Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0125
Competitor Name
JWB146
Synonyms
SCHEMBL22558315; AOPCAXFJCOMUKR-UHFFFAOYSA-N; 1-Cyclopropylsulfonyl-3-[4-(trifluoromethyl)phenyl]-1,2,4-triazole
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 317.29
Lipid-water partition coefficient (xlogp) 2.8
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C12H10F3N3O2S
IUPAC Name
1-cyclopropylsulfonyl-3-[4-(trifluoromethyl)phenyl]-1,2,4-triazole
Canonical SMILES
C1CC1S(=O)(=O)N2C=NC(=N2)C3=CC=C(C=C3)C(F)(F)F
InChI
InChI=1S/C12H10F3N3O2S/c13-12(14,15)9-3-1-8(2-4-9)11-16-7-18(17-11)21(19,20)10-5-6-10/h1-4,7,10H,5-6H2
InChIKey
AOPCAXFJCOMUKR-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
HHS-482
 Probe Info  		50 uM Human melanoma cell lysate (DM93) [1]

Target(s) List of this Competitor

297 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
(3R)-3-hydroxyacyl-CoA dehydrogenase (HSD17B8) LDTP09770 1.58  LDD0287 
1,4-alpha-glucan-branching enzyme (GBE1) LDTP05419 1.69  LDD0287 
14 kDa phosphohistidine phosphatase (PHPT1) LDTP12543 1.02; 0.83  LDD0287 
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) LDTP02356 0.96  LDD0287 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 0.33; 1.20  LDD0287 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 0.97  LDD0287 
26S proteasome non-ATPase regulatory subunit 3 (PSMD3) LDTP00714 1.05  LDD0287 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 1.10  LDD0287 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 1.00  LDD0287 
26S proteasome regulatory subunit 7 (PSMC2) LDTP03797 0.14  LDD0287 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 1.03  LDD0287 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 6.68  LDD0287 
5'-3' exoribonuclease 2 (XRN2) LDTP11701 1.04  LDD0287 
6-phosphogluconate dehydrogenase, decarboxylating (PGD) LDTP04499 0.68  LDD0287 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 0.95; 1.20; 1.34 ...  LDD0287 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 1.66  LDD0287 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 1.01  LDD0287 
Acetyl-CoA carboxylase 1 (ACACA) LDTP05742 0.63  LDD0287 
Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) LDTP12463 0.80  LDD0287 
Actin, alpha cardiac muscle 1 (ACTC1) LDTP05069 1.00  LDD0287 
Actin, cytoplasmic 1 (ACTB) LDTP04876 0.93; 0.86; 0.79 ...  LDD0287 
Acylamino-acid-releasing enzyme (APEH) LDTP02693 0.41  LDD0287 
Adenosylhomocysteinase (AHCY) LDTP03242 0.93; 1.75  LDD0287 
Adenylosuccinate synthetase isozyme 2 (ADSS2) LDTP03541 0.88  LDD0287 
ADP-ribose pyrophosphatase, mitochondrial (NUDT9) LDTP11318 0.88  LDD0287 
ADP-ribosylation factor 1 (ARF1) LDTP05192 1.05; 0.87; 0.64  LDD0287 
ADP-ribosylation factor 3 (ARF3) LDTP04907 1.05; 0.87; 0.64  LDD0287 
ADP-ribosylation factor 4 (ARF4) LDTP02942 1.05; 0.87  LDD0287 
ADP-ribosylation factor 5 (ARF5) LDTP05193 1.05; 0.87  LDD0287 
ADP-sugar pyrophosphatase (NUDT5) LDTP13462 1.17  LDD0287 
Aflatoxin B1 aldehyde reductase member 2 (AKR7A2) LDTP00776 1.09; 0.76; 1.10 ...  LDD0287 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 1.05; 0.43  LDD0287 
Alcohol dehydrogenase class-3 (ADH5) LDTP02587 1.38; 0.98; 1.44  LDD0287 
Aldo-keto reductase family 1 member A1 (AKR1A1) LDTP02729 1.22  LDD0287 
Alpha-aminoadipic semialdehyde synthase, mitochondrial (AASS) LDTP13186 0.91; 0.43; 1.62  LDD0287 
Alpha-enolase (ENO1) LDTP02159 0.99; 0.98; 2.91 ...  LDD0287 
Amidophosphoribosyltransferase (PPAT) LDTP05480 1.17  LDD0287 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 0.12; 1.24  LDD0287 
Asparagine synthetase [glutamine-hydrolyzing] (ASNS) LDTP02264 20.00; 0.92  LDD0287 
Asparagine--tRNA ligase, cytoplasmic (NARS1) LDTP00866 1.07; 1.03; 0.61  LDD0287 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 5.27; 1.07; 1.49  LDD0287 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 5.89; 0.89; 1.37  LDD0287 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 1.01; 2.04  LDD0287 
ATP-citrate synthase (ACLY) LDTP04561 1.32; 2.06; 1.26 ...  LDD0287 
ATP-dependent 6-phosphofructokinase, liver type (PFKL) LDTP02925 1.32  LDD0287 
ATP-dependent 6-phosphofructokinase, muscle type (PFKM) LDTP02261 0.74  LDD0287 
ATP-dependent RNA helicase A (DHX9) LDTP05550 1.56  LDD0287 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 1.34  LDD0287 
ATPase MORC2 (MORC2) LDTP14308 2.85  LDD0287 
Aurora kinase B (AURKB) LDTP10346 0.48  LDD0287 
Bifunctional coenzyme A synthase (COASY) LDTP05736 1.10  LDD0287 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 1.82; 1.02  LDD0287 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 1.96  LDD0287 
Biliverdin reductase A (BLVRA) LDTP04552 1.65  LDD0287 
Biotinidase (BTD) LDTP04030 1.27  LDD0287 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 1.00; 0.76; 1.31 ...  LDD0287 
Calcyclin-binding protein (CACYBP) LDTP12163 1.52; 1.27; 1.22  LDD0287 
Carbonyl reductase [NADPH] 1 (CBR1) LDTP02831 2.35  LDD0287 
Carbonyl reductase [NADPH] 3 (CBR3) LDTP01321 1.10  LDD0287 
Casein kinase II subunit beta (CSNK2B) LDTP05067 0.55  LDD0287 
Catalase (CAT) LDTP02001 1.62  LDD0287 
Cathepsin B (CTSB) LDTP02223 0.98; 0.97; 1.05 ...  LDD0287 
Cathepsin D (CTSD) LDTP02198 1.37; 1.17  LDD0287 
Cathepsin Z (CTSZ) LDTP13147 0.98; 1.56; 1.62 ...  LDD0287 
Citrate synthase, mitochondrial (CS) LDTP01205 0.74; 1.00; 0.97  LDD0287 
Cleavage and polyadenylation specificity factor subunit 5 (NUDT21) LDTP00873 1.16  LDD0287 
CTP synthase 1 (CTPS1) LDTP02922 1.06; 1.24; 1.09  LDD0287 
Cyclin-dependent kinase 1 (CDK1) LDTP02149 0.96; 1.32; 1.09 ...  LDD0287 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 0.96; 1.09; 2.99  LDD0287 
