Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0587
Competitor Name
Fragment29
Synonyms
900641-12-5; 2-Chloro-1-(4-(2-morpholino-2-oxoethyl)piperazin-1-yl)ethan-1-one; SCHEMBL22196916; DTXSID101177976; 2-[4-(2-Chloroacetyl)-1-piperazinyl]-1-(4-morpholinyl)ethanone
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 289.76
Lipid-water partition coefficient (xlogp) -0.7
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C12H20ClN3O3
IUPAC Name
2-[4-(2-chloroacetyl)piperazin-1-yl]-1-morpholin-4-ylethanone
Canonical SMILES
C1CN(CCN1CC(=O)N2CCOCC2)C(=O)CCl
InChI
InChI=1S/C12H20ClN3O3/c13-9-11(17)15-3-1-14(2-4-15)10-12(18)16-5-7-19-8-6-16/h1-10H2
InChIKey
YGHXRSQVSHCCID-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
IA-alkyne
 Probe Info  		100 uM Human breast adenocarcinoma cell lysate (MDA-MB-231) [1]

Target(s) List of this Competitor

141 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 1.13; 1.28  LDD1417 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 1.03  LDD1417 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 1.15  LDD1417 
3-ketoacyl-CoA thiolase, mitochondrial (ACAA2) LDTP03998 0.94  LDD1417 
3-ketoacyl-CoA thiolase, peroxisomal (ACAA1) LDTP02329 1.05  LDD1417 
5'-nucleotidase domain-containing protein 1 (NT5DC1) LDTP17247 1.21  LDD1417 
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (PFKFB2) LDTP01055 0.90  LDD1476 
6-phosphogluconolactonase (PGLS) LDTP14535 1.61  LDD1417 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 1.13  LDD1417 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 1.32; 1.31; 1.30 ...  LDD1417 
Adenosine 5'-monophosphoramidase HINT1 (HINT1) LDTP04306 0.59  LDD1417 
Adenosine kinase (ADK) LDTP04689 1.01  LDD1417 
ADP-ribose glycohydrolase MACROD1 (MACROD1) LDTP11059 1.54  LDD1476 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 1.07  LDD1476 
Aldehyde dehydrogenase, mitochondrial (ALDH2) LDTP02074 10.48  LDD1476 
Aldo-keto reductase family 1 member B1 (AKR1B1) LDTP02765 1.16  LDD1417 
All trans-polyprenyl-diphosphate synthase PDSS2 (PDSS2) LDTP08401 1.14  LDD1476 
Amidophosphoribosyltransferase (PPAT) LDTP05480 1.58  LDD1476 
AMP deaminase 2 (AMPD2) LDTP05289 1.29  LDD1417 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 1.33  LDD1417 
Aspartyl aminopeptidase (DNPEP) LDTP13527 1.32  LDD1476 
ATP-dependent 6-phosphofructokinase, platelet type (PFKP) LDTP05314 1.23; 0.99  LDD1417 
ATPase WRNIP1 (WRNIP1) LDTP10801 1.16  LDD1417 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 1.07  LDD1418 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 1.25  LDD1417 
Calpain-2 catalytic subunit (CAPN2) LDTP02911 0.86  LDD1417 
Caspase-8 (CASP8) LDTP06211 1.60  LDD1476 
Cathepsin B (CTSB) LDTP02223 1.66; 2.59  LDD1417 
Cathepsin D (CTSD) LDTP02198 1.42  LDD1417 
Cathepsin Z (CTSZ) LDTP13147 0.96; 2.52  LDD1417 
Cell cycle checkpoint control protein RAD9A (RAD9A) LDTP10929 1.24  LDD1417 
Cleavage and polyadenylation specificity factor subunit 3 (CPSF3) LDTP13449 1.82  LDD1417 
Cyclin-dependent kinase 19 (CDK19) LDTP11340 1.04  LDD1417 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 1.49  LDD1417 
Cyclin-dependent kinase inhibitor 3 (CDKN3) LDTP06603 1.68  LDD1476 
Cytidine deaminase (CDA) LDTP03642 1.21  LDD1417 
D-3-phosphoglycerate dehydrogenase (PHGDH) LDTP00701 0.84  LDD1418 
