Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name FFF probe11  Probe Info 
Probe concentration Probe:200uM; negative probe:200uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
SILAC
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Chronic myeloid leukemia [ICD-11:2A20]
Model Name Human chronic myeloid leukemia cells (K562)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 294 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12639  1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) 20.0
 LDTP05476  3-ketodihydrosphingosine reductase (KDSR) 20.0
 LDTP10322  Abasic site processing protein HMCES (HMCES) 20.0
 LDTP00968  Acyl-CoA (8-3)-desaturase (FADS1) 20.0
 LDTP06894  Acyl-coenzyme A synthetase ACSM3, mitochondrial (ACSM3) 20.0
 LDTP12415  Adenosine 5'-monophosphoramidase HINT3 (HINT3) 20.0
 LDTP10394  Adenosylhomocysteinase 3 (AHCYL2) 20.0
 LDTP11127  ADP-dependent glucokinase (ADPGK) 20.0
 LDTP14075  AFG3-like protein 2 (AFG3L2) 20.0
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 20.0
 LDTP09251  Atlastin-2 (ATL2) 20.0
 LDTP10848  ATP-dependent zinc metalloprotease YME1L1 (YME1L1) 20.0
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 20.0
 LDTP07154  ATPase family AAA domain-containing protein 3B (ATAD3B) 20.0
 LDTP00836  ATPase GET3 (GET3) 20.0
 LDTP09285  Atypical kinase COQ8A, mitochondrial (COQ8A) 20.0
 LDTP10201  Atypical kinase COQ8B, mitochondrial (COQ8B) 20.0
 LDTP04358  Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) 20.0
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 20.0
 LDTP03145  Catechol O-methyltransferase (COMT) 20.0
 LDTP02198  Cathepsin D (CTSD) 20.0
 LDTP10331  Cilia- and flagella-associated protein 36 (CFAP36) 20.0
 LDTP12048  Complex I assembly factor ACAD9, mitochondrial (ACAD9) 20.0
 LDTP00697  Cytochrome b5 type B (CYB5B) 20.0
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2) 20.0
 LDTP11723  Cytosolic 5'-nucleotidase 3A (NT5C3A) 20.0
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 20.0
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 20.0
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 20.0
 LDTP11225  Deoxyhypusine hydroxylase (DOHH) 20.0
 LDTP10466  Deubiquitinating protein VCPIP1 (VCPIP1) 20.0
 LDTP19892  DGAT1/2-independent enzyme synthesizing storage lipids (TMEM68) 20.0
 LDTP00577  Dihydroxyacetone phosphate acyltransferase (GNPAT) 20.0
 LDTP04273  DNA primase large subunit (PRIM2) 20.0
 LDTP03298  DNA-directed RNA polymerase II subunit RPB1 (POLR2A) 20.0
 LDTP01047  Dolichol-phosphate mannosyltransferase subunit 1 (DPM1) 20.0
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 20.0
 LDTP14214  Dolichyl-phosphate beta-glucosyltransferase (ALG5) 20.0
 LDTP05447  Dynamin-1 (DNM1) 20.0
 LDTP12757  E3 ubiquitin-protein ligase MARCHF5 (MARCHF5) 20.0
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 20.0
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 20.0
 LDTP09063  Estradiol 17-beta-dehydrogenase 11 (HSD17B11) 20.0
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 20.0
 LDTP01634  Fatty acid CoA ligase Acsl3 (ACSL3) 20.0
 LDTP03628  Glycerol kinase (GK) 20.0
 LDTP08232  Glycerol-3-phosphate acyltransferase 4 (GPAT4) 20.0
 LDTP12233  Helicase MOV-10 (MOV10) 20.0
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 20.0
 LDTP04531  Hexokinase-2 (HK2) 20.0
 LDTP08352  Histone-arginine methyltransferase CARM1 (CARM1) 20.0
 LDTP04581  Holocytochrome c-type synthase (HCCS) 20.0
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 20.0
 LDTP01333  Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) 20.0
 LDTP04211  Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) 20.0
 LDTP04519  Kinesin-like protein KIF11 (KIF11) 20.0
 LDTP12105  L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) 20.0
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 20.0
 LDTP02385  Leukotriene A-4 hydrolase (LTA4H) 20.0
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 20.0
 LDTP10930  Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) 20.0
 LDTP09396  Minor histocompatibility antigen H13 (HM13) 20.0
 LDTP06810  Mitochondrial import inner membrane translocase subunit TIM50 (TIMM50) 20.0
 LDTP08596  Mitochondrial Rho GTPase 2 (RHOT2) 20.0
 LDTP10038  Mitochondrial ubiquitin ligase activator of NFKB 1 (MUL1) 20.0
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 20.0
 LDTP01503  Mitofusin-2 (MFN2) 20.0
 LDTP01561  NADH dehydrogenase 1 alpha subcomplex subunit 10, mitochondrial (NDUFA10) 20.0
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 20.0
 LDTP01743  NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) 20.0
 LDTP01514  NADH dehydrogenase 1 beta subcomplex subunit 4 (NDUFB4) 20.0
 LDTP01515  NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial (NDUFB8) 20.0
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 20.0
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 20.0
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 20.0
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 20.0
 LDTP10077  Patatin-like phospholipase domain-containing protein 2 (PNPLA2) 20.0
 LDTP13989  Peptidyl-tRNA hydrolase 2, mitochondrial (PTRH2) 20.0
 LDTP06307  Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) 20.0
 LDTP12608  Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) 20.0
