Details of the Target

General Information of Target

Target ID LDTP03537
Target Name Glycylpeptide N-tetradecanoyltransferase 1 (NMT1)
Gene Name NMT1
Gene ID 4836
Synonyms
NMT; Glycylpeptide N-tetradecanoyltransferase 1; EC 2.3.1.97; Myristoyl-CoA:protein N-myristoyltransferase 1; HsNMT1; NMT 1; Type I N-myristoyltransferase; Peptide N-myristoyltransferase 1; Protein-lysine myristoyltransferase NMT1; EC 2.3.1.-
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MADESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKK
QKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFW
DTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENY
VEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEK
KMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRS
LNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQF
HLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAY
SFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYN
WKCPSMGAEKVGLVLQ
Target Bioclass
Enzyme
Family
NMT family
Subcellular location
Cytoplasm
Function
Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins . Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2' and 'Lys-3'. Lysine myristoylation is required to maintain ARF6 on membranes during the GTPase cycle.
Uniprot ID
P30419
Ensemble ID
ENST00000258960.7
HGNC ID
HGNC:7857
ChEMBL ID
CHEMBL2593

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
ECC2 SNV: p.R265Q .
KMCH1 SNV: p.R265Ter DBIA    Probe Info 
LNCaP clone FGC SNV: p.E331Ter DBIA    Probe Info 
MEWO SNV: p.P124L .
MOLT4 SNV: p.T122M; p.A160D IA-alkyne    Probe Info 
OPM2 SNV: p.N42S DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 23 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		11.03  LDD0402  [1]
A-EBA
 Probe Info  		4.33  LDD0215  [2]
TH211
 Probe Info  		Y117(10.45); Y420(9.80)  LDD0257  [3]
YN-1
 Probe Info  		100.00  LDD0444  [4]
STPyne
 Probe Info  		K55(10.00); K94(3.90)  LDD0277  [5]
BTD
 Probe Info  		C294(10.82)  LDD1699  [6]
AZ-9
 Probe Info  		E97(1.85)  LDD2209  [7]
Probe 1
 Probe Info  		Y117(13.65); Y150(8.03)  LDD3495  [8]
DBIA
 Probe Info  		C483(2.22)  LDD3333  [9]
AHL-Pu-1
 Probe Info  		C249(4.68)  LDD0171  [10]
IPM
 Probe Info  		C294(21.11); C483(2.55); C249(0.58)  LDD1701  [6]
Acrolein
 Probe Info  		N.A.  LDD0223  [11]
5E-2FA
 Probe Info  		N.A.  LDD2235  [12]
ATP probe
 Probe Info  		N.A.  LDD0199  [13]
4-Iodoacetamidophenylacetylene
 Probe Info  		C483(0.00); C212(0.00); C249(0.00); C294(0.00)  LDD0038  [14]
IA-alkyne
 Probe Info  		C483(0.00); C212(0.00); C249(0.00); C294(0.00)  LDD0036  [14]
Lodoacetamide azide
 Probe Info  		C483(0.00); C212(0.00); C249(0.00); C294(0.00)  LDD0037  [14]
WYneN
 Probe Info  		N.A.  LDD0021  [15]
NHS
 Probe Info  		N.A.  LDD0010  [15]
1c-yne
 Probe Info  		N.A.  LDD0228  [16]
AOyne
 Probe Info  		5.10  LDD0443  [17]
NAIA_5
 Probe Info  		C483(0.00); C294(0.00)  LDD2223  [18]
HHS-482
 Probe Info  		Y117(1.65); Y327(1.02)  LDD2239  [19]
PAL-AfBPP Probe
Click To Hide/Show 9 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C011
 Probe Info  		5.62  LDD1720  [20]
C367
 Probe Info  		6.82  LDD2028  [20]
FFF probe11
 Probe Info  		13.58  LDD0471  [21]
FFF probe13
 Probe Info  		12.41  LDD0475  [21]
FFF probe3
 Probe Info  		16.21  LDD0464  [21]
STS-1
 Probe Info  		1.17  LDD0137  [22]
STS-2
 Probe Info  		N.A.  LDD0138  [22]
DA-2
 Probe Info  		N.A.  LDD0072  [23]
OEA-DA
 Probe Info  		4.09  LDD0046  [24]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C294(0.69)  LDD2142  [6]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C294(0.98)  LDD2112  [6]
