General Information of Experiment

Probe Name Probe 12  Probe Info 
Probe concentration 10 uM
Criteria Other data
Competitor Name Compound 9  Competitor Info 
Competitor Concentration 200 uM
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Peripheral blood
Disease Model Acute myeloid leukemia [ICD-11:2A60]
Model Name Human acute myeloid leukemia cell lysate (HL-60)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 18 Protein Related to This Bioclass
Target ID Target Name
 LDTP09285  Atypical kinase COQ8A, mitochondrial (COQ8A)
 LDTP10779  Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2)
 LDTP06023  Calcium/calmodulin-dependent protein kinase type 1 (CAMK1)
 LDTP05920  Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G)
 LDTP12852  Cyclin-dependent kinase 12 (CDK12)
 LDTP03299  Cyclin-dependent kinase 2 (CDK2)
 LDTP05245  Cyclin-dependent kinase 5 (CDK5)
 LDTP04379  Cyclin-dependent kinase 7 (CDK7)
 LDTP04384  Cyclin-dependent kinase 9 (CDK9)
 LDTP00497  Cyclin-G-associated kinase (GAK)
 LDTP05953  Dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A)
 LDTP03445  Mitogen-activated protein kinase 1 (MAPK1)
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT)
 LDTP01704  Phosphatidylserine lipase ABHD16A (ABHD16A)
 LDTP06100  Protein-tyrosine kinase 2-beta (PTK2B)
 LDTP06384  Ribosomal protein S6 kinase alpha-1 (RPS6KA1)
 LDTP01664  Serine/threonine-protein kinase OSR1 (OXSR1)
 LDTP10809  SRSF protein kinase 1 (SRPK1)
Other
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name
 LDTP10873  Prefoldin subunit 5 (PFDN5)

References

1 A Photoaffinity Displacement Assay and Probes to Study the Cyclin-Dependent Kinase Family. Angew Chem Int Ed Engl. 2019 Nov 25;58(48):17322-17327. doi: 10.1002/anie.201906321. Epub 2019 Oct 31.