Deoxycytidine kinase (DCK) LDTP03400 1.44; 1.55  LDD1417 
Desumoylating isopeptidase 1 (DESI1) LDTP07407 1.04  LDD1476 
DNA dC->dU-editing enzyme APOBEC-3C (APOBEC3C) LDTP12539 13.34  LDD1476 
DNA repair protein RAD50 (RAD50) LDTP09912 1.24  LDD1417 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 1.29  LDD1476 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 1.12  LDD1417 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 1.13  LDD1417 
Double-stranded RNA-specific adenosine deaminase (ADAR) LDTP04690 1.85  LDD1417 
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) LDTP04103 1.19  LDD1417 
Dual specificity mitogen-activated protein kinase kinase 4 (MAP2K4) LDTP04077 1.04  LDD1417 
Dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7) LDTP00414 0.97  LDD1476 
Dynamin-1-like protein (DNM1L) LDTP00273 1.18  LDD1417 
Dynamin-2 (DNM2) LDTP04374 1.27  LDD1417 
Elongation factor 2 (EEF2) LDTP02672 1.25; 1.19  LDD1417 
Elongation factor G, mitochondrial (GFM1) LDTP10774 1.15  LDD1476 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 1.41  LDD1417 
Enoyl-CoA delta isomerase 2 (ECI2) LDTP01245 1.17  LDD1417 
ERO1-like protein alpha (ERO1A) LDTP10386 1.10; 0.82; 1.32  LDD1417 
Ethylmalonyl-CoA decarboxylase (ECHDC1) LDTP16095 1.07  LDD1417 
Eukaryotic translation initiation factor 3 subunit F (EIF3F) LDTP00246 0.81  LDD1418 
FAD synthase (FLAD1) LDTP09200 3.38  LDD1476 
Fructose-2,6-bisphosphatase TIGAR (TIGAR) LDTP12405 1.29; 0.94  LDD1476 
General transcription and DNA repair factor IIH helicase subunit XPB (ERCC3) LDTP03000 0.77  LDD1417 
Glutaredoxin-1 (GLRX) LDTP03786 1.02  LDD1417 
Glutaredoxin-related protein 5, mitochondrial (GLRX5) LDTP08181 0.84  LDD1417 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 1.65  LDD1417 
Glutathione S-transferase P (GSTP1) LDTP02333 1.02  LDD1417 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 1.00  LDD1417 
Glycerol-3-phosphate phosphatase (PGP) LDTP00089 1.49  LDD1417 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 1.58  LDD1417 
GMP reductase 2 (GMPR2) LDTP13080 1.08  LDD1417 
Haloacid dehalogenase-like hydrolase domain-containing 5 (HDHD5) LDTP18330 1.47  LDD1476 
Helicase ARIP4 (RAD54L2) LDTP14036 1.90  LDD1417 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 1.04  LDD1476 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 1.03; 1.06  LDD1417 
Integrin-linked protein kinase (ILK) LDTP05859 1.09  LDD1417 
Isoamyl acetate-hydrolyzing esterase 1 homolog (IAH1) LDTP17082 1.29  LDD1417 
Isochorismatase domain-containing protein 2 (ISOC2) LDTP18123 1.11  LDD1476 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 0.83  LDD1417 
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 0.99  LDD1417 
Ketosamine-3-kinase (FN3KRP) LDTP16025 2.32  LDD1417 
Lysine-specific demethylase 4B (KDM4B) LDTP01470 1.16  LDD1417 
Lysine-specific demethylase RSBN1L (RSBN1L) LDTP17384 1.38  LDD1476 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 2.13  LDD1476 
Mannose-1-phosphate guanyltransferase alpha (GMPPA) LDTP10418 0.91  LDD1417 
Medium-chain acyl-CoA ligase ACSF2, mitochondrial (ACSF2) LDTP10177 1.42  LDD1417 
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial (ALDH6A1) LDTP05346 1.17  LDD1476 
Mitogen-activated protein kinase 9 (MAPK9) LDTP04076 0.85  LDD1417 
