Details of the Target

General Information of Target

Target ID LDTP02677
Target Name Protein disulfide-isomerase A4 (PDIA4)
Gene Name PDIA4
Gene ID 9601
Synonyms
ERP70; ERP72; Protein disulfide-isomerase A4; EC 5.3.4.1; Endoplasmic reticulum resident protein 70; ER protein 70; ERp70; Endoplasmic reticulum resident protein 72; ER protein 72; ERp-72; ERp72
3D Structure
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2D Sequence (FASTA)
Download
3D Structure (PDB)
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Sequence
MRPRKAFLLLLLLGLVQLLAVAGAEGPDEDSSNRENAIEDEEEEEEEDDDEEEDDLEVKE
ENGVLVLNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKI
DATSASVLASRFDVSGYPTIKILKKGQAVDYEGSRTQEEIVAKVREVSQPDWTPPPEVTL
VLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAE
TDLAKRFDVSGYPTLKIFRKGRPYDYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFL
KDGDDVIIIGVFKGESDPAYQQYQDAANNLREDYKFHHTFSTEIAKFLKVSQGQLVVMQP
EKFQSKYEPRSHMMDVQGSTQDSAIKDFVLKYALPLVGHRKVSNDAKRYTRRPLVVVYYS
VDFSFDYRAATQFWRSKVLEVAKDFPEYTFAIADEEDYAGEVKDLGLSESGEDVNAAILD
ESGKKFAMEPEEFDSDTLREFVTAFKKGKLKPVIKSQPVPKNNKGPVKVVVGKTFDSIVM
DPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGF
PTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHATKLSRTKEEL
Target Bioclass
Enzyme
Family
Protein disulfide isomerase family
Subcellular location
Endoplasmic reticulum lumen
Uniprot ID
P13667
Ensemble ID
ENST00000652332.1
HGNC ID
HGNC:30167
ChEMBL ID
CHEMBL4295717

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 32 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		12.55  LDD0402  [1]
A-EBA
 Probe Info  		3.99  LDD0215  [2]
W1
 Probe Info  		61.95  LDD0235  [3]
TH211
 Probe Info  		Y273(11.56)  LDD0260  [4]
TH214
 Probe Info  		Y595(20.00); Y392(12.39)  LDD0258  [4]
YN-1
 Probe Info  		2.26  LDD0444  [5]
ONAyne
 Probe Info  		K211(0.00); K163(0.00); K234(0.00); K637(0.00)  LDD0273  [6]
OPA-S-S-alkyne
 Probe Info  		K145(0.55); K245(1.08); K366(1.22); K582(2.17)  LDD3494  [7]
Probe 1
 Probe Info  		Y101(146.50); Y137(42.38); Y151(48.88); Y252(52.78)  LDD3495  [8]
P12
 Probe Info  		17.33  LDD0202  [9]
AHL-Pu-1
 Probe Info  		C555(3.66)  LDD0170  [10]
HHS-482
 Probe Info  		Y252(1.20); Y273(0.87); Y392(2.55)  LDD0285  [11]
HHS-475
 Probe Info  		Y137(0.77); Y252(0.81); Y392(0.87); Y273(1.02)  LDD0264  [12]
HHS-465
 Probe Info  		Y273(10.00); Y392(8.20)  LDD2237  [13]
DBIA
 Probe Info  		C558(1.09); C91(1.08); C94(1.06)  LDD0078  [14]
5E-2FA
 Probe Info  		N.A.  LDD2235  [15]
AMP probe
 Probe Info  		N.A.  LDD0200  [16]
ATP probe
 Probe Info  		K637(0.00); K576(0.00); K528(0.00); K570(0.00)  LDD0199  [16]
4-Iodoacetamidophenylacetylene
 Probe Info  		C206(0.00); C209(0.00)  LDD0038  [17]
IA-alkyne
 Probe Info  		C206(0.00); C209(0.00)  LDD0036  [17]
Lodoacetamide azide
 Probe Info  		C206(0.00); C209(0.00)  LDD0037  [17]
ATP probe
 Probe Info  		K366(0.00); K524(0.00); K260(0.00); K521(0.00)  LDD0035  [18]
1d-yne
 Probe Info  		N.A.  LDD0356  [19]
Compound 11
 Probe Info  		N.A.  LDD2213  [20]
IPM
 Probe Info  		N.A.  LDD0005  [21]
NHS
 Probe Info  		K349(0.00); K111(0.00); K570(0.00); K485(0.00)  LDD0010  [21]
SF
 Probe Info  		Y252, Y137(0.00); Y392(0.00)  LDD0028  [22]
STPyne
 Probe Info  		K570(0.00); K637(0.00); K571(0.00)  LDD0009  [21]
Phosphinate-6
 Probe Info  		C558(0.00); C555(0.00); C206(0.00)  LDD0018  [23]
1c-yne
 Probe Info  		K485(0.00); K533(0.00); K582(0.00); K349(0.00)  LDD0228  [19]
Acrolein
 Probe Info  		H337(0.00); H634(0.00); H338(0.00); H372(0.00)  LDD0217  [24]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [24]
PAL-AfBPP Probe
Click To Hide/Show 8 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe12
 Probe Info  		12.22  LDD0473  [25]
FFF probe3
 Probe Info  		5.10  LDD0465  [25]
FFF probe4
 Probe Info  		5.36  LDD0466  [25]
FFF probe9
 Probe Info  		12.48  LDD0470  [25]
VE-P
 Probe Info  		N.A.  LDD0396  [26]
CR-1
 Probe Info  		2.60  LDD0429  [27]
Staurosporine capture compound
 Probe Info  		2.44  LDD0083  [28]
STS-1
 Probe Info  		N.A.  LDD0068  [29]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C555(3.66)  LDD0170  [10]
 LDCM0026  4SU-RNA+native RNA DM93 C206(2.97)  LDD0171  [10]
