Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0599
Competitor Name
Fragment41
Synonyms
MLS000710558; CHEMBL1582719; SCHEMBL22196883; HMS2657P09; STK701544; AKOS000525896; SMR000280325; SR-01000312104; SR-01000312104-1; (2E)-2-cyano-3-(4-methylphenyl)-N-[2-(4-morpholinyl)ethyl]-2-propenamide; (2E)-2-cyano-3-(4-methylphenyl)-N-[2-(morpholin-4-yl)ethyl]prop-2-enamide
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 299.37
Lipid-water partition coefficient (xlogp) 1.6
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C17H21N3O2
IUPAC Name
(E)-2-cyano-3-(4-methylphenyl)-N-(2-morpholin-4-ylethyl)prop-2-enamide
Canonical SMILES
CC1=CC=C(C=C1)C=C(C#N)C(=O)NCCN2CCOCC2
InChI
InChI=1S/C17H21N3O2/c1-14-2-4-15(5-3-14)12-16(13-18)17(21)19-6-7-20-8-10-22-11-9-20/h2-5,12H,6-11H2,1H3,(H,19,21)/b16-12+
InChIKey
XWXMENKOCWBTAF-FOWTUZBSSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
IA-alkyne
 Probe Info  		100 uM Human breast adenocarcinoma cell lysate (MDA-MB-231) [1]

Target(s) List of this Competitor

145 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 1.16; 1.35  LDD1438 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 1.53  LDD1438 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 1.85  LDD1438 
3-ketoacyl-CoA thiolase, mitochondrial (ACAA2) LDTP03998 0.86  LDD1438 
3-ketoacyl-CoA thiolase, peroxisomal (ACAA1) LDTP02329 0.88  LDD1481 
4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) LDTP04232 0.75  LDD1481 
5'-nucleotidase domain-containing protein 1 (NT5DC1) LDTP17247 1.19  LDD1438 
5'-nucleotidase domain-containing protein 3 (NT5DC3) LDTP15290 1.69  LDD1481 
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (PFKFB2) LDTP01055 0.66  LDD1481 
6-phosphogluconolactonase (PGLS) LDTP14535 1.12  LDD1438 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 5.05  LDD1438 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 1.03; 1.31; 0.83 ...  LDD1438 
Aconitate hydratase, mitochondrial (ACO2) LDTP10982 0.13  LDD1481 
Adenosine kinase (ADK) LDTP04689 1.28  LDD1438 
ADP-ribose glycohydrolase MACROD1 (MACROD1) LDTP11059 1.23  LDD1481 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 0.73  LDD1481 
Aldehyde dehydrogenase, mitochondrial (ALDH2) LDTP02074 0.88  LDD1481 
Aldo-keto reductase family 1 member B1 (AKR1B1) LDTP02765 3.72  LDD1438 
All trans-polyprenyl-diphosphate synthase PDSS2 (PDSS2) LDTP08401 0.91  LDD1481 
Alpha-adducin (ADD1) LDTP03770 0.88  LDD1481 
AMP deaminase 2 (AMPD2) LDTP05289 1.29  LDD1438 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 1.60  LDD1438 
Aspartyl aminopeptidase (DNPEP) LDTP13527 0.76  LDD1481 
ATP-dependent 6-phosphofructokinase, platelet type (PFKP) LDTP05314 1.28  LDD1438 
ATPase WRNIP1 (WRNIP1) LDTP10801 1.77  LDD1438 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 0.64  LDD1439 
Bleomycin hydrolase (BLMH) LDTP05992 0.99  LDD1439 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 0.48; 0.46  LDD1438 
Caspase-8 (CASP8) LDTP06211 0.96  LDD1438 
Cathepsin B (CTSB) LDTP02223 1.06; 1.15  LDD1438 
Cathepsin D (CTSD) LDTP02198 1.32  LDD1438 
Cathepsin Z (CTSZ) LDTP13147 0.90; 1.16  LDD1438 
Cell cycle checkpoint control protein RAD9A (RAD9A) LDTP10929 0.83  LDD1438 