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C294(0.57)  LDD2095  [6]
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C294(1.02)  LDD2130  [6]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C294(0.85)  LDD2117  [6]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C294(1.27)  LDD2152  [6]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C294(1.03)  LDD2103  [6]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C294(0.44)  LDD2132  [6]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C294(0.57)  LDD2131  [6]
 LDCM0026  4SU-RNA+native RNA DM93 C249(4.68)  LDD0171  [10]
 LDCM0214  AC1 HEK-293T C483(0.96)  LDD1507  [25]
 LDCM0215  AC10 HEK-293T C483(1.12)  LDD1508  [25]
 LDCM0237  AC12 HEK-293T C483(0.99)  LDD1510  [25]
 LDCM0259  AC14 HEK-293T C483(1.15)  LDD1512  [25]
 LDCM0270  AC15 HEK-293T C483(1.05)  LDD1513  [25]
 LDCM0276  AC17 HEK-293T C483(1.01)  LDD1515  [25]
 LDCM0277  AC18 HEK-293T C483(1.04)  LDD1516  [25]
 LDCM0279  AC2 HEK-293T C483(1.06)  LDD1518  [25]
 LDCM0280  AC20 HEK-293T C483(0.88)  LDD1519  [25]
 LDCM0281  AC21 HEK-293T C483(1.16)  LDD1520  [25]
 LDCM0282  AC22 HEK-293T C483(1.19)  LDD1521  [25]
 LDCM0283  AC23 HEK-293T C483(0.94)  LDD1522  [25]
 LDCM0284  AC24 HEK-293T C483(1.01)  LDD1523  [25]
 LDCM0285  AC25 HEK-293T C483(0.95)  LDD1524  [25]
 LDCM0286  AC26 HEK-293T C483(1.04)  LDD1525  [25]
 LDCM0288  AC28 HEK-293T C483(0.94)  LDD1527  [25]
 LDCM0289  AC29 HEK-293T C483(1.15)  LDD1528  [25]
 LDCM0291  AC30 HEK-293T C483(1.07)  LDD1530  [25]
 LDCM0292  AC31 HEK-293T C483(0.98)  LDD1531  [25]
 LDCM0293  AC32 HEK-293T C483(1.01)  LDD1532  [25]
 LDCM0294  AC33 HEK-293T C483(0.98)  LDD1533  [25]
 LDCM0295  AC34 HEK-293T C483(1.09)  LDD1534  [25]
 LDCM0297  AC36 HEK-293T C483(0.91)  LDD1536  [25]
 LDCM0298  AC37 HEK-293T C483(1.28)  LDD1537  [25]
 LDCM0299  AC38 HEK-293T C483(1.20)  LDD1538  [25]
 LDCM0300  AC39 HEK-293T C483(1.06)  LDD1539  [25]
 LDCM0301  AC4 HEK-293T C483(1.00)  LDD1540  [25]
 LDCM0302  AC40 HEK-293T C483(1.12)  LDD1541  [25]
 LDCM0303  AC41 HEK-293T C483(0.95)  LDD1542  [25]
 LDCM0304  AC42 HEK-293T C483(1.08)  LDD1543  [25]
 LDCM0306  AC44 HEK-293T C483(0.96)  LDD1545  [25]
 LDCM0307  AC45 HEK-293T C483(1.28)  LDD1546  [25]
 LDCM0308  AC46 HEK-293T C483(1.30)  LDD1547  [25]
 LDCM0309  AC47 HEK-293T C483(1.04)  LDD1548  [25]
 LDCM0310  AC48 HEK-293T C483(1.15)  LDD1549  [25]
 LDCM0311  AC49 HEK-293T C483(0.99)  LDD1550  [25]
 LDCM0312  AC5 HEK-293T C483(1.22)  LDD1551  [25]
 LDCM0313  AC50 HEK-293T C483(1.18)  LDD1552  [25]
 LDCM0315  AC52 HEK-293T C483(0.98)  LDD1554  [25]
 LDCM0316  AC53 HEK-293T C483(1.25)  LDD1555  [25]
 LDCM0317  AC54 HEK-293T C483(1.23)  LDD1556  [25]
 LDCM0318  AC55 HEK-293T C483(1.06)  LDD1557  [25]
 LDCM0319  AC56 HEK-293T C483(1.05)  LDD1558  [25]
 LDCM0320  AC57 HEK-293T C483(0.99)  LDD1559  [25]
 LDCM0321  AC58 HEK-293T C483(1.03)  LDD1560  [25]
 LDCM0323  AC6 HEK-293T C483(1.23)  LDD1562  [25]
 LDCM0324  AC60 HEK-293T C483(0.91)  LDD1563  [25]
 LDCM0325  AC61 HEK-293T C483(1.12)  LDD1564  [25]
 LDCM0326  AC62 HEK-293T C483(1.12)  LDD1565  [25]
 LDCM0327  AC63 HEK-293T C483(0.95)  LDD1566  [25]
 LDCM0328  AC64 HEK-293T C483(1.08)  LDD1567  [25]
 LDCM0334  AC7 HEK-293T C483(1.03)  LDD1568  [25]
 LDCM0345  AC8 HEK-293T C483(1.11)  LDD1569  [25]
 LDCM0545  Acetamide MDA-MB-231 C294(0.26)  LDD2138  [6]
 LDCM0248  AKOS034007472 HEK-293T C483(1.18)  LDD1511  [25]
 LDCM0356  AKOS034007680 HEK-293T C483(1.00)  LDD1570  [25]
