Details of the Target

General Information of Target

Target ID LDTP10873
Target Name Prefoldin subunit 5 (PFDN5)
Gene Name PFDN5
Gene ID 5204
Synonyms
MM1; PFD5; Prefoldin subunit 5; Myc modulator 1; c-Myc-binding protein Mm-1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MIPPSSPREDGVDGLPKEAVGAEQPPSPASTSSQESKLQKLKRSLSFKTKSLRSKSADNF
FQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIFKKPTF
CDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLIHEQ
FGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEEA
NGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTYVALYKFVPQE
NEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKE
QGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI
Target Bioclass
Other
Family
Prefoldin subunit alpha family
Subcellular location
Cytoplasm; Nucleus
Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.
Uniprot ID
Q99471
Ensemble ID
ENST00000243040.10
HGNC ID
HGNC:8869

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A375 SNV: p.P65S DBIA    Probe Info 
MOLT4 SNV: p.E80K IA-alkyne    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 24 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
TH211
 Probe Info  		Y43(15.51)  LDD0260  [2]
C-Sul
 Probe Info  		3.26  LDD0066  [3]
TH214
 Probe Info  		Y43(20.00)  LDD0258  [2]
TH216
 Probe Info  		Y71(16.73)  LDD0259  [2]
STPyne
 Probe Info  		K106(6.18); K128(7.54); K42(8.13)  LDD0277  [4]
BTD
 Probe Info  		C49(3.44)  LDD1699  [5]
ONAyne
 Probe Info  		K106(10.00)  LDD0275  [4]
DBIA
 Probe Info  		C49(1.14)  LDD0080  [6]
5E-2FA
 Probe Info  		N.A.  LDD2235  [7]
ATP probe
 Probe Info  		K47(0.00); K42(0.00); K106(0.00)  LDD0199  [8]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [9]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [9]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [9]
ATP probe
 Probe Info  		N.A.  LDD0035  [10]
IPM
 Probe Info  		N.A.  LDD0025  [11]
TFBX
 Probe Info  		N.A.  LDD0027  [11]
PF-06672131
 Probe Info  		N.A.  LDD0152  [12]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [13]
1c-yne
 Probe Info  		N.A.  LDD0228  [14]
Acrolein
 Probe Info  		N.A.  LDD0217  [15]
Methacrolein
 Probe Info  		N.A.  LDD0218  [15]
AOyne
 Probe Info  		15.00  LDD0443  [16]
NAIA_5
 Probe Info  		N.A.  LDD2223  [17]
PAL-AfBPP Probe
Click To Hide/Show 8 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C278
 Probe Info  		50.21  LDD1948  [18]
C284
 Probe Info  		22.63  LDD1954  [18]
FFF probe11
 Probe Info  		11.71  LDD0472  [19]
FFF probe13
 Probe Info  		8.88  LDD0476  [19]
FFF probe14
 Probe Info  		20.00  LDD0477  [19]
FFF probe2
 Probe Info  		14.18  LDD0463  [19]
FFF probe3
 Probe Info  		8.53  LDD0465  [19]
Probe 12
 Probe Info  		N.A.  LDD0420  [20]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C49(0.35)  LDD2142  [5]
 LDCM0214  AC1 HCT 116 C49(1.02)  LDD0531  [6]
 LDCM0215  AC10 HCT 116 C49(1.02)  LDD0532  [6]
 LDCM0216  AC100 HCT 116 C49(0.89)  LDD0533  [6]
 LDCM0217  AC101 HCT 116 C49(0.85)  LDD0534  [6]
 LDCM0218  AC102 HCT 116 C49(0.88)  LDD0535  [6]
 LDCM0219  AC103 HCT 116 C49(0.88)  LDD0536  [6]
 LDCM0220  AC104 HCT 116 C49(0.86)  LDD0537  [6]
 LDCM0221  AC105 HCT 116 C49(0.86)  LDD0538  [6]
 LDCM0222  AC106 HCT 116 C49(0.90)  LDD0539  [6]
 LDCM0223  AC107 HCT 116 C49(0.85)  LDD0540  [6]
 LDCM0224  AC108 HCT 116 C49(1.36)  LDD0541  [6]
 LDCM0225  AC109 HCT 116 C49(1.19)  LDD0542  [6]
 LDCM0226  AC11 HCT 116 C49(1.00)  LDD0543  [6]
 LDCM0227  AC110 HCT 116 C49(1.15)  LDD0544  [6]