 LDCM0214  AC1 HCT 116 C555(0.91); C91(0.88); C94(0.60); C558(0.89)  LDD0531  [14]
 LDCM0215  AC10 HCT 116 C555(1.36); C91(1.36); C558(1.11)  LDD0532  [14]
 LDCM0216  AC100 HCT 116 C555(0.98); C91(0.98); C558(1.02)  LDD0533  [14]
 LDCM0217  AC101 HCT 116 C555(1.23); C91(1.21); C558(1.01)  LDD0534  [14]
 LDCM0218  AC102 HCT 116 C555(1.07); C91(1.00); C558(0.96)  LDD0535  [14]
 LDCM0219  AC103 HCT 116 C555(1.15); C91(1.15); C558(1.03)  LDD0536  [14]
 LDCM0220  AC104 HCT 116 C555(1.35); C91(1.32); C558(1.14)  LDD0537  [14]
 LDCM0221  AC105 HCT 116 C555(1.12); C91(1.00); C558(0.97)  LDD0538  [14]
 LDCM0222  AC106 HCT 116 C555(0.95); C91(1.12); C558(0.92)  LDD0539  [14]
 LDCM0223  AC107 HCT 116 C555(1.17); C91(1.23); C558(1.06)  LDD0540  [14]
 LDCM0224  AC108 HCT 116 C555(0.87); C91(0.93); C558(0.87)  LDD0541  [14]
 LDCM0225  AC109 HCT 116 C555(0.95); C91(1.03); C558(1.01)  LDD0542  [14]
 LDCM0226  AC11 HCT 116 C555(1.31); C91(1.23); C558(1.00)  LDD0543  [14]
 LDCM0227  AC110 HCT 116 C555(0.97); C91(1.01); C558(0.97)  LDD0544  [14]
 LDCM0228  AC111 HCT 116 C555(0.88); C91(1.24); C558(0.98)  LDD0545  [14]
 LDCM0229  AC112 HCT 116 C555(1.17); C91(2.00); C558(1.44)  LDD0546  [14]
 LDCM0230  AC113 HCT 116 C555(1.08); C91(1.05); C94(1.09); C558(1.10)  LDD0547  [14]
 LDCM0231  AC114 HCT 116 C555(1.26); C91(1.31); C94(1.38); C558(1.47)  LDD0548  [14]
 LDCM0232  AC115 HCT 116 C555(1.37); C91(1.35); C94(1.29); C558(1.65)  LDD0549  [14]
 LDCM0233  AC116 HCT 116 C555(1.30); C91(1.47); C94(1.38); C558(1.38)  LDD0550  [14]
 LDCM0234  AC117 HCT 116 C555(1.15); C91(1.34); C94(1.28); C558(1.34)  LDD0551  [14]
 LDCM0235  AC118 HCT 116 C555(1.09); C91(1.05); C94(1.11); C558(1.22)  LDD0552  [14]
 LDCM0236  AC119 HCT 116 C555(0.99); C91(1.09); C94(0.99); C558(1.06)  LDD0553  [14]
 LDCM0237  AC12 HCT 116 C555(1.03); C91(0.95); C558(0.87)  LDD0554  [14]
 LDCM0238  AC120 HCT 116 C555(1.33); C91(1.31); C94(1.33); C558(1.44)  LDD0555  [14]
 LDCM0239  AC121 HCT 116 C555(0.99); C91(1.32); C94(0.99); C558(1.11)  LDD0556  [14]
 LDCM0240  AC122 HCT 116 C555(0.92); C91(0.97); C94(0.89); C558(1.07)  LDD0557  [14]
 LDCM0241  AC123 HCT 116 C555(1.08); C91(1.13); C94(1.15); C558(1.15)  LDD0558  [14]
 LDCM0242  AC124 HCT 116 C555(1.10); C91(1.51); C94(1.14); C558(1.18)  LDD0559  [14]
 LDCM0243  AC125 HCT 116 C555(1.00); C91(1.09); C94(1.00); C558(1.14)  LDD0560  [14]
 LDCM0244  AC126 HCT 116 C555(1.00); C91(1.08); C94(0.98); C558(1.06)  LDD0561  [14]
 LDCM0245  AC127 HCT 116 C555(0.99); C91(1.17); C94(1.08); C558(1.05)  LDD0562  [14]
 LDCM0246  AC128 HCT 116 C555(0.91); C91(1.06); C558(1.13)  LDD0563  [14]
 LDCM0247  AC129 HCT 116 C555(1.07); C91(1.08); C558(0.89)  LDD0564  [14]
 LDCM0249  AC130 HCT 116 C555(0.86); C91(1.07); C558(1.01)  LDD0566  [14]
 LDCM0250  AC131 HCT 116 C555(1.16); C91(1.07); C558(0.90)  LDD0567  [14]
 LDCM0251  AC132 HCT 116 C555(0.97); C91(1.05); C558(0.88)  LDD0568  [14]
 LDCM0252  AC133 HCT 116 C555(0.96); C91(1.01); C558(0.89)  LDD0569  [14]
 LDCM0253  AC134 HCT 116 C555(1.71); C91(1.15); C558(1.09)  LDD0570  [14]
 LDCM0254  AC135 HCT 116 C555(1.03); C91(1.18); C558(1.18)  LDD0571  [14]
 LDCM0255  AC136 HCT 116 C555(1.10); C91(1.12); C558(1.09)  LDD0572  [14]
 LDCM0256  AC137 HCT 116 C555(1.20); C91(1.05); C558(0.93)  LDD0573  [14]
 LDCM0257  AC138 HCT 116 C555(1.81); C91(1.15); C558(1.08)  LDD0574  [14]
 LDCM0258  AC139 HCT 116 C555(1.24); C91(0.96); C558(0.90)  LDD0575  [14]
 LDCM0259  AC14 HCT 116 C555(1.11); C91(0.94); C558(0.95)  LDD0576  [14]
 LDCM0260  AC140 HCT 116 C555(1.56); C91(1.03); C558(0.95)  LDD0577  [14]
 LDCM0261  AC141 HCT 116 C555(1.80); C91(1.14); C558(0.98)  LDD0578  [14]
 LDCM0262  AC142 HCT 116 C555(1.39); C91(1.09); C558(0.90)  LDD0579  [14]
 LDCM0263  AC143 HCT 116 C555(1.11); C91(1.06); C558(1.01)  LDD0580  [14]
 LDCM0264  AC144 HCT 116 C91(1.23); C555(1.25); C558(1.47)  LDD0581  [14]
 LDCM0265  AC145 HCT 116 C555(1.08); C91(1.12); C558(1.22)  LDD0582  [14]
 LDCM0266  AC146 HCT 116 C555(1.18); C558(1.23); C91(1.47)  LDD0583  [14]
 LDCM0267  AC147 HCT 116 C91(1.17); C558(1.22); C555(1.27)  LDD0584  [14]
 LDCM0268  AC148 HCT 116 C555(1.38); C558(1.47); C91(1.99)  LDD0585  [14]