Cleavage and polyadenylation specificity factor subunit 3 (CPSF3) LDTP13449 1.09  LDD1438 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 1.05  LDD1438 
Cyclin-dependent kinase inhibitor 3 (CDKN3) LDTP06603 1.66  LDD1439 
Cytidine deaminase (CDA) LDTP03642 2.61  LDD1438 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 7.84  LDD1439 
Deaminated glutathione amidase (NIT1) LDTP15311 8.66  LDD1438 
Deoxycytidine kinase (DCK) LDTP03400 1.16  LDD1438 
DNA dC->dU-editing enzyme APOBEC-3C (APOBEC3C) LDTP12539 0.92  LDD1481 
DNA repair protein RAD50 (RAD50) LDTP09912 3.23  LDD1438 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 0.94  LDD1481 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 0.45  LDD1438 
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) LDTP04103 2.29  LDD1438 
Dual specificity mitogen-activated protein kinase kinase 4 (MAP2K4) LDTP04077 1.52  LDD1438 
Dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7) LDTP00414 0.81  LDD1481 
Dual specificity protein phosphatase 12 (DUSP12) LDTP13663 0.76  LDD1438 
Dynamin-1-like protein (DNM1L) LDTP00273 2.74  LDD1439 
Dynamin-2 (DNM2) LDTP04374 1.31  LDD1438 
E3 SUMO-protein ligase PIAS4 (PIAS4) LDTP08808 0.83  LDD1481 
E3 ubiquitin-protein ligase BRE1B (RNF40) LDTP01141 1.26  LDD1481 
Elongation factor 2 (EEF2) LDTP02672 1.50; 0.90  LDD1438 
Elongation factor G, mitochondrial (GFM1) LDTP10774 1.45  LDD1438 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 0.39  LDD1439 
Enoyl-CoA delta isomerase 2 (ECI2) LDTP01245 2.86  LDD1438 
ERO1-like protein alpha (ERO1A) LDTP10386 1.17; 1.09; 1.31  LDD1438 
Eukaryotic translation initiation factor 3 subunit F (EIF3F) LDTP00246 1.62  LDD1438 
Fructose-2,6-bisphosphatase TIGAR (TIGAR) LDTP12405 0.59  LDD1481 
Galactokinase (GALK1) LDTP04424 0.81  LDD1438 
General transcription and DNA repair factor IIH helicase subunit XPB (ERCC3) LDTP03000 1.07  LDD1438 
Glutaredoxin-1 (GLRX) LDTP03786 1.00  LDD1438 
Glutaredoxin-related protein 5, mitochondrial (GLRX5) LDTP08181 0.81  LDD1438 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 0.88  LDD1438 
Glutathione S-transferase P (GSTP1) LDTP02333 1.34  LDD1438 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 0.76  LDD1438 
Glycerol-3-phosphate phosphatase (PGP) LDTP00089 1.01  LDD1438 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 1.21  LDD1438 
GMP reductase 2 (GMPR2) LDTP13080 0.95  LDD1438 
Haloacid dehalogenase-like hydrolase domain-containing 5 (HDHD5) LDTP18330 0.96  LDD1481 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 0.56  LDD1481 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 0.94; 1.02  LDD1438 
Integrin-linked protein kinase (ILK) LDTP05859 1.05  LDD1438 
Isoamyl acetate-hydrolyzing esterase 1 homolog (IAH1) LDTP17082 1.16  LDD1438 
Isochorismatase domain-containing protein 2 (ISOC2) LDTP18123 0.68  LDD1481 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 0.79  LDD1438 
Ketosamine-3-kinase (FN3KRP) LDTP16025 2.22  LDD1438 
Lysine-specific demethylase RSBN1L (RSBN1L) LDTP17384 1.45  LDD1439 
Mannose-1-phosphate guanyltransferase alpha (GMPPA) LDTP10418 1.02  LDD1438 
Medium-chain acyl-CoA ligase ACSF2, mitochondrial (ACSF2) LDTP10177 1.04  LDD1438 
