General Information of Competitor

Competitor ID
LDCM0504
Competitor Name
Nucleophilic fragment 15a
Synonyms
N-1,3-benzodioxol-5-yl-2-cyanoacetamide; 142555-09-7; N-(1,3-benzodioxol-5-yl)-2-cyanoacetamide; N-(Benzo[d][1,3]dioxol-5-yl)-2-cyanoacetamide; N-(2H-1,3-benzodioxol-5-yl)-2-cyanoacetamide; Enamine_002949; Oprea1_016609; DTXSID801278731; HMS1402G01; BBL017190; MFCD03152807; STK441903; AKOS000245250; VS-05933; CS-0305677; Z56827833
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 204.18
Lipid-water partition coefficient (xlogp) 1.2
Rotatable Bond Count (rotbonds) 2
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C10H8N2O3
IUPAC Name
N-(1,3-benzodioxol-5-yl)-2-cyanoacetamide
Canonical SMILES
C1OC2=C(O1)C=C(C=C2)NC(=O)CC#N
InChI
InChI=1S/C10H8N2O3/c11-4-3-10(13)12-7-1-2-8-9(5-7)15-6-14-8/h1-2,5H,3,6H2,(H,12,13)
InChIKey
IPGDELMADGDOMC-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
BTD
 Probe Info 
5 mM Human breast adenocarcinoma cell lysate (MDA-MB-231) [1]

Target(s) List of this Competitor

377 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (PLCB3) LDTP05327 0.85  LDD2097 
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) LDTP02356 0.95  LDD2097 
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (DECR1) LDTP06612 1.00  LDD2097 
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (GCAT) LDTP01268 0.99  LDD2097 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 0.87; 0.69  LDD2097 
26S proteasome non-ATPase regulatory subunit 1 (PSMD1) LDTP10869 0.70; 0.40  LDD2097 
26S proteasome non-ATPase regulatory subunit 12 (PSMD12) LDTP00224 1.31  LDD2097 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 0.95  LDD2097 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 0.98; 1.01; 1.52  LDD2097 
26S proteasome non-ATPase regulatory subunit 9 (PSMD9) LDTP00225 0.88  LDD2097 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 0.92  LDD2097 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 0.55  LDD2097 
26S proteasome regulatory subunit 6A (PSMC3) LDTP02933 0.93; 1.09  LDD2097 
26S proteasome regulatory subunit 7 (PSMC2) LDTP03797 0.98  LDD2097 
26S proteasome regulatory subunit 8 (PSMC5) LDTP04963 1.00  LDD2097 
3'(2'),5'-bisphosphate nucleotidase 1 (BPNT1) LDTP01697 0.77  LDD2097 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 1.03; 0.86  LDD2097 
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (HIBCH) LDTP07483 0.96  LDD2097 
3-ketoacyl-CoA thiolase, peroxisomal (ACAA1) LDTP02329 0.88  LDD2097 
4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) LDTP04232 1.12  LDD2097 
5'-nucleotidase (NT5E) LDTP03120 0.97  LDD2097 
6-phosphogluconate dehydrogenase, decarboxylating (PGD) LDTP04499 1.18  LDD2097 
6-phosphogluconolactonase (PGLS) LDTP14535 0.64; 0.65  LDD2097 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 0.80  LDD2097 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 0.84  LDD2097 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 0.73; 1.18; 0.72  LDD2097 
Aconitate hydratase, mitochondrial (ACO2) LDTP10982 0.84; 0.48  LDD2097 
Actin, cytoplasmic 2 (ACTG1) LDTP05059 0.90  LDD2097 
Acyl-coenzyme A thioesterase 9, mitochondrial (ACOT9) LDTP16274 1.05  LDD2097 
Acylamino-acid-releasing enzyme (APEH) LDTP02693 0.81  LDD2097 
Acylpyruvase FAHD1, mitochondrial (FAHD1) LDTP07540 0.70  LDD2097 
Adenosine 5'-monophosphoramidase HINT1 (HINT1) LDTP04306 0.90  LDD2097 
Adenosylhomocysteinase (AHCY) LDTP03242 0.85; 0.79  LDD2097 
Adenylosuccinate lyase (ADSL) LDTP03551 0.67; 0.97  LDD2097 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 0.80; 0.58  LDD2097 
Aldehyde dehydrogenase 1A1 (ALDH1A1) LDTP01767 0.71; 0.90  LDD2097 
Aldehyde oxidase (AOX1) LDTP05483 0.76  LDD2097 
Aldo-keto reductase family 1 member B1 (AKR1B1) LDTP02765 1.09; 0.97; 0.85 ...  LDD2097 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 0.82; 1.10; 0.92 ...  LDD2097 
All-trans-retinol 13,14-reductase (RETSAT) LDTP15097 0.87  LDD2097 
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (MGAT1) LDTP03362 2.13  LDD2097 
Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) LDTP04253 0.77  LDD2097 
Alpha-enolase (ENO1) LDTP02159 1.69; 0.71  LDD2097 
Aminoacylase-1 (ACY1) LDTP05395 0.79  LDD2097 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 0.99  LDD2097 
Aspartate aminotransferase, mitochondrial (GOT2) LDTP01783 0.73  LDD2097 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 1.20  LDD2097 
Aspartyl/asparaginyl beta-hydroxylase (ASPH) LDTP05652 0.94  LDD2097 
ATP synthase subunit epsilon-like protein, mitochondrial (ATP5F1EP2) LDTP17268 2.95  LDD2097 
ATP-binding cassette sub-family C member 3 (ABCC3) LDTP00638 4.49  LDD2097 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 0.85; 0.87  LDD2097 
ATP-citrate synthase (ACLY) LDTP04561 1.17; 0.71; 0.71  LDD2097 
ATP-dependent 6-phosphofructokinase, platelet type (PFKP) LDTP05314 0.76  LDD2097 
ATP-dependent RNA helicase A (DHX9) LDTP05550 0.87; 1.35; 0.71 ...  LDD2097 
ATP-dependent RNA helicase DDX1 (DDX1) LDTP09766 1.30  LDD2097 
ATP-dependent RNA helicase DDX39A (DDX39A) LDTP00192 0.95; 0.99  LDD2097 
ATP-dependent RNA helicase DDX3Y (DDX3Y) LDTP00664 0.67; 0.89  LDD2097 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 0.48  LDD2097 
ATP-dependent RNA helicase DHX8 (DHX8) LDTP06147 2.02  LDD2097 
ATPase family AAA domain-containing protein 2 (ATAD2) LDTP07607 0.89  LDD2097 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 0.79  LDD2097 
Aurora kinase A (AURKA) LDTP00491 0.69  LDD2097 
Beta-ureidopropionase (UPB1) LDTP13146 1.36  LDD2097 
Betaine--homocysteine S-methyltransferase 1 (BHMT) LDTP09978 0.75  LDD2097 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 0.97  LDD2097 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 0.61; 1.54; 0.85  LDD2097 
Bleomycin hydrolase (BLMH) LDTP05992 1.07  LDD2097 
Branched-chain-amino-acid aminotransferase, cytosolic (BCAT1) LDTP04622 0.68  LDD2097 
Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT2) LDTP00624 0.76  LDD2097 
Calcyclin-binding protein (CACYBP) LDTP12163 0.75  LDD2097 
Calpain-2 catalytic subunit (CAPN2) LDTP02911 0.74  LDD2097 
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (CMTR1) LDTP08773 0.81  LDD2097 
Carbonyl reductase [NADPH] 1 (CBR1) LDTP02831 0.94  LDD2097 
Carboxymethylenebutenolidase homolog (CMBL) LDTP10215 1.05  LDD2097 
Carboxypeptidase D (CPD) LDTP01372 1.02  LDD2097 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 0.76  LDD2097 
Caspase-8 (CASP8) LDTP06211 0.86  LDD2097 
Catalase (CAT) LDTP02001 1.00; 0.78  LDD2097 
Cell division control protein 42 homolog (CDC42) LDTP04886 0.79  LDD2097 
Choline-phosphate cytidylyltransferase A (PCYT1A) LDTP04261 0.66; 1.31  LDD2097 
Chondroitin sulfate synthase 2 (CHPF) LDTP08686 0.85  LDD2097 
Citrate synthase, mitochondrial (CS) LDTP01205 0.78; 0.63  LDD2097 
Complex I assembly factor ACAD9, mitochondrial (ACAD9) LDTP12048 1.06  LDD2097 
COP9 signalosome complex subunit 3 (COPS3) LDTP13675 1.11  LDD2097 
COP9 signalosome complex subunit 5 (COPS5) LDTP09925 0.96  LDD2097 
CTP synthase 1 (CTPS1) LDTP02922 1.77; 0.90  LDD2097 
Cullin-1 (CUL1) LDTP05946 1.00  LDD2097 
Cullin-2 (CUL2) LDTP05947 0.94  LDD2097 
Cullin-3 (CUL3) LDTP05948 1.04; 0.70  LDD2097 
Cullin-4A (CUL4A) LDTP05949 1.00; 1.30  LDD2097 
Cullin-associated NEDD8-dissociated protein 1 (CAND1) LDTP08296 0.92; 0.99  LDD2097 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 1.37  LDD2097 
Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) LDTP03610 1.08  LDD2097 
Cytochrome b-c1 complex subunit 6, mitochondrial (UQCRH) LDTP02229 0.81; 0.98; 1.02 ...  LDD2097 
Cytoplasmic aconitate hydratase (ACO1) LDTP03110 0.98; 0.86; 1.02  LDD2097 
Cytosol aminopeptidase (LAP3) LDTP03455 0.97  LDD2097 
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 1.13  LDD2097 
Cytosolic non-specific dipeptidase (CNDP2) LDTP10514 0.60  LDD2097 
D-dopachrome decarboxylase (DDT) LDTP03513 0.82  LDD2097 
DDB1- and CUL4-associated factor 8 (DCAF8) LDTP07169 0.74  LDD2097 
Delta(24)-sterol reductase (DHCR24) LDTP06375 1.15  LDD2097 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 0.77  LDD2097 
