Details of the Target

General Information of Target

Target ID LDTP15117
Target Name Mitotic-spindle organizing protein 2A (MZT2A)
Gene Name MZT2A
Gene ID 653784
Synonyms
FAM128A; MOZART2A; Mitotic-spindle organizing protein 2A; Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN
VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR
VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN
RTPSITPQEERIAQLSESPVILTPNAKRTLPVDSSHGFSSKKRKSIKHNFNFELLPSNLF
NSSSTPVSVHIDTSSEGSSQSSLSPVLIGGNHLITAGVPRRSKRIAGKKVCRVESGKAGC
FSPKISHKEKVRRSLRLKFNLGKNGREVNGCSGVNRYESVGWRLANQQSLKNRIESVKTG
LLFSPDVDEKLPKKGSEKISKSEETLLTPERLVGTNYRMSWTGPNNSSFQEVDANEASSM
VENLEVENSLEPDIMVEKSPATSCELTPSNLNNKHNSNITSSPLSGDENNMTKETLVKVQ
KAFSESGSNLHALMNQRQSSVTNVGKVKLTEPSYLEDSPEENLFETNDLTIVESKEKYEH
HTGKGEKCFSERDFSPLQTQTFNRETTIKCYSTQMKMEHEKDIHSNMPKDYLSKQEFSSD
EEIKKQQSPKDKLNNKLKENENMMEGNLPKCAAHSKDEARSSFSQQSTCVVTNLSKPRPM
RIAKQQSLETCEKTVSESSQMTEHRKVSDHIQWFNKLSLNEPNRIKVKSPLKFQRTPVRQ
SVRRINSLLEYSRQPTGHKLASLGDTASPLVKSVSCDGALSSCIESASKDSSVSCIKSGP
KEQKSMSCEESNIGAISKSSMELPSKSFLKMRKHPDSVNASLRSTTVYKQKILSDGQVKV
PLDDLTNHDIVKPVVNNNMGISSGINNRVLRRPSERGRAWYKGSPKHPIGKTQLLPTSKP
VDL
Target Bioclass
Other
Family
MOZART2 family
Subcellular location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Uniprot ID
Q6P582
Ensemble ID
ENST00000309451.7
HGNC ID
HGNC:33187

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 6 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		N.A.  LDD0241  [1]
m-APA
 Probe Info  		13.90  LDD0403  [2]
BTD
 Probe Info  		C80(0.66)  LDD2097  [3]
IA-alkyne
 Probe Info  		C80(2.60)  LDD2190  [4]
DBIA
 Probe Info  		C80(1.15)  LDD0532  [5]
5E-2FA
 Probe Info  		N.A.  LDD2235  [6]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C80(3.87)  LDD0812  [5]
 LDCM0215  AC10 HCT 116 C80(1.15)  LDD0532  [5]
 LDCM0216  AC100 HEK-293T C80(1.04)  LDD0814  [5]
 LDCM0217  AC101 HEK-293T C80(0.94)  LDD0815  [5]
 LDCM0218  AC102 HEK-293T C80(1.00)  LDD0816  [5]
 LDCM0219  AC103 HEK-293T C80(1.11)  LDD0817  [5]
 LDCM0220  AC104 HEK-293T C80(0.83)  LDD0818  [5]
 LDCM0221  AC105 HEK-293T C80(0.97)  LDD0819  [5]
 LDCM0222  AC106 HEK-293T C80(0.84)  LDD0820  [5]
 LDCM0223  AC107 HEK-293T C80(0.95)  LDD0821  [5]
 LDCM0224  AC108 HEK-293T C80(0.84)  LDD0822  [5]
 LDCM0225  AC109 HEK-293T C80(0.99)  LDD0823  [5]
 LDCM0226  AC11 HCT 116 C80(1.06)  LDD0543  [5]
 LDCM0227  AC110 HEK-293T C80(1.00)  LDD0825  [5]
 LDCM0228  AC111 HEK-293T C80(1.00)  LDD0826  [5]
