General Information of Target

Target ID LDTP02008
Target Name Fructose-bisphosphate aldolase A (ALDOA)
Gene Name ALDOA
Gene ID 226
Synonyms
ALDA; Fructose-bisphosphate aldolase A; EC 4.1.2.13; Lung cancer antigen NY-LU-1; Muscle-type aldolase
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYR
QLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTN
GETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQ
NGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHAC
TQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTF
SYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFVS
NHAY
Target Bioclass
Enzyme
Family
Class I fructose-bisphosphate aldolase family
Subcellular location
Cytoplasm, myofibril, sarcomere, I band
Function
Catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein.
Uniprot ID
P04075
Ensemble ID
ENST00000412304.6
HGNC ID
HGNC:414
ChEMBL ID
CHEMBL2106

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 66 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
Alkylaryl probe 1
 Probe Info 
16.00  LDD0385  [1]
Alkylaryl probe 2
 Probe Info 
12.00  LDD0389  [1]
P1
 Probe Info 
3.09  LDD0452  [2]
P2
 Probe Info 
2.64  LDD0453  [2]
P3
 Probe Info 
1.58  LDD0450  [2]
P8
 Probe Info 
1.68  LDD0451  [2]
A-EBA
 Probe Info 
4.52  LDD0215  [3]
8RK64
 Probe Info 
N.A.  LDD0039  [4]
CY-1
 Probe Info 
7.38  LDD0243  [5]
CY4
 Probe Info 
3.39  LDD0244  [5]
N1
 Probe Info 
4.15  LDD0242  [5]
TH211
 Probe Info 
Y174(16.88); Y328(16.68)  LDD0257  [6]
TH214
 Probe Info 
Y328(12.72); Y302(11.12)  LDD0258  [6]
TH216
 Probe Info 
Y138(20.00); Y328(19.91); Y174(11.72); Y204(10.63)  LDD0259  [6]
YN-4
 Probe Info 
4.85  LDD0445  [7]
AZ-9
 Probe Info 
E50(1.02)  LDD2208  [8]
ONAyne
 Probe Info 
K330(0.00); K14(0.00); K140(0.00); K42(0.00)  LDD0273  [9]
OPA-S-S-alkyne
 Probe Info 
K140(1.69); K330(2.76); K42(3.00); K147(3.40)  LDD3494  [10]
Probe 1
 Probe Info 
Y138(71.21); Y174(15.93); Y214(48.45); Y328(142.06)  LDD3495  [11]
m-APA
 Probe Info 
12.09  LDD0403  [12]
DBIA
 Probe Info 
C393(2.31)  LDD3311  [13]
JZ128-DTB
 Probe Info 
C290(0.00); C339(0.00); C178(0.00)  LDD0462  [14]
THZ1-DTB
 Probe Info 
C178(1.14); C339(1.09); C290(1.05); C73(1.02)  LDD0460  [14]
AHL-Pu-1
 Probe Info 
C73(10.39); C240(20.00); C202(3.45); C178(4.28)  LDD0170  [15]
HHS-482
 Probe Info 
Y138(1.17); Y174(2.09); Y204(1.10); Y214(0.68)  LDD0285  [16]
HHS-475
 Probe Info 
Y328(0.90); Y204(1.02); Y138(1.22)  LDD0264  [17]
HHS-465
 Probe Info 
Y138(10.00); Y204(10.00); Y302(2.31); Y328(6.04)  LDD2237  [18]
5E-2FA
 Probe Info 
H238(0.00); H221(0.00); H21(0.00); H246(0.00)  LDD2235  [19]
AMP probe
 Probe Info 
K42(0.00); K13(0.00); K14(0.00)  LDD0200  [20]
ATP probe
 Probe Info 
K42(0.00); K13(0.00); K14(0.00); K342(0.00)  LDD0199  [20]
4-Iodoacetamidophenylacetylene
 Probe Info 
C339(0.00); C240(0.00); C290(0.00); C202(0.00)  LDD0038  [21]
IA-alkyne
 Probe Info 
C202(0.00); C73(0.00); C339(0.00); C240(0.00)  LDD0032  [22]
IPIAA_H
 Probe Info 
C73(0.00); C202(0.00); C339(0.00); C240(0.00)  LDD0030  [23]
IPIAA_L
 Probe Info 
C240(0.00); C73(0.00); C202(0.00); C290(0.00)  LDD0031  [23]
Lodoacetamide azide
 Probe Info 
C339(0.00); C240(0.00); C290(0.00); C202(0.00)  LDD0037  [21]
ATP probe
 Probe Info 
K140(0.00); K28(0.00); K294(0.00); K330(0.00)  LDD0035  [24]
BTD
 Probe Info 
N.A.  LDD0004  [25]
IPM
 Probe Info 
C339(0.00); C178(0.00)  LDD0025  [26]
JW-RF-010
 Probe Info 
N.A.  LDD0026  [26]
NAIA_4
 Probe Info 
C178(0.00); C339(0.00)  LDD2226  [27]
TFBX
 Probe Info 
N.A.  LDD0027  [26]
WYneC
 Probe Info 
N.A.  LDD0014  [25]
WYneN
 Probe Info 
C339(0.00); C178(0.00)  LDD0021  [25]
WYneO
