS1) LDTP02341 0.49; 0.59; 0.70  LDD2132 
Gem-associated protein 4 (GEMIN4) LDTP04790 0.51  LDD2132 
General transcription factor IIH subunit 2-like protein (GTF2H2C; GTF2H2C_2) LDTP15107 0.58  LDD2132 
General transcription factor IIH subunit 4 (GTF2H4) LDTP09861 0.52  LDD2132 
General vesicular transport factor p115 (USO1) LDTP01048 0.63  LDD2132 
Glutamate-rich WD repeat-containing protein 1 (GRWD1) LDTP11058 0.74  LDD2132 
GrpE protein homolog 1, mitochondrial (GRPEL1) LDTP12144 0.55  LDD2132 
Guanine nucleotide-binding protein subunit beta-like protein 1 (GNB1L) LDTP18337 0.50  LDD2132 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 0.36; 0.65; 0.62  LDD2132 
Heat shock protein 105 kDa (HSPH1) LDTP09811 0.55; 0.57; 0.51 ...  LDD2132 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 0.43; 0.69  LDD2132 
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) LDTP00490 0.52  LDD2132 
Hepatoma-derived growth factor (HDGF) LDTP04483 0.52; 0.37  LDD2132 
Heterochromatin protein 1-binding protein 3 (HP1BP3) LDTP07068 0.46  LDD2132 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 0.71  LDD2132 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 0.58  LDD2132 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 0.45  LDD2132 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 0.51; 0.43  LDD2132 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 0.49  LDD2132 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 0.91; 0.80  LDD2132 
Heterogeneous nuclear ribonucleoprotein L (HNRNPL) LDTP02750 0.76  LDD2132 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 0.47; 0.57; 0.46 ...  LDD2132 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 0.58; 0.51  LDD2132 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 0.71; 0.84; 0.63 ...  LDD2132 
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) LDTP11238 0.51; 0.44  LDD2132 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 0.55; 0.75  LDD2132 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 0.39  LDD2132 
Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) LDTP02227 0.42  LDD2132 
Histone-binding protein RBBP4 (RBBP4) LDTP05590 0.43  LDD2132 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 0.53  LDD2132 
Integrin alpha-2 (ITGA2) LDTP02893 0.48  LDD2132 
Integrin alpha-3 (ITGA3) LDTP03342 0.79; 0.44  LDD2132 
Interferon-induced protein with tetratricopeptide repeats 5 (IFIT5) LDTP05828 0.64  LDD2132 
Interleukin enhancer-binding factor 3 (ILF3) LDTP05689 0.37  LDD2132 
Kinesin light chain 2 (KLC2) LDTP11695 0.35  LDD2132 
Large ribosomal subunit protein eL14 (RPL14) LDTP04389 0.47  LDD2132 
Large ribosomal subunit protein eL18 (RPL18) LDTP05509 0.43; 0.90  LDD2132 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 0.41; 0.56; 0.55 ...  LDD2132 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 0.77; 0.70  LDD2132 
Large ribosomal subunit protein eL30 (RPL30) LDTP05021 0.43  LDD2132 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 0.56; 0.99  LDD2132 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 0.84  LDD2132 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 0.91; 0.53; 0.40  LDD2132 