Methionine-R-sulfoxide reductase B2, mitochondrial (MSRB2) LDTP13980 1.23  LDD1481 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 1.01  LDD1481 
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial (ALDH6A1) LDTP05346 0.81  LDD1481 
Mitochondrial coenzyme A diphosphatase NUDT8 (NUDT8) LDTP09598 0.94  LDD1481 
Mitochondrial-processing peptidase subunit beta (PMPCB) LDTP01220 1.32  LDD1481 
Mitogen-activated protein kinase 9 (MAPK9) LDTP04076 0.84  LDD1438 
Mitogen-activated protein kinase kinase kinase 20 (MAP3K20) LDTP12837 1.49  LDD1438 
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) LDTP07651 1.11  LDD1438 
Multifunctional protein CAD (CAD) LDTP03401 0.65  LDD1481 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 1.47  LDD1438 
NmrA-like family domain-containing protein 1 (NMRAL1) LDTP12190 1.32  LDD1438 
Omega-amidase NIT2 (NIT2) LDTP12428 1.02  LDD1438 
Parkinson disease protein 7 (PARK7) LDTP10878 0.83  LDD1439 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) LDTP05912 0.98  LDD1438 
Peroxiredoxin-4 (PRDX4) LDTP05773 1.37  LDD1438 
Peroxiredoxin-5, mitochondrial (PRDX5) LDTP03512 0.69  LDD1438 
Persulfide dioxygenase ETHE1, mitochondrial (ETHE1) LDTP01633 0.84  LDD1438 
Pre-rRNA-processing protein TSR1 homolog (TSR1) LDTP14888 0.98  LDD1438 
Probable ATP-dependent RNA helicase DDX59 (DDX59) LDTP07098 1.24  LDD1438 
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1) LDTP05373 1.46  LDD1438 
Prostaglandin E synthase 3 (PTGES3) LDTP06338 1.84  LDD1438 
Protein arginine N-methyltransferase 1 (PRMT1) LDTP10997 0.88  LDD1438 
Protein disulfide-isomerase (P4HB) LDTP02188 1.05  LDD1438 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 0.99  LDD1438 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 0.99; 0.99  LDD1438 
Protein disulfide-isomerase A6 (PDIA6) LDTP06314 0.91  LDD1438 
Protein phosphatase methylesterase 1 (PPME1) LDTP14092 0.15  LDD1481 
Protein PML (PML) LDTP03496 1.78  LDD1438 
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) LDTP03146 1.00  LDD1438 
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT1) LDTP03152 1.03  LDD1438 
Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 (ALG13) LDTP12313 0.45  LDD1481 
Putative transferase CAF17, mitochondrial (IBA57) LDTP07110 0.73  LDD1481 
Pyruvate carboxylase, mitochondrial (PC) LDTP02576 0.79  LDD1438 
Pyruvate kinase PKM (PKM) LDTP02733 1.05  LDD1439 
Ras-related GTP-binding protein C (RRAGC) LDTP12166 1.11; 1.31  LDD1438 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 4.54  LDD1481 
RNA ligase 1 (RLIG1) LDTP19750 0.33  LDD1481 
Serine--tRNA ligase, cytoplasmic (SARS1) LDTP04265 1.10  LDD1438 
Serine/threonine-protein kinase MRCK beta (CDC42BPB) LDTP14155 1.17  LDD1438 
Serine/threonine-protein kinase Nek9 (NEK9) LDTP09412 0.96  LDD1439 
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D) LDTP06199 1.21  LDD1438 
Serine/threonine-protein phosphatase CPPED1 (CPPED1) LDTP11107 4.54  LDD1438 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 1.20  LDD1438 
Sterol carrier protein 2 (SCP2) LDTP03163 1.01  LDD1438 
Tensin-3 (TNS3) LDTP07317 1.32  LDD1438 
Thioredoxin (TXN) LDTP02502 1.14  LDD1438 
Thioredoxin domain-containing protein 12 (TXNDC12) LDTP01707 1.04  LDD1481 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 1.00; 0.96  LDD1438 