Cystathionine gamma-lyase (CTH) LDTP03656 0.81  LDD0287 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 2.12  LDD0287 
Cytochrome c oxidase assembly factor 7 (COA7) LDTP10137 0.88  LDD0287 
Cytoglobin (CYGB) LDTP09656 1.29; 1.00  LDD0287 
Cytosol aminopeptidase (LAP3) LDTP03455 1.15  LDD0287 
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 2.57; 0.94  LDD0287 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 3.26  LDD0287 
Dehydrogenase/reductase SDR family member 11 (DHRS11) LDTP07678 1.20  LDD0287 
Dihydropteridine reductase (QDPR) LDTP02342 0.56  LDD0287 
Dipeptidyl peptidase 3 (DPP3) LDTP12803 1.24  LDD0287 
DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 0.90  LDD0287 
DNA replication licensing factor MCM2 (MCM2) LDTP04286 1.24  LDD0287 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 2.61  LDD0287 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 1.39  LDD0287 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 0.05  LDD0287 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 0.70  LDD0287 
DNA replication licensing factor MCM7 (MCM7) LDTP03682 1.00  LDD0287 
Dual specificity protein phosphatase 23 (DUSP23) LDTP11289 1.25  LDD0287 
Dual specificity protein phosphatase 3 (DUSP3) LDTP04415 0.86  LDD0287 
Dynamin-1-like protein (DNM1L) LDTP00273 1.09  LDD0287 
E3 ubiquitin-protein ligase ARIH2 (ARIH2) LDTP01575 0.91  LDD0287 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 0.99  LDD0287 
E3 ubiquitin-protein ligase UBR4 (UBR4) LDTP07118 1.13  LDD0287 
EH domain-containing protein 4 (EHD4) LDTP11788 1.20  LDD0287 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 1.01; 1.00; 0.97 ...  LDD0287 
Elongation factor 2 (EEF2) LDTP02672 2.17; 0.82; 1.74 ...  LDD0287 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 0.86; 0.61; 0.97  LDD0287 
Endoplasmic reticulum chaperone BiP (HSPA5) LDTP02534 5.08; 0.65; 0.59 ...  LDD0287 
Enoyl-CoA hydratase, mitochondrial (ECHS1) LDTP03518 1.27  LDD0287 
ERO1-like protein alpha (ERO1A) LDTP10386 1.56; 3.66  LDD0287 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 0.95; 1.16; 1.09 ...  LDD0287 
Eukaryotic initiation factor 4A-II (EIF4A2) LDTP06089 1.10; 1.36; 0.87  LDD0293 
Eukaryotic initiation factor 4A-III (EIF4A3) LDTP03861 0.85  LDD0287 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 1.04  LDD0287 
Exosome complex exonuclease RRP44 (DIS3) LDTP13887 1.16  LDD0287 
Farnesyl pyrophosphate synthase (FDPS) LDTP02721 0.83  LDD0287 
Fatty acid CoA ligase Acsl3 (ACSL3) LDTP01634 2.29; 0.76  LDD0287 
Fatty acid synthase (FASN) LDTP04243 1.42; 0.91; 0.92 ...  LDD0287 
Flap endonuclease 1 (FEN1) LDTP03872 0.99  LDD0287 
Fructose-2,6-bisphosphatase TIGAR (TIGAR) LDTP12405 1.16  LDD0287 
Fructose-bisphosphate aldolase A (ALDOA) LDTP02008 0.97; 0.97; 0.82 ...  LDD0287 
Fumarate hydratase, mitochondrial (FH) LDTP02235 1.15  LDD0287 
Fumarylacetoacetase (FAH) LDTP02868 2.42  LDD0287 
Galactokinase (GALK1) LDTP04424 1.44  LDD0287 
Gamma-enolase (ENO2) LDTP02328 0.92; 0.91  LDD0287 
GDP-mannose 4,6 dehydratase (GMDS) LDTP00999 1.07  LDD0287 
Geranylgeranyl transferase type-2 subunit beta (RABGGTB) LDTP04569 1.55  LDD0287 
Glucosamine-6-phosphate isomerase 1 (GNPDA1) LDTP04113 1.28  LDD0287 
Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 1.20; 0.22  LDD0287 
Glucose-6-phosphate isomerase (GPI) LDTP02162 0.42; 1.11; 0.65  LDD0287 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) LDTP05481 1.10; 0.94  LDD0287 
Glutaredoxin-1 (GLRX) LDTP03786 0.89  LDD0287 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 3.25; 1.79  LDD0287 
Glutathione S-transferase A4 (GSTA4) LDTP00575 4.21  LDD0287 
Glutathione S-transferase kappa 1 (GSTK1) LDTP13900 1.28  LDD0287 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 0.83  LDD0287 
Glutathione S-transferase P (GSTP1) LDTP02333 0.64; 1.02; 0.80 ...  LDD0287 
Glutathione synthetase (GSS) LDTP04200 1.35; 0.92  LDD0287 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 1.05; 1.27; 1.35 ...  LDD0287 
Glycine--tRNA ligase (GARS1) LDTP03946 1.11; 1.16; 3.02 ...  LDD0287 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 0.83; 1.07; 0.86 ...  LDD0287 
Glycogen phosphorylase, liver form (PYGL) LDTP02161 0.98  LDD0287 
Glycogen synthase kinase-3 alpha (GSK3A) LDTP04318 2.37  LDD0287 
Glycogen synthase kinase-3 beta (GSK3B) LDTP04319 2.37  LDD0287 
GTP-binding nuclear protein Ran (RAN) LDTP05007 1.25; 0.91; 1.13 ...  LDD0287 
HBS1-like protein (HBS1L) LDTP14019 2.25  LDD0287 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 0.99; 0.58; 1.23 ...  LDD0287 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 0.91; 0.98; 1.08 ...  LDD0287 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 0.73  LDD0287 
Histone deacetylase 1 (HDAC1) LDTP05918 1.06  LDD0287 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 1.44  LDD0287 
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL) LDTP03794 2.21  LDD0287 
Inorganic pyrophosphatase (PPA1) LDTP14854 0.68; 0.85; 1.27 ...  LDD0287 
Inorganic pyrophosphatase 2, mitochondrial (PPA2) LDTP11842 0.89  LDD0287 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 0.77; 1.17; 1.29 ...  LDD0287 
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) LDTP11700 1.27  LDD0287 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 1.29; 0.96; 0.45 ...  LDD0287 
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A) LDTP04345 1.26  LDD0287 
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (IDH3B) LDTP00885 1.41  LDD0287 
Isoleucine--tRNA ligase, cytoplasmic (IARS1) LDTP03947 1.37  LDD0287 
Kynurenine--oxoglutarate transaminase 3 (KYAT3) LDTP07763 0.34; 0.62  LDD0287 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 0.88; 0.96; 1.04 ...  LDD0287 