 LDCM0229  AC112 HEK-293T C80(0.84)  LDD0827  [5]
 LDCM0237  AC12 HCT 116 C80(0.98)  LDD0554  [5]
 LDCM0246  AC128 HEK-293T C80(1.69)  LDD0844  [5]
 LDCM0247  AC129 HEK-293T C80(1.79)  LDD0845  [5]
 LDCM0249  AC130 HEK-293T C80(1.59)  LDD0847  [5]
 LDCM0250  AC131 HEK-293T C80(1.45)  LDD0848  [5]
 LDCM0251  AC132 HEK-293T C80(1.55)  LDD0849  [5]
 LDCM0252  AC133 HEK-293T C80(1.30)  LDD0850  [5]
 LDCM0253  AC134 HEK-293T C80(1.69)  LDD0851  [5]
 LDCM0254  AC135 HEK-293T C80(1.26)  LDD0852  [5]
 LDCM0255  AC136 HEK-293T C80(1.22)  LDD0853  [5]
 LDCM0256  AC137 HEK-293T C80(1.31)  LDD0854  [5]
 LDCM0257  AC138 HEK-293T C80(1.31)  LDD0855  [5]
 LDCM0258  AC139 HEK-293T C80(1.29)  LDD0856  [5]
 LDCM0259  AC14 HCT 116 C80(0.90)  LDD0576  [5]
 LDCM0260  AC140 HEK-293T C80(1.29)  LDD0858  [5]
 LDCM0261  AC141 HEK-293T C80(1.03)  LDD0859  [5]
 LDCM0262  AC142 HEK-293T C80(1.09)  LDD0860  [5]
 LDCM0263  AC143 HEK-293T C80(0.90)  LDD0861  [5]
 LDCM0264  AC144 HEK-293T C80(0.85)  LDD0862  [5]
 LDCM0265  AC145 HEK-293T C80(0.90)  LDD0863  [5]
 LDCM0266  AC146 HEK-293T C80(0.97)  LDD0864  [5]
 LDCM0267  AC147 HEK-293T C80(0.83)  LDD0865  [5]
 LDCM0268  AC148 HEK-293T C80(0.84)  LDD0866  [5]
 LDCM0269  AC149 HEK-293T C80(0.90)  LDD0867  [5]
 LDCM0270  AC15 HCT 116 C80(0.89)  LDD0587  [5]
 LDCM0271  AC150 HEK-293T C80(0.77)  LDD0869  [5]
 LDCM0272  AC151 HEK-293T C80(0.80)  LDD0870  [5]
 LDCM0273  AC152 HEK-293T C80(0.80)  LDD0871  [5]
 LDCM0274  AC153 HEK-293T C80(0.76)  LDD0872  [5]
 LDCM0621  AC154 HEK-293T C80(0.86)  LDD2162  [5]
 LDCM0622  AC155 HEK-293T C80(0.86)  LDD2163  [5]
 LDCM0623  AC156 HEK-293T C80(0.87)  LDD2164  [5]
 LDCM0624  AC157 HEK-293T C80(0.92)  LDD2165  [5]
 LDCM0276  AC17 HCT 116 C80(1.28)  LDD0593  [5]
 LDCM0277  AC18 HCT 116 C80(1.06)  LDD0594  [5]
 LDCM0278  AC19 HCT 116 C80(1.41)  LDD0595  [5]
 LDCM0279  AC2 HEK-293T C80(1.49)  LDD0877  [5]
 LDCM0280  AC20 HCT 116 C80(1.72)  LDD0597  [5]
 LDCM0281  AC21 HCT 116 C80(1.25)  LDD0598  [5]
 LDCM0282  AC22 HCT 116 C80(1.48)  LDD0599  [5]
 LDCM0283  AC23 HCT 116 C80(1.06)  LDD0600  [5]
 LDCM0284  AC24 HCT 116 C80(1.20)  LDD0601  [5]
 LDCM0285  AC25 HEK-293T C80(1.50)  LDD0883  [5]
 LDCM0286  AC26 HEK-293T C80(1.69)  LDD0884  [5]
 LDCM0287  AC27 HEK-293T C80(1.61)  LDD0885  [5]
 LDCM0288  AC28 HEK-293T C80(1.44)  LDD0886  [5]
 LDCM0289  AC29 HEK-293T C80(1.45)  LDD0887  [5]