Thioredoxin, mitochondrial (TXN2) LDTP10973 0.48  LDD1481 
Thymidine kinase, cytosolic (TK1) LDTP02022 1.28; 1.05  LDD1438 
Thymidylate kinase (DTYMK) LDTP03258 0.19  LDD1481 
Thymidylate synthase (TYMS) LDTP02055 0.68  LDD1481 
Transmembrane protease serine 12 (TMPRSS12) LDTP15306 0.78  LDD1439 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 1.44; 1.48; 1.21  LDD1438 
Tubulin alpha-4A chain (TUBA4A) LDTP05075 1.26; 1.42; 1.52  LDD1438 
Tudor-interacting repair regulator protein (NUDT16L1) LDTP11111 1.15  LDD1438 
Ubiquitin carboxyl-terminal hydrolase 16 (USP16) LDTP14159 0.84  LDD1438 
Ubiquitin-conjugating enzyme E2 L3 (UBE2L3) LDTP05070 9.75  LDD1438 
Ubiquitin-conjugating enzyme E2 S (UBE2S) LDTP06621 3.44  LDD1439 
Ubiquitin-like modifier-activating enzyme 6 (UBA6) LDTP00013 0.64  LDD1481 
Ubiquitin/ISG15-conjugating enzyme E2 L6 (UBE2L6) LDTP00481 0.47  LDD1481 
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (OGT) LDTP00601 0.94  LDD1438 
Uridine phosphorylase 1 (UPP1) LDTP06643 2.19  LDD1438 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 0.76  LDD1481 
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP1) LDTP12960 0.97  LDD1438 
------------------------------------------------------------------------------------
⏷ Show the Full List of 145 Enzyme
24 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 1.01  LDD1438 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 0.93  LDD1438 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 0.96  LDD1438 
Chloride intracellular channel protein 6 (CLIC6) LDTP10642 0.44  LDD1481 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 1.01  LDD1481 
Exportin-1 (XPO1) LDTP00501 3.12; 0.64  LDD1438 
Exportin-2 (CSE1L) LDTP04662 1.60  LDD1438 
G2/mitotic-specific cyclin-B1 (CCNB1) LDTP02735 0.48  LDD1481 
Gasdermin-D (GSDMD) LDTP04801 1.62  LDD1438 
Importin-7 (IPO7) LDTP01574 20.00  LDD1439 
Nuclear cap-binding protein subunit 1 (NCBP1) LDTP05591 0.75  LDD1481 
Nuclear pore complex protein Nup214 (NUP214) LDTP03777 1.37  LDD1438 
Nuclear pore complex protein Nup50 (NUP50) LDTP13498 0.81  LDD1481 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 1.52  LDD1438 
Nucleoporin NUP35 (NUP35) LDTP09204 1.31  LDD1438 
Pinin (PNN) LDTP11855 0.92  LDD1438 
Protein SEC13 homolog (SEC13) LDTP04707 1.04  LDD1438 
Signal recognition particle 9 kDa protein (SRP9) LDTP04259 0.72  LDD1438 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 4.66  LDD1439 
Sorting nexin-6 (SNX6) LDTP13661 1.99  LDD1438 
Thioredoxin domain-containing protein 17 (TXNDC17) LDTP11103 0.97  LDD1438 
THO complex subunit 6 homolog (THOC6) LDTP08315 0.91  LDD1438 
Unconventional myosin-Ic (MYO1C) LDTP00196 2.50  LDD1438 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 1.44  LDD1481 
------------------------------------------------------------------------------------
⏷ Show the Full List of 24 Transporter and channel
10 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
CDKN2A-interacting protein (CDKN2AIP) LDTP12792 3.30  LDD1438 
Chromatin accessibility complex protein 1 (CHRAC1) LDTP12507 12.21  LDD1439 
COUP transcription factor 2 (NR2F2) LDTP03280 0.80  LDD1481 
eIF5-mimic protein 2 (BZW1) LDTP07940 1.83  LDD1438 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 1.28  LDD1438 
