Details of the Target

General Information of Target

Target ID LDTP04241
Target Name Nuclear autoantigenic sperm protein (NASP)
Gene Name NASP
Gene ID 4678
Synonyms
Nuclear autoantigenic sperm protein; NASP
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAMESTATAAVAAELVSADKIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIP
AAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEG
EKTEDESLVENNDNIDEEAREELREQVYDAMGEKEEAKKTEDKSLAKPETDKEQDSEMEK
GGREDMDISKSAEEPQEKVDLTLDWLTETSEEAKGGAAPEGPNEAEVTSGKPEQEVPDAE
EEKSVSGTDVQEECREKGGQEKQGEVIVSIEEKPKEVSEEQPVVTLEKQGTAVEVEAESL
DPTVKPVDVGGDEPEEKVVTSENEAGKAVLEQLVGQEVPPAEESPEVTTEAAEASAVEAG
SEVSEKPGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSIERLTETKDGSGLEEKVRAKLVP
SQEETKLSVEESEAAGDGVDTKVAQGATEKSPEDKVQIAANEETQEREEQMKEGEETEGS
EEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLY
AAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQY
DEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQ
RSGNVAELALKATLVESSTSGFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKR
KPEEESPRKDDAKKAKQEPEVNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAG
ATVESTAC
Target Bioclass
Other
Family
NASP family
Subcellular location
Cytoplasm
Function
Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.
Uniprot ID
P49321
Ensemble ID
ENST00000350030.8
HGNC ID
HGNC:7644

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CCK81 Insertion: p.T160NfsTer10 DBIA    Probe Info 
HEC1 SNV: p.A460D DBIA    Probe Info 
MOLT4 SNV: p.A544T IA-alkyne    Probe Info 
NOMO1 Substitution: p.S480L DBIA    Probe Info 
SNGM SNV: p.L110V DBIA    Probe Info 
SW403 SNV: p.E322Ter DBIA    Probe Info 
TYKNU Deletion: p.F529_K530del DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 50 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
A-EBA
 Probe Info  		3.92  LDD0215  [2]
AZ-9
 Probe Info  		7.97  LDD0393  [3]
TG42
 Probe Info  		4.19  LDD0326  [4]
W1
 Probe Info  		66.18  LDD0235  [5]
FBP2
 Probe Info  		2.59  LDD0323  [6]
TH211
 Probe Info  		Y540(20.00); Y635(20.00); Y91(16.77); Y596(11.66)  LDD0257  [7]
TH214
 Probe Info  		Y540(17.73); Y635(13.66)  LDD0258  [7]
TH216
 Probe Info  		Y540(20.00); Y635(20.00); Y91(10.39)  LDD0259  [7]
ONAyne
 Probe Info  		N.A.  LDD0273  [8]
Probe 1
 Probe Info  		Y148(13.18); Y540(29.11); Y635(36.04)  LDD3495  [9]
AHL-Pu-1
 Probe Info  		C84(2.06); C254(10.11)  LDD0168  [10]
HHS-482
 Probe Info  		Y540(0.90)  LDD0285  [11]
HHS-475
 Probe Info  		Y600(0.44); Y635(0.79); Y540(0.96)  LDD0264  [12]
HHS-465
 Probe Info  		Y540(10.00); Y596(8.45); Y600(6.88); Y635(10.00)  LDD2237  [13]
DBIA
 Probe Info  		C708(0.97)  LDD0078  [14]
5E-2FA
 Probe Info  		N.A.  LDD2235  [15]
ATP probe
 Probe Info  		K698(0.00); K413(0.00); K262(0.00); K45(0.00)  LDD0199  [16]
4-Iodoacetamidophenylacetylene
 Probe Info  		C708(0.00); C84(0.00); C568(0.00); C254(0.00)  LDD0038  [17]
IA-alkyne
 Probe Info  		C568(0.00); C708(0.00); C84(0.00)  LDD0032  [18]
IPIAA_H
 Probe Info  		C568(0.00); C84(0.00)  LDD0030  [19]
IPIAA_L
 Probe Info  		C568(0.00); C708(0.00); C84(0.00)  LDD0031  [19]
Lodoacetamide azide
 Probe Info  		C708(0.00); C568(0.00); C254(0.00); C84(0.00)  LDD0037  [17]
BTD
 Probe Info  		C254(0.00); C708(0.00)  LDD0004  [20]
JW-RF-010
 Probe Info  		C708(0.00); C788(0.00); C84(0.00)  LDD0026  [21]
NAIA_4
 Probe Info  		C254(0.00); C708(0.00)  LDD2226  [22]
TFBX
 Probe Info  		C708(0.00); C84(0.00)  LDD0027  [21]
WYneN
 Probe Info  		N.A.  LDD0021  [20]
WYneO
 Probe Info  		N.A.  LDD0022  [20]
DA-P3
 Probe Info  		N.A.  LDD0178  [23]
aHNE
 Probe Info  		N.A.  LDD0001  [20]
1d-yne
 Probe Info  		K671(0.00); K231(0.00); K698(0.00)  LDD0356  [24]
Compound 10
 Probe Info  		C254(0.00); C708(0.00); C84(0.00)  LDD2216  [25]
Compound 11
 Probe Info  		C254(0.00); C708(0.00); C84(0.00)  LDD2213  [25]
ENE
 Probe Info  		C254(0.00); C708(0.00)  LDD0006  [20]
IPM
 Probe Info  		C254(0.00); C708(0.00)  LDD0005  [20]
NHS
 Probe Info  		K657(0.00); K636(0.00); K273(0.00); K643(0.00)  LDD0010  [20]
OSF
 Probe Info  		N.A.  LDD0029  [26]
PPMS
 Probe Info  		N.A.  LDD0008  [20]
SF
 Probe Info  		Y540(0.00); Y635(0.00); K636(0.00)  LDD0028  [26]
STPyne
 Probe Info  		N.A.  LDD0009  [20]
VSF