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 20.0
 LDTP11284  Phosphatidylserine synthase 2 (PTDSS2) 20.0
 LDTP05623  Polypeptide N-acetylgalactosaminyltransferase 2 (GALNT2) 20.0
 LDTP08859  Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) 20.0
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 20.0
 LDTP07003  Presequence protease, mitochondrial (PITRM1) 20.0
 LDTP05373  Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1) 20.0
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 20.0
 LDTP00988  Protein O-GlcNAcase (OGA) 20.0
 LDTP15370  Pseudouridylate synthase RPUSD2 (RPUSD2) 20.0
 LDTP04992  Ras-related protein Rab-11A (RAB11A) 20.0
 LDTP06501  Ras-related protein Rab-11B (RAB11B) 20.0
 LDTP10020  Ras-related protein Rab-24 (RAB24) 20.0
 LDTP09666  Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) 20.0
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 20.0
 LDTP12180  Retinol dehydrogenase 14 (RDH14) 20.0
 LDTP00890  S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) 20.0
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 20.0
 LDTP09976  Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (ATP2A3) 20.0
 LDTP03730  Sepiapterin reductase (SPR) 20.0
 LDTP00597  Serine palmitoyltransferase 1 (SPTLC1) 20.0
 LDTP05779  Serine/threonine-protein kinase 3 (STK3) 20.0
 LDTP05733  Serine/threonine-protein kinase 4 (STK4) 20.0
 LDTP00422  Serine/threonine-protein kinase Chk1 (CHEK1) 20.0
 LDTP11299  Serine/threonine-protein kinase RIO2 (RIOK2) 20.0
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 20.0
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 20.0
 LDTP06142  Squalene monooxygenase (SQLE) 20.0
 LDTP03842  Squalene synthase (FDFT1) 20.0
 LDTP00344  Stearoyl-CoA desaturase (SCD) 20.0
 LDTP06455  Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (NSDHL) 20.0
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) 20.0
 LDTP12056  Thiol S-methyltransferase TMT1A (TMT1A) 20.0
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 20.0
 LDTP00399  Torsin-1A (TOR1A) 20.0
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) 20.0
 LDTP15250  tRNA (guanine(10)-N2)-methyltransferase homolog (TRMT11) 20.0
 LDTP05074  Tubulin alpha-1B chain (TUBA1B) 20.0
 LDTP11074  Tubulin alpha-1C chain (TUBA1C) 20.0
 LDTP05075  Tubulin alpha-4A chain (TUBA4A) 20.0
 LDTP12810  Tubulin alpha-8 chain (TUBA8) 20.0
 LDTP10374  Unconventional myosin-XIX (MYO19) 20.0
 LDTP04289  Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) 20.0
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 20.0
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 20.0
 LDTP14231  GTP-binding protein SAR1b (SAR1B) 20.0
 LDTP01704  Phosphatidylserine lipase ABHD16A (ABHD16A) 19.6
 LDTP07227  Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) 19.2
 LDTP01770  NADH-cytochrome b5 reductase 3 (CYB5R3) 19.0
 LDTP03592  Ribonucleoside-diphosphate reductase subunit M2 (RRM2) 19.0
 LDTP12163  Calcyclin-binding protein (CACYBP) 19.0
 LDTP02283  Cytochrome c1, heme protein, mitochondrial (CYC1) 18.1
 LDTP10495  Ubiquitin carboxyl-terminal hydrolase 47 (USP47) 18.0
 LDTP00950  Dynamin-like 120 kDa protein, mitochondrial (OPA1) 17.3
 LDTP09388  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (STT3B) 17.2
 LDTP12470  GTP-binding protein SAR1a (SAR1A) 16.5
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 16.4
 LDTP02935  Tyrosine-protein phosphatase non-receptor type 1 (PTPN1) 16.2
 LDTP07362  Atlastin-3 (ATL3) 16.0
 LDTP04619  5'-AMP-activated protein kinase subunit gamma-1 (PRKAG1) 15.7
 LDTP00496  Long-chain fatty acid transport protein 2 (SLC27A2) 15.5
 LDTP02493  Serine/threonine-protein kinase A-Raf (ARAF) 15.2
 LDTP06618  ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) 15.2
 LDTP03610  Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) 15.0
 LDTP00186  Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) 14.6
 LDTP02679  Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) 14.6
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 14.3
 LDTP01168  NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) 14.2
 LDTP06905  Acylglycerol kinase, mitochondrial (AGK) 13.8
 LDTP02231  Tyrosine-protein kinase Yes (YES1) 13.7
 LDTP13285  Probable ATP-dependent RNA helicase DDX20 (DDX20) 13.6
 LDTP00982  Long-chain-fatty-acid--CoA ligase 4 (ACSL4) 13.6
 LDTP03424  ATP-binding cassette sub-family D member 3 (ABCD3) 13.6
 LDTP04032  Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2) 13.0
 LDTP14019  HBS1-like protein (HBS1L) 12.9
 LDTP10987  Tumor susceptibility gene 101 protein (TSG101) 12.8
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 12.7
 LDTP03163  Sterol carrier protein 2 (SCP2) 12.7
 LDTP01768  Glutamate dehydrogenase 1, mitochondrial (GLUD1) 12.5
 LDTP02942  ADP-ribosylation factor 4 (ARF4) 12.4
 LDTP14074  Ribosomal biogenesis protein LAS1L (LAS1L) 12.3
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 12.1
 LDTP07762  Hydroxysteroid dehydrogenase-like protein 2 (HSDL2) 11.9
 LDTP05193  ADP-ribosylation factor 5 (ARF5) 11.8
 LDTP04456  Ubiquitin carboxyl-terminal hydrolase 11 (USP11) 11.8
 LDTP04248  Deoxyhypusine synthase (DHPS) 11.7
 LDTP17247  5'-nucleotidase domain-containing protein 1 (NT5DC1) 11.6