 LDCM0290  AC3 HEK-293T C80(1.06)  LDD0888  [5]
 LDCM0291  AC30 HEK-293T C80(1.61)  LDD0889  [5]
 LDCM0292  AC31 HEK-293T C80(1.16)  LDD0890  [5]
 LDCM0293  AC32 HEK-293T C80(1.48)  LDD0891  [5]
 LDCM0294  AC33 HEK-293T C80(1.46)  LDD0892  [5]
 LDCM0295  AC34 HEK-293T C80(1.45)  LDD0893  [5]
 LDCM0296  AC35 HCT 116 C80(0.83)  LDD0613  [5]
 LDCM0297  AC36 HCT 116 C80(0.87)  LDD0614  [5]
 LDCM0298  AC37 HCT 116 C80(0.97)  LDD0615  [5]
 LDCM0299  AC38 HCT 116 C80(1.13)  LDD0616  [5]
 LDCM0300  AC39 HCT 116 C80(1.07)  LDD0617  [5]
 LDCM0301  AC4 HEK-293T C80(1.02)  LDD0899  [5]
 LDCM0302  AC40 HCT 116 C80(0.81)  LDD0619  [5]
 LDCM0303  AC41 HCT 116 C80(0.93)  LDD0620  [5]
 LDCM0304  AC42 HCT 116 C80(1.02)  LDD0621  [5]
 LDCM0305  AC43 HCT 116 C80(0.87)  LDD0622  [5]
 LDCM0306  AC44 HCT 116 C80(1.00)  LDD0623  [5]
 LDCM0307  AC45 HCT 116 C80(1.04)  LDD0624  [5]
 LDCM0308  AC46 HEK-293T C80(0.93)  LDD0906  [5]
 LDCM0309  AC47 HEK-293T C80(0.87)  LDD0907  [5]
 LDCM0310  AC48 HEK-293T C80(0.94)  LDD0908  [5]
 LDCM0311  AC49 HEK-293T C80(0.95)  LDD0909  [5]
 LDCM0312  AC5 HEK-293T C80(1.05)  LDD0910  [5]
 LDCM0313  AC50 HEK-293T C80(0.94)  LDD0911  [5]
 LDCM0314  AC51 HEK-293T C80(1.01)  LDD0912  [5]
 LDCM0315  AC52 HEK-293T C80(0.96)  LDD0913  [5]
 LDCM0316  AC53 HEK-293T C80(0.89)  LDD0914  [5]
 LDCM0317  AC54 HEK-293T C80(0.94)  LDD0915  [5]
 LDCM0318  AC55 HEK-293T C80(0.88)  LDD0916  [5]
 LDCM0319  AC56 HEK-293T C80(0.82)  LDD0917  [5]
 LDCM0320  AC57 HEK-293T C80(0.89)  LDD0918  [5]
 LDCM0321  AC58 HEK-293T C80(1.45)  LDD0919  [5]
 LDCM0322  AC59 HEK-293T C80(1.02)  LDD0920  [5]
 LDCM0323  AC6 HCT 116 C80(0.93)  LDD0640  [5]
 LDCM0324  AC60 HEK-293T C80(1.13)  LDD0922  [5]
 LDCM0325  AC61 HEK-293T C80(1.00)  LDD0923  [5]
 LDCM0326  AC62 HEK-293T C80(0.84)  LDD0924  [5]
 LDCM0327  AC63 HEK-293T C80(0.95)  LDD0925  [5]
 LDCM0328  AC64 HEK-293T C80(0.89)  LDD0926  [5]
 LDCM0329  AC65 HEK-293T C80(0.89)  LDD0927  [5]
 LDCM0330  AC66 HEK-293T C80(0.92)  LDD0928  [5]
 LDCM0331  AC67 HEK-293T C80(0.75)  LDD0929  [5]
 LDCM0332  AC68 HEK-293T C80(1.03)  LDD0930  [5]
 LDCM0333  AC69 HEK-293T C80(1.05)  LDD0931  [5]
 LDCM0334  AC7 HCT 116 C80(0.84)  LDD0651  [5]
 LDCM0335  AC70 HEK-293T C80(1.06)  LDD0933  [5]
 LDCM0336  AC71 HEK-293T C80(1.00)  LDD0934  [5]
 LDCM0337  AC72 HEK-293T C80(1.08)  LDD0935  [5]
 LDCM0338  AC73 HEK-293T C80(0.98)  LDD0936  [5]
 LDCM0339  AC74 HEK-293T C80(1.06)  LDD0937  [5]
