Details of the Target

General Information of Target

Target ID LDTP13705
Target Name LIM and calponin homology domains-containing protein 1 (LIMCH1)
Gene Name LIMCH1
Gene ID 22998
Synonyms
KIAA1102; LIM and calponin homology domains-containing protein 1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MESLLENPVRAVLYLKELTAIVQNQQSLIHTQRERIDELERRLDELSAENRSLWEHQQLL
QAQPPPGLVPPSSAPLPAAPATAPAAAARAQEPLQDQGQRSAAAPHPAPDRPPRQHHGQL
LEQPQRGPGSRAHTPQSPHKHLGTQGAVTDKEKERPPSCCAAAGALLQHKSPSALGKGVL
SRRPENETVLHQFCCPAADACSDLASQSDGSCTQAGGGMEDSVVAAAAVAAGRPSAHAPK
AQAQELQEEEERPGAGAASPRAGPQHKASPGRQQPALATALCPHAPAASDYELSLDLKNK
QIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSPT
AESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTW
SLKTMCSLRESGAYQLHQALQAAAGPPGLEAEGRAPESAGPGPGDDAAETPGLPPAHSGT
LMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPEA
PAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSS
STSTKSAKSGSEASASASKDALQAMILSLPRYHCENPASCKSPTLSTDTLRKRLYRIGLN
LFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDCV
VDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIF
ILAFAIILLNTDMYSPNIKPDRKMMLEDFIRNLRGVDDGADIPRELVVGIYERIQQKELK
SNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFND
LLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFC
ALGSDEMQKFVEDLKESIAEVTELEQIRIEWELEKQQGTKTLSFKPCGAQGDPQSKQGSP
TAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPLP
PPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSP
VKVTHQPPLPPPPPPYNHPHQFCPPGSLLHGHRYSSGSRSLV
Target Bioclass
Other
Family
LIMCH1 family
Subcellular location
Cytoplasm, cytoskeleton, stress fiber
Function
Actin stress fibers-associated protein that activates non-muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration.
Uniprot ID
Q9UPQ0
Ensemble ID
ENST00000313860.12
HGNC ID
HGNC:29191

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
JURKAT Deletion: p.I76LfsTer11 .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 17 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K431(6.49); K552(10.00)  LDD0277  [1]
AHL-Pu-1
 Probe Info  		C333(4.67); C577(4.27)  LDD0170  [2]
DBIA
 Probe Info  		C1067(1.19); C1070(1.19); C140(0.98); C669(0.86)  LDD0078  [3]
5E-2FA
 Probe Info  		H906(0.00); H969(0.00)  LDD2235  [4]
m-APA
 Probe Info  		H969(0.00); H906(0.00)  LDD2231  [4]
IA-alkyne
 Probe Info  		C863(0.00); C182(0.00); C55(0.00); C333(0.00)  LDD0162  [5]
IPM
 Probe Info  		C140(0.00); C3(0.00); C669(0.00)  LDD0025  [6]
JW-RF-010
 Probe Info  		C669(0.00); C3(0.00)  LDD0026  [6]
NAIA_4
 Probe Info  		C55(0.00); C140(0.00); C182(0.00); C333(0.00)  LDD2226  [7]
TFBX
 Probe Info  		C333(0.00); C3(0.00)  LDD0027  [6]
WYneO
 Probe Info  		N.A.  LDD0022  [8]
Acrolein
 Probe Info  		C577(0.00); C182(0.00); H599(0.00); H969(0.00)  LDD0217  [9]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [9]
Methacrolein
 Probe Info  		C863(0.00); C577(0.00); C182(0.00)  LDD0218  [9]
NAIA_5
 Probe Info  		N.A.  LDD2223  [7]
HHS-465
 Probe Info  		Y541(0.00); Y269(0.00); K539(0.00)  LDD2240  [10]
HHS-475
 Probe Info  		Y541(1.15)  LDD2238  [11]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C333(4.67); C577(4.27)  LDD0170  [2]
 LDCM0214  AC1 PaTu 8988t C1070(1.10); C669(0.64); C1013(0.97); C1016(0.97)  LDD1093  [3]
 LDCM0215  AC10 PaTu 8988t C1070(1.65); C1013(0.90); C1016(0.90); C140(1.37)  LDD1094  [3]
 LDCM0216  AC100 PaTu 8988t C1013(1.23); C1016(1.23); C140(1.05); C182(1.01)  LDD1095  [3]
 LDCM0217  AC101 PaTu 8988t C1013(1.05); C1016(1.05); C140(0.99); C182(0.87)  LDD1096  [3]
 LDCM0218  AC102 PaTu 8988t C1013(0.92); C1016(0.92); C140(1.19); C182(0.95)  LDD1097  [3]
 LDCM0219  AC103 PaTu 8988t C1013(1.01); C1016(1.01); C140(1.31); C182(1.65)  LDD1098  [3]
 LDCM0220  AC104 PaTu 8988t C1013(1.01); C1016(1.01); C140(0.96); C182(1.01)  LDD1099  [3]
 LDCM0221  AC105 PaTu 8988t C1013(0.98); C1016(0.98); C140(1.06); C182(1.36)  LDD1100  [3]
 LDCM0222  AC106 PaTu 8988t C1013(1.09); C1016(1.09); C140(1.20); C182(1.13)  LDD1101  [3]
