Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0123
Competitor Name
JWB131
Synonyms
SCHEMBL22558406
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 279.32
Lipid-water partition coefficient (xlogp) 1.9
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C12H13N3O3S
IUPAC Name
1-cyclopropylsulfonyl-3-(4-methoxyphenyl)-1,2,4-triazole
Canonical SMILES
COC1=CC=C(C=C1)C2=NN(C=N2)S(=O)(=O)C3CC3
InChI
InChI=1S/C12H13N3O3S/c1-18-10-4-2-9(3-5-10)12-13-8-15(14-12)19(16,17)11-6-7-11/h2-5,8,11H,6-7H2,1H3
InChIKey
GQSKPZWADSFKJL-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
HHS-482
 Probe Info  		50 uM Human melanoma cell lysate (DM93) [1]

Target(s) List of this Competitor

286 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
(3R)-3-hydroxyacyl-CoA dehydrogenase (HSD17B8) LDTP09770 1.09  LDD0285 
1,4-alpha-glucan-branching enzyme (GBE1) LDTP05419 0.70  LDD0285 
14 kDa phosphohistidine phosphatase (PHPT1) LDTP12543 0.59; 0.62  LDD0285 
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) LDTP02356 1.14  LDD0285 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 0.12  LDD0285 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 1.44  LDD0285 
26S proteasome non-ATPase regulatory subunit 3 (PSMD3) LDTP00714 1.29  LDD0285 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 1.13  LDD0285 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 1.03  LDD0285 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 3.50  LDD0285 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 0.91  LDD0285 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 1.00  LDD0285 
5'-3' exoribonuclease 2 (XRN2) LDTP11701 0.89  LDD0285 
6-phosphogluconate dehydrogenase, decarboxylating (PGD) LDTP04499 0.32  LDD0285 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 0.67; 0.83; 1.08 ...  LDD0285 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 0.99  LDD0285 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 1.02  LDD0285 
Acetyl-CoA carboxylase 1 (ACACA) LDTP05742 0.55  LDD0285 
Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) LDTP12463 0.93  LDD0285 
Actin, alpha cardiac muscle 1 (ACTC1) LDTP05069 0.85  LDD0285 
Actin, cytoplasmic 1 (ACTB) LDTP04876 1.01; 0.85; 1.45 ...  LDD0285 
Adenosylhomocysteinase (AHCY) LDTP03242 0.94; 1.08  LDD0285 
Adenylosuccinate synthetase isozyme 2 (ADSS2) LDTP03541 1.21  LDD0285 
ADP-ribose pyrophosphatase, mitochondrial (NUDT9) LDTP11318 0.80  LDD0285 
ADP-ribosylation factor 1 (ARF1) LDTP05192 0.86; 1.10  LDD0285 
ADP-ribosylation factor 3 (ARF3) LDTP04907 0.86; 1.10  LDD0285 
ADP-ribosylation factor 4 (ARF4) LDTP02942 0.86; 1.10  LDD0285 
ADP-ribosylation factor 5 (ARF5) LDTP05193 0.86; 1.10  LDD0285 
ADP-sugar pyrophosphatase (NUDT5) LDTP13462 1.54  LDD0285 
Aflatoxin B1 aldehyde reductase member 2 (AKR7A2) LDTP00776 0.88; 0.96; 0.77 ...  LDD0285 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 0.88; 0.68  LDD0285 
Alcohol dehydrogenase class-3 (ADH5) LDTP02587 0.78; 1.35  LDD0285 
Aldo-keto reductase family 1 member A1 (AKR1A1) LDTP02729 2.96  LDD0285 
Alpha-aminoadipic semialdehyde synthase, mitochondrial (AASS) LDTP13186 0.94; 0.06; 1.30  LDD0285 
Alpha-enolase (ENO1) LDTP02159 0.94; 0.83; 1.91 ...  LDD0285 
Amidophosphoribosyltransferase (PPAT) LDTP05480 0.94  LDD0285 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 0.05; 0.89  LDD0285 
Asparagine synthetase [glutamine-hydrolyzing] (ASNS) LDTP02264 0.86  LDD0285 
Asparagine--tRNA ligase, cytoplasmic (NARS1) LDTP00866 1.04; 1.00; 1.31 ...  LDD0285 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 5.87; 0.87; 0.99  LDD0285 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 0.83; 0.82; 1.06  LDD0285 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 0.76; 2.60  LDD0285 
ATP-citrate synthase (ACLY) LDTP04561 1.04; 1.41; 1.24 ...  LDD0285 
ATP-dependent 6-phosphofructokinase, liver type (PFKL) LDTP02925 0.84  LDD0285 
ATP-dependent 6-phosphofructokinase, muscle type (PFKM) LDTP02261 0.57  LDD0285 
ATP-dependent RNA helicase A (DHX9) LDTP05550 0.81; 0.70  LDD0285 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 1.04  LDD0285 
ATPase MORC2 (MORC2) LDTP14308 1.13  LDD0285 
Aurora kinase B (AURKB) LDTP10346 2.98  LDD0285 
Bifunctional coenzyme A synthase (COASY) LDTP05736 0.72  LDD0285 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 0.89; 1.02  LDD0285 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 2.13  LDD0285 
Biliverdin reductase A (BLVRA) LDTP04552 0.68  LDD0285 
Biotinidase (BTD) LDTP04030 1.21  LDD0285 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 0.70; 0.74; 0.84 ...  LDD0285 
Calcyclin-binding protein (CACYBP) LDTP12163 1.39; 1.42; 1.24  LDD0285 
Carbonyl reductase [NADPH] 1 (CBR1) LDTP02831 1.39  LDD0285 
Carbonyl reductase [NADPH] 3 (CBR3) LDTP01321 1.05  LDD0285 
Catalase (CAT) LDTP02001 1.09  LDD0285 
Cathepsin B (CTSB) LDTP02223 0.82; 0.85; 0.85 ...  LDD0285 
Cathepsin D (CTSD) LDTP02198 1.40; 0.87  LDD0285 
Cathepsin Z (CTSZ) LDTP13147 0.82; 1.22; 1.41 ...  LDD0285 
Citrate synthase, mitochondrial (CS) LDTP01205 0.50; 1.05; 0.79  LDD0285 
Cleavage and polyadenylation specificity factor subunit 5 (NUDT21) LDTP00873 1.00  LDD0285 
CTP synthase 1 (CTPS1) LDTP02922 0.61; 0.88; 1.04  LDD0285 
Cyclin-dependent kinase 1 (CDK1) LDTP02149 0.67; 1.01; 0.81 ...  LDD0285 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 0.67; 0.81  LDD0285 
Cystathionine gamma-lyase (CTH) LDTP03656 1.06  LDD0285 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 1.20  LDD0285 