 Probe Info  		C254(0.00); C708(0.00)  LDD0007  [20]
Phosphinate-6
 Probe Info  		C254(0.00); C708(0.00)  LDD0018  [27]
Ox-W18
 Probe Info  		N.A.  LDD2175  [28]
1c-yne
 Probe Info  		K231(0.00); K626(0.00); K455(0.00); K698(0.00)  LDD0228  [24]
Acrolein
 Probe Info  		C708(0.00); C254(0.00); H714(0.00)  LDD0217  [29]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [29]
Methacrolein
 Probe Info  		C708(0.00); C254(0.00)  LDD0218  [29]
AOyne
 Probe Info  		13.60  LDD0443  [30]
NAIA_5
 Probe Info  		C254(0.00); C708(0.00); C84(0.00)  LDD2223  [22]
PAL-AfBPP Probe
Click To Hide/Show 18 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
ILS-1 PP
 Probe Info  		2.61  LDD0417  [31]
C040
 Probe Info  		10.56  LDD1740  [32]
C106
 Probe Info  		19.43  LDD1793  [32]
C211
 Probe Info  		9.58  LDD1885  [32]
C220
 Probe Info  		19.97  LDD1894  [32]
C242
 Probe Info  		5.50  LDD1915  [32]
C249
 Probe Info  		12.91  LDD1922  [32]
C354
 Probe Info  		7.16  LDD2015  [32]
C420
 Probe Info  		15.14  LDD2075  [32]
FFF probe11
 Probe Info  		11.02  LDD0471  [33]
FFF probe13
 Probe Info  		19.99  LDD0475  [33]
FFF probe14
 Probe Info  		16.23  LDD0477  [33]
FFF probe2
 Probe Info  		13.41  LDD0463  [33]
FFF probe3
 Probe Info  		7.13  LDD0464  [33]
JN0003
 Probe Info  		20.00  LDD0469  [33]
VE-P
 Probe Info  		N.A.  LDD0396  [34]
OEA-DA
 Probe Info  		3.17  LDD0046  [35]
STS-1
 Probe Info  		N.A.  LDD0068  [36]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C708(1.00); C254(0.90)  LDD2142  [37]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C708(0.78); C254(0.80)  LDD2112  [37]
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C254(0.83)  LDD2130  [37]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C708(0.94)  LDD2117  [37]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C708(1.05)  LDD2152  [37]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C708(1.11)  LDD2103  [37]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C708(0.43)  LDD2132  [37]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C708(0.81)  LDD2131  [37]
 LDCM0025  4SU-RNA HEK-293T C84(2.06); C254(10.11)  LDD0168  [10]
 LDCM0026  4SU-RNA+native RNA HEK-293T C708(2.06); C254(10.31)  LDD0169  [10]
 LDCM0214  AC1 HEK-293T C708(1.03); C84(1.00); C568(0.89); C254(1.15)  LDD1507  [38]
 LDCM0215  AC10 HEK-293T C708(0.94); C84(0.95); C568(1.01); C254(1.07)  LDD1508  [38]
 LDCM0226  AC11 HEK-293T C708(0.98); C84(1.09); C568(1.04); C254(0.91)  LDD1509  [38]
 LDCM0237  AC12 HEK-293T C708(0.98); C84(1.09); C568(1.11); C254(1.12)  LDD1510  [38]
 LDCM0259  AC14 HEK-293T C708(1.00); C84(1.08); C568(1.01); C254(0.97)  LDD1512  [38]
 LDCM0270  AC15 HEK-293T C708(0.98); C84(1.15); C568(1.13); C254(0.89)  LDD1513  [38]
 LDCM0276  AC17 HEK-293T C708(1.05); C84(1.10); C568(1.03); C254(0.96)  LDD1515  [38]
 LDCM0277  AC18 HEK-293T C708(1.00); C84(0.87); C568(1.08); C254(1.10)  LDD1516  [38]
 LDCM0278  AC19 HEK-293T C708(1.07); C84(1.12); C568(0.97); C254(0.83)  LDD1517  [38]
 LDCM0279  AC2 HEK-293T C708(0.98); C84(1.00); C568(0.93); C254(1.12)  LDD1518  [38]
 LDCM0280  AC20 HEK-293T C708(1.01); C84(1.12); C568(1.11); C254(1.13)  LDD1519  [38]
 LDCM0281  AC21 HEK-293T C708(1.03); C84(1.38); C568(1.26); C254(0.97)  LDD1520  [38]
 LDCM0282  AC22 HEK-293T C708(1.01); C84(1.20); C568(1.05); C254(1.04)  LDD1521  [38]
 LDCM0283  AC23 HEK-293T C708(1.00); C84(1.16); C568(1.01); C254(1.34)  LDD1522  [38]
 LDCM0284  AC24 HEK-293T C708(0.99); C84(1.25); C568(1.00); C254(1.18)  LDD1523  [38]
 LDCM0285  AC25 HEK-293T C708(0.97); C84(1.08); C568(0.99); C254(0.96)  LDD1524  [38]
 LDCM0286  AC26 HEK-293T C708(0.98); C84(1.07); C568(0.97); C254(1.10)  LDD1525  [38]
 LDCM0287  AC27 HEK-293T C708(0.96); C84(1.08); C568(1.02); C254(0.91)  LDD1526  [38]
 LDCM0288  AC28 HEK-293T C708(0.97); C84(1.11); C568(1.03); C254(0.85)  LDD1527  [38]
 LDCM0289  AC29 HEK-293T C708(0.96); C84(1.02); C568(1.05); C254(1.02)  LDD1528  [38]
 LDCM0290  AC3 HEK-293T C708(1.00); C84(1.00); C568(1.04); C254(0.88)  LDD1529  [38]
 LDCM0291  AC30 HEK-293T C708(1.00); C84(1.07); C568(1.12); C254(1.05)  LDD1530  [38]
 LDCM0292  AC31 HEK-293T C708(0.92); C84(1.10); C568(1.04); C254(1.01)  LDD1531  [38]