 Probe Info 
N.A.  LDD0022  [25]
KY-26
 Probe Info 
N.A.  LDD0301  [28]
1d-yne
 Probe Info 
K111(0.00); K108(0.00)  LDD0356  [29]
Compound 10
 Probe Info 
C178(0.00); C202(0.00); C290(0.00); C339(0.00)  LDD2216  [30]
Compound 11
 Probe Info 
C290(0.00); C339(0.00); C73(0.00)  LDD2213  [30]
ENE
 Probe Info 
N.A.  LDD0006  [25]
NHS
 Probe Info 
K322(0.00); K111(0.00); K99(0.00); K312(0.00)  LDD0010  [25]
OSF
 Probe Info 
Y3(0.00); H21(0.00); H246(0.00)  LDD0029  [31]
PF-06672131
 Probe Info 
N.A.  LDD0017  [32]
SF
 Probe Info 
K99(0.00); K28(0.00); K322(0.00); K111(0.00)  LDD0028  [31]
STPyne
 Probe Info 
K312(0.00); K42(0.00); K111(0.00)  LDD0009  [25]
VSF
 Probe Info 
N.A.  LDD0007  [25]
Ox-W18
 Probe Info 
N.A.  LDD2175  [33]
1c-yne
 Probe Info 
K111(0.00); K108(0.00); K153(0.00); K322(0.00)  LDD0228  [29]
Acrolein
 Probe Info 
H362(0.00); C240(0.00); C73(0.00); H157(0.00)  LDD0217  [34]
Cinnamaldehyde
 Probe Info 
N.A.  LDD0220  [34]
Crotonaldehyde
 Probe Info 
C339(0.00); H157(0.00); H21(0.00); H362(0.00)  LDD0219  [34]
Methacrolein
 Probe Info 
H362(0.00); C240(0.00); C339(0.00); H246(0.00)  LDD0218  [34]
W1
 Probe Info 
N.A.  LDD0236  [35]
MPP-AC
 Probe Info 
N.A.  LDD0428  [36]
NAIA_5
 Probe Info 
C339(0.00); C240(0.00); C290(0.00)  LDD2223  [27]
TER-AC
 Probe Info 
N.A.  LDD0426  [36]
TPP-AC
 Probe Info 
N.A.  LDD0427  [36]
PAL-AfBPP Probe
Click To Hide/Show 5 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C193
 Probe Info 
5.54  LDD1869  [37]
STS-2
 Probe Info 
N.A.  LDD0138  [38]
VE-P
 Probe Info 
N.A.  LDD0396  [39]
Staurosporine capture compound
 Probe Info 
2.00  LDD0083  [40]
STS-1
 Probe Info 
N.A.  LDD0069  [41]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C73(10.39); C240(20.00); C202(3.45); C178(4.28)  LDD0170  [15]
 LDCM0026  4SU-RNA+native RNA HEK-293T C73(19.80)  LDD0372  [15]
 LDCM0214  AC1 HEK-293T C240(0.81); C339(0.92); C73(0.90); C290(1.02)  LDD1507  [42]
 LDCM0215  AC10 HEK-293T C240(0.88); C339(1.00); C73(0.86); C290(0.97)  LDD1508  [42]
 LDCM0226  AC11 HEK-293T C240(0.86); C339(0.90); C73(0.85); C290(1.01)  LDD1509  [42]
 LDCM0237  AC12 HEK-293T C240(0.81); C339(0.95); C73(0.90); C290(0.92)  LDD1510  [42]
 LDCM0259  AC14 HEK-293T C240(0.83); C339(1.04); C73(1.16); C290(0.99)  LDD1512  [42]
 LDCM0270  AC15 HEK-293T C240(0.87); C339(0.91); C73(0.87); C290(0.99)  LDD1513  [42]
 LDCM0276  AC17 HEK-293T C240(0.73); C339(0.90); C73(0.94); C290(1.13)  LDD1515  [42]
 LDCM0277  AC18 HEK-293T C240(0.87); C339(1.00); C73(0.85); C290(0.83)  LDD1516  [42]
 LDCM0278  AC19 HEK-293T C240(0.76); C339(0.81); C73(0.76); C290(0.96)  LDD1517  [42]
 LDCM0279  AC2 HEK-293T C240(0.94); C339(1.01); C73(1.07); C290(1.01)  LDD1518  [42]
 LDCM0280  AC20 HEK-293T C240(0.83); C339(1.00); C73(0.96); C290(0.94)  LDD1519  [42]
 LDCM0281  AC21 HEK-293T C240(0.97); C339(1.10); C73(0.97); C290(1.08)  LDD1520  [42]
 LDCM0282  AC22 HEK-293T C240(0.85); C339(1.09); C73(1.12); C290(1.00)  LDD1521  [42]
 LDCM0283  AC23 HEK-293T C240(0.87); C339(0.98); C73(0.97); C290(1.09)  LDD1522  [42]
 LDCM0284  AC24 HEK-293T C240(0.92); C339(1.04); C73(1.01); C290(1.06)  LDD1523  [42]
 LDCM0285  AC25 HEK-293T C240(0.80); C339(0.87); C73(0.82); C290(1.12)  LDD1524  [42]
 LDCM0286  AC26 HEK-293T C240(0.86); C339(1.03); C73(0.84); C290(0.91)  LDD1525  [42]
 LDCM0287  AC27 HEK-293T C240(0.83); C339(0.96); C73(0.92); C290(1.00)  LDD1526  [42]
 LDCM0288  AC28 HEK-293T C240(0.87); C339(0.98); C73(0.98); C290(0.91)  LDD1527  [42]
 LDCM0289  AC29 HEK-293T C240(0.97); C339(1.12); C73(1.09); C290(1.04)  LDD1528  [42]
 LDCM0290  AC3 HEK-293T C240(0.86); C339(0.95); C73(0.91); C290(0.91)  LDD1529  [42]