L-lactate dehydrogenase B chain (LDHB) LDTP02179 0.86; 1.08; 0.93 ...  LDD0287 
L-xylulose reductase (DCXR) LDTP08082 2.43  LDD0287 
Lactoylglutathione lyase (GLO1) LDTP05434 1.32  LDD0287 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 3.44  LDD0287 
Low molecular weight phosphotyrosine protein phosphatase (ACP1) LDTP03289 1.82; 1.81  LDD0287 
Lymphokine-activated killer T-cell-originated protein kinase (PBK) LDTP10500 1.03; 1.35; 1.27  LDD0287 
Lysosomal protective protein (CTSA) LDTP02505 0.95  LDD0287 
Macrophage migration inhibitory factor (MIF) LDTP02713 1.10; 0.96; 1.17 ...  LDD0287 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 0.85; 1.01  LDD0287 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 0.67; 0.58; 0.85 ...  LDD0287 
Mannose-1-phosphate guanyltransferase beta (GMPPB) LDTP14141 1.07  LDD0287 
MAP kinase-activated protein kinase 3 (MAPKAPK3) LDTP06589 0.51; 1.04  LDD0287 
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) LDTP02565 0.73; 1.15; 0.52  LDD0287 
Methionine adenosyltransferase 2 subunit beta (MAT2B) LDTP12915 0.46  LDD0287 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 0.96  LDD0287 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 2.47  LDD0287 
Methylthioribulose-1-phosphate dehydratase (APIP) LDTP10368 0.61  LDD0287 
Mitogen-activated protein kinase 1 (MAPK1) LDTP03445 0.85; 1.19  LDD0287 
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) LDTP01005 1.30; 1.01  LDD0287 
Myosin-10 (MYH10) LDTP03765 0.68; 1.42; 1.00 ...  LDD0287 
Myosin-9 (MYH9) LDTP03764 0.97; 1.20; 0.69 ...  LDD0287 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 0.94  LDD0287 
NAD(P)H dehydrogenase [quinone] 1 (NQO1) LDTP02798 1.17; 0.81; 1.28  LDD0287 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 0.82  LDD0287 
NEDD8-activating enzyme E1 regulatory subunit (NAE1) LDTP05925 0.83  LDD0287 
NEDD8-conjugating enzyme Ubc12 (UBE2M) LDTP04898 0.66  LDD0287 
Neutral alpha-glucosidase AB (GANAB) LDTP06192 0.95; 0.89  LDD0287 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 2.38  LDD0287 
Nucleoside diphosphate kinase B (NME2) LDTP03169 0.93  LDD0287 
Omega-amidase NIT2 (NIT2) LDTP12428 0.91; 1.23; 0.53 ...  LDD0287 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 1.28; 2.60; 1.30  LDD0287 
Palmitoyltransferase ZDHHC17 (ZDHHC17) LDTP08456 0.44  LDD0287 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 0.93; 1.01  LDD0287 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 1.08  LDD0287 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 1.16; 1.44  LDD0287 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 0.49; 1.73; 0.90  LDD0287 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) LDTP05912 1.06  LDD0287 
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3) LDTP11823 1.41  LDD0287 
Peroxiredoxin-1 (PRDX1) LDTP05503 0.91; 1.24; 0.85  LDD0287 
Peroxiredoxin-4 (PRDX4) LDTP05773 1.78; 1.07  LDD0287 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 1.29  LDD0287 
Phosphatidylinositide phosphatase SAC2 (INPP5F) LDTP13867 1.24  LDD0287 
Phosphoglucomutase-1 (PGM1) LDTP03818 1.72  LDD0287 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 1.07; 0.87; 1.00 ...  LDD0287 
Phosphoglycerate mutase 1 (PGAM1) LDTP02963 0.67; 1.71; 0.96 ...  LDD0287 
Phosphoserine aminotransferase (PSAT1) LDTP14198 1.31; 0.86; 0.87 ...  LDD0287 
Poly(A) polymerase alpha (PAPOLA) LDTP04394 1.78  LDD0287 
Probable 18S rRNA (guanine-N(7))-methyltransferase (BUD23) LDTP00845 1.56  LDD0287 
Probable aminopeptidase NPEPL1 (NPEPL1) LDTP09126 0.97  LDD0287 
Probable E3 ubiquitin-protein ligase IRF2BPL (IRF2BPL) LDTP11759 0.62; 0.77  LDD0287 
Prolyl endopeptidase (PREP) LDTP04163 0.74  LDD0287 
Prostaglandin reductase 1 (PTGR1) LDTP06227 1.68; 2.92; 2.01  LDD0287 
Prostaglandin reductase 2 (PTGR2) LDTP08979 1.90; 2.56; 2.24  LDD0287 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 0.95; 0.90  LDD0287 
Proteasome subunit alpha type-2 (PSMA2) LDTP03331 1.08; 1.10; 0.98  LDD0287 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 1.24; 1.13; 0.81 ...  LDD0287 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 1.05; 1.03; 0.60 ...  LDD0287 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 1.73; 1.57  LDD0287 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 1.12; 1.25  LDD0287 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 1.48; 0.98  LDD0287 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 1.19; 0.98  LDD0287 
Protein disulfide-isomerase (P4HB) LDTP02188 3.27; 0.72; 0.94 ...  LDD0287 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 0.94; 0.82; 0.96 ...  LDD0287 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 1.51; 1.13; 2.23  LDD0287 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 1.31  LDD0287 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 1.55  LDD0287 
Protein kinase C delta type (PRKCD) LDTP05461 1.48  LDD0287 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 1.37  LDD0287 
Putative elongation factor 1-alpha-like 3 (EEF1A1P5) LDTP15029 1.01; 1.00; 0.96 ...  LDD0287 
Pyridoxine-5'-phosphate oxidase (PNPO) LDTP12691 0.94  LDD0287 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 0.50; 0.05  LDD0287 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 1.10; 0.47; 0.97 ...  LDD0287 
Pyruvate kinase PKM (PKM) LDTP02733 0.54; 1.04; 0.98 ...  LDD0287 
Queuine tRNA-ribosyltransferase catalytic subunit 1 (QTRT1) LDTP11400 0.71  LDD0287 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 3.61; 0.85  LDD0287 
RAC-gamma serine/threonine-protein kinase (AKT3) LDTP13799 1.79; 0.85  LDD0287 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 1.00  LDD0287 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 0.90  LDD0287 
