General Information of Competitor

Competitor ID
LDCM0128
Competitor Name
JWB198
Synonyms
SCHEMBL22558798
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 336.4
Lipid-water partition coefficient (xlogp) 3.1
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C17H12N4O2S
IUPAC Name
4-(1-naphthalen-2-ylsulfonyl-1,2,4-triazol-3-yl)pyridine
Canonical SMILES
C1=CC=C2C=C(C=CC2=C1)S(=O)(=O)N3C=NC(=N3)C4=CC=NC=C4
InChI
InChI=1S/C17H12N4O2S/c22-24(23,16-6-5-13-3-1-2-4-15(13)11-16)21-12-19-17(20-21)14-7-9-18-10-8-14/h1-12H
InChIKey
ZOEPIMUDPBJJPH-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
HHS-482
 Probe Info 
50 uM Human melanoma cell lysate (DM93) [1]

Target(s) List of this Competitor

290 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
(3R)-3-hydroxyacyl-CoA dehydrogenase (HSD17B8) LDTP09770 1.08  LDD0290 
1,4-alpha-glucan-branching enzyme (GBE1) LDTP05419 4.45  LDD0290 
14 kDa phosphohistidine phosphatase (PHPT1) LDTP12543 2.02; 2.08  LDD0290 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 0.13; 5.23  LDD0290 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 2.58  LDD0290 
26S proteasome non-ATPase regulatory subunit 3 (PSMD3) LDTP00714 2.10  LDD0290 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 0.90  LDD0290 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 1.04  LDD0290 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 0.93  LDD0290 
26S proteasome regulatory subunit 7 (PSMC2) LDTP03797 0.19  LDD0290 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 0.69  LDD0290 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 3.01  LDD0290 
5'-3' exoribonuclease 2 (XRN2) LDTP11701 0.37  LDD0290 
6-phosphogluconate dehydrogenase, decarboxylating (PGD) LDTP04499 0.05  LDD0290 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 0.19; 1.38; 0.89 ...  LDD0290 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 1.17  LDD0290 
Acetyl-CoA carboxylase 1 (ACACA) LDTP05742 0.89  LDD0290 
Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) LDTP12463 1.28  LDD0290 
Actin, alpha cardiac muscle 1 (ACTC1) LDTP05069 1.03  LDD0290 
Actin, cytoplasmic 1 (ACTB) LDTP04876 0.67; 1.79; 1.05 ...  LDD0290 
Acylamino-acid-releasing enzyme (APEH) LDTP02693 0.67  LDD0290 
Adenosylhomocysteinase (AHCY) LDTP03242 1.04; 0.69  LDD0290 
Adenylosuccinate synthetase isozyme 2 (ADSS2) LDTP03541 0.21  LDD0290 
ADP-ribose pyrophosphatase, mitochondrial (NUDT9) LDTP11318 0.59  LDD0290 
ADP-ribosylation factor 1 (ARF1) LDTP05192 1.55; 1.29  LDD0290 
ADP-ribosylation factor 3 (ARF3) LDTP04907 1.55; 1.29  LDD0290 
ADP-ribosylation factor 4 (ARF4) LDTP02942 1.55; 1.29  LDD0290 
ADP-ribosylation factor 5 (ARF5) LDTP05193 1.55; 1.29  LDD0290 
ADP-sugar pyrophosphatase (NUDT5) LDTP13462 0.81  LDD0290 
Aflatoxin B1 aldehyde reductase member 2 (AKR7A2) LDTP00776 0.54; 0.16; 0.14 ...  LDD0290 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 0.59; 0.27  LDD0290 
Alcohol dehydrogenase class-3 (ADH5) LDTP02587 1.10; 0.27; 1.15  LDD0290 
Aldo-keto reductase family 1 member A1 (AKR1A1) LDTP02729 1.14  LDD0290 
Alpha-aminoadipic semialdehyde synthase, mitochondrial (AASS) LDTP13186 0.09; 0.17; 0.06  LDD0290 
Alpha-enolase (ENO1) LDTP02159 0.63; 0.81; 2.89 ...  LDD0290 
Amidophosphoribosyltransferase (PPAT) LDTP05480 1.23  LDD0290 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 0.05; 0.57  LDD0290 
Asparagine synthetase [glutamine-hydrolyzing] (ASNS) LDTP02264 5.12; 0.73  LDD0290 
Asparagine--tRNA ligase, cytoplasmic (NARS1) LDTP00866 3.23; 0.27  LDD0290 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 6.23; 1.19; 0.67  LDD0290 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 0.61; 1.19; 1.22  LDD0290 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 1.23  LDD0290 
ATP-citrate synthase (ACLY) LDTP04561 1.29; 1.06; 1.76 ...  LDD0290 
ATP-dependent 6-phosphofructokinase, liver type (PFKL) LDTP02925 0.92  LDD0290 
ATP-dependent 6-phosphofructokinase, muscle type (PFKM) LDTP02261 3.28  LDD0290 
ATP-dependent RNA helicase A (DHX9) LDTP05550 0.76; 1.10  LDD0290 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 1.29  LDD0290 
ATPase MORC2 (MORC2) LDTP14308 1.80  LDD0290 
Bifunctional coenzyme A synthase (COASY) LDTP05736 1.31  LDD0290 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 0.54  LDD0290 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 1.91  LDD0290 
Biliverdin reductase A (BLVRA) LDTP04552 0.85  LDD0290 
Biotinidase (BTD) LDTP04030 3.69  LDD0290 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 3.66; 0.69; 0.75 ...  LDD0290 
Calcyclin-binding protein (CACYBP) LDTP12163 1.08; 2.41; 1.63  LDD0290 
Carbonyl reductase [NADPH] 1 (CBR1) LDTP02831 2.03  LDD0290 
Carbonyl reductase [NADPH] 3 (CBR3) LDTP01321 1.03  LDD0290 
Catalase (CAT) LDTP02001 1.69  LDD0290 
Cathepsin B (CTSB) LDTP02223 1.07; 1.03; 1.02 ...  LDD0290 
Cathepsin D (CTSD) LDTP02198 0.57  LDD0290 
Cathepsin Z (CTSZ) LDTP13147 0.81; 1.46; 2.37 ...  LDD0290 
Citrate synthase, mitochondrial (CS) LDTP01205 0.26; 1.54; 1.09  LDD0290 
Cleavage and polyadenylation specificity factor subunit 5 (NUDT21) LDTP00873 0.24  LDD0290 
CTP synthase 1 (CTPS1) LDTP02922 1.28; 1.49  LDD0290 
Cyclin-dependent kinase 1 (CDK1) LDTP02149 0.58; 2.57; 1.06 ...  LDD0290 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 0.58; 1.06; 4.42  LDD0290 
Cystathionine gamma-lyase (CTH) LDTP03656 0.69  LDD0290 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 0.74  LDD0290 
Cytochrome c oxidase assembly factor 7 (COA7) LDTP10137 1.03  LDD0290 
Cytoglobin (CYGB) LDTP09656 0.95; 1.63  LDD0290 