 LDCM0223  AC107 PaTu 8988t C1013(1.11); C1016(1.11); C140(0.98); C182(1.16)  LDD1102  [3]
 LDCM0224  AC108 PaTu 8988t C1013(1.19); C1016(1.19); C140(1.19); C182(1.25)  LDD1103  [3]
 LDCM0225  AC109 PaTu 8988t C1013(0.91); C1016(0.91); C140(1.31); C182(2.10)  LDD1104  [3]
 LDCM0226  AC11 PaTu 8988t C1070(1.52); C1013(1.05); C1016(1.05); C140(1.87)  LDD1105  [3]
 LDCM0227  AC110 PaTu 8988t C1013(0.92); C1016(0.92); C140(1.21); C182(1.43)  LDD1106  [3]
 LDCM0228  AC111 PaTu 8988t C1013(1.19); C1016(1.19); C140(1.56); C182(2.26)  LDD1107  [3]
 LDCM0229  AC112 PaTu 8988t C1013(1.08); C1016(1.08); C140(1.20); C182(1.50)  LDD1108  [3]
 LDCM0230  AC113 PaTu 8988t C1013(1.08); C1016(1.08); C140(0.84); C182(1.06)  LDD1109  [3]
 LDCM0231  AC114 PaTu 8988t C1013(1.14); C1016(1.14); C140(0.82); C182(0.98)  LDD1110  [3]
 LDCM0232  AC115 PaTu 8988t C1013(1.04); C1016(1.04); C140(0.82); C182(1.12)  LDD1111  [3]
 LDCM0233  AC116 PaTu 8988t C1013(1.18); C1016(1.18); C140(0.98); C182(1.03)  LDD1112  [3]
 LDCM0234  AC117 PaTu 8988t C1013(1.09); C1016(1.09); C140(0.88); C182(1.20)  LDD1113  [3]
 LDCM0235  AC118 PaTu 8988t C1013(1.05); C1016(1.05); C140(0.92); C182(0.93)  LDD1114  [3]
 LDCM0236  AC119 PaTu 8988t C1013(1.09); C1016(1.09); C140(1.05); C182(0.97)  LDD1115  [3]
 LDCM0237  AC12 PaTu 8988t C1070(1.10); C1013(0.87); C1016(0.87); C140(1.69)  LDD1116  [3]
 LDCM0238  AC120 PaTu 8988t C1013(1.27); C1016(1.27); C140(0.88); C182(0.73)  LDD1117  [3]
 LDCM0239  AC121 PaTu 8988t C1013(1.31); C1016(1.31); C140(1.07); C182(0.86)  LDD1118  [3]
 LDCM0240  AC122 PaTu 8988t C1013(1.06); C1016(1.06); C140(0.82); C182(0.85)  LDD1119  [3]
 LDCM0241  AC123 PaTu 8988t C1013(1.07); C1016(1.07); C140(0.94); C182(0.73)  LDD1120  [3]
 LDCM0242  AC124 PaTu 8988t C1013(1.05); C1016(1.05); C140(1.08); C182(0.82)  LDD1121  [3]
 LDCM0243  AC125 PaTu 8988t C1013(0.95); C1016(0.95); C140(1.09); C182(1.15)  LDD1122  [3]
 LDCM0244  AC126 PaTu 8988t C1013(1.02); C1016(1.02); C140(0.83); C182(0.92)  LDD1123  [3]
 LDCM0245  AC127 PaTu 8988t C1013(1.09); C1016(1.09); C140(1.15); C182(0.78)  LDD1124  [3]
 LDCM0246  AC128 PaTu 8988t C1067(1.37); C577(1.30); C1070(1.37); C1013(0.91)  LDD1125  [3]
 LDCM0247  AC129 PaTu 8988t C1067(1.35); C577(1.33); C1070(1.35); C1013(0.85)  LDD1126  [3]
 LDCM0249  AC130 PaTu 8988t C1067(1.07); C577(1.31); C1070(1.07); C1013(0.83)  LDD1128  [3]
 LDCM0250  AC131 PaTu 8988t C1067(1.04); C577(1.13); C1070(1.04); C1013(0.99)  LDD1129  [3]
 LDCM0251  AC132 PaTu 8988t C1067(0.98); C577(1.15); C1070(0.98); C1013(0.83)  LDD1130  [3]
 LDCM0252  AC133 PaTu 8988t C1067(1.13); C577(1.29); C1070(1.13); C1013(0.85)  LDD1131  [3]
 LDCM0253  AC134 PaTu 8988t C1067(1.02); C577(1.21); C1070(1.02); C1013(1.01)  LDD1132  [3]
 LDCM0254  AC135 PaTu 8988t C1067(1.16); C577(1.36); C1070(1.16); C1013(0.94)  LDD1133  [3]
 LDCM0255  AC136 PaTu 8988t C1067(1.32); C577(1.31); C1070(1.32); C1013(0.95)  LDD1134  [3]
 LDCM0256  AC137 PaTu 8988t C1067(1.24); C577(1.26); C1070(1.24); C1013(0.84)  LDD1135  [3]
 LDCM0257  AC138 PaTu 8988t C1067(1.10); C577(1.41); C1070(1.10); C1013(1.05)  LDD1136  [3]
 LDCM0258  AC139 PaTu 8988t C1067(1.33); C577(1.24); C1070(1.33); C1013(1.05)  LDD1137  [3]
 LDCM0259  AC14 PaTu 8988t C1070(1.09); C1013(1.03); C1016(1.03); C140(2.00)  LDD1138  [3]
 LDCM0260  AC140 PaTu 8988t C1067(1.10); C577(1.33); C1070(1.10); C1013(0.71)  LDD1139  [3]
 LDCM0261  AC141 PaTu 8988t C1067(1.26); C577(1.17); C1070(1.26); C1013(0.82)  LDD1140  [3]
 LDCM0262  AC142 PaTu 8988t C1067(1.02); C577(1.23); C1070(1.02); C1013(0.86)  LDD1141  [3]
 LDCM0263  AC143 PaTu 8988t C669(1.48); C1013(0.89); C1016(0.89); C140(1.03)  LDD1142  [3]
 LDCM0264  AC144 PaTu 8988t C669(1.57); C1013(0.74); C1016(0.74); C140(1.12)  LDD1143  [3]
 LDCM0265  AC145 PaTu 8988t C669(1.26); C1013(0.80); C1016(0.80); C140(0.99)  LDD1144  [3]
 LDCM0266  AC146 PaTu 8988t C669(1.61); C1013(0.92); C1016(0.92); C140(1.08)  LDD1145  [3]
 LDCM0267  AC147 PaTu 8988t C669(1.53); C1013(1.16); C1016(1.16); C140(1.11)  LDD1146  [3]