Ribonucleoside-diphosphate reductase large subunit (RRM1) LDTP03259 0.84  LDD0287 
RING finger and CHY zinc finger domain-containing protein 1 (RCHY1) LDTP10686 1.16  LDD0287 
RNA demethylase ALKBH5 (ALKBH5) LDTP07547 1.44  LDD0287 
RNA-splicing ligase RtcB homolog (RTCB) LDTP13992 2.70  LDD0287 
RuvB-like 1 (RUVBL1) LDTP13816 1.01  LDD0287 
S-adenosylmethionine synthase isoform type-2 (MAT2A) LDTP03577 1.33; 0.99  LDD0287 
S-formylglutathione hydrolase (ESD) LDTP02521 1.31; 0.80  LDD0287 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 0.53  LDD0287 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 1.84  LDD0287 
Sepiapterin reductase (SPR) LDTP03730 1.02; 1.42  LDD0287 
Septin-2 (SEPTIN2) LDTP06279 1.38; 2.48  LDD0287 
Septin-7 (SEPTIN7) LDTP06513 0.94; 0.93  LDD0287 
Septin-9 (SEPTIN9) LDTP13272 0.79; 1.77; 0.67  LDD0287 
Serine hydroxymethyltransferase, cytosolic (SHMT1) LDTP03688 1.33  LDD0287 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 0.54  LDD0287 
Serine/threonine-protein kinase PAK 2 (PAK2) LDTP05776 1.15  LDD0287 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 1.46  LDD0287 
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) LDTP05064 1.61; 0.69  LDD0287 
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB) LDTP04998 1.49  LDD0287 
Serine/threonine-protein phosphatase 4 catalytic subunit (PPP4C) LDTP04870 1.61  LDD0287 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 0.96  LDD0287 
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) LDTP04959 1.06; 1.11  LDD0287 
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) LDTP04960 1.06; 1.11  LDD0287 
Sialic acid synthase (NANS) LDTP12473 0.95; 1.08; 1.39  LDD0287 
Spermidine synthase (SRM) LDTP03008 1.06  LDD0287 
Spliceosome RNA helicase DDX39B (DDX39B) LDTP05991 0.72  LDD0287 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 1.05; 1.26  LDD0287 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 3.45  LDD0287 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 2.09  LDD0287 
SUMO-activating enzyme subunit 2 (UBA2) LDTP13156 0.91; 1.25  LDD0287 
SUMO-conjugating enzyme UBC9 (UBE2I) LDTP05062 1.10  LDD0287 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 1.24; 1.04; 2.32  LDD0287 
Thimet oligopeptidase (THOP1) LDTP04542 1.71  LDD0287 
Thioredoxin domain-containing protein 12 (TXNDC12) LDTP01707 0.88  LDD0287 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 0.88; 1.05; 0.95 ...  LDD0287 
Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) LDTP03515 0.48  LDD0287 
Threonine--tRNA ligase 1, cytoplasmic (TARS1) LDTP03365 0.72; 0.93; 0.99 ...  LDD0287 
Thymidylate kinase (DTYMK) LDTP03258 1.38; 0.96  LDD0287 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 0.83; 1.09; 0.93 ...  LDD0287 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 1.28  LDD0287 
Transketolase (TKT) LDTP03487 1.32; 0.97; 0.96 ...  LDD0287 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 1.12  LDD0287 
Triosephosphate isomerase (TPI1) LDTP04851 2.27; 1.67; 1.02  LDD0287 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 1.24  LDD0287 
Tryptophan--tRNA ligase, cytoplasmic (WARS1) LDTP03222 0.99; 0.39; 0.58 ...  LDD0287 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 1.12; 1.13; 1.08 ...  LDD0287 
Tubulin alpha-1B chain (TUBA1B) LDTP05074 1.12; 1.13; 1.08 ...  LDD0287 
Tubulin alpha-1C chain (TUBA1C) LDTP11074 1.16  LDD0287 
Tubulin--tyrosine ligase-like protein 12 (TTLL12) LDTP06067 0.71; 0.45  LDD0287 
Tyrosine--tRNA ligase, cytoplasmic (YARS1) LDTP04617 0.67; 0.89  LDD0287 
Tyrosine-protein kinase CSK (CSK) LDTP03944 1.03  LDD0287 
Ubiquitin carboxyl-terminal hydrolase 14 (USP14) LDTP04618 0.58  LDD0287 
Ubiquitin carboxyl-terminal hydrolase 39 (USP39) LDTP06903 0.90  LDD0287 
Ubiquitin-conjugating enzyme E2 N (UBE2N) LDTP04900 1.62; 3.96; 1.39  LDD0287 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 0.95; 1.09; 4.00  LDD0287 
UDP-glucose 4-epimerase (GALE) LDTP06111 1.13  LDD0287 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 1.07; 0.51; 1.07 ...  LDD0287 
UMP-CMP kinase (CMPK1) LDTP03519 0.90  LDD0287 
Unconventional myosin-Ie (MYO1E) LDTP05708 5.02  LDD0287 
Uridine 5'-monophosphate synthase (UMPS) LDTP02548 1.13  LDD0287 
Uridine phosphorylase 1 (UPP1) LDTP06643 1.30; 1.00; 0.80 ...  LDD0287 
Uroporphyrinogen decarboxylase (UROD) LDTP02135 1.29; 0.95  LDD0287 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 0.67; 1.18; 1.37  LDD0287 
V-type proton ATPase subunit E 2 (ATP6V1E2) LDTP15684 0.81  LDD0287 
Valine--tRNA ligase (VARS1) LDTP03366 0.71  LDD0287 
WD repeat-containing protein 82 (WDR82) LDTP07715 0.91  LDD0287 
Xaa-Pro aminopeptidase 1 (XPNPEP1) LDTP12444 1.20; 0.96  LDD0287 
Xaa-Pro dipeptidase (PEPD) LDTP02639 2.26  LDD0287 
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⏷ Show the Full List of 297 Enzyme
42 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein epsilon (YWHAE) LDTP04969 0.80; 1.10; 1.13 ...  LDD0287 
14-3-3 protein gamma (YWHAG) LDTP04953 1.00  LDD0287 
14-3-3 protein theta (YWHAQ) LDTP03385 1.17; 0.72  LDD0287 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 0.63; 0.97; 1.34 ...  LDD0287 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 0.71; 1.36  LDD0287 
Alpha-crystallin B chain (CRYAB) LDTP01929 2.37  LDD0287 
Alpha-synuclein (SNCA) LDTP03848 2.29  LDD0287 
Annexin A2 (ANXA2) LDTP02199 0.90; 1.01; 0.25 ...  LDD0287 
Annexin A5 (ANXA5) LDTP02307 0.82; 0.69; 0.94 ...  LDD0287 
Annexin A6 (ANXA6) LDTP02247 0.76; 1.10  LDD0287 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 2.13  LDD0287 
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 0.76; 1.44  LDD0287 