 LDCM0340  AC75 HEK-293T C80(0.96)  LDD0938  [5]
 LDCM0341  AC76 HEK-293T C80(0.96)  LDD0939  [5]
 LDCM0342  AC77 HEK-293T C80(1.05)  LDD0940  [5]
 LDCM0343  AC78 HEK-293T C80(1.26)  LDD0941  [5]
 LDCM0344  AC79 HEK-293T C80(1.13)  LDD0942  [5]
 LDCM0345  AC8 HCT 116 C80(0.88)  LDD0662  [5]
 LDCM0346  AC80 HEK-293T C80(1.19)  LDD0944  [5]
 LDCM0347  AC81 HEK-293T C80(1.10)  LDD0945  [5]
 LDCM0348  AC82 HEK-293T C80(1.40)  LDD0946  [5]
 LDCM0349  AC83 HCT 116 C80(1.26)  LDD0666  [5]
 LDCM0350  AC84 HCT 116 C80(0.99)  LDD0667  [5]
 LDCM0351  AC85 HCT 116 C80(0.96)  LDD0668  [5]
 LDCM0352  AC86 HCT 116 C80(0.84)  LDD0669  [5]
 LDCM0353  AC87 HCT 116 C80(1.16)  LDD0670  [5]
 LDCM0354  AC88 HCT 116 C80(0.97)  LDD0671  [5]
 LDCM0355  AC89 HCT 116 C80(1.32)  LDD0672  [5]
 LDCM0357  AC90 HCT 116 C80(1.54)  LDD0674  [5]
 LDCM0358  AC91 HCT 116 C80(1.09)  LDD0675  [5]
 LDCM0359  AC92 HCT 116 C80(1.19)  LDD0676  [5]
 LDCM0360  AC93 HCT 116 C80(0.95)  LDD0677  [5]
 LDCM0361  AC94 HCT 116 C80(1.13)  LDD0678  [5]
 LDCM0362  AC95 HCT 116 C80(0.97)  LDD0679  [5]
 LDCM0363  AC96 HCT 116 C80(1.24)  LDD0680  [5]
 LDCM0364  AC97 HCT 116 C80(1.28)  LDD0681  [5]
 LDCM0365  AC98 HEK-293T C80(1.20)  LDD0963  [5]
 LDCM0366  AC99 HEK-293T C80(1.31)  LDD0964  [5]
 LDCM0520  AKOS000195272 MDA-MB-231 C80(0.62)  LDD2113  [3]
 LDCM0248  AKOS034007472 HCT 116 C80(0.99)  LDD0565  [5]
 LDCM0356  AKOS034007680 HCT 116 C80(1.05)  LDD0673  [5]
 LDCM0275  AKOS034007705 HCT 116 C80(0.85)  LDD0592  [5]
 LDCM0156  Aniline NCI-H1299 13.90  LDD0403  [2]
 LDCM0367  CL1 HCT 116 C80(1.04)  LDD0684  [5]
 LDCM0368  CL10 HCT 116 C80(0.88)  LDD0685  [5]
 LDCM0369  CL100 HEK-293T C80(1.50)  LDD0967  [5]
 LDCM0370  CL101 HCT 116 C80(1.03)  LDD0687  [5]
 LDCM0371  CL102 HCT 116 C80(1.02)  LDD0688  [5]
 LDCM0372  CL103 HCT 116 C80(1.14)  LDD0689  [5]
 LDCM0373  CL104 HCT 116 C80(1.01)  LDD0690  [5]
 LDCM0374  CL105 HCT 116 C80(1.22)  LDD0691  [5]
 LDCM0375  CL106 HCT 116 C80(1.05)  LDD0692  [5]
 LDCM0376  CL107 HCT 116 C80(1.43)  LDD0693  [5]
 LDCM0377  CL108 HCT 116 C80(1.36)  LDD0694  [5]
 LDCM0378  CL109 HCT 116 C80(1.17)  LDD0695  [5]
 LDCM0379  CL11 HCT 116 C80(0.93)  LDD0696  [5]
 LDCM0380  CL110 HCT 116 C80(1.69)  LDD0697  [5]
 LDCM0381  CL111 HCT 116 C80(1.54)  LDD0698  [5]
 LDCM0382  CL112 HEK-293T C80(1.37)  LDD0980  [5]
 LDCM0383  CL113 HEK-293T C80(1.20)  LDD0981  [5]
 LDCM0384  CL114 HEK-293T C80(1.84)  LDD0982  [5]