Cytosol aminopeptidase (LAP3) LDTP03455 0.96  LDD0290 
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 7.33; 0.81  LDD0290 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 1.77  LDD0290 
Dehydrogenase/reductase SDR family member 11 (DHRS11) LDTP07678 0.54  LDD0290 
Dihydropteridine reductase (QDPR) LDTP02342 1.31  LDD0290 
Dihydropyrimidinase-related protein 3 (DPYSL3) LDTP06079 2.98  LDD0290 
Dipeptidyl peptidase 3 (DPP3) LDTP12803 0.88  LDD0290 
DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 0.16  LDD0290 
DNA replication licensing factor MCM2 (MCM2) LDTP04286 1.04  LDD0290 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 0.87  LDD0290 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 0.51  LDD0290 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 0.05  LDD0290 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 2.25  LDD0295 
DNA replication licensing factor MCM7 (MCM7) LDTP03682 0.15  LDD0290 
Dual specificity protein phosphatase 23 (DUSP23) LDTP11289 1.00  LDD0290 
Dual specificity protein phosphatase 3 (DUSP3) LDTP04415 1.93  LDD0290 
E3 ubiquitin-protein ligase ARIH2 (ARIH2) LDTP01575 1.26  LDD0290 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 1.29  LDD0290 
E3 ubiquitin-protein ligase UBR4 (UBR4) LDTP07118 1.28  LDD0290 
EH domain-containing protein 4 (EHD4) LDTP11788 0.58  LDD0290 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 1.62; 1.06; 1.13 ...  LDD0290 
Elongation factor 2 (EEF2) LDTP02672 1.12; 0.65; 6.50 ...  LDD0290 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 0.46; 0.72; 0.45 ...  LDD0290 
Endoplasmic reticulum chaperone BiP (HSPA5) LDTP02534 8.54; 1.15; 0.56 ...  LDD0290 
Enoyl-CoA hydratase, mitochondrial (ECHS1) LDTP03518 0.78  LDD0290 
ERO1-like protein alpha (ERO1A) LDTP10386 0.14; 1.69  LDD0290 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 1.43; 0.85; 1.45 ...  LDD0290 
Eukaryotic initiation factor 4A-II (EIF4A2) LDTP06089 1.38; 1.09; 0.97  LDD0295 
Eukaryotic initiation factor 4A-III (EIF4A3) LDTP03861 1.23  LDD0290 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 0.58  LDD0290 
Exosome complex exonuclease RRP44 (DIS3) LDTP13887 0.62  LDD0290 
Farnesyl pyrophosphate synthase (FDPS) LDTP02721 2.51  LDD0290 
Fatty acid CoA ligase Acsl3 (ACSL3) LDTP01634 4.93; 1.27  LDD0290 
Fatty acid synthase (FASN) LDTP04243 1.58; 1.22; 1.25 ...  LDD0290 
Flap endonuclease 1 (FEN1) LDTP03872 1.19  LDD0290 
Fructose-2,6-bisphosphatase TIGAR (TIGAR) LDTP12405 0.90  LDD0290 
Fructose-bisphosphate aldolase A (ALDOA) LDTP02008 1.22; 1.60; 1.33 ...  LDD0290 
Fumarate hydratase, mitochondrial (FH) LDTP02235 0.40  LDD0290 
Fumarylacetoacetase (FAH) LDTP02868 1.37  LDD0290 
Galactokinase (GALK1) LDTP04424 0.88  LDD0290 
Gamma-enolase (ENO2) LDTP02328 0.22; 0.50  LDD0290 
GDP-mannose 4,6 dehydratase (GMDS) LDTP00999 0.69  LDD0290 
Geranylgeranyl transferase type-2 subunit beta (RABGGTB) LDTP04569 1.27  LDD0290 
Glucosamine-6-phosphate isomerase 1 (GNPDA1) LDTP04113 0.34  LDD0290 
Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 0.65; 0.14  LDD0290 
Glucose-6-phosphate isomerase (GPI) LDTP02162 0.10; 1.27; 0.12  LDD0290 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) LDTP05481 0.90; 0.64  LDD0290 
Glutaredoxin-1 (GLRX) LDTP03786 1.94  LDD0290 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 1.29; 0.67  LDD0290 
Glutathione S-transferase A4 (GSTA4) LDTP00575 20.00  LDD0290 
Glutathione S-transferase kappa 1 (GSTK1) LDTP13900 0.51  LDD0290 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 0.28  LDD0290 
Glutathione S-transferase P (GSTP1) LDTP02333 0.73; 1.03; 0.62 ...  LDD0290 
Glutathione synthetase (GSS) LDTP04200 1.07  LDD0290 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 1.47; 0.93; 1.19 ...  LDD0290 
Glycine--tRNA ligase (GARS1) LDTP03946 0.93; 1.46; 0.62 ...  LDD0290 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 1.15; 1.16; 1.49 ...  LDD0290 
Glycogen phosphorylase, liver form (PYGL) LDTP02161 0.98  LDD0290 
Glycogen synthase kinase-3 alpha (GSK3A) LDTP04318 1.98  LDD0290 
Glycogen synthase kinase-3 beta (GSK3B) LDTP04319 1.98  LDD0290 
GTP-binding nuclear protein Ran (RAN) LDTP05007 1.28; 0.66; 0.91 ...  LDD0290 
HBS1-like protein (HBS1L) LDTP14019 0.73  LDD0290 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 1.62; 1.04; 1.16 ...  LDD0290 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 0.67; 0.13; 1.24 ...  LDD0290 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 0.77  LDD0290 
Histone deacetylase 1 (HDAC1) LDTP05918 1.30  LDD0290 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 0.99  LDD0290 
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL) LDTP03794 0.59  LDD0290 
Inorganic pyrophosphatase (PPA1) LDTP14854 0.71; 2.89; 1.48 ...  LDD0290 
Inorganic pyrophosphatase 2, mitochondrial (PPA2) LDTP11842 1.78  LDD0290 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 0.30; 0.78; 0.90 ...  LDD0290 
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) LDTP11700 1.90  LDD0290 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 0.94; 0.21; 0.61 ...  LDD0290 
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A) LDTP04345 0.05  LDD0290 
Isoleucine--tRNA ligase, cytoplasmic (IARS1) LDTP03947 0.95  LDD0290 
Kynurenine--oxoglutarate transaminase 3 (KYAT3) LDTP07763 0.18; 0.11  LDD0290 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 1.23; 1.56; 0.24 ...  LDD0290 
L-lactate dehydrogenase B chain (LDHB) LDTP02179 1.21; 0.76; 1.22 ...  LDD0290 
L-xylulose reductase (DCXR) LDTP08082 2.22  LDD0290 