 LDCM0275  AKOS034007705 HEK-293T C483(1.14)  LDD1514  [25]
 LDCM0156  Aniline NCI-H1299 12.05  LDD0403  [1]
 LDCM0368  CL10 HEK-293T C483(1.14)  LDD1572  [25]
 LDCM0369  CL100 HEK-293T C483(1.13)  LDD1573  [25]
 LDCM0371  CL102 HEK-293T C483(1.00)  LDD1575  [25]
 LDCM0373  CL104 HEK-293T C483(1.10)  LDD1577  [25]
 LDCM0375  CL106 HEK-293T C483(0.84)  LDD1579  [25]
 LDCM0377  CL108 HEK-293T C483(1.00)  LDD1581  [25]
 LDCM0379  CL11 HEK-293T C483(1.03)  LDD1583  [25]
 LDCM0380  CL110 HEK-293T C483(0.95)  LDD1584  [25]
 LDCM0382  CL112 HEK-293T C483(0.98)  LDD1586  [25]
 LDCM0384  CL114 HEK-293T C483(1.65)  LDD1588  [25]
 LDCM0386  CL116 HEK-293T C483(1.11)  LDD1590  [25]
 LDCM0388  CL118 HEK-293T C483(0.98)  LDD1592  [25]
 LDCM0390  CL12 HEK-293T C483(0.96)  LDD1594  [25]
 LDCM0391  CL120 HEK-293T C483(1.19)  LDD1595  [25]
 LDCM0393  CL122 HEK-293T C483(1.04)  LDD1597  [25]
 LDCM0395  CL124 HEK-293T C483(1.12)  LDD1599  [25]
 LDCM0397  CL126 HEK-293T C483(0.90)  LDD1601  [25]
 LDCM0399  CL128 HEK-293T C483(1.02)  LDD1603  [25]
 LDCM0401  CL14 HEK-293T C483(0.99)  LDD1605  [25]
 LDCM0403  CL16 HEK-293T C483(1.03)  LDD1607  [25]
 LDCM0404  CL17 HEK-293T C483(0.94)  LDD1608  [25]
 LDCM0405  CL18 HEK-293T C483(1.01)  LDD1609  [25]
 LDCM0407  CL2 HEK-293T C483(0.95)  LDD1611  [25]
 LDCM0408  CL20 HEK-293T C483(0.99)  LDD1612  [25]
 LDCM0409  CL21 HEK-293T C483(1.07)  LDD1613  [25]
 LDCM0410  CL22 HEK-293T C483(1.23)  LDD1614  [25]
 LDCM0411  CL23 HEK-293T C483(1.06)  LDD1615  [25]
 LDCM0412  CL24 HEK-293T C483(1.10)  LDD1616  [25]
 LDCM0414  CL26 HEK-293T C483(0.99)  LDD1618  [25]
 LDCM0416  CL28 HEK-293T C483(1.00)  LDD1620  [25]
 LDCM0417  CL29 HEK-293T C483(0.99)  LDD1621  [25]
 LDCM0419  CL30 HEK-293T C483(1.00)  LDD1623  [25]
 LDCM0421  CL32 HEK-293T C483(0.95)  LDD1625  [25]
 LDCM0422  CL33 HEK-293T C483(1.15)  LDD1626  [25]
 LDCM0423  CL34 HEK-293T C483(1.23)  LDD1627  [25]
 LDCM0424  CL35 HEK-293T C483(0.99)  LDD1628  [25]
 LDCM0425  CL36 HEK-293T C483(1.10)  LDD1629  [25]
 LDCM0429  CL4 HEK-293T C483(0.97)  LDD1633  [25]
 LDCM0430  CL40 HEK-293T C483(1.00)  LDD1634  [25]
 LDCM0431  CL41 HEK-293T C483(0.99)  LDD1635  [25]
 LDCM0432  CL42 HEK-293T C483(1.14)  LDD1636  [25]
 LDCM0434  CL44 HEK-293T C483(0.93)  LDD1638  [25]
 LDCM0435  CL45 HEK-293T C483(1.10)  LDD1639  [25]
 LDCM0436  CL46 HEK-293T C483(1.21)  LDD1640  [25]
 LDCM0437  CL47 HEK-293T C483(0.97)  LDD1641  [25]
 LDCM0438  CL48 HEK-293T C483(1.03)  LDD1642  [25]
 LDCM0440  CL5 HEK-293T C483(0.98)  LDD1644  [25]
 LDCM0441  CL50 HEK-293T C483(1.10)  LDD1645  [25]
 LDCM0443  CL52 HEK-293T C483(1.22)  LDD1646  [25]
 LDCM0444  CL53 HEK-293T C483(1.02)  LDD1647  [25]
 LDCM0445  CL54 HEK-293T C483(1.16)  LDD1648  [25]
 LDCM0447  CL56 HEK-293T C483(0.93)  LDD1650  [25]
 LDCM0448  CL57 HEK-293T C483(1.30)  LDD1651  [25]
 LDCM0449  CL58 HEK-293T C483(1.26)  LDD1652  [25]
 LDCM0450  CL59 HEK-293T C483(1.17)  LDD1653  [25]
 LDCM0451  CL6 HEK-293T C483(0.94)  LDD1654  [25]
 LDCM0452  CL60 HEK-293T C483(1.14)  LDD1655  [25]
 LDCM0454  CL62 HEK-293T C483(0.95)  LDD1657  [25]
 LDCM0456  CL64 HEK-293T C483(1.17)  LDD1659  [25]
 LDCM0457  CL65 HEK-293T C483(0.94)  LDD1660  [25]
 LDCM0458  CL66 HEK-293T C483(1.05)  LDD1661  [25]
 LDCM0460  CL68 HEK-293T C483(0.98)  LDD1663  [25]
 LDCM0461  CL69 HEK-293T C483(1.18)  LDD1664  [25]
 LDCM0463  CL70 HEK-293T C483(1.19)  LDD1666  [25]
 LDCM0464  CL71 HEK-293T C483(1.12)  LDD1667  [25]
 LDCM0465  CL72 HEK-293T C483(1.06)  LDD1668  [25]
 LDCM0467  CL74 HEK-293T C483(0.95)  LDD1670  [25]