Mitogen-activated protein kinase kinase kinase 20 (MAP3K20) LDTP12837 1.17  LDD1417 
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) LDTP07651 1.11  LDD1417 
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) LDTP01005 1.66  LDD1417 
Multifunctional protein CAD (CAD) LDTP03401 1.77  LDD1476 
Myotubularin-related protein 1 (MTMR1) LDTP05943 1.45  LDD1476 
Myotubularin-related protein 12 (MTMR12) LDTP11617 4.61  LDD1476 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 1.54; 1.08  LDD1417 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 1.31  LDD1417 
Nucleoside diphosphate kinase 3 (NME3) LDTP05795 1.50  LDD1476 
Omega-amidase NIT2 (NIT2) LDTP12428 4.83  LDD1418 
Parkinson disease protein 7 (PARK7) LDTP10878 0.92  LDD1417 
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (NGLY1) LDTP10429 3.03  LDD1476 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) LDTP05912 1.05  LDD1417 
Peroxiredoxin-4 (PRDX4) LDTP05773 2.04  LDD1417 
Peroxiredoxin-5, mitochondrial (PRDX5) LDTP03512 0.95; 0.91  LDD1417 
Persulfide dioxygenase ETHE1, mitochondrial (ETHE1) LDTP01633 1.17  LDD1417 
Pre-rRNA-processing protein TSR1 homolog (TSR1) LDTP14888 1.01  LDD1417 
Probable ribonuclease ZC3H12D (ZC3H12D) LDTP00042 1.33  LDD1476 
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1) LDTP05373 1.64  LDD1417 
Prostaglandin E synthase 3 (PTGES3) LDTP06338 1.08  LDD1417 
Protein arginine N-methyltransferase 1 (PRMT1) LDTP10997 0.96  LDD1417 
Protein disulfide-isomerase (P4HB) LDTP02188 0.84  LDD1417 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 0.89  LDD1417 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 1.06; 0.89  LDD1417 
Protein disulfide-isomerase A6 (PDIA6) LDTP06314 1.04  LDD1417 
Protein phosphatase methylesterase 1 (PPME1) LDTP14092 1.16  LDD1476 
Protein PML (PML) LDTP03496 1.14  LDD1417 
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT1) LDTP03152 1.43  LDD1418 
Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 (ALG13) LDTP12313 1.98  LDD1476 
Putative transferase CAF17, mitochondrial (IBA57) LDTP07110 2.42  LDD1417 
Pyruvate carboxylase, mitochondrial (PC) LDTP02576 0.95  LDD1417 
Pyruvate kinase PKM (PKM) LDTP02733 1.23  LDD1417 
Ras-related GTP-binding protein C (RRAGC) LDTP12166 1.32  LDD1417 
Ribonuclease H2 subunit C (RNASEH2C) LDTP09446 1.25  LDD1417 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 1.31  LDD1476 
Serine/threonine-protein kinase A-Raf (ARAF) LDTP02493 1.23  LDD1476 
Serine/threonine-protein phosphatase CPPED1 (CPPED1) LDTP11107 1.34  LDD1417 
Small ribosomal subunit protein uS3 (RPS3) LDTP03223 1.18  LDD1417 
Succinate-semialdehyde dehydrogenase, mitochondrial (ALDH5A1) LDTP04438 1.00  LDD1476 
Thioredoxin (TXN) LDTP02502 1.27  LDD1417 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 0.89; 0.85  LDD1417 
Thioredoxin, mitochondrial (TXN2) LDTP10973 1.56  LDD1476 
Thymidine kinase, cytosolic (TK1) LDTP02022 1.54  LDD1417 
Thymidylate kinase (DTYMK) LDTP03258 1.61  LDD1476 
Thymidylate synthase (TYMS) LDTP02055 2.53  LDD1476 
Transmembrane protease serine 12 (TMPRSS12) LDTP15306 0.82  LDD1417 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 1.32; 1.33; 1.13  LDD1417 
Tubulin alpha-4A chain (TUBA4A) LDTP05075 1.48; 1.22; 1.14  LDD1417 