 LDCM0293  AC32 HEK-293T C708(0.97); C84(1.28); C568(0.93); C254(0.98)  LDD1532  [38]
 LDCM0294  AC33 HEK-293T C708(1.12); C84(1.10); C568(1.04); C254(1.10)  LDD1533  [38]
 LDCM0295  AC34 HEK-293T C708(0.88); C84(0.99); C568(1.19); C254(1.01)  LDD1534  [38]
 LDCM0296  AC35 HEK-293T C708(1.03); C84(1.19); C568(1.25); C254(0.93)  LDD1535  [38]
 LDCM0297  AC36 HEK-293T C708(0.98); C84(1.18); C568(1.12); C254(0.95)  LDD1536  [38]
 LDCM0298  AC37 HEK-293T C708(0.99); C84(1.32); C568(1.32); C254(0.89)  LDD1537  [38]
 LDCM0299  AC38 HEK-293T C708(1.00); C84(1.21); C568(1.13); C254(0.87)  LDD1538  [38]
 LDCM0300  AC39 HEK-293T C708(1.06); C84(1.24); C568(1.11); C254(0.83)  LDD1539  [38]
 LDCM0301  AC4 HEK-293T C708(0.98); C84(0.96); C568(1.27); C254(0.96)  LDD1540  [38]
 LDCM0302  AC40 HEK-293T C708(0.93); C84(1.25); C568(1.02); C254(0.83)  LDD1541  [38]
 LDCM0303  AC41 HEK-293T C708(1.07); C84(1.14); C568(0.91); C254(0.91)  LDD1542  [38]
 LDCM0304  AC42 HEK-293T C708(0.92); C84(0.96); C568(1.46); C254(0.98)  LDD1543  [38]
 LDCM0305  AC43 HEK-293T C708(0.96); C84(1.21); C568(1.08); C254(0.93)  LDD1544  [38]
 LDCM0306  AC44 HEK-293T C708(0.97); C84(1.25); C568(1.37); C254(0.87)  LDD1545  [38]
 LDCM0307  AC45 HEK-293T C708(0.97); C84(1.16); C568(1.03); C254(0.97)  LDD1546  [38]
 LDCM0308  AC46 HEK-293T C708(1.00); C84(1.17); C568(1.12); C254(0.94)  LDD1547  [38]
 LDCM0309  AC47 HEK-293T C708(1.05); C84(1.14); C568(1.20); C254(1.16)  LDD1548  [38]
 LDCM0310  AC48 HEK-293T C708(0.94); C84(1.06); C568(1.08); C254(1.04)  LDD1549  [38]
 LDCM0311  AC49 HEK-293T C708(1.04); C84(1.00); C568(0.98); C254(0.80)  LDD1550  [38]
 LDCM0312  AC5 HEK-293T C708(1.01); C84(1.04); C568(1.24); C254(0.95)  LDD1551  [38]
 LDCM0313  AC50 HEK-293T C708(0.99); C84(0.98); C568(1.00); C254(0.99)  LDD1552  [38]
 LDCM0314  AC51 HEK-293T C708(1.02); C84(1.11); C568(1.04); C254(0.91)  LDD1553  [38]
 LDCM0315  AC52 HEK-293T C708(1.01); C84(1.00); C568(1.28); C254(1.04)  LDD1554  [38]
 LDCM0316  AC53 HEK-293T C708(1.02); C84(1.07); C568(1.22); C254(1.00)  LDD1555  [38]
 LDCM0317  AC54 HEK-293T C708(0.99); C84(1.12); C568(1.13); C254(0.99)  LDD1556  [38]
 LDCM0318  AC55 HEK-293T C708(1.02); C84(1.25); C568(0.93); C254(0.98)  LDD1557  [38]
 LDCM0319  AC56 HEK-293T C708(0.98); C84(1.14); C568(0.98); C254(1.04)  LDD1558  [38]
 LDCM0320  AC57 HEK-293T C708(1.07); C84(0.88); C568(0.95); C254(1.02)  LDD1559  [38]
 LDCM0321  AC58 HEK-293T C708(0.91); C84(1.01); C568(1.04); C254(1.13)  LDD1560  [38]
 LDCM0322  AC59 HEK-293T C708(0.91); C84(1.20); C568(1.24); C254(0.91)  LDD1561  [38]
 LDCM0323  AC6 HEK-293T C708(1.00); C84(1.01); C568(0.97); C254(0.84)  LDD1562  [38]
 LDCM0324  AC60 HEK-293T C708(0.94); C84(1.00); C568(1.24); C254(1.07)  LDD1563  [38]
 LDCM0325  AC61 HEK-293T C708(0.98); C84(1.14); C568(1.17); C254(0.94)  LDD1564  [38]
 LDCM0326  AC62 HEK-293T C708(0.96); C84(1.16); C568(1.10); C254(1.00)  LDD1565  [38]
 LDCM0327  AC63 HEK-293T C708(1.03); C84(1.07); C568(1.06); C254(0.94)  LDD1566  [38]
 LDCM0328  AC64 HEK-293T C708(0.91); C84(1.10); C568(1.06); C254(0.95)  LDD1567  [38]
 LDCM0334  AC7 HEK-293T C708(1.01); C84(1.05); C568(1.22); C254(1.14)  LDD1568  [38]
 LDCM0345  AC8 HEK-293T C708(0.89); C84(1.07); C568(1.11); C254(0.85)  LDD1569  [38]
 LDCM0520  AKOS000195272 MDA-MB-231 C708(0.95)  LDD2113  [37]
 LDCM0248  AKOS034007472 HEK-293T C708(0.99); C84(1.17); C568(1.11); C254(0.87)  LDD1511  [38]
 LDCM0356  AKOS034007680 HEK-293T C708(1.00); C84(1.03); C568(0.96); C254(1.04)  LDD1570  [38]
 LDCM0275  AKOS034007705 HEK-293T C708(0.94); C84(1.09); C568(1.00); C254(0.86)  LDD1514  [38]
 LDCM0156  Aniline NCI-H1299 12.26  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C708(0.97)  LDD0078  [14]
 LDCM0498  BS-3668 MDA-MB-231 C708(0.64); C254(0.38)  LDD2091  [37]
 LDCM0630  CCW28-3 231MFP C708(1.00)  LDD2214  [39]
 LDCM0108  Chloroacetamide HeLa C708(0.00); C254(0.00); H714(0.00)  LDD0222  [29]
 LDCM0632  CL-Sc Hep-G2 C254(1.80); C708(1.68); C708(0.87); C254(0.80)  LDD2227  [22]
 LDCM0367  CL1 HEK-293T C708(0.97); C84(1.03); C568(0.28)  LDD1571  [38]
 LDCM0368  CL10 HEK-293T C708(1.08); C84(0.86); C568(1.07); C254(0.57)  LDD1572  [38]
 LDCM0369  CL100 HEK-293T C708(1.00); C84(0.82); C568(0.98); C254(0.83)  LDD1573  [38]
