Details of the Target

General Information of Target

Target ID LDTP00756
Target Name Heterogeneous nuclear ribonucleoprotein R (HNRNPR)
Gene Name HNRNPR
Gene ID 10236
Synonyms
HNRPR; Heterogeneous nuclear ribonucleoprotein R; hnRNP R
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MANQVNGNAVQLKEEEEPMDTSSVTHTEHYKTLIEAGLPQKVAERLDEIFQTGLVAYVDL
DERAIDALREFNEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQREKQGSKVQESTK
GPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDE
LVPLFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVC
ISVANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHK
SAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKS
FSEFGKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQ
AARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGYDYH
DYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAPPPPRGRGAPPPRGRAGYSQRGAPLGPPR
GSRGGRGGPAQQQRGRGSRGSRGNRGGNVGGKRKADGYNQPDSKRRQTNNQQNWGSQPIA
QQPLQQGGDYSGNYGYNNDNQEFYQDTYGQQWK
Target Bioclass
Other
Subcellular location
Nucleus
Function
Component of ribonucleosomes, which are complexes of at least 20 other different heterogeneous nuclear ribonucleoproteins (hnRNP). hnRNP play an important role in processing of precursor mRNA in the nucleus.
Uniprot ID
O43390
Ensemble ID
ENST00000302271.11
HGNC ID
HGNC:5047

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
MEWO SNV: p.R423Ter DBIA    Probe Info 
P31FUJ SNV: p.R565H DBIA    Probe Info 
SNGM SNV: p.C240Y DBIA    Probe Info 
TOV21G SNV: p.V276I DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 48 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		10.87  LDD0402  [1]
P1
 Probe Info  		10.00  LDD0452  [2]
P2
 Probe Info  		10.00  LDD0453  [2]
P3
 Probe Info  		10.00  LDD0454  [2]
P8
 Probe Info  		10.00  LDD0455  [2]
A-EBA
 Probe Info  		3.65  LDD0215  [3]
CY-1
 Probe Info  		100.00  LDD0243  [4]
CY4
 Probe Info  		100.00  LDD0244  [4]
N1
 Probe Info  		100.00  LDD0242  [4]
TH211
 Probe Info  		Y208(20.00); Y436(20.00); Y435(17.32); Y434(13.62)  LDD0257  [5]
TH216
 Probe Info  		Y435(20.00); Y436(20.00); Y431(17.42); Y208(16.76)  LDD0259  [5]
1oxF11yne
 Probe Info  		N.A.  LDD0193  [6]
ONAyne
 Probe Info  		K300(7.69)  LDD0274  [7]
STPyne
 Probe Info  		K171(7.14); K259(10.00); K285(1.25); K286(8.33)  LDD0277  [7]
AZ-9
 Probe Info  		D139(10.00)  LDD2209  [8]
Probe 1
 Probe Info  		Y136(29.24); Y147(7.49); Y156(10.83); Y177(42.85)  LDD3495  [9]
DBIA
 Probe Info  		C214(2.85); C240(1.37); C226(2.86)  LDD3310  [10]
BTD
 Probe Info  		C226(1.08); C99(0.88); C292(1.03)  LDD2089  [11]
AHL-Pu-1
 Probe Info  		C99(2.85)  LDD0171  [12]
HHS-482
 Probe Info  		Y431(0.87); Y434(0.89); Y435(1.45); Y436(0.87)  LDD0285  [13]
HHS-475
 Probe Info  		Y435(0.54); Y436(0.62); Y431(0.75); Y578(0.80)  LDD0264  [14]
AMP probe
 Probe Info  		N.A.  LDD0200  [15]
ATP probe
 Probe Info  		K103(0.00); K300(0.00); K374(0.00); K255(0.00)  LDD0199  [15]
1d-yne
 Probe Info  		K84(0.00); K146(0.00)  LDD0358  [16]
4-Iodoacetamidophenylacetylene
 Probe Info  		C292(0.00); C214(0.00); C226(0.00); C99(0.00)  LDD0038  [17]
IA-alkyne
 Probe Info  		C226(0.00); C292(0.00); C214(0.00); C99(0.00)  LDD0032  [18]
IPIAA_H
 Probe Info  		C292(0.00); C226(0.00)  LDD0030  [19]
IPIAA_L
 Probe Info  		C292(0.00); C226(0.00); C214(0.00)  LDD0031  [19]
Lodoacetamide azide
 Probe Info  		C292(0.00); C214(0.00); C226(0.00); C99(0.00)  LDD0037  [17]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [20]
TFBX
 Probe Info  		C99(0.00); C292(0.00)  LDD0027  [20]
WYneO
 Probe Info  		N.A.  LDD0022  [21]
Compound 10
 Probe Info  		C214(0.00); C226(0.00); C292(0.00)  LDD2216  [22]
Compound 11
 Probe Info  		C214(0.00); C226(0.00); C292(0.00)  LDD2213  [22]
IPM
 Probe Info  		N.A.  LDD0005  [21]
NHS
 Probe Info  		K584(0.00); K259(0.00); K366(0.00); K574(0.00)  LDD0010  [21]
OSF
 Probe Info  		Y435(0.00); Y434(0.00); Y436(0.00); Y431(0.00)  LDD0029  [23]
PF-06672131
 Probe Info  		N.A.  LDD0017  [24]
SF
 Probe Info  		Y431(0.00); Y208(0.00); K341(0.00); Y578(0.00)  LDD0028  [23]
Ox-W18
 Probe Info  		N.A.  LDD2175  [25]
1c-yne
 Probe Info  		K300(0.00); K146(0.00); K171(0.00); K315(0.00)  LDD0228  [16]
Acrolein