 LDCM0269  AC149 HCT 116 C555(1.36); C558(1.74); C91(1.79)  LDD0586  [14]
 LDCM0270  AC15 HCT 116 C558(1.14); C555(1.28); C91(1.47)  LDD0587  [14]
 LDCM0271  AC150 HCT 116 C555(1.13); C91(1.22); C558(1.38)  LDD0588  [14]
 LDCM0272  AC151 HCT 116 C555(0.96); C558(1.03); C91(1.04)  LDD0589  [14]
 LDCM0273  AC152 HCT 116 C558(1.03); C555(1.25); C91(1.41)  LDD0590  [14]
 LDCM0274  AC153 HCT 116 C555(1.14); C558(1.51); C91(1.88)  LDD0591  [14]
 LDCM0621  AC154 HCT 116 C555(1.25); C91(1.33); C558(1.15)  LDD2158  [14]
 LDCM0622  AC155 HCT 116 C555(0.98); C91(1.36); C558(1.01)  LDD2159  [14]
 LDCM0623  AC156 HCT 116 C555(0.92); C91(1.07); C558(0.99)  LDD2160  [14]
 LDCM0624  AC157 HCT 116 C555(0.92); C91(1.14); C558(0.99)  LDD2161  [14]
 LDCM0276  AC17 HCT 116 C94(0.78); C91(0.91); C555(1.18); C558(1.44)  LDD0593  [14]
 LDCM0277  AC18 HCT 116 C94(0.88); C91(1.02); C555(1.98); C558(2.72)  LDD0594  [14]
 LDCM0278  AC19 HCT 116 C94(0.83); C91(0.90); C555(1.25); C558(1.87)  LDD0595  [14]
 LDCM0279  AC2 HCT 116 C94(0.64); C558(0.77); C555(0.99); C91(1.01)  LDD0596  [14]
 LDCM0280  AC20 HCT 116 C91(1.04); C94(1.10); C555(1.49); C558(2.66)  LDD0597  [14]
 LDCM0281  AC21 HCT 116 C94(0.81); C91(0.94); C555(1.52); C558(2.59)  LDD0598  [14]
 LDCM0282  AC22 HCT 116 C94(1.05); C91(1.09); C555(1.11); C558(1.20)  LDD0599  [14]
 LDCM0283  AC23 HCT 116 C555(1.04); C94(1.09); C558(1.16); C91(1.19)  LDD0600  [14]
 LDCM0284  AC24 HCT 116 C94(0.83); C555(1.22); C91(1.36); C558(1.37)  LDD0601  [14]
 LDCM0285  AC25 HCT 116 C91(0.88); C94(0.90); C555(1.20)  LDD0602  [14]
 LDCM0286  AC26 HCT 116 C94(0.98); C91(1.04); C555(1.42)  LDD0603  [14]
 LDCM0287  AC27 HCT 116 C94(0.78); C91(1.07); C555(1.19)  LDD0604  [14]
 LDCM0288  AC28 HCT 116 C94(0.87); C91(1.10); C555(1.32)  LDD0605  [14]
 LDCM0289  AC29 HCT 116 C94(0.88); C555(1.36); C91(1.36)  LDD0606  [14]
 LDCM0290  AC3 HCT 116 C94(0.66); C558(0.76); C555(0.80); C91(0.83)  LDD0607  [14]
 LDCM0291  AC30 HCT 116 C94(0.81); C91(1.29); C555(1.39)  LDD0608  [14]
 LDCM0292  AC31 HCT 116 C94(0.87); C91(1.18); C555(1.37)  LDD0609  [14]
 LDCM0293  AC32 HCT 116 C94(0.83); C91(1.46); C555(1.48)  LDD0610  [14]
 LDCM0294  AC33 HCT 116 C94(0.83); C91(1.18); C555(1.51)  LDD0611  [14]
 LDCM0295  AC34 HCT 116 C94(0.81); C91(1.41); C555(1.78)  LDD0612  [14]
 LDCM0296  AC35 HCT 116 C555(1.02); C94(1.17)  LDD0613  [14]
 LDCM0297  AC36 HCT 116 C94(0.99); C555(1.00)  LDD0614  [14]
 LDCM0298  AC37 HCT 116 C555(0.78); C94(0.85)  LDD0615  [14]
 LDCM0299  AC38 HCT 116 C555(0.69); C94(0.77)  LDD0616  [14]
 LDCM0300  AC39 HCT 116 C555(0.87); C94(0.91)  LDD0617  [14]
 LDCM0301  AC4 HCT 116 C94(0.64); C91(0.85); C558(0.90); C555(0.90)  LDD0618  [14]
 LDCM0302  AC40 HCT 116 C555(1.02); C94(1.05)  LDD0619  [14]
 LDCM0303  AC41 HCT 116 C94(0.91); C555(0.92)  LDD0620  [14]
 LDCM0304  AC42 HCT 116 C94(0.93); C555(1.09)  LDD0621  [14]
 LDCM0305  AC43 HCT 116 C555(0.97); C94(0.98)  LDD0622  [14]
 LDCM0306  AC44 HCT 116 C94(0.96); C555(1.03)  LDD0623  [14]
 LDCM0307  AC45 HCT 116 C555(1.06); C94(1.08)  LDD0624  [14]
 LDCM0308  AC46 HCT 116 C558(0.82); C555(0.87); C91(0.92)  LDD0625  [14]
 LDCM0309  AC47 HCT 116 C558(0.72); C91(0.77); C555(0.80)  LDD0626  [14]
 LDCM0310  AC48 HCT 116 C558(0.60); C555(0.65); C91(0.77)  LDD0627  [14]
 LDCM0311  AC49 HCT 116 C558(0.77); C555(1.03); C91(1.37)  LDD0628  [14]
 LDCM0312  AC5 HCT 116 C94(0.60); C558(0.91); C91(0.93); C555(1.07)  LDD0629  [14]
 LDCM0313  AC50 HCT 116 C558(0.76); C555(0.99); C91(1.14)  LDD0630  [14]
 LDCM0314  AC51 HCT 116 C558(0.59); C555(0.77); C91(1.33)  LDD0631  [14]
 LDCM0315  AC52 HCT 116 C555(0.92); C558(0.94); C91(0.99)  LDD0632  [14]
 LDCM0316  AC53 HCT 116 C91(0.99); C555(1.04); C558(1.16)  LDD0633  [14]
 LDCM0317  AC54 HCT 116 C91(0.88); C558(0.98); C555(1.03)  LDD0634  [14]
 LDCM0318  AC55 HCT 116 C558(0.72); C91(0.87); C555(0.89)  LDD0635  [14]
 LDCM0319  AC56 HCT 116 C558(0.45); C555(0.95); C91(0.95)  LDD0636  [14]
 LDCM0320  AC57 HCT 116 C91(0.89); C94(0.97); C555(2.03); C558(2.89)  LDD0637  [14]
 LDCM0321  AC58 HCT 116 C94(0.82); C91(1.10); C555(1.54); C558(1.84)  LDD0638  [14]
 LDCM0322  AC59 HCT 116 C94(0.81); C91(1.15); C558(1.31); C555(1.37)  LDD0639  [14]