Lactoylglutathione lyase (GLO1) LDTP05434 2.45  LDD0290 
Lymphokine-activated killer T-cell-originated protein kinase (PBK) LDTP10500 1.23; 2.04; 1.32  LDD0290 
Macrophage migration inhibitory factor (MIF) LDTP02713 0.74; 1.85; 0.68 ...  LDD0290 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 0.67; 1.72  LDD0290 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 0.32; 0.26; 0.08 ...  LDD0290 
Mannose-1-phosphate guanyltransferase beta (GMPPB) LDTP14141 0.73  LDD0290 
MAP kinase-activated protein kinase 3 (MAPKAPK3) LDTP06589 0.05; 1.08  LDD0290 
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) LDTP02565 0.39; 0.27; 0.18  LDD0290 
Methionine adenosyltransferase 2 subunit beta (MAT2B) LDTP12915 0.86  LDD0290 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 0.88  LDD0290 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 1.89  LDD0290 
Methylthioribulose-1-phosphate dehydratase (APIP) LDTP10368 1.96  LDD0290 
Mitochondrial-processing peptidase subunit beta (PMPCB) LDTP01220 6.04  LDD0290 
Mitogen-activated protein kinase 1 (MAPK1) LDTP03445 0.32; 1.31  LDD0290 
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) LDTP01005 1.39; 1.71  LDD0290 
Myosin-10 (MYH10) LDTP03765 0.38; 2.56; 0.83 ...  LDD0290 
Myosin-9 (MYH9) LDTP03764 1.09; 2.85; 0.18 ...  LDD0290 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 0.93  LDD0290 
NAD(P)H dehydrogenase [quinone] 1 (NQO1) LDTP02798 0.78; 0.96; 1.30  LDD0290 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 1.30  LDD0290 
NEDD8-conjugating enzyme Ubc12 (UBE2M) LDTP04898 0.10  LDD0290 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 2.25  LDD0290 
Nucleoside diphosphate kinase B (NME2) LDTP03169 0.18  LDD0290 
Omega-amidase NIT2 (NIT2) LDTP12428 0.13; 1.25; 0.05 ...  LDD0290 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 1.74; 1.01; 1.15  LDD0290 
Palmitoyltransferase ZDHHC17 (ZDHHC17) LDTP08456 0.42  LDD0290 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 1.98; 1.40  LDD0290 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 1.89  LDD0290 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 1.57; 1.74  LDD0290 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 0.21; 3.62; 1.14  LDD0290 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) LDTP05912 1.50  LDD0290 
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3) LDTP11823 0.20  LDD0290 
Peroxiredoxin-1 (PRDX1) LDTP05503 0.94; 1.34; 0.28  LDD0290 
Peroxiredoxin-4 (PRDX4) LDTP05773 2.43; 1.31  LDD0290 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 0.95  LDD0290 
Phosphatidylinositide phosphatase SAC2 (INPP5F) LDTP13867 0.88  LDD0290 
Phosphoglucomutase-1 (PGM1) LDTP03818 4.63  LDD0290 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 1.85; 0.94; 1.61 ...  LDD0290 
Phosphoglycerate mutase 1 (PGAM1) LDTP02963 1.13; 4.31; 1.52 ...  LDD0290 
Phosphoserine aminotransferase (PSAT1) LDTP14198 1.99; 1.04; 0.15 ...  LDD0290 
Poly(A) polymerase alpha (PAPOLA) LDTP04394 0.87  LDD0290 
Presequence protease, mitochondrial (PITRM1) LDTP07003 0.43  LDD0290 
Probable aminopeptidase NPEPL1 (NPEPL1) LDTP09126 0.11  LDD0290 
Probable E3 ubiquitin-protein ligase IRF2BPL (IRF2BPL) LDTP11759 0.40; 1.22  LDD0290 
Prolyl endopeptidase (PREP) LDTP04163 0.67  LDD0290 
Prostaglandin reductase 1 (PTGR1) LDTP06227 0.75  LDD0290 
Prostaglandin reductase 2 (PTGR2) LDTP08979 1.20; 3.83; 6.16  LDD0290 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 1.24  LDD0290 
Proteasome subunit alpha type-2 (PSMA2) LDTP03331 1.39; 1.14; 1.41  LDD0290 
Proteasome subunit alpha type-3 (PSMA3) LDTP03332 0.92  LDD0290 
Proteasome subunit alpha type-5 (PSMA5) LDTP03413 0.31  LDD0290 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 1.26; 1.13; 0.15 ...  LDD0290 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 0.88; 1.26; 0.75 ...  LDD0290 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 1.14; 1.08  LDD0290 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 2.12; 0.84  LDD0290 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 1.08; 0.90  LDD0290 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 0.96; 1.24  LDD0290 
Protein disulfide-isomerase (P4HB) LDTP02188 0.23; 0.75; 2.04 ...  LDD0290 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 1.38; 1.97; 1.97 ...  LDD0290 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 0.28; 1.98; 4.73  LDD0290 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 1.12  LDD0290 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 1.14  LDD0290 
Protein kinase C delta type (PRKCD) LDTP05461 3.40  LDD0290 
Protein phosphatase 1G (PPM1G) LDTP00616 20.00  LDD0290 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 1.19  LDD0290 
Putative elongation factor 1-alpha-like 3 (EEF1A1P5) LDTP15029 1.62; 1.06; 1.13 ...  LDD0290 
Pyridoxine-5'-phosphate oxidase (PNPO) LDTP12691 1.17  LDD0290 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 0.13; 0.12  LDD0290 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 0.38; 0.24; 1.17 ...  LDD0290 
Pyruvate kinase PKM (PKM) LDTP02733 0.30; 1.65; 0.66 ...  LDD0290 
Queuine tRNA-ribosyltransferase catalytic subunit 1 (QTRT1) LDTP11400 1.94  LDD0290 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 0.83; 0.70  LDD0290 
RAC-gamma serine/threonine-protein kinase (AKT3) LDTP13799 1.08; 0.70  LDD0290 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 1.12  LDD0290 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 0.31; 0.15  LDD0290 