 LDCM0291  AC30 HEK-293T C240(0.91); C339(1.15); C73(1.07); C290(1.02)  LDD1530  [42]
 LDCM0292  AC31 HEK-293T C240(0.89); C339(0.96); C73(0.93); C290(0.98)  LDD1531  [42]
 LDCM0293  AC32 HEK-293T C240(0.94); C339(1.00); C73(0.96); C290(0.91)  LDD1532  [42]
 LDCM0294  AC33 HEK-293T C240(0.73); C339(0.79); C73(0.93); C290(1.08)  LDD1533  [42]
 LDCM0295  AC34 HEK-293T C240(0.82); C339(0.92); C73(0.94); C290(0.97)  LDD1534  [42]
 LDCM0296  AC35 HEK-293T C240(0.77); C339(0.86); C73(1.02); C290(0.98)  LDD1535  [42]
 LDCM0297  AC36 HEK-293T C240(0.79); C339(1.00); C73(0.97); C290(0.98)  LDD1536  [42]
 LDCM0298  AC37 HEK-293T C240(1.02); C339(1.06); C73(1.16); C290(1.09)  LDD1537  [42]
 LDCM0299  AC38 HEK-293T C240(0.82); C339(1.06); C73(1.13); C290(0.98)  LDD1538  [42]
 LDCM0300  AC39 HEK-293T C240(0.87); C339(0.86); C73(0.93); C290(0.94)  LDD1539  [42]
 LDCM0301  AC4 HEK-293T C240(0.89); C339(1.07); C73(1.01); C290(1.00)  LDD1540  [42]
 LDCM0302  AC40 HEK-293T C240(0.89); C339(0.99); C73(1.01); C290(0.96)  LDD1541  [42]
 LDCM0303  AC41 HEK-293T C240(0.73); C339(0.87); C73(0.84); C290(1.06)  LDD1542  [42]
 LDCM0304  AC42 HEK-293T C240(0.84); C339(0.93); C73(0.89); C290(0.98)  LDD1543  [42]
 LDCM0305  AC43 HEK-293T C240(0.80); C339(0.84); C73(0.96); C290(1.01)  LDD1544  [42]
 LDCM0306  AC44 HEK-293T C240(0.82); C339(1.01); C73(0.91); C290(0.86)  LDD1545  [42]
 LDCM0307  AC45 HEK-293T C240(0.93); C339(0.97); C73(1.02); C290(0.97)  LDD1546  [42]
 LDCM0308  AC46 HEK-293T C240(0.83); C339(1.01); C73(1.21); C290(0.98)  LDD1547  [42]
 LDCM0309  AC47 HEK-293T C240(0.88); C339(0.87); C73(0.86); C290(0.89)  LDD1548  [42]
 LDCM0310  AC48 HEK-293T C240(0.93); C339(1.02); C73(0.98); C290(1.01)  LDD1549  [42]
 LDCM0311  AC49 HEK-293T C240(0.80); C339(0.82); C73(0.79); C290(1.03)  LDD1550  [42]
 LDCM0312  AC5 HEK-293T C240(1.03); C339(1.05); C73(1.00); C290(1.02)  LDD1551  [42]
 LDCM0313  AC50 HEK-293T C240(0.91); C339(1.03); C73(0.89); C290(0.99)  LDD1552  [42]
 LDCM0314  AC51 HEK-293T C240(0.92); C339(0.92); C73(0.97); C290(1.08)  LDD1553  [42]
 LDCM0315  AC52 HEK-293T C240(0.87); C339(0.97); C73(0.88); C290(0.93)  LDD1554  [42]
 LDCM0316  AC53 HEK-293T C240(1.01); C339(0.92); C73(0.93); C290(0.99)  LDD1555  [42]
 LDCM0317  AC54 HEK-293T C240(0.89); C339(0.98); C73(1.02); C290(0.95)  LDD1556  [42]
 LDCM0318  AC55 HEK-293T C240(0.91); C339(0.87); C73(0.83); C290(0.98)  LDD1557  [42]
 LDCM0319  AC56 HEK-293T C240(0.91); C339(1.01); C73(0.87); C290(0.92)  LDD1558  [42]
 LDCM0320  AC57 HEK-293T C240(0.69); C339(0.78); C73(0.72); C290(0.98)  LDD1559  [42]
 LDCM0321  AC58 HEK-293T C240(0.84); C339(1.02); C73(0.87); C290(0.88)  LDD1560  [42]
 LDCM0322  AC59 HEK-293T C240(0.82); C339(0.98); C73(0.98); C290(0.94)  LDD1561  [42]
 LDCM0323  AC6 HEK-293T C240(0.97); C339(1.08); C73(1.07); C290(0.95)  LDD1562  [42]
 LDCM0324  AC60 HEK-293T C240(0.74); C339(0.98); C73(0.98); C290(0.88)  LDD1563  [42]
 LDCM0325  AC61 HEK-293T C240(0.88); C339(0.98); C73(0.90); C290(1.02)  LDD1564  [42]
 LDCM0326  AC62 HEK-293T C240(0.80); C339(0.98); C73(0.94); C290(0.92)  LDD1565  [42]
 LDCM0327  AC63 HEK-293T C240(0.80); C339(0.89); C73(0.96); C290(0.96)  LDD1566  [42]
 LDCM0328  AC64 HEK-293T C240(0.93); C339(1.10); C73(0.95); C290(0.92)  LDD1567  [42]
 LDCM0334  AC7 HEK-293T C240(0.97); C339(0.96); C73(0.97); C290(0.97)  LDD1568  [42]
 LDCM0345  AC8 HEK-293T C240(1.00); C339(1.06); C73(0.95); C290(1.03)  LDD1569  [42]
 LDCM0248  AKOS034007472 HEK-293T C240(1.02); C339(0.98); C73(0.91); C290(1.00)  LDD1511  [42]
 LDCM0356  AKOS034007680 HEK-293T C240(0.77); C339(0.83); C73(0.85); C290(1.12)  LDD1570  [42]