 LDCM0370  CL101 HEK-293T C708(0.98); C84(1.05); C568(0.92)  LDD1574  [38]
 LDCM0371  CL102 HEK-293T C708(0.93); C84(0.99); C568(0.87); C254(1.19)  LDD1575  [38]
 LDCM0372  CL103 HEK-293T C708(0.98); C84(1.13); C568(0.98); C254(0.90)  LDD1576  [38]
 LDCM0373  CL104 HEK-293T C708(0.99); C84(1.08); C568(0.99); C254(1.01)  LDD1577  [38]
 LDCM0374  CL105 HEK-293T C708(1.06); C84(1.18); C568(1.00)  LDD1578  [38]
 LDCM0375  CL106 HEK-293T C708(0.99); C84(1.04); C568(1.09); C254(0.84)  LDD1579  [38]
 LDCM0376  CL107 HEK-293T C708(1.09); C84(1.05); C568(1.09); C254(0.95)  LDD1580  [38]
 LDCM0377  CL108 HEK-293T C708(0.98); C84(1.00); C568(0.84); C254(0.95)  LDD1581  [38]
 LDCM0378  CL109 HEK-293T C708(0.98); C84(1.07); C568(0.96)  LDD1582  [38]
 LDCM0379  CL11 HEK-293T C708(1.18); C84(1.13); C568(1.15); C254(0.36)  LDD1583  [38]
 LDCM0380  CL110 HEK-293T C708(0.91); C84(0.94); C568(1.02); C254(0.82)  LDD1584  [38]
 LDCM0381  CL111 HEK-293T C708(0.97); C84(0.91); C568(0.92); C254(0.86)  LDD1585  [38]
 LDCM0382  CL112 HEK-293T C708(1.12); C84(0.95); C568(0.79); C254(0.90)  LDD1586  [38]
 LDCM0383  CL113 HEK-293T C708(1.01); C84(1.07); C568(1.00)  LDD1587  [38]
 LDCM0384  CL114 HEK-293T C708(0.92); C84(0.91); C568(0.80); C254(0.58)  LDD1588  [38]
 LDCM0385  CL115 HEK-293T C708(0.99); C84(0.88); C568(1.00); C254(0.79)  LDD1589  [38]
 LDCM0386  CL116 HEK-293T C708(1.05); C84(1.02); C568(1.04); C254(0.88)  LDD1590  [38]
 LDCM0387  CL117 HEK-293T C708(0.98); C84(1.04); C568(0.97)  LDD1591  [38]
 LDCM0388  CL118 HEK-293T C708(0.91); C84(0.99); C568(1.13); C254(0.99)  LDD1592  [38]
 LDCM0389  CL119 HEK-293T C708(0.95); C84(0.94); C568(0.96); C254(0.93)  LDD1593  [38]
 LDCM0390  CL12 HEK-293T C708(0.98); C84(1.24); C568(1.08); C254(0.96)  LDD1594  [38]
 LDCM0391  CL120 HEK-293T C708(0.96); C84(1.01); C568(1.09); C254(0.95)  LDD1595  [38]
 LDCM0392  CL121 HEK-293T C708(1.05); C84(1.08); C568(0.95)  LDD1596  [38]
 LDCM0393  CL122 HEK-293T C708(0.95); C84(1.04); C568(1.18); C254(0.77)  LDD1597  [38]
 LDCM0394  CL123 HEK-293T C708(0.85); C84(0.91); C568(0.79); C254(0.81)  LDD1598  [38]
 LDCM0395  CL124 HEK-293T C708(0.96); C84(0.94); C568(0.94); C254(0.81)  LDD1599  [38]
 LDCM0396  CL125 HEK-293T C708(0.92); C84(0.96); C568(1.10)  LDD1600  [38]
 LDCM0397  CL126 HEK-293T C708(0.87); C84(1.02); C568(0.97); C254(0.79)  LDD1601  [38]
 LDCM0398  CL127 HEK-293T C708(0.89); C84(1.05); C568(1.01); C254(0.94)  LDD1602  [38]
 LDCM0399  CL128 HEK-293T C708(0.97); C84(0.98); C568(1.13); C254(0.80)  LDD1603  [38]
 LDCM0400  CL13 HEK-293T C708(1.05); C84(0.99); C568(1.08)  LDD1604  [38]
 LDCM0401  CL14 HEK-293T C708(0.94); C84(1.01); C568(0.98); C254(0.61)  LDD1605  [38]
 LDCM0402  CL15 HEK-293T C708(0.84); C84(0.83); C568(0.85); C254(0.75)  LDD1606  [38]
 LDCM0403  CL16 HEK-293T C708(1.02); C84(1.11); C568(1.02); C254(1.02)  LDD1607  [38]
 LDCM0404  CL17 HEK-293T C708(1.08); C84(0.95); C568(0.87); C254(0.66)  LDD1608  [38]
 LDCM0405  CL18 HEK-293T C708(0.94); C84(1.07); C568(1.06); C254(1.02)  LDD1609  [38]
 LDCM0406  CL19 HEK-293T C708(1.11); C84(1.34); C568(1.09); C254(0.90)  LDD1610  [38]
 LDCM0407  CL2 HEK-293T C708(1.01); C84(1.02); C568(0.89); C254(0.86)  LDD1611  [38]
 LDCM0408  CL20 HEK-293T C708(1.10); C84(0.58); C568(1.11); C254(1.05)  LDD1612  [38]
 LDCM0409  CL21 HEK-293T C708(1.01); C84(1.34); C568(0.91); C254(0.91)  LDD1613  [38]
 LDCM0410  CL22 HEK-293T C708(1.13); C84(1.06); C568(1.09); C254(0.61)  LDD1614  [38]
 LDCM0411  CL23 HEK-293T C708(1.13); C84(1.32); C568(1.15); C254(0.26)  LDD1615  [38]
 LDCM0412  CL24 HEK-293T C708(0.98); C84(1.25); C568(1.09); C254(1.15)  LDD1616  [38]
 LDCM0413  CL25 HEK-293T C708(0.97); C84(1.06); C568(1.04)  LDD1617  [38]
 LDCM0414  CL26 HEK-293T C708(1.06); C84(1.22); C568(1.19); C254(0.93)  LDD1618  [38]
 LDCM0415  CL27 HEK-293T C708(1.03); C84(0.97); C568(1.05); C254(0.98)  LDD1619  [38]
 LDCM0416  CL28 HEK-293T C708(1.00); C84(0.96); C568(0.96); C254(0.97)  LDD1620  [38]
 LDCM0417  CL29 HEK-293T C708(0.99); C84(1.15); C568(0.88); C254(1.04)  LDD1621  [38]
 LDCM0418  CL3 HEK-293T C708(1.01); C84(0.91); C568(1.02); C254(0.81)  LDD1622  [38]
 LDCM0419  CL30 HEK-293T C708(1.04); C84(1.18); C568(0.97); C254(1.07)  LDD1623  [38]