 LDTP03726  Replication factor C subunit 2 (RFC2) 11.4
 LDTP04183  Lanosterol synthase (LSS) 11.3
 LDTP02169  Beta-hexosaminidase subunit alpha (HEXA) 11.1
 LDTP04892  Ras-related protein Rab-2A (RAB2A) 11.1
 LDTP03418  Proteasome subunit beta type-6 (PSMB6) 10.9
 LDTP00294  26S proteasome non-ATPase regulatory subunit 14 (PSMD14) 10.9
 LDTP04895  Ras-related protein Rab-10 (RAB10) 10.8
 LDTP06104  Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8) 10.8
 LDTP10862  Proteasome subunit beta type-7 (PSMB7) 10.8
 LDTP04440  Peroxisomal multifunctional enzyme type 2 (HSD17B4) 10.8
 LDTP05192  ADP-ribosylation factor 1 (ARF1) 10.7
 LDTP04907  ADP-ribosylation factor 3 (ARF3) 10.7
 LDTP00314  ATP-dependent RNA helicase DDX3X (DDX3X) 10.5
 LDTP10318  Ubiquitin thioesterase OTUB1 (OTUB1) 10.4
 LDTP05006  Ras-related protein Rab-1A (RAB1A) 10.2
 LDTP11733  Ras-related protein Rab-1B (RAB1B) 10.2
 LDTP03518  Enoyl-CoA hydratase, mitochondrial (ECHS1) 10.2
 LDTP04374  Dynamin-2 (DNM2) 10.1
 LDTP04144  Cytochrome b-c1 complex subunit Rieske, mitochondrial (UQCRFS1) 10.1
 LDTP11788  EH domain-containing protein 4 (EHD4) 9.8
 LDTP12312  Ras-related protein Rab-18 (RAB18) 9.8
 LDTP02188  Protein disulfide-isomerase (P4HB) 9.8
 LDTP03900  ADP-ribosylation factor-like protein 1 (ARL1) 9.7
 LDTP02149  Cyclin-dependent kinase 1 (CDK1) 9.6
 LDTP11187  COP9 signalosome complex subunit 4 (COPS4) 9.5
 LDTP12610  Obg-like ATPase 1 (OLA1) 9.5
 LDTP02995  NADH dehydrogenase flavoprotein 2, mitochondrial (NDUFV2) 9.4
 LDTP04243  Fatty acid synthase (FASN) 9.4
 LDTP03060  Proteasome subunit beta type-1 (PSMB1) 9.3
 LDTP06612  2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (DECR1) 9.2
 LDTP02837  Beta-galactosidase (GLB1) 9.0
 LDTP09044  ATPase family gene 2 protein homolog A (AFG2A) 8.6
 LDTP03537  Glycylpeptide N-tetradecanoyltransferase 1 (NMT1) 8.5
 LDTP03552  Pyruvate kinase PKLR (PKLR) 8.4
 LDTP02557  Ras-related protein Ral-A (RALA) 8.3
 LDTP01220  Mitochondrial-processing peptidase subunit beta (PMPCB) 8.2
 LDTP03572  Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA) 8.2
 LDTP02150  ATP synthase subunit beta, mitochondrial (ATP5F1B) 8.2
 LDTP06199  Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D) 8.2
 LDTP04901  Ras-related protein Rab-14 (RAB14) 8.2
 LDTP02232  Tyrosine-protein kinase Lyn (LYN) 8.2
 LDTP02922  CTP synthase 1 (CTPS1) 8.0
 LDTP05478  Tyrosine-protein kinase BTK (BTK) 8.0
 LDTP10780  Trimethylguanosine synthase (TGS1) 7.8
 LDTP03753  Cystathionine beta-synthase (CBS) 7.8
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 7.8
 LDTP06338  Prostaglandin E synthase 3 (PTGES3) 7.8
 LDTP04310  E3 SUMO-protein ligase RanBP2 (RANBP2) 7.7
 LDTP02798  NAD(P)H dehydrogenase [quinone] 1 (NQO1) 7.7
 LDTP08947  eEF1A lysine and N-terminal methyltransferase (METTL13) 7.7
 LDTP03189  Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) 7.7
 LDTP06150  DNA replication licensing factor MCM6 (MCM6) 7.7
 LDTP01444  E3 UFM1-protein ligase 1 (UFL1) 7.5
 LDTP10500  Lymphokine-activated killer T-cell-originated protein kinase (PBK) 7.5
 LDTP05920  Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G) 7.3
 LDTP03817  Lon protease homolog, mitochondrial (LONP1) 7.2
 LDTP09899  Probable ATP-dependent RNA helicase DDX17 (DDX17) 7.2
 LDTP04384  Cyclin-dependent kinase 9 (CDK9) 7.2
 LDTP05244  Cyclin-dependent kinase 6 (CDK6) 7.2
 LDTP05436  Aldo-keto reductase family 1 member C1 (AKR1C1) 7.0
 LDTP03401  Multifunctional protein CAD (CAD) 7.0
 LDTP02356  2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) 7.0
 LDTP04890  Signal recognition particle subunit SRP54 (SRP54) 7.0
 LDTP02925  ATP-dependent 6-phosphofructokinase, liver type (PFKL) 7.0
 LDTP15484  Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) 7.0
 LDTP02924  Probable ATP-dependent RNA helicase DDX5 (DDX5) 6.9
 LDTP02602  Histidine--tRNA ligase, cytoplasmic (HARS1) 6.9
 LDTP04962  26S proteasome regulatory subunit 4 (PSMC1) 6.9
 LDTP00479  Histone acetyltransferase type B catalytic subunit (HAT1) 6.8
 LDTP01245  Enoyl-CoA delta isomerase 2 (ECI2) 6.8
 LDTP02991  Hexokinase-1 (HK1) 6.8
 LDTP11107  Serine/threonine-protein phosphatase CPPED1 (CPPED1) 6.7
 LDTP04911  Ras-related protein Rap-2b (RAP2B) 6.7
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 6.6
 LDTP12673  4'-phosphopantetheine phosphatase (PANK4) 6.6
 LDTP06067  Tubulin--tyrosine ligase-like protein 12 (TTLL12) 6.5
 LDTP00886  Nardilysin (NRDC) 6.5
 LDTP12586  Phenylalanine--tRNA ligase beta subunit (FARSB) 6.3
 LDTP05588  RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) 6.3
 LDTP13995  Ras-related protein Rap-2c (RAP2C) 6.3
 LDTP03944  Tyrosine-protein kinase CSK (CSK) 6.3
 LDTP06192  Neutral alpha-glucosidase AB (GANAB) 6.2
 LDTP04878  Eukaryotic initiation factor 4A-I (EIF4A1) 6.2
 LDTP06089  Eukaryotic initiation factor 4A-II (EIF4A2) 6.1
 LDTP02362  Dihydrolipoyl dehydrogenase, mitochondrial (DLD) 6.1
 LDTP02733  Pyruvate kinase PKM (PKM) 6.1
 LDTP03413  Proteasome subunit alpha type-5 (PSMA5) 6.0
 LDTP01766  L-lactate dehydrogenase A chain (LDHA) 6.0
 LDTP03770  Alpha-adducin (ADD1) 6.0
 LDTP12597  BMP-2-inducible protein kinase (BMP2K) 6.0
 LDTP03299  Cyclin-dependent kinase 2 (CDK2) 6.0
 LDTP05046  Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PPP2R2A) 6.0