RING finger and CHY zinc finger domain-containing protein 1 (RCHY1) LDTP10686 1.04  LDD0290 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 0.26  LDD0290 
RNA demethylase ALKBH5 (ALKBH5) LDTP07547 0.83  LDD0290 
RNA-splicing ligase RtcB homolog (RTCB) LDTP13992 2.77  LDD0290 
RuvB-like 1 (RUVBL1) LDTP13816 0.22  LDD0290 
S-adenosylmethionine synthase isoform type-2 (MAT2A) LDTP03577 0.27; 0.51  LDD0290 
S-formylglutathione hydrolase (ESD) LDTP02521 1.43; 1.92  LDD0290 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 1.32  LDD0290 
Sepiapterin reductase (SPR) LDTP03730 0.11; 0.63  LDD0290 
Septin-2 (SEPTIN2) LDTP06279 1.50  LDD0290 
Septin-7 (SEPTIN7) LDTP06513 0.67; 0.62  LDD0290 
Septin-9 (SEPTIN9) LDTP13272 0.72; 0.19; 1.21  LDD0290 
Serine hydroxymethyltransferase, cytosolic (SHMT1) LDTP03688 1.09  LDD0290 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 0.10  LDD0290 
Serine/threonine-protein kinase PAK 2 (PAK2) LDTP05776 0.96  LDD0290 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 0.30  LDD0290 
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) LDTP05064 1.14; 2.65  LDD0290 
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB) LDTP04998 1.08  LDD0290 
Serine/threonine-protein phosphatase 4 catalytic subunit (PPP4C) LDTP04870 1.14  LDD0290 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 1.28  LDD0290 
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) LDTP04959 0.09; 1.19  LDD0290 
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) LDTP04960 0.09; 1.19  LDD0290 
Sialic acid synthase (NANS) LDTP12473 0.80; 1.01; 0.55  LDD0290 
Spermidine synthase (SRM) LDTP03008 0.19  LDD0290 
Spliceosome RNA helicase DDX39B (DDX39B) LDTP05991 1.35  LDD0290 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 0.75; 0.71  LDD0290 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 1.94  LDD0290 
SUMO-activating enzyme subunit 2 (UBA2) LDTP13156 1.13  LDD0290 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 0.36; 1.47; 0.11 ...  LDD0290 
Thimet oligopeptidase (THOP1) LDTP04542 0.92  LDD0290 
Thioredoxin domain-containing protein 12 (TXNDC12) LDTP01707 1.64  LDD0290 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 1.46; 1.17; 1.37 ...  LDD0290 
Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) LDTP03515 2.89  LDD0290 
Threonine--tRNA ligase 1, cytoplasmic (TARS1) LDTP03365 0.21; 0.20; 0.82 ...  LDD0290 
Thymidylate kinase (DTYMK) LDTP03258 1.12  LDD0290 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 0.81; 1.51; 1.14 ...  LDD0290 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 1.11  LDD0290 
Transketolase (TKT) LDTP03487 1.74; 0.78; 1.38 ...  LDD0290 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 0.69  LDD0290 
Triosephosphate isomerase (TPI1) LDTP04851 0.95; 4.98; 0.13  LDD0290 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 0.33  LDD0290 
Tryptophan--tRNA ligase, cytoplasmic (WARS1) LDTP03222 1.30; 0.85; 2.77 ...  LDD0290 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 1.06; 1.06; 1.04 ...  LDD0290 
Tubulin alpha-1B chain (TUBA1B) LDTP05074 1.06; 1.06; 1.04 ...  LDD0290 
Tubulin alpha-1C chain (TUBA1C) LDTP11074 1.08  LDD0290 
Tubulin--tyrosine ligase-like protein 12 (TTLL12) LDTP06067 0.05  LDD0290 
Tyrosine--tRNA ligase, cytoplasmic (YARS1) LDTP04617 0.25  LDD0290 
Tyrosine-protein kinase CSK (CSK) LDTP03944 0.81  LDD0290 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 0.30  LDD0290 
Ubiquitin carboxyl-terminal hydrolase 14 (USP14) LDTP04618 2.60  LDD0290 
Ubiquitin carboxyl-terminal hydrolase 39 (USP39) LDTP06903 0.11  LDD0290 
Ubiquitin carboxyl-terminal hydrolase 4 (USP4) LDTP05749 0.11  LDD0290 
Ubiquitin-conjugating enzyme E2 N (UBE2N) LDTP04900 1.91; 0.55; 2.04  LDD0290 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 0.89; 1.37; 1.49 ...  LDD0290 
UDP-glucose 4-epimerase (GALE) LDTP06111 4.94  LDD0290 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 0.92; 0.55; 1.12 ...  LDD0290 
UMP-CMP kinase (CMPK1) LDTP03519 0.56  LDD0290 
Unconventional myosin-Ie (MYO1E) LDTP05708 4.12  LDD0290 
Uridine 5'-monophosphate synthase (UMPS) LDTP02548 0.94  LDD0290 
Uridine phosphorylase 1 (UPP1) LDTP06643 0.86; 3.60; 0.94 ...  LDD0290 
Uroporphyrinogen decarboxylase (UROD) LDTP02135 1.45; 0.70  LDD0290 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 0.19; 0.43; 2.12  LDD0290 
V-type proton ATPase subunit E 2 (ATP6V1E2) LDTP15684 1.18  LDD0290 
Valine--tRNA ligase (VARS1) LDTP03366 1.31  LDD0290 
WD repeat-containing protein 82 (WDR82) LDTP07715 0.95  LDD0290 
Xaa-Pro aminopeptidase 1 (XPNPEP1) LDTP12444 4.75; 1.01  LDD0290 
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⏷ Show the Full List of 290 Enzyme
41 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein epsilon (YWHAE) LDTP04969 0.21; 1.15; 1.02 ...  LDD0290 
14-3-3 protein theta (YWHAQ) LDTP03385 1.08  LDD0290 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 0.41; 1.06; 1.45 ...  LDD0290 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 1.15; 0.95  LDD0290 
Alpha-crystallin B chain (CRYAB) LDTP01929 3.08  LDD0290 
Alpha-synuclein (SNCA) LDTP03848 7.24  LDD0290 
Annexin A2 (ANXA2) LDTP02199 0.17; 1.45; 0.13 ...  LDD0290 
Annexin A5 (ANXA5) LDTP02307 1.32; 1.81; 1.88 ...  LDD0290 
Annexin A6 (ANXA6) LDTP02247 1.40; 1.40  LDD0290 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 0.54  LDD0290 
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 1.03; 1.65  LDD0290 
Calreticulin (CALR) LDTP03402 1.30; 0.95; 1.94 ...  LDD0290 
Cation-independent mannose-6-phosphate receptor (IGF2R) LDTP02586 10.31  LDD0290 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 1.91; 0.70; 0.15 ...  LDD0290 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 1.98; 0.26; 0.25 ...  LDD0290 