 LDCM0385  CL115 HEK-293T C80(1.50)  LDD0983  [5]
 LDCM0386  CL116 HEK-293T C80(1.64)  LDD0984  [5]
 LDCM0387  CL117 HCT 116 C80(0.88)  LDD0704  [5]
 LDCM0388  CL118 HCT 116 C80(0.95)  LDD0705  [5]
 LDCM0389  CL119 HCT 116 C80(0.96)  LDD0706  [5]
 LDCM0390  CL12 HCT 116 C80(0.94)  LDD0707  [5]
 LDCM0391  CL120 HCT 116 C80(0.91)  LDD0708  [5]
 LDCM0392  CL121 HEK-293T C80(0.96)  LDD0990  [5]
 LDCM0393  CL122 HEK-293T C80(0.98)  LDD0991  [5]
 LDCM0394  CL123 HEK-293T C80(0.77)  LDD0992  [5]
 LDCM0395  CL124 HEK-293T C80(0.91)  LDD0993  [5]
 LDCM0396  CL125 HEK-293T C80(1.22)  LDD0994  [5]
 LDCM0397  CL126 HEK-293T C80(1.13)  LDD0995  [5]
 LDCM0398  CL127 HEK-293T C80(0.99)  LDD0996  [5]
 LDCM0399  CL128 HEK-293T C80(1.02)  LDD0997  [5]
 LDCM0400  CL13 HCT 116 C80(0.98)  LDD0717  [5]
 LDCM0401  CL14 HCT 116 C80(1.00)  LDD0718  [5]
 LDCM0402  CL15 HCT 116 C80(1.00)  LDD0719  [5]
 LDCM0403  CL16 HCT 116 C80(1.04)  LDD0720  [5]
 LDCM0404  CL17 HCT 116 C80(0.90)  LDD0721  [5]
 LDCM0405  CL18 HCT 116 C80(1.19)  LDD0722  [5]
 LDCM0406  CL19 HCT 116 C80(1.04)  LDD0723  [5]
 LDCM0407  CL2 HCT 116 C80(0.98)  LDD0724  [5]
 LDCM0408  CL20 HCT 116 C80(0.93)  LDD0725  [5]
 LDCM0409  CL21 HCT 116 C80(1.03)  LDD0726  [5]
 LDCM0410  CL22 HCT 116 C80(1.18)  LDD0727  [5]
 LDCM0411  CL23 HCT 116 C80(0.80)  LDD0728  [5]
 LDCM0412  CL24 HCT 116 C80(0.92)  LDD0729  [5]
 LDCM0413  CL25 HCT 116 C80(0.76)  LDD0730  [5]
 LDCM0414  CL26 HCT 116 C80(0.72)  LDD0731  [5]
 LDCM0415  CL27 HCT 116 C80(0.77)  LDD0732  [5]
 LDCM0416  CL28 HCT 116 C80(0.95)  LDD0733  [5]
 LDCM0417  CL29 HCT 116 C80(1.02)  LDD0734  [5]
 LDCM0418  CL3 HCT 116 C80(0.92)  LDD0735  [5]
 LDCM0419  CL30 HCT 116 C80(0.84)  LDD0736  [5]
 LDCM0420  CL31 HCT 116 C80(1.58)  LDD0737  [5]
 LDCM0421  CL32 HCT 116 C80(1.85)  LDD0738  [5]
 LDCM0422  CL33 HCT 116 C80(1.32)  LDD0739  [5]
 LDCM0423  CL34 HCT 116 C80(1.06)  LDD0740  [5]
 LDCM0424  CL35 HCT 116 C80(1.51)  LDD0741  [5]
 LDCM0425  CL36 HCT 116 C80(0.97)  LDD0742  [5]
 LDCM0426  CL37 HCT 116 C80(1.20)  LDD0743  [5]
 LDCM0428  CL39 HCT 116 C80(1.26)  LDD0745  [5]
 LDCM0429  CL4 HCT 116 C80(0.98)  LDD0746  [5]
 LDCM0430  CL40 HCT 116 C80(0.94)  LDD0747  [5]
 LDCM0431  CL41 HCT 116 C80(1.32)  LDD0748  [5]
 LDCM0432  CL42 HCT 116 C80(1.41)  LDD0749  [5]
 LDCM0433  CL43 HCT 116 C80(1.32)  LDD0750  [5]
 LDCM0434  CL44 HCT 116 C80(1.03)  LDD0751  [5]
 LDCM0435  CL45 HCT 116 C80(1.06)  LDD0752  [5]