Delta-aminolevulinic acid dehydratase (ALAD) LDTP02684 1.19  LDD2097 
Deoxycytidylate deaminase (DCTD) LDTP03643 0.85  LDD2097 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 0.66  LDD2097 
Deoxyribose-phosphate aldolase (DERA) LDTP13941 1.33  LDD2097 
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) LDTP02362 0.96  LDD2097 
Dipeptidyl peptidase 9 (DPP9) LDTP08198 0.88  LDD2097 
DNA (cytosine-5)-methyltransferase 1 (DNMT1) LDTP03350 0.99  LDD2097 
DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 1.07  LDD2097 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 0.88  LDD2097 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 1.05; 1.18  LDD2097 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 0.52  LDD2097 
DNA topoisomerase 1 (TOP1) LDTP02567 1.05  LDD2097 
DNA-dependent protein kinase catalytic subunit (PRKDC) LDTP05136 0.97; 1.00; 0.99 ...  LDD2097 
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase (ALG3) LDTP09841 0.86  LDD2097 
Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) LDTP13087 1.03  LDD2097 
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) LDTP04103 0.83  LDD2097 
Dynamin-1-like protein (DNM1L) LDTP00273 0.72; 0.87  LDD2097 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 1.19  LDD2097 
E3 SUMO-protein ligase RanBP2 (RANBP2) LDTP04310 1.44; 1.62; 1.30  LDD2097 
E3 ubiquitin-protein ligase HUWE1 (HUWE1) LDTP08135 0.99  LDD2097 
E3 ubiquitin-protein ligase SMURF2 (SMURF2) LDTP12138 0.71  LDD2097 
E3 ubiquitin/ISG15 ligase TRIM25 (TRIM25) LDTP06098 1.07  LDD2097 
Electron transfer flavoprotein subunit alpha, mitochondrial (ETFA) LDTP02694 0.71  LDD2097 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 1.01  LDD2097 
Elongation factor 2 (EEF2) LDTP02672 1.07; 1.01; 0.93 ...  LDD2097 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 1.04  LDD2097 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 0.73  LDD2097 
Enoyl-CoA delta isomerase 2 (ECI2) LDTP01245 1.12  LDD2097 
Ephrin type-A receptor 2 (EPHA2) LDTP03474 0.81  LDD2097 
Ephrin type-B receptor 2 (EPHB2) LDTP03477 1.02  LDD2097 
Epidermal growth factor receptor (EGFR) LDTP01785 0.81  LDD2097 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 0.69  LDD2097 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 0.60; 0.96; 0.65  LDD2097 
Eukaryotic translation initiation factor 2 subunit 3B (EIF2S3B) LDTP14895 1.01; 0.64; 1.00  LDD2097 
Eukaryotic translation initiation factor 3 subunit F (EIF3F) LDTP00246 0.79  LDD2097 
Eukaryotic translation initiation factor 5B (EIF5B) LDTP01063 0.95; 0.71; 0.90 ...  LDD2097 
Exosome complex component 10 (EXOSC10) LDTP05312 0.64  LDD2097 
Exosome complex component MTR3 (EXOSC6) LDTP07054 0.97  LDD2097 
Exosome complex component RRP42 (EXOSC7) LDTP06283 1.01  LDD2097 
Exosome complex component RRP43 (EXOSC8) LDTP10110 1.09; 2.12  LDD2097 
Exosome RNA helicase MTR4 (MTREX) LDTP03975 0.92  LDD2097 
FACT complex subunit SPT16 (SUPT16H) LDTP14109 0.59  LDD2097 
FAST kinase domain-containing protein 2, mitochondrial (FASTKD2) LDTP12862 3.27  LDD2097 
Fatty acid synthase (FASN) LDTP04243 0.65; 0.64  LDD2097 
Fumarylacetoacetase (FAH) LDTP02868 0.86  LDD2097 
Galactokinase (GALK1) LDTP04424 1.06  LDD2097 
Gamma-glutamylcyclotransferase (GGCT) LDTP01164 0.75  LDD2097 
GDP-fucose protein O-fucosyltransferase 1 (POFUT1) LDTP11905 0.79  LDD2097 
General transcription and DNA repair factor IIH helicase subunit XPD (ERCC2) LDTP02938 0.98  LDD2097 
Glucosamine 6-phosphate N-acetyltransferase (GNPNAT1) LDTP10264 0.97; 0.82; 0.58  LDD2097 
Glucoside xylosyltransferase 1 (GXYLT1) LDTP14932 0.89  LDD2097 
Glutaredoxin-1 (GLRX) LDTP03786 0.58  LDD2097 
Glutaryl-CoA dehydrogenase, mitochondrial (GCDH) LDTP09939 0.69  LDD2097 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 0.79  LDD2097 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 0.81; 1.00  LDD2097 
Glutathione S-transferase P (GSTP1) LDTP02333 0.50  LDD2097 
Glutathione synthetase (GSS) LDTP04200 0.63; 0.62  LDD2097 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 0.74; 0.66; 1.00  LDD2097 
Glycerol-3-phosphate phosphatase (PGP) LDTP00089 0.61  LDD2097 
Glycine--tRNA ligase (GARS1) LDTP03946 2.05; 1.23  LDD2097 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 0.60; 0.94  LDD2097 
Glycylpeptide N-tetradecanoyltransferase 1 (NMT1) LDTP03537 1.14  LDD2097 
GMP reductase 2 (GMPR2) LDTP13080 1.00  LDD2097 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 0.93  LDD2097 
GPI-anchor transamidase (PIGK) LDTP09835 0.98  LDD2097 
GTP-binding nuclear protein Ran (RAN) LDTP05007 1.01; 1.07  LDD2097 
H/ACA ribonucleoprotein complex subunit DKC1 (DKC1) LDTP01061 0.72  LDD2097 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 1.28  LDD2097 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 0.47  LDD2097 
Heme oxygenase 2 (HMOX2) LDTP03540 1.08; 1.29  LDD2097 
Hexokinase-1 (HK1) LDTP02991 1.31; 0.70; 0.89  LDD2097 
Histidine--tRNA ligase, cytoplasmic (HARS1) LDTP02602 0.68  LDD2097 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 1.03  LDD2097 
Histone deacetylase 1 (HDAC1) LDTP05918 0.74  LDD2097 
Histone-lysine N-methyltransferase EHMT2 (EHMT2) LDTP10517 0.79  LDD2097 
Histone-lysine N-methyltransferase SETD7 (SETD7) LDTP09543 1.34  LDD2097 
Hydroxyacid-oxoacid transhydrogenase, mitochondrial (ADHFE1) LDTP08567 0.70  LDD2097 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 0.76  LDD2097 
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL) LDTP03794 0.41  LDD2097 
Hydroxysteroid dehydrogenase-like protein 2 (HSDL2) LDTP07762 1.02; 1.01  LDD2097 
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) LDTP01782 0.87  LDD2097 
Inorganic pyrophosphatase 2, mitochondrial (PPA2) LDTP11842 0.98  LDD2097 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 1.03  LDD2097 
Inositol monophosphatase 1 (IMPA1) LDTP03470 0.94; 1.17  LDD2097 
Isoamyl acetate-hydrolyzing esterase 1 homolog (IAH1) LDTP17082 0.73  LDD2097 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 0.91  LDD2097 
Isopentenyl-diphosphate Delta-isomerase 1 (IDI1) LDTP06006 1.06  LDD2097 
Ketohexokinase (KHK) LDTP04340 0.92  LDD2097 
Ketosamine-3-kinase (FN3KRP) LDTP16025 0.61  LDD2097 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 0.69  LDD2097 
L-xylulose reductase (DCXR) LDTP08082 1.11  LDD2097 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 0.91  LDD2097 
Lon protease homolog, mitochondrial (LONP1) LDTP03817 0.95  LDD2097 
Low molecular weight phosphotyrosine protein phosphatase (ACP1) LDTP03289 0.68  LDD2097 
Lymphokine-activated killer T-cell-originated protein kinase (PBK) LDTP10500 1.08  LDD2097 
Lysine--tRNA ligase (KARS1) LDTP06294 0.92; 0.91  LDD2097 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 0.79  LDD2097 
Macrophage migration inhibitory factor (MIF) LDTP02713 0.93; 1.10  LDD2097 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 0.53; 0.94; 0.63  LDD2097 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 0.59; 0.89  LDD2097 
Matrix metalloproteinase-14 (MMP14) LDTP04352 1.00  LDD2097 
Methionine adenosyltransferase 2 subunit beta (MAT2B) LDTP12915 0.75  LDD2097 
Microsomal glutathione S-transferase 1 (MGST1) LDTP02506 0.76  LDD2097 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 0.95  LDD2097 
Mitochondrial-processing peptidase subunit beta (PMPCB) LDTP01220 0.80  LDD2097 
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) LDTP07651 0.89; 0.98; 0.86  LDD2097 
Multifunctional protein CAD (CAD) LDTP03401 0.99; 1.07; 1.17 ...  LDD2097 
MYG1 exonuclease (MYG1) LDTP12154 0.77  LDD2097 
Myosin-9 (MYH9) LDTP03764 0.85; 1.36; 1.16 ...  LDD2097 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 1.05; 0.69; 1.22  LDD2097 
N-alpha-acetyltransferase 25, NatB auxiliary subunit (NAA25) LDTP06262 1.31  LDD2097 
NAD kinase 2, mitochondrial (NADK2) LDTP06839 0.65  LDD2097 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 1.00  LDD2097 
NADH dehydrogenase 1 alpha subcomplex subunit 5 (NDUFA5) LDTP06614 1.46  LDD2097 
NADH dehydrogenase 1 alpha subcomplex subunit 8 (NDUFA8) LDTP04494 0.76  LDD2097 