Clathrin heavy chain 1 (CLTC) LDTP05252 0.18; 0.53  LDD0290 
Copine-3 (CPNE3) LDTP01133 1.40; 1.21  LDD0290 
Cystatin-B (CSTB) LDTP02009 1.18; 1.18; 1.31  LDD0290 
Dihydropyrimidinase-related protein 2 (DPYSL2) LDTP06554 0.63; 2.98; 1.00 ...  LDD0290 
Eukaryotic translation initiation factor 5A-1 (EIF5A) LDTP05056 3.84; 2.73  LDD0290 
Exportin-1 (XPO1) LDTP00501 1.01; 0.23  LDD0290 
Filamin-A (FLNA) LDTP03107 1.18; 1.68  LDD0290 
Galectin-3 (LGALS3) LDTP02929 0.99  LDD0290 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 0.68; 1.06; 1.16 ...  LDD0290 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 0.75  LDD0290 
Importin subunit beta-1 (KPNB1) LDTP06242 0.78; 20.00  LDD0290 
mRNA export factor RAE1 (RAE1) LDTP05122 0.90  LDD0290 
Protein SEC13 homolog (SEC13) LDTP04707 1.80  LDD0290 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 1.30; 0.31  LDD0290 
Sorting nexin-2 (SNX2) LDTP01043 0.85  LDD0290 
T-complex protein 1 subunit delta (CCT4) LDTP04391 0.51; 1.17; 0.74 ...  LDD0290 
Talin-1 (TLN1) LDTP14031 0.11; 0.22; 0.87 ...  LDD0290 
Thioredoxin domain-containing protein 17 (TXNDC17) LDTP11103 1.32  LDD0290 
Transferrin receptor protein 1 (TFRC) LDTP01969 0.13  LDD0290 
Ubiquilin-4 (UBQLN4) LDTP12533 1.02  LDD0290 
V-type proton ATPase subunit B, brain isoform (ATP6V1B2) LDTP03104 1.05  LDD0290 
V-type proton ATPase subunit C 1 (ATP6V1C1) LDTP03105 3.15  LDD0290 
V-type proton ATPase subunit E 1 (ATP6V1E1) LDTP03811 1.18  LDD0290 
V-type proton ATPase subunit G 1 (ATP6V1G1) LDTP01185 1.06  LDD0290 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 1.03  LDD0290 
Voltage-gated potassium channel subunit beta-2 (KCNAB2) LDTP05817 1.30  LDD0290 
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⏷ Show the Full List of 41 Transporter and channel
8 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
High mobility group protein B1 (HMGB1) LDTP02343 0.94; 0.10; 1.36 ...  LDD0290 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 1.67  LDD0290 
Nascent polypeptide-associated complex subunit alpha, muscle-specific form (NACA) LDTP14411 0.07  LDD0290 
Signal transducer and activator of transcription 3 (STAT3) LDTP03903 0.14  LDD0290 
Signal transducer and activator of transcription 5A (STAT5A) LDTP03971 1.90  LDD0290 
Transcription factor SOX-10 (SOX10) LDTP04752 1.27; 0.72  LDD0290 
Transcription factor SOX-9 (SOX9) LDTP04179 1.27  LDD0290 
Y-box-binding protein 1 (YBX1) LDTP05065 0.80; 1.27; 1.83  LDD0290 
------------------------------------------------------------------------------------
⏷ Show the Full List of 8 Transcription factor
268 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
10 kDa heat shock protein, mitochondrial (HSPE1) LDTP04931 2.42  LDD0290 
14-3-3 protein beta/alpha (YWHAB) LDTP03617 0.96; 1.30  LDD0290 
14-3-3 protein eta (YWHAH) LDTP05442 0.12  LDD0290 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 0.14  LDD0290 
55 kDa erythrocyte membrane protein (MPP1) LDTP05233 0.10  LDD0290 
Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) LDTP03871 0.84  LDD0290 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 0.42  LDD0290 
Actin nucleation-promoting factor WASL (WASL) LDTP00263 1.22  LDD0290 
Actin-related protein 3 (ACTR3) LDTP04902 1.26; 1.41; 0.25 ...  LDD0290 
Adapter molecule crk (CRK) LDTP04091 1.83; 0.60; 0.10  LDD0290 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 0.16; 1.20; 0.99  LDD0290 
AH receptor-interacting protein (AIP) LDTP00202 1.33  LDD0290 
Alpha-actinin-1 (ACTN1) LDTP02631 0.23; 1.58; 2.22  LDD0290 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 2.52  LDD0290 
Ankyrin repeat and MYND domain-containing protein 2 (ANKMY2) LDTP17620 1.25  LDD0290 
Ankyrin repeat domain-containing protein 39 (ANKRD39) LDTP19320 1.35  LDD0290 
Annexin A3 (ANXA3) LDTP02620 0.83  LDD0290 
Annexin A7 (ANXA7) LDTP03030 0.73  LDD0290 
Apoptosis inhibitor 5 (API5) LDTP11575 1.15  LDD0290 
Beta-parvin (PARVB) LDTP12184 0.22  LDD0290 
Bifunctional purine biosynthesis protein ATIC (ATIC) LDTP03612 1.42; 2.55; 1.21 ...  LDD0290 
Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (ARFGEF2) LDTP14237 0.77  LDD0290 
C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9) LDTP00934 1.68; 0.56  LDD0290 
Calpain small subunit 1 (CAPNS1) LDTP02047 1.26  LDD0290 
Calponin-3 (CNN3) LDTP06383 1.41; 1.31; 1.51 ...  LDD0290 
Calumenin (CALU) LDTP00887 1.10; 0.82; 0.96 ...  LDD0290 
cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) LDTP02697 0.18  LDD0290 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 1.36; 1.56; 0.77 ...  LDD0290 
Cell cycle and apoptosis regulator protein 2 (CCAR2) LDTP08760 1.71  LDD0290 
Coatomer subunit alpha (COPA) LDTP04571 1.40  LDD0290 
Coatomer subunit beta (COPB1) LDTP04570 0.86  LDD0290 
Coatomer subunit gamma-1 (COPG1) LDTP14216 1.17  LDD0290 
Cofilin-1 (CFL1) LDTP03244 1.65; 1.77; 1.14 ...  LDD0290 
Cofilin-2 (CFL2) LDTP13827 0.70; 0.71  LDD0295 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 1.63  LDD0290 
Condensin complex subunit 2 (NCAPH) LDTP06268 1.28  LDD0290 
Copper transport protein ATOX1 (ATOX1) LDTP00229 1.61  LDD0290 
Coronin-1B (CORO1B) LDTP11101 0.92  LDD0290 
Coronin-1C (CORO1C) LDTP13580 1.20  LDD0290 
Crk-like protein (CRKL) LDTP04092 1.40; 0.61; 0.94  LDD0290 
Cysteine and glycine-rich protein 1 (CSRP1) LDTP03106 1.43; 1.34; 1.94  LDD0290 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 1.36; 0.13; 0.16 ...  LDD0290 