 LDCM0323  AC6 HCT 116 C558(1.23); C555(1.29); C91(1.44)  LDD0640  [14]
 LDCM0324  AC60 HCT 116 C94(1.09); C91(1.17); C558(1.29); C555(1.35)  LDD0641  [14]
 LDCM0325  AC61 HCT 116 C91(0.93); C94(1.05); C555(1.54); C558(1.94)  LDD0642  [14]
 LDCM0326  AC62 HCT 116 C94(0.87); C91(0.89); C555(2.05); C558(2.94)  LDD0643  [14]
 LDCM0327  AC63 HCT 116 C94(0.89); C91(1.04); C555(1.85); C558(2.57)  LDD0644  [14]
 LDCM0328  AC64 HCT 116 C94(0.85); C91(0.99); C555(1.83); C558(2.50)  LDD0645  [14]
 LDCM0329  AC65 HCT 116 C94(1.13); C91(1.17); C555(1.50); C558(1.72)  LDD0646  [14]
 LDCM0330  AC66 HCT 116 C94(1.16); C91(1.28); C555(1.45); C558(1.53)  LDD0647  [14]
 LDCM0331  AC67 HCT 116 C94(0.97); C91(1.24); C555(1.86); C558(2.23)  LDD0648  [14]
 LDCM0332  AC68 HCT 116 C91(1.06); C94(1.10); C555(1.23); C558(1.47)  LDD0649  [14]
 LDCM0333  AC69 HCT 116 C91(0.96); C94(0.98); C558(1.23); C555(1.26)  LDD0650  [14]
 LDCM0334  AC7 HCT 116 C558(1.03); C555(1.38); C91(1.59)  LDD0651  [14]
 LDCM0335  AC70 HCT 116 C91(0.89); C558(1.01); C94(1.06); C555(1.14)  LDD0652  [14]
 LDCM0336  AC71 HCT 116 C91(0.86); C94(0.93); C558(0.98); C555(1.11)  LDD0653  [14]
 LDCM0337  AC72 HCT 116 C91(0.92); C94(1.03); C558(1.16); C555(1.22)  LDD0654  [14]
 LDCM0338  AC73 HCT 116 C558(0.79); C94(0.85); C91(0.95); C555(1.39)  LDD0655  [14]
 LDCM0339  AC74 HCT 116 C558(0.80); C91(0.93); C94(0.96); C555(1.60)  LDD0656  [14]
 LDCM0340  AC75 HCT 116 C558(0.90); C91(0.98); C94(1.16); C555(1.58)  LDD0657  [14]
 LDCM0341  AC76 HCT 116 C91(0.86); C94(0.89); C558(0.98); C555(1.07)  LDD0658  [14]
 LDCM0342  AC77 HCT 116 C558(0.95); C94(0.98); C91(1.12); C555(1.26)  LDD0659  [14]
 LDCM0343  AC78 HCT 116 C91(0.89); C94(0.90); C558(0.97); C555(0.99)  LDD0660  [14]
 LDCM0344  AC79 HCT 116 C91(0.96); C555(1.20); C94(1.20); C558(1.21)  LDD0661  [14]
 LDCM0345  AC8 HCT 116 C558(1.04); C555(1.47); C91(2.00)  LDD0662  [14]
 LDCM0346  AC80 HCT 116 C91(0.83); C94(0.91); C558(0.96); C555(1.04)  LDD0663  [14]
 LDCM0347  AC81 HCT 116 C91(1.03); C555(1.16); C94(1.17); C558(1.28)  LDD0664  [14]
 LDCM0348  AC82 HCT 116 C558(0.86); C91(0.97); C94(1.13); C555(1.70)  LDD0665  [14]
 LDCM0349  AC83 HCT 116 C558(1.14); C91(1.59); C555(1.66)  LDD0666  [14]
 LDCM0350  AC84 HCT 116 C558(1.05); C91(1.82); C555(2.06)  LDD0667  [14]
 LDCM0351  AC85 HCT 116 C558(1.10); C91(1.31); C555(1.40)  LDD0668  [14]
 LDCM0352  AC86 HCT 116 C558(1.16); C555(1.33); C91(1.44)  LDD0669  [14]
 LDCM0353  AC87 HCT 116 C558(1.02); C555(1.36); C91(1.36)  LDD0670  [14]
 LDCM0354  AC88 HCT 116 C558(1.03); C555(1.11); C91(1.22)  LDD0671  [14]
 LDCM0355  AC89 HCT 116 C558(0.97); C91(1.37); C555(1.38)  LDD0672  [14]
 LDCM0357  AC90 HCT 116 C558(0.81); C91(0.92); C555(0.96)  LDD0674  [14]
 LDCM0358  AC91 HCT 116 C558(1.13); C555(1.24); C91(1.37)  LDD0675  [14]
 LDCM0359  AC92 HCT 116 C558(0.98); C555(1.06); C91(1.08)  LDD0676  [14]
 LDCM0360  AC93 HCT 116 C558(0.83); C91(1.25); C555(1.34)  LDD0677  [14]
 LDCM0361  AC94 HCT 116 C558(1.12); C555(1.15); C91(1.24)  LDD0678  [14]
 LDCM0362  AC95 HCT 116 C558(0.95); C555(1.34); C91(1.54)  LDD0679  [14]
 LDCM0363  AC96 HCT 116 C558(0.94); C555(1.07); C91(1.14)  LDD0680  [14]
 LDCM0364  AC97 HCT 116 C558(1.06); C555(1.22); C91(1.36)  LDD0681  [14]
 LDCM0365  AC98 HCT 116 C558(0.68); C91(1.08); C555(1.46)  LDD0682  [14]
 LDCM0366  AC99 HCT 116 C558(0.91); C91(0.93); C555(0.99)  LDD0683  [14]
 LDCM0248  AKOS034007472 HCT 116 C555(1.03); C91(0.89); C558(0.90)  LDD0565  [14]
 LDCM0356  AKOS034007680 HCT 116 C558(1.20); C91(1.24); C555(1.38)  LDD0673  [14]
 LDCM0275  AKOS034007705 HCT 116 C558(1.01); C555(1.32); C91(1.46)  LDD0592  [14]
 LDCM0020  ARS-1620 HCC44 C558(1.09); C91(1.08); C94(1.06)  LDD0078  [14]
 LDCM0088  C45 HEK-293T 17.33  LDD0202  [9]
 LDCM0630  CCW28-3 231MFP C206(1.55); C209(1.40); C555(1.28)  LDD2214  [30]
 LDCM0108  Chloroacetamide HeLa H337(0.00); H634(0.00); H372(0.00); H626(0.00)  LDD0222  [24]
 LDCM0367  CL1 HCT 116 C558(2.09); C555(3.05); C91(3.16)  LDD0684  [14]
 LDCM0368  CL10 HCT 116 C91(1.12); C558(3.17); C555(3.30)  LDD0685  [14]
 LDCM0369  CL100 HCT 116 C94(0.69); C555(0.93); C91(0.95); C558(0.97)  LDD0686  [14]
 LDCM0370  CL101 HCT 116 C558(1.08); C555(1.46); C91(1.51)  LDD0687  [14]