Large ribosomal subunit protein eL36 (RPL36) LDTP14012 3.50  LDD2132 
Large ribosomal subunit protein eL37 (RPL37) LDTP04943 0.43; 0.47  LDD2132 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 1.78  LDD2132 
Large ribosomal subunit protein eL8 (RPL7A) LDTP04990 0.48  LDD2132 
Large ribosomal subunit protein mL38 (MRPL38) LDTP10232 0.43  LDD2132 
Large ribosomal subunit protein uL1 (RPL10A) LDTP05024 0.53  LDD2132 
Large ribosomal subunit protein uL10 (RPLP0) LDTP02109 0.61; 0.46  LDD2132 
Large ribosomal subunit protein uL11 (RPL12) LDTP03517 0.46; 0.33; 0.57  LDD2132 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 1.07; 0.71  LDD2132 
Large ribosomal subunit protein uL15 (RPL27A) LDTP04105 0.59  LDD2132 
Large ribosomal subunit protein uL18 (RPL5) LDTP04106 0.89  LDD2132 
Large ribosomal subunit protein uL24m (MRPL24) LDTP15687 1.18  LDD2132 
Large ribosomal subunit protein uL3 (RPL3) LDTP03865 0.74; 0.60; 0.57 ...  LDD2132 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 0.55  LDD2132 
Large ribosomal subunit protein uL5 (RPL11) LDTP05026 0.51; 0.47  LDD2132 
Large ribosomal subunit protein uL6 (RPL9; RPL9P7; RPL9P8; RPL9P9) LDTP03658 0.55; 0.59  LDD2132 
LEM domain-containing protein 2 (LEMD2) LDTP09082 0.44; 0.40  LDD2132 
Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) LDTP03997 0.58; 0.62; 0.50 ...  LDD2132 
Leucine-rich repeat-containing protein 40 (LRRC40) LDTP19976 0.44  LDD2132 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 0.93; 0.35  LDD2132 
LIM domain and actin-binding protein 1 (LIMA1) LDTP13260 0.69  LDD2132 
Lipid droplet-regulating VLDL assembly factor AUP1 (AUP1) LDTP14217 0.39  LDD2132 
Malignant T-cell-amplified sequence 1 (MCTS1) LDTP13532 0.47  LDD2132 
Matrin-3 (MATR3) LDTP04027 0.70; 0.34; 1.21 ...  LDD2132 
Metallothionein-1X (MT1X) LDTP05159 1.04; 0.87; 0.95  LDD2132 
Methylosome protein WDR77 (WDR77) LDTP11066 0.74  LDD2132 
MICOS complex subunit MIC19 (CHCHD3) LDTP12764 0.55  LDD2132 
Microtubule-associated protein 4 (MAP4) LDTP03404 0.61; 0.56; 0.49  LDD2132 
Mini-chromosome maintenance complex-binding protein (MCMBP) LDTP11197 0.48; 0.45  LDD2132 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 0.81  LDD2132 
MKI67 FHA domain-interacting nucleolar phosphoprotein (NIFK) LDTP11457 1.90  LDD2132 
MOB kinase activator 1A (MOB1A) LDTP12065 0.95  LDD2132 
Muscleblind-like protein 1 (MBNL1) LDTP12478 0.42  LDD2132 
Myb-binding protein 1A (MYBBP1A) LDTP11079 0.58; 0.75; 0.54  LDD2132 
Neuroblast differentiation-associated protein AHNAK (AHNAK) LDTP05597 0.73; 0.40; 0.54 ...  LDD2132 
NHP2-like protein 1 (SNU13) LDTP04708 0.68  LDD2132 
Nonsense-mediated mRNA decay factor SMG8 (SMG8) LDTP09112 0.56  LDD2132 
Nonsense-mediated mRNA decay factor SMG9 (SMG9) LDTP11737 0.68  LDD2132 
Notchless protein homolog 1 (NLE1) LDTP12701 1.02  LDD2132 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 0.43  LDD2132 