Tudor-interacting repair regulator protein (NUDT16L1) LDTP11111 1.73  LDD1476 
Ubiquitin carboxyl-terminal hydrolase 7 (USP7) LDTP09962 1.04  LDD1476 
Ubiquitin-conjugating enzyme E2 L3 (UBE2L3) LDTP05070 0.90  LDD1417 
Ubiquitin/ISG15-conjugating enzyme E2 L6 (UBE2L6) LDTP00481 2.41  LDD1476 
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (OGT) LDTP00601 1.49  LDD1417 
Uridine phosphorylase 1 (UPP1) LDTP06643 1.21  LDD1417 
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (PDK1) LDTP06320 1.82  LDD1476 
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP1) LDTP12960 1.35  LDD1417 
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⏷ Show the Full List of 141 Enzyme
20 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Apoptotic chromatin condensation inducer in the nucleus (ACIN1) LDTP13490 1.45  LDD1417 
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 1.25  LDD1417 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 1.03  LDD1417 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 1.04  LDD1417 
Exportin-1 (XPO1) LDTP00501 1.30; 1.02  LDD1417 
Exportin-2 (CSE1L) LDTP04662 0.90  LDD1417 
Gasdermin-D (GSDMD) LDTP04801 0.84  LDD1418 
Importin-7 (IPO7) LDTP01574 1.12  LDD1417 
Nuclear cap-binding protein subunit 1 (NCBP1) LDTP05591 1.09  LDD1476 
Nuclear pore complex protein Nup214 (NUP214) LDTP03777 1.20  LDD1417 
Nuclear pore complex protein Nup93 (NUP93) LDTP08769 0.71  LDD1418 
Nucleoporin NUP35 (NUP35) LDTP09204 1.17  LDD1417 
Protein SEC13 homolog (SEC13) LDTP04707 1.05  LDD1417 
Signal recognition particle 9 kDa protein (SRP9) LDTP04259 1.00  LDD1417 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 1.27  LDD1417 
Sorting nexin-6 (SNX6) LDTP13661 1.18  LDD1417 
Thioredoxin domain-containing protein 17 (TXNDC17) LDTP11103 17.52  LDD1417 
Thioredoxin-interacting protein (TXNIP) LDTP11873 1.20  LDD1417 
Tumor necrosis factor alpha-induced protein 2 (TNFAIP2) LDTP14808 1.52  LDD1417 
Unconventional myosin-Ic (MYO1C) LDTP00196 1.11  LDD1417 
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⏷ Show the Full List of 20 Transporter and channel
10 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
CDKN2A-interacting protein (CDKN2AIP) LDTP12792 1.63  LDD1417 
Chromatin accessibility complex protein 1 (CHRAC1) LDTP12507 0.60  LDD1417 
eIF5-mimic protein 2 (BZW1) LDTP07940 1.23  LDD1417 
Interferon regulatory factor 8 (IRF8) LDTP05362 1.35  LDD1476 
Mothers against decapentaplegic homolog 2 (SMAD2) LDTP06475 1.32  LDD1476 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 1.23  LDD1417 
Recombining binding protein suppressor of hairless (RBPJ) LDTP05485 1.20  LDD1417 
Signal transducer and activator of transcription 1-alpha/beta (STAT1) LDTP03969 3.83  LDD1476 
SWI/SNF complex subunit SMARCC2 (SMARCC2) LDTP09311 1.01  LDD1417 
Zinc finger protein 217 (ZNF217) LDTP01191 0.92  LDD1417 
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⏷ Show the Full List of 10 Transcription factor
132 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Actin-related protein 3 (ACTR3) LDTP04902 0.80  LDD1417 
Acyl-CoA-binding domain-containing protein 6 (ACBD6) LDTP15861 2.54  LDD1476 
AH receptor-interacting protein (AIP) LDTP00202 1.32  LDD1418 
Alpha-actinin-1 (ACTN1) LDTP02631 1.27  LDD1417 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 1.23  LDD1417 