 LDCM0371  CL102 HCT 116 C558(1.15); C91(1.26); C555(1.54)  LDD0688  [14]
 LDCM0372  CL103 HCT 116 C558(0.97); C91(0.99); C555(1.19)  LDD0689  [14]
 LDCM0373  CL104 HCT 116 C558(0.92); C91(1.11); C555(1.24)  LDD0690  [14]
 LDCM0374  CL105 HCT 116 C94(0.92); C91(0.92); C555(1.44); C558(1.63)  LDD0691  [14]
 LDCM0375  CL106 HCT 116 C94(0.83); C91(0.83); C558(1.19); C555(1.24)  LDD0692  [14]
 LDCM0376  CL107 HCT 116 C91(0.92); C94(0.96); C555(1.16); C558(1.16)  LDD0693  [14]
 LDCM0377  CL108 HCT 116 C94(0.79); C91(0.89); C558(1.33); C555(1.55)  LDD0694  [14]
 LDCM0378  CL109 HCT 116 C91(0.98); C94(1.05); C555(1.43); C558(1.60)  LDD0695  [14]
 LDCM0379  CL11 HCT 116 C558(2.13); C91(2.41); C555(3.07)  LDD0696  [14]
 LDCM0380  CL110 HCT 116 C558(1.00); C94(1.20); C91(1.44); C555(1.48)  LDD0697  [14]
 LDCM0381  CL111 HCT 116 C94(1.00); C558(1.23); C555(1.41); C91(1.45)  LDD0698  [14]
 LDCM0382  CL112 HCT 116 C94(1.03); C91(1.12); C555(1.42)  LDD0699  [14]
 LDCM0383  CL113 HCT 116 C94(0.88); C91(1.16); C555(1.67)  LDD0700  [14]
 LDCM0384  CL114 HCT 116 C94(0.94); C91(1.53); C555(1.89)  LDD0701  [14]
 LDCM0385  CL115 HCT 116 C94(1.02); C91(1.53); C555(2.26)  LDD0702  [14]
 LDCM0386  CL116 HCT 116 C94(0.92); C91(1.28); C555(1.56)  LDD0703  [14]
 LDCM0387  CL117 HCT 116 C94(1.44); C555(2.19)  LDD0704  [14]
 LDCM0388  CL118 HCT 116 C94(1.02); C555(1.11)  LDD0705  [14]
 LDCM0389  CL119 HCT 116 C94(1.00); C555(1.01)  LDD0706  [14]
 LDCM0390  CL12 HCT 116 C91(0.44); C555(1.23); C558(1.61)  LDD0707  [14]
 LDCM0391  CL120 HCT 116 C555(0.79); C94(0.85)  LDD0708  [14]
 LDCM0392  CL121 HCT 116 C555(0.84); C558(0.90); C91(1.14)  LDD0709  [14]
 LDCM0393  CL122 HCT 116 C558(1.04); C555(1.45); C91(1.79)  LDD0710  [14]
 LDCM0394  CL123 HCT 116 C558(1.55); C555(2.95); C91(3.02)  LDD0711  [14]
 LDCM0395  CL124 HCT 116 C91(0.87); C558(0.98); C555(1.05)  LDD0712  [14]
 LDCM0396  CL125 HCT 116 C91(0.95); C555(1.09); C94(1.10); C558(1.19)  LDD0713  [14]
 LDCM0397  CL126 HCT 116 C94(1.18); C558(1.85); C91(2.26); C555(2.34)  LDD0714  [14]
 LDCM0398  CL127 HCT 116 C558(1.09); C94(1.17); C555(1.22); C91(1.24)  LDD0715  [14]
 LDCM0399  CL128 HCT 116 C94(0.80); C91(1.09); C555(1.28); C558(1.40)  LDD0716  [14]
 LDCM0400  CL13 HCT 116 C91(3.15); C558(4.15); C555(5.80)  LDD0717  [14]
 LDCM0401  CL14 HCT 116 C558(1.81); C555(1.84); C91(2.10)  LDD0718  [14]
 LDCM0402  CL15 HCT 116 C558(2.19); C91(2.43); C555(2.66)  LDD0719  [14]
 LDCM0403  CL16 HCT 116 C91(1.13); C555(1.29); C558(1.37)  LDD0720  [14]
 LDCM0404  CL17 HCT 116 C558(1.34); C91(1.97); C555(2.03)  LDD0721  [14]
 LDCM0405  CL18 HCT 116 C558(0.85); C555(1.06); C91(1.36)  LDD0722  [14]
 LDCM0406  CL19 HCT 116 C558(0.94); C555(1.16); C91(1.34)  LDD0723  [14]
 LDCM0407  CL2 HCT 116 C558(1.06); C555(1.41); C91(1.87)  LDD0724  [14]
 LDCM0408  CL20 HCT 116 C558(1.04); C555(1.29); C91(1.32)  LDD0725  [14]
 LDCM0409  CL21 HCT 116 C558(0.80); C555(1.33); C91(1.54)  LDD0726  [14]
 LDCM0410  CL22 HCT 116 C558(0.94); C91(1.74); C555(1.76)  LDD0727  [14]
 LDCM0411  CL23 HCT 116 C555(1.14); C91(1.23); C558(1.27)  LDD0728  [14]
 LDCM0412  CL24 HCT 116 C558(0.74); C555(1.14); C91(1.45)  LDD0729  [14]
 LDCM0413  CL25 HCT 116 C555(1.84); C91(1.96); C558(1.21)  LDD0730  [14]
 LDCM0414  CL26 HCT 116 C555(1.16); C91(1.25); C558(0.98)  LDD0731  [14]
 LDCM0415  CL27 HCT 116 C555(1.01); C91(1.09); C558(0.75)  LDD0732  [14]
 LDCM0416  CL28 HCT 116 C555(2.23); C91(2.93); C558(0.98)  LDD0733  [14]
 LDCM0417  CL29 HCT 116 C555(1.11); C91(0.77); C558(0.93)  LDD0734  [14]
 LDCM0418  CL3 HCT 116 C555(1.01); C91(1.00); C558(0.94)  LDD0735  [14]
 LDCM0419  CL30 HCT 116 C555(0.89); C91(1.14); C558(0.64)  LDD0736  [14]
 LDCM0420  CL31 HCT 116 C555(2.05); C91(2.68); C94(2.16); C558(0.59)  LDD0737  [14]
 LDCM0421  CL32 HCT 116 C555(1.73); C91(1.54); C94(1.94)  LDD0738  [14]
 LDCM0422  CL33 HCT 116 C555(5.78); C91(2.93); C94(4.16)  LDD0739  [14]
 LDCM0423  CL34 HCT 116 C555(2.30); C91(1.75); C94(2.94)  LDD0740  [14]
 LDCM0424  CL35 HCT 116 C555(1.72); C91(1.65); C94(1.92)  LDD0741  [14]
 LDCM0425  CL36 HCT 116 C555(2.36); C91(1.91); C94(2.92)  LDD0742  [14]