 LDCM0228  AC111 HCT 116 C49(1.18)  LDD0545  [6]
 LDCM0229  AC112 HCT 116 C49(0.83)  LDD0546  [6]
 LDCM0230  AC113 HCT 116 C49(1.12)  LDD0547  [6]
 LDCM0231  AC114 HCT 116 C49(1.07)  LDD0548  [6]
 LDCM0232  AC115 HCT 116 C49(1.03)  LDD0549  [6]
 LDCM0233  AC116 HCT 116 C49(1.13)  LDD0550  [6]
 LDCM0234  AC117 HCT 116 C49(1.07)  LDD0551  [6]
 LDCM0235  AC118 HCT 116 C49(1.01)  LDD0552  [6]
 LDCM0236  AC119 HCT 116 C49(1.07)  LDD0553  [6]
 LDCM0237  AC12 HCT 116 C49(1.12)  LDD0554  [6]
 LDCM0238  AC120 HCT 116 C49(0.94)  LDD0555  [6]
 LDCM0239  AC121 HCT 116 C49(0.98)  LDD0556  [6]
 LDCM0240  AC122 HCT 116 C49(0.96)  LDD0557  [6]
 LDCM0241  AC123 HCT 116 C49(0.96)  LDD0558  [6]
 LDCM0242  AC124 HCT 116 C49(0.97)  LDD0559  [6]
 LDCM0243  AC125 HCT 116 C49(1.03)  LDD0560  [6]
 LDCM0244  AC126 HCT 116 C49(1.04)  LDD0561  [6]
 LDCM0245  AC127 HCT 116 C49(1.04)  LDD0562  [6]
 LDCM0246  AC128 HCT 116 C49(1.27)  LDD0563  [6]
 LDCM0247  AC129 HCT 116 C49(1.00)  LDD0564  [6]
 LDCM0249  AC130 HCT 116 C49(1.11)  LDD0566  [6]
 LDCM0250  AC131 HCT 116 C49(1.01)  LDD0567  [6]
 LDCM0251  AC132 HCT 116 C49(1.19)  LDD0568  [6]
 LDCM0252  AC133 HCT 116 C49(1.24)  LDD0569  [6]
 LDCM0253  AC134 HCT 116 C49(1.06)  LDD0570  [6]
 LDCM0254  AC135 HCT 116 C49(1.22)  LDD0571  [6]
 LDCM0255  AC136 HCT 116 C49(1.14)  LDD0572  [6]
 LDCM0256  AC137 HCT 116 C49(1.06)  LDD0573  [6]
 LDCM0257  AC138 HCT 116 C49(1.22)  LDD0574  [6]
 LDCM0258  AC139 HCT 116 C49(1.12)  LDD0575  [6]
 LDCM0259  AC14 HCT 116 C49(0.96)  LDD0576  [6]
 LDCM0260  AC140 HCT 116 C49(1.20)  LDD0577  [6]
 LDCM0261  AC141 HCT 116 C49(1.15)  LDD0578  [6]
 LDCM0262  AC142 HCT 116 C49(1.19)  LDD0579  [6]
 LDCM0263  AC143 HCT 116 C49(0.99)  LDD0580  [6]
 LDCM0264  AC144 HCT 116 C49(0.83)  LDD0581  [6]
 LDCM0265  AC145 HCT 116 C49(0.86)  LDD0582  [6]
 LDCM0266  AC146 HCT 116 C49(0.85)  LDD0583  [6]
 LDCM0267  AC147 HCT 116 C49(0.95)  LDD0584  [6]
 LDCM0268  AC148 HCT 116 C49(1.00)  LDD0585  [6]
 LDCM0269  AC149 HCT 116 C49(0.82)  LDD0586  [6]
 LDCM0270  AC15 HCT 116 C49(0.95)  LDD0587  [6]
 LDCM0271  AC150 HCT 116 C49(0.91)  LDD0588  [6]
 LDCM0272  AC151 HCT 116 C49(0.97)  LDD0589  [6]
 LDCM0273  AC152 HCT 116 C49(0.80)  LDD0590  [6]
 LDCM0274  AC153 HCT 116 C49(1.00)  LDD0591  [6]
 LDCM0621  AC154 HCT 116 C49(0.84)  LDD2158  [6]
 LDCM0622  AC155 HCT 116 C49(0.94)  LDD2159  [6]
 LDCM0623  AC156 HCT 116 C49(0.95)  LDD2160  [6]
 LDCM0624  AC157 HCT 116 C49(0.83)  LDD2161  [6]
 LDCM0276  AC17 HCT 116 C49(0.97)  LDD0593  [6]
 LDCM0277  AC18 HCT 116 C49(0.94)  LDD0594  [6]
 LDCM0278  AC19 HCT 116 C49(0.92)  LDD0595  [6]
 LDCM0279  AC2 HCT 116 C49(0.91)  LDD0596  [6]
 LDCM0280  AC20 HCT 116 C49(0.94)  LDD0597  [6]
 LDCM0281  AC21 HCT 116 C49(0.95)  LDD0598  [6]
 LDCM0282  AC22 HCT 116 C49(1.07)  LDD0599  [6]
 LDCM0283  AC23 HCT 116 C49(1.03)  LDD0600  [6]
 LDCM0284  AC24 HCT 116 C49(0.93)  LDD0601  [6]
 LDCM0285  AC25 HCT 116 C49(0.91)  LDD0602  [6]
 LDCM0286  AC26 HCT 116 C49(0.95)  LDD0603  [6]
 LDCM0287  AC27 HCT 116 C49(0.89)  LDD0604  [6]
 LDCM0288  AC28 HCT 116 C49(0.88)  LDD0605  [6]
 LDCM0289  AC29 HCT 116 C49(0.87)  LDD0606  [6]
 LDCM0290  AC3 HCT 116 C49(0.93)  LDD0607  [6]
 LDCM0291  AC30 HCT 116 C49(0.94)  LDD0608  [6]
 LDCM0292  AC31 HCT 116 C49(0.87)  LDD0609  [6]
 LDCM0293  AC32 HCT 116 C49(0.87)  LDD0610  [6]
 LDCM0294  AC33 HCT 116 C49(0.81)  LDD0611  [6]
 LDCM0295  AC34 HCT 116 C49(0.92)  LDD0612  [6]
 LDCM0296  AC35 HCT 116 C49(1.08)  LDD0613  [6]