Anillin (ANLN) LDTP12443 1.40  LDD1417 
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1) LDTP10657 1.07  LDD1476 
Ashwin (C2orf49) LDTP15896 1.83  LDD1476 
Ataxin-7-like protein 3B (ATXN7L3B) LDTP15730 1.22  LDD1417 
Biogenesis of lysosome-related organelles complex 1 subunit 3 (BLOC1S3) LDTP07624 1.60  LDD1476 
BRCA1-associated ATM activator 1 (BRAT1) LDTP07598 4.57  LDD1476 
BRISC and BRCA1-A complex member 1 (BABAM1) LDTP12737 1.21  LDD1417 
Calponin-2 (CNN2) LDTP10864 1.72; 1.59  LDD1417 
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) LDTP02511 1.08  LDD1417 
Cleavage stimulation factor subunit 2 (CSTF2) LDTP03665 1.20  LDD1417 
Cofilin-1 (CFL1) LDTP03244 0.84  LDD1417 
Condensin complex subunit 1 (NCAPD2) LDTP06281 1.02  LDD1417 
Condensin complex subunit 2 (NCAPH) LDTP06268 1.35  LDD1417 
Conserved oligomeric Golgi complex subunit 1 (COG1) LDTP09549 1.16  LDD1417 
Copper transport protein ATOX1 (ATOX1) LDTP00229 1.44  LDD1476 
Coronin-1C (CORO1C) LDTP13580 1.39; 1.09  LDD1417 
Crk-like protein (CRKL) LDTP04092 1.69  LDD1418 
Cyclin-H (CCNH) LDTP04487 1.19  LDD1417 
Cysteine and glycine-rich protein 2 (CSRP2) LDTP06542 1.68  LDD1417 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 1.48  LDD1417 
Cytosolic Fe-S cluster assembly factor NUBP2 (NUBP2) LDTP14179 1.12  LDD1476 
Cytosolic iron-sulfur assembly component 2B (CIAO2B) LDTP13979 1.12  LDD1418 
Dedicator of cytokinesis protein 7 (DOCK7) LDTP10613 1.16  LDD1417 
Disks large-associated protein 5 (DLGAP5) LDTP06378 0.71  LDD1417 
DNA mismatch repair protein Msh2 (MSH2) LDTP04028 1.35  LDD1417 
Dynactin subunit 1 (DCTN1) LDTP06082 1.00  LDD1417 
Dynactin subunit 4 (DCTN4) LDTP13402 20.00  LDD1476 
EF-hand domain-containing protein D2 (EFHD2) LDTP15701 0.76  LDD1417 
Elongator complex protein 4 (ELP4) LDTP10252 1.11  LDD1476 
Enhancer of mRNA-decapping protein 3 (EDC3) LDTP10299 1.28  LDD1417 
Eukaryotic translation initiation factor 3 subunit J (EIF3J) LDTP01320 1.46  LDD1417 
Eukaryotic translation initiation factor 3 subunit M (EIF3M) LDTP07947 1.15  LDD1417 
FAS-associated death domain protein (FADD) LDTP05772 1.31  LDD1476 
FH1/FH2 domain-containing protein 1 (FHOD1) LDTP14195 1.72  LDD1417 
Formin-binding protein 1-like (FNBP1L) LDTP07088 1.15  LDD1417 
GrpE protein homolog 1, mitochondrial (GRPEL1) LDTP12144 0.64  LDD1418 
H/ACA ribonucleoprotein complex subunit 2 (NHP2) LDTP12754 0.99  LDD1417 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 1.20  LDD1417 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 1.28; 0.62  LDD1417 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 1.37  LDD1476 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 1.21  LDD1476 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 1.30  LDD1417 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 1.05  LDD1417 
Hippocalcin-like protein 1 (HPCAL1) LDTP03841 1.11  LDD1417 
Hsp70-binding protein 1 (HSPBP1) LDTP12914 1.66  LDD1417 
Integrator complex subunit 13 (INTS13) LDTP12685 0.97  LDD1417 
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) LDTP00463 1.39  LDD1417 
Inverted formin-2 (INF2) LDTP06681 1.14  LDD1417 
KH domain-containing RNA-binding protein QKI (QKI) LDTP10700 1.19  LDD1417 
Kinectin (KTN1) LDTP08238 1.27  LDD1417 