 LDCM0275  AKOS034007705 HEK-293T C240(0.92); C339(1.06); C73(0.87); C290(0.95)  LDD1514  [42]
 LDCM0156  Aniline NCI-H1299 12.09  LDD0403  [12]
 LDCM0630  CCW28-3 231MFP C339(2.12)  LDD2214  [43]
 LDCM0108  Chloroacetamide HeLa C240(0.00); H362(0.00); C73(0.00); H157(0.00)  LDD0222  [34]
 LDCM0632  CL-Sc Hep-G2 C339(2.39); C202(1.80); C290(1.23); C339(1.00)  LDD2227  [27]
 LDCM0367  CL1 HEK-293T C240(0.77); C339(0.94); C73(0.91); C290(1.01)  LDD1571  [42]
 LDCM0368  CL10 HEK-293T C240(1.06); C339(0.75); C73(1.30); C290(0.39)  LDD1572  [42]
 LDCM0369  CL100 HEK-293T C240(0.85); C339(0.89); C73(0.94); C290(1.01)  LDD1573  [42]
 LDCM0370  CL101 HEK-293T C240(0.82); C339(0.92); C73(0.81); C290(0.99)  LDD1574  [42]
 LDCM0371  CL102 HEK-293T C240(0.80); C339(0.90); C73(0.89); C290(1.01)  LDD1575  [42]
 LDCM0372  CL103 HEK-293T C240(0.81); C339(0.89); C73(0.91); C290(1.11)  LDD1576  [42]
 LDCM0373  CL104 HEK-293T C240(0.94); C339(0.95); C73(0.80); C290(1.09)  LDD1577  [42]
 LDCM0374  CL105 HEK-293T C240(0.81); C339(0.95); C73(1.01); C290(1.22)  LDD1578  [42]
 LDCM0375  CL106 HEK-293T C240(0.89); C339(1.02); C73(0.96); C290(0.89)  LDD1579  [42]
 LDCM0376  CL107 HEK-293T C240(0.84); C339(1.10); C73(0.91); C290(1.13)  LDD1580  [42]
 LDCM0377  CL108 HEK-293T C240(0.86); C339(0.94); C73(0.83); C290(1.07)  LDD1581  [42]
 LDCM0378  CL109 HEK-293T C240(0.79); C339(1.03); C73(0.96); C290(1.04)  LDD1582  [42]
 LDCM0379  CL11 HEK-293T C240(1.08); C339(0.96); C73(0.94); C290(0.36)  LDD1583  [42]
 LDCM0380  CL110 HEK-293T C240(0.78); C339(0.92); C73(0.91); C290(0.71)  LDD1584  [42]
 LDCM0381  CL111 HEK-293T C240(0.83); C339(0.96); C73(0.98); C290(1.02)  LDD1585  [42]
 LDCM0382  CL112 HEK-293T C240(0.89); C339(0.86); C73(0.91); C290(1.04)  LDD1586  [42]
 LDCM0383  CL113 HEK-293T C240(0.78); C339(0.88); C73(1.04); C290(1.07)  LDD1587  [42]
 LDCM0384  CL114 HEK-293T C240(0.76); C339(0.86); C73(0.87); C290(1.00)  LDD1588  [42]
 LDCM0385  CL115 HEK-293T C240(0.89); C339(0.97); C73(1.01); C290(1.07)  LDD1589  [42]
 LDCM0386  CL116 HEK-293T C240(0.81); C339(0.92); C73(0.95); C290(1.19)  LDD1590  [42]
 LDCM0387  CL117 HEK-293T C240(0.81); C339(0.90); C73(0.98); C290(0.94)  LDD1591  [42]
 LDCM0388  CL118 HEK-293T C240(0.87); C339(0.95); C73(0.81); C290(1.03)  LDD1592  [42]
 LDCM0389  CL119 HEK-293T C240(0.90); C339(1.04); C73(0.98); C290(1.07)  LDD1593  [42]
 LDCM0390  CL12 HEK-293T C240(0.87); C339(0.87); C73(0.98); C290(0.31)  LDD1594  [42]
 LDCM0391  CL120 HEK-293T C240(0.85); C339(0.90); C73(1.01); C290(1.16)  LDD1595  [42]
 LDCM0392  CL121 HEK-293T C240(0.83); C339(0.92); C73(0.77); C290(1.08)  LDD1596  [42]
 LDCM0393  CL122 HEK-293T C240(0.87); C339(0.92); C73(0.80); C290(0.87)  LDD1597  [42]
 LDCM0394  CL123 HEK-293T C240(0.83); C339(0.87); C73(0.82); C290(1.02)  LDD1598  [42]
 LDCM0395  CL124 HEK-293T C240(0.91); C339(0.92); C73(0.73); C290(1.10)  LDD1599  [42]
 LDCM0396  CL125 HEK-293T C240(0.83); C339(1.05); C73(0.65); C290(1.08)  LDD1600  [42]
 LDCM0397  CL126 HEK-293T C240(0.77); C339(0.94); C73(0.72); C290(0.79)  LDD1601  [42]
 LDCM0398  CL127 HEK-293T C240(0.84); C339(1.02); C73(0.87); C290(0.92)  LDD1602  [42]
 LDCM0399  CL128 HEK-293T C240(0.83); C339(0.96); C73(0.73); C290(1.04)  LDD1603  [42]
 LDCM0400  CL13 HEK-293T C240(0.84); C339(0.84); C73(0.66); C290(0.92)  LDD1604  [42]
 LDCM0401  CL14 HEK-293T C240(0.90); C339(0.90); C73(0.85); C290(0.60)  LDD1605  [42]
 LDCM0402  CL15 HEK-293T C240(0.83); C339(0.79); C73(0.73); C290(0.87)  LDD1606  [42]
 LDCM0403  CL16 HEK-293T C240(0.94); C339(0.87); C73(0.84); C290(1.01)  LDD1607  [42]