Cytoplasmic FMR1-interacting protein 1 (CYFIP1) LDTP07958 1.87  LDD0290 
Cytotoxic granule associated RNA binding protein TIA1 (TIA1) LDTP03598 2.46  LDD0290 
Destrin (DSTN) LDTP04887 1.24  LDD0290 
DnaJ homolog subfamily A member 2 (DNAJA2) LDTP01073 0.94  LDD0290 
DnaJ homolog subfamily B member 1 (DNAJB1) LDTP03325 1.14  LDD0290 
DnaJ homolog subfamily C member 8 (DNAJC8) LDTP01361 4.25  LDD0290 
Drebrin-like protein (DBNL) LDTP13399 1.26; 1.37; 1.44  LDD0290 
Dynactin subunit 1 (DCTN1) LDTP06082 0.46  LDD0290 
Dynactin subunit 2 (DCTN2) LDTP05922 1.37  LDD0290 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 3.09  LDD0290 
Dynein light chain 2, cytoplasmic (DYNLL2) LDTP10308 1.08  LDD0290 
Elongation factor 1-beta (EEF1B2) LDTP03283 1.32; 0.70; 1.44 ...  LDD0290 
Elongation factor 1-delta (EEF1D) LDTP03499 1.09; 1.64; 0.43 ...  LDD0290 
Elongation factor 1-gamma (EEF1G) LDTP03367 1.06; 0.23; 1.78  LDD0290 
Endoplasmic reticulum resident protein 29 (ERP29) LDTP03509 1.03; 1.52  LDD0290 
Endoplasmin (HSP90B1) LDTP02734 1.01; 1.71; 1.10 ...  LDD0290 
Enhancer of mRNA-decapping protein 3 (EDC3) LDTP10299 1.16  LDD0290 
Epidermal growth factor receptor substrate 15-like 1 (EPS15L1) LDTP13097 1.74  LDD0290 
Eukaryotic translation initiation factor 1 (EIF1) LDTP03953 1.63  LDD0290 
Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX) LDTP04129 0.99  LDD0290 
Eukaryotic translation initiation factor 1b (EIF1B) LDTP16815 1.63  LDD0290 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 0.60  LDD0290 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 1.38  LDD0290 
Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 0.95  LDD0290 
Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 0.50  LDD0290 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 0.95  LDD0290 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 1.24  LDD0290 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 0.08  LDD0290 
F-actin-uncapping protein LRRC16A (CARMIL1) LDTP07261 0.90  LDD0290 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 1.81; 0.82; 0.23  LDD0290 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 0.92; 1.26; 0.92 ...  LDD0290 
Gelsolin (GSN) LDTP02145 6.71; 1.23; 1.11 ...  LDD0290 
General transcription factor IIF subunit 2 (GTF2F2) LDTP02703 0.94; 0.87  LDD0290 
Growth factor receptor-bound protein 2 (GRB2) LDTP05035 0.19  LDD0290 
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPVD1) LDTP06255 2.03; 0.96  LDD0290 
Heat shock 70 kDa protein 1A (HSPA1A) LDTP02434 1.68; 1.75; 0.11 ...  LDD0290 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 1.04; 0.93; 3.03 ...  LDD0290 
Heat shock 70 kDa protein 4L (HSPA4L) LDTP14545 0.67  LDD0290 
Heat shock protein 105 kDa (HSPH1) LDTP09811 1.22; 1.18  LDD0290 
Heat shock protein beta-1 (HSPB1) LDTP02053 0.91; 0.89; 0.90 ...  LDD0290 
Heme-binding protein 1 (HEBP1) LDTP16078 0.15; 1.77  LDD0290 
Hepatoma-derived growth factor (HDGF) LDTP04483 1.22  LDD0290 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 1.04; 1.15  LDD0290 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 1.47; 1.04; 1.15 ...  LDD0290 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 1.16; 1.46; 1.34  LDD0290 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 1.37  LDD0290 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 1.39; 1.23; 1.16 ...  LDD0290 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 1.26; 1.21; 0.98 ...  LDD0290 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 1.10; 1.20; 1.08 ...  LDD0290 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 1.01  LDD0290 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 0.21  LDD0290 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 0.67; 1.01; 1.00 ...  LDD0290 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 1.34; 1.34; 1.89 ...  LDD0290 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 0.64  LDD0290 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 1.16; 0.98; 1.01 ...  LDD0290 
Histone H2B type 1-D (H2BC5) LDTP04822 0.36; 0.82; 4.00  LDD0290 
Histone H2B type 1-L (H2BC13) LDTP11001 3.99  LDD0290 
Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) LDTP05004 1.02; 2.15  LDD0290 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 0.35; 0.82  LDD0290 
Hsc70-interacting protein (ST13) LDTP04367 0.07; 0.65; 1.83  LDD0290 
Influenza virus NS1A-binding protein (IVNS1ABP) LDTP14309 1.01  LDD0290 
Integrator complex subunit 10 (INTS10) LDTP16111 1.22  LDD0290 
IST1 homolog (IST1) LDTP04593 1.80  LDD0290 
Kinesin light chain 1 (KLC1) LDTP05533 1.52; 0.39  LDD0290 
Kinesin light chain 2 (KLC2) LDTP11695 1.52; 0.39  LDD0290 
Laminin subunit beta-2 (LAMB2) LDTP04691 2.50  LDD0290 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 1.52  LDD0290 
Large ribosomal subunit protein eL21 (RPL21) LDTP04107 1.05; 0.47; 1.34  LDD0290 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 0.55; 1.16  LDD0290 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 1.67; 5.87  LDD0290 
Large ribosomal subunit protein eL29 (RPL29) LDTP04140 1.32  LDD0290 
Large ribosomal subunit protein eL31 (RPL31) LDTP05023 2.50  LDD0290 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 2.56; 1.04  LDD0290 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 1.30  LDD0290 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 4.87; 1.28  LDD0290 
Large ribosomal subunit protein eL37 (RPL37) LDTP04943 1.45  LDD0290 
Large ribosomal subunit protein eL43 (RPL37A) LDTP04926 1.25  LDD0290 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 0.55  LDD0290 