Cytochrome c oxidase assembly factor 7 (COA7) LDTP10137 0.80  LDD0285 
Cytoglobin (CYGB) LDTP09656 1.13; 1.66  LDD0285 
Cytosol aminopeptidase (LAP3) LDTP03455 0.69  LDD0285 
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 0.98; 0.84  LDD0285 
Dehydrogenase/reductase SDR family member 11 (DHRS11) LDTP07678 0.91  LDD0285 
Dihydropteridine reductase (QDPR) LDTP02342 0.52  LDD0285 
Dipeptidyl peptidase 3 (DPP3) LDTP12803 1.02  LDD0285 
DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 0.96  LDD0285 
DNA replication licensing factor MCM2 (MCM2) LDTP04286 0.81  LDD0285 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 3.34  LDD0285 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 1.90  LDD0285 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 0.05  LDD0285 
DNA replication licensing factor MCM7 (MCM7) LDTP03682 0.87  LDD0285 
Dual specificity protein phosphatase 23 (DUSP23) LDTP11289 0.84  LDD0285 
Dual specificity protein phosphatase 3 (DUSP3) LDTP04415 0.52  LDD0285 
E3 ubiquitin-protein ligase ARIH2 (ARIH2) LDTP01575 0.73  LDD0285 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 1.01  LDD0285 
E3 ubiquitin-protein ligase UBR4 (UBR4) LDTP07118 0.52  LDD0285 
EH domain-containing protein 4 (EHD4) LDTP11788 0.82  LDD0285 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 1.20; 0.78; 0.91 ...  LDD0285 
Elongation factor 2 (EEF2) LDTP02672 2.42; 2.15; 0.94 ...  LDD0285 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 1.09; 0.75; 0.59 ...  LDD0285 
Endoplasmic reticulum chaperone BiP (HSPA5) LDTP02534 8.51; 0.97; 1.46 ...  LDD0285 
Enoyl-CoA hydratase, mitochondrial (ECHS1) LDTP03518 0.86  LDD0285 
ERO1-like protein alpha (ERO1A) LDTP10386 2.09; 1.63  LDD0285 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 0.95; 0.98; 0.91 ...  LDD0285 
Eukaryotic initiation factor 4A-III (EIF4A3) LDTP03861 0.90  LDD0285 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 0.86  LDD0285 
Exosome complex exonuclease RRP44 (DIS3) LDTP13887 0.77  LDD0285 
Farnesyl pyrophosphate synthase (FDPS) LDTP02721 0.93  LDD0285 
Fatty acid CoA ligase Acsl3 (ACSL3) LDTP01634 0.68  LDD0285 
Fatty acid synthase (FASN) LDTP04243 1.41; 1.44; 1.05 ...  LDD0285 
Flap endonuclease 1 (FEN1) LDTP03872 0.73  LDD0285 
Fructose-2,6-bisphosphatase TIGAR (TIGAR) LDTP12405 0.94  LDD0285 
Fructose-bisphosphate aldolase A (ALDOA) LDTP02008 1.17; 2.09; 1.10 ...  LDD0285 
Fumarate hydratase, mitochondrial (FH) LDTP02235 1.08  LDD0285 
Fumarylacetoacetase (FAH) LDTP02868 1.61  LDD0285 
Galactokinase (GALK1) LDTP04424 0.99  LDD0285 
Gamma-enolase (ENO2) LDTP02328 1.12; 1.29  LDD0285 
GDP-mannose 4,6 dehydratase (GMDS) LDTP00999 0.95  LDD0285 
Geranylgeranyl transferase type-2 subunit beta (RABGGTB) LDTP04569 0.99  LDD0285 
Glucosamine-6-phosphate isomerase 1 (GNPDA1) LDTP04113 1.07  LDD0285 
Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 0.96; 1.15  LDD0285 
Glucose-6-phosphate isomerase (GPI) LDTP02162 0.34; 1.35; 0.95  LDD0285 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) LDTP05481 0.96; 1.18  LDD0285 
Glutaredoxin-1 (GLRX) LDTP03786 1.05  LDD0285 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 1.30; 0.62  LDD0285 
Glutathione S-transferase A4 (GSTA4) LDTP00575 2.09  LDD0285 
Glutathione S-transferase kappa 1 (GSTK1) LDTP13900 0.89  LDD0285 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 0.97  LDD0285 
Glutathione S-transferase P (GSTP1) LDTP02333 0.72; 1.08; 0.82 ...  LDD0285 
Glutathione synthetase (GSS) LDTP04200 1.00  LDD0285 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 0.70; 1.03; 1.12 ...  LDD0285 
Glycine--tRNA ligase (GARS1) LDTP03946 0.58; 2.07; 1.05  LDD0285 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 0.85; 0.88; 0.97 ...  LDD0285 
Glycogen phosphorylase, liver form (PYGL) LDTP02161 0.72  LDD0285 
GTP-binding nuclear protein Ran (RAN) LDTP05007 0.80; 0.86; 1.08 ...  LDD0285 
HBS1-like protein (HBS1L) LDTP14019 0.78  LDD0285 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 1.00; 0.66; 1.15 ...  LDD0285 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 0.52; 0.89; 0.83 ...  LDD0285 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 0.60  LDD0285 
Histone deacetylase 1 (HDAC1) LDTP05918 0.82  LDD0285 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 0.79  LDD0285 
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL) LDTP03794 1.40  LDD0285 
Inorganic pyrophosphatase (PPA1) LDTP14854 1.19; 0.95; 0.77 ...  LDD0285 
Inorganic pyrophosphatase 2, mitochondrial (PPA2) LDTP11842 0.93  LDD0285 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 0.58; 1.15; 0.90 ...  LDD0285 
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) LDTP11700 1.51  LDD0285 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 0.90; 0.96; 1.03  LDD0285 
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (IDH3B) LDTP00885 0.28  LDD0285 
Isoleucine--tRNA ligase, cytoplasmic (IARS1) LDTP03947 1.53  LDD0285 
Kynurenine--oxoglutarate transaminase 3 (KYAT3) LDTP07763 0.27  LDD0285 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 0.84; 0.96; 1.12 ...  LDD0285 
L-lactate dehydrogenase B chain (LDHB) LDTP02179 0.91; 1.01; 1.01 ...  LDD0285 
L-xylulose reductase (DCXR) LDTP08082 1.07  LDD0285 
Lactoylglutathione lyase (GLO1) LDTP05434 1.10  LDD0285 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 0.80  LDD0285 
Lymphokine-activated killer T-cell-originated protein kinase (PBK) LDTP10500 0.68; 1.34; 0.99  LDD0285 