 LDCM0268  AC148 PaTu 8988t C669(1.95); C1013(0.86); C1016(0.86); C140(1.65)  LDD1147  [3]
 LDCM0269  AC149 PaTu 8988t C669(1.84); C1013(1.11); C1016(1.11); C140(1.87)  LDD1148  [3]
 LDCM0270  AC15 PaTu 8988t C1070(1.56); C1013(0.89); C1016(0.89); C140(2.53)  LDD1149  [3]
 LDCM0271  AC150 PaTu 8988t C669(1.92); C1013(0.93); C1016(0.93); C140(1.74)  LDD1150  [3]
 LDCM0272  AC151 PaTu 8988t C669(2.22); C1013(1.05); C1016(1.05); C140(2.37)  LDD1151  [3]
 LDCM0273  AC152 PaTu 8988t C669(1.75); C1013(0.99); C1016(0.99); C140(1.40)  LDD1152  [3]
 LDCM0274  AC153 PaTu 8988t C669(2.06); C1013(1.02); C1016(1.02); C140(1.96)  LDD1153  [3]
 LDCM0621  AC154 PaTu 8988t C669(1.88); C1013(1.10); C1016(1.10); C140(2.47)  LDD2166  [3]
 LDCM0622  AC155 PaTu 8988t C669(1.91); C1013(0.82); C1016(0.82); C140(1.79)  LDD2167  [3]
 LDCM0623  AC156 PaTu 8988t C669(1.77); C1013(1.04); C1016(1.04); C140(1.63)  LDD2168  [3]
 LDCM0624  AC157 PaTu 8988t C669(2.38); C1013(0.76); C1016(0.76); C140(2.18)  LDD2169  [3]
 LDCM0276  AC17 PaTu 8988t C1067(0.99); C577(0.98); C863(0.88); C1070(1.07)  LDD1155  [3]
 LDCM0277  AC18 PaTu 8988t C1067(1.17); C577(0.99); C863(1.41); C1070(1.15)  LDD1156  [3]
 LDCM0278  AC19 PaTu 8988t C1067(1.20); C577(1.03); C863(0.94); C1070(1.18)  LDD1157  [3]
 LDCM0279  AC2 PaTu 8988t C1070(1.31); C669(0.38); C1013(1.11); C1016(1.11)  LDD1158  [3]
 LDCM0280  AC20 PaTu 8988t C1067(1.97); C577(1.02); C863(0.90); C1070(1.71)  LDD1159  [3]
 LDCM0281  AC21 PaTu 8988t C1067(1.26); C577(0.94); C863(0.96); C1070(1.46)  LDD1160  [3]
 LDCM0282  AC22 PaTu 8988t C1067(1.56); C577(0.97); C863(1.43); C1070(1.63)  LDD1161  [3]
 LDCM0283  AC23 PaTu 8988t C1067(1.27); C577(1.21); C863(1.55); C1070(1.32)  LDD1162  [3]
 LDCM0284  AC24 PaTu 8988t C1067(1.32); C577(1.11); C863(1.53); C1070(1.21)  LDD1163  [3]
 LDCM0285  AC25 PaTu 8988t C140(1.17); C182(1.16)  LDD1164  [3]
 LDCM0286  AC26 PaTu 8988t C140(1.12); C182(1.15)  LDD1165  [3]
 LDCM0287  AC27 PaTu 8988t C140(1.44); C182(1.07)  LDD1166  [3]
 LDCM0288  AC28 PaTu 8988t C140(2.38); C182(1.33)  LDD1167  [3]
 LDCM0289  AC29 PaTu 8988t C140(1.19); C182(0.91)  LDD1168  [3]
 LDCM0290  AC3 PaTu 8988t C1070(1.18); C669(0.56); C1013(1.07); C1016(1.07)  LDD1169  [3]
 LDCM0291  AC30 PaTu 8988t C140(1.11); C182(1.06)  LDD1170  [3]
 LDCM0292  AC31 PaTu 8988t C140(1.04); C182(1.17)  LDD1171  [3]
 LDCM0293  AC32 PaTu 8988t C140(1.36); C182(1.73)  LDD1172  [3]
 LDCM0294  AC33 PaTu 8988t C140(1.70); C182(1.64)  LDD1173  [3]
 LDCM0295  AC34 PaTu 8988t C140(0.93); C182(1.35)  LDD1174  [3]
 LDCM0296  AC35 PaTu 8988t C1067(0.89); C863(1.23); C1070(0.89); C669(1.26)  LDD1175  [3]
 LDCM0297  AC36 PaTu 8988t C1067(0.85); C863(2.04); C1070(0.85); C669(1.41)  LDD1176  [3]
 LDCM0298  AC37 PaTu 8988t C1067(1.25); C863(1.66); C1070(1.25); C669(1.31)  LDD1177  [3]
 LDCM0299  AC38 PaTu 8988t C1067(1.27); C863(1.44); C1070(1.27); C669(1.37)  LDD1178  [3]
 LDCM0300  AC39 PaTu 8988t C1067(1.33); C863(1.69); C1070(1.33); C669(1.61)  LDD1179  [3]
 LDCM0301  AC4 PaTu 8988t C1070(1.09); C669(0.43); C1013(0.85); C1016(0.85)  LDD1180  [3]
 LDCM0302  AC40 PaTu 8988t C1067(1.29); C863(1.50); C1070(1.29); C669(1.60)  LDD1181  [3]
 LDCM0303  AC41 PaTu 8988t C1067(1.20); C863(1.21); C1070(1.20); C669(1.30)  LDD1182  [3]
 LDCM0304  AC42 PaTu 8988t C1067(1.74); C863(1.00); C1070(1.74); C669(1.41)  LDD1183  [3]
 LDCM0305  AC43 PaTu 8988t C1067(1.06); C863(1.36); C1070(1.06); C669(1.21)  LDD1184  [3]
 LDCM0306  AC44 PaTu 8988t C1067(1.44); C863(1.45); C1070(1.44); C669(1.77)  LDD1185  [3]
 LDCM0307  AC45 PaTu 8988t C1067(1.25); C863(1.17); C1070(1.25); C669(1.35)  LDD1186  [3]
 LDCM0308  AC46 PaTu 8988t C577(0.57); C669(1.40); C1013(1.08); C1016(1.08)  LDD1187  [3]
 LDCM0309  AC47 PaTu 8988t C577(0.92); C669(1.09); C1013(0.97); C1016(0.97)  LDD1188  [3]
 LDCM0310  AC48 PaTu 8988t C577(0.95); C669(1.20); C1013(0.95); C1016(0.95)  LDD1189  [3]
 LDCM0311  AC49 PaTu 8988t C577(1.08); C669(1.31); C1013(1.31); C1016(1.31)  LDD1190  [3]