 LDCM0426  CL37 HCT 116 C555(2.00); C91(1.75); C94(1.84)  LDD0743  [14]
 LDCM0428  CL39 HCT 116 C555(6.11); C91(3.32); C94(4.04)  LDD0745  [14]
 LDCM0429  CL4 HCT 116 C555(1.39); C91(1.67); C558(1.11)  LDD0746  [14]
 LDCM0430  CL40 HCT 116 C555(2.86); C91(5.59); C94(1.83)  LDD0747  [14]
 LDCM0431  CL41 HCT 116 C555(2.00); C91(1.49); C94(1.94)  LDD0748  [14]
 LDCM0432  CL42 HCT 116 C555(2.69); C91(2.97); C94(2.76)  LDD0749  [14]
 LDCM0433  CL43 HCT 116 C555(2.93); C91(2.84); C94(2.62)  LDD0750  [14]
 LDCM0434  CL44 HCT 116 C555(2.62); C91(2.43); C94(2.70)  LDD0751  [14]
 LDCM0435  CL45 HCT 116 C555(2.27); C91(1.80); C94(2.03)  LDD0752  [14]
 LDCM0436  CL46 HCT 116 C555(0.88); C91(1.06)  LDD0753  [14]
 LDCM0437  CL47 HCT 116 C555(1.31); C91(1.48)  LDD0754  [14]
 LDCM0438  CL48 HCT 116 C555(0.77); C91(0.82)  LDD0755  [14]
 LDCM0439  CL49 HCT 116 C555(0.76); C91(0.78)  LDD0756  [14]
 LDCM0440  CL5 HCT 116 C555(0.99); C91(0.98); C558(0.92)  LDD0757  [14]
 LDCM0441  CL50 HCT 116 C555(0.76); C91(0.78)  LDD0758  [14]
 LDCM0442  CL51 HCT 116 C555(0.66); C91(0.75)  LDD0759  [14]
 LDCM0443  CL52 HCT 116 C555(0.64); C91(0.71)  LDD0760  [14]
 LDCM0444  CL53 HCT 116 C555(1.18); C91(1.57)  LDD0761  [14]
 LDCM0445  CL54 HCT 116 C555(0.89); C91(0.97)  LDD0762  [14]
 LDCM0446  CL55 HCT 116 C555(0.62); C91(0.70)  LDD0763  [14]
 LDCM0447  CL56 HCT 116 C555(1.57); C91(1.59)  LDD0764  [14]
 LDCM0448  CL57 HCT 116 C555(4.04); C91(2.36)  LDD0765  [14]
 LDCM0449  CL58 HCT 116 C555(0.62); C91(0.72)  LDD0766  [14]
 LDCM0450  CL59 HCT 116 C555(0.71); C91(0.77)  LDD0767  [14]
 LDCM0451  CL6 HCT 116 C555(1.01); C91(1.16); C558(0.95)  LDD0768  [14]
 LDCM0452  CL60 HCT 116 C555(1.11); C91(1.15)  LDD0769  [14]
 LDCM0453  CL61 HCT 116 C555(1.16); C91(1.16)  LDD0770  [14]
 LDCM0454  CL62 HCT 116 C555(1.18); C91(1.20)  LDD0771  [14]
 LDCM0455  CL63 HCT 116 C555(1.57); C91(1.34)  LDD0772  [14]
 LDCM0456  CL64 HCT 116 C555(1.23); C91(1.25)  LDD0773  [14]
 LDCM0457  CL65 HCT 116 C555(1.32); C91(1.23)  LDD0774  [14]
 LDCM0458  CL66 HCT 116 C555(2.55); C91(2.50)  LDD0775  [14]
 LDCM0459  CL67 HCT 116 C555(1.42); C91(1.36)  LDD0776  [14]
 LDCM0460  CL68 HCT 116 C555(2.70); C91(2.69)  LDD0777  [14]
 LDCM0461  CL69 HCT 116 C555(1.92); C91(1.82)  LDD0778  [14]
 LDCM0462  CL7 HCT 116 C555(0.97); C91(0.53); C558(1.06)  LDD0779  [14]
 LDCM0463  CL70 HCT 116 C555(1.08); C91(1.15)  LDD0780  [14]
 LDCM0464  CL71 HCT 116 C555(1.41); C91(1.26)  LDD0781  [14]
 LDCM0465  CL72 HCT 116 C555(1.20); C91(1.15)  LDD0782  [14]
 LDCM0466  CL73 HCT 116 C555(1.65); C91(1.52)  LDD0783  [14]
 LDCM0467  CL74 HCT 116 C555(1.54); C91(1.38)  LDD0784  [14]
 LDCM0469  CL76 HCT 116 C555(1.58); C91(1.60); C94(1.41); C558(1.25)  LDD0786  [14]
 LDCM0470  CL77 HCT 116 C555(3.07); C91(2.62); C94(1.54); C558(1.40)  LDD0787  [14]
 LDCM0471  CL78 HCT 116 C555(1.44); C91(1.37); C94(1.35); C558(1.37)  LDD0788  [14]
 LDCM0472  CL79 HCT 116 C555(1.79); C91(1.75); C94(1.56); C558(1.27)  LDD0789  [14]
 LDCM0473  CL8 HCT 116 C555(6.41); C91(8.13); C558(3.15)  LDD0790  [14]
 LDCM0474  CL80 HCT 116 C555(1.44); C91(1.44); C94(1.54); C558(1.21)  LDD0791  [14]
 LDCM0475  CL81 HCT 116 C555(1.57); C91(1.50); C94(1.37); C558(1.32)  LDD0792  [14]
 LDCM0476  CL82 HCT 116 C555(1.84); C91(1.78); C94(1.85); C558(1.25)  LDD0793  [14]
 LDCM0477  CL83 HCT 116 C555(1.84); C91(1.73); C94(1.66); C558(1.49)  LDD0794  [14]
 LDCM0478  CL84 HCT 116 C555(1.91); C91(2.05); C94(1.75); C558(0.88)  LDD0795  [14]
 LDCM0479  CL85 HCT 116 C555(1.43); C91(1.43); C94(1.50); C558(1.15)  LDD0796  [14]
 LDCM0480  CL86 HCT 116 C555(1.91); C91(1.80); C94(1.59); C558(1.31)  LDD0797  [14]
 LDCM0481  CL87 HCT 116 C555(3.16); C91(3.19); C94(2.62); C558(1.94)  LDD0798  [14]
 LDCM0482  CL88 HCT 116 C555(1.61); C91(1.62); C94(1.45); C558(0.99)  LDD0799  [14]
 LDCM0483  CL89 HCT 116 C555(1.80); C91(1.76); C94(1.48); C558(0.78)  LDD0800  [14]
 LDCM0484  CL9 HCT 116 C555(1.12); C91(0.96); C558(1.27)  LDD0801  [14]
 LDCM0485  CL90 HCT 116 C555(7.85); C91(4.97); C94(2.06); C558(2.18)  LDD0802  [14]
 LDCM0486  CL91 HCT 116 C555(1.56); C91(1.63); C94(1.48); C558(1.24)  LDD0803  [14]
 LDCM0487  CL92 HCT 116 C555(1.89); C91(2.16); C94(0.97); C558(1.48)  LDD0804  [14]