 Probe Info  		H437(0.00); H280(0.00); C226(0.00); H380(0.00)  LDD0217  [26]
Crotonaldehyde
 Probe Info  		H437(0.00); H380(0.00); C226(0.00); H90(0.00)  LDD0219  [26]
Methacrolein
 Probe Info  		H437(0.00); C226(0.00)  LDD0218  [26]
W1
 Probe Info  		C99(0.00); C226(0.00); C292(0.00)  LDD0236  [27]
NAIA_5
 Probe Info  		C226(0.00); C292(0.00); C214(0.00); C240(0.00)  LDD2223  [28]
TER-AC
 Probe Info  		N.A.  LDD0426  [29]
HHS-465
 Probe Info  		Y431(0.00); Y434(0.00); Y435(0.00)  LDD2240  [30]
PAL-AfBPP Probe
Click To Hide/Show 24 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C004
 Probe Info  		6.63  LDD1714  [31]
C087
 Probe Info  		7.06  LDD1779  [31]
C129
 Probe Info  		4.99  LDD1811  [31]
C165
 Probe Info  		18.77  LDD1845  [31]
C166
 Probe Info  		7.16  LDD1846  [31]
C218
 Probe Info  		11.16  LDD1892  [31]
C232
 Probe Info  		38.59  LDD1905  [31]
C338
 Probe Info  		21.26  LDD2001  [31]
C348
 Probe Info  		10.63  LDD2009  [31]
C353
 Probe Info  		7.01  LDD2014  [31]
C420
 Probe Info  		10.56  LDD2075  [31]
FFF probe11
 Probe Info  		13.19  LDD0471  [32]
FFF probe12
 Probe Info  		6.30  LDD0473  [32]
FFF probe13
 Probe Info  		16.33  LDD0475  [32]
FFF probe14
 Probe Info  		12.07  LDD0477  [32]
FFF probe2
 Probe Info  		20.00  LDD0463  [32]
FFF probe3
 Probe Info  		14.90  LDD0464  [32]
FFF probe6
 Probe Info  		5.79  LDD0467  [32]
JN0003
 Probe Info  		13.19  LDD0469  [32]
STS-2
 Probe Info  		1.29  LDD0139  [33]
VE-P
 Probe Info  		N.A.  LDD0396  [34]
DA-2
 Probe Info  		N.A.  LDD0070  [35]
OEA-DA
 Probe Info  		4.35  LDD0046  [36]
STS-1
 Probe Info  		N.A.  LDD0068  [37]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C226(0.94)  LDD2142  [11]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C226(1.11); C240(0.70)  LDD2112  [11]
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C226(1.14)  LDD2095  [11]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C226(0.94)  LDD2117  [11]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C226(1.34)  LDD2152  [11]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C226(0.94)  LDD2103  [11]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C226(0.58); C99(0.51)  LDD2132  [11]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C226(0.39)  LDD2131  [11]
 LDCM0026  4SU-RNA+native RNA DM93 C99(2.85)  LDD0171  [12]
 LDCM0214  AC1 HEK-293T C240(1.01); C226(0.90); C99(0.94); C292(0.83)  LDD1507  [38]
 LDCM0215  AC10 HEK-293T C240(1.03); C226(0.95); C99(0.93); C292(0.87)  LDD1508  [38]
 LDCM0226  AC11 HEK-293T C240(1.03); C226(1.01); C99(1.00); C292(0.92)  LDD1509  [38]
 LDCM0237  AC12 HEK-293T C240(0.96); C226(0.96); C99(1.07); C292(0.83)  LDD1510  [38]
 LDCM0259  AC14 HEK-293T C240(1.00); C226(1.17); C99(1.02); C292(1.04)  LDD1512  [38]
 LDCM0270  AC15 HEK-293T C240(1.00); C226(1.17); C99(0.96); C292(1.00)  LDD1513  [38]
 LDCM0276  AC17 HEK-293T C240(0.99); C226(0.94); C99(0.94); C292(0.93)  LDD1515  [38]
 LDCM0277  AC18 HEK-293T C240(0.92); C226(1.07); C99(0.96); C292(0.99)  LDD1516  [38]
 LDCM0278  AC19 HEK-293T C240(0.91); C226(0.96); C99(0.83); C292(0.83)  LDD1517  [38]
 LDCM0279  AC2 HEK-293T C240(1.03); C226(1.01); C99(0.98); C292(1.00)  LDD1518  [38]
 LDCM0280  AC20 HEK-293T C240(1.05); C226(1.12); C99(1.01); C292(0.99)  LDD1519  [38]
 LDCM0281  AC21 HEK-293T C240(0.97); C226(0.98); C99(1.00); C292(1.07)  LDD1520  [38]
 LDCM0282  AC22 HEK-293T C240(0.98); C226(1.18); C99(1.00); C292(1.06)  LDD1521  [38]
 LDCM0283  AC23 HEK-293T C240(1.04); C226(1.11); C99(1.01); C292(1.03)  LDD1522  [38]
 LDCM0284  AC24 HEK-293T C240(1.02); C226(1.20); C99(1.02); C292(1.01)  LDD1523  [38]
 LDCM0285  AC25 HEK-293T C240(1.01); C226(0.71); C99(0.94); C292(0.84)  LDD1524  [38]
 LDCM0286  AC26 HEK-293T C240(0.98); C226(0.99); C99(0.95); C292(1.03)  LDD1525  [38]
 LDCM0287  AC27 HEK-293T C240(1.00); C226(1.18); C99(0.95); C292(0.96)  LDD1526  [38]
 LDCM0288  AC28 HEK-293T C240(1.01); C226(1.03); C99(1.00); C292(0.93)  LDD1527  [38]
 LDCM0289  AC29 HEK-293T C240(0.98); C226(0.93); C99(0.98); C292(1.04)  LDD1528  [38]
 LDCM0290  AC3 HEK-293T C240(1.00); C226(0.77); C99(0.96); C292(0.95)  LDD1529  [38]
 LDCM0291  AC30 HEK-293T C240(0.99); C226(1.24); C99(0.99); C292(1.09)  LDD1530  [38]