 LDCM0404  CL17 HEK-293T C240(0.75); C339(0.73); C73(0.75); C290(0.89)  LDD1608  [42]
 LDCM0405  CL18 HEK-293T C240(0.92); C339(0.96); C73(0.79); C290(0.73)  LDD1609  [42]
 LDCM0406  CL19 HEK-293T C240(1.04); C339(0.86); C73(0.88); C290(0.78)  LDD1610  [42]
 LDCM0407  CL2 HEK-293T C240(0.83); C339(0.97); C73(0.87); C290(0.82)  LDD1611  [42]
 LDCM0408  CL20 HEK-293T C240(1.13); C339(1.08); C73(1.04); C290(0.56)  LDD1612  [42]
 LDCM0409  CL21 HEK-293T C240(1.03); C339(0.80); C73(0.77); C290(0.37)  LDD1613  [42]
 LDCM0410  CL22 HEK-293T C240(1.42); C339(1.04); C73(1.36); C290(0.43)  LDD1614  [42]
 LDCM0411  CL23 HEK-293T C240(1.29); C339(0.90); C73(0.94); C290(0.35)  LDD1615  [42]
 LDCM0412  CL24 HEK-293T C240(1.05); C339(0.99); C73(0.93); C290(0.30)  LDD1616  [42]
 LDCM0413  CL25 HEK-293T C240(0.74); C339(0.90); C73(0.74); C290(0.87)  LDD1617  [42]
 LDCM0414  CL26 HEK-293T C240(0.86); C339(0.95); C73(0.87); C290(0.85)  LDD1618  [42]
 LDCM0415  CL27 HEK-293T C240(0.92); C339(0.98); C73(0.91); C290(1.04)  LDD1619  [42]
 LDCM0416  CL28 HEK-293T C240(0.89); C339(0.90); C73(0.88); C290(1.00)  LDD1620  [42]
 LDCM0417  CL29 HEK-293T C240(0.83); C339(0.88); C73(0.93); C290(0.96)  LDD1621  [42]
 LDCM0418  CL3 HEK-293T C240(0.86); C339(1.02); C73(0.82); C290(0.97)  LDD1622  [42]
 LDCM0419  CL30 HEK-293T C240(0.95); C339(1.08); C73(0.89); C290(0.72)  LDD1623  [42]
 LDCM0420  CL31 HEK-293T C240(0.97); C339(0.90); C73(0.81); C290(0.64)  LDD1624  [42]
 LDCM0421  CL32 HEK-293T C240(1.14); C339(1.01); C73(0.96); C290(0.54)  LDD1625  [42]
 LDCM0422  CL33 HEK-293T C240(0.93); C339(0.84); C73(0.68); C290(0.37)  LDD1626  [42]
 LDCM0423  CL34 HEK-293T C240(1.28); C339(1.01); C73(1.20); C290(0.41)  LDD1627  [42]
 LDCM0424  CL35 HEK-293T C240(1.22); C339(0.89); C73(0.92); C290(0.27)  LDD1628  [42]
 LDCM0425  CL36 HEK-293T C240(0.97); C339(1.00); C73(0.92); C290(0.27)  LDD1629  [42]
 LDCM0426  CL37 HEK-293T C240(0.84); C339(0.94); C73(0.85); C290(0.89)  LDD1630  [42]
 LDCM0428  CL39 HEK-293T C240(0.85); C339(0.88); C73(1.04); C290(0.97)  LDD1632  [42]
 LDCM0429  CL4 HEK-293T C240(0.84); C339(0.87); C73(0.63); C290(0.85)  LDD1633  [42]
 LDCM0430  CL40 HEK-293T C240(0.91); C339(0.93); C73(1.00); C290(1.03)  LDD1634  [42]
 LDCM0431  CL41 HEK-293T C240(0.76); C339(0.86); C73(0.91); C290(0.91)  LDD1635  [42]
 LDCM0432  CL42 HEK-293T C240(0.98); C339(1.05); C73(0.82); C290(0.56)  LDD1636  [42]
 LDCM0433  CL43 HEK-293T C240(1.08); C339(1.11); C73(1.01); C290(0.65)  LDD1637  [42]
 LDCM0434  CL44 HEK-293T C240(1.01); C339(0.97); C73(1.07); C290(0.61)  LDD1638  [42]
 LDCM0435  CL45 HEK-293T C240(0.97); C339(0.92); C73(0.84); C290(0.53)  LDD1639  [42]
 LDCM0436  CL46 HEK-293T C240(1.30); C339(1.04); C73(1.36); C290(0.44)  LDD1640  [42]
 LDCM0437  CL47 HEK-293T C240(1.21); C339(0.93); C73(0.89); C290(0.29)  LDD1641  [42]
 LDCM0438  CL48 HEK-293T C240(0.98); C339(0.92); C73(0.87); C290(0.23)  LDD1642  [42]
 LDCM0439  CL49 HEK-293T C240(0.81); C339(1.01); C73(0.72); C290(0.86)  LDD1643  [42]
 LDCM0440  CL5 HEK-293T C240(0.84); C339(0.88); C73(0.75); C290(0.92)  LDD1644  [42]
 LDCM0441  CL50 HEK-293T C240(0.78); C339(0.84); C73(0.81); C290(0.85)  LDD1645  [42]
 LDCM0443  CL52 HEK-293T C240(0.89); C339(0.93); C73(0.86); C290(1.05)  LDD1646  [42]
 LDCM0444  CL53 HEK-293T C240(0.68); C339(0.78); C73(0.82); C290(0.83)  LDD1647  [42]
 LDCM0445  CL54 HEK-293T C240(0.75); C339(0.90); C73(0.71); C290(0.75)  LDD1648  [42]
 LDCM0446  CL55 HEK-293T C240(0.92); C339(0.94); C73(1.02); C290(0.60)  LDD1649  [42]
 LDCM0447  CL56 HEK-293T C240(1.01); C339(0.99); C73(1.07); C290(0.52)  LDD1650  [42]
 LDCM0448  CL57 HEK-293T C240(0.99); C339(0.85); C73(0.84); C290(0.48)  LDD1651  [42]