 LDCM0312  AC5 PaTu 8988t C1070(1.13); C669(0.71); C1013(1.04); C1016(1.04)  LDD1191  [3]
 LDCM0313  AC50 PaTu 8988t C577(1.10); C669(1.44); C1013(0.97); C1016(0.97)  LDD1192  [3]
 LDCM0314  AC51 PaTu 8988t C577(0.85); C669(1.12); C1013(0.48); C1016(0.48)  LDD1193  [3]
 LDCM0315  AC52 PaTu 8988t C577(1.03); C669(1.26); C1013(1.06); C1016(1.06)  LDD1194  [3]
 LDCM0316  AC53 PaTu 8988t C577(1.13); C669(1.33); C1013(1.20); C1016(1.20)  LDD1195  [3]
 LDCM0317  AC54 PaTu 8988t C577(1.42); C669(1.99); C1013(1.31); C1016(1.31)  LDD1196  [3]
 LDCM0318  AC55 PaTu 8988t C577(0.96); C669(1.61); C1013(0.69); C1016(0.69)  LDD1197  [3]
 LDCM0319  AC56 PaTu 8988t C577(1.12); C669(2.35); C1013(0.73); C1016(0.73)  LDD1198  [3]
 LDCM0320  AC57 PaTu 8988t C669(1.14); C1013(1.01); C1016(1.01); C140(1.29)  LDD1199  [3]
 LDCM0321  AC58 PaTu 8988t C669(1.21); C1013(0.97); C1016(0.97); C140(1.43)  LDD1200  [3]
 LDCM0322  AC59 PaTu 8988t C669(1.21); C1013(1.03); C1016(1.03); C140(0.89)  LDD1201  [3]
 LDCM0323  AC6 PaTu 8988t C1070(1.13); C1013(0.91); C1016(0.91); C140(1.22)  LDD1202  [3]
 LDCM0324  AC60 PaTu 8988t C669(1.28); C1013(0.89); C1016(0.89); C140(1.23)  LDD1203  [3]
 LDCM0325  AC61 PaTu 8988t C669(0.94); C1013(1.12); C1016(1.12); C140(1.67)  LDD1204  [3]
 LDCM0326  AC62 PaTu 8988t C669(1.06); C1013(0.84); C1016(0.84); C140(0.94)  LDD1205  [3]
 LDCM0327  AC63 PaTu 8988t C669(1.10); C1013(0.93); C1016(0.93); C140(1.35)  LDD1206  [3]
 LDCM0328  AC64 PaTu 8988t C669(1.05); C1013(0.92); C1016(0.92); C140(0.86)  LDD1207  [3]
 LDCM0329  AC65 PaTu 8988t C669(0.90); C1013(1.01); C1016(1.01); C140(0.82)  LDD1208  [3]
 LDCM0330  AC66 PaTu 8988t C669(1.10); C1013(0.87); C1016(0.87); C140(1.05)  LDD1209  [3]
 LDCM0331  AC67 PaTu 8988t C669(1.06); C1013(0.89); C1016(0.89); C140(0.86)  LDD1210  [3]
 LDCM0332  AC68 PaTu 8988t C577(0.79); C1070(1.14); C140(0.77); C182(0.89)  LDD1211  [3]
 LDCM0333  AC69 PaTu 8988t C577(0.83); C1070(0.96); C140(1.03); C182(1.04)  LDD1212  [3]
 LDCM0334  AC7 PaTu 8988t C1070(0.98); C1013(0.95); C1016(0.95); C140(0.89)  LDD1213  [3]
 LDCM0335  AC70 PaTu 8988t C577(0.82); C1070(1.29); C140(0.76); C182(1.06)  LDD1214  [3]
 LDCM0336  AC71 PaTu 8988t C577(0.91); C1070(1.06); C140(0.80); C182(0.84)  LDD1215  [3]
 LDCM0337  AC72 PaTu 8988t C577(0.90); C1070(1.04); C140(0.85); C182(0.83)  LDD1216  [3]
 LDCM0338  AC73 PaTu 8988t C577(0.78); C1070(0.93); C140(0.87); C182(0.84)  LDD1217  [3]
 LDCM0339  AC74 PaTu 8988t C577(0.71); C1070(1.24); C140(0.82); C182(0.97)  LDD1218  [3]
 LDCM0340  AC75 PaTu 8988t C577(0.91); C1070(1.33); C140(0.90); C182(1.12)  LDD1219  [3]
 LDCM0341  AC76 PaTu 8988t C577(0.95); C1070(1.16); C140(0.86); C182(0.89)  LDD1220  [3]
 LDCM0342  AC77 PaTu 8988t C577(0.70); C1070(1.26); C140(0.79); C182(0.97)  LDD1221  [3]
 LDCM0343  AC78 PaTu 8988t C577(0.77); C1070(1.04); C140(0.79); C182(0.88)  LDD1222  [3]
 LDCM0344  AC79 PaTu 8988t C577(0.74); C1070(1.25); C140(1.01); C182(1.11)  LDD1223  [3]
 LDCM0345  AC8 PaTu 8988t C1070(0.94); C1013(0.75); C1016(0.75); C140(0.96)  LDD1224  [3]
 LDCM0346  AC80 PaTu 8988t C577(0.63); C1070(1.21); C140(0.84); C182(0.90)  LDD1225  [3]
 LDCM0347  AC81 PaTu 8988t C577(0.74); C1070(1.14); C140(1.12); C182(0.90)  LDD1226  [3]
 LDCM0348  AC82 PaTu 8988t C577(0.67); C1070(1.21); C140(0.87); C182(0.99)  LDD1227  [3]
 LDCM0349  AC83 PaTu 8988t C577(0.81); C669(0.86); C1013(1.25); C1016(1.25)  LDD1228  [3]
 LDCM0350  AC84 PaTu 8988t C577(0.67); C669(0.68); C1013(1.24); C1016(1.24)  LDD1229  [3]
 LDCM0351  AC85 PaTu 8988t C577(0.78); C669(0.77); C1013(1.27); C1016(1.27)  LDD1230  [3]
 LDCM0352  AC86 PaTu 8988t C577(0.79); C669(0.85); C1013(1.24); C1016(1.24)  LDD1231  [3]
 LDCM0353  AC87 PaTu 8988t C577(0.76); C669(0.89); C1013(1.38); C1016(1.38)  LDD1232  [3]
 LDCM0354  AC88 PaTu 8988t C577(0.88); C669(0.94); C1013(1.17); C1016(1.17)  LDD1233  [3]
 LDCM0355  AC89 PaTu 8988t C577(0.83); C669(0.75); C1013(1.18); C1016(1.18)  LDD1234  [3]
 LDCM0357  AC90 PaTu 8988t C577(0.95); C669(1.03); C1013(1.14); C1016(1.14)  LDD1236  [3]