Large ribosomal subunit protein uL13 (RPL13A) LDTP03899 1.16; 1.09; 0.93  LDD0290 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 0.72  LDD0290 
Large ribosomal subunit protein uL15 (RPL27A) LDTP04105 1.31  LDD0290 
Large ribosomal subunit protein uL18 (RPL5) LDTP04106 0.98  LDD0290 
Large ribosomal subunit protein uL2 (RPL8) LDTP05027 1.02  LDD0290 
Large ribosomal subunit protein uL29 (RPL35) LDTP03999 0.82  LDD0290 
Large ribosomal subunit protein uL30 (RPL7) LDTP02944 0.89  LDD0290 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 0.92; 0.73; 0.88 ...  LDD0290 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 1.60; 1.59  LDD0290 
LIM domain and actin-binding protein 1 (LIMA1) LDTP13260 1.17  LDD0290 
LRP chaperone MESD (MESD) LDTP06191 0.74  LDD0290 
Macrophage-capping protein (CAPG) LDTP03877 0.25; 0.78  LDD0290 
Microtubule-associated protein 4 (MAP4) LDTP03404 1.37; 0.10  LDD0290 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 0.21  LDD0290 
Muscleblind-like protein 1 (MBNL1) LDTP12478 1.57; 1.05  LDD0290 
Muscleblind-like protein 2 (MBNL2) LDTP07260 1.57  LDD0290 
Muscleblind-like protein 3 (MBNL3) LDTP12630 1.05  LDD0290 
Myosin regulatory light chain 12B (MYL12B) LDTP00487 0.40  LDD0290 
N6-adenosine-methyltransferase non-catalytic subunit (METTL14) LDTP12234 1.39  LDD0290 
Nascent polypeptide-associated complex subunit alpha (NACA) LDTP05977 0.07; 0.34  LDD0290 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 1.13; 1.19  LDD0290 
Nuclear migration protein nudC (NUDC) LDTP13817 1.19  LDD0290 
Nucleolin (NCL) LDTP02990 1.04; 1.20; 1.31 ...  LDD0290 
Nucleolysin TIAR (TIAL1) LDTP05274 0.19  LDD0290 
Nucleophosmin (NPM1) LDTP02164 1.05; 1.36  LDD0290 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 0.48; 1.96; 0.97  LDD0290 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 1.12; 0.97  LDD0290 
Perilipin-3 (PLIN3) LDTP01021 0.58  LDD0290 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 0.12; 2.59; 0.09 ...  LDD0290 
Plastin-3 (PLS3) LDTP02692 0.46; 0.94  LDD0290 
Platelet-activating factor acetylhydrolase IB subunit beta (PAFAH1B1) LDTP04015 1.25; 0.14  LDD0290 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 0.65; 1.91; 1.58  LDD0290 
Poly(rC)-binding protein 2 (PCBP2) LDTP06367 1.28; 0.13  LDD0290 
Polyadenylate-binding protein 1 (PABPC1) LDTP02595 0.98; 1.13; 1.10 ...  LDD0290 
Polyadenylate-binding protein 4 (PABPC4) LDTP05821 0.46; 0.99  LDD0290 
Polypyrimidine tract-binding protein 1 (PTBP1) LDTP03364 1.38; 1.14  LDD0290 
Prefoldin subunit 3 (VBP1) LDTP04935 0.26  LDD0290 
Prelamin-A/C (LMNA) LDTP01932 1.12; 0.92  LDD0290 
Profilin-1 (PFN1) LDTP02218 1.30; 1.57  LDD0290 
Programmed cell death protein 5 (PDCD5) LDTP00417 3.02  LDD0290 
Proliferating cell nuclear antigen (PCNA) LDTP02596 0.44  LDD0290 
Protein BUD31 homolog (BUD31) LDTP03935 0.63  LDD0290 
Protein FAM118B (FAM118B) LDTP15852 0.82  LDD0290 
Protein flightless-1 homolog (FLII) LDTP05734 0.05  LDD0290 
Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) LDTP13656 0.62; 1.61; 1.17 ...  LDD0290 
Protein mago nashi homolog 2 (MAGOHB) LDTP10071 1.17  LDD0290 
Protein NipSnap homolog 3A (NIPSNAP3A) LDTP18525 0.21; 0.55  LDD0290 
Protein phosphatase 1 regulatory subunit 12A (PPP1R12A) LDTP00495 0.26  LDD0290 
Protein RCC2 (RCC2) LDTP13020 1.87  LDD0290 
Protein S100-A11 (S100A11) LDTP03620 0.89; 1.62  LDD0290 
Protein SET (SET) LDTP05277 0.33  LDD0290 
Protein SGT1 homolog (SUGT1) LDTP13935 0.10; 1.94  LDD0290 
Protein TFG (TFG) LDTP09851 1.67  LDD0290 
Protein transport protein Sec23A (SEC23A) LDTP06390 0.92  LDD0290 
Protein transport protein Sec23B (SEC23B) LDTP06391 0.70  LDD0290 
Protein UXT (UXT) LDTP13125 0.33  LDD0290 
Putative protein FAM10A5 (ST13P5) LDTP17811 1.83  LDD0290 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 0.97  LDD0290 
Pyridoxal phosphate homeostasis protein (PLPBP) LDTP14521 0.11; 0.10  LDD0290 
Rab GDP dissociation inhibitor alpha (GDI1) LDTP03574 1.18; 2.44  LDD0290 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 1.90; 2.16; 0.05 ...  LDD0290 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 1.26  LDD0290 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 1.54; 1.48; 1.06  LDD0290 
Reticulocalbin-1 (RCN1) LDTP06352 0.31  LDD0290 
Retinoblastoma-associated protein (RB1) LDTP02146 0.18  LDD0290 
Rho GDP-dissociation inhibitor 1 (ARHGDIA) LDTP04510 0.75; 1.81; 0.60 ...  LDD0290 
Rho guanine nucleotide exchange factor 2 (ARHGEF2) LDTP09950 0.73  LDD0290 
Ribosome biogenesis protein WDR12 (WDR12) LDTP11625 0.17  LDD0290 
RNA-binding protein 3 (RBM3) LDTP05226 1.00; 1.01  LDD0290 
RNA-binding protein EWS (EWSR1) LDTP05318 1.14  LDD0290 
RNA-binding protein FUS (FUS) LDTP03775 2.98; 1.31  LDD0290 
Serine/arginine-rich splicing factor 2 (SRSF2) LDTP05280 0.94  LDD0290 
Serine/arginine-rich splicing factor 8 (SRSF8) LDTP11117 0.94  LDD0290 
Single-stranded DNA-binding protein, mitochondrial (SSBP1) LDTP05437 1.23; 0.91; 1.26 ...  LDD0290 
Small acidic protein (SMAP) LDTP19007 1.85  LDD0290 
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) LDTP00862 0.45; 1.27; 1.13 ...  LDD0290 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 1.12; 0.57; 0.90  LDD0290 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 1.16; 1.57  LDD0290 
Small ribosomal subunit protein eS19 (RPS19) LDTP03864 0.97  LDD0290 
Small ribosomal subunit protein eS24 (RPS24) LDTP05012 0.86; 1.47; 0.84  LDD0290 
Small ribosomal subunit protein eS26 (RPS26) LDTP05014 0.34  LDD0290 