 LDCM0488  CL93 HCT 116 C555(1.48); C91(1.63); C94(1.13); C558(1.31)  LDD0805  [14]
 LDCM0489  CL94 HCT 116 C555(1.70); C91(2.01); C94(1.07); C558(1.38)  LDD0806  [14]
 LDCM0490  CL95 HCT 116 C555(1.52); C91(1.64); C94(1.20); C558(1.30)  LDD0807  [14]
 LDCM0491  CL96 HCT 116 C555(1.15); C91(1.24); C94(0.89); C558(0.92)  LDD0808  [14]
 LDCM0492  CL97 HCT 116 C555(1.08); C91(1.11); C94(0.83); C558(0.96)  LDD0809  [14]
 LDCM0493  CL98 HCT 116 C555(1.29); C91(1.36); C94(1.05); C558(1.21)  LDD0810  [14]
 LDCM0494  CL99 HCT 116 C555(1.44); C91(1.44); C94(1.15); C558(1.33)  LDD0811  [14]
 LDCM0168  Crenolanib NCI-H1703 2.60  LDD0429  [27]
 LDCM0495  E2913 HEK-293T C555(5.20); C206(7.26); C91(2.28); C555(5.17)  LDD1698  [31]
 LDCM0572  Fragment10 MDA-MB-231 C206(20.00); C555(13.10)  LDD1389  [32]
 LDCM0573  Fragment11 MDA-MB-231 C555(20.00)  LDD1391  [32]
 LDCM0574  Fragment12 MDA-MB-231 C206(8.46); C555(20.00)  LDD1393  [32]
 LDCM0575  Fragment13 MDA-MB-231 C206(2.02); C555(2.06)  LDD1395  [32]
 LDCM0576  Fragment14 MDA-MB-231 C206(0.94); C555(0.99)  LDD1397  [32]
 LDCM0577  Fragment15 MDA-MB-231 C206(0.70); C555(0.70)  LDD1399  [32]
 LDCM0579  Fragment20 MDA-MB-231 C206(1.75); C555(1.86)  LDD1402  [32]
 LDCM0580  Fragment21 MDA-MB-231 C206(1.42); C555(1.80)  LDD1404  [32]
 LDCM0581  Fragment22 MDA-MB-231 C206(2.15); C555(1.93)  LDD1406  [32]
 LDCM0582  Fragment23 MDA-MB-231 C206(0.89); C555(0.91)  LDD1408  [32]
 LDCM0583  Fragment24 Ramos C206(1.66); C555(1.32)  LDD1410  [32]
 LDCM0584  Fragment25 MDA-MB-231 C206(0.98); C555(0.96)  LDD1411  [32]
 LDCM0585  Fragment26 Ramos C206(0.67); C555(0.77)  LDD1412  [32]
 LDCM0578  Fragment27 MDA-MB-231 C206(0.86); C555(0.80)  LDD1401  [32]
 LDCM0586  Fragment28 MDA-MB-231 C206(1.37); C555(1.19)  LDD1415  [32]
 LDCM0587  Fragment29 MDA-MB-231 C206(1.06); C555(0.89)  LDD1417  [32]
 LDCM0588  Fragment30 MDA-MB-231 C206(2.42); C555(2.90)  LDD1419  [32]
 LDCM0589  Fragment31 MDA-MB-231 C206(0.95); C555(0.96)  LDD1421  [32]
 LDCM0590  Fragment32 MDA-MB-231 C206(20.00); C555(20.00)  LDD1423  [32]
 LDCM0468  Fragment33 HCT 116 C555(2.42); C91(1.93)  LDD0785  [14]
 LDCM0592  Fragment34 MDA-MB-231 C206(0.68); C555(0.67)  LDD1427  [32]
 LDCM0593  Fragment35 MDA-MB-231 C206(0.86); C555(0.88)  LDD1429  [32]
 LDCM0594  Fragment36 MDA-MB-231 C206(20.00)  LDD1431  [32]
 LDCM0595  Fragment37 Ramos C206(1.10); C555(0.92)  LDD1432  [32]
 LDCM0596  Fragment38 MDA-MB-231 C206(1.08); C555(1.14)  LDD1433  [32]
 LDCM0597  Fragment39 MDA-MB-231 C206(7.57); C555(3.14)  LDD1435  [32]
 LDCM0566  Fragment4 MDA-MB-231 C206(1.68); C555(1.31)  LDD1378  [32]
 LDCM0598  Fragment40 MDA-MB-231 C206(0.86); C555(0.74)  LDD1436  [32]
 LDCM0599  Fragment41 MDA-MB-231 C206(0.99); C555(0.99)  LDD1438  [32]
 LDCM0600  Fragment42 Ramos C206(0.92); C555(0.89)  LDD1440  [32]
 LDCM0601  Fragment43 MDA-MB-231 C206(20.00); C555(20.00)  LDD1441  [32]
 LDCM0602  Fragment44 MDA-MB-231 C206(0.98); C555(0.94)  LDD1443  [32]
 LDCM0603  Fragment45 MDA-MB-231 C206(1.35)  LDD1444  [32]
 LDCM0604  Fragment46 MDA-MB-231 C206(0.82); C555(0.92)  LDD1445  [32]
 LDCM0605  Fragment47 MDA-MB-231 C206(0.96); C555(0.93)  LDD1446  [32]
 LDCM0606  Fragment48 MDA-MB-231 C206(1.15)  LDD1447  [32]
 LDCM0607  Fragment49 MDA-MB-231 C206(7.33)  LDD1448  [32]
 LDCM0608  Fragment50 MDA-MB-231 C206(1.70); C555(1.51)  LDD1449  [32]
 LDCM0427  Fragment51 HCT 116 C555(3.69); C91(2.13); C94(2.50)  LDD0744  [14]
 LDCM0610  Fragment52 MDA-MB-231 C206(0.96); C555(1.01)  LDD1452  [32]
 LDCM0611  Fragment53 MDA-MB-231 C206(0.91); C555(0.93)  LDD1454  [32]
 LDCM0612  Fragment54 MDA-MB-231 C206(1.32)  LDD1456  [32]
 LDCM0613  Fragment55 MDA-MB-231 C206(1.06)  LDD1457  [32]
 LDCM0614  Fragment56 MDA-MB-231 C206(0.99); C555(0.98)  LDD1458  [32]
 LDCM0568  Fragment6 MDA-MB-231 C206(1.02); C555(1.05)  LDD1382  [32]
 LDCM0569  Fragment7 MDA-MB-231 C206(0.90); C555(0.85)  LDD1383  [32]
 LDCM0570  Fragment8 MDA-MB-231 C206(12.39); C555(12.79)  LDD1385  [32]
 LDCM0571  Fragment9 MDA-MB-231 C206(0.90); C555(0.88)  LDD1387  [32]
 LDCM0116  HHS-0101 DM93 Y137(0.77); Y252(0.81); Y392(0.87); Y273(1.02)  LDD0264  [12]
 LDCM0117  HHS-0201 DM93 Y551(0.67); Y137(0.71); Y252(0.72); Y392(0.73)  LDD0265  [12]