 LDCM0449  CL58 HEK-293T C240(1.28); C339(0.95); C73(1.32); C290(0.40)  LDD1652  [42]
 LDCM0450  CL59 HEK-293T C240(1.09); C339(0.87); C73(0.79); C290(0.32)  LDD1653  [42]
 LDCM0451  CL6 HEK-293T C240(0.78); C339(0.85); C73(0.65); C290(0.59)  LDD1654  [42]
 LDCM0452  CL60 HEK-293T C240(0.96); C339(0.89); C73(0.98); C290(0.27)  LDD1655  [42]
 LDCM0453  CL61 HEK-293T C240(0.79); C339(0.93); C73(0.89); C290(0.89)  LDD1656  [42]
 LDCM0454  CL62 HEK-293T C240(0.84); C339(0.91); C73(0.94); C290(0.78)  LDD1657  [42]
 LDCM0455  CL63 HEK-293T C240(0.85); C339(0.94); C73(0.95); C290(1.04)  LDD1658  [42]
 LDCM0456  CL64 HEK-293T C240(0.75); C339(0.89); C73(0.85); C290(0.99)  LDD1659  [42]
 LDCM0457  CL65 HEK-293T C240(0.75); C339(0.88); C73(0.89); C290(0.92)  LDD1660  [42]
 LDCM0458  CL66 HEK-293T C240(0.81); C339(0.92); C73(0.79); C290(0.72)  LDD1661  [42]
 LDCM0459  CL67 HEK-293T C240(0.89); C339(0.93); C73(0.93); C290(0.73)  LDD1662  [42]
 LDCM0460  CL68 HEK-293T C240(1.03); C339(1.02); C73(0.98); C290(0.55)  LDD1663  [42]
 LDCM0461  CL69 HEK-293T C240(1.05); C339(0.99); C73(0.85); C290(0.46)  LDD1664  [42]
 LDCM0462  CL7 HEK-293T C240(0.93); C339(0.90); C73(0.84); C290(0.69)  LDD1665  [42]
 LDCM0463  CL70 HEK-293T C240(1.18); C339(0.94); C73(1.36); C290(0.50)  LDD1666  [42]
 LDCM0464  CL71 HEK-293T C240(1.03); C339(0.85); C73(0.88); C290(0.43)  LDD1667  [42]
 LDCM0465  CL72 HEK-293T C240(0.91); C339(0.85); C73(0.85); C290(0.38)  LDD1668  [42]
 LDCM0466  CL73 HEK-293T C240(0.79); C339(0.94); C73(0.77); C290(0.99)  LDD1669  [42]
 LDCM0467  CL74 HEK-293T C240(0.89); C339(1.03); C73(0.82); C290(0.99)  LDD1670  [42]
 LDCM0469  CL76 HEK-293T C240(0.89); C339(0.99); C73(0.82); C290(1.05)  LDD1672  [42]
 LDCM0470  CL77 HEK-293T C240(0.72); C339(0.78); C73(0.65); C290(0.92)  LDD1673  [42]
 LDCM0471  CL78 HEK-293T C240(0.91); C339(1.05); C73(0.86); C290(0.87)  LDD1674  [42]
 LDCM0472  CL79 HEK-293T C240(0.97); C339(1.08); C73(0.95); C290(0.88)  LDD1675  [42]
 LDCM0473  CL8 HEK-293T C240(0.70); C339(0.73); C73(0.72); C290(0.40)  LDD1676  [42]
 LDCM0474  CL80 HEK-293T C240(1.12); C339(1.20); C73(1.02); C290(0.74)  LDD1677  [42]
 LDCM0475  CL81 HEK-293T C240(1.12); C339(0.97); C73(0.84); C290(0.63)  LDD1678  [42]
 LDCM0476  CL82 HEK-293T C240(1.24); C339(1.23); C73(1.31); C290(0.64)  LDD1679  [42]
 LDCM0477  CL83 HEK-293T C240(1.10); C339(0.95); C73(0.92); C290(0.51)  LDD1680  [42]
 LDCM0478  CL84 HEK-293T C240(0.90); C339(1.00); C73(0.85); C290(0.46)  LDD1681  [42]
 LDCM0479  CL85 HEK-293T C240(0.84); C339(0.93); C73(0.73); C290(1.02)  LDD1682  [42]
 LDCM0480  CL86 HEK-293T C240(0.89); C339(0.90); C73(0.72); C290(0.84)  LDD1683  [42]
 LDCM0481  CL87 HEK-293T C240(0.90); C339(0.92); C73(0.81); C290(0.88)  LDD1684  [42]
 LDCM0482  CL88 HEK-293T C240(0.90); C339(0.88); C73(0.70); C290(1.05)  LDD1685  [42]
 LDCM0483  CL89 HEK-293T C240(0.81); C339(0.87); C73(0.64); C290(0.94)  LDD1686  [42]
 LDCM0484  CL9 HEK-293T C240(1.13); C339(0.93); C73(0.89); C290(0.45)  LDD1687  [42]
 LDCM0485  CL90 HEK-293T C240(0.71); C339(0.79); C73(0.57); C290(0.65)  LDD1688  [42]
 LDCM0486  CL91 HEK-293T C240(1.01); C339(0.98); C73(0.78); C290(0.77)  LDD1689  [42]
 LDCM0487  CL92 HEK-293T C240(0.85); C339(0.88); C73(0.85); C290(0.64)  LDD1690  [42]
 LDCM0488  CL93 HEK-293T C240(1.00); C339(0.91); C73(0.86); C290(0.61)  LDD1691  [42]
 LDCM0489  CL94 HEK-293T C240(1.08); C339(0.94); C73(1.13); C290(0.66)  LDD1692  [42]
 LDCM0490  CL95 HEK-293T C240(0.81); C339(0.66); C73(0.81); C290(0.54)  LDD1693  [42]
 LDCM0491  CL96 HEK-293T C240(0.90); C339(0.94); C73(0.74); C290(0.61)  LDD1694  [42]