 LDCM0436  CL46 HEK-293T C80(0.85)  LDD1034  [5]
 LDCM0437  CL47 HEK-293T C80(0.86)  LDD1035  [5]
 LDCM0438  CL48 HEK-293T C80(0.83)  LDD1036  [5]
 LDCM0439  CL49 HEK-293T C80(0.96)  LDD1037  [5]
 LDCM0440  CL5 HCT 116 C80(0.91)  LDD0757  [5]
 LDCM0441  CL50 HEK-293T C80(1.09)  LDD1039  [5]
 LDCM0442  CL51 HEK-293T C80(0.95)  LDD1040  [5]
 LDCM0443  CL52 HEK-293T C80(0.74)  LDD1041  [5]
 LDCM0444  CL53 HEK-293T C80(0.88)  LDD1042  [5]
 LDCM0445  CL54 HEK-293T C80(1.08)  LDD1043  [5]
 LDCM0446  CL55 HEK-293T C80(1.02)  LDD1044  [5]
 LDCM0447  CL56 HEK-293T C80(0.96)  LDD1045  [5]
 LDCM0448  CL57 HEK-293T C80(0.97)  LDD1046  [5]
 LDCM0449  CL58 HEK-293T C80(1.02)  LDD1047  [5]
 LDCM0450  CL59 HEK-293T C80(1.26)  LDD1048  [5]
 LDCM0451  CL6 HCT 116 C80(0.96)  LDD0768  [5]
 LDCM0452  CL60 HEK-293T C80(1.27)  LDD1050  [5]
 LDCM0453  CL61 HEK-293T C80(0.81)  LDD1051  [5]
 LDCM0454  CL62 HEK-293T C80(0.99)  LDD1052  [5]
 LDCM0455  CL63 HEK-293T C80(0.82)  LDD1053  [5]
 LDCM0456  CL64 HEK-293T C80(0.76)  LDD1054  [5]
 LDCM0457  CL65 HEK-293T C80(0.78)  LDD1055  [5]
 LDCM0458  CL66 HEK-293T C80(0.80)  LDD1056  [5]
 LDCM0459  CL67 HEK-293T C80(0.73)  LDD1057  [5]
 LDCM0460  CL68 HEK-293T C80(0.92)  LDD1058  [5]
 LDCM0461  CL69 HEK-293T C80(0.77)  LDD1059  [5]
 LDCM0462  CL7 HCT 116 C80(0.97)  LDD0779  [5]
 LDCM0463  CL70 HEK-293T C80(0.93)  LDD1061  [5]
 LDCM0464  CL71 HEK-293T C80(0.84)  LDD1062  [5]
 LDCM0465  CL72 HEK-293T C80(0.74)  LDD1063  [5]
 LDCM0466  CL73 HEK-293T C80(0.77)  LDD1064  [5]
 LDCM0467  CL74 HEK-293T C80(0.79)  LDD1065  [5]
 LDCM0469  CL76 HEK-293T C80(1.07)  LDD1067  [5]
 LDCM0470  CL77 HEK-293T C80(1.05)  LDD1068  [5]
 LDCM0471  CL78 HEK-293T C80(1.20)  LDD1069  [5]
 LDCM0472  CL79 HEK-293T C80(1.26)  LDD1070  [5]
 LDCM0473  CL8 HCT 116 C80(1.17)  LDD0790  [5]
 LDCM0474  CL80 HEK-293T C80(1.16)  LDD1072  [5]
 LDCM0475  CL81 HEK-293T C80(1.18)  LDD1073  [5]
 LDCM0476  CL82 HEK-293T C80(1.13)  LDD1074  [5]
 LDCM0477  CL83 HEK-293T C80(1.04)  LDD1075  [5]
 LDCM0478  CL84 HEK-293T C80(1.26)  LDD1076  [5]
 LDCM0479  CL85 HEK-293T C80(1.15)  LDD1077  [5]
 LDCM0480  CL86 HEK-293T C80(1.53)  LDD1078  [5]
 LDCM0481  CL87 HEK-293T C80(1.19)  LDD1079  [5]
 LDCM0482  CL88 HEK-293T C80(1.29)  LDD1080  [5]
 LDCM0483  CL89 HEK-293T C80(1.35)  LDD1081  [5]
 LDCM0484  CL9 HCT 116 C80(1.05)  LDD0801  [5]
 LDCM0485  CL90 HEK-293T C80(1.25)  LDD1083  [5]