 LDCM0292  AC31 HEK-293T C240(0.98); C226(1.03); C99(1.01); C292(1.01)  LDD1531  [38]
 LDCM0293  AC32 HEK-293T C240(1.03); C226(1.05); C99(1.03); C292(0.93)  LDD1532  [38]
 LDCM0294  AC33 HEK-293T C240(0.99); C226(0.75); C99(0.98); C292(0.83)  LDD1533  [38]
 LDCM0295  AC34 HEK-293T C240(0.96); C226(0.98); C99(0.98); C292(0.96)  LDD1534  [38]
 LDCM0296  AC35 HEK-293T C240(0.99); C226(0.98); C99(0.97); C292(0.96)  LDD1535  [38]
 LDCM0297  AC36 HEK-293T C240(0.99); C226(1.02); C99(1.06); C292(0.85)  LDD1536  [38]
 LDCM0298  AC37 HEK-293T C240(1.05); C226(1.01); C99(1.11); C292(1.03)  LDD1537  [38]
 LDCM0299  AC38 HEK-293T C240(1.01); C226(1.08); C99(1.07); C292(1.03)  LDD1538  [38]
 LDCM0300  AC39 HEK-293T C240(0.99); C226(1.13); C99(1.01); C292(0.94)  LDD1539  [38]
 LDCM0301  AC4 HEK-293T C240(0.99); C226(1.02); C99(1.05); C292(0.98)  LDD1540  [38]
 LDCM0302  AC40 HEK-293T C240(1.00); C226(1.14); C99(1.14); C292(0.94)  LDD1541  [38]
 LDCM0303  AC41 HEK-293T C240(0.94); C226(0.76); C99(0.96); C292(0.81)  LDD1542  [38]
 LDCM0304  AC42 HEK-293T C240(0.96); C226(0.98); C99(0.95); C292(0.92)  LDD1543  [38]
 LDCM0305  AC43 HEK-293T C240(1.01); C226(0.94); C99(0.96); C292(1.00)  LDD1544  [38]
 LDCM0306  AC44 HEK-293T C240(0.99); C226(0.96); C99(1.09); C292(0.80)  LDD1545  [38]
 LDCM0307  AC45 HEK-293T C240(1.04); C226(0.95); C99(1.06); C292(0.97)  LDD1546  [38]
 LDCM0308  AC46 HEK-293T C240(1.00); C226(1.21); C99(1.01); C292(1.00)  LDD1547  [38]
 LDCM0309  AC47 HEK-293T C240(0.97); C226(1.00); C99(0.99); C292(1.01)  LDD1548  [38]
 LDCM0310  AC48 HEK-293T C240(1.05); C226(1.11); C99(1.08); C292(0.89)  LDD1549  [38]
 LDCM0311  AC49 HEK-293T C240(1.02); C226(0.63); C99(0.96); C292(0.83)  LDD1550  [38]
 LDCM0312  AC5 HEK-293T C240(1.04); C226(0.93); C99(1.05); C292(1.07)  LDD1551  [38]
 LDCM0313  AC50 HEK-293T C240(1.03); C226(1.02); C99(0.97); C292(0.97)  LDD1552  [38]
 LDCM0314  AC51 HEK-293T C240(1.04); C226(0.98); C99(1.03); C292(1.02)  LDD1553  [38]
 LDCM0315  AC52 HEK-293T C240(1.01); C226(0.98); C99(1.07); C292(0.84)  LDD1554  [38]
 LDCM0316  AC53 HEK-293T C240(1.01); C226(0.91); C99(1.06); C292(1.02)  LDD1555  [38]
 LDCM0317  AC54 HEK-293T C240(1.00); C226(1.09); C99(1.02); C292(1.02)  LDD1556  [38]
 LDCM0318  AC55 HEK-293T C240(0.97); C226(1.11); C99(0.96); C292(0.97)  LDD1557  [38]
 LDCM0319  AC56 HEK-293T C240(1.02); C226(1.13); C99(1.10); C292(0.91)  LDD1558  [38]
 LDCM0320  AC57 HEK-293T C240(0.90); C226(0.66); C99(0.91); C292(0.80)  LDD1559  [38]
 LDCM0321  AC58 HEK-293T C240(0.95); C226(1.08); C99(0.98); C292(1.00)  LDD1560  [38]
 LDCM0322  AC59 HEK-293T C240(1.07); C226(0.89); C99(0.98); C292(1.07)  LDD1561  [38]
 LDCM0323  AC6 HEK-293T C240(0.93); C226(0.98); C99(0.99); C292(1.03)  LDD1562  [38]
 LDCM0324  AC60 HEK-293T C240(1.01); C226(0.99); C99(1.03); C292(0.87)  LDD1563  [38]
 LDCM0325  AC61 HEK-293T C240(0.93); C226(0.99); C99(1.00); C292(0.99)  LDD1564  [38]
 LDCM0326  AC62 HEK-293T C240(0.94); C226(1.06); C99(0.99); C292(0.97)  LDD1565  [38]
 LDCM0327  AC63 HEK-293T C240(0.99); C226(1.08); C99(0.99); C292(0.95)  LDD1566  [38]
 LDCM0328  AC64 HEK-293T C240(0.98); C226(1.01); C99(1.07); C292(1.02)  LDD1567  [38]
 LDCM0334  AC7 HEK-293T C240(1.01); C226(1.02); C99(1.03); C292(1.02)  LDD1568  [38]
 LDCM0345  AC8 HEK-293T C240(1.00); C226(1.05); C99(1.05); C292(1.03)  LDD1569  [38]
 LDCM0545  Acetamide MDA-MB-231 C226(0.79); C99(0.56)  LDD2138  [11]
 LDCM0520  AKOS000195272 MDA-MB-231 C226(0.70)  LDD2113  [11]
 LDCM0248  AKOS034007472 HEK-293T C240(1.00); C226(0.92); C99(1.06); C292(1.11)  LDD1511  [38]
 LDCM0356  AKOS034007680 HEK-293T C240(0.96); C226(0.76); C99(0.95); C292(0.79)  LDD1570  [38]
 LDCM0275  AKOS034007705 HEK-293T C240(1.04); C226(1.26); C99(1.06); C292(1.03)  LDD1514  [38]
 LDCM0498  BS-3668 MDA-MB-231 C226(1.06); C99(0.62)  LDD2091  [11]
 LDCM0108  Chloroacetamide HeLa H280(0.00); H437(0.00); C226(0.00); C214(0.00)  LDD0222  [26]
 LDCM0632  CL-Sc Hep-G2 C240(0.85)  LDD2227  [28]
 LDCM0367  CL1 HEK-293T C240(0.93); C226(0.96); C99(0.98); C292(0.93)  LDD1571  [38]
 LDCM0368  CL10 HEK-293T C240(0.90); C226(1.17); C99(0.84); C292(0.76)  LDD1572  [38]
 LDCM0369  CL100 HEK-293T C240(0.98); C226(0.98); C99(0.96); C292(0.92)  LDD1573  [38]