 LDCM0297  AC36 HCT 116 C49(1.12)  LDD0614  [6]
 LDCM0298  AC37 HCT 116 C49(1.05)  LDD0615  [6]
 LDCM0299  AC38 HCT 116 C49(0.98)  LDD0616  [6]
 LDCM0300  AC39 HCT 116 C49(1.11)  LDD0617  [6]
 LDCM0301  AC4 HCT 116 C49(0.99)  LDD0618  [6]
 LDCM0302  AC40 HCT 116 C49(1.06)  LDD0619  [6]
 LDCM0303  AC41 HCT 116 C49(1.05)  LDD0620  [6]
 LDCM0304  AC42 HCT 116 C49(1.01)  LDD0621  [6]
 LDCM0305  AC43 HCT 116 C49(1.00)  LDD0622  [6]
 LDCM0306  AC44 HCT 116 C49(1.01)  LDD0623  [6]
 LDCM0307  AC45 HCT 116 C49(1.06)  LDD0624  [6]
 LDCM0308  AC46 HCT 116 C49(1.13)  LDD0625  [6]
 LDCM0309  AC47 HCT 116 C49(1.16)  LDD0626  [6]
 LDCM0310  AC48 HCT 116 C49(1.13)  LDD0627  [6]
 LDCM0311  AC49 HCT 116 C49(1.13)  LDD0628  [6]
 LDCM0312  AC5 HCT 116 C49(1.04)  LDD0629  [6]
 LDCM0313  AC50 HCT 116 C49(1.00)  LDD0630  [6]
 LDCM0314  AC51 HCT 116 C49(1.06)  LDD0631  [6]
 LDCM0315  AC52 HCT 116 C49(1.12)  LDD0632  [6]
 LDCM0316  AC53 HCT 116 C49(0.97)  LDD0633  [6]
 LDCM0317  AC54 HCT 116 C49(1.16)  LDD0634  [6]
 LDCM0318  AC55 HCT 116 C49(1.09)  LDD0635  [6]
 LDCM0319  AC56 HCT 116 C49(1.12)  LDD0636  [6]
 LDCM0320  AC57 HCT 116 C49(1.03)  LDD0637  [6]
 LDCM0321  AC58 HCT 116 C49(1.01)  LDD0638  [6]
 LDCM0322  AC59 HCT 116 C49(1.08)  LDD0639  [6]
 LDCM0323  AC6 HCT 116 C49(0.93)  LDD0640  [6]
 LDCM0324  AC60 HCT 116 C49(1.00)  LDD0641  [6]
 LDCM0325  AC61 HCT 116 C49(1.34)  LDD0642  [6]
 LDCM0326  AC62 HCT 116 C49(1.23)  LDD0643  [6]
 LDCM0327  AC63 HCT 116 C49(0.99)  LDD0644  [6]
 LDCM0328  AC64 HCT 116 C49(1.17)  LDD0645  [6]
 LDCM0329  AC65 HCT 116 C49(1.41)  LDD0646  [6]
 LDCM0330  AC66 HCT 116 C49(1.25)  LDD0647  [6]
 LDCM0331  AC67 HCT 116 C49(1.32)  LDD0648  [6]
 LDCM0332  AC68 HCT 116 C49(1.05)  LDD0649  [6]
 LDCM0333  AC69 HCT 116 C49(0.98)  LDD0650  [6]
 LDCM0334  AC7 HCT 116 C49(1.06)  LDD0651  [6]
 LDCM0335  AC70 HCT 116 C49(0.99)  LDD0652  [6]
 LDCM0336  AC71 HCT 116 C49(1.00)  LDD0653  [6]
 LDCM0337  AC72 HCT 116 C49(1.08)  LDD0654  [6]
 LDCM0338  AC73 HCT 116 C49(1.06)  LDD0655  [6]
 LDCM0339  AC74 HCT 116 C49(1.10)  LDD0656  [6]
 LDCM0340  AC75 HCT 116 C49(1.05)  LDD0657  [6]
 LDCM0341  AC76 HCT 116 C49(1.05)  LDD0658  [6]
 LDCM0342  AC77 HCT 116 C49(0.97)  LDD0659  [6]
 LDCM0343  AC78 HCT 116 C49(0.93)  LDD0660  [6]
 LDCM0344  AC79 HCT 116 C49(1.03)  LDD0661  [6]
 LDCM0345  AC8 HCT 116 C49(1.04)  LDD0662  [6]
 LDCM0346  AC80 HCT 116 C49(1.01)  LDD0663  [6]
 LDCM0347  AC81 HCT 116 C49(1.00)  LDD0664  [6]
 LDCM0348  AC82 HCT 116 C49(1.21)  LDD0665  [6]
 LDCM0349  AC83 HCT 116 C49(1.00)  LDD0666  [6]
 LDCM0350  AC84 HCT 116 C49(1.08)  LDD0667  [6]
 LDCM0351  AC85 HCT 116 C49(1.05)  LDD0668  [6]
 LDCM0352  AC86 HCT 116 C49(0.96)  LDD0669  [6]
 LDCM0353  AC87 HCT 116 C49(1.03)  LDD0670  [6]
 LDCM0354  AC88 HCT 116 C49(1.05)  LDD0671  [6]
 LDCM0355  AC89 HCT 116 C49(0.94)  LDD0672  [6]
 LDCM0357  AC90 HCT 116 C49(1.08)  LDD0674  [6]
 LDCM0358  AC91 HCT 116 C49(1.07)  LDD0675  [6]
 LDCM0359  AC92 HCT 116 C49(1.02)  LDD0676  [6]
 LDCM0360  AC93 HCT 116 C49(1.06)  LDD0677  [6]
 LDCM0361  AC94 HCT 116 C49(0.96)  LDD0678  [6]
 LDCM0362  AC95 HCT 116 C49(0.90)  LDD0679  [6]
 LDCM0363  AC96 HCT 116 C49(0.96)  LDD0680  [6]
 LDCM0364  AC97 HCT 116 C49(1.02)  LDD0681  [6]
 LDCM0365  AC98 HCT 116 C49(0.85)  LDD0682  [6]
 LDCM0366  AC99 HCT 116 C49(0.90)  LDD0683  [6]
 LDCM0520  AKOS000195272 MDA-MB-231 C49(0.64)  LDD2113  [5]
 LDCM0248  AKOS034007472 HCT 116 C49(1.03)  LDD0565  [6]
 LDCM0356  AKOS034007680 HCT 116 C49(1.00)  LDD0673  [6]