NADH dehydrogenase flavoprotein 1, mitochondrial (NDUFV1) LDTP04317 1.13  LDD2097 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 0.89  LDD2097 
NADH dehydrogenase iron-sulfur protein 6, mitochondrial (NDUFS6) LDTP14493 0.94  LDD2097 
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (NDUFS1) LDTP03433 1.09  LDD2097 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 0.82  LDD2097 
Neurolysin, mitochondrial (NLN) LDTP11494 0.85  LDD2097 
Neutral alpha-glucosidase AB (GANAB) LDTP06192 0.78  LDD2097 
Nicotinate-nucleotide pyrophosphorylase [carboxylating] (QPRT) LDTP06346 1.00  LDD2097 
Nuclear pore complex protein Nup98-Nup96 (NUP98) LDTP04547 1.05; 1.00  LDD2097 
Nucleolar GTP-binding protein 2 (GNL2) LDTP05987 1.06  LDD2097 
Obg-like ATPase 1 (OLA1) LDTP12610 1.09  LDD2097 
Oligoribonuclease, mitochondrial (REXO2) LDTP13972 1.03  LDD2097 
Ornithine aminotransferase, mitochondrial (OAT) LDTP02021 1.28  LDD2097 
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (CPOX) LDTP03813 0.89; 1.03  LDD2097 
Parkinson disease protein 7 (PARK7) LDTP10878 0.89; 0.63  LDD2097 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 0.38; 0.91  LDD2097 
Peptidyl-prolyl cis-trans isomerase B (PPIB) LDTP03216 0.93  LDD2097 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 0.75  LDD2097 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 1.07; 1.12  LDD2097 
Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8) LDTP06104 0.57; 3.00  LDD2097 
Peptidyl-prolyl cis-trans isomerase-like 1 (PPIL1) LDTP13976 1.04  LDD2097 
Peptidyl-tRNA hydrolase 2, mitochondrial (PTRH2) LDTP13989 1.21  LDD2097 
Peroxiredoxin-1 (PRDX1) LDTP05503 0.77  LDD2097 
Peroxiredoxin-4 (PRDX4) LDTP05773 1.06  LDD2097 
Peroxiredoxin-6 (PRDX6) LDTP03510 0.77  LDD2097 
Peroxisomal acyl-coenzyme A oxidase 2 (ACOX2) LDTP10859 1.01  LDD2097 
Peroxisomal multifunctional enzyme type 2 (HSD17B4) LDTP04440 0.60  LDD2097 
Persulfide dioxygenase ETHE1, mitochondrial (ETHE1) LDTP01633 0.54  LDD2097 
Phenylalanine--tRNA ligase beta subunit (FARSB) LDTP12586 1.30  LDD2097 
Phosphoacetylglucosamine mutase (PGM3) LDTP01584 0.88  LDD2097 
Phosphoglucomutase-1 (PGM1) LDTP03818 0.90  LDD2097 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 0.90; 0.94  LDD2097 
Phospholipid scramblase 1 (PLSCR1) LDTP00558 0.65  LDD2097 
Platelet-activating factor acetylhydrolase IB subunit alpha1 (PAFAH1B3) LDTP06315 0.62  LDD2097 
Platelet-activating factor acetylhydrolase IB subunit alpha2 (PAFAH1B2) LDTP05078 0.95  LDD2097 
Poly [ADP-ribose] polymerase 1 (PARP1) LDTP02375 0.71  LDD2097 
Pre-mRNA-processing factor 19 (PRPF19) LDTP13623 0.93  LDD2097 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 0.91  LDD2097 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 0.93  LDD2097 
Probable ATP-dependent RNA helicase DDX17 (DDX17) LDTP09899 0.57; 0.71  LDD2097 
Probable ATP-dependent RNA helicase DDX23 (DDX23) LDTP11248 0.96  LDD2097 
Probable ATP-dependent RNA helicase DDX27 (DDX27) LDTP10358 1.90  LDD2097 
Probable ATP-dependent RNA helicase DDX47 (DDX47) LDTP11730 0.94  LDD2097 
Probable ATP-dependent RNA helicase DDX5 (DDX5) LDTP02924 1.04; 0.79  LDD2097 
Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (ALG8) LDTP11290 0.65  LDD2097 
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (USP9X) LDTP09961 1.40  LDD2097 
Procollagen C-endopeptidase enhancer 1 (PCOLCE) LDTP06318 0.88  LDD2097 
Proliferation-associated protein 2G4 (PA2G4) LDTP13750 0.94; 1.02  LDD2097 
Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB) LDTP02096 0.82  LDD2097 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 0.74  LDD2097 
Prostaglandin E synthase 3 (PTGES3) LDTP06338 0.78  LDD2097 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 0.46; 0.81  LDD2097 
Proteasome subunit alpha type-4 (PSMA4) LDTP03333 0.62  LDD2097 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 2.18  LDD2097 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 0.68  LDD2097 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 0.99; 0.97; 0.97  LDD2097 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 0.75; 0.72  LDD2097 
Proteasome subunit beta type-3 (PSMB3) LDTP04284 0.55  LDD2097 
Proteasome subunit beta type-7 (PSMB7) LDTP10862 0.82  LDD2097 
Protein arginine N-methyltransferase 1 (PRMT1) LDTP10997 1.16  LDD2097 
Protein disulfide-isomerase (P4HB) LDTP02188 0.93; 1.04  LDD2097 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 1.08; 1.02  LDD2097 
Protein kinase C iota type (PRKCI) LDTP03960 0.98  LDD2097 
Protein phosphatase 1G (PPM1G) LDTP00616 0.96  LDD2097 
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 1.06; 1.06; 0.92 ...  LDD2097 
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT1) LDTP03152 0.82  LDD2097 
Pterin-4-alpha-carbinolamine dehydratase (PCBD1) LDTP04925 0.94  LDD2097 
Purine nucleoside phosphorylase (PNP) LDTP01781 0.85  LDD2097 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 0.73; 0.61  LDD2097 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 1.23; 0.74  LDD2097 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 1.06  LDD2097 
Pyruvate kinase PKM (PKM) LDTP02733 0.69; 0.72; 1.14  LDD2097 
Quinone oxidoreductase (CRYZ) LDTP05551 0.89  LDD2097 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 0.96  LDD2097 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 0.76  LDD2097 
Ras-related C3 botulinum toxin substrate 2 (RAC2) LDTP02768 1.02; 1.05  LDD2097 
Ras-related protein Rab-14 (RAB14) LDTP04901 1.69  LDD2097 
Ras-related protein Rab-1A (RAB1A) LDTP05006 0.78  LDD2097 
Ras-related protein Rab-34 (RAB34) LDTP11535 1.83; 1.35  LDD2097 
Ras-related protein Rab-7a (RAB7A) LDTP04399 0.76  LDD2097 
Ras-related protein Rab-8A (RAB8A) LDTP04888 0.89  LDD2097 
Regucalcin (RGN) LDTP06401 1.01  LDD2097 
Replication factor C subunit 3 (RFC3) LDTP03911 0.90  LDD2097 
Retinol dehydrogenase 12 (RDH12) LDTP10634 1.03  LDD2097 
Rho-associated protein kinase 2 (ROCK2) LDTP01127 1.08  LDD2097 
Ribonuclease P protein subunit p30 (RPP30) LDTP05100 0.54  LDD2097 
Ribonucleases P/MRP protein subunit POP1 (POP1) LDTP10903 0.73  LDD2097 
Ribonucleoside-diphosphate reductase subunit M2 (RRM2) LDTP03592 0.62  LDD2097 
Ribose-5-phosphate isomerase (RPIA) LDTP04236 0.74  LDD2097 
Ribosomal RNA small subunit methyltransferase NEP1 (EMG1) LDTP09951 0.99  LDD2097 
RNA cytidine acetyltransferase (NAT10) LDTP11690 0.92  LDD2097 
RNA helicase aquarius (AQR) LDTP00946 0.81  LDD2097 
RNA N6-adenosine-methyltransferase METTL16 (METTL16) LDTP08317 0.96  LDD2097 
RNA-splicing ligase RtcB homolog (RTCB) LDTP13992 1.05  LDD2097 
rRNA 2'-O-methyltransferase fibrillarin (FBL) LDTP03155 1.03  LDD2097 
S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) LDTP00890 1.05  LDD2097 
S-adenosylmethionine synthase isoform type-2 (MAT2A) LDTP03577 0.91  LDD2097 
S-formylglutathione hydrolase (ESD) LDTP02521 0.98  LDD2097 
S-phase kinase-associated protein 1 (SKP1) LDTP05052 1.00; 0.84  LDD2097 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 0.72; 0.94; 1.55 ...  LDD2097 
Serine beta-lactamase-like protein LACTB, mitochondrial (LACTB) LDTP05183 0.90  LDD2097 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 0.81; 0.87  LDD2097 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 1.26; 1.27  LDD2097 
Serine palmitoyltransferase 2 (SPTLC2) LDTP00598 1.49  LDD2097 
Serine/threonine-protein kinase VRK1 (VRK1) LDTP11030 1.73  LDD2097 
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PPP2R2A) LDTP05046 0.84  LDD2097 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 0.66  LDD2097 
Serine/threonine-protein phosphatase PGAM5, mitochondrial (PGAM5) LDTP10399 0.70  LDD2097 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 1.22  LDD2097 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 1.72; 0.96; 1.31  LDD2097 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 0.75; 0.82; 1.42 ...  LDD2097 
Sorbitol dehydrogenase (SORD) LDTP05258 1.00  LDD2097 
Spermine synthase (SMS) LDTP04530 0.83  LDD2097 
Spliceosome RNA helicase DDX39B (DDX39B) LDTP05991 0.66; 0.73  LDD2097 