 LDCM0370  CL101 HEK-293T C240(0.97); C226(0.95); C99(0.98); C292(0.95)  LDD1574  [38]
 LDCM0371  CL102 HEK-293T C240(0.93); C226(0.86); C99(0.97); C292(0.81)  LDD1575  [38]
 LDCM0372  CL103 HEK-293T C240(1.04); C226(1.02); C99(1.01); C292(0.88)  LDD1576  [38]
 LDCM0373  CL104 HEK-293T C240(0.99); C226(0.91); C99(0.99); C292(0.95)  LDD1577  [38]
 LDCM0374  CL105 HEK-293T C240(0.97); C226(0.94); C99(0.98); C292(0.99)  LDD1578  [38]
 LDCM0375  CL106 HEK-293T C240(0.98); C226(1.00); C99(0.97); C292(0.91)  LDD1579  [38]
 LDCM0376  CL107 HEK-293T C240(1.02); C226(1.18); C99(1.05); C292(0.98)  LDD1580  [38]
 LDCM0377  CL108 HEK-293T C240(1.04); C226(1.11); C99(0.95); C292(1.00)  LDD1581  [38]
 LDCM0378  CL109 HEK-293T C240(0.94); C226(0.98); C99(0.96); C292(0.98)  LDD1582  [38]
 LDCM0379  CL11 HEK-293T C240(0.92); C226(1.55); C99(0.97); C292(0.99)  LDD1583  [38]
 LDCM0380  CL110 HEK-293T C240(0.94); C226(0.88); C99(0.87); C292(0.80)  LDD1584  [38]
 LDCM0381  CL111 HEK-293T C240(1.01); C226(0.86); C99(0.99); C292(0.86)  LDD1585  [38]
 LDCM0382  CL112 HEK-293T C240(0.99); C226(1.05); C99(1.01); C292(0.95)  LDD1586  [38]
 LDCM0383  CL113 HEK-293T C240(1.04); C226(0.93); C99(1.02); C292(0.92)  LDD1587  [38]
 LDCM0384  CL114 HEK-293T C240(0.99); C226(0.89); C99(0.97); C292(0.82)  LDD1588  [38]
 LDCM0385  CL115 HEK-293T C240(1.02); C226(1.11); C99(1.01); C292(0.90)  LDD1589  [38]
 LDCM0386  CL116 HEK-293T C240(1.01); C226(1.04); C99(0.97); C292(0.93)  LDD1590  [38]
 LDCM0387  CL117 HEK-293T C240(0.96); C226(0.93); C99(0.98); C292(0.89)  LDD1591  [38]
 LDCM0388  CL118 HEK-293T C240(1.05); C226(0.99); C99(1.05); C292(0.95)  LDD1592  [38]
 LDCM0389  CL119 HEK-293T C240(1.04); C226(1.09); C99(1.06); C292(0.88)  LDD1593  [38]
 LDCM0390  CL12 HEK-293T C240(0.91); C226(1.84); C99(1.13); C292(0.94)  LDD1594  [38]
 LDCM0391  CL120 HEK-293T C240(1.01); C226(0.94); C99(0.98); C292(0.94)  LDD1595  [38]
 LDCM0392  CL121 HEK-293T C240(1.00); C226(0.94); C99(0.98); C292(1.02)  LDD1596  [38]
 LDCM0393  CL122 HEK-293T C240(0.99); C226(0.97); C99(1.02); C292(0.89)  LDD1597  [38]
 LDCM0394  CL123 HEK-293T C240(0.95); C226(0.92); C99(0.92); C292(0.90)  LDD1598  [38]
 LDCM0395  CL124 HEK-293T C240(1.00); C226(0.99); C99(0.97); C292(0.92)  LDD1599  [38]
 LDCM0396  CL125 HEK-293T C240(1.01); C226(1.01); C99(0.96); C292(1.10)  LDD1600  [38]
 LDCM0397  CL126 HEK-293T C240(0.97); C226(0.97); C99(1.00); C292(0.90)  LDD1601  [38]
 LDCM0398  CL127 HEK-293T C240(0.94); C226(0.93); C99(0.99); C292(0.93)  LDD1602  [38]
 LDCM0399  CL128 HEK-293T C240(0.93); C226(0.91); C99(0.97); C292(0.98)  LDD1603  [38]
 LDCM0400  CL13 HEK-293T C240(1.04); C226(0.79); C99(0.98); C292(0.99)  LDD1604  [38]
 LDCM0401  CL14 HEK-293T C240(1.07); C226(0.94); C99(1.09); C292(0.85)  LDD1605  [38]
 LDCM0402  CL15 HEK-293T C240(0.96); C226(0.78); C99(0.95); C292(0.71)  LDD1606  [38]
 LDCM0403  CL16 HEK-293T C240(1.03); C226(0.99); C99(0.98); C292(0.88)  LDD1607  [38]
 LDCM0404  CL17 HEK-293T C240(0.91); C226(0.50); C99(0.86); C292(0.63)  LDD1608  [38]
 LDCM0405  CL18 HEK-293T C240(1.02); C226(0.94); C99(1.02); C292(0.99)  LDD1609  [38]
 LDCM0406  CL19 HEK-293T C240(1.17); C226(1.21); C99(1.02); C292(0.95)  LDD1610  [38]
 LDCM0407  CL2 HEK-293T C240(1.03); C226(0.78); C99(1.08); C292(0.91)  LDD1611  [38]
 LDCM0408  CL20 HEK-293T C240(0.95); C226(0.91); C99(1.14); C292(0.84)  LDD1612  [38]
 LDCM0409  CL21 HEK-293T C240(0.88); C226(1.02); C99(1.08); C292(0.95)  LDD1613  [38]
 LDCM0410  CL22 HEK-293T C240(0.99); C226(1.42); C99(1.07); C292(0.98)  LDD1614  [38]
 LDCM0411  CL23 HEK-293T C240(1.04); C226(1.81); C99(1.02); C292(1.03)  LDD1615  [38]
 LDCM0412  CL24 HEK-293T C240(1.00); C226(1.63); C99(1.19); C292(0.95)  LDD1616  [38]
 LDCM0413  CL25 HEK-293T C240(0.89); C226(0.85); C99(0.98); C292(0.93)  LDD1617  [38]
 LDCM0414  CL26 HEK-293T C240(1.01); C226(0.92); C99(1.04); C292(0.90)  LDD1618  [38]
 LDCM0415  CL27 HEK-293T C240(0.95); C226(1.01); C99(1.04); C292(0.92)  LDD1619  [38]
 LDCM0416  CL28 HEK-293T C240(1.06); C226(1.00); C99(0.98); C292(0.90)  LDD1620  [38]
 LDCM0417  CL29 HEK-293T C240(0.95); C226(0.76); C99(1.01); C292(0.91)  LDD1621  [38]