 LDCM0492  CL97 HEK-293T C240(0.80); C339(0.96); C73(0.82); C290(0.88)  LDD1695  [42]
 LDCM0493  CL98 HEK-293T C240(0.83); C339(0.97); C73(0.89); C290(1.20)  LDD1696  [42]
 LDCM0494  CL99 HEK-293T C240(0.96); C339(1.08); C73(0.94); C290(0.91)  LDD1697  [42]
 LDCM0495  E2913 HEK-293T C240(0.79); C339(0.81); C73(0.97); C290(0.99)  LDD1698  [42]
 LDCM0625  F8 Ramos C339(0.72); C178(0.74); C202(0.92); C290(1.02)  LDD2187  [44]
 LDCM0572  Fragment10 Ramos C339(0.65); C178(0.54); C202(0.50); C290(0.19)  LDD2189  [44]
 LDCM0573  Fragment11 Ramos C339(0.03); C178(0.03); C290(0.13); C240(0.30)  LDD2190  [44]
 LDCM0574  Fragment12 Ramos C339(0.55); C178(0.55); C202(0.50); C290(0.21)  LDD2191  [44]
 LDCM0575  Fragment13 Ramos C339(0.99); C178(0.99); C202(0.83); C290(0.48)  LDD2192  [44]
 LDCM0576  Fragment14 Ramos C339(0.90); C178(0.68); C202(0.60); C290(0.73)  LDD2193  [44]
 LDCM0579  Fragment20 Ramos C339(0.43); C178(0.51); C202(0.38); C290(0.27)  LDD2194  [44]
 LDCM0580  Fragment21 Ramos C339(0.88); C178(0.96); C202(0.69); C290(0.40)  LDD2195  [44]
 LDCM0582  Fragment23 Ramos C339(1.14); C178(1.29); C202(0.87); C290(1.20)  LDD2196  [44]
 LDCM0578  Fragment27 Ramos C339(1.01); C178(1.18); C202(0.85); C290(0.45)  LDD2197  [44]
 LDCM0586  Fragment28 Ramos C339(0.61); C178(0.86); C202(0.67); C290(1.23)  LDD2198  [44]
 LDCM0588  Fragment30 Ramos C339(1.24); C178(1.00); C202(1.05); C290(0.26)  LDD2199  [44]
 LDCM0589  Fragment31 Ramos C339(1.22); C178(1.24); C202(0.92); C290(0.32)  LDD2200  [44]
 LDCM0590  Fragment32 Ramos C339(0.51); C178(0.49); C202(0.55); C290(0.29)  LDD2201  [44]
 LDCM0468  Fragment33 HEK-293T C240(0.88); C339(1.04); C73(0.96); C290(1.11)  LDD1671  [42]
 LDCM0596  Fragment38 Ramos C339(1.23); C178(0.76); C202(0.93)  LDD2203  [44]
 LDCM0566  Fragment4 Ramos C339(0.63); C178(0.61); C202(0.61); C290(0.53)  LDD2184  [44]
 LDCM0427  Fragment51 HEK-293T C240(0.83); C339(0.95); C73(0.89); C290(0.98)  LDD1631  [42]
 LDCM0610  Fragment52 Ramos C339(1.47); C178(1.03); C202(1.07); C290(0.76)  LDD2204  [44]
 LDCM0614  Fragment56 Ramos C339(1.49); C178(0.97); C202(1.14); C290(0.34)  LDD2205  [44]
 LDCM0569  Fragment7 Ramos C339(0.55); C178(0.49); C202(0.58); C290(0.51)  LDD2186  [44]
 LDCM0571  Fragment9 Ramos C339(0.48); C178(0.44); C202(0.42); C290(0.16)  LDD2188  [44]
 LDCM0116  HHS-0101 DM93 Y328(0.90); Y204(1.02); Y138(1.22)  LDD0264  [17]
 LDCM0117  HHS-0201 DM93 Y328(0.70); Y138(0.93); Y204(1.08)  LDD0265  [17]
 LDCM0118  HHS-0301 DM93 Y328(0.75); Y204(0.80); Y138(0.85)  LDD0266  [17]
 LDCM0119  HHS-0401 DM93 Y328(0.81); Y138(0.96); Y204(1.05)  LDD0267  [17]
 LDCM0120  HHS-0701 DM93 Y328(0.90); Y204(0.93); Y138(1.93)  LDD0268  [17]
 LDCM0107  IAA HeLa H362(0.00); H246(0.00); H157(0.00); C339(0.00)  LDD0221  [34]
 LDCM0123  JWB131 DM93 Y138(1.17); Y174(2.09); Y204(1.10); Y214(0.68)  LDD0285  [16]
 LDCM0124  JWB142 DM93 Y138(0.39); Y174(0.57); Y204(0.77); Y214(0.84)  LDD0286  [16]
 LDCM0125  JWB146 DM93 Y138(0.97); Y174(0.97); Y204(0.82); Y214(0.46)  LDD0287  [16]
 LDCM0126  JWB150 DM93 Y138(4.14); Y174(4.24); Y204(4.85); Y214(1.53)  LDD0288  [16]
 LDCM0127  JWB152 DM93 Y138(2.38); Y174(4.67); Y204(3.07); Y214(2.29)  LDD0289  [16]
 LDCM0128  JWB198 DM93 Y138(1.22); Y174(1.60); Y204(1.33); Y214(0.15)  LDD0290  [16]
 LDCM0129  JWB202 DM93 Y138(0.58); Y174(0.92); Y204(0.98); Y214(0.53)  LDD0291  [16]
 LDCM0130  JWB211 DM93 Y138(0.68); Y174(0.94); Y204(0.65); Y214(0.23)  LDD0292  [16]
 LDCM0179  JZ128 PC-3 C290(0.00); C339(0.00); C178(0.00)  LDD0462  [14]
 LDCM0022  KB02 HEK-293T C240(1.12); C339(1.06); C73(0.98); C290(0.97)  LDD1492  [42]