Sterol O-acyltransferase 1 (SOAT1) LDTP03769 1.07  LDD2097 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 0.77  LDD2097 
Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA) LDTP03572 0.96; 1.70  LDD2097 
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (SUCLG1) LDTP04566 0.87  LDD2097 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 0.84; 1.03  LDD2097 
SUMO-conjugating enzyme UBC9 (UBE2I) LDTP05062 0.70  LDD2097 
Thimet oligopeptidase (THOP1) LDTP04542 0.93; 0.92  LDD2097 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 1.35; 1.30; 1.22 ...  LDD2097 
Thioredoxin reductase 1, cytoplasmic (TXNRD1) LDTP06658 0.67  LDD2097 
Thymidylate kinase (DTYMK) LDTP03258 1.06  LDD2097 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 1.09; 0.68  LDD2097 
Transforming protein RhoA (RHOA) LDTP04927 1.18  LDD2097 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 0.82; 1.24; 0.91  LDD2097 
Translin (TSN) LDTP06427 0.80  LDD2097 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 0.76  LDD2097 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 0.98; 0.93; 0.72  LDD2097 
Triosephosphate isomerase (TPI1) LDTP04851 0.81; 1.40; 0.96 ...  LDD2097 
Tripeptidyl-peptidase 2 (TPP2) LDTP03469 1.07; 1.05  LDD2097 
TRMT1-like protein (TRMT1L) LDTP15236 1.26  LDD2097 
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (TRMT61A) LDTP10320 1.02; 0.81  LDD2097 
Tyrosine-protein phosphatase non-receptor type 23 (PTPN23) LDTP11887 0.74  LDD2097 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 1.01; 0.97; 1.34  LDD2097 
Ubiquitin carboxyl-terminal hydrolase 13 (USP13) LDTP09959 1.38  LDD2097 
Ubiquitin carboxyl-terminal hydrolase 5 (USP5) LDTP04074 0.81; 0.82  LDD2097 
Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 1.08  LDD2097 
Ubiquitin-conjugating enzyme E2 variant 1 (UBE2V1) LDTP05853 0.61  LDD2097 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 0.83; 0.97  LDD2097 
Ubiquitin-like modifier-activating enzyme 6 (UBA6) LDTP00013 0.85  LDD2097 
Ubiquitin-protein ligase E3A (UBE3A) LDTP05446 0.99  LDD2097 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 0.86; 0.65  LDD2097 
UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1) LDTP12851 0.70  LDD2097 
UDP-N-acetylhexosamine pyrophosphorylase (UAP1) LDTP06517 1.01  LDD2097 
UMP-CMP kinase (CMPK1) LDTP03519 0.78  LDD2097 
Uridine phosphorylase 1 (UPP1) LDTP06643 1.07  LDD2097 
Uroporphyrinogen decarboxylase (UROD) LDTP02135 0.60  LDD2097 
UTP--glucose-1-phosphate uridylyltransferase (UGP2) LDTP06649 0.91  LDD2097 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 1.59  LDD2097 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 0.59  LDD2097 
Vacuolar protein sorting-associated protein 4B (VPS4B) LDTP01186 0.80  LDD2097 
Very long chain fatty acid elongase 5 (ELOVL5) LDTP12841 0.78  LDD2097 
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) LDTP04289 0.73  LDD2097 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 0.75  LDD2097 
Vesicle-fusing ATPase (NSF) LDTP04096 1.10  LDD2097 
X-ray repair cross-complementing protein 5 (XRCC5) LDTP02642 0.74; 0.67  LDD2097 
X-ray repair cross-complementing protein 6 (XRCC6) LDTP02640 0.72  LDD2097 
Xaa-Pro aminopeptidase 1 (XPNPEP1) LDTP12444 0.83  LDD2097 
------------------------------------------------------------------------------------
⏷ Show the Full List of 377 Enzyme
118 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein gamma (YWHAG) LDTP04953 0.81  LDD2097 
14-3-3 protein theta (YWHAQ) LDTP03385 0.98; 0.99  LDD2097 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 0.90  LDD2097 
Annexin A1 (ANXA1) LDTP02010 1.71; 0.75  LDD2097 
Annexin A6 (ANXA6) LDTP02247 0.82; 0.60; 0.41  LDD2097 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 0.87  LDD2097 
AP-1 complex subunit mu-1 (AP1M1) LDTP11407 1.03  LDD2097 
AP-2 complex subunit alpha-1 (AP2A1) LDTP01673 0.85; 0.96; 1.05  LDD2097 
AP-2 complex subunit alpha-2 (AP2A2) LDTP01477 0.81  LDD2097 
AP-2 complex subunit beta (AP2B1) LDTP05038 0.76; 0.65; 0.79  LDD2097 
AP-3 complex subunit delta-1 (AP3D1) LDTP00383 1.01  LDD2097 
Apoptosis regulator BAX (BAX) LDTP05528 0.46  LDD2097 
ATP synthase subunit d, mitochondrial (ATP5PD) LDTP14509 0.83  LDD2097 
ATP synthase subunit gamma, mitochondrial (ATP5F1C) LDTP03810 0.95  LDD2097 
ATP-binding cassette sub-family F member 2 (ABCF2) LDTP18526 0.88; 1.10  LDD2097 
Calreticulin (CALR) LDTP03402 1.03  LDD2097 
Cation-independent mannose-6-phosphate receptor (IGF2R) LDTP02586 1.10  LDD2097 
CD151 antigen (CD151) LDTP04187 1.07  LDD2097 
CD44 antigen (CD44) LDTP02823 0.65; 0.68  LDD2097 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 0.84; 0.97  LDD2097 
Clathrin heavy chain 1 (CLTC) LDTP05252 0.78; 0.91; 0.74 ...  LDD2097 
Clathrin light chain B (CLTB) LDTP02353 0.83  LDD2097 
Copine-1 (CPNE1) LDTP10989 1.33  LDD2097 
Copine-3 (CPNE3) LDTP01133 0.52  LDD2097 
Cytochrome c oxidase subunit 5B, mitochondrial (COX5B) LDTP02504 1.74; 0.88  LDD2097 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 1.26  LDD2097 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) LDTP02057 0.83  LDD2097 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) LDTP02058 0.89  LDD2097 
Endoplasmic reticulum junction formation protein lunapark (LNPK) LDTP11609 1.39  LDD2097 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 1.02  LDD2097 
ER membrane protein complex subunit 8 (EMC8) LDTP00760 0.97  LDD2097 
Eukaryotic translation initiation factor 5A-1 (EIF5A) LDTP05056 0.85  LDD2097 
Exportin-1 (XPO1) LDTP00501 0.72  LDD2097 
Exportin-2 (CSE1L) LDTP04662 0.81; 0.95; 0.92 ...  LDD2097 
Fatty acid-binding protein 5 (FABP5) LDTP05292 1.10; 1.13; 0.64 ...  LDD2097 
Filamin-A (FLNA) LDTP03107 1.33; 0.62; 0.82 ...  LDD2097 
Filamin-B (FLNB) LDTP01197 0.77; 0.77; 1.08 ...  LDD2097 
Filamin-C (FLNC) LDTP06103 1.38; 0.99; 0.79 ...  LDD2097 
Galectin-3 (LGALS3) LDTP02929 0.95  LDD2097 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 0.66  LDD2097 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1) LDTP05017 1.05; 0.94  LDD2097 
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2) LDTP05020 1.14; 1.01; 1.09  LDD2097 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 1.24; 0.15  LDD2097 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 0.74  LDD2097 
Importin subunit alpha-7 (KPNA6) LDTP01031 0.59; 0.80  LDD2097 
Importin subunit beta-1 (KPNB1) LDTP06242 1.46  LDD2097 
Importin-4 (IPO4) LDTP09515 0.92; 1.00; 1.05 ...  LDD2097 
Importin-5 (IPO5) LDTP00266 1.05; 0.98; 0.84 ...  LDD2097 
Importin-7 (IPO7) LDTP01574 1.04; 1.00  LDD2097 
Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) LDTP06153 1.20  LDD2097 
Integrin alpha-6 (ITGA6) LDTP03211 1.45  LDD2097 
Integrin alpha-V (ITGAV) LDTP02166 0.75  LDD2097 
Integrin beta-1 (ITGB1) LDTP02122 0.84  LDD2097 
Kinesin-1 heavy chain (KIF5B) LDTP03664 0.65; 0.88  LDD2097 
LETM1 domain-containing protein LETM2, mitochondrial (LETM2) LDTP14898 0.82  LDD2097 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 1.13; 0.89  LDD2097 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 0.53  LDD2097 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 1.17  LDD2097 
Metaxin-1 (MTX1) LDTP05900 1.22  LDD2097 
MICOS complex subunit MIC10 (MICOS10) LDTP07191 0.53  LDD2097 
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1) LDTP13698 1.00; 0.88  LDD2097 
Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) LDTP05384 1.10  LDD2097 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 1.00  LDD2097 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 0.72; 0.60  LDD2097 
Myeloid-associated differentiation marker (MYADM) LDTP10806 1.13  LDD2097 
Myoferlin (MYOF) LDTP12916 0.47; 1.01; 0.94 ...  LDD2097 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 0.81  LDD2097 
Nuclear cap-binding protein subunit 1 (NCBP1) LDTP05591 0.91  LDD2097 
Nuclear pore complex protein Nup153 (NUP153) LDTP04309 0.88  LDD2097 
Nuclear pore complex protein Nup205 (NUP205) LDTP09825 1.18; 1.07; 1.01 ...  LDD2097 
Nuclear pore complex protein Nup85 (NUP85) LDTP11310 0.94  LDD2097 