Nuclear mitotic apparatus protein 1 (NUMA1) LDTP06244 0.58; 0.58; 0.55 ...  LDD2132 
Nuclear receptor 2C2-associated protein (NR2C2AP) LDTP08338 0.54  LDD2132 
Nuclear transport factor 2 (NUTF2) LDTP04951 0.75  LDD2132 
Nucleolar complex protein 2 homolog (NOC2L) LDTP14011 0.61  LDD2132 
Nucleolar protein 11 (NOL11) LDTP16017 0.56  LDD2132 
Nucleolar protein 16 (NOP16) LDTP16278 0.62  LDD2132 
Nucleolar protein 56 (NOP56) LDTP00313 0.68  LDD2132 
Nucleolin (NCL) LDTP02990 0.35  LDD2132 
Nucleophosmin (NPM1) LDTP02164 0.44  LDD2132 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 0.63; 0.41  LDD2132 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 0.53  LDD2132 
NudC domain-containing protein 1 (NUDCD1) LDTP10781 0.48; 0.77  LDD2132 
Ovarian cancer-related protein 1 (OCR1) LDTP20391 0.49  LDD2132 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 0.28  LDD2132 
Plastin-2 (LCP1) LDTP02691 0.37; 0.57; 0.44 ...  LDD2132 
Pleckstrin homology domain-containing family O member 2 (PLEKHO2) LDTP18061 0.38  LDD2132 
Plectin (PLEC) LDTP06330 0.38; 0.77; 0.42  LDD2132 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 0.54; 0.39; 0.71  LDD2132 
Poly(rC)-binding protein 3 (PCBP3) LDTP04793 0.48  LDD2132 
Polyadenylate-binding protein 3 (PABPC3) LDTP11862 0.57  LDD2132 
Polymerase delta-interacting protein 2 (POLDIP2) LDTP13906 0.62  LDD2132 
Pre-mRNA-processing factor 6 (PRPF6) LDTP01456 0.66  LDD2132 
Pre-mRNA-processing-splicing factor 8 (PRPF8) LDTP07526 0.52  LDD2132 
Pre-mRNA-splicing factor 38B (PRPF38B) LDTP17266 0.40  LDD2132 
Prelamin-A/C (LMNA) LDTP01932 0.37  LDD2132 
Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 0.56; 0.54; 0.66  LDD2132 
Proliferating cell nuclear antigen (PCNA) LDTP02596 0.46; 0.57  LDD2132 
Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) LDTP08707 0.42  LDD2132 
Proline-rich AKT1 substrate 1 (AKT1S1) LDTP10111 0.47  LDD2132 
Proteasomal ubiquitin receptor ADRM1 (ADRM1) LDTP06514 0.57; 0.60  LDD2132 
Proteasome assembly chaperone 2 (PSMG2) LDTP10035 0.37  LDD2132 
Protein CMSS1 (CMSS1) LDTP18287 0.65  LDD2132 
Protein FAM98A (FAM98A) LDTP09086 0.77  LDD2132 
Protein flightless-1 homolog (FLII) LDTP05734 0.52  LDD2132 
Protein IWS1 homolog (IWS1) LDTP10822 0.49  LDD2132 
Protein LSM12 (LSM12) LDTP06780 0.83  LDD2132 
Protein MON2 homolog (MON2) LDTP08041 0.49  LDD2132 
Protein Niban 1 (NIBAN1) LDTP11559 0.58  LDD2132 
Protein Niban 2 (NIBAN2) LDTP10847 0.65; 0.57; 0.47 ...  LDD2132 
Protein RCC2 (RCC2) LDTP13020 0.83; 0.47; 0.62  LDD2132 
Protein strawberry notch homolog 1 (SBNO1) LDTP14337 0.60  LDD2132 
Protein THEM6 (THEM6) LDTP19831 1.14  LDD2132 
Protein transport protein Sec23B (SEC23B) LDTP06391 0.52  LDD2132 
Protein unc-13 homolog D (UNC13D) LDTP07888 0.55; 0.56  LDD2132 
Protein unc-45 homolog A (UNC45A) LDTP11890 1.13; 0.54  LDD2132 
Protein ZNRD2 (ZNRD2) LDTP00916 0.45  LDD2132 