Nucleus accumbens-associated protein 1 (NACC1) LDTP10756 20.00  LDD1438 
Recombining binding protein suppressor of hairless (RBPJ) LDTP05485 1.55  LDD1438 
Signal transducer and activator of transcription 1-alpha/beta (STAT1) LDTP03969 1.19  LDD1438 
SWI/SNF complex subunit SMARCC2 (SMARCC2) LDTP09311 1.82  LDD1438 
Zinc finger protein 217 (ZNF217) LDTP01191 0.57  LDD1439 
------------------------------------------------------------------------------------
⏷ Show the Full List of 10 Transcription factor
119 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
55 kDa erythrocyte membrane protein (MPP1) LDTP05233 2.03  LDD1438 
A-kinase anchor protein 8-like (AKAP8L) LDTP13591 1.36  LDD1438 
Actin filament-associated protein 1 (AFAP1) LDTP08885 1.53  LDD1438 
Acyl-CoA-binding domain-containing protein 6 (ACBD6) LDTP15861 0.53  LDD1481 
AH receptor-interacting protein (AIP) LDTP00202 1.07  LDD1438 
Alpha-actinin-1 (ACTN1) LDTP02631 5.24  LDD1438 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 1.39; 1.20  LDD1438 
Anillin (ANLN) LDTP12443 1.31  LDD1438 
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1) LDTP10657 0.52  LDD1481 
Ashwin (C2orf49) LDTP15896 1.02  LDD1481 
Ataxin-7-like protein 3B (ATXN7L3B) LDTP15730 1.14  LDD1438 
BRISC and BRCA1-A complex member 1 (BABAM1) LDTP12737 1.74  LDD1438 
Calponin-2 (CNN2) LDTP10864 1.18; 1.20  LDD1438 
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) LDTP02511 2.35  LDD1438 
Cleavage stimulation factor subunit 2 (CSTF2) LDTP03665 2.64  LDD1438 
Cleavage stimulation factor subunit 2 tau variant (CSTF2T) LDTP11718 1.92  LDD1438 
Condensin complex subunit 1 (NCAPD2) LDTP06281 1.19  LDD1438 
Condensin complex subunit 2 (NCAPH) LDTP06268 1.23  LDD1438 
Coronin-1C (CORO1C) LDTP13580 1.25; 1.75  LDD1438 
Crk-like protein (CRKL) LDTP04092 1.11  LDD1438 
Cyclin-H (CCNH) LDTP04487 1.18  LDD1481 
Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) LDTP14250 0.67  LDD1481 
Cytosolic Fe-S cluster assembly factor NUBP1 (NUBP1) LDTP04560 1.47  LDD1438 
Cytosolic iron-sulfur assembly component 2B (CIAO2B) LDTP13979 1.14  LDD1438 
Dedicator of cytokinesis protein 7 (DOCK7) LDTP10613 1.39  LDD1438 
Disks large-associated protein 5 (DLGAP5) LDTP06378 1.31  LDD1438 
DNA mismatch repair protein Msh2 (MSH2) LDTP04028 1.25  LDD1438 
Dynactin subunit 1 (DCTN1) LDTP06082 1.13  LDD1438 
Dynactin subunit 4 (DCTN4) LDTP13402 0.66  LDD1481 
Dynamin-binding protein (DNMBP) LDTP07755 1.38  LDD1438 
EF-hand domain-containing protein D2 (EFHD2) LDTP15701 1.22  LDD1438 
Enhancer of mRNA-decapping protein 3 (EDC3) LDTP10299 0.63  LDD1438 
Eukaryotic translation initiation factor 3 subunit J (EIF3J) LDTP01320 1.34  LDD1438 
Eukaryotic translation initiation factor 3 subunit M (EIF3M) LDTP07947 6.88  LDD1438 
Formin-binding protein 1-like (FNBP1L) LDTP07088 1.38  LDD1438 
GrpE protein homolog 1, mitochondrial (GRPEL1) LDTP12144 3.92  LDD1438 
H/ACA ribonucleoprotein complex subunit 2 (NHP2) LDTP12754 0.92  LDD1438 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 0.91  LDD1438 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 0.93  LDD1439 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 1.04  LDD1481 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 0.86  LDD1481 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 1.72  LDD1439 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 1.31  LDD1438 