 LDCM0469  CL76 HEK-293T C483(1.13)  LDD1672  [25]
 LDCM0470  CL77 HEK-293T C483(0.99)  LDD1673  [25]
 LDCM0471  CL78 HEK-293T C483(1.14)  LDD1674  [25]
 LDCM0473  CL8 HEK-293T C483(0.75)  LDD1676  [25]
 LDCM0474  CL80 HEK-293T C483(1.14)  LDD1677  [25]
 LDCM0475  CL81 HEK-293T C483(1.25)  LDD1678  [25]
 LDCM0476  CL82 HEK-293T C483(1.28)  LDD1679  [25]
 LDCM0477  CL83 HEK-293T C483(1.17)  LDD1680  [25]
 LDCM0478  CL84 HEK-293T C483(1.21)  LDD1681  [25]
 LDCM0480  CL86 HEK-293T C483(1.04)  LDD1683  [25]
 LDCM0482  CL88 HEK-293T C483(1.10)  LDD1685  [25]
 LDCM0483  CL89 HEK-293T C483(0.97)  LDD1686  [25]
 LDCM0484  CL9 HEK-293T C483(1.20)  LDD1687  [25]
 LDCM0485  CL90 HEK-293T C483(1.14)  LDD1688  [25]
 LDCM0487  CL92 HEK-293T C483(1.00)  LDD1690  [25]
 LDCM0488  CL93 HEK-293T C483(1.26)  LDD1691  [25]
 LDCM0489  CL94 HEK-293T C483(1.25)  LDD1692  [25]
 LDCM0490  CL95 HEK-293T C483(1.16)  LDD1693  [25]
 LDCM0491  CL96 HEK-293T C483(1.17)  LDD1694  [25]
 LDCM0493  CL98 HEK-293T C483(1.05)  LDD1696  [25]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C483(4.41); C294(2.19)  LDD1702  [6]
 LDCM0625  F8 Ramos C483(0.59)  LDD2187  [26]
 LDCM0572  Fragment10 Ramos C483(0.66)  LDD2189  [26]
 LDCM0573  Fragment11 Ramos C483(0.15)  LDD2190  [26]
 LDCM0574  Fragment12 Ramos C483(0.58)  LDD2191  [26]
 LDCM0575  Fragment13 Ramos C483(1.84)  LDD2192  [26]
 LDCM0579  Fragment20 Ramos C483(0.48)  LDD2194  [26]
 LDCM0580  Fragment21 Ramos C483(0.70)  LDD2195  [26]
 LDCM0582  Fragment23 Ramos C483(1.07)  LDD2196  [26]
 LDCM0578  Fragment27 Ramos C483(1.12)  LDD2197  [26]
 LDCM0588  Fragment30 Ramos C483(2.05)  LDD2199  [26]
 LDCM0589  Fragment31 Ramos C483(2.21)  LDD2200  [26]
 LDCM0590  Fragment32 Ramos C483(0.47)  LDD2201  [26]
 LDCM0468  Fragment33 Ramos C483(1.94)  LDD2202  [26]
 LDCM0596  Fragment38 Ramos C483(1.11)  LDD2203  [26]
 LDCM0566  Fragment4 Ramos C483(0.20)  LDD2184  [26]
 LDCM0427  Fragment51 HEK-293T C483(1.17)  LDD1631  [25]
 LDCM0610  Fragment52 Ramos C483(2.06)  LDD2204  [26]
 LDCM0614  Fragment56 Ramos C483(15.42)  LDD2205  [26]
 LDCM0569  Fragment7 Ramos C483(0.12)  LDD2186  [26]
 LDCM0571  Fragment9 Ramos C483(0.59)  LDD2188  [26]
 LDCM0022  KB02 Ramos C483(0.17)  LDD2182  [26]
 LDCM0023  KB03 MDA-MB-231 C294(21.11); C483(2.55); C249(0.58)  LDD1701  [6]
 LDCM0024  KB05 MOLM-13 C483(2.22)  LDD3333  [9]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C294(1.16)  LDD2102  [6]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C294(0.93)  LDD2121  [6]
 LDCM0109  NEM HeLa N.A.  LDD0223  [11]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C294(0.39)  LDD2089  [6]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C294(0.88)  LDD2092  [6]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C294(1.06)  LDD2093  [6]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C294(1.07)  LDD2094  [6]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C294(0.63)  LDD2096  [6]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C294(1.14)  LDD2097  [6]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C294(0.89)  LDD2098  [6]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C294(1.11)  LDD2099  [6]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C294(0.81)  LDD2100  [6]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C294(0.80)  LDD2101  [6]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C294(0.97)  LDD2104  [6]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C294(0.95)  LDD2105  [6]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C294(0.94)  LDD2106  [6]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C294(1.06)  LDD2107  [6]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C294(0.83)  LDD2108  [6]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C294(0.60)  LDD2109  [6]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C294(2.39)  LDD2110  [6]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C294(1.03)  LDD2111  [6]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C294(0.79)  LDD2114  [6]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C294(0.71)  LDD2115  [6]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C294(0.55)  LDD2118  [6]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C294(2.86)  LDD2119  [6]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C294(0.33)  LDD2122  [6]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C294(0.90)  LDD2123  [6]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C294(0.35)  LDD2124  [6]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C294(0.81)  LDD2125  [6]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C294(0.23)  LDD2126  [6]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C294(0.94)  LDD2127  [6]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C294(1.18)  LDD2129  [6]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C294(0.68)  LDD2133  [6]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C294(1.09)  LDD2135  [6]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C294(0.99)  LDD2136  [6]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C294(1.11)  LDD2137  [6]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C294(1.08)  LDD1700  [6]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C294(0.58)  LDD2140  [6]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C294(0.92)  LDD2141  [6]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C294(2.79)  LDD2144  [6]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C294(1.03)  LDD2146  [6]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C294(0.78)  LDD2148  [6]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C294(0.47)  LDD2149  [6]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C294(0.36)  LDD2150  [6]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C294(1.07)  LDD2151  [6]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C294(1.34)  LDD2153  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Acyl-CoA-binding domain-containing protein 6 (ACBD6) . Q9BR61

The Drug(s) Related To This Target

Investigative
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
(1-methyl-1h-imidazol-2-yl)-(3-methyl-4-{3-[(Pyridin-3-ylmethyl)-amino]-propoxy}-benzofuran-2-yl)-methanone . DB03062

References

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Mass spectrometry data entry: PXD037665
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Mass spectrometry data entry: PXD028270
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Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD047840
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Mass spectrometry data entry: PXD044625
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Mass spectrometry data entry: PXD042377
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Mass spectrometry data entry: PXD028853
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Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD007570
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Mass spectrometry data entry: PXD044402
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Mass spectrometry data entry: PXD027578