 LDCM0358  AC91 PaTu 8988t C577(0.80); C669(0.96); C1013(1.30); C1016(1.30)  LDD1237  [3]
 LDCM0359  AC92 PaTu 8988t C577(0.87); C669(0.83); C1013(1.08); C1016(1.08)  LDD1238  [3]
 LDCM0360  AC93 PaTu 8988t C577(0.76); C669(0.90); C1013(1.18); C1016(1.18)  LDD1239  [3]
 LDCM0361  AC94 PaTu 8988t C577(0.75); C669(0.92); C1013(1.21); C1016(1.21)  LDD1240  [3]
 LDCM0362  AC95 PaTu 8988t C577(0.91); C669(0.86); C1013(1.11); C1016(1.11)  LDD1241  [3]
 LDCM0363  AC96 PaTu 8988t C577(0.79); C669(0.80); C1013(1.14); C1016(1.14)  LDD1242  [3]
 LDCM0364  AC97 PaTu 8988t C577(0.92); C669(0.74); C1013(1.24); C1016(1.24)  LDD1243  [3]
 LDCM0365  AC98 PaTu 8988t C1013(0.75); C1016(0.75); C140(1.11); C182(1.11)  LDD1244  [3]
 LDCM0366  AC99 PaTu 8988t C1013(1.10); C1016(1.10); C140(1.11); C182(0.79)  LDD1245  [3]
 LDCM0248  AKOS034007472 PaTu 8988t C1070(1.10); C1013(0.85); C1016(0.85); C140(1.74)  LDD1127  [3]
 LDCM0356  AKOS034007680 PaTu 8988t C1070(1.58); C1013(0.93); C1016(0.93); C140(1.10)  LDD1235  [3]
 LDCM0275  AKOS034007705 PaTu 8988t C1070(1.26); C1013(0.84); C1016(0.84); C140(1.64)  LDD1154  [3]
 LDCM0020  ARS-1620 HCC44 C1067(1.19); C1070(1.19); C140(0.98); C669(0.86)  LDD0078  [3]
 LDCM0630  CCW28-3 231MFP C140(1.28)  LDD2214  [12]
 LDCM0108  Chloroacetamide HeLa C182(0.00); C577(0.00); C140(0.00); H599(0.00)  LDD0222  [9]
 LDCM0367  CL1 PaTu 8988t C577(0.98); C863(1.02); C669(1.03); C1013(1.09)  LDD1246  [3]
 LDCM0368  CL10 PaTu 8988t C577(1.49); C863(1.24); C669(1.33); C1013(1.15)  LDD1247  [3]
 LDCM0369  CL100 PaTu 8988t C1070(1.11); C669(0.47); C1013(0.88); C1016(0.88)  LDD1248  [3]
 LDCM0370  CL101 PaTu 8988t C1070(1.40); C1013(0.95); C1016(0.95); C140(1.42)  LDD1249  [3]
 LDCM0371  CL102 PaTu 8988t C1070(1.13); C1013(1.16); C1016(1.16); C140(1.20)  LDD1250  [3]
 LDCM0372  CL103 PaTu 8988t C1070(1.12); C1013(0.87); C1016(0.87); C140(2.35)  LDD1251  [3]
 LDCM0373  CL104 PaTu 8988t C1070(1.17); C1013(1.12); C1016(1.12); C140(1.25)  LDD1252  [3]
 LDCM0374  CL105 PaTu 8988t C1067(1.24); C577(0.78); C863(1.14); C1070(1.23)  LDD1253  [3]
 LDCM0375  CL106 PaTu 8988t C1067(1.19); C577(0.88); C863(1.23); C1070(1.12)  LDD1254  [3]
 LDCM0376  CL107 PaTu 8988t C1067(1.05); C577(0.90); C863(1.17); C1070(1.09)  LDD1255  [3]
 LDCM0377  CL108 PaTu 8988t C1067(1.03); C577(1.05); C863(1.07); C1070(1.07)  LDD1256  [3]
 LDCM0378  CL109 PaTu 8988t C1067(1.18); C577(1.04); C863(1.16); C1070(1.26)  LDD1257  [3]
 LDCM0379  CL11 PaTu 8988t C577(0.95); C863(1.18); C669(1.06); C1013(1.26)  LDD1258  [3]
 LDCM0380  CL110 PaTu 8988t C1067(1.48); C577(0.97); C863(1.38); C1070(1.36)  LDD1259  [3]
 LDCM0381  CL111 PaTu 8988t C1067(1.58); C577(1.34); C863(1.60); C1070(1.55)  LDD1260  [3]
 LDCM0382  CL112 PaTu 8988t C140(1.22); C182(1.03)  LDD1261  [3]
 LDCM0383  CL113 PaTu 8988t C140(1.36); C182(0.90)  LDD1262  [3]
 LDCM0384  CL114 PaTu 8988t C140(2.71); C182(1.08)  LDD1263  [3]
 LDCM0385  CL115 PaTu 8988t C140(1.33); C182(1.17)  LDD1264  [3]
 LDCM0386  CL116 PaTu 8988t C140(1.09); C182(1.22)  LDD1265  [3]
 LDCM0387  CL117 PaTu 8988t C1067(1.14); C863(1.10); C1070(1.14); C669(1.39)  LDD1266  [3]
 LDCM0388  CL118 PaTu 8988t C1067(1.20); C863(1.13); C1070(1.20); C669(1.30)  LDD1267  [3]
 LDCM0389  CL119 PaTu 8988t C1067(1.19); C863(1.30); C1070(1.19); C669(1.33)  LDD1268  [3]
 LDCM0390  CL12 PaTu 8988t C577(1.19); C863(1.25); C669(1.14); C1013(1.20)  LDD1269  [3]
 LDCM0391  CL120 PaTu 8988t C1067(1.25); C863(1.36); C1070(1.25); C669(1.30)  LDD1270  [3]
 LDCM0392  CL121 PaTu 8988t C577(0.88); C669(1.23); C1013(1.07); C1016(1.07)  LDD1271  [3]
 LDCM0393  CL122 PaTu 8988t C577(1.11); C669(1.90); C1013(0.88); C1016(0.88)  LDD1272  [3]
 LDCM0394  CL123 PaTu 8988t C577(1.09); C669(1.59); C1013(0.95); C1016(0.95)  LDD1273  [3]
 LDCM0395  CL124 PaTu 8988t C577(1.11); C669(1.64); C1013(0.96); C1016(0.96)  LDD1274  [3]
 LDCM0396  CL125 PaTu 8988t C669(0.93); C1013(0.89); C1016(0.89); C140(1.04)  LDD1275  [3]