Hippocalcin-like protein 1 (HPCAL1) LDTP03841 2.70  LDD1438 
Host cell factor 1 (HCFC1) LDTP04434 0.47  LDD1481 
Hsp70-binding protein 1 (HSPBP1) LDTP12914 1.98  LDD1439 
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) LDTP00463 1.19  LDD1438 
Inverted formin-2 (INF2) LDTP06681 1.27  LDD1438 
Kinetochore protein NDC80 homolog (NDC80) LDTP00431 1.02  LDD1438 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 1.23  LDD1438 
LanC-like protein 2 (LANCL2) LDTP12571 1.24  LDD1439 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 1.58; 2.56  LDD1438 
Large ribosomal subunit protein eL30 (RPL30) LDTP05021 2.05  LDD1438 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 1.58  LDD1438 
Large ribosomal subunit protein uL16 (RPL10) LDTP03395 0.95  LDD1439 
Large ribosomal subunit protein uL3 (RPL3) LDTP03865 1.14  LDD1438 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 1.48  LDD1438 
Leucine-rich repeat-containing protein 41 (LRRC41) LDTP06362 0.75  LDD1481 
LIM and calponin homology domains-containing protein 1 (LIMCH1) LDTP13705 0.54  LDD1481 
LIM domain only protein 7 (LMO7) LDTP09650 0.82  LDD1481 
Mediator of RNA polymerase II transcription subunit 17 (MED17) LDTP12669 1.28  LDD1438 
Mediator of RNA polymerase II transcription subunit 9 (MED9) LDTP16117 0.75  LDD1481 
Mini-chromosome maintenance complex-binding protein (MCMBP) LDTP11197 0.60  LDD1481 
MMS19 nucleotide excision repair protein homolog (MMS19) LDTP10843 1.44  LDD1438 
MOB-like protein phocein (MOB4) LDTP13964 2.29  LDD1438 
Multivesicular body subunit 12A (MVB12A) LDTP10284 1.49  LDD1438 
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (NFU1) LDTP13622 0.94  LDD1481 
Nuclear migration protein nudC (NUDC) LDTP13817 1.15  LDD1438 
NudC domain-containing protein 1 (NUDCD1) LDTP10781 3.22  LDD1438 
Pescadillo homolog (PES1) LDTP00306 0.91  LDD1481 
Plastin-3 (PLS3) LDTP02692 1.00  LDD1438 
Plectin (PLEC) LDTP06330 1.28  LDD1438 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 0.70; 1.19  LDD1438 
Polymerase delta-interacting protein 2 (POLDIP2) LDTP13906 1.21  LDD1481 
Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 1.29  LDD1438 
Proliferation marker protein Ki-67 (MKI67) LDTP04078 1.03  LDD1481 
Proteasome activator complex subunit 1 (PSME1) LDTP05484 1.67  LDD1438 
Proteasome activator complex subunit 4 (PSME4) LDTP06250 20.00  LDD1438 
Protein diaphanous homolog 1 (DIAPH1) LDTP01011 1.21  LDD1438 
Protein lin-7 homolog C (LIN7C) LDTP12638 5.55  LDD1438 
Protein misato homolog 1 (MSTO1) LDTP11239 1.66  LDD1439 
Protein PAXX (PAXX) LDTP11235 2.15  LDD1438 
Protein S100-A11 (S100A11) LDTP03620 20.00  LDD1438 
Protein unc-45 homolog A (UNC45A) LDTP11890 0.81  LDD1438 
RAB7A-interacting MON1-CCZ1 complex subunit 1 (RIMOC1) LDTP14351 1.56  LDD1438 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 1.53  LDD1438 
Reticulon-4 (RTN4) LDTP12412 1.35  LDD1438 
Ribosomal protein eL42-like (RPL36AL) LDTP15677 1.02  LDD1438 
Serine/threonine-protein phosphatase 4 regulatory subunit 2 (PPP4R2) LDTP12800 0.78  LDD1481 