 LDCM0275  AKOS034007705 HCT 116 C49(1.03)  LDD0592  [6]
 LDCM0020  ARS-1620 HCC44 C49(1.08)  LDD2171  [6]
 LDCM0632  CL-Sc Hep-G2 C49(1.04)  LDD2227  [17]
 LDCM0367  CL1 HCT 116 C49(1.04)  LDD0684  [6]
 LDCM0368  CL10 HCT 116 C49(1.00)  LDD0685  [6]
 LDCM0369  CL100 HCT 116 C49(0.99)  LDD0686  [6]
 LDCM0370  CL101 HCT 116 C49(0.94)  LDD0687  [6]
 LDCM0371  CL102 HCT 116 C49(1.01)  LDD0688  [6]
 LDCM0372  CL103 HCT 116 C49(1.00)  LDD0689  [6]
 LDCM0373  CL104 HCT 116 C49(0.99)  LDD0690  [6]
 LDCM0374  CL105 HCT 116 C49(0.96)  LDD0691  [6]
 LDCM0375  CL106 HCT 116 C49(0.96)  LDD0692  [6]
 LDCM0376  CL107 HCT 116 C49(1.02)  LDD0693  [6]
 LDCM0377  CL108 HCT 116 C49(0.96)  LDD0694  [6]
 LDCM0378  CL109 HCT 116 C49(0.91)  LDD0695  [6]
 LDCM0379  CL11 HCT 116 C49(1.02)  LDD0696  [6]
 LDCM0380  CL110 HCT 116 C49(0.93)  LDD0697  [6]
 LDCM0381  CL111 HCT 116 C49(0.96)  LDD0698  [6]
 LDCM0382  CL112 HCT 116 C49(0.96)  LDD0699  [6]
 LDCM0383  CL113 HCT 116 C49(0.91)  LDD0700  [6]
 LDCM0384  CL114 HCT 116 C49(1.03)  LDD0701  [6]
 LDCM0385  CL115 HCT 116 C49(0.91)  LDD0702  [6]
 LDCM0386  CL116 HCT 116 C49(0.93)  LDD0703  [6]
 LDCM0387  CL117 HCT 116 C49(1.21)  LDD0704  [6]
 LDCM0388  CL118 HCT 116 C49(1.01)  LDD0705  [6]
 LDCM0389  CL119 HCT 116 C49(1.02)  LDD0706  [6]
 LDCM0390  CL12 HCT 116 C49(1.04)  LDD0707  [6]
 LDCM0391  CL120 HCT 116 C49(1.10)  LDD0708  [6]
 LDCM0392  CL121 HCT 116 C49(1.13)  LDD0709  [6]
 LDCM0393  CL122 HCT 116 C49(1.04)  LDD0710  [6]
 LDCM0394  CL123 HCT 116 C49(1.00)  LDD0711  [6]
 LDCM0395  CL124 HCT 116 C49(1.11)  LDD0712  [6]
 LDCM0396  CL125 HCT 116 C49(1.06)  LDD0713  [6]
 LDCM0397  CL126 HCT 116 C49(1.28)  LDD0714  [6]
 LDCM0398  CL127 HCT 116 C49(1.12)  LDD0715  [6]
 LDCM0399  CL128 HCT 116 C49(1.11)  LDD0716  [6]
 LDCM0400  CL13 HCT 116 C49(0.95)  LDD0717  [6]
 LDCM0401  CL14 HCT 116 C49(0.90)  LDD0718  [6]
 LDCM0402  CL15 HCT 116 C49(0.89)  LDD0719  [6]
 LDCM0403  CL16 HCT 116 C49(1.02)  LDD0720  [6]
 LDCM0404  CL17 HCT 116 C49(1.06)  LDD0721  [6]
 LDCM0405  CL18 HCT 116 C49(0.85)  LDD0722  [6]
 LDCM0406  CL19 HCT 116 C49(0.93)  LDD0723  [6]
 LDCM0407  CL2 HCT 116 C49(0.96)  LDD0724  [6]
 LDCM0408  CL20 HCT 116 C49(0.89)  LDD0725  [6]
 LDCM0409  CL21 HCT 116 C49(0.91)  LDD0726  [6]
 LDCM0410  CL22 HCT 116 C49(1.01)  LDD0727  [6]
 LDCM0411  CL23 HCT 116 C49(1.02)  LDD0728  [6]
 LDCM0412  CL24 HCT 116 C49(1.02)  LDD0729  [6]
 LDCM0413  CL25 HCT 116 C49(0.99)  LDD0730  [6]
 LDCM0414  CL26 HCT 116 C49(0.99)  LDD0731  [6]
 LDCM0415  CL27 HCT 116 C49(0.95)  LDD0732  [6]
 LDCM0416  CL28 HCT 116 C49(0.91)  LDD0733  [6]
 LDCM0417  CL29 HCT 116 C49(0.92)  LDD0734  [6]
 LDCM0418  CL3 HCT 116 C49(1.03)  LDD0735  [6]
 LDCM0419  CL30 HCT 116 C49(0.94)  LDD0736  [6]
 LDCM0420  CL31 HCT 116 C49(0.93)  LDD0737  [6]
 LDCM0421  CL32 HCT 116 C49(0.89)  LDD0738  [6]
 LDCM0422  CL33 HCT 116 C49(0.83)  LDD0739  [6]
 LDCM0423  CL34 HCT 116 C49(0.90)  LDD0740  [6]
 LDCM0424  CL35 HCT 116 C49(0.86)  LDD0741  [6]
 LDCM0425  CL36 HCT 116 C49(0.91)  LDD0742  [6]
 LDCM0426  CL37 HCT 116 C49(1.01)  LDD0743  [6]
 LDCM0428  CL39 HCT 116 C49(0.97)  LDD0745  [6]
 LDCM0429  CL4 HCT 116 C49(0.88)  LDD0746  [6]
 LDCM0430  CL40 HCT 116 C49(0.94)  LDD0747  [6]
 LDCM0431  CL41 HCT 116 C49(0.81)  LDD0748  [6]
 LDCM0432  CL42 HCT 116 C49(1.18)  LDD0749  [6]
 LDCM0433  CL43 HCT 116 C49(0.90)  LDD0750  [6]
 LDCM0434  CL44 HCT 116 C49(0.92)  LDD0751  [6]
 LDCM0435  CL45 HCT 116 C49(0.90)  LDD0752  [6]