 LDTP13251  DNA dC->dU-editing enzyme APOBEC-3B (APOBEC3B) 5.9
 LDTP03433  NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (NDUFS1) 5.9
 LDTP02783  Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCHL3) 5.9
 LDTP11494  Neurolysin, mitochondrial (NLN) 5.9
 LDTP07946  ATP-dependent RNA helicase DHX30 (DHX30) 5.8
 LDTP05007  GTP-binding nuclear protein Ran (RAN) 5.8
 LDTP10887  Synaptic vesicle membrane protein VAT-1 homolog (VAT1) 5.7
 LDTP06427  Translin (TSN) 5.7
 LDTP04646  Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1) 5.7
 LDTP05838  RING-type E3 ubiquitin-protein ligase PPIL2 (PPIL2) 5.7
 LDTP05064  Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) 5.7
 LDTP04876  Actin, cytoplasmic 1 (ACTB) 5.6
 LDTP03146  Protein-glutamine gamma-glutamyltransferase 2 (TGM2) 5.6
 LDTP02611  Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) 5.5
 LDTP16040  Glyoxalase domain-containing protein 4 (GLOD4) 5.5
 LDTP13787  RuvB-like 2 (RUVBL2) 5.5
 LDTP06190  Ubiquitin carboxyl-terminal hydrolase 10 (USP10) 5.5
 LDTP09962  Ubiquitin carboxyl-terminal hydrolase 7 (USP7) 5.5
 LDTP00714  26S proteasome non-ATPase regulatory subunit 3 (PSMD3) 5.5
 LDTP03682  DNA replication licensing factor MCM7 (MCM7) 5.4
 LDTP07581  Aspartate--tRNA ligase, mitochondrial (DARS2) 5.4
 LDTP13831  Phenylalanine--tRNA ligase alpha subunit (FARSA) 5.4
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS) 5.4
 LDTP07651  Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) 5.4
 LDTP00931  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5) 5.4
 LDTP06532  26S proteasome non-ATPase regulatory subunit 5 (PSMD5) 5.3
 LDTP04963  26S proteasome regulatory subunit 8 (PSMC5) 5.2
 LDTP08979  Prostaglandin reductase 2 (PTGR2) 5.2
 LDTP08687  tRNA (uracil-5-)-methyltransferase homolog A (TRMT2A) 5.1
 LDTP05069  Actin, alpha cardiac muscle 1 (ACTC1) 5.1
 LDTP05073  Actin, alpha skeletal muscle (ACTA1) 5.1
 LDTP04999  Actin, aortic smooth muscle (ACTA2) 5.1
 LDTP12688  ATP-dependent RNA helicase DDX18 (DDX18) 5.1
 LDTP12835  Large ribosomal subunit protein mL39 (MRPL39) 5.0
 LDTP03680  DNA replication licensing factor MCM4 (MCM4) 5.0
Transporter and channel
Click to Show/Hide to Show 147 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11116  45 kDa calcium-binding protein (SDF4) 20.0
 LDTP02608  ADP/ATP translocase 1 (SLC25A4) 20.0
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 20.0
 LDTP12704  Anoctamin-10 (ANO10) 20.0
 LDTP01936  Apolipoprotein E (APOE) 20.0
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 20.0
 LDTP08030  Autophagy-related protein 9A (ATG9A) 20.0
 LDTP04426  B-cell receptor-associated protein 31 (BCAP31) 20.0
 LDTP10036  BOS complex subunit NCLN (NCLN) 20.0
 LDTP07361  Bridge-like lipid transfer protein family member 3A (BLTP3A) 20.0
 LDTP03405  Calnexin (CANX) 20.0
 LDTP10804  Chloride channel CLIC-like protein 1 (CLCC1) 20.0
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 20.0
 LDTP02815  Desmoplakin (DSP) 20.0
 LDTP01301  Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (SLC25A12) 20.0
 LDTP13393  Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) 20.0
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 20.0
 LDTP01366  Flotillin-1 (FLOT1) 20.0
 LDTP15064  G-protein coupled receptor-associated protein LMBRD2 (LMBRD2) 20.0
 LDTP09333  Golgin subfamily A member 5 (GOLGA5) 20.0
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 20.0
 LDTP01574  Importin-7 (IPO7) 20.0
 LDTP00630  Importin-8 (IPO8) 20.0
 LDTP10769  Intermembrane lipid transfer protein VPS13A (VPS13A) 20.0
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) 20.0
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 20.0
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 20.0
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 20.0
 LDTP05900  Metaxin-1 (MTX1) 20.0
 LDTP11250  MICOS complex subunit MIC26 (APOO) 20.0
 LDTP06660  MICOS complex subunit MIC60 (IMMT) 20.0
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 20.0
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 20.0
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 20.0
 LDTP04956  Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) 20.0
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 20.0
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 20.0
 LDTP19379  Mitochondrial import inner membrane translocase subunit Tim23B (TIMM23B) 20.0
 LDTP00821  Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) 20.0
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 20.0
 LDTP14200  Mitochondrial ornithine transporter 1 (SLC25A15) 20.0
 LDTP12644  Mitochondrial potassium channel ATP-binding subunit (ABCB8) 20.0
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 20.0
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 20.0
 LDTP09278  Multiple coagulation factor deficiency protein 2 (MCFD2) 20.0
 LDTP03777  Nuclear pore complex protein Nup214 (NUP214) 20.0
 LDTP11213  Nucleoporin NDC1 (NDC1) 20.0
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 20.0
 LDTP06331  Pericentriolar material 1 protein (PCM1) 20.0
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 20.0
 LDTP02215  Prosaposin (PSAP) 20.0
 LDTP04237  Protein ERGIC-53 (LMAN1) 20.0
 LDTP13164  Protein sel-1 homolog 1 (SEL1L) 20.0