 LDCM0023  KB03 HEK-293T C240(1.01); C339(1.05); C73(0.90); C290(0.97)  LDD1497  [42]
 LDCM0024  KB05 G361 C393(2.31)  LDD3311  [13]
 LDCM0109  NEM HeLa H362(0.00); H246(0.00); H157(0.00); H21(0.00)  LDD0223  [34]
 LDCM0627  NUDT7-COV-1 HEK-293T C202(0.72)  LDD2206  [45]
 LDCM0628  OTUB2-COV-1 HEK-293T C290(0.91); C339(0.90); C202(0.77)  LDD2207  [45]
 LDCM0099  Phenelzine HEK-293T 3.00  LDD0386  [1]
 LDCM0131  RA190 MM1.R C339(1.34); C73(1.27)  LDD0304  [46]
 LDCM0019  Staurosporine Hep-G2 2.00  LDD0083  [40]
 LDCM0021  THZ1 HeLa S3 C178(1.14); C339(1.09); C290(1.05); C73(1.02)  LDD0460  [14]
 LDCM0111  W14 Hep-G2 Y3(3.64)  LDD0238  [35]
 LDCM0113  W17 Hep-G2 K147(0.78); R149(0.78); W148(0.78)  LDD0240  [35]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Fructose-bisphosphate aldolase A (ALDOA) Class I fructose-bisphosphate aldolase family P04075
Fructose-bisphosphate aldolase C (ALDOC) Class I fructose-bisphosphate aldolase family P09972
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Huntingtin (HTT) Huntingtin family P42858
Cytokine and receptor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Interferon alpha-4 (IFNA4) Alpha/beta interferon family P05014
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Proliferating cell nuclear antigen (PCNA) PCNA family P12004

The Drug(s) Related To This Target

Approved
Click To Hide/Show 5 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Artenimol . DB11638
Zinc . DB01593
Zinc Acetate . DB14487
Zinc Chloride . DB14533
Zinc Sulfate Unspecified Form . DB14548
Investigative
Click To Hide/Show 4 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
16-di-o-phosphono-d-mannitol . DB04733
16-fructose Diphosphate (Linear Form) . DB02512
Dihydroxyacetone Phosphate . DB04326
N-(4-chlorophenyl)-3-(Phosphonooxy)Naphthalene-2-carboxamide . DB08240

References

1 Hydrazines as versatile chemical biology probes and drug-discovery tools for cofactor-dependent enzymes. bioRxiv, 2020-06.
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Mass spectrometry data entry: PXD037665
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Mass spectrometry data entry: PXD021557 , PXD015828
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Mass spectrometry data entry: PXD028270
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Mass spectrometry data entry: PXD042888
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Mass spectrometry data entry: PXD047840
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Mass spectrometry data entry: PXD044625
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Mass spectrometry data entry: PXD042377
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Mass spectrometry data entry: PXD028853
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Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
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Mass spectrometry data entry: PXD029500 , PXD031647
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Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD029255
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD022279
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Mass spectrometry data entry: PXD039931
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Mass spectrometry data entry: PXD036569
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Mass spectrometry data entry: PXD001377 , PXD005252
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Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD044402
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Mass spectrometry data entry: PXD027578
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