 LDCM0436  CL46 HCT 116 C49(1.04)  LDD0753  [6]
 LDCM0437  CL47 HCT 116 C49(1.04)  LDD0754  [6]
 LDCM0438  CL48 HCT 116 C49(0.99)  LDD0755  [6]
 LDCM0439  CL49 HCT 116 C49(0.91)  LDD0756  [6]
 LDCM0440  CL5 HCT 116 C49(0.97)  LDD0757  [6]
 LDCM0441  CL50 HCT 116 C49(0.98)  LDD0758  [6]
 LDCM0442  CL51 HCT 116 C49(1.02)  LDD0759  [6]
 LDCM0443  CL52 HCT 116 C49(1.10)  LDD0760  [6]
 LDCM0444  CL53 HCT 116 C49(0.99)  LDD0761  [6]
 LDCM0445  CL54 HCT 116 C49(1.01)  LDD0762  [6]
 LDCM0446  CL55 HCT 116 C49(0.97)  LDD0763  [6]
 LDCM0447  CL56 HCT 116 C49(1.17)  LDD0764  [6]
 LDCM0448  CL57 HCT 116 C49(1.01)  LDD0765  [6]
 LDCM0449  CL58 HCT 116 C49(0.93)  LDD0766  [6]
 LDCM0450  CL59 HCT 116 C49(1.02)  LDD0767  [6]
 LDCM0451  CL6 HCT 116 C49(0.91)  LDD0768  [6]
 LDCM0452  CL60 HCT 116 C49(0.93)  LDD0769  [6]
 LDCM0453  CL61 HCT 116 C49(1.01)  LDD0770  [6]
 LDCM0454  CL62 HCT 116 C49(0.89)  LDD0771  [6]
 LDCM0455  CL63 HCT 116 C49(1.02)  LDD0772  [6]
 LDCM0456  CL64 HCT 116 C49(0.93)  LDD0773  [6]
 LDCM0457  CL65 HCT 116 C49(0.97)  LDD0774  [6]
 LDCM0458  CL66 HCT 116 C49(1.11)  LDD0775  [6]
 LDCM0459  CL67 HCT 116 C49(1.00)  LDD0776  [6]
 LDCM0460  CL68 HCT 116 C49(1.04)  LDD0777  [6]
 LDCM0461  CL69 HCT 116 C49(0.85)  LDD0778  [6]
 LDCM0462  CL7 HCT 116 C49(0.98)  LDD0779  [6]
 LDCM0463  CL70 HCT 116 C49(0.97)  LDD0780  [6]
 LDCM0464  CL71 HCT 116 C49(1.08)  LDD0781  [6]
 LDCM0465  CL72 HCT 116 C49(0.90)  LDD0782  [6]
 LDCM0466  CL73 HCT 116 C49(0.97)  LDD0783  [6]
 LDCM0467  CL74 HCT 116 C49(0.93)  LDD0784  [6]
 LDCM0469  CL76 HCT 116 C49(1.12)  LDD0786  [6]
 LDCM0470  CL77 HCT 116 C49(1.13)  LDD0787  [6]
 LDCM0471  CL78 HCT 116 C49(1.10)  LDD0788  [6]
 LDCM0472  CL79 HCT 116 C49(1.06)  LDD0789  [6]
 LDCM0473  CL8 HCT 116 C49(0.90)  LDD0790  [6]
 LDCM0474  CL80 HCT 116 C49(0.96)  LDD0791  [6]
 LDCM0475  CL81 HCT 116 C49(1.04)  LDD0792  [6]
 LDCM0476  CL82 HCT 116 C49(1.16)  LDD0793  [6]
 LDCM0477  CL83 HCT 116 C49(1.22)  LDD0794  [6]
 LDCM0478  CL84 HCT 116 C49(1.26)  LDD0795  [6]
 LDCM0479  CL85 HCT 116 C49(1.16)  LDD0796  [6]
 LDCM0480  CL86 HCT 116 C49(1.13)  LDD0797  [6]
 LDCM0481  CL87 HCT 116 C49(1.10)  LDD0798  [6]
 LDCM0482  CL88 HCT 116 C49(1.15)  LDD0799  [6]
 LDCM0483  CL89 HCT 116 C49(1.34)  LDD0800  [6]
 LDCM0484  CL9 HCT 116 C49(0.97)  LDD0801  [6]
 LDCM0485  CL90 HCT 116 C49(1.12)  LDD0802  [6]
 LDCM0486  CL91 HCT 116 C49(0.95)  LDD0803  [6]
 LDCM0487  CL92 HCT 116 C49(0.99)  LDD0804  [6]
 LDCM0488  CL93 HCT 116 C49(1.05)  LDD0805  [6]
 LDCM0489  CL94 HCT 116 C49(0.78)  LDD0806  [6]
 LDCM0490  CL95 HCT 116 C49(0.93)  LDD0807  [6]
 LDCM0491  CL96 HCT 116 C49(0.98)  LDD0808  [6]
 LDCM0492  CL97 HCT 116 C49(0.93)  LDD0809  [6]
 LDCM0493  CL98 HCT 116 C49(0.95)  LDD0810  [6]
 LDCM0494  CL99 HCT 116 C49(1.06)  LDD0811  [6]
 LDCM0165  Compound 9 HL-60 N.A.  LDD0420  [20]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C49(0.90)  LDD1702  [5]
 LDCM0625  F8 Ramos C49(0.83)  LDD2187  [21]
 LDCM0572  Fragment10 Ramos C49(0.91)  LDD2189  [21]
 LDCM0573  Fragment11 Ramos C49(0.05)  LDD2190  [21]
 LDCM0574  Fragment12 Ramos C49(0.94)  LDD2191  [21]
 LDCM0575  Fragment13 Ramos C49(1.27)  LDD2192  [21]
 LDCM0576  Fragment14 Ramos C49(0.67)  LDD2193  [21]
 LDCM0579  Fragment20 Ramos C49(0.70)  LDD2194  [21]
 LDCM0580  Fragment21 Ramos C49(1.28)  LDD2195  [21]
 LDCM0582  Fragment23 Ramos C49(2.20)  LDD2196  [21]
 LDCM0578  Fragment27 Ramos C49(1.29)  LDD2197  [21]
 LDCM0586  Fragment28 Ramos C49(0.87)  LDD2198  [21]