Lysosomal protective protein (CTSA) LDTP02505 1.18  LDD0285 
Macrophage migration inhibitory factor (MIF) LDTP02713 0.93; 1.31; 1.22 ...  LDD0285 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 0.83; 1.09  LDD0285 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 0.62; 0.58; 0.98 ...  LDD0285 
Mannose-1-phosphate guanyltransferase beta (GMPPB) LDTP14141 1.05  LDD0285 
MAP kinase-activated protein kinase 3 (MAPKAPK3) LDTP06589 0.28; 0.87  LDD0285 
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) LDTP02565 0.77; 1.02; 0.28 ...  LDD0285 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 0.82  LDD0285 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 2.35  LDD0285 
Methylthioribulose-1-phosphate dehydratase (APIP) LDTP10368 1.37  LDD0285 
Mitochondrial-processing peptidase subunit beta (PMPCB) LDTP01220 0.15  LDD0285 
Mitogen-activated protein kinase 1 (MAPK1) LDTP03445 1.23; 0.89  LDD0285 
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) LDTP01005 1.47  LDD0285 
Myosin-10 (MYH10) LDTP03765 0.74; 1.31; 0.96 ...  LDD0285 
Myosin-9 (MYH9) LDTP03764 1.13; 1.35; 0.85 ...  LDD0285 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 1.17  LDD0285 
NAD(P)H dehydrogenase [quinone] 1 (NQO1) LDTP02798 1.28; 0.90; 0.96  LDD0285 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 0.80  LDD0285 
NEDD8-activating enzyme E1 regulatory subunit (NAE1) LDTP05925 0.78  LDD0285 
NEDD8-conjugating enzyme Ubc12 (UBE2M) LDTP04898 1.41  LDD0285 
Neutral alpha-glucosidase AB (GANAB) LDTP06192 2.04  LDD0285 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 1.75  LDD0285 
Nucleoside diphosphate kinase B (NME2) LDTP03169 1.51  LDD0285 
Omega-amidase NIT2 (NIT2) LDTP12428 0.80; 1.04; 0.77 ...  LDD0285 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 1.13; 1.09; 1.17  LDD0285 
Palmitoyltransferase ZDHHC17 (ZDHHC17) LDTP08456 1.34  LDD0285 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 1.18; 1.07  LDD0285 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 1.07  LDD0285 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 1.44; 0.96  LDD0285 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 0.36; 1.56; 0.80  LDD0285 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) LDTP05912 1.02  LDD0285 
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3) LDTP11823 1.03  LDD0285 
Peroxiredoxin-1 (PRDX1) LDTP05503 2.32; 1.17; 0.96  LDD0285 
Peroxiredoxin-4 (PRDX4) LDTP05773 1.12; 0.90  LDD0285 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 0.67  LDD0285 
Phosphatidylinositide phosphatase SAC2 (INPP5F) LDTP13867 0.88  LDD0285 
Phosphoglucomutase-1 (PGM1) LDTP03818 2.99  LDD0285 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 1.15; 0.99; 1.08 ...  LDD0285 
Phosphoglycerate mutase 1 (PGAM1) LDTP02963 0.77; 1.68; 1.25 ...  LDD0285 
Phosphoserine aminotransferase (PSAT1) LDTP14198 1.29; 0.81; 0.75 ...  LDD0285 
Poly(A) polymerase alpha (PAPOLA) LDTP04394 0.77  LDD0285 
Probable 18S rRNA (guanine-N(7))-methyltransferase (BUD23) LDTP00845 1.18  LDD0285 
Probable aminopeptidase NPEPL1 (NPEPL1) LDTP09126 0.80  LDD0285 
Probable E3 ubiquitin-protein ligase IRF2BPL (IRF2BPL) LDTP11759 0.69  LDD0285 
Prolyl endopeptidase (PREP) LDTP04163 0.30  LDD0285 
Prostaglandin reductase 1 (PTGR1) LDTP06227 1.05; 1.25; 1.02  LDD0285 
Prostaglandin reductase 2 (PTGR2) LDTP08979 1.35; 2.92; 1.99  LDD0285 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 0.89; 0.91  LDD0285 
Proteasome subunit alpha type-2 (PSMA2) LDTP03331 1.00; 0.90; 0.89  LDD0285 
Proteasome subunit alpha type-3 (PSMA3) LDTP03332 0.96  LDD0285 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 1.00; 1.36; 0.58 ...  LDD0285 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 0.74; 0.91; 0.50 ...  LDD0285 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 1.09; 1.06  LDD0285 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 0.55; 0.16  LDD0285 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 0.52; 0.79  LDD0285 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 1.04; 0.58  LDD0285 
Protein arginine N-methyltransferase 5 (PRMT5) LDTP00418 0.67  LDD0285 
Protein disulfide-isomerase (P4HB) LDTP02188 3.08; 1.10; 1.03 ...  LDD0285 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 0.90; 0.98; 1.17 ...  LDD0285 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 1.20; 0.87; 2.55  LDD0285 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 1.32  LDD0285 
Protein kinase C delta type (PRKCD) LDTP05461 1.37  LDD0285 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 1.04  LDD0285 
Putative elongation factor 1-alpha-like 3 (EEF1A1P5) LDTP15029 1.20; 0.78; 0.91 ...  LDD0285 
Pyridoxine-5'-phosphate oxidase (PNPO) LDTP12691 0.90  LDD0285 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 0.59; 0.71  LDD0285 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 0.87; 1.03; 1.18 ...  LDD0285 
Pyruvate kinase PKM (PKM) LDTP02733 0.38; 1.07; 0.48 ...  LDD0285 
Queuine tRNA-ribosyltransferase catalytic subunit 1 (QTRT1) LDTP11400 1.90  LDD0285 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 0.90; 0.90  LDD0285 
RAC-gamma serine/threonine-protein kinase (AKT3) LDTP13799 0.96; 0.90  LDD0285 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 0.83; 1.14  LDD0285 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 0.50  LDD0285 
Ribonucleoside-diphosphate reductase large subunit (RRM1) LDTP03259 0.89  LDD0285 
RING finger and CHY zinc finger domain-containing protein 1 (RCHY1) LDTP10686 0.99  LDD0285 