Calreticulin (CALR) LDTP03402 0.95; 0.99; 0.86 ...  LDD0287 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 1.05; 0.83; 0.88 ...  LDD0287 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 0.96; 0.65; 1.11 ...  LDD0287 
Clathrin heavy chain 1 (CLTC) LDTP05252 0.45; 1.06  LDD0287 
Copine-3 (CPNE3) LDTP01133 1.12; 1.11  LDD0287 
Cystatin-B (CSTB) LDTP02009 1.06; 1.24; 1.04  LDD0287 
Dihydropyrimidinase-related protein 2 (DPYSL2) LDTP06554 0.38; 0.75; 0.88  LDD0287 
Eukaryotic translation initiation factor 5A-1 (EIF5A) LDTP05056 1.37; 1.28  LDD0287 
Exportin-1 (XPO1) LDTP00501 0.97; 0.72  LDD0287 
Exportin-2 (CSE1L) LDTP04662 1.34  LDD0287 
Filamin-A (FLNA) LDTP03107 1.30; 0.93  LDD0287 
Galectin-3 (LGALS3) LDTP02929 0.91  LDD0287 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 0.70; 1.02; 1.09 ...  LDD0287 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 0.72  LDD0287 
Importin subunit beta-1 (KPNB1) LDTP06242 1.10  LDD0287 
mRNA export factor RAE1 (RAE1) LDTP05122 1.47  LDD0287 
Protein SEC13 homolog (SEC13) LDTP04707 1.81  LDD0287 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 1.23; 0.46  LDD0287 
Sorting nexin-2 (SNX2) LDTP01043 0.25  LDD0287 
T-complex protein 1 subunit delta (CCT4) LDTP04391 0.58; 1.25; 0.84 ...  LDD0287 
Talin-1 (TLN1) LDTP14031 0.70; 0.52; 0.84 ...  LDD0287 
Thioredoxin domain-containing protein 17 (TXNDC17) LDTP11103 0.85; 0.86; 1.16  LDD0287 
Transferrin receptor protein 1 (TFRC) LDTP01969 1.42  LDD0287 
Ubiquilin-4 (UBQLN4) LDTP12533 1.10  LDD0287 
V-type proton ATPase subunit B, brain isoform (ATP6V1B2) LDTP03104 4.21; 0.98  LDD0287 
V-type proton ATPase subunit C 1 (ATP6V1C1) LDTP03105 0.85  LDD0287 
V-type proton ATPase subunit E 1 (ATP6V1E1) LDTP03811 0.81  LDD0287 
V-type proton ATPase subunit G 1 (ATP6V1G1) LDTP01185 1.01  LDD0287 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 0.96  LDD0287 
Voltage-gated potassium channel subunit beta-2 (KCNAB2) LDTP05817 0.79  LDD0287 
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⏷ Show the Full List of 42 Transporter and channel
8 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
High mobility group protein B1 (HMGB1) LDTP02343 0.85; 0.54; 0.54 ...  LDD0287 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 0.90  LDD0287 
Nascent polypeptide-associated complex subunit alpha, muscle-specific form (NACA) LDTP14411 0.09  LDD0287 
Signal transducer and activator of transcription 3 (STAT3) LDTP03903 2.61  LDD0287 
Signal transducer and activator of transcription 5A (STAT5A) LDTP03971 0.82  LDD0287 
Transcription factor SOX-10 (SOX10) LDTP04752 0.87; 0.52  LDD0287 
Transcription factor SOX-9 (SOX9) LDTP04179 1.00  LDD0287 
Y-box-binding protein 1 (YBX1) LDTP05065 1.56; 1.87; 0.88  LDD0287 
------------------------------------------------------------------------------------
⏷ Show the Full List of 8 Transcription factor
277 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
10 kDa heat shock protein, mitochondrial (HSPE1) LDTP04931 2.34  LDD0287 
14-3-3 protein beta/alpha (YWHAB) LDTP03617 0.96; 0.88  LDD0287 
14-3-3 protein eta (YWHAH) LDTP05442 0.32  LDD0287 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 0.73  LDD0287 
Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) LDTP03871 0.72  LDD0287 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 0.64  LDD0287 
Actin nucleation-promoting factor WASL (WASL) LDTP00263 0.77  LDD0287 
Actin-related protein 3 (ACTR3) LDTP04902 1.07; 1.23; 0.55 ...  LDD0287 
Adapter molecule crk (CRK) LDTP04091 1.05; 1.11; 1.40  LDD0287 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 0.42; 0.94; 1.13  LDD0287 
AH receptor-interacting protein (AIP) LDTP00202 0.78  LDD0287 
Alpha-actinin-1 (ACTN1) LDTP02631 0.71; 0.74; 0.99  LDD0287 
Alpha-centractin (ACTR1A) LDTP04904 0.79  LDD0287 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 1.22  LDD0287 
Anamorsin (CIAPIN1) LDTP07385 0.52  LDD0287 
Ankyrin repeat and MYND domain-containing protein 2 (ANKMY2) LDTP17620 1.33  LDD0287 
Ankyrin repeat domain-containing protein 39 (ANKRD39) LDTP19320 1.47  LDD0287 
Annexin A3 (ANXA3) LDTP02620 0.87  LDD0287 
Annexin A7 (ANXA7) LDTP03030 0.94  LDD0287 
Apoptosis inhibitor 5 (API5) LDTP11575 1.01  LDD0287 
Bifunctional purine biosynthesis protein ATIC (ATIC) LDTP03612 2.09; 0.92; 1.39 ...  LDD0287 
Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (ARFGEF2) LDTP14237 0.96  LDD0287 
C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9) LDTP00934 0.93; 0.85  LDD0287 
Calpain small subunit 1 (CAPNS1) LDTP02047 0.98  LDD0287 
Calponin-3 (CNN3) LDTP06383 0.90; 0.90; 1.04 ...  LDD0287 
Calumenin (CALU) LDTP00887 1.00; 0.90; 0.94 ...  LDD0287 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 1.07; 1.10; 0.90 ...  LDD0287 
Cell cycle and apoptosis regulator protein 2 (CCAR2) LDTP08760 1.04  LDD0287 
Coatomer subunit alpha (COPA) LDTP04571 0.86  LDD0287 
Coatomer subunit beta (COPB1) LDTP04570 1.03  LDD0287 
Coatomer subunit gamma-1 (COPG1) LDTP14216 1.17  LDD0287 
Cofilin-1 (CFL1) LDTP03244 0.75; 0.92; 0.97 ...  LDD0287 
Cofilin-2 (CFL2) LDTP13827 0.57; 0.55  LDD0293 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 1.40  LDD0287 
Condensin complex subunit 2 (NCAPH) LDTP06268 1.12  LDD0287 
Copper transport protein ATOX1 (ATOX1) LDTP00229 0.95  LDD0287 
Coronin-1B (CORO1B) LDTP11101 1.00  LDD0287 
Coronin-1C (CORO1C) LDTP13580 0.84  LDD0287 
Crk-like protein (CRKL) LDTP04092 1.47; 0.75  LDD0287 
Cysteine and glycine-rich protein 1 (CSRP1) LDTP03106 0.97; 0.76; 0.92  LDD0287 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 1.52; 0.44; 0.74 ...  LDD0287 
Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2) LDTP05855 1.35  LDD0287 
Cytoplasmic FMR1-interacting protein 1 (CYFIP1) LDTP07958 1.10  LDD0287 