 LDTP07610  Proton-coupled zinc antiporter SLC30A9, mitochondrial (SLC30A9) 20.0
 LDTP12207  Putative divalent cation/proton antiporter TMEM165 (TMEM165) 20.0
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 20.0
 LDTP07531  Sideroflexin-4 (SFXN4) 20.0
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 20.0
 LDTP14084  Sorting and assembly machinery component 50 homolog (SAMM50) 20.0
 LDTP08344  Stimulator of interferon genes protein (STING1) 20.0
 LDTP05934  Stromal interaction molecule 1 (STIM1) 20.0
 LDTP01454  SUN domain-containing protein 1 (SUN1) 20.0
 LDTP13256  SUN domain-containing protein 2 (SUN2) 20.0
 LDTP00857  Syntaxin-6 (STX6) 20.0
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 20.0
 LDTP15838  Translocation protein SEC62 (SEC62) 20.0
 LDTP13243  Translocation protein SEC63 homolog (SEC63) 20.0
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 20.0
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 20.0
 LDTP09789  Transmembrane 9 superfamily member 4 (TM9SF4) 20.0
 LDTP05875  Transmembrane emp24 domain-containing protein 1 (TMED1) 20.0
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 20.0
 LDTP15948  Transmembrane protein 126A (TMEM126A) 20.0
 LDTP07477  Transmembrane protein 214 (TMEM214) 20.0
 LDTP11229  Transmembrane protein 70, mitochondrial (TMEM70) 20.0
 LDTP15481  Transmembrane protein 87A (TMEM87A) 20.0
 LDTP12695  Trimeric intracellular cation channel type B (TMEM38B) 20.0
 LDTP12533  Ubiquilin-4 (UBQLN4) 20.0
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 20.0
 LDTP10343  Vacuole membrane protein 1 (VMP1) 20.0
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 20.0
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 20.0
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 20.0
 LDTP06462  Neutral amino acid transporter B(0) (SLC1A5) 19.5
 LDTP12090  Sideroflexin-1 (SFXN1) 19.1
 LDTP02087  ADP/ATP translocase 2 (SLC25A5) 18.6
 LDTP01969  Transferrin receptor protein 1 (TFRC) 18.2
 LDTP00014  Extended synaptotagmin-2 (ESYT2) 17.9
 LDTP00592  Surfeit locus protein 4 (SURF4) 17.6
 LDTP04553  Tricarboxylate transport protein, mitochondrial (SLC25A1) 16.7
 LDTP04213  Phosphatidylinositol transfer protein beta isoform (PITPNB) 16.5
 LDTP02547  Protein 4.1 (EPB41) 16.4
 LDTP13953  Endophilin-B1 (SH3GLB1) 16.4
 LDTP11291  Transmembrane emp24 domain-containing protein 9 (TMED9) 16.3
 LDTP12510  Aladin (AAAS) 15.7
 LDTP04787  Transmembrane protein 33 (TMEM33) 15.5
 LDTP07002  Transport and Golgi organization protein 1 homolog (MIA3) 15.1
 LDTP03870  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST) 14.4
 LDTP05238  Solute carrier family 25 member 3 (SLC25A3) 13.8
 LDTP01234  Erlin-1 (ERLIN1) 13.5
 LDTP01455  Erlin-2 (ERLIN2) 13.3
 LDTP12517  ATP-binding cassette sub-family B member 10, mitochondrial (ABCB10) 12.3
 LDTP09502  Nuclear pore membrane glycoprotein 210 (NUP210) 12.3
 LDTP05690  Vesicular integral-membrane protein VIP36 (LMAN2) 12.1
 LDTP04393  Annexin A11 (ANXA11) 12.0
 LDTP05017  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1) 11.9
 LDTP09202  Nucleoporin Nup43 (NUP43) 11.6
 LDTP02058  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) 10.5
 LDTP03717  Prohibitin 1 (PHB1) 10.1
 LDTP00262  Acetyl-coenzyme A transporter 1 (SLC33A1) 10.0
 LDTP10069  Exocyst complex component 4 (EXOC4) 10.0
 LDTP05020  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2) 9.9
 LDTP05384  Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) 9.6
 LDTP01043  Sorting nexin-2 (SNX2) 9.6
 LDTP01748  Mitochondrial import receptor subunit TOM40 homolog (TOMM40) 9.4
 LDTP04662  Exportin-2 (CSE1L) 9.2
 LDTP14509  ATP synthase subunit d, mitochondrial (ATP5PD) 9.1
 LDTP11531  Oxysterol-binding protein-related protein 8 (OSBPL8) 9.0
 LDTP03839  Nuclear pore glycoprotein p62 (NUP62) 8.6
 LDTP01180  Programmed cell death protein 6 (PDCD6) 8.6
 LDTP08769  Nuclear pore complex protein Nup93 (NUP93) 8.5
 LDTP13416  Stomatin-like protein 2, mitochondrial (STOML2) 8.3
 LDTP02057  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) 8.0
 LDTP11161  Extended synaptotagmin-1 (ESYT1) 8.0
 LDTP08029  Nucleoporin p54 (NUP54) 7.6
 LDTP01295  Nuclear pore complex protein Nup155 (NUP155) 7.5
 LDTP13661  Sorting nexin-6 (SNX6) 7.5
 LDTP00434  Transportin-2 (TNPO2) 7.3
 LDTP05938  Sorting nexin-1 (SNX1) 7.2
 LDTP14133  Transportin-3 (TNPO3) 7.0
 LDTP09949  Transportin-1 (TNPO1) 6.6
 LDTP06549  Hsp90 co-chaperone Cdc37 (CDC37) 6.3
 LDTP00865  Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) 6.1
 LDTP01601  Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) 6.1
 LDTP14066  Hypoxia up-regulated protein 1 (HYOU1) 6.1
 LDTP02959  Protein SON (SON) 5.8
 LDTP09515  Importin-4 (IPO4) 5.7
 LDTP10663  Importin-9 (IPO9) 5.7
 LDTP04800  Nuclear pore complex protein Nup107 (NUP107) 5.6
 LDTP04597  Methylosome subunit pICln (CLNS1A) 5.6
 LDTP11310  Nuclear pore complex protein Nup85 (NUP85) 5.6
 LDTP04707  Protein SEC13 homolog (SEC13) 5.5
 LDTP03327  ATP synthase subunit alpha, mitochondrial (ATP5F1A) 5.5
 LDTP04501  Importin subunit alpha-1 (KPNA2) 5.4
 LDTP09825  Nuclear pore complex protein Nup205 (NUP205) 5.2
 LDTP03664  Kinesin-1 heavy chain (KIF5B) 5.2
 LDTP18526  ATP-binding cassette sub-family F member 2 (ABCF2) 5.0
Transcription factor