 LDCM0418  CL3 HEK-293T C240(1.03); C226(0.94); C99(1.06); C292(0.81)  LDD1622  [38]
 LDCM0419  CL30 HEK-293T C240(0.96); C226(0.98); C99(1.03); C292(1.04)  LDD1623  [38]
 LDCM0420  CL31 HEK-293T C240(1.00); C226(1.15); C99(0.97); C292(0.92)  LDD1624  [38]
 LDCM0421  CL32 HEK-293T C240(0.99); C226(1.00); C99(1.04); C292(0.91)  LDD1625  [38]
 LDCM0422  CL33 HEK-293T C240(0.71); C226(0.96); C99(0.91); C292(0.96)  LDD1626  [38]
 LDCM0423  CL34 HEK-293T C240(0.80); C226(1.55); C99(1.04); C292(1.04)  LDD1627  [38]
 LDCM0424  CL35 HEK-293T C240(0.93); C226(2.25); C99(1.01); C292(1.05)  LDD1628  [38]
 LDCM0425  CL36 HEK-293T C240(0.90); C226(2.08); C99(1.08); C292(1.10)  LDD1629  [38]
 LDCM0426  CL37 HEK-293T C240(0.95); C226(0.97); C99(0.99); C292(1.01)  LDD1630  [38]
 LDCM0428  CL39 HEK-293T C240(1.10); C226(1.14); C99(1.02); C292(0.94)  LDD1632  [38]
 LDCM0429  CL4 HEK-293T C240(0.93); C226(0.83); C99(0.97); C292(0.77)  LDD1633  [38]
 LDCM0430  CL40 HEK-293T C240(1.07); C226(1.00); C99(0.99); C292(1.03)  LDD1634  [38]
 LDCM0431  CL41 HEK-293T C240(0.97); C226(0.71); C99(0.96); C292(0.88)  LDD1635  [38]
 LDCM0432  CL42 HEK-293T C240(0.91); C226(1.08); C99(1.03); C292(1.14)  LDD1636  [38]
 LDCM0433  CL43 HEK-293T C240(1.02); C226(1.43); C99(1.00); C292(1.10)  LDD1637  [38]
 LDCM0434  CL44 HEK-293T C240(0.95); C226(1.05); C99(1.01); C292(0.94)  LDD1638  [38]
 LDCM0435  CL45 HEK-293T C240(0.87); C226(0.99); C99(0.97); C292(1.01)  LDD1639  [38]
 LDCM0436  CL46 HEK-293T C240(0.93); C226(1.89); C99(1.01); C292(1.05)  LDD1640  [38]
 LDCM0437  CL47 HEK-293T C240(0.96); C226(2.10); C99(1.01); C292(1.07)  LDD1641  [38]
 LDCM0438  CL48 HEK-293T C240(0.88); C226(2.07); C99(1.08); C292(1.04)  LDD1642  [38]
 LDCM0439  CL49 HEK-293T C240(0.92); C226(0.99); C99(1.01); C292(1.02)  LDD1643  [38]
 LDCM0440  CL5 HEK-293T C240(0.90); C226(0.51); C99(0.98); C292(0.78)  LDD1644  [38]
 LDCM0441  CL50 HEK-293T C240(1.00); C226(0.85); C99(1.07); C292(0.80)  LDD1645  [38]
 LDCM0443  CL52 HEK-293T C240(1.03); C226(0.98); C99(0.99); C292(0.88)  LDD1646  [38]
 LDCM0444  CL53 HEK-293T C240(0.87); C226(0.58); C99(0.91); C292(0.71)  LDD1647  [38]
 LDCM0445  CL54 HEK-293T C240(0.90); C226(0.85); C99(0.91); C292(0.93)  LDD1648  [38]
 LDCM0446  CL55 HEK-293T C240(1.05); C226(1.37); C99(0.98); C292(1.02)  LDD1649  [38]
 LDCM0447  CL56 HEK-293T C240(0.95); C226(1.07); C99(1.10); C292(0.89)  LDD1650  [38]
 LDCM0448  CL57 HEK-293T C240(0.80); C226(0.98); C99(1.00); C292(1.01)  LDD1651  [38]
 LDCM0449  CL58 HEK-293T C240(0.83); C226(1.31); C99(1.07); C292(0.99)  LDD1652  [38]
 LDCM0450  CL59 HEK-293T C240(0.93); C226(1.99); C99(1.01); C292(1.08)  LDD1653  [38]
 LDCM0451  CL6 HEK-293T C240(0.82); C226(0.75); C99(0.91); C292(0.86)  LDD1654  [38]
 LDCM0452  CL60 HEK-293T C240(0.92); C226(1.99); C99(1.12); C292(1.00)  LDD1655  [38]
 LDCM0453  CL61 HEK-293T C240(0.99); C226(0.92); C99(1.03); C292(0.96)  LDD1656  [38]
 LDCM0454  CL62 HEK-293T C240(1.03); C226(0.94); C99(1.07); C292(0.91)  LDD1657  [38]
 LDCM0455  CL63 HEK-293T C240(1.00); C226(1.07); C99(1.06); C292(0.94)  LDD1658  [38]
 LDCM0456  CL64 HEK-293T C240(0.92); C226(0.93); C99(0.96); C292(0.88)  LDD1659  [38]
 LDCM0457  CL65 HEK-293T C240(0.90); C226(0.55); C99(0.97); C292(0.82)  LDD1660  [38]
 LDCM0458  CL66 HEK-293T C240(0.90); C226(0.90); C99(0.97); C292(0.94)  LDD1661  [38]
 LDCM0459  CL67 HEK-293T C240(0.98); C226(1.27); C99(1.03); C292(1.03)  LDD1662  [38]
 LDCM0460  CL68 HEK-293T C240(0.86); C226(1.01); C99(1.07); C292(0.86)  LDD1663  [38]
 LDCM0461  CL69 HEK-293T C240(0.84); C226(1.10); C99(1.05); C292(1.00)  LDD1664  [38]
 LDCM0462  CL7 HEK-293T C240(0.99); C226(0.98); C99(0.97); C292(0.91)  LDD1665  [38]
 LDCM0463  CL70 HEK-293T C240(0.85); C226(1.45); C99(1.04); C292(0.99)  LDD1666  [38]
 LDCM0464  CL71 HEK-293T C240(0.93); C226(2.07); C99(1.03); C292(1.12)  LDD1667  [38]
 LDCM0465  CL72 HEK-293T C240(0.94); C226(1.97); C99(1.09); C292(0.98)  LDD1668  [38]
 LDCM0466  CL73 HEK-293T C240(0.94); C226(1.00); C99(0.99); C292(1.09)  LDD1669  [38]
 LDCM0467  CL74 HEK-293T C240(1.07); C226(1.06); C99(1.04); C292(1.00)  LDD1670  [38]
 LDCM0469  CL76 HEK-293T C240(0.97); C226(0.96); C99(1.02); C292(0.95)  LDD1672  [38]