Cytotoxic granule associated RNA binding protein TIA1 (TIA1) LDTP03598 1.28  LDD0287 
Destrin (DSTN) LDTP04887 0.66; 0.51  LDD0287 
DnaJ homolog subfamily A member 2 (DNAJA2) LDTP01073 1.00  LDD0287 
DnaJ homolog subfamily B member 1 (DNAJB1) LDTP03325 0.84  LDD0287 
DnaJ homolog subfamily C member 3 (DNAJC3) LDTP05789 1.00  LDD0287 
DnaJ homolog subfamily C member 8 (DNAJC8) LDTP01361 1.59  LDD0287 
Drebrin-like protein (DBNL) LDTP13399 0.92; 0.97; 0.99  LDD0287 
Dynactin subunit 1 (DCTN1) LDTP06082 0.62  LDD0287 
Dynactin subunit 2 (DCTN2) LDTP05922 1.16  LDD0287 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 0.90  LDD0287 
Dynein light chain 2, cytoplasmic (DYNLL2) LDTP10308 0.87  LDD0287 
Elongation factor 1-beta (EEF1B2) LDTP03283 0.89; 0.85; 0.83 ...  LDD0287 
Elongation factor 1-delta (EEF1D) LDTP03499 0.93; 0.91; 1.14 ...  LDD0287 
Elongation factor 1-gamma (EEF1G) LDTP03367 1.59; 1.23; 1.15  LDD0287 
Endoplasmic reticulum resident protein 29 (ERP29) LDTP03509 1.25; 1.11  LDD0287 
Endoplasmin (HSP90B1) LDTP02734 0.92; 1.26; 1.45 ...  LDD0287 
Enhancer of mRNA-decapping protein 3 (EDC3) LDTP10299 2.32  LDD0287 
Epidermal growth factor receptor substrate 15-like 1 (EPS15L1) LDTP13097 1.91  LDD0287 
Eukaryotic translation initiation factor 1 (EIF1) LDTP03953 1.03  LDD0287 
Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX) LDTP04129 0.99  LDD0287 
Eukaryotic translation initiation factor 1b (EIF1B) LDTP16815 1.03  LDD0287 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 1.21  LDD0287 
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) LDTP03027 1.52  LDD0287 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 1.58  LDD0287 
Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 1.04  LDD0287 
Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 0.92  LDD0287 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 0.86  LDD0287 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 1.08; 1.08  LDD0287 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 0.99  LDD0287 
Eukaryotic translation initiation factor 4H (EIF4H) LDTP06301 0.36  LDD0287 
F-actin-uncapping protein LRRC16A (CARMIL1) LDTP07261 1.43  LDD0287 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 1.58; 1.46; 1.65  LDD0287 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 0.95; 1.20; 1.08 ...  LDD0287 
G antigen 2B/2C (GAGE2B; GAGE2C) LDTP17028 6.33  LDD0287 
Gelsolin (GSN) LDTP02145 1.03; 0.79; 1.05 ...  LDD0287 
General transcription factor IIF subunit 2 (GTF2F2) LDTP02703 0.94; 0.94  LDD0287 
Growth factor receptor-bound protein 2 (GRB2) LDTP05035 0.98  LDD0287 
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPVD1) LDTP06255 2.52; 1.65  LDD0287 
Heat shock 70 kDa protein 1A (HSPA1A) LDTP02434 0.90; 0.84; 0.79 ...  LDD0287 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 0.79; 0.91; 0.78 ...  LDD0287 
Heat shock 70 kDa protein 4L (HSPA4L) LDTP14545 4.05  LDD0287 
Heat shock protein 105 kDa (HSPH1) LDTP09811 1.68; 0.80  LDD0287 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 1.32  LDD0287 
Heat shock protein beta-1 (HSPB1) LDTP02053 1.08; 1.06; 0.87 ...  LDD0287 
Heme-binding protein 1 (HEBP1) LDTP16078 1.16; 0.82  LDD0287 
Hepatoma-derived growth factor (HDGF) LDTP04483 1.06  LDD0287 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 1.00; 1.16  LDD0287 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 1.02; 1.10; 1.14 ...  LDD0287 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 1.20; 1.14; 1.17  LDD0287 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 0.99  LDD0287 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 1.03; 0.94; 3.38 ...  LDD0287 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 0.65; 1.05; 0.97 ...  LDD0287 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 0.85; 1.53; 1.03 ...  LDD0287 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 0.89  LDD0287 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 1.09  LDD0287 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 1.23; 1.52; 1.39 ...  LDD0287 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 0.98; 1.08; 1.91 ...  LDD0287 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 1.22  LDD0287 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 0.97; 1.13; 1.50 ...  LDD0287 
Histone H2B type 1-D (H2BC5) LDTP04822 0.39; 0.42; 0.85 ...  LDD0287 
Histone H2B type 1-L (H2BC13) LDTP11001 2.41  LDD0287 
Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) LDTP05004 1.86; 0.67  LDD0287 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 1.00; 0.80  LDD0287 
Hsc70-interacting protein (ST13) LDTP04367 0.75; 0.88  LDD0287 
Influenza virus NS1A-binding protein (IVNS1ABP) LDTP14309 1.37  LDD0287 
Integrator complex subunit 10 (INTS10) LDTP16111 1.35  LDD0287 
IST1 homolog (IST1) LDTP04593 0.93  LDD0287 
Kinesin light chain 1 (KLC1) LDTP05533 2.28; 0.80  LDD0287 
Kinesin light chain 2 (KLC2) LDTP11695 2.28; 0.80  LDD0287 
Laminin subunit beta-2 (LAMB2) LDTP04691 1.36  LDD0287 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 1.00  LDD0287 
Large ribosomal subunit protein eL21 (RPL21) LDTP04107 1.03; 0.53; 0.93  LDD0287 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 1.38; 1.04  LDD0287 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 0.24; 5.83  LDD0287 
Large ribosomal subunit protein eL29 (RPL29) LDTP04140 1.04  LDD0287 
Large ribosomal subunit protein eL31 (RPL31) LDTP05023 1.86  LDD0287 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 6.33; 0.98  LDD0287 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 1.06  LDD0287 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 1.24  LDD0287 
Large ribosomal subunit protein eL37 (RPL37) LDTP04943 1.20  LDD0287 