Click to Show/Hide to Show 10 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 20.0
 LDTP02016  Glucocorticoid receptor (NR3C1) 20.0
 LDTP02879  Zinc finger protein 24 (ZNF24) 20.0
 LDTP05065  Y-box-binding protein 1 (YBX1) 15.4
 LDTP06341  Non-POU domain-containing octamer-binding protein (NONO) 7.3
 LDTP03212  Splicing factor, proline- and glutamine-rich (SFPQ) 6.4
 LDTP03903  Signal transducer and activator of transcription 3 (STAT3) 6.0
 LDTP03971  Signal transducer and activator of transcription 5A (STAT5A) 6.0
 LDTP04454  Signal transducer and activator of transcription 5B (STAT5B) 5.9
 LDTP10891  DnaJ homolog subfamily C member 2 (DNAJC2) 5.6
Immunoglobulin
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP14203  Junctional adhesion molecule A (F11R) 17.4
Cytokine and receptor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05757  Protein Red (IK) 5.6
Other
Click to Show/Hide to Show 262 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15434  ADP-ribosylation factor-like protein 6-interacting protein 6 (ARL6IP6) 20.0
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 20.0
 LDTP08682  Ankyrin repeat domain-containing protein 13A (ANKRD13A) 20.0
 LDTP01600  BAG family molecular chaperone regulator 4 (BAG4) 20.0
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 20.0
 LDTP07598  BRCA1-associated ATM activator 1 (BRAT1) 20.0
 LDTP07234  BRO1 domain-containing protein BROX (BROX) 20.0
 LDTP16116  BSD domain-containing protein 1 (BSDC1) 20.0
 LDTP02128  Calbindin (CALB1) 20.0
 LDTP03590  cAMP-dependent protein kinase type II-beta regulatory subunit (PRKAR2B) 20.0
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 20.0
 LDTP12379  Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) 20.0
 LDTP05353  Desmoglein-1 (DSG1) 20.0
 LDTP11894  DnaJ homolog subfamily C member 5 (DNAJC5) 20.0
 LDTP04356  Emerin (EMD) 20.0
 LDTP02734  Endoplasmin (HSP90B1) 20.0
 LDTP07521  Enhancer of mRNA-decapping protein 4 (EDC4) 20.0
 LDTP10078  Far upstream element-binding protein 1 (FUBP1) 20.0
 LDTP09938  Far upstream element-binding protein 2 (KHSRP) 20.0
 LDTP10185  FAS-associated factor 2 (FAF2) 20.0
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 20.0
 LDTP11911  Golgi phosphoprotein 3 (GOLPH3) 20.0
 LDTP11910  Golgi phosphoprotein 3-like (GOLPH3L) 20.0
 LDTP07758  GRB10-interacting GYF protein 2 (GIGYF2) 20.0
 LDTP07318  HAUS augmin-like complex subunit 3 (HAUS3) 20.0
 LDTP02053  Heat shock protein beta-1 (HSPB1) 20.0
 LDTP00500  Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) 20.0
 LDTP03614  Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) 20.0
 LDTP00991  Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) 20.0
 LDTP11238  Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) 20.0
 LDTP17065  Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) 20.0
 LDTP03182  Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) 20.0
 LDTP08238  Kinectin (KTN1) 20.0
 LDTP09069  Kinetochore protein Spc24 (SPC24) 20.0
 LDTP07605  La-related protein 1 (LARP1) 20.0
 LDTP03967  Lamina-associated polypeptide 2, isoform alpha (TMPO) 20.0
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 20.0
 LDTP12395  Large ribosomal subunit protein mL40 (MRPL40) 20.0
 LDTP15863  Large ribosomal subunit protein mL45 (MRPL45) 20.0
 LDTP03557  Leukocyte elastase inhibitor (SERPINB1) 20.0
 LDTP09619  Limb region 1 protein homolog (LMBR1) 20.0
 LDTP14217  Lipid droplet-regulating VLDL assembly factor AUP1 (AUP1) 20.0
 LDTP14939  Membralin (TMEM259) 20.0
 LDTP07718  MICOS complex subunit MIC27 (APOOL) 20.0
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 20.0
 LDTP06277  Mortality factor 4-like protein 2 (MORF4L2) 20.0
 LDTP13630  Neudesin (NENF) 20.0
 LDTP05375  Nucleobindin-1 (NUCB1) 20.0
 LDTP05160  Nucleobindin-2 (NUCB2) 20.0
 LDTP09545  Nucleolar complex protein 3 homolog (NOC3L) 20.0
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 20.0
 LDTP16099  p53 and DNA damage-regulated protein 1 (PDRG1) 20.0
 LDTP10889  Perilipin-2 (PLIN2) 20.0
 LDTP11906  Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) 20.0
 LDTP14017  Plakophilin-3 (PKP3) 20.0
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 20.0
 LDTP10924  Prohibitin-2 (PHB2) 20.0
 LDTP02596  Proliferating cell nuclear antigen (PCNA) 20.0
 LDTP11176  Protein canopy homolog 3 (CNPY3) 20.0
 LDTP16080  Protein FAM114A2 (FAM114A2) 20.0
 LDTP10056  Protein FAM162A (FAM162A) 20.0
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 20.0
 LDTP08224  Protein LYRIC (MTDH) 20.0
 LDTP17214  Protein odr-4 homolog (ODR4) 20.0
 LDTP16156  Protein PALS2 (PALS2) 20.0
 LDTP19924  Protein PBDC1 (PBDC1) 20.0
 LDTP05277  Protein SET (SET) 20.0
 LDTP13430  Protein TASOR (TASOR) 20.0
 LDTP09851  Protein TFG (TFG) 20.0
 LDTP08130  Rab9 effector protein with kelch motifs (RABEPK) 20.0
 LDTP10849  Regulator of microtubule dynamics protein 3 (RMDN3) 20.0
 LDTP12729  Required for meiotic nuclear division protein 1 homolog (RMND1) 20.0
 LDTP06097  Reticulocalbin-2 (RCN2) 20.0
 LDTP01522  Reticulon-3 (RTN3) 20.0
 LDTP12412  Reticulon-4 (RTN4) 20.0
 LDTP05224  RNA-binding protein 10 (RBM10) 20.0
 LDTP17640  RNA-binding protein 12B (RBM12B) 20.0
 LDTP10684  RNA-binding protein 14 (RBM14) 20.0
 LDTP10832  RNA-binding protein 15 (RBM15) 20.0