Kinetochore protein NDC80 homolog (NDC80) LDTP00431 1.07  LDD1417 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 1.21; 1.66; 1.27 ...  LDD1417 
LanC-like protein 2 (LANCL2) LDTP12571 1.10  LDD1417 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 1.38; 1.56  LDD1417 
Large ribosomal subunit protein eL30 (RPL30) LDTP05021 1.40  LDD1417 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 1.10  LDD1417 
Large ribosomal subunit protein uL16 (RPL10) LDTP03395 1.48  LDD1417 
Large ribosomal subunit protein uL3 (RPL3) LDTP03865 1.38  LDD1417 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 1.15  LDD1417 
Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) LDTP03997 20.00  LDD1417 
LIM and calponin homology domains-containing protein 1 (LIMCH1) LDTP13705 1.08  LDD1417 
LIM domain only protein 7 (LMO7) LDTP09650 0.96  LDD1476 
Mediator of RNA polymerase II transcription subunit 15 (MED15) LDTP10771 1.09; 1.17  LDD1417 
Mediator of RNA polymerase II transcription subunit 17 (MED17) LDTP12669 0.70  LDD1417 
Mediator of RNA polymerase II transcription subunit 9 (MED9) LDTP16117 0.73  LDD1476 
Mini-chromosome maintenance complex-binding protein (MCMBP) LDTP11197 1.30  LDD1417 
MMS19 nucleotide excision repair protein homolog (MMS19) LDTP10843 0.94  LDD1417 
MOB-like protein phocein (MOB4) LDTP13964 1.25  LDD1417 
Multivesicular body subunit 12A (MVB12A) LDTP10284 1.06  LDD1476 
Neuroblast differentiation-associated protein AHNAK (AHNAK) LDTP05597 1.42  LDD1417 
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (NFU1) LDTP13622 2.04  LDD1476 
Nuclear migration protein nudC (NUDC) LDTP13817 1.34  LDD1417 
Nuclear mitotic apparatus protein 1 (NUMA1) LDTP06244 1.52  LDD1417 
Nucleolar protein 58 (NOP58) LDTP13925 0.86  LDD1417 
NudC domain-containing protein 1 (NUDCD1) LDTP10781 1.27  LDD1417 
Plastin-3 (PLS3) LDTP02692 1.17  LDD1417 
Plectin (PLEC) LDTP06330 1.20; 1.20; 1.08  LDD1417 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 1.17; 1.56  LDD1417 
Programmed cell death 6-interacting protein (PDCD6IP) LDTP09580 0.94  LDD1417 
Proliferation marker protein Ki-67 (MKI67) LDTP04078 1.58  LDD1476 
Proteasome activator complex subunit 1 (PSME1) LDTP05484 1.34  LDD1417 
Proteasome activator complex subunit 4 (PSME4) LDTP06250 1.16  LDD1417 
Protein CBFA2T2 (CBFA2T2) LDTP00768 0.86  LDD1417 
Protein diaphanous homolog 1 (DIAPH1) LDTP01011 1.27  LDD1417 
Protein lin-7 homolog C (LIN7C) LDTP12638 0.92  LDD1417 
Protein misato homolog 1 (MSTO1) LDTP11239 1.02  LDD1417 
Protein PAXX (PAXX) LDTP11235 1.54  LDD1476 
Protein S100-A11 (S100A11) LDTP03620 1.04  LDD1417 
Protein unc-45 homolog A (UNC45A) LDTP11890 1.41  LDD1417 
RAB7A-interacting MON1-CCZ1 complex subunit 1 (RIMOC1) LDTP14351 1.06  LDD1417 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 1.53  LDD1417 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 1.38  LDD1476 
Reticulon-4 (RTN4) LDTP12412 0.95  LDD1417 
Ribosomal protein eL42-like (RPL36AL) LDTP15677 1.37  LDD1418 
Ribosome biogenesis protein BOP1 (BOP1) LDTP06046 1.53  LDD1476 
Serine/threonine-protein phosphatase 4 regulatory subunit 2 (PPP4R2) LDTP12800 1.66  LDD1476 
Sister chromatid cohesion protein PDS5 homolog A (PDS5A) LDTP06684 1.25  LDD1417 