RNA demethylase ALKBH5 (ALKBH5) LDTP07547 1.10  LDD0285 
RuvB-like 1 (RUVBL1) LDTP13816 1.03  LDD0285 
S-adenosylmethionine synthase isoform type-2 (MAT2A) LDTP03577 1.36; 0.78  LDD0285 
S-formylglutathione hydrolase (ESD) LDTP02521 0.85; 1.04  LDD0285 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 0.32  LDD0285 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 1.02  LDD0285 
Sepiapterin reductase (SPR) LDTP03730 0.88; 1.17  LDD0285 
Septin-2 (SEPTIN2) LDTP06279 1.34  LDD0285 
Septin-7 (SEPTIN7) LDTP06513 0.46; 0.63  LDD0285 
Septin-9 (SEPTIN9) LDTP13272 0.80; 1.59; 0.89  LDD0285 
Serine hydroxymethyltransferase, cytosolic (SHMT1) LDTP03688 1.03  LDD0285 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 0.42  LDD0285 
Serine/threonine-protein kinase PAK 2 (PAK2) LDTP05776 1.16  LDD0285 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 0.67  LDD0285 
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) LDTP05064 1.19  LDD0285 
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB) LDTP04998 1.19  LDD0285 
Serine/threonine-protein phosphatase 4 catalytic subunit (PPP4C) LDTP04870 1.19  LDD0285 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 0.89  LDD0285 
Serine/threonine-protein phosphatase 6 catalytic subunit (PPP6C) LDTP00333 0.78  LDD0285 
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) LDTP04959 0.66; 0.99  LDD0285 
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) LDTP04960 0.66; 0.92  LDD0285 
Sialic acid synthase (NANS) LDTP12473 1.35; 0.97; 1.06  LDD0285 
Spermidine synthase (SRM) LDTP03008 0.95  LDD0285 
Spliceosome RNA helicase DDX39B (DDX39B) LDTP05991 0.61  LDD0285 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 0.84; 0.88  LDD0285 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 1.00  LDD0285 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 2.37  LDD0285 
SUMO-activating enzyme subunit 2 (UBA2) LDTP13156 1.30  LDD0285 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 2.34; 1.08  LDD0285 
Thimet oligopeptidase (THOP1) LDTP04542 1.16  LDD0285 
Thioredoxin domain-containing protein 12 (TXNDC12) LDTP01707 1.02  LDD0285 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 0.81; 0.95; 0.71 ...  LDD0285 
Threonine--tRNA ligase 1, cytoplasmic (TARS1) LDTP03365 0.80; 0.91; 0.73 ...  LDD0285 
Thymidylate kinase (DTYMK) LDTP03258 1.04; 0.71  LDD0285 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 0.92; 1.04; 0.64 ...  LDD0285 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 0.94  LDD0285 
Transketolase (TKT) LDTP03487 0.88; 1.01; 0.82 ...  LDD0285 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 1.00  LDD0285 
Triosephosphate isomerase (TPI1) LDTP04851 1.15; 3.20; 0.67  LDD0285 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 0.99  LDD0285 
Tryptophan--tRNA ligase, cytoplasmic (WARS1) LDTP03222 1.02; 0.19; 0.51  LDD0285 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 0.88; 0.87; 0.88 ...  LDD0285 
Tubulin alpha-1B chain (TUBA1B) LDTP05074 0.88; 0.87; 0.88 ...  LDD0285 
Tubulin alpha-1C chain (TUBA1C) LDTP11074 0.97  LDD0285 
Tyrosine--tRNA ligase, cytoplasmic (YARS1) LDTP04617 0.92; 0.89  LDD0285 
Tyrosine-protein kinase CSK (CSK) LDTP03944 0.99  LDD0285 
Ubiquitin carboxyl-terminal hydrolase 14 (USP14) LDTP04618 1.05  LDD0285 
Ubiquitin carboxyl-terminal hydrolase 39 (USP39) LDTP06903 1.29  LDD0285 
Ubiquitin carboxyl-terminal hydrolase 4 (USP4) LDTP05749 1.09  LDD0285 
Ubiquitin-conjugating enzyme E2 N (UBE2N) LDTP04900 1.46; 1.88; 1.49  LDD0285 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 0.98; 1.78; 0.96 ...  LDD0285 
UDP-glucose 4-epimerase (GALE) LDTP06111 1.21  LDD0285 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 0.98; 0.34; 0.98 ...  LDD0285 
UMP-CMP kinase (CMPK1) LDTP03519 0.91  LDD0285 
Unconventional myosin-Ie (MYO1E) LDTP05708 2.81  LDD0285 
Uridine 5'-monophosphate synthase (UMPS) LDTP02548 0.75  LDD0285 
Uridine phosphorylase 1 (UPP1) LDTP06643 1.13; 0.37; 1.05 ...  LDD0285 
Uroporphyrinogen decarboxylase (UROD) LDTP02135 1.26; 0.78  LDD0285 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 0.93; 0.95; 1.05  LDD0285 
V-type proton ATPase subunit E 2 (ATP6V1E2) LDTP15684 0.77  LDD0285 
Valine--tRNA ligase (VARS1) LDTP03366 1.24  LDD0285 
WD repeat-containing protein 82 (WDR82) LDTP07715 0.62  LDD0285 
Xaa-Pro aminopeptidase 1 (XPNPEP1) LDTP12444 1.13; 0.86  LDD0285 
Xaa-Pro dipeptidase (PEPD) LDTP02639 1.70  LDD0285 
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⏷ Show the Full List of 286 Enzyme
39 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein epsilon (YWHAE) LDTP04969 1.31; 1.07; 0.92 ...  LDD0285 
14-3-3 protein gamma (YWHAG) LDTP04953 1.17  LDD0285 
14-3-3 protein theta (YWHAQ) LDTP03385 0.93; 1.26  LDD0285 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 0.91; 1.07; 1.44 ...  LDD0285 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 0.85; 1.05  LDD0285 
Alpha-synuclein (SNCA) LDTP03848 1.60  LDD0285 
Annexin A2 (ANXA2) LDTP02199 0.98; 1.13; 0.64 ...  LDD0285 
Annexin A5 (ANXA5) LDTP02307 0.90; 1.42; 1.13 ...  LDD0285 
Annexin A6 (ANXA6) LDTP02247 2.39; 0.96  LDD0285 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 1.48  LDD0285 
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 0.62; 0.85  LDD0285 
Calreticulin (CALR) LDTP03402 0.97; 1.10; 1.01 ...  LDD0285 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 1.18; 0.81; 1.01 ...  LDD0285 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 1.02; 0.95; 0.92 ...  LDD0285 