Small ribosomal subunit protein eS27 (RPS27) LDTP03987 0.17  LDD0290 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 1.19; 1.22  LDD0290 
Small ribosomal subunit protein eS4, Y isoform 1 (RPS4Y1) LDTP14653 1.22  LDD0290 
Small ribosomal subunit protein eS4, Y isoform 2 (RPS4Y2) LDTP19820 1.22  LDD0290 
Small ribosomal subunit protein eS7 (RPS7) LDTP04958 0.73  LDD0290 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 1.36; 2.47; 1.99 ...  LDD0290 
Small ribosomal subunit protein uS11 (RPS14) LDTP04970 0.87  LDD0290 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 0.58  LDD0290 
Small ribosomal subunit protein uS13 (RPS18) LDTP04972 2.10; 1.81  LDD0290 
Small ribosomal subunit protein uS15 (RPS13) LDTP04974 1.06; 1.31; 1.36  LDD0290 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 0.99; 0.99  LDD0290 
Small ribosomal subunit protein uS2 (RPSA) LDTP02312 2.05  LDD0290 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 1.09; 0.86; 0.80  LDD0290 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 0.91; 0.66  LDD0290 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 0.15; 0.81  LDD0290 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 0.90  LDD0290 
Splicing factor YJU2 (YJU2) LDTP11317 1.42  LDD0290 
Src substrate cortactin (CTTN) LDTP06094 1.22; 0.16; 1.30 ...  LDD0290 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 1.13; 0.69; 0.13 ...  LDD0290 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 0.77; 0.43; 0.80 ...  LDD0290 
Stromal cell-derived factor 2-like protein 1 (SDF2L1) LDTP16047 2.01  LDD0290 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 1.14; 0.24  LDD0290 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 3.77  LDD0290 
Structural maintenance of chromosomes protein 4 (SMC4) LDTP12606 1.03  LDD0290 
T-complex protein 1 subunit beta (CCT2) LDTP05113 1.70; 1.44  LDD0290 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 1.02  LDD0290 
T-complex protein 1 subunit eta (CCT7) LDTP10990 1.39  LDD0290 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 0.74; 0.62  LDD0290 
T-complex protein 1 subunit theta (CCT8) LDTP04390 0.89; 0.64; 0.91 ...  LDD0290 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 1.20  LDD0290 
T-complex protein 1 subunit zeta-2 (CCT6B) LDTP09777 1.20  LDD0290 
Tetratricopeptide repeat protein 1 (TTC1) LDTP15840 0.10  LDD0290 
Tetratricopeptide repeat protein 4 (TTC4) LDTP01678 0.94  LDD0290 
Transcription elongation factor A protein 1 (TCEA1) LDTP03209 2.08  LDD0290 
Transcription elongation factor SPT6 (SUPT6H) LDTP07928 0.31  LDD0290 
Transgelin-2 (TAGLN2) LDTP03846 0.21; 1.61; 1.36  LDD0290 
Translation initiation factor eIF2B subunit delta (EIF2B4) LDTP13318 1.09  LDD0290 
Translationally-controlled tumor protein (TPT1) LDTP02683 2.00; 0.47  LDD0290 
Transmembrane glycoprotein NMB (GPNMB) LDTP06237 2.33  LDD0290 
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WDR6) LDTP12296 0.85  LDD0290 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 1.92  LDD0290 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 2.17  LDD0290 
Tubulin beta chain (TUBB) LDTP02205 0.86; 0.84; 0.88 ...  LDD0290 
Tubulin beta-2A chain (TUBB2A) LDTP05998 1.16; 1.12; 0.94 ...  LDD0290 
Tubulin beta-2B chain (TUBB2B) LDTP11277 0.40; 1.16; 1.12 ...  LDD0290 
Tubulin beta-3 chain (TUBB3) LDTP05904 0.83; 1.16; 0.42 ...  LDD0290 
Tubulin beta-4A chain (TUBB4A) LDTP02037 0.93; 0.95; 1.01 ...  LDD0290 
Tubulin beta-4B chain (TUBB4B) LDTP05076 0.55; 1.09; 0.63 ...  LDD0290 
Tubulin beta-6 chain (TUBB6) LDTP11233 1.20; 1.23; 1.06  LDD0290 
Tubulin gamma-1 chain (TUBG1) LDTP03213 2.75  LDD0290 
Tubulin gamma-2 chain (TUBG2) LDTP12512 2.75  LDD0290 
Tubulin-folding cofactor B (TBCB) LDTP10860 1.88; 1.34  LDD0290 
U6 snRNA-associated Sm-like protein LSm2 (LSM2) LDTP13946 0.16  LDD0290 
Ubiquilin-1 (UBQLN1) LDTP13626 1.04  LDD0290 
Ubiquitin-associated protein 2-like (UBAP2L) LDTP06060 0.88  LDD0290 
Ubiquitin-fold modifier 1 (UFM1) LDTP04946 2.34  LDD0290 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 1.33  LDD0290 
Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) LDTP11534 0.82  LDD0290 
Vacuolar fusion protein CCZ1 homolog (CCZ1) LDTP14797 0.59  LDD0290 
Vacuolar protein sorting-associated protein VTA1 homolog (VTA1) LDTP12317 20.00  LDD0290 
Vasodilator-stimulated phosphoprotein (VASP) LDTP04372 1.61  LDD0290 
Vimentin (VIM) LDTP02297 0.86; 0.97; 0.05 ...  LDD0290 
Vinculin (VCL) LDTP02946 0.18; 2.18  LDD0290 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 1.28  LDD0290 
WD repeat-containing protein 1 (WDR1) LDTP01118 1.72; 2.50; 0.98 ...  LDD0290 
WW domain-binding protein 2 (WBP2) LDTP10033 1.22; 1.88; 2.23  LDD0290 
Zyxin (ZYX) LDTP06507 0.39; 1.55  LDD0290 
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Full Information of The Labelling Profiles of This Competitor

HHS-482

Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 50 uM
Quantitative Method SILAC
Competitor Name JWB198
Competitor Concentration 50 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Skin
Disease Model Melanoma [ICD-11:2C82]
Model Name Human melanoma cell lysate (DM93)
Interaction Atlas ID  LDD0290  Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 50 uM
Quantitative Method SILAC
Competitor Name JWB198
Competitor Concentration 50 uM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Skin
Disease Model Melanoma [ICD-11:2C82]
Model Name Human melanoma cells (DM93)
Interaction Atlas ID  LDD0295  Download The Altas

References

1 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.