Pumilio homolog 3 (PUM3) LDTP06377 0.47  LDD2132 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 0.56; 0.52  LDD2132 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 0.52; 0.66; 0.56  LDD2132 
Rac GTPase-activating protein 1 (RACGAP1) LDTP11712 0.82  LDD2132 
Raftlin (RFTN1) LDTP06193 0.65  LDD2132 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 0.34; 0.56  LDD2132 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 0.46; 1.12  LDD2132 
Ras GTPase-activating-like protein IQGAP3 (IQGAP3) LDTP08288 0.46  LDD2132 
Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) LDTP07878 0.41  LDD2132 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 0.73  LDD2132 
Regulator of chromosome condensation (RCC1) LDTP02964 0.74  LDD2132 
Regulator of nonsense transcripts 3A (UPF3A) LDTP11767 0.87  LDD2132 
Replication protein A 32 kDa subunit (RPA2) LDTP02816 0.52  LDD2132 
Replication termination factor 2 (RTF2) LDTP11434 0.47  LDD2132 
Retinoblastoma-associated protein (RB1) LDTP02146 0.55  LDD2132 
Ribonuclease inhibitor (RNH1) LDTP02656 0.51; 0.62; 1.04  LDD2132 
Ribosomal L1 domain-containing protein 1 (RSL1D1) LDTP01379 0.41; 0.70; 0.57 ...  LDD2132 
Ribosomal protein eS27-like (RPS27L) LDTP07909 0.39  LDD2132 
Ribosomal protein uL16-like (RPL10L) LDTP10525 0.85; 0.55  LDD2132 
Ribosomal RNA processing protein 1 homolog A (RRP1) LDTP04729 0.62  LDD2132 
Ribosome biogenesis protein BOP1 (BOP1) LDTP06046 0.44  LDD2132 
Ribosome biogenesis protein BRX1 homolog (BRIX1) LDTP15609 0.67; 1.67  LDD2132 
Ribosome-binding protein 1 (RRBP1) LDTP13044 0.56; 0.55  LDD2132 
RING finger protein 214 (RNF214) LDTP19787 0.41  LDD2132 
RNA polymerase-associated protein RTF1 homolog (RTF1) LDTP09786 2.62  LDD2132 
RNA-binding protein 12 (RBM12) LDTP16096 0.46  LDD2132 
RNA-binding protein 25 (RBM25) LDTP04294 0.54  LDD2132 
RNA-binding protein FXR1 (FXR1) LDTP04395 1.05; 0.70  LDD2132 
RNA-binding protein FXR2 (FXR2) LDTP04396 0.51  LDD2132 
RNA-binding protein Raly (RALY) LDTP13467 1.01  LDD2132 
RNA-binding protein RO60 (RO60) LDTP02480 0.58  LDD2132 
Scaffold attachment factor B1 (SAFB) LDTP06385 0.80; 0.74  LDD2132 
Semaphorin-4B (SEMA4B) LDTP12382 0.31  LDD2132 
Sequestosome-1 (SQSTM1) LDTP05898 0.72  LDD2132 
Serine-threonine kinase receptor-associated protein (STRAP) LDTP13991 0.75  LDD2132 
Serine/arginine repetitive matrix protein 2 (SRRM2) LDTP13746 0.47  LDD2132 
Serine/arginine-rich splicing factor 1 (SRSF1) LDTP05539 0.53  LDD2132 
Serine/arginine-rich splicing factor 11 (SRSF11) LDTP05458 0.73  LDD2132 
Serine/arginine-rich splicing factor 3 (SRSF3) LDTP05197 0.97  LDD2132 
Serine/arginine-rich splicing factor 7 (SRSF7) LDTP06583 0.86  LDD2132 
Serine/threonine-protein phosphatase 6 regulatory subunit 3 (PPP6R3) LDTP06983 0.53; 0.56  LDD2132 
Serpin B9 (SERPINB9) LDTP04362 0.61; 0.67  LDD2132 
Serpin H1 (SERPINH1) LDTP04363 0.36  LDD2132 
Serrate RNA effector molecule homolog (SRRT) LDTP11398 0.70; 0.97; 0.53 ...  LDD2132 
Sister chromatid cohesion protein PDS5 homolog A (PDS5A) LDTP06684 0.83; 0.50  LDD2132 