 LDCM0470  CL77 HEK-293T C240(0.83); C226(0.69); C99(0.93); C292(0.76)  LDD1673  [38]
 LDCM0471  CL78 HEK-293T C240(0.92); C226(1.00); C99(1.00); C292(1.02)  LDD1674  [38]
 LDCM0472  CL79 HEK-293T C240(1.07); C226(1.14); C99(1.02); C292(1.12)  LDD1675  [38]
 LDCM0473  CL8 HEK-293T C240(0.60); C226(0.86); C99(0.94); C292(0.71)  LDD1676  [38]
 LDCM0474  CL80 HEK-293T C240(0.98); C226(1.18); C99(1.13); C292(1.01)  LDD1677  [38]
 LDCM0475  CL81 HEK-293T C240(0.88); C226(1.04); C99(1.06); C292(1.06)  LDD1678  [38]
 LDCM0476  CL82 HEK-293T C240(0.85); C226(1.37); C99(1.03); C292(1.13)  LDD1679  [38]
 LDCM0477  CL83 HEK-293T C240(0.88); C226(1.90); C99(0.98); C292(1.13)  LDD1680  [38]
 LDCM0478  CL84 HEK-293T C240(0.83); C226(1.72); C99(1.09); C292(1.05)  LDD1681  [38]
 LDCM0479  CL85 HEK-293T C240(1.04); C226(0.92); C99(0.99); C292(1.04)  LDD1682  [38]
 LDCM0480  CL86 HEK-293T C240(0.98); C226(0.99); C99(1.03); C292(0.90)  LDD1683  [38]
 LDCM0481  CL87 HEK-293T C240(0.96); C226(0.88); C99(1.04); C292(0.85)  LDD1684  [38]
 LDCM0482  CL88 HEK-293T C240(0.93); C226(0.95); C99(1.00); C292(0.99)  LDD1685  [38]
 LDCM0483  CL89 HEK-293T C240(0.88); C226(0.74); C99(0.98); C292(0.81)  LDD1686  [38]
 LDCM0484  CL9 HEK-293T C240(0.92); C226(0.94); C99(1.07); C292(0.93)  LDD1687  [38]
 LDCM0485  CL90 HEK-293T C240(0.67); C226(0.75); C99(0.78); C292(0.73)  LDD1688  [38]
 LDCM0486  CL91 HEK-293T C240(1.00); C226(0.97); C99(1.04); C292(1.01)  LDD1689  [38]
 LDCM0487  CL92 HEK-293T C240(0.84); C226(0.93); C99(1.05); C292(0.81)  LDD1690  [38]
 LDCM0488  CL93 HEK-293T C240(0.84); C226(0.98); C99(1.00); C292(1.03)  LDD1691  [38]
 LDCM0489  CL94 HEK-293T C240(0.90); C226(1.26); C99(1.01); C292(0.99)  LDD1692  [38]
 LDCM0490  CL95 HEK-293T C240(0.74); C226(1.28); C99(1.06); C292(0.82)  LDD1693  [38]
 LDCM0491  CL96 HEK-293T C240(0.88); C226(1.40); C99(1.05); C292(0.97)  LDD1694  [38]
 LDCM0492  CL97 HEK-293T C240(0.98); C226(0.91); C99(0.97); C292(1.11)  LDD1695  [38]
 LDCM0493  CL98 HEK-293T C240(0.99); C226(0.87); C99(0.95); C292(0.91)  LDD1696  [38]
 LDCM0494  CL99 HEK-293T C240(1.02); C226(0.95); C99(0.99); C292(0.93)  LDD1697  [38]
 LDCM0495  E2913 HEK-293T C240(1.01); C226(0.93); C99(1.03); C292(0.86)  LDD1698  [38]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C240(1.26); C99(0.93); C226(0.73)  LDD1702  [11]
 LDCM0625  F8 Ramos C99(1.05); C292(0.81); C214(0.54)  LDD2187  [39]
 LDCM0572  Fragment10 MDA-MB-231 C99(2.35)  LDD1389  [40]
 LDCM0573  Fragment11 MDA-MB-231 C99(1.00)  LDD1391  [40]
 LDCM0574  Fragment12 MDA-MB-231 C99(1.02)  LDD1393  [40]
 LDCM0575  Fragment13 MDA-MB-231 C99(1.20)  LDD1395  [40]
 LDCM0576  Fragment14 MDA-MB-231 C99(0.95)  LDD1397  [40]
 LDCM0577  Fragment15 Ramos C99(1.04)  LDD1400  [40]
 LDCM0579  Fragment20 MDA-MB-231 C99(1.33)  LDD1402  [40]
 LDCM0580  Fragment21 MDA-MB-231 C99(0.79)  LDD1404  [40]
 LDCM0582  Fragment23 MDA-MB-231 C99(1.11)  LDD1408  [40]
 LDCM0583  Fragment24 Ramos C99(1.13)  LDD1410  [40]
 LDCM0584  Fragment25 MDA-MB-231 C99(0.87)  LDD1411  [40]
 LDCM0578  Fragment27 MDA-MB-231 C99(0.92)  LDD1401  [40]
 LDCM0586  Fragment28 MDA-MB-231 C99(0.79)  LDD1415  [40]
 LDCM0587  Fragment29 MDA-MB-231 C99(1.30)  LDD1417  [40]
 LDCM0588  Fragment30 MDA-MB-231 C99(0.73)  LDD1419  [40]
 LDCM0589  Fragment31 MDA-MB-231 C99(1.04)  LDD1421  [40]
 LDCM0590  Fragment32 MDA-MB-231 C99(0.88)  LDD1423  [40]
 LDCM0468  Fragment33 HEK-293T C240(0.93); C226(1.01); C99(1.01); C292(0.96)  LDD1671  [38]
 LDCM0593  Fragment35 Ramos C99(1.17)  LDD1430  [40]
 LDCM0595  Fragment37 Ramos C99(0.81)  LDD1432  [40]
 LDCM0596  Fragment38 MDA-MB-231 C99(1.20)  LDD1433  [40]
 LDCM0597  Fragment39 MDA-MB-231 C99(1.08)  LDD1435  [40]
 LDCM0566  Fragment4 MDA-MB-231 C99(1.13)  LDD1378  [40]
 LDCM0598  Fragment40 MDA-MB-231 C99(0.90)  LDD1436  [40]
 LDCM0599  Fragment41 Ramos C99(1.72)  LDD1439  [40]
 LDCM0600  Fragment42 Ramos C99(0.91)  LDD1440  [40]
 LDCM0601  Fragment43 MDA-MB-231 C99(0.90)  LDD1441  [40]
 LDCM0603  Fragment45 MDA-MB-231 C99(5.76)  LDD1444  [40]
 LDCM0604  Fragment46 MDA-MB-231 C99(1.07)  LDD1445  [40]
 LDCM0605  Fragment47 MDA-MB-231 C99(1.14)  LDD1446  [40]
 LDCM0606  Fragment48 MDA-MB-231 C99(1.19)  LDD1447  [40]