 LDCM0420  CL31 HEK-293T C708(0.99); C84(1.11); C568(1.08); C254(0.94)  LDD1624  [38]
 LDCM0421  CL32 HEK-293T C708(1.10); C84(0.66); C568(1.19); C254(1.25)  LDD1625  [38]
 LDCM0422  CL33 HEK-293T C708(0.89); C84(1.15); C568(0.94); C254(0.71)  LDD1626  [38]
 LDCM0423  CL34 HEK-293T C708(1.07); C84(1.06); C568(1.17); C254(0.65)  LDD1627  [38]
 LDCM0424  CL35 HEK-293T C708(1.11); C84(1.33); C568(1.19); C254(0.19)  LDD1628  [38]
 LDCM0425  CL36 HEK-293T C708(0.97); C84(1.22); C568(1.12); C254(0.96)  LDD1629  [38]
 LDCM0426  CL37 HEK-293T C708(0.97); C84(1.28); C568(0.96)  LDD1630  [38]
 LDCM0428  CL39 HEK-293T C708(1.04); C84(1.09); C568(0.94); C254(0.91)  LDD1632  [38]
 LDCM0429  CL4 HEK-293T C708(1.02); C84(0.96); C568(0.88); C254(0.75)  LDD1633  [38]
 LDCM0430  CL40 HEK-293T C708(1.07); C84(1.03); C568(1.01); C254(0.88)  LDD1634  [38]
 LDCM0431  CL41 HEK-293T C708(0.97); C84(1.11); C568(0.94); C254(0.98)  LDD1635  [38]
 LDCM0432  CL42 HEK-293T C708(0.97); C84(1.19); C568(1.14); C254(1.15)  LDD1636  [38]
 LDCM0433  CL43 HEK-293T C708(0.93); C84(1.31); C568(1.08); C254(0.96)  LDD1637  [38]
 LDCM0434  CL44 HEK-293T C708(1.07); C84(0.74); C568(1.18); C254(1.20)  LDD1638  [38]
 LDCM0435  CL45 HEK-293T C708(1.02); C84(1.26); C568(1.07); C254(1.02)  LDD1639  [38]
 LDCM0436  CL46 HEK-293T C708(1.07); C84(1.05); C568(1.19); C254(0.70)  LDD1640  [38]
 LDCM0437  CL47 HEK-293T C708(1.09); C84(1.22); C568(1.13); C254(0.24)  LDD1641  [38]
 LDCM0438  CL48 HEK-293T C708(0.95); C84(1.24); C568(1.01); C254(0.85)  LDD1642  [38]
 LDCM0439  CL49 HEK-293T C708(0.99); C84(1.07); C568(1.08)  LDD1643  [38]
 LDCM0440  CL5 HEK-293T C708(1.17); C84(1.04); C568(0.97); C254(0.95)  LDD1644  [38]
 LDCM0441  CL50 HEK-293T C708(0.99); C84(1.06); C568(0.96); C254(0.94)  LDD1645  [38]
 LDCM0443  CL52 HEK-293T C708(1.03); C84(0.88); C568(0.93); C254(0.92)  LDD1646  [38]
 LDCM0444  CL53 HEK-293T C708(1.00); C84(0.98); C568(0.83); C254(0.81)  LDD1647  [38]
 LDCM0445  CL54 HEK-293T C708(0.88); C84(1.02); C568(0.71); C254(0.82)  LDD1648  [38]
 LDCM0446  CL55 HEK-293T C708(1.05); C84(1.20); C568(1.13); C254(0.87)  LDD1649  [38]
 LDCM0447  CL56 HEK-293T C708(1.02); C84(0.71); C568(1.07); C254(1.24)  LDD1650  [38]
 LDCM0448  CL57 HEK-293T C708(1.05); C84(1.31); C568(0.82); C254(0.86)  LDD1651  [38]
 LDCM0449  CL58 HEK-293T C708(1.03); C84(1.08); C568(1.03); C254(0.64)  LDD1652  [38]
 LDCM0450  CL59 HEK-293T C708(1.11); C84(1.27); C568(1.04); C254(0.40)  LDD1653  [38]
 LDCM0451  CL6 HEK-293T C708(0.92); C84(0.92); C568(1.04); C254(0.89)  LDD1654  [38]
 LDCM0452  CL60 HEK-293T C708(0.99); C84(1.23); C568(1.07); C254(1.01)  LDD1655  [38]
 LDCM0453  CL61 HEK-293T C708(0.97); C84(1.05); C568(0.94)  LDD1656  [38]
 LDCM0454  CL62 HEK-293T C708(0.93); C84(1.05); C568(1.09); C254(0.88)  LDD1657  [38]
 LDCM0455  CL63 HEK-293T C708(0.97); C84(1.00); C568(1.05); C254(1.01)  LDD1658  [38]
 LDCM0456  CL64 HEK-293T C708(1.00); C84(0.99); C568(1.02); C254(0.75)  LDD1659  [38]
 LDCM0457  CL65 HEK-293T C708(1.22); C84(1.13); C568(1.03); C254(1.24)  LDD1660  [38]
 LDCM0458  CL66 HEK-293T C708(1.03); C84(1.05); C568(1.10); C254(1.03)  LDD1661  [38]
 LDCM0459  CL67 HEK-293T C708(1.00); C84(1.13); C568(1.30); C254(0.88)  LDD1662  [38]
 LDCM0460  CL68 HEK-293T C708(1.02); C84(0.82); C568(1.21); C254(1.32)  LDD1663  [38]
 LDCM0461  CL69 HEK-293T C708(1.01); C84(1.31); C568(1.13); C254(0.90)  LDD1664  [38]
 LDCM0462  CL7 HEK-293T C708(1.08); C84(1.02); C568(0.99); C254(0.81)  LDD1665  [38]
 LDCM0463  CL70 HEK-293T C708(1.06); C84(1.13); C568(1.30); C254(0.88)  LDD1666  [38]
 LDCM0464  CL71 HEK-293T C708(1.13); C84(1.27); C568(1.20); C254(0.52)  LDD1667  [38]
 LDCM0465  CL72 HEK-293T C708(1.02); C84(1.52); C568(1.02); C254(1.10)  LDD1668  [38]
 LDCM0466  CL73 HEK-293T C708(1.01); C84(0.92); C568(0.93)  LDD1669  [38]
 LDCM0467  CL74 HEK-293T C708(0.96); C84(1.12); C568(1.09); C254(0.86)  LDD1670  [38]
 LDCM0469  CL76 HEK-293T C708(1.04); C84(0.94); C568(0.93); C254(0.93)  LDD1672  [38]
 LDCM0470  CL77 HEK-293T C708(0.97); C84(0.97); C568(1.02); C254(0.91)  LDD1673  [38]
 LDCM0471  CL78 HEK-293T C708(0.96); C84(1.08); C568(1.10); C254(0.91)  LDD1674  [38]