Clathrin heavy chain 1 (CLTC) LDTP05252 0.57; 0.74  LDD0285 
Copine-3 (CPNE3) LDTP01133 1.10; 0.98  LDD0285 
Cystatin-B (CSTB) LDTP02009 1.22; 1.63; 0.92  LDD0285 
Dihydropyrimidinase-related protein 2 (DPYSL2) LDTP06554 1.76; 0.61; 0.73  LDD0285 
Eukaryotic translation initiation factor 5A-1 (EIF5A) LDTP05056 0.97  LDD0285 
Exportin-1 (XPO1) LDTP00501 0.80  LDD0285 
Filamin-A (FLNA) LDTP03107 1.03; 0.96  LDD0285 
Galectin-3 (LGALS3) LDTP02929 0.88  LDD0285 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 0.81; 0.76; 1.59 ...  LDD0285 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 0.75  LDD0285 
Importin subunit beta-1 (KPNB1) LDTP06242 0.78  LDD0285 
mRNA export factor RAE1 (RAE1) LDTP05122 1.51  LDD0285 
Protein SEC13 homolog (SEC13) LDTP04707 0.72  LDD0285 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 1.27  LDD0285 
T-complex protein 1 subunit delta (CCT4) LDTP04391 0.67; 0.99; 1.06 ...  LDD0285 
Talin-1 (TLN1) LDTP14031 0.80; 0.26; 0.49 ...  LDD0285 
Thioredoxin domain-containing protein 17 (TXNDC17) LDTP11103 1.98; 1.43; 1.21  LDD0285 
Transferrin receptor protein 1 (TFRC) LDTP01969 1.54  LDD0285 
Ubiquilin-4 (UBQLN4) LDTP12533 0.84  LDD0285 
V-type proton ATPase subunit B, brain isoform (ATP6V1B2) LDTP03104 1.22  LDD0285 
V-type proton ATPase subunit C 1 (ATP6V1C1) LDTP03105 0.88  LDD0285 
V-type proton ATPase subunit E 1 (ATP6V1E1) LDTP03811 0.77  LDD0285 
V-type proton ATPase subunit G 1 (ATP6V1G1) LDTP01185 0.89  LDD0285 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 1.07  LDD0285 
Voltage-gated potassium channel subunit beta-2 (KCNAB2) LDTP05817 1.02  LDD0285 
------------------------------------------------------------------------------------
⏷ Show the Full List of 39 Transporter and channel
7 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
High mobility group protein B1 (HMGB1) LDTP02343 0.78; 0.74; 1.00 ...  LDD0285 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 0.63  LDD0285 
Signal transducer and activator of transcription 3 (STAT3) LDTP03903 5.48  LDD0285 
Signal transducer and activator of transcription 5A (STAT5A) LDTP03971 1.17  LDD0285 
Transcription factor SOX-10 (SOX10) LDTP04752 0.86  LDD0285 
Transcription factor SOX-9 (SOX9) LDTP04179 0.89  LDD0285 
Y-box-binding protein 1 (YBX1) LDTP05065 1.12; 0.88; 1.06  LDD0285 
------------------------------------------------------------------------------------
⏷ Show the Full List of 7 Transcription factor
273 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
10 kDa heat shock protein, mitochondrial (HSPE1) LDTP04931 2.92  LDD0285 
14-3-3 protein beta/alpha (YWHAB) LDTP03617 1.10; 1.10  LDD0285 
14-3-3 protein eta (YWHAH) LDTP05442 0.49  LDD0285 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 0.90  LDD0285 
55 kDa erythrocyte membrane protein (MPP1) LDTP05233 1.20  LDD0285 
Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) LDTP03871 2.52  LDD0285 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 0.74  LDD0285 
Actin nucleation-promoting factor WASL (WASL) LDTP00263 1.55  LDD0285 
Actin-related protein 3 (ACTR3) LDTP04902 0.96; 0.72; 0.34 ...  LDD0285 
Adapter molecule crk (CRK) LDTP04091 0.79; 0.81; 0.81  LDD0285 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 0.99; 0.74; 1.13  LDD0285 
AH receptor-interacting protein (AIP) LDTP00202 0.87  LDD0285 
Alpha-actinin-1 (ACTN1) LDTP02631 0.37; 0.74; 1.22  LDD0285 
Alpha-centractin (ACTR1A) LDTP04904 0.62  LDD0285 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 0.94  LDD0285 
Anamorsin (CIAPIN1) LDTP07385 1.23  LDD0285 
Ankyrin repeat and MYND domain-containing protein 2 (ANKMY2) LDTP17620 1.02  LDD0285 
Ankyrin repeat domain-containing protein 39 (ANKRD39) LDTP19320 1.00  LDD0285 
Annexin A3 (ANXA3) LDTP02620 0.91  LDD0285 
Annexin A7 (ANXA7) LDTP03030 0.83  LDD0285 
Apoptosis inhibitor 5 (API5) LDTP11575 0.77  LDD0285 
Beta-parvin (PARVB) LDTP12184 1.27  LDD0285 
Bifunctional purine biosynthesis protein ATIC (ATIC) LDTP03612 0.80; 0.72; 0.93 ...  LDD0285 
Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (ARFGEF2) LDTP14237 0.92  LDD0285 
C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9) LDTP00934 1.28; 0.83  LDD0285 
Calpain small subunit 1 (CAPNS1) LDTP02047 0.88  LDD0285 
Calponin-3 (CNN3) LDTP06383 0.93; 0.90; 0.91 ...  LDD0285 
Calumenin (CALU) LDTP00887 0.88; 0.85; 0.97 ...  LDD0285 
cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) LDTP02697 0.69  LDD0285 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 1.02; 1.03; 1.44 ...  LDD0285 
Cell cycle and apoptosis regulator protein 2 (CCAR2) LDTP08760 0.37  LDD0285 
Coatomer subunit alpha (COPA) LDTP04571 0.84  LDD0285 
Coatomer subunit beta (COPB1) LDTP04570 1.02  LDD0285 
Coatomer subunit gamma-1 (COPG1) LDTP14216 1.05  LDD0285 
Cofilin-1 (CFL1) LDTP03244 0.97; 1.06; 1.13 ...  LDD0285 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 1.12  LDD0285 
Condensin complex subunit 2 (NCAPH) LDTP06268 0.97  LDD0285 
Copper transport protein ATOX1 (ATOX1) LDTP00229 0.96  LDD0285 
Coronin-1B (CORO1B) LDTP11101 1.26  LDD0285 
Coronin-1C (CORO1C) LDTP13580 0.83  LDD0285 
Crk-like protein (CRKL) LDTP04092 1.04; 0.28; 0.74  LDD0285 
Cysteine and glycine-rich protein 1 (CSRP1) LDTP03106 0.88; 0.82; 1.12  LDD0285 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 1.01; 0.73; 0.92 ...  LDD0285 
Cytoplasmic FMR1-interacting protein 1 (CYFIP1) LDTP07958 0.71  LDD0285 