 LDCM0588  Fragment30 Ramos C49(1.46)  LDD2199  [21]
 LDCM0589  Fragment31 Ramos C49(1.12)  LDD2200  [21]
 LDCM0590  Fragment32 Ramos C49(0.92)  LDD2201  [21]
 LDCM0468  Fragment33 HCT 116 C49(0.96)  LDD0785  [6]
 LDCM0596  Fragment38 Ramos C49(1.13)  LDD2203  [21]
 LDCM0566  Fragment4 Ramos C49(0.70)  LDD2184  [21]
 LDCM0427  Fragment51 HCT 116 C49(0.92)  LDD0744  [6]
 LDCM0610  Fragment52 Ramos C49(1.31)  LDD2204  [21]
 LDCM0614  Fragment56 Ramos C49(1.61)  LDD2205  [21]
 LDCM0569  Fragment7 Ramos C49(0.66)  LDD2186  [21]
 LDCM0571  Fragment9 Ramos C49(0.83)  LDD2188  [21]
 LDCM0022  KB02 HCT 116 C49(1.14)  LDD0080  [6]
 LDCM0023  KB03 HCT 116 C49(1.35)  LDD0081  [6]
 LDCM0024  KB05 HCT 116 C49(1.36)  LDD0082  [6]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C49(0.83)  LDD2102  [5]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C49(1.00)  LDD2092  [5]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C49(1.93)  LDD2094  [5]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C49(0.52)  LDD2096  [5]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C49(0.60)  LDD2097  [5]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C49(0.90)  LDD2098  [5]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C49(1.76)  LDD2099  [5]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C49(0.43)  LDD2100  [5]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C49(0.36)  LDD2101  [5]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C49(0.37)  LDD2104  [5]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C49(1.16)  LDD2105  [5]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C49(1.00)  LDD2107  [5]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C49(0.52)  LDD2108  [5]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C49(0.63)  LDD2109  [5]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C49(0.45)  LDD2110  [5]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C49(1.30)  LDD2111  [5]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C49(0.36)  LDD2114  [5]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C49(0.33)  LDD2115  [5]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C49(1.06)  LDD2116  [5]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C49(0.95)  LDD2120  [5]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C49(1.02)  LDD2122  [5]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C49(1.02)  LDD2124  [5]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C49(0.97)  LDD2127  [5]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C49(0.57)  LDD2133  [5]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C49(0.59)  LDD2134  [5]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C49(1.69)  LDD2135  [5]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C49(1.47)  LDD1700  [5]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C49(1.29)  LDD2140  [5]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C49(0.57)  LDD2141  [5]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C49(0.28)  LDD2145  [5]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C49(0.41)  LDD2148  [5]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C49(1.06)  LDD2149  [5]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C49(0.89)  LDD2151  [5]
 LDCM0131  RA190 MM1.R C49(1.27)  LDD0304  [22]
 LDCM0021  THZ1 HCT 116 C49(1.08)  LDD2173  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 12 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) 5'-AMP-activated protein kinase beta subunit family O43741