 LDCM0397  CL126 PaTu 8988t C669(1.12); C1013(0.93); C1016(0.93); C140(1.10)  LDD1276  [3]
 LDCM0398  CL127 PaTu 8988t C669(1.15); C1013(0.95); C1016(0.95); C140(0.82)  LDD1277  [3]
 LDCM0399  CL128 PaTu 8988t C669(0.98); C1013(0.98); C1016(0.98); C140(1.17)  LDD1278  [3]
 LDCM0400  CL13 PaTu 8988t C577(1.89); C863(1.18); C669(1.55); C1013(1.34)  LDD1279  [3]
 LDCM0401  CL14 PaTu 8988t C577(2.05); C863(1.44); C669(1.64); C1013(1.40)  LDD1280  [3]
 LDCM0402  CL15 PaTu 8988t C577(1.27); C863(1.39); C669(1.36); C1013(1.15)  LDD1281  [3]
 LDCM0403  CL16 PaTu 8988t C577(1.14); C863(1.25); C1013(0.41); C1016(0.41)  LDD1282  [3]
 LDCM0404  CL17 PaTu 8988t C577(1.02); C863(1.11); C1013(0.73); C1016(0.73)  LDD1283  [3]
 LDCM0405  CL18 PaTu 8988t C577(0.95); C863(1.41); C1013(0.80); C1016(0.80)  LDD1284  [3]
 LDCM0406  CL19 PaTu 8988t C577(0.93); C863(1.31); C1013(0.85); C1016(0.85)  LDD1285  [3]
 LDCM0407  CL2 PaTu 8988t C577(1.06); C863(1.11); C669(0.99); C1013(1.18)  LDD1286  [3]
 LDCM0408  CL20 PaTu 8988t C577(0.90); C863(1.71); C1013(0.81); C1016(0.81)  LDD1287  [3]
 LDCM0409  CL21 PaTu 8988t C577(1.27); C863(1.68); C1013(0.76); C1016(0.76)  LDD1288  [3]
 LDCM0410  CL22 PaTu 8988t C577(1.20); C863(1.35); C1013(0.85); C1016(0.85)  LDD1289  [3]
 LDCM0411  CL23 PaTu 8988t C577(1.18); C863(1.67); C1013(0.89); C1016(0.89)  LDD1290  [3]
 LDCM0412  CL24 PaTu 8988t C577(1.07); C863(1.28); C1013(0.82); C1016(0.82)  LDD1291  [3]
 LDCM0413  CL25 PaTu 8988t C577(1.27); C863(1.26); C1013(0.74); C1016(0.74)  LDD1292  [3]
 LDCM0414  CL26 PaTu 8988t C577(1.22); C863(1.48); C1013(0.90); C1016(0.90)  LDD1293  [3]
 LDCM0415  CL27 PaTu 8988t C577(1.37); C863(1.45); C1013(0.85); C1016(0.85)  LDD1294  [3]
 LDCM0416  CL28 PaTu 8988t C577(1.06); C863(1.60); C1013(0.89); C1016(0.89)  LDD1295  [3]
 LDCM0417  CL29 PaTu 8988t C577(1.08); C863(1.64); C1013(0.76); C1016(0.76)  LDD1296  [3]
 LDCM0418  CL3 PaTu 8988t C577(1.17); C863(1.51); C669(1.26); C1013(0.89)  LDD1297  [3]
 LDCM0419  CL30 PaTu 8988t C577(1.18); C863(1.51); C1013(0.83); C1016(0.83)  LDD1298  [3]
 LDCM0420  CL31 PaTu 8988t C863(1.18); C669(0.96); C1013(0.97); C1016(0.97)  LDD1299  [3]
 LDCM0421  CL32 PaTu 8988t C863(1.53); C669(0.85); C1013(1.13); C1016(1.13)  LDD1300  [3]
 LDCM0422  CL33 PaTu 8988t C863(1.53); C669(1.14); C1013(1.00); C1016(1.00)  LDD1301  [3]
 LDCM0423  CL34 PaTu 8988t C863(1.66); C669(1.27); C1013(1.07); C1016(1.07)  LDD1302  [3]
 LDCM0424  CL35 PaTu 8988t C669(1.23); C1013(1.10); C1016(1.10); C140(1.75)  LDD1303  [3]
 LDCM0425  CL36 PaTu 8988t C863(1.66); C669(1.06); C1013(0.45); C1016(0.45)  LDD1304  [3]
 LDCM0426  CL37 PaTu 8988t C863(1.95); C669(1.31); C1013(1.09); C1016(1.09)  LDD1305  [3]
 LDCM0428  CL39 PaTu 8988t C863(1.73); C669(1.08); C1013(0.97); C1016(0.97)  LDD1307  [3]
 LDCM0429  CL4 PaTu 8988t C577(1.14); C863(1.00); C669(1.03); C1013(0.89)  LDD1308  [3]
 LDCM0430  CL40 PaTu 8988t C863(1.77); C669(1.04); C1013(1.14); C1016(1.14)  LDD1309  [3]
 LDCM0431  CL41 PaTu 8988t C863(1.90); C669(0.99); C1013(1.00); C1016(1.00)  LDD1310  [3]
 LDCM0432  CL42 PaTu 8988t C863(2.20); C669(1.11); C1013(1.18); C1016(1.18)  LDD1311  [3]
 LDCM0433  CL43 PaTu 8988t C863(3.19); C669(1.31); C1013(1.16); C1016(1.16)  LDD1312  [3]
 LDCM0434  CL44 PaTu 8988t C863(1.98); C669(1.31); C1013(0.95); C1016(0.95)  LDD1313  [3]
 LDCM0435  CL45 PaTu 8988t C863(1.43); C669(1.49); C1013(0.93); C1016(0.93)  LDD1314  [3]
 LDCM0436  CL46 PaTu 8988t C1070(1.13); C1013(0.91); C1016(0.91); C140(1.21)  LDD1315  [3]
 LDCM0437  CL47 PaTu 8988t C1070(0.90); C1013(0.94); C1016(0.94); C140(1.07)  LDD1316  [3]
 LDCM0438  CL48 PaTu 8988t C1070(1.19); C1013(0.99); C1016(0.99); C140(1.31)  LDD1317  [3]
 LDCM0439  CL49 PaTu 8988t C1070(1.31); C1013(0.87); C1016(0.87); C140(1.20)  LDD1318  [3]
 LDCM0440  CL5 PaTu 8988t C577(1.57); C863(1.74); C669(1.43); C1013(1.34)  LDD1319  [3]
 LDCM0441  CL50 PaTu 8988t C1070(1.48); C1013(1.04); C1016(1.04); C140(1.13)  LDD1320  [3]
 LDCM0442  CL51 PaTu 8988t C1070(1.58); C1013(0.85); C1016(0.85); C140(1.30)  LDD1321  [3]