Cytotoxic granule associated RNA binding protein TIA1 (TIA1) LDTP03598 1.18  LDD0285 
Destrin (DSTN) LDTP04887 0.75  LDD0285 
DnaJ homolog subfamily A member 2 (DNAJA2) LDTP01073 1.38  LDD0285 
DnaJ homolog subfamily B member 1 (DNAJB1) LDTP03325 1.09  LDD0285 
DnaJ homolog subfamily C member 3 (DNAJC3) LDTP05789 1.11  LDD0285 
DnaJ homolog subfamily C member 8 (DNAJC8) LDTP01361 0.95  LDD0285 
Drebrin-like protein (DBNL) LDTP13399 0.98; 0.73; 0.48  LDD0285 
Dynactin subunit 1 (DCTN1) LDTP06082 0.69  LDD0285 
Dynactin subunit 2 (DCTN2) LDTP05922 1.06  LDD0285 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 0.89  LDD0285 
Dynein light chain 2, cytoplasmic (DYNLL2) LDTP10308 0.91  LDD0285 
Elongation factor 1-beta (EEF1B2) LDTP03283 0.87; 0.88; 0.86 ...  LDD0285 
Elongation factor 1-delta (EEF1D) LDTP03499 0.95; 1.01; 0.44 ...  LDD0285 
Elongation factor 1-gamma (EEF1G) LDTP03367 0.86; 1.02; 0.96  LDD0285 
Endoplasmic reticulum resident protein 29 (ERP29) LDTP03509 1.32; 0.97  LDD0285 
Endoplasmin (HSP90B1) LDTP02734 0.87; 1.09; 1.04 ...  LDD0285 
Enhancer of mRNA-decapping protein 3 (EDC3) LDTP10299 1.29  LDD0285 
Epidermal growth factor receptor substrate 15-like 1 (EPS15L1) LDTP13097 1.26  LDD0285 
Eukaryotic translation initiation factor 1 (EIF1) LDTP03953 0.99  LDD0285 
Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX) LDTP04129 0.77  LDD0285 
Eukaryotic translation initiation factor 1b (EIF1B) LDTP16815 0.99  LDD0285 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 0.76  LDD0285 
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) LDTP03027 0.74  LDD0285 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 0.82  LDD0285 
Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 0.90  LDD0285 
Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 1.24  LDD0285 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 1.29  LDD0285 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 0.86; 1.30  LDD0285 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 1.26  LDD0285 
F-actin-uncapping protein LRRC16A (CARMIL1) LDTP07261 0.92  LDD0285 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 1.04; 1.03  LDD0285 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 0.86; 1.06; 0.91 ...  LDD0285 
Gelsolin (GSN) LDTP02145 0.92; 0.94; 1.07 ...  LDD0285 
General transcription factor IIF subunit 2 (GTF2F2) LDTP02703 0.73; 0.74  LDD0285 
Growth factor receptor-bound protein 2 (GRB2) LDTP05035 1.02  LDD0285 
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPVD1) LDTP06255 1.05  LDD0285 
Heat shock 70 kDa protein 1A (HSPA1A) LDTP02434 0.97; 1.18; 1.37 ...  LDD0285 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 1.18; 1.12; 0.84 ...  LDD0285 
Heat shock 70 kDa protein 4L (HSPA4L) LDTP14545 1.03  LDD0285 
Heat shock protein 105 kDa (HSPH1) LDTP09811 1.16; 1.13  LDD0285 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 0.82  LDD0285 
Heat shock protein beta-1 (HSPB1) LDTP02053 0.98; 0.79; 0.88 ...  LDD0285 
Heme-binding protein 1 (HEBP1) LDTP16078 0.83; 0.68  LDD0285 
Hepatoma-derived growth factor (HDGF) LDTP04483 0.73  LDD0285 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 0.82; 0.82  LDD0285 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 0.97; 0.91; 0.97 ...  LDD0285 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 0.69; 0.90; 1.30  LDD0285 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 0.98  LDD0285 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 1.12; 0.88; 1.00 ...  LDD0285 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 0.96; 1.00; 0.65 ...  LDD0285 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 0.81; 1.08; 0.91 ...  LDD0285 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 0.85  LDD0285 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 1.34  LDD0285 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 0.87; 0.89; 1.45 ...  LDD0285 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 0.52; 0.99; 0.99 ...  LDD0285 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 1.01; 0.87; 0.80 ...  LDD0285 
Histone H2B type 1-D (H2BC5) LDTP04822 0.82; 1.32; 1.51  LDD0285 
Histone H2B type 1-L (H2BC13) LDTP11001 1.47  LDD0285 
Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) LDTP05004 2.36; 1.14  LDD0285 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 0.94; 0.98  LDD0285 
Hsc70-interacting protein (ST13) LDTP04367 0.84; 0.87  LDD0285 
Influenza virus NS1A-binding protein (IVNS1ABP) LDTP14309 0.99  LDD0285 
Integrator complex subunit 10 (INTS10) LDTP16111 0.99  LDD0285 
IST1 homolog (IST1) LDTP04593 0.87  LDD0285 
Kelch-like protein 36 (KLHL36) LDTP08871 1.20  LDD0285 
Kinesin light chain 1 (KLC1) LDTP05533 1.44; 0.65  LDD0285 
Kinesin light chain 2 (KLC2) LDTP11695 1.44; 0.65  LDD0285 
Laminin subunit beta-2 (LAMB2) LDTP04691 0.99  LDD0285 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 1.05  LDD0285 
Large ribosomal subunit protein eL21 (RPL21) LDTP04107 1.24; 0.87; 0.85  LDD0285 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 0.88; 0.88  LDD0285 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 0.34; 0.92  LDD0285 
Large ribosomal subunit protein eL29 (RPL29) LDTP04140 1.04  LDD0285 
Large ribosomal subunit protein eL31 (RPL31) LDTP05023 1.79; 0.81  LDD0285 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 0.66  LDD0285 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 0.81  LDD0285 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 0.87  LDD0285 
Large ribosomal subunit protein eL37 (RPL37) LDTP04943 0.94  LDD0285 