Maspardin (SPG21) AB hydrolase superfamily Q9NZD8
Lysine-specific histone demethylase 1A (KDM1A) Flavin monoamine oxidase family O60341
Glycerate kinase (GLYCTK) Glycerate kinase type-2 family Q8IVS8
Glutathione S-transferase omega-2 (GSTO2) Omega family Q9H4Y5
Protein N-lysine methyltransferase METTL21A (METTL21A) METTL21 family Q8WXB1
Protein N-terminal glutamine amidohydrolase (NTAQ1) NTAQ1 family Q96HA8
Proteasome subunit beta type-4 (PSMB4) Peptidase T1B family P28070
Dual specificity mitogen-activated protein kinase kinase 5 (MAP2K5) STE Ser/Thr protein kinase family Q13163
Protein yippee-like 5 (YPEL5) Yippee family P62699
E3 ubiquitin-protein ligase LNX (LNX1) . Q8TBB1
Glutaredoxin-3 (GLRX3) . O76003
Transporter and channel
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Huntingtin (HTT) Huntingtin family P42858
Peroxisome assembly protein 26 (PEX26) Peroxin-26 family Q7Z412
Protein shisa-6 (SHISA6) Shisa family Q6ZSJ9
Sodium channel modifier 1 (SCNM1) . Q9BWG6
Syntenin-1 (SDCBP) . O00560
Transcription factor
Click To Hide/Show 22 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein Hox-B9 (HOXB9) Abd-B homeobox family P17482
Homeobox protein Hox-C8 (HOXC8) Antp homeobox family P31273
Doublesex- and mab-3-related transcription factor 3 (DMRT3) DMRT family Q9NQL9
Ventral anterior homeobox 2 (VAX2) EMX homeobox family Q9UIW0
ETS domain-containing protein Elk-3 (ELK3) ETS family P41970
Zinc finger protein Aiolos (IKZF3) Ikaros C2H2-type zinc-finger protein family Q9UKT9
Vascular endothelial zinc finger 1 (VEZF1) Krueppel C2H2-type zinc-finger protein family Q14119
Pituitary homeobox 1 (PITX1) Paired homeobox family P78337
PHD finger protein 1 (PHF1) Polycomblike family O43189
Zinc finger protein SNAI1 (SNAI1) Snail C2H2-type zinc-finger protein family O95863
Krueppel-like factor 11 (KLF11) Sp1 C2H2-type zinc-finger protein family O14901
Iroquois-class homeodomain protein IRX-2 (IRX2) TALE/IRO homeobox family Q9BZI1
Iroquois-class homeodomain protein IRX-6 (IRX6) TALE/IRO homeobox family P78412
B-cell lymphoma 6 protein (BCL6) . P41182
Class E basic helix-loop-helix protein 40 (BHLHE40) . O14503
Hematopoietically-expressed homeobox protein HHEX (HHEX) . Q03014
Neurogenin-2 (NEUROG2) . Q9H2A3
Paired box protein Pax-9 (PAX9) . P55771
Pogo transposable element with ZNF domain (POGZ) . Q7Z3K3
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 (SOHLH1) . Q5JUK2
T-box transcription factor TBX3 (TBX3) . O15119
Transcription factor 19 (TCF19) . Q9Y242
Immunoglobulin
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hyaluronan and proteoglycan link protein 2 (HAPLN2) HAPLN family Q9GZV7
Myotilin (MYOT) Myotilin/palladin family Q9UBF9
Other
Click To Hide/Show 42 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Atos homolog protein B (ATOSB) ATOS family Q7L5A3
Calcium-binding and coiled-coil domain-containing protein 2 (CALCOCO2) CALCOCO family Q13137
Docking protein 4 (DOK4) DOK family, Type B subfamily Q8TEW6
Protein FAM110A (FAM110A) FAM110 family Q9BQ89
Stabilizer of axonemal microtubules 1 (SAXO1) FAM154 family Q8IYX7
Protein FAM221A (FAM221A) FAM221 family A4D161
Protein FAM222B (FAM222B) FAM222 family Q8WU58
Protein FAM90A1 (FAM90A1) FAM90 family Q86YD7
Protein INCA1 (INCA1) INCA family Q0VD86
Mitotic interactor and substrate of PLK1 (MISP) MISP family Q8IVT2
Large ribosomal subunit protein mL45 (MRPL45) Mitochondrion-specific ribosomal protein mL45 family Q9BRJ2