Large ribosomal subunit protein eL43 (RPL37A) LDTP04926 1.06  LDD0287 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 0.90  LDD0287 
Large ribosomal subunit protein uL13 (RPL13A) LDTP03899 1.08; 1.04; 1.12  LDD0287 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 1.06  LDD0287 
Large ribosomal subunit protein uL15 (RPL27A) LDTP04105 1.32  LDD0287 
Large ribosomal subunit protein uL18 (RPL5) LDTP04106 0.70  LDD0287 
Large ribosomal subunit protein uL2 (RPL8) LDTP05027 1.08  LDD0287 
Large ribosomal subunit protein uL22 (RPL17) LDTP02961 1.06  LDD0287 
Large ribosomal subunit protein uL29 (RPL35) LDTP03999 1.72  LDD0287 
Large ribosomal subunit protein uL30 (RPL7) LDTP02944 0.53  LDD0287 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 0.41; 1.00; 0.84 ...  LDD0287 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 1.07; 1.12  LDD0287 
LIM domain and actin-binding protein 1 (LIMA1) LDTP13260 2.05; 1.08  LDD0287 
LRP chaperone MESD (MESD) LDTP06191 0.79  LDD0287 
Macrophage-capping protein (CAPG) LDTP03877 10.39; 0.74  LDD0287 
Microtubule-associated protein 4 (MAP4) LDTP03404 1.23; 0.05  LDD0287 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 0.49  LDD0287 
Muscleblind-like protein 1 (MBNL1) LDTP12478 1.31; 1.43  LDD0287 
Muscleblind-like protein 2 (MBNL2) LDTP07260 1.31  LDD0287 
Muscleblind-like protein 3 (MBNL3) LDTP12630 1.43  LDD0287 
Myeloid-derived growth factor (MYDGF) LDTP10003 1.92  LDD0287 
Myosin light polypeptide 6 (MYL6) LDTP04875 0.71  LDD0287 
Myosin regulatory light chain 12B (MYL12B) LDTP00487 1.00  LDD0287 
Myotrophin (MTPN) LDTP04819 1.17  LDD0287 
N6-adenosine-methyltransferase non-catalytic subunit (METTL14) LDTP12234 1.37  LDD0287 
Nascent polypeptide-associated complex subunit alpha (NACA) LDTP05977 0.09; 0.85  LDD0287 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 0.93; 0.99  LDD0287 
Nuclear migration protein nudC (NUDC) LDTP13817 1.07  LDD0287 
Nucleolin (NCL) LDTP02990 1.63; 1.27; 1.01 ...  LDD0287 
Nucleolysin TIAR (TIAL1) LDTP05274 1.20  LDD0287 
Nucleophosmin (NPM1) LDTP02164 0.95; 1.15; 0.73  LDD0287 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 0.35; 1.58; 1.26  LDD0287 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 0.98; 1.26  LDD0287 
Oxysterol-binding protein-related protein 11 (OSBPL11) LDTP11367 2.22  LDD0287 
Perilipin-3 (PLIN3) LDTP01021 1.00  LDD0287 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 0.71; 2.29; 1.00 ...  LDD0287 
Plastin-3 (PLS3) LDTP02692 0.82; 0.97  LDD0287 
Platelet-activating factor acetylhydrolase IB subunit beta (PAFAH1B1) LDTP04015 1.03; 0.92  LDD0287 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 1.05; 1.45; 1.07  LDD0287 
Poly(rC)-binding protein 2 (PCBP2) LDTP06367 0.69; 0.73; 0.93  LDD0287 
Polyadenylate-binding protein 1 (PABPC1) LDTP02595 1.56; 1.09; 0.95 ...  LDD0287 
Polyadenylate-binding protein 4 (PABPC4) LDTP05821 0.86; 0.81  LDD0287 
Polypyrimidine tract-binding protein 1 (PTBP1) LDTP03364 0.95; 0.98  LDD0287 
Prefoldin subunit 3 (VBP1) LDTP04935 1.33  LDD0287 
Prefoldin subunit 6 (PFDN6) LDTP00573 1.20  LDD0287 
Prelamin-A/C (LMNA) LDTP01932 1.25; 0.93  LDD0287 
Profilin-1 (PFN1) LDTP02218 0.96; 0.96  LDD0287 
Programmed cell death protein 5 (PDCD5) LDTP00417 1.08; 1.89  LDD0287 
Proliferating cell nuclear antigen (PCNA) LDTP02596 0.53; 0.81  LDD0287 
Protein FAM118B (FAM118B) LDTP15852 0.91  LDD0287 
Protein flightless-1 homolog (FLII) LDTP05734 1.06  LDD0287 
Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) LDTP13656 0.64; 0.98; 1.28 ...  LDD0287 
Protein LSM12 (LSM12) LDTP06780 1.07  LDD0287 
Protein mago nashi homolog 2 (MAGOHB) LDTP10071 0.77  LDD0287 
Protein NipSnap homolog 3A (NIPSNAP3A) LDTP18525 1.42; 1.43  LDD0287 
Protein RCC2 (RCC2) LDTP13020 0.98  LDD0287 
Protein S100-A11 (S100A11) LDTP03620 1.16; 1.12  LDD0287 
Protein SET (SET) LDTP05277 1.00  LDD0287 
Protein SGT1 homolog (SUGT1) LDTP13935 0.36; 1.47  LDD0287 
Protein TFG (TFG) LDTP09851 1.47  LDD0287 
Protein transport protein Sec23A (SEC23A) LDTP06390 0.37; 1.08  LDD0287 
Protein transport protein Sec23B (SEC23B) LDTP06391 0.71  LDD0287 
Protein UXT (UXT) LDTP13125 0.80  LDD0287 
Protein VAC14 homolog (VAC14) LDTP05586 0.19  LDD0287 
Putative protein FAM10A5 (ST13P5) LDTP17811 0.88  LDD0287 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 0.93  LDD0287 
Pyridoxal phosphate homeostasis protein (PLPBP) LDTP14521 0.13; 0.64  LDD0287 
Rab GDP dissociation inhibitor alpha (GDI1) LDTP03574 0.74; 1.06  LDD0287 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 0.82; 0.87; 0.22 ...  LDD0287 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 1.57  LDD0287 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 0.85; 1.02; 0.05 ...  LDD0287 
Reticulocalbin-1 (RCN1) LDTP06352 1.25  LDD0287 
Retinoblastoma-associated protein (RB1) LDTP02146 0.64  LDD0287 
Rho GDP-dissociation inhibitor 1 (ARHGDIA) LDTP04510 0.89; 0.92; 1.09 ...  LDD0287 
Rho guanine nucleotide exchange factor 2 (ARHGEF2) LDTP09950 0.78  LDD0287 
Ribosome biogenesis protein WDR12 (WDR12) LDTP11625 0.97  LDD0287 
RNA-binding protein 3 (RBM3) LDTP05226 1.11; 1.19  LDD0287 
RNA-binding protein EWS (EWSR1) LDTP05318 1.36  LDD0287 
RNA-binding protein FUS (FUS) LDTP03775 1.38; 1.18  LDD0287 
Serine/arginine-rich splicing factor 2 (SRSF2) LDTP05280 1.21  LDD0287 
Serine/arginine-rich splicing factor 8 (SRSF8) LDTP11117 1.21  LDD0287 
Serpin H1 (SERPINH1) LDTP04363 0.98  LDD0287 
Single-stranded DNA-binding protein, mitochondrial (SSBP1) LDTP05437 0.64; 1.21; 1.11 ...  LDD0287 
Small acidic protein (SMAP) LDTP19007 1.26  LDD0287 
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) LDTP00862 0.91; 0.38; 0.85 ...  LDD0287 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 1.04; 0.78; 0.74  LDD0287 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 0.73; 2.22  LDD0287 