Large ribosomal subunit protein eL43 (RPL37A) LDTP04926 1.00  LDD0285 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 20.00  LDD0285 
Large ribosomal subunit protein uL13 (RPL13A) LDTP03899 0.66; 0.61  LDD0285 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 0.94  LDD0285 
Large ribosomal subunit protein uL15 (RPL27A) LDTP04105 1.14  LDD0285 
Large ribosomal subunit protein uL16 (RPL10) LDTP03395 0.62  LDD0285 
Large ribosomal subunit protein uL18 (RPL5) LDTP04106 0.69  LDD0285 
Large ribosomal subunit protein uL2 (RPL8) LDTP05027 0.95  LDD0285 
Large ribosomal subunit protein uL22 (RPL17) LDTP02961 0.81  LDD0285 
Large ribosomal subunit protein uL29 (RPL35) LDTP03999 0.91  LDD0285 
Large ribosomal subunit protein uL30 (RPL7) LDTP02944 0.77  LDD0285 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 0.78; 0.81; 0.61  LDD0285 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 1.05; 1.00  LDD0285 
LIM domain and actin-binding protein 1 (LIMA1) LDTP13260 0.75; 0.73  LDD0285 
LRP chaperone MESD (MESD) LDTP06191 0.74  LDD0285 
Macrophage-capping protein (CAPG) LDTP03877 0.82; 0.96  LDD0285 
Microtubule-associated protein 4 (MAP4) LDTP03404 0.96  LDD0285 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 0.51  LDD0285 
Muscleblind-like protein 1 (MBNL1) LDTP12478 1.31; 1.17  LDD0285 
Muscleblind-like protein 2 (MBNL2) LDTP07260 1.31  LDD0285 
Muscleblind-like protein 3 (MBNL3) LDTP12630 1.17  LDD0285 
Myeloid-derived growth factor (MYDGF) LDTP10003 2.81  LDD0285 
Myosin regulatory light chain 12B (MYL12B) LDTP00487 0.05; 0.74  LDD0285 
Myotrophin (MTPN) LDTP04819 1.00  LDD0285 
N6-adenosine-methyltransferase non-catalytic subunit (METTL14) LDTP12234 1.15  LDD0285 
Nascent polypeptide-associated complex subunit alpha (NACA) LDTP05977 0.29  LDD0285 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 0.90  LDD0285 
Nuclear migration protein nudC (NUDC) LDTP13817 0.84  LDD0285 
Nucleolin (NCL) LDTP02990 1.16; 1.08; 0.99 ...  LDD0285 
Nucleolysin TIAR (TIAL1) LDTP05274 1.22  LDD0285 
Nucleophosmin (NPM1) LDTP02164 0.90; 1.04; 0.60  LDD0285 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 0.62; 2.37; 1.03  LDD0285 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 0.87; 1.03; 0.87  LDD0285 
Oxysterol-binding protein-related protein 11 (OSBPL11) LDTP11367 0.89  LDD0285 
Perilipin-3 (PLIN3) LDTP01021 0.86  LDD0285 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 1.14; 1.95; 0.92 ...  LDD0285 
Plastin-3 (PLS3) LDTP02692 0.80; 0.81  LDD0285 
Platelet-activating factor acetylhydrolase IB subunit beta (PAFAH1B1) LDTP04015 1.04; 0.93  LDD0285 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 1.07; 1.24; 1.03  LDD0285 
Poly(rC)-binding protein 2 (PCBP2) LDTP06367 0.86  LDD0285 
Polyadenylate-binding protein 1 (PABPC1) LDTP02595 0.89; 0.94; 0.93 ...  LDD0285 
Polyadenylate-binding protein 4 (PABPC4) LDTP05821 0.94; 0.59  LDD0285 
Polypyrimidine tract-binding protein 1 (PTBP1) LDTP03364 0.86; 1.01  LDD0285 
Prefoldin subunit 3 (VBP1) LDTP04935 1.43  LDD0285 
Prelamin-A/C (LMNA) LDTP01932 0.85; 0.89  LDD0285 
Profilin-1 (PFN1) LDTP02218 1.01; 1.14  LDD0285 
Programmed cell death protein 5 (PDCD5) LDTP00417 1.27; 1.33  LDD0285 
Proliferating cell nuclear antigen (PCNA) LDTP02596 1.51; 0.68  LDD0285 
Protein FAM118B (FAM118B) LDTP15852 1.21  LDD0285 
Protein flightless-1 homolog (FLII) LDTP05734 0.66  LDD0285 
Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) LDTP13656 1.25; 1.31; 1.00 ...  LDD0285 
Protein LSM12 (LSM12) LDTP06780 1.09  LDD0285 
Protein mago nashi homolog 2 (MAGOHB) LDTP10071 0.84  LDD0285 
Protein NipSnap homolog 3A (NIPSNAP3A) LDTP18525 1.28; 1.39  LDD0285 
Protein RCC2 (RCC2) LDTP13020 0.83  LDD0285 
Protein S100-A11 (S100A11) LDTP03620 1.13; 1.13  LDD0285 
Protein SET (SET) LDTP05277 1.76  LDD0285 
Protein SGT1 homolog (SUGT1) LDTP13935 0.67; 1.17  LDD0285 
Protein TFG (TFG) LDTP09851 1.32  LDD0285 
Protein transport protein Sec23A (SEC23A) LDTP06390 0.87  LDD0285 
Protein transport protein Sec23B (SEC23B) LDTP06391 0.75  LDD0285 
Putative protein FAM10A5 (ST13P5) LDTP17811 0.87  LDD0285 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 0.67  LDD0285 
Pyridoxal phosphate homeostasis protein (PLPBP) LDTP14521 10.44; 1.16  LDD0285 
Rab GDP dissociation inhibitor alpha (GDI1) LDTP03574 1.22; 0.91  LDD0285 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 0.92; 1.18; 1.23 ...  LDD0285 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 1.20  LDD0285 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 1.00; 1.47; 1.18 ...  LDD0285 
Reticulocalbin-1 (RCN1) LDTP06352 0.97  LDD0285 
Retinoblastoma-associated protein (RB1) LDTP02146 0.63  LDD0285 
Rho GDP-dissociation inhibitor 1 (ARHGDIA) LDTP04510 1.00; 1.01; 1.27 ...  LDD0285 
Rho guanine nucleotide exchange factor 2 (ARHGEF2) LDTP09950 0.58  LDD0285 
Ribosome biogenesis protein WDR12 (WDR12) LDTP11625 1.86  LDD0285 
RNA-binding protein 3 (RBM3) LDTP05226 0.94; 0.91  LDD0285 
RNA-binding protein EWS (EWSR1) LDTP05318 0.88  LDD0285 
RNA-binding protein FUS (FUS) LDTP03775 1.12; 0.92  LDD0285 
Serine/arginine-rich splicing factor 2 (SRSF2) LDTP05280 0.96  LDD0285 
Serine/arginine-rich splicing factor 8 (SRSF8) LDTP11117 0.96  LDD0285 
Serpin H1 (SERPINH1) LDTP04363 0.77  LDD0285 
Single-stranded DNA-binding protein, mitochondrial (SSBP1) LDTP05437 0.75; 1.19; 0.96 ...  LDD0285 