 LDCM0486  CL91 HEK-293T C80(0.86)  LDD1084  [5]
 LDCM0487  CL92 HEK-293T C80(0.90)  LDD1085  [5]
 LDCM0488  CL93 HEK-293T C80(1.20)  LDD1086  [5]
 LDCM0489  CL94 HEK-293T C80(1.61)  LDD1087  [5]
 LDCM0490  CL95 HEK-293T C80(2.05)  LDD1088  [5]
 LDCM0491  CL96 HEK-293T C80(1.30)  LDD1089  [5]
 LDCM0492  CL97 HEK-293T C80(1.27)  LDD1090  [5]
 LDCM0493  CL98 HEK-293T C80(1.10)  LDD1091  [5]
 LDCM0494  CL99 HEK-293T C80(1.07)  LDD1092  [5]
 LDCM0495  E2913 HEK-293T C80(1.01)  LDD1698  [7]
 LDCM0573  Fragment11 Ramos C80(2.60)  LDD2190  [4]
 LDCM0575  Fragment13 Ramos C80(0.89)  LDD2192  [4]
 LDCM0580  Fragment21 Ramos C80(0.83)  LDD2195  [4]
 LDCM0578  Fragment27 Ramos C80(0.91)  LDD2197  [4]
 LDCM0586  Fragment28 Ramos C80(0.54)  LDD2198  [4]
 LDCM0588  Fragment30 Ramos C80(1.80)  LDD2199  [4]
 LDCM0589  Fragment31 Ramos C80(1.61)  LDD2200  [4]
 LDCM0468  Fragment33 HEK-293T C80(0.67)  LDD1066  [5]
 LDCM0596  Fragment38 Ramos C80(0.85)  LDD2203  [4]
 LDCM0427  Fragment51 HCT 116 C80(1.57)  LDD0744  [5]
 LDCM0614  Fragment56 Ramos C80(1.94)  LDD2205  [4]
 LDCM0022  KB02 HEK-293T C80(0.89)  LDD1492  [7]
 LDCM0023  KB03 HEK-293T C80(0.96)  LDD1497  [7]
 LDCM0024  KB05 HEK-293T C80(0.65)  LDD1502  [7]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C80(0.66)  LDD2097  [3]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C80(0.96)  LDD2101  [3]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C80(1.20)  LDD2105  [3]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C80(1.04)  LDD2107  [3]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C80(0.59)  LDD2115  [3]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C80(0.86)  LDD2123  [3]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C80(1.32)  LDD2127  [3]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C80(1.16)  LDD2128  [3]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C80(0.84)  LDD2129  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
ATP-dependent RNA helicase DDX3X (DDX3X) DEAD box helicase family O00571

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
2 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
3 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
4 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
5 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
6 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
7 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402