 LDCM0118  HHS-0301 DM93 Y273(0.73); Y551(0.76); Y392(0.83); Y252(0.85)  LDD0266  [12]
 LDCM0119  HHS-0401 DM93 Y392(0.77); Y551(0.77); Y273(0.83); Y252(0.94)  LDD0267  [12]
 LDCM0120  HHS-0701 DM93 Y551(0.45); Y392(0.47); Y252(0.54); Y273(0.62)  LDD0268  [12]
 LDCM0107  IAA HeLa H337(0.00); H634(0.00); H372(0.00); H399(0.00)  LDD0221  [24]
 LDCM0123  JWB131 DM93 Y252(1.20); Y273(0.87); Y392(2.55)  LDD0285  [11]
 LDCM0124  JWB142 DM93 Y252(1.50); Y273(1.27); Y392(1.65)  LDD0286  [11]
 LDCM0125  JWB146 DM93 Y252(1.51); Y273(1.13); Y392(2.23)  LDD0287  [11]
 LDCM0126  JWB150 DM93 Y252(8.11); Y273(4.45); Y392(15.16)  LDD0288  [11]
 LDCM0127  JWB152 DM93 Y252(3.48); Y273(3.98); Y392(8.10)  LDD0289  [11]
 LDCM0128  JWB198 DM93 Y252(0.28); Y273(1.98); Y392(4.73)  LDD0290  [11]
 LDCM0129  JWB202 DM93 Y252(1.69); Y273(1.49); Y392(2.08)  LDD0291  [11]
 LDCM0130  JWB211 DM93 Y252(1.09); Y273(2.70); Y392(2.52)  LDD0292  [11]
 LDCM0022  KB02 HCT 116 C555(9.89); C94(9.01); C91(6.14); C558(3.61)  LDD0080  [14]
 LDCM0023  KB03 HCT 116 C555(9.75); C94(14.19); C91(7.92); C558(5.82)  LDD0081  [14]
 LDCM0024  KB05 HCT 116 C555(1.22); C94(1.20); C91(1.20); C558(1.12)  LDD0082  [14]
 LDCM0109  NEM HeLa H337(0.00); H372(0.00); H338(0.00); H634(0.00)  LDD0223  [24]
 LDCM0627  NUDT7-COV-1 HEK-293T C555(0.93)  LDD2206  [33]
 LDCM0131  RA190 MM1.R C91(1.14); C94(1.14); C206(1.08); C209(1.08)  LDD0304  [34]
 LDCM0019  Staurosporine Hep-G2 2.44  LDD0083  [28]
 LDCM0021  THZ1 HCT 116 C555(1.24); C558(1.24); C91(1.25); C94(1.25)  LDD2173  [14]
 LDCM0112  W16 Hep-G2 C558(1.33); C555(1.38)  LDD0239  [3]
 LDCM0113  W17 Hep-G2 C558(1.82)  LDD0240  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Peptidyl-prolyl cis-trans isomerase B (PPIB) Cyclophilin-type PPIase family P23284
Other
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Neutrophil gelatinase-associated lipocalin (LCN2) Lipocalin family P80188
Keratin-associated protein 10-8 (KRTAP10-8) KRTAP type 10 family P60410
Keratin-associated protein 12-1 (KRTAP12-1) KRTAP type 12 family P59990
Keratin-associated protein 4-11 (KRTAP4-11) KRTAP type 4 family Q9BYQ6
Matrilin-3 (MATN3) . O15232

References

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Mass spectrometry data entry: PXD037665
3 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
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5 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
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Mass spectrometry data entry: PXD028270
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Mass spectrometry data entry: PXD042888
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Mass spectrometry data entry: PXD044625
11 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
12 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
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15 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
16 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
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Mass spectrometry data entry: PXD028853
18 Comparison of Quantitative Mass Spectrometry Platforms for Monitoring Kinase ATP Probe Uptake in Lung Cancer. J Proteome Res. 2018 Jan 5;17(1):63-75. doi: 10.1021/acs.jproteome.7b00329. Epub 2017 Nov 22.
Mass spectrometry data entry: PXD006095 , PXD006096
19 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
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Mass spectrometry data entry: PXD022279
21 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
22 Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529022. doi: 10.1101/2023.02.17.529022.
Mass spectrometry data entry: PXD039931
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Mass spectrometry data entry: PXD033004
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30 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
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Mass spectrometry data entry: PXD044402
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33 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.
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