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) LDTP00862 0.88; 1.01; 0.91 ...  LDD0285 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 0.93; 0.40; 0.80  LDD0285 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 0.85; 0.90  LDD0285 
Small ribosomal subunit protein eS19 (RPS19) LDTP03864 0.96  LDD0285 
Small ribosomal subunit protein eS24 (RPS24) LDTP05012 0.69; 1.00; 0.81  LDD0285 
Small ribosomal subunit protein eS26 (RPS26) LDTP05014 0.54  LDD0285 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 0.51; 0.82  LDD0285 
Small ribosomal subunit protein eS4, Y isoform 1 (RPS4Y1) LDTP14653 0.82  LDD0285 
Small ribosomal subunit protein eS4, Y isoform 2 (RPS4Y2) LDTP19820 0.82  LDD0285 
Small ribosomal subunit protein eS7 (RPS7) LDTP04958 0.88  LDD0285 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 0.65; 0.70; 20.00 ...  LDD0285 
Small ribosomal subunit protein uS11 (RPS14) LDTP04970 0.78  LDD0285 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 0.44  LDD0285 
Small ribosomal subunit protein uS13 (RPS18) LDTP04972 0.82; 4.03; 1.28  LDD0285 
Small ribosomal subunit protein uS15 (RPS13) LDTP04974 0.93; 0.98; 0.88  LDD0285 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 0.75; 1.02  LDD0285 
Small ribosomal subunit protein uS2 (RPSA) LDTP02312 0.71  LDD0285 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 0.83; 1.13; 0.76  LDD0285 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 0.91; 0.94  LDD0285 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 0.86; 0.82  LDD0285 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 0.55  LDD0285 
Splicing factor YJU2 (YJU2) LDTP11317 1.22  LDD0285 
Src substrate cortactin (CTTN) LDTP06094 0.95; 0.76; 1.03 ...  LDD0285 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 1.01; 0.61; 0.38 ...  LDD0285 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 0.79; 2.42; 1.24 ...  LDD0285 
Stromal cell-derived factor 2-like protein 1 (SDF2L1) LDTP16047 0.93  LDD0285 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 0.96; 0.83  LDD0285 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 1.52  LDD0285 
Structural maintenance of chromosomes protein 4 (SMC4) LDTP12606 0.93  LDD0285 
T-complex protein 1 subunit beta (CCT2) LDTP05113 3.02; 2.09  LDD0285 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 0.97  LDD0285 
T-complex protein 1 subunit eta (CCT7) LDTP10990 0.21  LDD0285 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 0.82; 0.72  LDD0285 
T-complex protein 1 subunit theta (CCT8) LDTP04390 1.02; 0.47; 1.09 ...  LDD0285 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 0.77  LDD0285 
T-complex protein 1 subunit zeta-2 (CCT6B) LDTP09777 0.77  LDD0285 
Tetratricopeptide repeat protein 1 (TTC1) LDTP15840 1.08  LDD0285 
Tetratricopeptide repeat protein 4 (TTC4) LDTP01678 0.93  LDD0285 
Transcription elongation factor A protein 1 (TCEA1) LDTP03209 1.51  LDD0285 
Transcription elongation factor SPT6 (SUPT6H) LDTP07928 1.10  LDD0285 
Transgelin-2 (TAGLN2) LDTP03846 0.91; 0.94; 0.91  LDD0285 
Translationally-controlled tumor protein (TPT1) LDTP02683 1.86; 0.88  LDD0285 
Transmembrane glycoprotein NMB (GPNMB) LDTP06237 1.00  LDD0285 
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WDR6) LDTP12296 0.91  LDD0285 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 0.98  LDD0285 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 1.03  LDD0285 
Tubulin beta chain (TUBB) LDTP02205 0.87; 0.84; 0.83 ...  LDD0285 
Tubulin beta-2A chain (TUBB2A) LDTP05998 0.94; 0.89; 0.90 ...  LDD0285 
Tubulin beta-2B chain (TUBB2B) LDTP11277 0.80; 0.94; 0.89 ...  LDD0285 
Tubulin beta-3 chain (TUBB3) LDTP05904 0.87; 0.81; 0.85 ...  LDD0285 
Tubulin beta-4A chain (TUBB4A) LDTP02037 0.89; 0.86; 0.87 ...  LDD0285 
Tubulin beta-4B chain (TUBB4B) LDTP05076 0.51; 0.94; 0.89 ...  LDD0285 
Tubulin beta-6 chain (TUBB6) LDTP11233 0.91; 0.92; 0.93  LDD0285 
Tubulin gamma-1 chain (TUBG1) LDTP03213 1.34  LDD0285 
Tubulin gamma-2 chain (TUBG2) LDTP12512 1.34  LDD0285 
Tubulin-folding cofactor B (TBCB) LDTP10860 1.03; 0.98  LDD0285 
U6 snRNA-associated Sm-like protein LSm2 (LSM2) LDTP13946 0.99  LDD0285 
Ubiquilin-1 (UBQLN1) LDTP13626 0.85  LDD0285 
Ubiquitin-associated protein 2-like (UBAP2L) LDTP06060 0.50  LDD0285 
Ubiquitin-fold modifier 1 (UFM1) LDTP04946 1.15  LDD0285 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 1.04  LDD0285 
Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) LDTP11534 0.88  LDD0285 
Vacuolar fusion protein CCZ1 homolog (CCZ1) LDTP14797 1.52  LDD0285 
Vasodilator-stimulated phosphoprotein (VASP) LDTP04372 1.01  LDD0285 
Vimentin (VIM) LDTP02297 1.06; 0.82; 0.44 ...  LDD0285 
Vinculin (VCL) LDTP02946 0.51; 1.14  LDD0285 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 1.06  LDD0285 
WD repeat-containing protein 1 (WDR1) LDTP01118 1.03; 0.97; 0.87 ...  LDD0285 
WD repeat-containing protein 5 (WDR5) LDTP04948 0.87  LDD0285 
WW domain-binding protein 2 (WBP2) LDTP10033 1.13; 1.30  LDD0285 
Zyxin (ZYX) LDTP06507 1.21  LDD0285 
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Full Information of The Labelling Profiles of This Competitor

HHS-482
 Probe Info 
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 50 uM
Quantitative Method SILAC
Competitor Name JWB131
Competitor Concentration 50 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Skin
Disease Model Melanoma [ICD-11:2C82]
Model Name Human melanoma cell lysate (DM93)
Interaction Atlas ID  LDD0285  Download The Altas

References

1 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.