Nuclear pore complex protein Nup88 (NUP88) LDTP10897 0.76  LDD2097 
Nucleoporin NDC1 (NDC1) LDTP11213 1.02  LDD2097 
Nucleoprotein TPR (TPR) LDTP02612 0.99  LDD2097 
Optineurin (OPTN) LDTP10189 0.81  LDD2097 
Podocalyxin (PODXL) LDTP00321 0.71; 1.26  LDD2097 
Prohibitin 1 (PHB1) LDTP03717 0.82  LDD2097 
Prosaposin (PSAP) LDTP02215 1.02; 0.92; 0.93  LDD2097 
Protein S100-A10 (S100A10) LDTP04885 0.61  LDD2097 
Protein transport protein Sec31A (SEC31A) LDTP01478 0.89  LDD2097 
Protein transport protein Sec61 subunit gamma (SEC61G) LDTP04850 1.06  LDD2097 
Ran GTPase-activating protein 1 (RANGAP1) LDTP04082 0.96  LDD2097 
Sideroflexin-4 (SFXN4) LDTP07531 0.40  LDD2097 
Signal recognition particle 14 kDa protein (SRP14) LDTP03837 0.69  LDD2097 
Signal recognition particle 9 kDa protein (SRP9) LDTP04259 0.83  LDD2097 
Signal recognition particle subunit SRP68 (SRP68) LDTP13262 1.05  LDD2097 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 0.93; 0.83; 1.12  LDD2097 
Sodium/potassium-transporting ATPase subunit beta-3 (ATP1B3) LDTP04624 1.17  LDD2097 
Solute carrier family 23 member 2 (SLC23A2) LDTP13224 1.00  LDD2097 
Solute carrier family 25 member 3 (SLC25A3) LDTP05238 0.85  LDD2097 
Sorting nexin-12 (SNX12) LDTP13634 0.90  LDD2097 
Sorting nexin-5 (SNX5) LDTP14174 0.86  LDD2097 
Spectrin beta chain, non-erythrocytic 1 (SPTBN1) LDTP05273 0.83  LDD2097 
T-complex protein 1 subunit delta (CCT4) LDTP04391 0.83; 0.99; 0.97  LDD2097 
Talin-1 (TLN1) LDTP14031 0.76; 0.95; 0.74 ...  LDD2097 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 0.98  LDD2097 
THO complex subunit 1 (THOC1) LDTP10317 0.93  LDD2097 
THO complex subunit 6 homolog (THOC6) LDTP08315 0.81  LDD2097 
Tissue factor (F3) LDTP02686 0.92  LDD2097 
Transferrin receptor protein 1 (TFRC) LDTP01969 0.85  LDD2097 
Translocation protein SEC62 (SEC62) LDTP15838 0.79; 1.00  LDD2097 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 1.10; 1.20  LDD2097 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 1.05  LDD2097 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 1.55  LDD2097 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 1.03  LDD2097 
Transmembrane protein 214 (TMEM214) LDTP07477 0.91  LDD2097 
Transmembrane protein 33 (TMEM33) LDTP04787 0.82  LDD2097 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 0.85  LDD2097 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 0.79; 1.13; 1.57 ...  LDD2097 
Vesicle-associated membrane protein-associated protein A (VAPA) LDTP12966 0.72; 0.89  LDD2097 
Vesicle-associated membrane protein-associated protein B/C (VAPB) LDTP01556 0.79  LDD2097 
Vesicular integral-membrane protein VIP36 (LMAN2) LDTP05690 1.01  LDD2097 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 0.64  LDD2097 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 0.93  LDD2097 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 1.04  LDD2097 
Zinc transporter 7 (SLC30A7) LDTP09180 1.11  LDD2097 
Zinc transporter ZIP10 (SLC39A10) LDTP13543 1.07  LDD2097 
Zinc transporter ZIP13 (SLC39A13) LDTP10375 0.95  LDD2097 
------------------------------------------------------------------------------------
⏷ Show the Full List of 118 Transporter and channel
15 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Chorion-specific transcription factor GCMb (GCM2) LDTP01270 0.89  LDD2097 
Dr1-associated corepressor (DRAP1) LDTP06229 1.02  LDD2097 
eIF5-mimic protein 1 (BZW2) LDTP14241 1.28  LDD2097 
FACT complex subunit SSRP1 (SSRP1) LDTP05577 1.12  LDD2097 
Fos-related antigen 1 (FOSL1) LDTP02786 0.94  LDD2097 
General transcription factor II-I (GTF2I) LDTP05101 0.84  LDD2097 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 0.68; 1.03  LDD2097 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 1.07; 0.84  LDD2097 
Nuclear autoantigen Sp-100 (SP100) LDTP03237 0.74  LDD2097 
Nuclear factor 1 C-type (NFIC) LDTP02296 0.52  LDD2097 
Nuclear factor of activated T-cells, cytoplasmic 4 (NFATC4) LDTP06231 1.01  LDD2097 
Recombining binding protein suppressor of hairless (RBPJ) LDTP05485 0.76  LDD2097 
Transcription factor A, mitochondrial (TFAM) LDTP05235 1.07  LDD2097 
Transcription factor MafF (MAFF) LDTP13593 1.31  LDD2097 
Transcriptional activator protein Pur-alpha (PURA) LDTP05248 0.95  LDD2097 
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⏷ Show the Full List of 15 Transcription factor
4 Immunoglobulin Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Basigin (BSG) LDTP03772 0.81  LDD2097 
Cell surface glycoprotein MUC18 (MCAM) LDTP04020 1.07  LDD2097 
Intercellular adhesion molecule 1 (ICAM1) LDTP02106 0.47  LDD2097 
Programmed cell death 1 ligand 1 (CD274) LDTP12930 1.06  LDD2097 
------------------------------------------------------------------------------------
1 Cytokine and receptor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Endoglin (ENG) LDTP02923 1.01; 0.89; 1.00  LDD2097 
------------------------------------------------------------------------------------
392 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein eta (YWHAH) LDTP05442 1.10  LDD2097 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 0.84; 1.94  LDD2097 
26S proteasome non-ATPase regulatory subunit 6 (PSMD6) LDTP06273 0.78  LDD2097 
60S ribosome subunit biogenesis protein NIP7 homolog (NIP7) LDTP13779 0.99; 0.80  LDD2097 
A-kinase anchor protein 1, mitochondrial (AKAP1) LDTP09837 1.23; 1.17  LDD2097 
Abnormal spindle-like microcephaly-associated protein (ASPM) LDTP08716 1.09  LDD2097 
Actin-like protein 6A (ACTL6A) LDTP01756 0.68  LDD2097 
Actin-related protein 2 (ACTR2) LDTP04903 0.95  LDD2097 
Actin-related protein 2/3 complex subunit 1B (ARPC1B) LDTP00550 0.80  LDD2097 
Actin-related protein 2/3 complex subunit 3 (ARPC3) LDTP00552 0.51  LDD2097 
Actin-related protein 3 (ACTR3) LDTP04902 1.14  LDD2097 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 1.18; 0.72; 0.80 ...  LDD2097 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 0.70  LDD2097 
Alpha-centractin (ACTR1A) LDTP04904 0.99  LDD2097 
Alpha-soluble NSF attachment protein (NAPA) LDTP04647 0.94; 0.98  LDD2097 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1) LDTP05687 0.39  LDD2097 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 0.98; 1.04  LDD2097 
Anillin (ANLN) LDTP12443 1.03; 0.80  LDD2097 
Annexin A4 (ANXA4) LDTP02354 0.64  LDD2097 
Armadillo repeat-containing protein 6 (ARMC6) LDTP15101 0.82; 0.89  LDD2097 
Astrocytic phosphoprotein PEA-15 (PEA15) LDTP06323 0.80  LDD2097 
Ataxin-2 (ATXN2) LDTP10947 1.16  LDD2097 
Atos homolog protein A (ATOSA) LDTP14902 1.07  LDD2097 
Band 4.1-like protein 2 (EPB41L2) LDTP00778 2.60  LDD2097 
Barrier-to-autointegration factor (BANF1) LDTP01250 0.74; 0.51  LDD2097 
BRCA2 and CDKN1A-interacting protein (BCCIP) LDTP13030 0.97  LDD2097 
BTB/POZ domain-containing protein KCTD5 (KCTD5) LDTP12791 0.98  LDD2097 
Calmegin (CLGN) LDTP00493 0.88  LDD2097 
Calponin-2 (CNN2) LDTP10864 0.87  LDD2097 
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) LDTP02511 0.71  LDD2097 
CAP-Gly domain-containing linker protein 1 (CLIP1) LDTP03553 0.73  LDD2097 
Caprin-1 (CAPRIN1) LDTP06121 0.66  LDD2097 
Catenin alpha-1 (CTNNA1) LDTP03711 0.79  LDD2097 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 1.60; 1.06; 1.00 ...  LDD2097 
CCN family member 1 (CCN1) LDTP00323 0.94; 1.95  LDD2097 
Cdc42 effector protein 2 (CDC42EP2) LDTP00382 1.42  LDD2097 
Centromere/kinetochore protein zw10 homolog (ZW10) LDTP00720 1.02; 1.00  LDD2097 
Charged multivesicular body protein 1a (CHMP1A) LDTP12285 0.71  LDD2097 
Charged multivesicular body protein 1b (CHMP1B) LDTP07984 0.95  LDD2097 
Cilia- and flagella-associated protein 20 (CFAP20) LDTP14227 0.72  LDD2097 
Cleavage and polyadenylation specificity factor subunit 6 (CPSF6) LDTP06584 0.78; 0.77  LDD2097 
Cleavage and polyadenylation specificity factor subunit 7 (CPSF7) LDTP08922 0.75; 0.67  LDD2097 
Cleavage stimulation factor subunit 2 (CSTF2) LDTP03665 0.97  LDD2097 
Cleavage stimulation factor subunit 2 tau variant (CSTF2T) LDTP11718 1.08  LDD2097 
Coactosin-like protein (COTL1) LDTP06024 0.74  LDD2097 
Coatomer subunit alpha (COPA) LDTP04571 0.77  LDD2097 