 LDCM0607  Fragment49 MDA-MB-231 C99(3.25)  LDD1448  [40]
 LDCM0608  Fragment50 MDA-MB-231 C99(1.07)  LDD1449  [40]
 LDCM0427  Fragment51 Ramos C99(0.87)  LDD1451  [40]
 LDCM0610  Fragment52 MDA-MB-231 C99(1.00)  LDD1452  [40]
 LDCM0611  Fragment53 Ramos C99(0.78)  LDD1455  [40]
 LDCM0614  Fragment56 MDA-MB-231 C99(0.82)  LDD1458  [40]
 LDCM0568  Fragment6 MDA-MB-231 C99(1.46)  LDD1382  [40]
 LDCM0569  Fragment7 MDA-MB-231 C99(0.72)  LDD1383  [40]
 LDCM0570  Fragment8 MDA-MB-231 C99(1.06)  LDD1385  [40]
 LDCM0571  Fragment9 MDA-MB-231 C99(1.11)  LDD1387  [40]
 LDCM0116  HHS-0101 DM93 Y435(0.54); Y436(0.62); Y431(0.75); Y578(0.80)  LDD0264  [14]
 LDCM0117  HHS-0201 DM93 Y435(0.58); Y436(0.80); Y431(1.30); Y434(1.53)  LDD0265  [14]
 LDCM0118  HHS-0301 DM93 Y436(0.38); Y435(0.44); Y434(0.58); Y431(0.59)  LDD0266  [14]
 LDCM0119  HHS-0401 DM93 Y436(0.67); Y434(0.78); Y431(1.01); Y435(1.84)  LDD0267  [14]
 LDCM0120  HHS-0701 DM93 Y436(0.74); Y434(1.08); Y431(1.39); Y435(1.45)  LDD0268  [14]
 LDCM0107  IAA HeLa H437(0.00); H280(0.00); H380(0.00); H90(0.00)  LDD0221  [26]
 LDCM0123  JWB131 DM93 Y431(0.87); Y434(0.89); Y435(1.45); Y436(0.87)  LDD0285  [13]
 LDCM0124  JWB142 DM93 Y431(0.65); Y434(0.63); Y435(0.46); Y436(0.62)  LDD0286  [13]
 LDCM0125  JWB146 DM93 Y431(1.23); Y434(1.52); Y435(1.39); Y436(1.42)  LDD0287  [13]
 LDCM0126  JWB150 DM93 Y431(2.93); Y434(3.12); Y435(4.82); Y436(5.79)  LDD0288  [13]
 LDCM0127  JWB152 DM93 Y431(1.75); Y434(1.74); Y435(2.14); Y436(1.48)  LDD0289  [13]
 LDCM0128  JWB198 DM93 Y431(0.67); Y434(1.01); Y435(1.00); Y436(0.99)  LDD0290  [13]
 LDCM0129  JWB202 DM93 Y431(0.30); Y434(0.31); Y435(0.33); Y436(0.31)  LDD0291  [13]
 LDCM0130  JWB211 DM93 Y431(0.78); Y434(0.91); Y435(0.61); Y436(0.84)  LDD0292  [13]
 LDCM0022  KB02 MDA-MB-231 C99(1.83)  LDD1374  [40]
 LDCM0023  KB03 MDA-MB-231 C99(1.13)  LDD1376  [40]
 LDCM0024  KB05 COLO792 C214(2.85); C240(1.37); C226(2.86)  LDD3310  [10]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C226(1.04)  LDD2102  [11]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C226(1.10)  LDD2121  [11]
 LDCM0109  NEM HeLa H280(0.00); H437(0.00); H380(0.00); H90(0.00)  LDD0223  [26]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C226(1.08); C99(0.88); C292(1.03)  LDD2089  [11]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C226(0.99)  LDD2092  [11]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C226(1.17)  LDD2093  [11]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C226(1.18)  LDD2094  [11]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C99(0.49)  LDD2096  [11]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C226(1.02)  LDD2097  [11]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C226(1.03)  LDD2098  [11]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C226(1.12)  LDD2099  [11]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C226(0.68)  LDD2100  [11]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C226(0.90); C292(0.59)  LDD2104  [11]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C226(0.71)  LDD2106  [11]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C226(0.90)  LDD2107  [11]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C226(1.20)  LDD2108  [11]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C226(0.59)  LDD2109  [11]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C226(0.85)  LDD2110  [11]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C226(1.05)  LDD2111  [11]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C226(0.85); C292(0.56)  LDD2114  [11]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C226(0.35); C99(1.45)  LDD2116  [11]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C226(2.02); C99(0.77)  LDD2118  [11]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C226(1.61); C99(1.72)  LDD2119  [11]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C226(1.01); C99(0.86)  LDD2120  [11]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C226(1.59)  LDD2122  [11]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C226(0.98)  LDD2123  [11]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C226(1.86); C99(0.57)  LDD2124  [11]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C226(0.81)  LDD2125  [11]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C226(0.60); C99(0.63)  LDD2126  [11]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C226(1.05)  LDD2127  [11]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C226(1.04)  LDD2128  [11]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C226(1.36)  LDD2129  [11]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C226(0.65)  LDD2133  [11]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C226(0.62); C99(0.35)  LDD2134  [11]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C226(1.67)  LDD2135  [11]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C226(1.19)  LDD2136  [11]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C226(0.95)  LDD2137  [11]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C226(0.76)  LDD2140  [11]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C226(0.95)  LDD2141  [11]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C226(1.06); C99(0.95)  LDD2143  [11]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C226(2.19)  LDD2144  [11]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C226(1.03)  LDD2146  [11]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C226(2.63)  LDD2147  [11]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C226(0.44); C99(0.44)  LDD2148  [11]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C226(1.28); C99(0.67)  LDD2149  [11]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C226(0.82)  LDD2150  [11]
 LDCM0131  RA190 MM1.R C214(1.49); C226(1.41)  LDD0304  [41]
 LDCM0110  W12 Hep-G2 C99(15.61)  LDD0237  [27]
 LDCM0113  W17 Hep-G2 C99(4.86)  LDD0240  [27]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein arginine N-methyltransferase 1 (PRMT1) Protein arginine N-methyltransferase family Q99873
Dexamethasone-induced Ras-related protein 1 (RASD1) RasD family Q9Y272
Other
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
KH domain-containing, RNA-binding, signal transduction-associated protein 2 (KHDRBS2) KHDRBS family Q5VWX1
Protocadherin beta-14 (PCDHB14) . Q9Y5E9
SH2/SH3 adapter protein NCK1 (NCK1) . P16333
TAR DNA-binding protein 43 (TARDBP) . Q13148

References

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3 2-Ethynylbenzaldehyde-Based, Lysine-Targeting Irreversible Covalent Inhibitors for Protein Kinases and Nonkinases. J Am Chem Soc. 2023 Feb 12. doi: 10.1021/jacs.2c11595. Online ahead of print.
Mass spectrometry data entry: PXD037665
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Mass spectrometry data entry: PXD028270
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Mass spectrometry data entry: PXD047840
11 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD044625
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Mass spectrometry data entry: PXD028853
18 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
19 SP3-Enabled Rapid and High Coverage Chemoproteomic Identification of Cell-State-Dependent Redox-Sensitive Cysteines. Mol Cell Proteomics. 2022 Apr;21(4):100218. doi: 10.1016/j.mcpro.2022.100218. Epub 2022 Feb 25.
Mass spectrometry data entry: PXD029500 , PXD031647
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Mass spectrometry data entry: PXD029255
21 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD022279
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Mass spectrometry data entry: PXD039931
24 Site-Specific Activity-Based Protein Profiling Using Phosphonate Handles. Mol Cell Proteomics. 2023 Jan;22(1):100455. doi: 10.1016/j.mcpro.2022.100455. Epub 2022 Nov 24.
Mass spectrometry data entry: PXD036569
25 Oxidative cyclization reagents reveal tryptophan cation- interactions. Nature. 2024 Mar;627(8004):680-687. doi: 10.1038/s41586-024-07140-6. Epub 2024 Mar 6.
Mass spectrometry data entry: PXD001377 , PXD005252
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD038010
31 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD007570
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Mass spectrometry data entry: PXD044402
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Mass spectrometry data entry: PXD027578
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