Small ribosomal subunit protein eS27 (RPS27) LDTP03987 1.29  LDD1417 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 1.16  LDD1417 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 1.41  LDD1417 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 1.38; 1.28  LDD1417 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 1.12  LDD1417 
SNW domain-containing protein 1 (SNW1) LDTP05930 1.18  LDD1417 
Stalled ribosome sensor GCN1 (GCN1) LDTP09821 1.22  LDD1417 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 1.33  LDD1417 
Succinate dehydrogenase assembly factor 2, mitochondrial (SDHAF2) LDTP12753 1.86  LDD1476 
T-complex protein 1 subunit alpha (TCP1) LDTP02934 1.10  LDD1417 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 1.03  LDD1417 
T-complex protein 1 subunit eta (CCT7) LDTP10990 1.04  LDD1417 
T-complex protein 1 subunit theta (CCT8) LDTP04390 1.19  LDD1417 
Targeting protein for Xklp2 (TPX2) LDTP13583 1.79  LDD1476 
TBC1 domain family member 23 (TBC1D23) LDTP12651 1.19  LDD1417 
THUMP domain-containing protein 1 (THUMPD1) LDTP12780 1.19  LDD1417 
Trafficking protein particle complex subunit 4 (TRAPPC4) LDTP13837 1.02  LDD1417 
Transcription elongation regulator 1 (TCERG1) LDTP00430 1.23  LDD1417 
Transcription initiation factor IIA subunit 2 (GTF2A2) LDTP04517 1.11  LDD1418 
Treacle protein (TCOF1) LDTP05867 1.33; 1.63  LDD1417 
Tropomodulin-3 (TMOD3) LDTP18494 1.81  LDD1417 
Tubulin beta chain (TUBB) LDTP02205 1.02; 1.28  LDD1417 
U4/U6.U5 tri-snRNP-associated protein 1 (SART1) LDTP00727 1.69  LDD1417 
Uncharacterized protein C3orf38 (C3orf38) LDTP17182 1.27  LDD1476 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 1.29  LDD1417 
Wings apart-like protein homolog (WAPL) LDTP08094 0.74  LDD1476 
WW domain-containing adapter protein with coiled-coil (WAC) LDTP11191 1.03  LDD1417 
Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) LDTP08018 1.63  LDD1476 
Zinc finger protein 346 (ZNF346) LDTP13515 2.35  LDD1476 
ZW10 interactor (ZWINT) LDTP01532 1.05  LDD1417 
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⏷ Show the Full List of 132 Other

Full Information of The Labelling Profiles of This Competitor

IA-alkyne
 Probe Info 
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 100 uM
Quantitative Method Isotope tag
Competitor Name Fragment29
Competitor Concentration 500 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cell lysate (MDA-MB-231)
Interaction Atlas ID  LDD1417  Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 100 uM
Quantitative Method Isotope tag
Competitor Name Fragment29
Competitor Concentration 500 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Lymph node
Disease Model Burkitt lymphoma [ICD-11:2A85]
Model Name Human burkitt lymphoma cell lysate (Ramos)
Interaction Atlas ID  LDD1418  Download The Altas
  
Experiment 3 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 100 uM
Quantitative Method Isotope tag
Competitor Name Fragment29
Competitor Concentration 200 uM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Lymph node
Disease Model Burkitt lymphoma [ICD-11:2A85]
Model Name Human burkitt lymphoma cells (Ramos)
Interaction Atlas ID  LDD1476  Download The Altas

References

1 Proteome-wide covalent ligand discovery in native biological systems. Nature. 2016 Jun 23;534(7608):570-4. doi: 10.1038/nature18002. Epub 2016 Jun 15.