Small nuclear ribonucleoprotein Sm D2 (SNRPD2) LDTP04982 0.67; 0.35  LDD2132 
Small nuclear ribonucleoprotein Sm D3 (SNRPD3) LDTP04983 0.62  LDD2132 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 0.85; 0.37; 0.55 ...  LDD2132 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 1.24; 1.18; 0.86 ...  LDD2132 
Small ribosomal subunit protein eS17 (RPS17) LDTP02302 0.49  LDD2132 
Small ribosomal subunit protein eS21 (RPS21) LDTP05055 0.44; 0.33  LDD2132 
Small ribosomal subunit protein eS25 (RPS25) LDTP05013 0.48  LDD2132 
Small ribosomal subunit protein eS26 (RPS26) LDTP05014 0.72  LDD2132 
Small ribosomal subunit protein eS28 (RPS28) LDTP05015 0.52  LDD2132 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 0.66; 0.79  LDD2132 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 0.54; 0.81  LDD2132 
Small ribosomal subunit protein mS27 (MRPS27) LDTP09793 0.56  LDD2132 
Small ribosomal subunit protein uS10 (RPS20) LDTP04880 0.38; 0.48  LDD2132 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 0.49; 0.58  LDD2132 
Small ribosomal subunit protein uS2 (RPSA) LDTP02312 0.40; 0.58  LDD2132 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 0.49; 0.56; 0.62  LDD2132 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 0.51  LDD2132 
Small ribosomal subunit protein uS8 (RPS15A) LDTP04965 0.42; 0.46  LDD2132 
Small ribosomal subunit protein uS9 (RPS16) LDTP04966 0.40  LDD2132 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 0.59  LDD2132 
Small subunit processome component 20 homolog (UTP20) LDTP01294 1.48  LDD2132 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 0.49  LDD2132 
Splicing factor 1 (SF1) LDTP06429 0.28  LDD2132 
Splicing factor 3B subunit 1 (SF3B1) LDTP01251 0.53  LDD2132 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 0.68  LDD2132 
Splicing factor 45 (RBM17) LDTP10409 0.61  LDD2132 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 0.71; 0.75  LDD2132 
SPRY domain-containing protein 7 (SPRYD7) LDTP07269 0.68  LDD2132 
Squamous cell carcinoma antigen recognized by T-cells 3 (SART3) LDTP06280 0.41  LDD2132 
Src substrate cortactin (CTTN) LDTP06094 0.67; 0.49  LDD2132 
Stalled ribosome sensor GCN1 (GCN1) LDTP09821 0.67; 0.56; 0.44 ...  LDD2132 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 0.49; 0.46; 0.46  LDD2132 
Striatin (STRN) LDTP00875 0.81  LDD2132 
Striatin-4 (STRN4) LDTP12519 0.60  LDD2132 
Survival motor neuron protein (SMN1; SMN2) LDTP06587 0.45  LDD2132 
Symplekin (SYMPK) LDTP09878 0.54  LDD2132 
Synaptophysin-like protein 1 (SYPL1) LDTP06557 0.63  LDD2132 
Synembryn-A (RIC8A) LDTP12381 0.93; 0.59  LDD2132 
T-complex protein 1 subunit alpha (TCP1) LDTP02934 0.75; 0.73; 0.61 ...  LDD2132 
T-complex protein 1 subunit beta (CCT2) LDTP05113 0.96  LDD2132 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 0.54; 0.78; 0.55 ...  LDD2132 
T-complex protein 1 subunit eta (CCT7) LDTP10990 0.64; 0.47; 0.55 ...  LDD2132 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 0.62; 0.66; 0.42 ...  LDD2132 