 LDCM0472  CL79 HEK-293T C708(0.94); C84(1.08); C568(1.02); C254(0.88)  LDD1675  [38]
 LDCM0473  CL8 HEK-293T C708(0.84); C84(0.63); C568(1.25); C254(0.81)  LDD1676  [38]
 LDCM0474  CL80 HEK-293T C708(1.04); C84(0.79); C568(1.32); C254(1.38)  LDD1677  [38]
 LDCM0475  CL81 HEK-293T C708(1.01); C84(1.33); C568(0.92); C254(1.00)  LDD1678  [38]
 LDCM0476  CL82 HEK-293T C708(0.99); C84(1.08); C568(1.10); C254(0.89)  LDD1679  [38]
 LDCM0477  CL83 HEK-293T C708(1.07); C84(1.16); C568(0.96); C254(0.75)  LDD1680  [38]
 LDCM0478  CL84 HEK-293T C708(0.90); C84(1.11); C568(1.14); C254(0.93)  LDD1681  [38]
 LDCM0479  CL85 HEK-293T C708(0.90); C84(1.00); C568(1.03)  LDD1682  [38]
 LDCM0480  CL86 HEK-293T C708(0.92); C84(1.29); C568(1.20); C254(0.75)  LDD1683  [38]
 LDCM0481  CL87 HEK-293T C708(0.95); C84(1.04); C568(0.66); C254(0.94)  LDD1684  [38]
 LDCM0482  CL88 HEK-293T C708(0.98); C84(1.10); C568(1.06); C254(0.84)  LDD1685  [38]
 LDCM0483  CL89 HEK-293T C708(1.04); C84(1.10); C568(1.06); C254(0.98)  LDD1686  [38]
 LDCM0484  CL9 HEK-293T C708(1.00); C84(1.09); C568(1.19); C254(0.85)  LDD1687  [38]
 LDCM0485  CL90 HEK-293T C708(0.81); C84(0.90); C568(0.87); C254(0.79)  LDD1688  [38]
 LDCM0486  CL91 HEK-293T C708(1.00); C84(1.15); C568(1.01); C254(0.93)  LDD1689  [38]
 LDCM0487  CL92 HEK-293T C708(0.99); C84(0.94); C568(1.18); C254(0.95)  LDD1690  [38]
 LDCM0488  CL93 HEK-293T C708(0.99); C84(1.16); C568(0.80); C254(0.90)  LDD1691  [38]
 LDCM0489  CL94 HEK-293T C708(1.09); C84(1.13); C568(1.06); C254(0.93)  LDD1692  [38]
 LDCM0490  CL95 HEK-293T C708(0.95); C84(1.09); C568(1.09); C254(0.98)  LDD1693  [38]
 LDCM0491  CL96 HEK-293T C708(0.84); C84(1.00); C568(0.96); C254(0.82)  LDD1694  [38]
 LDCM0492  CL97 HEK-293T C708(0.94); C84(0.94); C568(1.00)  LDD1695  [38]
 LDCM0493  CL98 HEK-293T C708(0.98); C84(0.91); C568(1.01); C254(0.65)  LDD1696  [38]
 LDCM0494  CL99 HEK-293T C708(0.96); C84(0.88); C568(0.87); C254(0.84)  LDD1697  [38]
 LDCM0185  Compound 17 HEK-293T 4.07  LDD0512  [33]
 LDCM0191  Compound 21 HEK-293T 3.50  LDD0508  [33]
 LDCM0190  Compound 34 HEK-293T 3.11  LDD0510  [33]
 LDCM0193  Compound 36 HEK-293T 3.48  LDD0511  [33]
 LDCM0634  CY-0357 Hep-G2 C254(1.42); C708(0.55)  LDD2228  [22]
 LDCM0495  E2913 HEK-293T C708(1.03); C84(1.17); C568(1.06); C254(0.87)  LDD1698  [38]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C708(1.35)  LDD1702  [37]
 LDCM0625  F8 Ramos C84(0.77); C708(1.56); C788(0.42)  LDD2187  [40]
 LDCM0572  Fragment10 Ramos C84(0.99); C708(0.73)  LDD2189  [40]
 LDCM0573  Fragment11 Ramos C84(0.04); C708(0.41)  LDD2190  [40]
 LDCM0574  Fragment12 Ramos C84(1.22); C708(0.67)  LDD2191  [40]
 LDCM0575  Fragment13 Ramos C84(1.00); C708(1.01)  LDD2192  [40]
 LDCM0576  Fragment14 Ramos C84(0.77); C708(0.93); C788(0.66)  LDD2193  [40]
 LDCM0579  Fragment20 Ramos C84(1.50); C708(0.51)  LDD2194  [40]
 LDCM0580  Fragment21 Ramos C84(1.35); C708(0.77)  LDD2195  [40]
 LDCM0582  Fragment23 Ramos C84(0.98); C708(0.97)  LDD2196  [40]
 LDCM0578  Fragment27 Ramos C84(0.95); C708(1.74)  LDD2197  [40]
 LDCM0586  Fragment28 Ramos C84(0.57); C708(1.22)  LDD2198  [40]
 LDCM0588  Fragment30 Ramos C84(0.65); C708(1.30)  LDD2199  [40]
 LDCM0589  Fragment31 Ramos C84(0.80); C708(0.87)  LDD2200  [40]
 LDCM0590  Fragment32 Ramos C84(0.74); C708(0.92)  LDD2201  [40]
 LDCM0468  Fragment33 HEK-293T C708(0.85); C84(1.02); C568(1.18); C254(0.80)  LDD1671  [38]
 LDCM0596  Fragment38 Ramos C84(1.04); C708(1.68)  LDD2203  [40]
 LDCM0566  Fragment4 Ramos C84(0.69); C708(0.75); C788(0.42)  LDD2184  [40]
 LDCM0427  Fragment51 HEK-293T C708(0.94); C84(1.09); C568(1.01); C254(0.75)  LDD1631  [38]
 LDCM0610  Fragment52 Ramos C84(0.61); C708(1.23)  LDD2204  [40]
 LDCM0614  Fragment56 Ramos C84(0.99); C708(1.25)  LDD2205  [40]
 LDCM0569  Fragment7 Ramos C84(1.21); C708(0.86); C788(0.93)  LDD2186  [40]
 LDCM0571  Fragment9 Ramos C84(1.83); C708(0.52)  LDD2188  [40]
 LDCM0116  HHS-0101 DM93 Y600(0.44); Y635(0.79); Y540(0.96)  LDD0264  [12]
 LDCM0117  HHS-0201 DM93 Y600(0.61); Y540(0.81); Y635(0.95)  LDD0265  [12]
 LDCM0118  HHS-0301 DM93 Y600(0.25); Y635(0.73); Y540(0.88)  LDD0266  [12]
 LDCM0119  HHS-0401 DM93 Y600(0.71); Y540(0.85); Y635(1.02)  LDD0267  [12]