Serpin H1 (SERPINH1) LDTP04363 1.29  LDD1438 
Sister chromatid cohesion protein PDS5 homolog A (PDS5A) LDTP06684 1.27  LDD1438 
Small ribosomal subunit protein eS27 (RPS27) LDTP03987 1.24  LDD1438 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 0.84  LDD1438 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 1.06  LDD1438 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 0.76; 0.91  LDD1438 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 1.21  LDD1438 
SNW domain-containing protein 1 (SNW1) LDTP05930 1.10  LDD1439 
Stalled ribosome sensor GCN1 (GCN1) LDTP09821 0.68  LDD1481 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 1.57  LDD1438 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 1.16  LDD1438 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 0.86  LDD1438 
T-complex protein 1 subunit eta (CCT7) LDTP10990 1.41  LDD1438 
T-complex protein 1 subunit theta (CCT8) LDTP04390 0.96  LDD1438 
Targeting protein for Xklp2 (TPX2) LDTP13583 1.17  LDD1481 
TBC1 domain family member 23 (TBC1D23) LDTP12651 3.45  LDD1438 
Telomere-associated protein RIF1 (RIF1) LDTP07205 1.21  LDD1481 
THUMP domain-containing protein 1 (THUMPD1) LDTP12780 1.23  LDD1438 
Trafficking protein particle complex subunit 4 (TRAPPC4) LDTP13837 0.96  LDD1438 
Transcription initiation factor IIA subunit 2 (GTF2A2) LDTP04517 1.21  LDD1439 
Treacle protein (TCOF1) LDTP05867 1.57; 1.54  LDD1438 
Tropomodulin-3 (TMOD3) LDTP18494 5.18  LDD1438 
Tubulin beta chain (TUBB) LDTP02205 1.99; 0.78  LDD1439 
Uncharacterized protein C3orf38 (C3orf38) LDTP17182 0.66  LDD1481 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 1.03  LDD1481 
WD repeat domain phosphoinositide-interacting protein 3 (WDR45B) LDTP07037 0.84  LDD1481 
Wings apart-like protein homolog (WAPL) LDTP08094 0.97  LDD1481 
WW domain-containing adapter protein with coiled-coil (WAC) LDTP11191 0.93  LDD1438 
Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) LDTP08018 0.86  LDD1481 
ZW10 interactor (ZWINT) LDTP01532 1.45  LDD1439 
------------------------------------------------------------------------------------
⏷ Show the Full List of 119 Other

Full Information of The Labelling Profiles of This Competitor

IA-alkyne
 Probe Info 
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 100 uM
Quantitative Method Isotope tag
Competitor Name Fragment41
Competitor Concentration 500 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cell lysate (MDA-MB-231)
Interaction Atlas ID  LDD1438  Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 100 uM
Quantitative Method Isotope tag
Competitor Name Fragment41
Competitor Concentration 500 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Lymph node
Disease Model Burkitt lymphoma [ICD-11:2A85]
Model Name Human burkitt lymphoma cell lysate (Ramos)
Interaction Atlas ID  LDD1439  Download The Altas
  
Experiment 3 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 100 uM
Quantitative Method Isotope tag
Competitor Name Fragment41
Competitor Concentration 200 uM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cells (MDA-MB-231)
Interaction Atlas ID  LDD1481  Download The Altas

References

1 Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.