Coatomer subunit beta (COPB1) LDTP04570 1.82; 1.02; 1.38  LDD2097 
Coatomer subunit delta (ARCN1) LDTP04181 1.62; 0.93  LDD2097 
Cofilin-1 (CFL1) LDTP03244 0.98; 1.08; 0.72 ...  LDD2097 
Cofilin-2 (CFL2) LDTP13827 0.78  LDD2097 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 0.89  LDD2097 
Collagen alpha-2(IV) chain (COL4A2) LDTP02282 1.42  LDD2097 
Condensin complex subunit 1 (NCAPD2) LDTP06281 0.99  LDD2097 
Conserved oligomeric Golgi complex subunit 1 (COG1) LDTP09549 0.92  LDD2097 
Constitutive coactivator of PPAR-gamma-like protein 1 (FAM120A) LDTP12883 0.93; 1.15  LDD2097 
COP9 signalosome complex subunit 1 (GPS1) LDTP05746 1.03  LDD2097 
Copper transport protein ATOX1 (ATOX1) LDTP00229 1.04; 0.92  LDD2097 
Core histone macro-H2A.1 (MACROH2A1) LDTP01195 1.03  LDD2097 
Coronin-1B (CORO1B) LDTP11101 0.80  LDD2097 
Coronin-1C (CORO1C) LDTP13580 0.87; 0.77; 0.79 ...  LDD2097 
CUGBP Elav-like family member 1 (CELF1) LDTP09913 0.75  LDD2097 
Cysteine and histidine-rich domain-containing protein 1 (CHORDC1) LDTP13269 0.84  LDD2097 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 0.91; 0.95; 0.82 ...  LDD2097 
Cytoplasmic FMR1-interacting protein 1 (CYFIP1) LDTP07958 0.90  LDD2097 
Cytoskeleton-associated protein 5 (CKAP5) LDTP06021 0.84  LDD2097 
DAZ-associated protein 1 (DAZAP1) LDTP10271 0.72; 0.69  LDD2097 
Destrin (DSTN) LDTP04887 0.96; 0.91; 0.97 ...  LDD2097 
Disks large homolog 2 (DLG2) LDTP06448 0.93  LDD2097 
DNA damage-binding protein 1 (DDB1) LDTP06543 0.80  LDD2097 
DNA mismatch repair protein Msh6 (MSH6) LDTP04518 0.91; 0.74  LDD2097 
DnaJ homolog subfamily A member 2 (DNAJA2) LDTP01073 1.15; 0.91  LDD2097 
DnaJ homolog subfamily C member 3 (DNAJC3) LDTP05789 2.07  LDD2097 
DnaJ homolog subfamily C member 7 (DNAJC7) LDTP10920 0.93; 0.91  LDD2097 
Dynein axonemal assembly factor 5 (DNAAF5) LDTP08387 0.95  LDD2097 
Early endosome antigen 1 (EEA1) LDTP06310 0.75; 0.79  LDD2097 
Ectopic P granules protein 5 homolog (EPG5) LDTP12232 1.10  LDD2097 
ELAV-like protein 1 (ELAVL1) LDTP06450 0.56  LDD2097 
ELAV-like protein 2 (ELAVL2) LDTP14824 0.61  LDD2097 
Elongin-B (ELOB) LDTP06369 0.93  LDD2097 
Endoplasmin (HSP90B1) LDTP02734 0.51  LDD2097 
Engulfment and cell motility protein 1 (ELMO1) LDTP09794 1.41  LDD2097 
Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8L2) LDTP11998 1.02; 0.79  LDD2097 
Epsin-2 (EPN2) LDTP01527 0.69  LDD2097 
ERBB receptor feedback inhibitor 1 (ERRFI1) LDTP13388 1.22  LDD2097 
Eukaryotic peptide chain release factor subunit 1 (ETF1) LDTP04993 1.04  LDD2097 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 0.92; 0.86; 0.76 ...  LDD2097 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 1.11; 0.90  LDD2097 
Eukaryotic translation initiation factor 3 subunit B (EIF3B) LDTP04718 0.83; 0.93  LDD2097 
Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 1.03  LDD2097 
Eukaryotic translation initiation factor 3 subunit E (EIF3E) LDTP04853 1.10  LDD2097 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 1.52  LDD2097 
Eukaryotic translation initiation factor 3 subunit J (EIF3J) LDTP01320 0.78  LDD2097 
Eukaryotic translation initiation factor 3 subunit K (EIF3K) LDTP13143 0.94  LDD2097 
Eukaryotic translation initiation factor 3 subunit M (EIF3M) LDTP07947 0.55  LDD2097 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 0.90; 0.74  LDD2097 
Eukaryotic translation initiation factor 6 (EIF6) LDTP04743 0.56  LDD2097 
Exosome complex component RRP40 (EXOSC3) LDTP12434 0.73  LDD2097 
F-actin-capping protein subunit alpha-1 (CAPZA1) LDTP04544 0.62  LDD2097 
F-actin-capping protein subunit beta (CAPZB) LDTP04127 1.00  LDD2097 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 0.83; 0.83  LDD2097 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 0.60; 0.80  LDD2097 
Far upstream element-binding protein 3 (FUBP3) LDTP10408 0.76  LDD2097 
Follistatin-related protein 1 (FSTL1) LDTP05666 0.59  LDD2097 
Galectin-1 (LGALS1) LDTP02341 0.78; 1.00; 0.81  LDD2097 
Gem-associated protein 4 (GEMIN4) LDTP04790 1.02  LDD2097 
General transcription factor 3C polypeptide 5 (GTF3C5) LDTP14147 0.83  LDD2097 
Gephyrin (GPHN) LDTP12448 0.55; 0.70  LDD2097 
Golgi apparatus protein 1 (GLG1) LDTP09920 2.64; 1.00; 1.05  LDD2097 
Golgi SNAP receptor complex member 2 (GOSR2) LDTP00397 0.95  LDD2097 
GRIP and coiled-coil domain-containing protein 2 (GCC2) LDTP08543 0.83  LDD2097 
Growth factor receptor-bound protein 2 (GRB2) LDTP05035 0.79  LDD2097 
GrpE protein homolog 1, mitochondrial (GRPEL1) LDTP12144 0.57  LDD2097 
Guanine nucleotide-binding protein G(i) subunit alpha-2 (GNAI2) LDTP02059 1.31; 0.89  LDD2097 
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (GNG12) LDTP13120 1.04  LDD2097 
Heat shock 70 kDa protein 14 (HSPA14) LDTP14819 1.21  LDD2097 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 0.64; 0.88  LDD2097 
Heat shock protein 105 kDa (HSPH1) LDTP09811 0.71; 1.04; 0.91 ...  LDD2097 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 1.04  LDD2097 
Hepatoma-derived growth factor (HDGF) LDTP04483 0.68  LDD2097 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 1.04  LDD2097 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 1.11  LDD2097 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 1.26  LDD2097 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 0.90  LDD2097 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 0.97  LDD2097 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 0.98  LDD2097 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 1.27; 0.90; 0.86  LDD2097 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 1.14; 0.84; 1.19  LDD2097 
Heterogeneous nuclear ribonucleoprotein L (HNRNPL) LDTP02750 0.79  LDD2097 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 1.11; 0.76; 1.36  LDD2097 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 1.02  LDD2097 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 1.09; 0.86; 0.82  LDD2097 
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) LDTP11238 0.67  LDD2097 
Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) LDTP02227 0.88  LDD2097 
Hippocalcin-like protein 1 (HPCAL1) LDTP03841 0.87  LDD2097 
Histone-binding protein RBBP4 (RBBP4) LDTP05590 1.31  LDD2097 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 1.03  LDD2097 
Host cell factor 1 (HCFC1) LDTP04434 0.97; 0.65  LDD2097 
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) LDTP00272 0.74  LDD2097 
Integrin alpha-2 (ITGA2) LDTP02893 0.75  LDD2097 
Integrin alpha-3 (ITGA3) LDTP03342 2.44; 1.09; 1.03 ...  LDD2097 
Interferon-induced protein with tetratricopeptide repeats 5 (IFIT5) LDTP05828 1.45  LDD2097 
Interleukin enhancer-binding factor 3 (ILF3) LDTP05689 0.87; 0.49  LDD2097 
IST1 homolog (IST1) LDTP04593 0.86  LDD2097 
KAT8 regulatory NSL complex subunit 3 (KANSL3) LDTP13070 0.60  LDD2097 
KH domain-containing RNA-binding protein QKI (QKI) LDTP10700 0.59  LDD2097 
Kinectin (KTN1) LDTP08238 0.87  LDD2097 
La-related protein 4B (LARP4B) LDTP09820 0.69; 0.92  LDD2097 
Lamin-B1 (LMNB1) LDTP03065 0.68  LDD2097 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 0.82  LDD2097 
Large ribosomal subunit protein eL14 (RPL14) LDTP04389 0.65  LDD2097 
Large ribosomal subunit protein eL15 (RPL15) LDTP04919 1.13  LDD2097 
Large ribosomal subunit protein eL18 (RPL18) LDTP05509 0.97  LDD2097 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 0.44; 1.31  LDD2097 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 2.06  LDD2097 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 1.37  LDD2097 
Large ribosomal subunit protein eL30 (RPL30) LDTP05021 0.98; 0.82  LDD2097 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 1.36  LDD2097 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 0.95  LDD2097 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 1.09; 1.01; 0.70  LDD2097 
Large ribosomal subunit protein eL37 (RPL37) LDTP04943 0.80  LDD2097 
Large ribosomal subunit protein eL43 (RPL37A) LDTP04926 0.92; 1.44  LDD2097 
Large ribosomal subunit protein eL8 (RPL7A) LDTP04990 1.12; 0.83  LDD2097 