 LDCM0120  HHS-0701 DM93 Y600(0.69); Y540(0.88); Y635(0.90)  LDD0268  [12]
 LDCM0107  IAA HeLa N.A.  LDD0221  [29]
 LDCM0123  JWB131 DM93 Y540(0.90)  LDD0285  [11]
 LDCM0124  JWB142 DM93 Y540(0.49); Y600(0.55)  LDD0286  [11]
 LDCM0125  JWB146 DM93 Y540(0.93); Y600(0.99)  LDD0287  [11]
 LDCM0126  JWB150 DM93 Y540(2.97); Y600(1.47)  LDD0288  [11]
 LDCM0127  JWB152 DM93 Y540(2.19); Y600(1.23)  LDD0289  [11]
 LDCM0128  JWB198 DM93 Y540(1.13); Y600(1.19)  LDD0290  [11]
 LDCM0129  JWB202 DM93 Y540(0.48); Y600(0.31)  LDD0291  [11]
 LDCM0130  JWB211 DM93 Y540(0.90); Y600(0.53)  LDD0292  [11]
 LDCM0022  KB02 HEK-293T C708(0.97); C84(0.99); C568(1.32); C254(1.21)  LDD1492  [38]
 LDCM0023  KB03 HEK-293T C708(1.03); C84(0.92); C568(0.87); C254(1.28)  LDD1497  [38]
 LDCM0024  KB05 COLO792 C710(1.16); C86(1.52)  LDD3310  [41]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C708(1.22); C254(0.99)  LDD2102  [37]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C708(0.48)  LDD2121  [37]
 LDCM0109  NEM HeLa H714(0.00); H53(0.00); H545(0.00)  LDD0223  [29]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C708(1.26); C254(1.03)  LDD2090  [37]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C708(0.77)  LDD2092  [37]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C708(1.03)  LDD2093  [37]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C708(0.91)  LDD2094  [37]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C708(0.80); C254(0.38)  LDD2096  [37]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C708(0.86)  LDD2097  [37]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C708(0.74); C254(1.65)  LDD2098  [37]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C708(0.76)  LDD2099  [37]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C708(0.72); C254(1.04)  LDD2100  [37]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C708(1.27)  LDD2101  [37]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C708(0.62); C254(1.00)  LDD2104  [37]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C708(1.23)  LDD2105  [37]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C708(0.55); C254(1.02)  LDD2106  [37]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C708(0.80)  LDD2107  [37]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C708(1.27); C254(0.53)  LDD2108  [37]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C708(0.95)  LDD2109  [37]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C708(1.25)  LDD2110  [37]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C708(0.60)  LDD2111  [37]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C708(0.64); C254(0.86)  LDD2114  [37]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C708(0.50)  LDD2115  [37]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C708(0.95)  LDD2116  [37]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C708(0.99); C254(0.41)  LDD2118  [37]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C708(0.84)  LDD2120  [37]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C708(1.01)  LDD2122  [37]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C708(0.95)  LDD2123  [37]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C708(1.06); C254(0.38)  LDD2124  [37]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C708(0.91); C254(1.09)  LDD2125  [37]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C708(0.95); C254(0.36)  LDD2126  [37]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C708(1.01)  LDD2127  [37]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C708(0.86)  LDD2128  [37]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C708(0.93)  LDD2129  [37]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C708(1.13)  LDD2133  [37]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C708(0.49)  LDD2134  [37]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C708(0.99)  LDD2135  [37]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C708(1.07)  LDD2136  [37]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C708(0.97)  LDD1700  [37]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C708(0.69)  LDD2140  [37]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C708(0.87); C254(1.00)  LDD2141  [37]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C708(0.97)  LDD2143  [37]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C708(0.96)  LDD2146  [37]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C708(2.59)  LDD2147  [37]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C708(0.59)  LDD2148  [37]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C708(1.10); C254(0.59)  LDD2149  [37]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C708(0.55); C254(0.35)  LDD2150  [37]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C708(1.11)  LDD2151  [37]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C708(1.63); C254(1.27)  LDD2153  [37]
 LDCM0627  NUDT7-COV-1 HEK-293T C708(0.54)  LDD2206  [42]
 LDCM0628  OTUB2-COV-1 HEK-293T C708(0.62)  LDD2207  [42]
 LDCM0131  RA190 MM1.R C708(1.48); C84(1.34); C788(1.06)  LDD0304  [43]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Telomeric repeat-binding factor 2-interacting protein 1 (TERF2IP) RAP1 family Q9NYB0
Other
Click To Hide/Show 6 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Histone chaperone ASF1A (ASF1A) ASF1 family Q9Y294
Histone H3.1 (H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3C10; H3C11; H3C12) Histone H3 family P68431
Histone H3.1t (H3-4) Histone H3 family Q16695
Histone H3.2 (H3C15; H3C14; H3C13) Histone H3 family Q71DI3
Histone H3.3 (H3-3A; H3-3B) Histone H3 family P84243
Histone H3.3C (H3-5) Histone H3 family Q6NXT2

References

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Mass spectrometry data entry: PXD037665
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Mass spectrometry data entry: PXD010277
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Mass spectrometry data entry: PXD018580
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Mass spectrometry data entry: PXD028270
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Mass spectrometry data entry: PXD044625
11 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
12 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
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15 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
16 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
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Mass spectrometry data entry: PXD028853
18 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
19 SP3-Enabled Rapid and High Coverage Chemoproteomic Identification of Cell-State-Dependent Redox-Sensitive Cysteines. Mol Cell Proteomics. 2022 Apr;21(4):100218. doi: 10.1016/j.mcpro.2022.100218. Epub 2022 Feb 25.
Mass spectrometry data entry: PXD029500 , PXD031647
20 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD029255
22 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
23 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348
24 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
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Mass spectrometry data entry: PXD022279
26 Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529022. doi: 10.1101/2023.02.17.529022.
Mass spectrometry data entry: PXD039931
27 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
28 Oxidative cyclization reagents reveal tryptophan cation- interactions. Nature. 2024 Mar;627(8004):680-687. doi: 10.1038/s41586-024-07140-6. Epub 2024 Mar 6.
Mass spectrometry data entry: PXD001377 , PXD005252
29 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
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31 A Chemical Proteomic Analysis of Illudin-Interacting Proteins. Chemistry. 2019 Sep 25;25(54):12644-12651. doi: 10.1002/chem.201902919. Epub 2019 Sep 3.
Mass spectrometry data entry: PXD014175
32 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD007570
36 Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probe. Chem Commun (Camb). 2011 Oct 28;47(40):11306-8. doi: 10.1039/c1cc14824a. Epub 2011 Sep 16.
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Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD044402
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Mass spectrometry data entry: PXD027578
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Mass spectrometry data entry: PXD047840
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