 LDTP11046  RNA-binding protein 4B (RBM4B) 20.0
 LDTP05318  RNA-binding protein EWS (EWSR1) 20.0
 LDTP03775  RNA-binding protein FUS (FUS) 20.0
 LDTP10357  RUS family member 1 (RUSF1) 20.0
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 20.0
 LDTP06684  Sister chromatid cohesion protein PDS5 homolog A (PDS5A) 20.0
 LDTP00986  Syntaxin-10 (STX10) 20.0
 LDTP08389  Syntaxin-12 (STX12) 20.0
 LDTP13086  Syntaxin-18 (STX18) 20.0
 LDTP07368  Tetratricopeptide repeat protein 19, mitochondrial (TTC19) 20.0
 LDTP19963  TraB domain-containing protein (TRABD) 20.0
 LDTP16285  Transducin beta-like protein 2 (TBL2) 20.0
 LDTP14228  Transforming acidic coiled-coil-containing protein 3 (TACC3) 20.0
 LDTP18272  Transmembrane protein 209 (TMEM209) 20.0
 LDTP05998  Tubulin beta-2A chain (TUBB2A) 20.0
 LDTP11277  Tubulin beta-2B chain (TUBB2B) 20.0
 LDTP06809  Tubulin beta-8 chain (TUBB8) 20.0
 LDTP13626  Ubiquilin-1 (UBQLN1) 20.0
 LDTP13273  Ubiquilin-2 (UBQLN2) 20.0
 LDTP12025  UPF0488 protein C8orf33 (C8orf33) 20.0
 LDTP02297  Vimentin (VIM) 20.0
 LDTP12623  Zinc finger CCHC domain-containing protein 3 (ZCCHC3) 20.0
 LDTP06060  Ubiquitin-associated protein 2-like (UBAP2L) 19.8
 LDTP16814  Melanoma-associated antigen C1 (MAGEC1) 19.7
 LDTP10282  DnaJ homolog subfamily A member 3, mitochondrial (DNAJA3) 19.6
 LDTP02205  Tubulin beta chain (TUBB) 19.5
 LDTP04094  Large proline-rich protein BAG6 (BAG6) 19.0
 LDTP14136  Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13) 18.9
 LDTP10408  Far upstream element-binding protein 3 (FUBP3) 18.7
 LDTP03841  Hippocalcin-like protein 1 (HPCAL1) 18.1
 LDTP05904  Tubulin beta-3 chain (TUBB3) 18.0
 LDTP05076  Tubulin beta-4B chain (TUBB4B) 17.9
 LDTP02037  Tubulin beta-4A chain (TUBB4A) 17.8
 LDTP10947  Ataxin-2 (ATXN2) 17.6
 LDTP11233  Tubulin beta-6 chain (TUBB6) 17.5
 LDTP11324  RNA-binding protein 4 (RBM4) 17.2
 LDTP01206  Vesicle-trafficking protein SEC22b (SEC22B) 16.8
 LDTP09881  TATA-binding protein-associated factor 2N (TAF15) 16.8
 LDTP10209  Regulator of microtubule dynamics protein 1 (RMDN1) 16.6
 LDTP11978  HAUS augmin-like complex subunit 4 (HAUS4) 16.4
 LDTP08793  Armadillo repeat-containing protein 10 (ARMC10) 16.4
 LDTP04495  Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) 16.2
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) 16.2
 LDTP00756  Heterogeneous nuclear ribonucleoprotein R (HNRNPR) 16.1
 LDTP04652  Eukaryotic translation initiation factor 5 (EIF5) 16.1
 LDTP08500  Nostrin (NOSTRIN) 16.1
 LDTP04714  Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) 15.6
 LDTP06032  Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) 15.5
 LDTP14272  Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) 15.5
 LDTP10965  Nucleosome assembly protein 1-like 4 (NAP1L4) 15.4
 LDTP01259  Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PRKRA) 15.1
 LDTP05035  Growth factor receptor-bound protein 2 (GRB2) 15.0
 LDTP12476  Translation initiation factor eIF2B subunit gamma (EIF2B3) 15.0
 LDTP01920  Hemoglobin subunit zeta (HBZ) 14.9
 LDTP05767  TAR DNA-binding protein 43 (TARDBP) 14.7
 LDTP03606  DnaJ homolog subfamily A member 1 (DNAJA1) 14.5
 LDTP04684  Nucleosome assembly protein 1-like 1 (NAP1L1) 14.2
 LDTP05768  Heterogeneous nuclear ribonucleoprotein A0 (HNRNPA0) 14.1
 LDTP03850  RNA-binding motif protein, X chromosome (RBMX) 13.7
 LDTP03325  DnaJ homolog subfamily B member 1 (DNAJB1) 13.7
 LDTP00887  Calumenin (CALU) 13.6
 LDTP10700  KH domain-containing RNA-binding protein QKI (QKI) 13.5
 LDTP13591  A-kinase anchor protein 8-like (AKAP8L) 13.1
 LDTP09950  Rho guanine nucleotide exchange factor 2 (ARHGEF2) 13.0
 LDTP06879  Protein FAM98B (FAM98B) 12.4
 LDTP11138  Protein pelota homolog (PELO) 12.4
 LDTP01661  Synaptosomal-associated protein 29 (SNAP29) 12.4
 LDTP06413  Microtubule-associated protein RP/EB family member 2 (MAPRE2) 12.3
 LDTP12677  DnaJ homolog subfamily C member 11 (DNAJC11) 12.1
 LDTP06096  Flotillin-2 (FLOT2) 11.8
 LDTP10873  Prefoldin subunit 5 (PFDN5) 11.7
 LDTP01432  Mitochondrial import receptor subunit TOM70 (TOMM70) 11.7
 LDTP02364  Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) 11.2
 LDTP03030  Annexin A7 (ANXA7) 11.2
 LDTP04514  Heterogeneous nuclear ribonucleoprotein F (HNRNPF) 11.0
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 11.0
 LDTP01319  Eukaryotic translation initiation factor 3 subunit G (EIF3G) 10.9
 LDTP04092  Crk-like protein (CRKL) 10.8
 LDTP13097  Epidermal growth factor receptor substrate 15-like 1 (EPS15L1) 10.8
 LDTP05922  Dynactin subunit 2 (DCTN2) 10.7
 LDTP09563  Stromal membrane-associated protein 2 (SMAP2) 10.7
 LDTP02595  Polyadenylate-binding protein 1 (PABPC1) 10.6
 LDTP00759  Tumor protein D54 (TPD52L2) 10.5
 LDTP16962  Melanoma-associated antigen B1 (MAGEB1) 10.3
 LDTP03520  Phosphatidylethanolamine-binding protein 1 (PEBP1) 10.3
 LDTP05525  KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1) 10.2
 LDTP04241  Nuclear autoantigenic sperm protein (NASP) 10.1
 LDTP14105  YTH domain-containing family protein 2 (YTHDF2) 10.1
 LDTP12692  Armadillo repeat-containing protein 1 (ARMC1) 10.0
 LDTP00272  Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) 10.0
 LDTP07903  La-related protein 4 (LARP4) 9.9
 LDTP15840  Tetratricopeptide repeat protein 1 (TTC1) 9.9