Large ribosomal subunit protein mL38 (MRPL38) LDTP10232 2.39  LDD2097 
Large ribosomal subunit protein mL43 (MRPL43) LDTP08994 0.70  LDD2097 
Large ribosomal subunit protein mL50 (MRPL50) LDTP15429 0.83; 0.71  LDD2097 
Large ribosomal subunit protein uL1 (RPL10A) LDTP05024 1.23; 0.96  LDD2097 
Large ribosomal subunit protein uL10 (RPLP0) LDTP02109 1.08  LDD2097 
Large ribosomal subunit protein uL11 (RPL12) LDTP03517 0.78; 0.87  LDD2097 
Large ribosomal subunit protein uL11m (MRPL11) LDTP13971 0.57  LDD2097 
Large ribosomal subunit protein uL3 (RPL3) LDTP03865 1.26; 0.92; 1.69 ...  LDD2097 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 1.04  LDD2097 
Large ribosomal subunit protein uL5 (RPL11) LDTP05026 1.16; 0.85  LDD2097 
Large ribosomal subunit protein uL6 (RPL9; RPL9P7; RPL9P8; RPL9P9) LDTP03658 0.83; 0.95  LDD2097 
LEM domain-containing protein 2 (LEMD2) LDTP09082 0.94  LDD2097 
Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) LDTP03997 1.05; 0.86; 0.92 ...  LDD2097 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 0.74; 1.00; 1.13 ...  LDD2097 
Malignant T-cell-amplified sequence 1 (MCTS1) LDTP13532 1.22  LDD2097 
Matrin-3 (MATR3) LDTP04027 0.64; 0.57  LDD2097 
Mediator of RNA polymerase II transcription subunit 11 (MED11) LDTP12955 0.70  LDD2097 
Mediator of RNA polymerase II transcription subunit 30 (MED30) LDTP10396 0.63  LDD2097 
Meiosis regulator and mRNA stability factor 1 (MARF1) LDTP14053 0.36  LDD2097 
Membralin (TMEM259) LDTP14939 0.84  LDD2097 
Membrane cofactor protein (CD46) LDTP02795 0.50  LDD2097 
Metallothionein-1X (MT1X) LDTP05159 1.81; 1.65  LDD2097 
Methylosome protein WDR77 (WDR77) LDTP11066 0.83  LDD2097 
MICOS complex subunit MIC19 (CHCHD3) LDTP12764 0.71; 1.04  LDD2097 
Microtubule-associated protein 4 (MAP4) LDTP03404 1.02; 1.08  LDD2097 
Mini-chromosome maintenance complex-binding protein (MCMBP) LDTP11197 1.02; 0.92  LDD2097 
Mitochondrial antiviral-signaling protein (MAVS) LDTP08058 0.62  LDD2097 
Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13) LDTP14136 0.77; 0.64  LDD2097 
Mitochondrial import inner membrane translocase subunit Tim21 (TIMM21) LDTP11304 1.16  LDD2097 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 1.48; 0.95  LDD2097 
Mitotic-spindle organizing protein 2A (MZT2A) LDTP15117 0.66  LDD2097 
MOB-like protein phocein (MOB4) LDTP13964 0.78  LDD2097 
Moesin (MSN) LDTP03346 0.77  LDD2097 
mRNA turnover protein 4 homolog (MRTO4) LDTP16220 1.02  LDD2097 
Mth938 domain-containing protein (AAMDC) LDTP16011 0.75  LDD2097 
Myb-binding protein 1A (MYBBP1A) LDTP11079 1.07; 0.96  LDD2097 
Myosin light polypeptide 6 (MYL6) LDTP04875 0.76  LDD2097 
Neuroblast differentiation-associated protein AHNAK (AHNAK) LDTP05597 0.84  LDD2097 
NHP2-like protein 1 (SNU13) LDTP04708 0.58; 0.62  LDD2097 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 0.86  LDD2097 
Nuclear mitotic apparatus protein 1 (NUMA1) LDTP06244 0.81; 1.91  LDD2097 
Nuclear receptor 2C2-associated protein (NR2C2AP) LDTP08338 0.97  LDD2097 
Nucleolar complex protein 2 homolog (NOC2L) LDTP14011 1.00  LDD2097 
Nucleolar protein 16 (NOP16) LDTP16278 0.79  LDD2097 
Nucleolar protein 56 (NOP56) LDTP00313 0.79  LDD2097 
Nucleolar protein 6 (NOL6) LDTP11993 0.82  LDD2097 
Nucleolin (NCL) LDTP02990 0.86  LDD2097 
Nucleolus and neural progenitor protein (NEPRO) LDTP15100 0.78  LDD2097 
Nucleophosmin (NPM1) LDTP02164 1.05  LDD2097 
OCIA domain-containing protein 2 (OCIAD2) LDTP17157 0.86; 1.10  LDD2097 
Opioid growth factor receptor (OGFR) LDTP16155 2.39  LDD2097 
Oxysterol-binding protein-related protein 11 (OSBPL11) LDTP11367 0.86  LDD2097 
Paxillin (PXN) LDTP04226 0.64  LDD2097 
PDZ and LIM domain protein 7 (PDLIM7) LDTP12461 0.98  LDD2097 
Perilipin-3 (PLIN3) LDTP01021 0.75  LDD2097 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 0.94  LDD2097 
Plastin-2 (LCP1) LDTP02691 0.74; 0.50; 0.60 ...  LDD2097 
Plectin (PLEC) LDTP06330 0.91; 0.45; 0.87 ...  LDD2097 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 1.02; 0.60  LDD2097 
Poly(rC)-binding protein 3 (PCBP3) LDTP04793 1.19; 0.63  LDD2097 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 0.86  LDD2097 
Polyadenylate-binding protein 1 (PABPC1) LDTP02595 0.66  LDD2097 
Pre-mRNA-processing-splicing factor 8 (PRPF8) LDTP07526 0.54; 0.89  LDD2097 
Pre-mRNA-splicing factor 38B (PRPF38B) LDTP17266 1.07  LDD2097 
Pre-mRNA-splicing factor ISY1 homolog (ISY1) LDTP13570 0.64  LDD2097 
Prefoldin subunit 5 (PFDN5) LDTP10873 0.60  LDD2097 
Prelamin-A/C (LMNA) LDTP01932 0.71  LDD2097 
Probable rRNA-processing protein EBP2 (EBNA1BP2) LDTP10993 0.82  LDD2097 
Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 1.93  LDD2097 
Proliferating cell nuclear antigen (PCNA) LDTP02596 0.87  LDD2097 
Proliferation marker protein Ki-67 (MKI67) LDTP04078 1.13; 0.79; 0.84 ...  LDD2097 
Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) LDTP08707 1.02  LDD2097 
Proline-rich AKT1 substrate 1 (AKT1S1) LDTP10111 1.19  LDD2097 
Proteasomal ubiquitin receptor ADRM1 (ADRM1) LDTP06514 0.79  LDD2097 
Proteasome activator complex subunit 1 (PSME1) LDTP05484 1.01; 0.65; 1.04  LDD2097 
Proteasome activator complex subunit 3 (PSME3) LDTP04917 0.75; 0.67  LDD2097 
Proteasome assembly chaperone 1 (PSMG1) LDTP01608 0.55  LDD2097 
Protein canopy homolog 2 (CNPY2) LDTP13841 0.95  LDD2097 
Protein Churchill (CHURC1) LDTP15622 1.21  LDD2097 
Protein FAM136A (FAM136A) LDTP18132 0.87  LDD2097 
Protein FAM3C (FAM3C) LDTP09773 0.67  LDD2097 
Protein flightless-1 homolog (FLII) LDTP05734 1.66; 0.65  LDD2097 
Protein HGH1 homolog (HGH1) LDTP18309 1.73; 0.75  LDD2097 
Protein IWS1 homolog (IWS1) LDTP10822 0.66  LDD2097 
Protein LSM12 (LSM12) LDTP06780 0.64  LDD2097 
Protein MEMO1 (MEMO1) LDTP13942 0.87  LDD2097 
Protein Niban 2 (NIBAN2) LDTP10847 0.74; 0.89; 2.19 ...  LDD2097 
Protein SAAL1 (SAAL1) LDTP18152 0.45  LDD2097 
Protein SGT1 homolog (SUGT1) LDTP13935 1.22  LDD2097 
Protein THEM6 (THEM6) LDTP19831 0.69; 0.84; 0.63  LDD2097 
Protein transport protein Sec24C (SEC24C) LDTP04594 0.82  LDD2097 
Protein unc-13 homolog D (UNC13D) LDTP07888 1.35  LDD2097 
Protein unc-45 homolog A (UNC45A) LDTP11890 0.95  LDD2097 
Putative protein FRMPD2-like (FRMPD2B) LDTP17342 0.79  LDD2097 
Putative RNA-binding protein Luc7-like 1 (LUC7L) LDTP12388 0.58  LDD2097 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 0.87; 0.99  LDD2097 
Rab GDP dissociation inhibitor alpha (GDI1) LDTP03574 1.03  LDD2097 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 0.90; 1.25  LDD2097 
Raftlin (RFTN1) LDTP06193 1.08  LDD2097 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 0.92; 1.03  LDD2097 
Rap1 GTPase-GDP dissociation stimulator 1 (RAP1GDS1) LDTP04504 0.99  LDD2097 
Ras GTPase-activating protein-binding protein 2 (G3BP2) LDTP13647 0.90  LDD2097 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 1.30; 0.99  LDD2097 
Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) LDTP07878 0.92  LDD2097 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 0.94  LDD2097 
Replication protein A 14 kDa subunit (RPA3) LDTP03723 0.37  LDD2097 
Replication protein A 32 kDa subunit (RPA2) LDTP02816 0.87  LDD2097 
Replication termination factor 2 (RTF2) LDTP11434 0.76  LDD2097 
Reticulon-4 (RTN4) LDTP12412 1.03  LDD2097 
Ribonuclease inhibitor (RNH1) LDTP02656 1.18; 1.18; 0.77  LDD2097 
Ribonucleoprotein PTB-binding 1 (RAVER1) LDTP15356 0.78  LDD2097 
Ribosomal L1 domain-containing protein 1 (RSL1D1) LDTP01379 0.86  LDD2097 
Ribosomal protein eL42-like (RPL36AL) LDTP15677 1.32  LDD2097 
Ribosomal protein eS27-like (RPS27L) LDTP07909 0.82  LDD2097 
Ribosomal protein uL16-like (RPL10L) LDTP10525 1.01; 0.88  LDD2097 
Ribosome biogenesis protein BOP1 (BOP1) LDTP06046 0.84  LDD2097 
Ribosome biogenesis protein BRX1 homolog (BRIX1) LDTP15609 0.77; 0.92  LDD2097 
Ribosome maturation protein SBDS (SBDS) LDTP13966 0.87; 0.91  LDD2097 
Ribosome-binding protein 1 (RRBP1) LDTP13044 1.03; 1.14; 0.92  LDD2097 
RNA transcription, translation and transport factor protein (RTRAF) LDTP13782 0.95  LDD2097 
RNA-binding motif, single-stranded-interacting protein 1 (RBMS1) LDTP03495 0.93; 0.64; 0.88  LDD2097 