T-complex protein 1 subunit theta (CCT8) LDTP04390 0.59; 0.53; 0.64  LDD2132 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 0.48  LDD2132 
TAR DNA-binding protein 43 (TARDBP) LDTP05767 0.52  LDD2132 
Testin (TES) LDTP13227 0.59  LDD2132 
Tetratricopeptide repeat protein 4 (TTC4) LDTP01678 0.56  LDD2132 
THUMP domain-containing protein 1 (THUMPD1) LDTP12780 0.86  LDD2132 
Torsin-1A-interacting protein 2 (TOR1AIP2) LDTP09215 1.39; 0.42  LDD2132 
Transforming growth factor-beta-induced protein ig-h3 (TGFBI) LDTP06420 0.45  LDD2132 
Transgelin-2 (TAGLN2) LDTP03846 0.56  LDD2132 
Translation initiation factor eIF2B subunit alpha (EIF2B1) LDTP06088 0.58; 0.50  LDD2132 
Translationally-controlled tumor protein (TPT1) LDTP02683 0.63; 0.62  LDD2132 
Tropomodulin-3 (TMOD3) LDTP18494 0.45  LDD2132 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 0.38  LDD2132 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 0.26  LDD2132 
Tubulin beta-6 chain (TUBB6) LDTP11233 0.46  LDD2132 
Tubulin-folding cofactor B (TBCB) LDTP10860 0.86; 0.40  LDD2132 
Tubulin-specific chaperone D (TBCD) LDTP11212 0.61  LDD2132 
Twinfilin-2 (TWF2) LDTP07404 0.50; 0.56  LDD2132 
U1 small nuclear ribonucleoprotein C (SNRPC) LDTP02335 0.30  LDD2132 
U2 snRNP-associated SURP motif-containing protein (U2SURP) LDTP00517 0.52  LDD2132 
U3 small nucleolar ribonucleoprotein protein MPP10 (MPHOSPH10) LDTP00312 0.54  LDD2132 
U3 small nucleolar RNA-associated protein 18 homolog (UTP18) LDTP14122 0.34; 0.51  LDD2132 
U4/U6 small nuclear ribonucleoprotein Prp3 (PRPF3) LDTP00757 0.50  LDD2132 
Ubiquitin-like protein 5 (UBL5) LDTP11545 0.31  LDD2132 
Ubiquitin-ribosomal protein eS31 fusion protein (RPS27A) LDTP05033 1.44  LDD2132 
Vacuolar protein sorting-associated protein 53 homolog (VPS53) LDTP07206 0.43  LDD2132 
Vasodilator-stimulated phosphoprotein (VASP) LDTP04372 0.78  LDD2132 
Vigilin (HDLBP) LDTP05239 0.63; 0.33; 0.68  LDD2132 
Vimentin (VIM) LDTP02297 0.37  LDD2132 
Vinculin (VCL) LDTP02946 0.75; 0.39; 0.50 ...  LDD2132 
WD repeat-containing protein 1 (WDR1) LDTP01118 0.51  LDD2132 
WD repeat-containing protein 43 (WDR43) LDTP06305 0.43; 0.52  LDD2132 
WD40 repeat-containing protein SMU1 (SMU1) LDTP06726 0.37  LDD2132 
Wings apart-like protein homolog (WAPL) LDTP08094 0.60; 0.86  LDD2132 
Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) LDTP08018 0.98  LDD2132 
Zinc finger protein 185 (ZNF185) LDTP00580 0.47  LDD2132 
Zyxin (ZYX) LDTP06507 0.30  LDD2132 
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Full Information of The Labelling Profiles of This Competitor

Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 5 mM
Quantitative Method Isotope tag
Experimemt Name ISO-TOP ABPP
Competitor Name 3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile
Competitor Concentration 0.5 mM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cell lysate (MDA-MB-231)
Interaction Atlas ID  LDD2132  Download The Altas

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761