 LDCM0443  CL52 PaTu 8988t C1070(1.19); C1013(0.95); C1016(0.95); C140(1.08)  LDD1322  [3]
 LDCM0444  CL53 PaTu 8988t C1070(1.33); C1013(0.80); C1016(0.80); C140(1.51)  LDD1323  [3]
 LDCM0445  CL54 PaTu 8988t C1070(1.25); C1013(0.90); C1016(0.90); C140(1.12)  LDD1324  [3]
 LDCM0446  CL55 PaTu 8988t C1070(1.29); C1013(0.98); C1016(0.98); C140(1.02)  LDD1325  [3]
 LDCM0447  CL56 PaTu 8988t C1070(0.14); C1013(0.95); C1016(0.95); C140(0.78)  LDD1326  [3]
 LDCM0448  CL57 PaTu 8988t C1070(2.04); C1013(1.06); C1016(1.06); C140(1.37)  LDD1327  [3]
 LDCM0449  CL58 PaTu 8988t C1070(1.08); C1013(0.94); C1016(0.94); C140(1.19)  LDD1328  [3]
 LDCM0450  CL59 PaTu 8988t C1070(2.29); C1013(0.93); C1016(0.93); C140(2.09)  LDD1329  [3]
 LDCM0451  CL6 PaTu 8988t C577(1.23); C863(1.33); C669(1.44); C1013(1.33)  LDD1330  [3]
 LDCM0452  CL60 PaTu 8988t C1070(1.78); C1013(0.96); C1016(0.96); C140(1.24)  LDD1331  [3]
 LDCM0453  CL61 PaTu 8988t C1067(1.04); C863(0.99); C1070(1.04); C1013(0.82)  LDD1332  [3]
 LDCM0454  CL62 PaTu 8988t C1067(0.70); C863(1.44); C1070(0.70); C1013(0.81)  LDD1333  [3]
 LDCM0455  CL63 PaTu 8988t C1067(0.85); C863(1.46); C1070(0.85); C1013(0.89)  LDD1334  [3]
 LDCM0456  CL64 PaTu 8988t C1067(0.84); C863(1.61); C1070(0.84); C1013(0.90)  LDD1335  [3]
 LDCM0457  CL65 PaTu 8988t C1067(0.96); C863(1.27); C1070(0.96); C1013(0.94)  LDD1336  [3]
 LDCM0458  CL66 PaTu 8988t C1067(0.85); C863(1.43); C1070(0.85); C1013(1.09)  LDD1337  [3]
 LDCM0459  CL67 PaTu 8988t C1067(0.91); C863(1.42); C1070(0.91); C1013(1.15)  LDD1338  [3]
 LDCM0460  CL68 PaTu 8988t C1067(1.20); C863(1.37); C1070(1.20); C1013(0.94)  LDD1339  [3]
 LDCM0461  CL69 PaTu 8988t C1067(1.57); C863(1.77); C1070(1.57); C1013(1.00)  LDD1340  [3]
 LDCM0462  CL7 PaTu 8988t C577(1.68); C863(1.67); C669(1.50); C1013(1.33)  LDD1341  [3]
 LDCM0463  CL70 PaTu 8988t C1067(1.08); C863(1.51); C1070(1.08); C1013(1.03)  LDD1342  [3]
 LDCM0464  CL71 PaTu 8988t C1067(1.01); C863(1.07); C1070(1.01); C1013(0.88)  LDD1343  [3]
 LDCM0465  CL72 PaTu 8988t C1067(0.91); C863(1.37); C1070(0.91); C1013(0.91)  LDD1344  [3]
 LDCM0466  CL73 PaTu 8988t C1067(1.23); C863(1.82); C1070(1.23); C1013(0.78)  LDD1345  [3]
 LDCM0467  CL74 PaTu 8988t C1067(1.20); C863(1.18); C1070(1.20); C1013(0.81)  LDD1346  [3]
 LDCM0469  CL76 PaTu 8988t C863(1.10); C1013(0.90); C1016(0.90); C140(1.55)  LDD1348  [3]
 LDCM0470  CL77 PaTu 8988t C863(1.09); C1013(0.92); C1016(0.92); C140(1.41)  LDD1349  [3]
 LDCM0471  CL78 PaTu 8988t C863(1.42); C1013(1.08); C1016(1.08); C140(1.32)  LDD1350  [3]
 LDCM0472  CL79 PaTu 8988t C863(1.37); C1013(1.40); C1016(1.40); C140(1.28)  LDD1351  [3]
 LDCM0473  CL8 PaTu 8988t C577(1.40); C863(1.55); C669(1.39); C1013(0.94)  LDD1352  [3]
 LDCM0474  CL80 PaTu 8988t C863(1.21); C1013(0.87); C1016(0.87); C140(1.55)  LDD1353  [3]
 LDCM0475  CL81 PaTu 8988t C863(1.40); C1013(1.11); C1016(1.11); C140(1.52)  LDD1354  [3]
 LDCM0476  CL82 PaTu 8988t C863(1.48); C1013(0.97); C1016(0.97); C140(1.50)  LDD1355  [3]
 LDCM0477  CL83 PaTu 8988t C863(1.56); C1013(0.93); C1016(0.93); C140(2.48)  LDD1356  [3]
 LDCM0478  CL84 PaTu 8988t C863(1.27); C1013(1.08); C1016(1.08); C140(2.32)  LDD1357  [3]
 LDCM0479  CL85 PaTu 8988t C863(1.12); C1013(1.20); C1016(1.20); C140(1.51)  LDD1358  [3]
 LDCM0480  CL86 PaTu 8988t C863(1.33); C1013(0.88); C1016(0.88); C140(1.98)  LDD1359  [3]
 LDCM0481  CL87 PaTu 8988t C863(1.35); C1013(0.85); C1016(0.85); C140(1.91)  LDD1360  [3]
 LDCM0482  CL88 PaTu 8988t C863(1.56); C1013(1.15); C1016(1.15); C140(1.64)  LDD1361  [3]
 LDCM0483  CL89 PaTu 8988t C863(1.12); C1013(1.02); C1016(1.02); C140(2.07)  LDD1362  [3]
 LDCM0484  CL9 PaTu 8988t C577(1.48); C863(1.11); C669(1.18); C1013(1.27)  LDD1363  [3]
 LDCM0485  CL90 PaTu 8988t C863(1.36); C1013(0.92); C1016(0.92); C140(2.13)  LDD1364  [3]
 LDCM0486  CL91 PaTu 8988t C1070(1.15); C669(0.40); C1013(0.99); C1016(0.99)  LDD1365  [3]
 LDCM0487  CL92 PaTu 8988t C1070(1.01); C669(0.41); C1013(0.99); C1016(0.99)  LDD1366  [3]