RNA-binding protein 12B (RBM12B) LDTP17640 1.17  LDD2097 
RNA-binding protein 4 (RBM4) LDTP11324 0.68  LDD2097 
RNA-binding protein EWS (EWSR1) LDTP05318 0.72  LDD2097 
RNA-binding protein FUS (FUS) LDTP03775 0.83  LDD2097 
RNA-binding protein FXR1 (FXR1) LDTP04395 0.91; 0.98  LDD2097 
RNA-binding protein Raly (RALY) LDTP13467 0.93  LDD2097 
RRP12-like protein (RRP12) LDTP14980 0.73  LDD2097 
Scaffold attachment factor B2 (SAFB2) LDTP06054 0.93  LDD2097 
Sequestosome-1 (SQSTM1) LDTP05898 0.99  LDD2097 
Serine-threonine kinase receptor-associated protein (STRAP) LDTP13991 0.97  LDD2097 
Serine/arginine repetitive matrix protein 2 (SRRM2) LDTP13746 0.68; 0.69  LDD2097 
Serine/arginine-rich splicing factor 1 (SRSF1) LDTP05539 0.77  LDD2097 
Serine/arginine-rich splicing factor 3 (SRSF3) LDTP05197 3.28; 1.25; 1.41  LDD2097 
Serine/arginine-rich splicing factor 7 (SRSF7) LDTP06583 0.70  LDD2097 
Serine/threonine-protein phosphatase 6 regulatory subunit 1 (PPP6R1) LDTP13701 0.80  LDD2097 
Serine/threonine-protein phosphatase 6 regulatory subunit 3 (PPP6R3) LDTP06983 0.96; 2.17  LDD2097 
SERPINE1 mRNA-binding protein 1 (SERBP1) LDTP09081 1.02  LDD2097 
Serrate RNA effector molecule homolog (SRRT) LDTP11398 0.96  LDD2097 
SH3 domain-containing kinase-binding protein 1 (SH3KBP1) LDTP10117 0.91  LDD2097 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 0.93  LDD2097 
Sister chromatid cohesion protein PDS5 homolog A (PDS5A) LDTP06684 1.05  LDD2097 
Small nuclear ribonucleoprotein Sm D2 (SNRPD2) LDTP04982 1.11; 0.65  LDD2097 
Small nuclear ribonucleoprotein Sm D3 (SNRPD3) LDTP04983 0.84  LDD2097 
Small nuclear ribonucleoprotein-associated proteins B and B' (SNRPB) LDTP02741 0.47  LDD2097 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 2.13; 1.56; 1.28  LDD2097 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 4.53; 0.95; 1.07  LDD2097 
Small ribosomal subunit protein eS17 (RPS17) LDTP02302 0.81  LDD2097 
Small ribosomal subunit protein eS21 (RPS21) LDTP05055 0.98; 0.92  LDD2097 
Small ribosomal subunit protein eS25 (RPS25) LDTP05013 0.84  LDD2097 
Small ribosomal subunit protein eS26 (RPS26) LDTP05014 1.01  LDD2097 
Small ribosomal subunit protein eS28 (RPS28) LDTP05015 0.68  LDD2097 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 0.60  LDD2097 
Small ribosomal subunit protein eS6 (RPS6) LDTP05002 0.95  LDD2097 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 1.13  LDD2097 
Small ribosomal subunit protein mS27 (MRPS27) LDTP09793 0.60  LDD2097 
Small ribosomal subunit protein uS10 (RPS20) LDTP04880 0.74; 0.95  LDD2097 
Small ribosomal subunit protein uS2m (MRPS2) LDTP13961 1.90  LDD2097 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 1.01; 1.46  LDD2097 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 0.85  LDD2097 
Small ribosomal subunit protein uS8 (RPS15A) LDTP04965 1.09  LDD2097 
Small ribosomal subunit protein uS9 (RPS16) LDTP04966 0.80  LDD2097 
Small subunit processome component 20 homolog (UTP20) LDTP01294 1.39  LDD2097 
Small ubiquitin-related modifier 1 (SUMO1) LDTP05048 0.80  LDD2097 
Smoothelin (SMTN) LDTP04590 0.68  LDD2097 
SPATS2-like protein (SPATS2L) LDTP16102 0.74  LDD2097 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 1.14; 0.69; 0.66  LDD2097 
Splicing factor 1 (SF1) LDTP06429 0.92; 0.67  LDD2097 
Splicing factor 3B subunit 1 (SF3B1) LDTP01251 0.82; 0.54; 0.82  LDD2097 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 1.00  LDD2097 
Splicing factor 3B subunit 6 (SF3B6) LDTP13970 1.06  LDD2097 
Splicing factor 45 (RBM17) LDTP10409 0.70  LDD2097 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 2.88; 0.73  LDD2097 
Squamous cell carcinoma antigen recognized by T-cells 3 (SART3) LDTP06280 1.35  LDD2097 
SRA stem-loop-interacting RNA-binding protein, mitochondrial (SLIRP) LDTP11645 0.59  LDD2097 
Src substrate cortactin (CTTN) LDTP06094 1.22  LDD2097 
Stalled ribosome sensor GCN1 (GCN1) LDTP09821 0.96; 0.93  LDD2097 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 0.84; 0.79; 0.80  LDD2097 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 0.73; 0.75; 0.84 ...  LDD2097 
Striatin (STRN) LDTP00875 1.58  LDD2097 
Striatin-4 (STRN4) LDTP12519 1.33  LDD2097 
Stromal cell-derived factor 2 (SDF2) LDTP18279 0.71  LDD2097 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 0.63  LDD2097 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 0.81  LDD2097 
Structural maintenance of chromosomes protein 3 (SMC3) LDTP13760 1.02  LDD2097 
Structural maintenance of chromosomes protein 5 (SMC5) LDTP08618 2.01  LDD2097 
Syntaxin-7 (STX7) LDTP00632 0.83  LDD2097 
T-complex protein 1 subunit alpha (TCP1) LDTP02934 1.08; 0.83  LDD2097 
T-complex protein 1 subunit beta (CCT2) LDTP05113 1.42; 1.00  LDD2097 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 0.65; 0.78; 0.84 ...  LDD2097 
T-complex protein 1 subunit eta (CCT7) LDTP10990 0.74; 0.53; 0.71 ...  LDD2097 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 0.65; 0.93; 0.68 ...  LDD2097 
T-complex protein 1 subunit theta (CCT8) LDTP04390 0.85; 0.68; 0.99  LDD2097 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 0.82  LDD2097 
TAR DNA-binding protein 43 (TARDBP) LDTP05767 1.18  LDD2097 
Tetraspanin-4 (TSPAN4) LDTP00448 0.73  LDD2097 
THUMP domain-containing protein 1 (THUMPD1) LDTP12780 0.93; 0.71; 0.65  LDD2097 
Toll-interacting protein (TOLLIP) LDTP11702 1.57  LDD2097 
Transforming acidic coiled-coil-containing protein 1 (TACC1) LDTP01210 0.95  LDD2097 
Transforming acidic coiled-coil-containing protein 3 (TACC3) LDTP14228 1.29; 1.08  LDD2097 
Transgelin-2 (TAGLN2) LDTP03846 0.69  LDD2097 
Translationally-controlled tumor protein (TPT1) LDTP02683 0.98  LDD2097 
Transmembrane protein 161A (TMEM161A) LDTP12762 1.03  LDD2097 
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (TRMT6) LDTP13381 0.82  LDD2097 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 1.01  LDD2097 
Tubulin beta-6 chain (TUBB6) LDTP11233 1.08  LDD2097 
Tubulin-folding cofactor B (TBCB) LDTP10860 1.03; 0.64  LDD2097 
Tubulin-specific chaperone A (TBCA) LDTP01184 0.67  LDD2097 
Tumor protein D54 (TPD52L2) LDTP00759 0.92  LDD2097 
Twinfilin-2 (TWF2) LDTP07404 0.96; 0.89  LDD2097 
U1 small nuclear ribonucleoprotein C (SNRPC) LDTP02335 0.88  LDD2097 
U2 snRNP-associated SURP motif-containing protein (U2SURP) LDTP00517 0.63  LDD2097 
U6 snRNA-associated Sm-like protein LSm7 (LSM7) LDTP13425 0.56  LDD2097 
Ubiquitin-like protein 5 (UBL5) LDTP11545 0.77  LDD2097 
Urokinase plasminogen activator surface receptor (PLAUR) LDTP05404 1.79; 0.74  LDD2097 
Vacuolar fusion protein MON1 homolog B (MON1B) LDTP15214 0.81  LDD2097 
Vacuolar protein sorting-associated protein VTA1 homolog (VTA1) LDTP12317 0.95  LDD2097 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 0.50  LDD2097 
Vigilin (HDLBP) LDTP05239 1.00; 0.92; 1.09  LDD2097 
Vimentin (VIM) LDTP02297 0.94  LDD2097 
Vinculin (VCL) LDTP02946 0.75; 0.70; 0.74 ...  LDD2097 
WD repeat-containing protein 1 (WDR1) LDTP01118 0.94; 0.88  LDD2097 
WD repeat-containing protein 43 (WDR43) LDTP06305 0.64  LDD2097 
WD40 repeat-containing protein SMU1 (SMU1) LDTP06726 1.03; 1.13; 0.91 ...  LDD2097 
Wings apart-like protein homolog (WAPL) LDTP08094 1.08  LDD2097 
WW domain-containing adapter protein with coiled-coil (WAC) LDTP11191 0.82  LDD2097 
Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) LDTP08018 1.44; 0.92  LDD2097 
Zinc finger CCCH-type antiviral protein 1-like (ZC3HAV1L) LDTP18166 0.37  LDD2097 
Zinc finger RNA-binding protein (ZFR) LDTP15762 1.00; 0.74  LDD2097 
Zyxin (ZYX) LDTP06507 0.67; 1.21  LDD2097 
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Full Information of The Labelling Profiles of This Competitor

Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 5 mM
Quantitative Method Isotope tag
Experimemt Name ISO-TOP ABPP
Competitor Name Nucleophilic fragment 15a
Competitor Concentration 0.5 mM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cell lysate (MDA-MB-231)
Interaction Atlas ID  LDD2097  Download The Altas

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761