Small ribosomal subunit protein eS19 (RPS19) LDTP03864 1.71  LDD0287 
Small ribosomal subunit protein eS24 (RPS24) LDTP05012 0.84; 1.96; 0.95  LDD0287 
Small ribosomal subunit protein eS26 (RPS26) LDTP05014 0.98  LDD0287 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 1.13; 1.04  LDD0287 
Small ribosomal subunit protein eS4, Y isoform 1 (RPS4Y1) LDTP14653 1.04  LDD0287 
Small ribosomal subunit protein eS4, Y isoform 2 (RPS4Y2) LDTP19820 1.04  LDD0287 
Small ribosomal subunit protein eS7 (RPS7) LDTP04958 0.91  LDD0287 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 1.06; 1.77; 1.36 ...  LDD0287 
Small ribosomal subunit protein uS11 (RPS14) LDTP04970 1.05  LDD0287 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 0.65  LDD0287 
Small ribosomal subunit protein uS13 (RPS18) LDTP04972 2.20; 2.43; 1.63  LDD0287 
Small ribosomal subunit protein uS15 (RPS13) LDTP04974 1.06; 1.39; 0.97  LDD0287 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 1.13; 1.03  LDD0287 
Small ribosomal subunit protein uS2 (RPSA) LDTP02312 0.80  LDD0287 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 1.13; 1.29; 1.00  LDD0287 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 1.11; 1.31  LDD0287 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 1.25; 0.70  LDD0287 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 1.38  LDD0287 
Src substrate cortactin (CTTN) LDTP06094 1.05; 0.83; 0.99 ...  LDD0287 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 1.14; 0.59; 0.34 ...  LDD0287 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 0.65; 0.27; 0.96 ...  LDD0287 
Stromal cell-derived factor 2-like protein 1 (SDF2L1) LDTP16047 1.36  LDD0287 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 1.12; 1.16  LDD0287 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 1.19  LDD0287 
Structural maintenance of chromosomes protein 4 (SMC4) LDTP12606 1.06  LDD0287 
T-complex protein 1 subunit beta (CCT2) LDTP05113 0.90; 2.87  LDD0287 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 1.13; 0.81  LDD0287 
T-complex protein 1 subunit eta (CCT7) LDTP10990 0.38  LDD0287 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 1.07; 0.85  LDD0287 
T-complex protein 1 subunit theta (CCT8) LDTP04390 1.09; 0.39; 0.86 ...  LDD0287 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 0.98  LDD0287 
T-complex protein 1 subunit zeta-2 (CCT6B) LDTP09777 0.98  LDD0287 
Tetratricopeptide repeat protein 1 (TTC1) LDTP15840 1.18  LDD0287 
Tetratricopeptide repeat protein 4 (TTC4) LDTP01678 1.10  LDD0287 
Transcription elongation factor A protein 1 (TCEA1) LDTP03209 1.20  LDD0287 
Transcription elongation factor SPT6 (SUPT6H) LDTP07928 0.99  LDD0287 
Transgelin-2 (TAGLN2) LDTP03846 1.10; 0.90; 1.03  LDD0287 
Translation initiation factor eIF2B subunit gamma (EIF2B3) LDTP12476 0.36  LDD0287 
Translationally-controlled tumor protein (TPT1) LDTP02683 0.92; 1.09  LDD0287 
Transmembrane glycoprotein NMB (GPNMB) LDTP06237 1.12  LDD0287 
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WDR6) LDTP12296 1.45  LDD0287 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 1.04  LDD0287 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 1.09  LDD0287 
Tubulin beta chain (TUBB) LDTP02205 1.35; 0.95; 1.22 ...  LDD0287 
Tubulin beta-2A chain (TUBB2A) LDTP05998 0.14; 1.49; 1.11 ...  LDD0287 
Tubulin beta-2B chain (TUBB2B) LDTP11277 0.67; 1.49; 1.11 ...  LDD0287 
Tubulin beta-3 chain (TUBB3) LDTP05904 1.06; 0.97; 1.54 ...  LDD0287 
Tubulin beta-4A chain (TUBB4A) LDTP02037 1.05; 1.07; 1.87 ...  LDD0287 
Tubulin beta-4B chain (TUBB4B) LDTP05076 0.80; 1.14; 1.06 ...  LDD0287 
Tubulin beta-6 chain (TUBB6) LDTP11233 1.08; 1.27; 0.34 ...  LDD0287 
Tubulin gamma-1 chain (TUBG1) LDTP03213 1.43  LDD0287 
Tubulin gamma-2 chain (TUBG2) LDTP12512 1.43  LDD0287 
Tubulin-folding cofactor B (TBCB) LDTP10860 1.24; 1.06  LDD0287 
U6 snRNA-associated Sm-like protein LSm2 (LSM2) LDTP13946 1.16  LDD0287 
Ubiquilin-1 (UBQLN1) LDTP13626 1.08  LDD0287 
Ubiquitin-associated protein 2-like (UBAP2L) LDTP06060 3.45; 1.47  LDD0287 
Ubiquitin-fold modifier 1 (UFM1) LDTP04946 1.05  LDD0287 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 1.26  LDD0287 
Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) LDTP11534 1.48  LDD0287 
Vacuolar fusion protein CCZ1 homolog (CCZ1) LDTP14797 1.34  LDD0287 
Vasodilator-stimulated phosphoprotein (VASP) LDTP04372 1.05  LDD0287 
Vimentin (VIM) LDTP02297 0.97; 0.87; 0.59 ...  LDD0287 
Vinculin (VCL) LDTP02946 2.43; 1.00  LDD0287 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 1.27  LDD0287 
WD repeat-containing protein 1 (WDR1) LDTP01118 1.04; 1.33; 0.87 ...  LDD0287 
WW domain-binding protein 2 (WBP2) LDTP10033 1.75; 2.89; 1.32  LDD0287 
Zyxin (ZYX) LDTP06507 1.29; 0.92  LDD0287 
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Full Information of The Labelling Profiles of This Competitor

HHS-482
 Probe Info 
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 50 uM
Quantitative Method SILAC
Competitor Name JWB146
Competitor Concentration 50 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Skin
Disease Model Melanoma [ICD-11:2C82]
Model Name Human melanoma cell lysate (DM93)
Interaction Atlas ID  LDD0287  Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 50 uM
Quantitative Method SILAC
Competitor Name JWB146
Competitor Concentration 50 uM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Skin
Disease Model Melanoma [ICD-11:2C82]
Model Name Human melanoma cells (DM93)
Interaction Atlas ID  LDD0293  Download The Altas

References

1 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.