 LDCM0488  CL93 PaTu 8988t C1070(1.01); C669(0.42); C1013(1.03); C1016(1.03)  LDD1367  [3]
 LDCM0489  CL94 PaTu 8988t C1070(1.02); C669(0.47); C1013(0.95); C1016(0.95)  LDD1368  [3]
 LDCM0490  CL95 PaTu 8988t C1070(1.06); C669(0.53); C1013(0.92); C1016(0.92)  LDD1369  [3]
 LDCM0491  CL96 PaTu 8988t C1070(0.89); C669(0.37); C1013(0.86); C1016(0.86)  LDD1370  [3]
 LDCM0492  CL97 PaTu 8988t C1070(1.08); C669(0.55); C1013(1.10); C1016(1.10)  LDD1371  [3]
 LDCM0493  CL98 PaTu 8988t C1070(1.26); C669(0.63); C1013(0.84); C1016(0.84)  LDD1372  [3]
 LDCM0494  CL99 PaTu 8988t C1070(1.26); C669(0.46); C1013(1.00); C1016(1.00)  LDD1373  [3]
 LDCM0495  E2913 HEK-293T C577(1.09); C669(0.95)  LDD1698  [13]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C577(1.04)  LDD1702  [14]
 LDCM0572  Fragment10 MDA-MB-231 C140(1.79)  LDD1389  [15]
 LDCM0573  Fragment11 MDA-MB-231 C140(3.21)  LDD1391  [15]
 LDCM0574  Fragment12 MDA-MB-231 C140(1.43)  LDD1393  [15]
 LDCM0575  Fragment13 MDA-MB-231 C140(1.13)  LDD1469  [15]
 LDCM0576  Fragment14 MDA-MB-231 C140(4.22)  LDD1397  [15]
 LDCM0579  Fragment20 MDA-MB-231 C140(2.29)  LDD1402  [15]
 LDCM0580  Fragment21 MDA-MB-231 C140(0.98)  LDD1404  [15]
 LDCM0582  Fragment23 MDA-MB-231 C140(2.36)  LDD1408  [15]
 LDCM0584  Fragment25 MDA-MB-231 C140(0.68)  LDD1411  [15]
 LDCM0578  Fragment27 MDA-MB-231 C140(1.44)  LDD1401  [15]
 LDCM0586  Fragment28 MDA-MB-231 C140(1.13)  LDD1415  [15]
 LDCM0587  Fragment29 MDA-MB-231 C140(1.08)  LDD1417  [15]
 LDCM0588  Fragment30 MDA-MB-231 C140(0.83)  LDD1419  [15]
 LDCM0589  Fragment31 MDA-MB-231 C140(5.93)  LDD1421  [15]
 LDCM0590  Fragment32 MDA-MB-231 C140(3.11)  LDD1423  [15]
 LDCM0468  Fragment33 PaTu 8988t C1067(0.89); C863(1.33); C1070(0.89); C1013(1.13)  LDD1347  [3]
 LDCM0594  Fragment36 MDA-MB-231 C140(1.42)  LDD1431  [15]
 LDCM0596  Fragment38 MDA-MB-231 C140(1.53)  LDD1433  [15]
 LDCM0566  Fragment4 MDA-MB-231 C140(1.40)  LDD1378  [15]
 LDCM0598  Fragment40 MDA-MB-231 C140(0.94)  LDD1436  [15]
 LDCM0599  Fragment41 MDA-MB-231 C140(0.54)  LDD1481  [15]
 LDCM0601  Fragment43 MDA-MB-231 C140(5.32)  LDD1441  [15]
 LDCM0603  Fragment45 MDA-MB-231 C140(20.00)  LDD1444  [15]
 LDCM0604  Fragment46 MDA-MB-231 C140(1.03)  LDD1445  [15]
 LDCM0605  Fragment47 MDA-MB-231 C140(1.23)  LDD1446  [15]
 LDCM0606  Fragment48 MDA-MB-231 C140(1.46)  LDD1447  [15]
 LDCM0608  Fragment50 MDA-MB-231 C140(2.20)  LDD1449  [15]
 LDCM0427  Fragment51 PaTu 8988t C863(1.31); C669(1.43); C1013(0.96); C1016(0.96)  LDD1306  [3]
 LDCM0610  Fragment52 MDA-MB-231 C140(1.39)  LDD1452  [15]
 LDCM0614  Fragment56 MDA-MB-231 C140(1.41)  LDD1458  [15]
 LDCM0568  Fragment6 MDA-MB-231 C140(1.21)  LDD1382  [15]
 LDCM0570  Fragment8 MDA-MB-231 C140(20.00)  LDD1462  [15]
 LDCM0571  Fragment9 MDA-MB-231 C140(1.46)  LDD1387  [15]
 LDCM0022  KB02 MDA-MB-231 C140(20.00)  LDD1374  [15]
 LDCM0023  KB03 MDA-MB-231 C140(2.24)  LDD1376  [15]
 LDCM0024  KB05 HMCB C718(2.14)  LDD3312  [16]
 LDCM0109  NEM HeLa H599(0.00); H906(0.00); H342(0.00)  LDD0223  [9]

References

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Mass spectrometry data entry: PXD028270
2 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
5 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
6 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
7 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
8 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
9 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
10 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010
11 Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. Nat Chem Biol. 2020 Feb;16(2):150-159. doi: 10.1038/s41589-019-0404-5. Epub 2019 Nov 25.
12 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
13 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
14 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
15 Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.
16 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840