 LDTP13467  RNA-binding protein Raly (RALY) 9.8
 LDTP04935  Prefoldin subunit 3 (VBP1) 9.7
 LDTP05821  Polyadenylate-binding protein 4 (PABPC4) 9.7
 LDTP13091  Ataxin-10 (ATXN10) 9.5
 LDTP09870  Signal transducing adapter molecule 1 (STAM) 9.4
 LDTP13657  Melanoma-associated antigen D2 (MAGED2) 9.1
 LDTP13813  Eukaryotic translation initiation factor 3 subunit L (EIF3L) 8.9
 LDTP04500  Heterogeneous nuclear ribonucleoprotein M (HNRNPM) 8.9
 LDTP00648  Melanoma-associated antigen B2 (MAGEB2) 8.9
 LDTP01677  Double-stranded RNA-binding protein Staufen homolog 1 (STAU1) 8.7
 LDTP04718  Eukaryotic translation initiation factor 3 subunit B (EIF3B) 8.6
 LDTP06487  Syntaxin-binding protein 2 (STXBP2) 8.5
 LDTP05233  55 kDa erythrocyte membrane protein (MPP1) 8.5
 LDTP09363  TBC1 domain family member 15 (TBC1D15) 8.5
 LDTP13309  Prefoldin subunit 2 (PFDN2) 8.4
 LDTP07888  Protein unc-13 homolog D (UNC13D) 8.2
 LDTP04028  DNA mismatch repair protein Msh2 (MSH2) 8.1
 LDTP04853  Eukaryotic translation initiation factor 3 subunit E (EIF3E) 8.1
 LDTP11058  Glutamate-rich WD repeat-containing protein 1 (GRWD1) 8.0
 LDTP04395  RNA-binding protein FXR1 (FXR1) 8.0
 LDTP15976  Large ribosomal subunit protein mL46 (MRPL46) 7.9
 LDTP01021  Perilipin-3 (PLIN3) 7.8
 LDTP12468  Diablo IAP-binding mitochondrial protein (DIABLO) 7.7
 LDTP05930  SNW domain-containing protein 1 (SNW1) 7.7
 LDTP03888  T-complex protein 1 subunit zeta (CCT6A) 7.5
 LDTP04952  Heterogeneous nuclear ribonucleoprotein K (HNRNPK) 7.4
 LDTP06515  Coiled-coil domain-containing protein 6 (CCDC6) 7.3
 LDTP08902  CDGSH iron-sulfur domain-containing protein 2 (CISD2) 7.3
 LDTP05800  Serine/arginine-rich splicing factor 9 (SRSF9) 7.2
 LDTP06450  ELAV-like protein 1 (ELAVL1) 7.1
 LDTP18309  Protein HGH1 homolog (HGH1) 7.0
 LDTP11597  182 kDa tankyrase-1-binding protein (TNKS1BP1) 7.0
 LDTP07495  Caveolae-associated protein 1 (CAVIN1) 7.0
 LDTP05689  Interleukin enhancer-binding factor 3 (ILF3) 7.0
 LDTP13701  Serine/threonine-protein phosphatase 6 regulatory subunit 1 (PPP6R1) 7.0
 LDTP10815  Spermatid perinuclear RNA-binding protein (STRBP) 6.9
 LDTP06301  Eukaryotic translation initiation factor 4H (EIF4H) 6.9
 LDTP07958  Cytoplasmic FMR1-interacting protein 1 (CYFIP1) 6.8
 LDTP02480  RNA-binding protein RO60 (RO60) 6.7
 LDTP04201  T-complex protein 1 subunit epsilon (CCT5) 6.7
 LDTP05533  Kinesin light chain 1 (KLC1) 6.7
 LDTP03065  Lamin-B1 (LMNB1) 6.6
 LDTP05421  Eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) 6.5
 LDTP11682  Polyadenylate-binding protein-interacting protein 1 (PAIP1) 6.5
 LDTP05400  Lamin-B2 (LMNB2) 6.5
 LDTP09580  Programmed cell death 6-interacting protein (PDCD6IP) 6.5
 LDTP10285  Small ribosomal subunit protein mS39 (PTCD3) 6.4
 LDTP05556  Golgin subfamily A member 3 (GOLGA3) 6.4
 LDTP01073  DnaJ homolog subfamily A member 2 (DNAJA2) 6.3
 LDTP12904  Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) 6.3
 LDTP00376  Coatomer subunit epsilon (COPE) 6.2
 LDTP03509  Endoplasmic reticulum resident protein 29 (ERP29) 6.2
 LDTP04027  Matrin-3 (MATR3) 6.2
 LDTP10062  Synapse-associated protein 1 (SYAP1) 6.0
 LDTP08018  Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) 6.0
 LDTP04367  Hsc70-interacting protein (ST13) 6.0
 LDTP02263  Signal recognition particle receptor subunit alpha (SRPRA) 6.0
 LDTP06121  Caprin-1 (CAPRIN1) 5.9
 LDTP05259  Heterogeneous nuclear ribonucleoprotein U (HNRNPU) 5.9
 LDTP06366  Poly(rC)-binding protein 1 (PCBP1) 5.8
 LDTP09721  DnaJ homolog subfamily C member 9 (DNAJC9) 5.8
 LDTP00223  26S proteasome non-ATPase regulatory subunit 11 (PSMD11) 5.8
 LDTP10847  Protein Niban 2 (NIBAN2) 5.8
 LDTP11019  Endophilin-A2 (SH3GL1) 5.7
 LDTP05697  Heat shock protein 75 kDa, mitochondrial (TRAP1) 5.6
 LDTP06543  DNA damage-binding protein 1 (DDB1) 5.6
 LDTP04117  Ras GTPase-activating-like protein IQGAP1 (IQGAP1) 5.6
 LDTP03619  Stress-induced-phosphoprotein 1 (STIP1) 5.5
 LDTP09917  Rho guanine nucleotide exchange factor 1 (ARHGEF1) 5.5
 LDTP14172  Sorting nexin-9 (SNX9) 5.5
 LDTP00843  Alpha-actinin-4 (ACTN4) 5.4
 LDTP14216  Coatomer subunit gamma-1 (COPG1) 5.4
 LDTP06391  Protein transport protein Sec23B (SEC23B) 5.4
 LDTP03982  Epidermal growth factor receptor substrate 15 (EPS15) 5.4
 LDTP11833  Rab3 GTPase-activating protein non-catalytic subunit (RAB3GAP2) 5.4
 LDTP01456  Pre-mRNA-processing factor 6 (PRPF6) 5.4
 LDTP04355  Rab GDP dissociation inhibitor beta (GDI2) 5.4
 LDTP00236  Transcription elongation factor SPT5 (SUPT5H) 5.3
 LDTP18494  Tropomodulin-3 (TMOD3) 5.3
 LDTP03397  Replication protein A 70 kDa DNA-binding subunit (RPA1) 5.3
 LDTP13519  Proteasome activator complex subunit 2 (PSME2) 5.3
 LDTP01933  Spectrin alpha chain, erythrocytic 1 (SPTA1) 5.3
 LDTP14951  Beta-actin-like protein 2 (ACTBL2) 5.2
 LDTP05113  T-complex protein 1 subunit beta (CCT2) 5.2
 LDTP00306  Pescadillo homolog (PES1) 5.2
 LDTP04917  Proteasome activator complex subunit 3 (PSME3) 5.1
 LDTP04902  Actin-related protein 3 (ACTR3) 5.1
 LDTP08387  Dynein axonemal assembly factor 5 (DNAAF5) 5.1
 LDTP02750  Heterogeneous nuclear ribonucleoprotein L (HNRNPL) 5.1
 LDTP06598  Fascin (FSCN1) 5.1
 LDTP06281  Condensin complex subunit 1 (NCAPD2) 5.0

References

1 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.