Myozenin-1 (MYOZ1) Myozenin family Q9NP98
Proteasome activator complex subunit 3 (PSME3) PA28 family P61289
Prefoldin subunit 3 (VBP1) Prefoldin subunit alpha family P61758
Prefoldin subunit 2 (PFDN2) Prefoldin subunit beta family Q9UHV9
Pre-mRNA-splicing factor 18 (PRPF18) PRP18 family Q99633
RIB43A-like with coiled-coils protein 1 (RIBC1) RIB43A family Q8N443
Protein ripply1 (RIPPLY1) Ripply family Q0D2K3
Arginine/serine-rich coiled-coil protein 2 (RSRC2) RSRC2 family Q7L4I2
SLAIN motif-containing protein 1 (SLAIN1) SLAIN motif-containing family Q8ND83
Nonsense-mediated mRNA decay factor SMG9 (SMG9) SMG9 family Q9H0W8
Pre-mRNA-splicing factor SPF27 (BCAS2) SPF27 family O75934
Synaptotagmin-17 (SYT17) Synaptotagmin family Q9BSW7
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) TAF6 family Q9Y6J9
Synaptic plasticity regulator PANTS (C22orf39) UPF0545 family Q6P5X5
Transcription cofactor vestigial-like protein 1 (VGLL1) Vestigial family Q99990
Ankyrin repeat domain-containing protein 55 (ANKRD55) . Q3KP44
AP-4 complex accessory subunit RUSC1 (RUSC1) . Q9BVN2
BTB/POZ domain-containing protein KCTD9 (KCTD9) . Q7L273
Ciliary microtubule inner protein 1 (CIMIP1) . Q9H1P6
Espin-like protein (ESPNL) . Q6ZVH7
G patch domain and ankyrin repeat-containing protein 1 (GPANK1) . O95872
Kelch-like protein 38 (KLHL38) . Q2WGJ6
Kelch-like protein 42 (KLHL42) . Q9P2K6
PHD finger protein 24 (PHF24) . Q9UPV7
Proline-rich protein 35 (PRR35) . P0CG20
Protein SPMIP2 (SPMIP2) . Q96LM5
Protein TFG (TFG) . Q92734
Sperm-associated microtubule inner protein 4 (SPMIP4) . Q8N865
U11/U12 small nuclear ribonucleoprotein 25 kDa protein (SNRNP25) . Q9BV90
Uncharacterized protein C10orf55 (C10orf55) . Q5SWW7
Uncharacterized protein C10orf62 (C10orf62) . Q5T681

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
3 Low-Toxicity Sulfonium-Based Probes for Cysteine-Specific Profiling in Live Cells. Anal Chem. 2022 Mar 15;94(10):4366-4372. doi: 10.1021/acs.analchem.1c05129. Epub 2022 Mar 4.
4 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
5 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
8 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
9 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
10 Comparison of Quantitative Mass Spectrometry Platforms for Monitoring Kinase ATP Probe Uptake in Lung Cancer. J Proteome Res. 2018 Jan 5;17(1):63-75. doi: 10.1021/acs.jproteome.7b00329. Epub 2017 Nov 22.
Mass spectrometry data entry: PXD006095 , PXD006096
11 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
12 Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. Mol Cell Proteomics. 2023 Jan;22(1):100455. doi: 10.1016/j.mcpro.2022.100455. Epub 2022 Nov 24.
Mass spectrometry data entry: PXD036569
13 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
14 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
15 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
16 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
17 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
18 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
19 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
20 A Photoaffinity Displacement Assay and Probes to Study the Cyclin-Dependent Kinase Family. Angew Chem Int Ed Engl. 2019 Nov 25;58(48):17322-17327. doi: 10.1002/anie.201906321. Epub 2019 Oct 31.
21 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
22 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.