Details of the Target
General Information of Target
| Target ID | LDTP17028 | |||||
|---|---|---|---|---|---|---|
| Target Name | G antigen 2B/2C (GAGE2B; GAGE2C) | |||||
| Gene Name | GAGE2B; GAGE2C | |||||
| Gene ID | 2574 | |||||
| Synonyms |
GAGE2; G antigen 2B/2C; GAGE-2B; GAGE-2C; Cancer/testis antigen 4.2; CT4.2; G antigen 2C |
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| 3D Structure | ||||||
| Sequence |
MGPLSAPPCTQHITWKGLLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ
NLTGYIWYKGQIRDLYHYVTSYIVDGQIIKYGPAYSGRETVYSNASLLIQNVTQEDTGSY TLHIIKRGDGTGGVTGRFTFTLYLETPKPSISSSNFNPREATEAVILTCDPETPDASYLW WMNGQSLPMTHSLQLSETNRTLYLFGVTNYTAGPYECEIRNPVSASRSDPVTLNLLPKLP KPYITINNLNPRENKDVSTFTCEPKSENYTYIWWLNGQSLPVSPRVKRRIENRILILPSV TRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYHSGQNLYLSCFADSNP PAQYSWTINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSVTVRVSDWTLP |
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| Target Bioclass |
Other
|
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| Family |
GAGE family
|
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| Function | Antigen, recognized on melanoma by autologous cytolytic T-lymphocytes. | |||||
| Uniprot ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
HHS-482 Probe Info |
 |
Y16(6.33) | LDD0287 | [1] | |
|
HHS-475 Probe Info |
 |
Y16(1.07) | LDD0264 | [2] | |
Competitor(s) Related to This Target
| Competitor ID | Name | Cell line | Binding Site(Ratio) | Interaction ID | Ref |
|---|---|---|---|---|---|
| LDCM0116 | HHS-0101 | DM93 | Y16(1.07) | LDD0264 | [2] |
| LDCM0117 | HHS-0201 | DM93 | Y16(1.21) | LDD0265 | [2] |
| LDCM0118 | HHS-0301 | DM93 | Y16(1.27) | LDD0266 | [2] |
| LDCM0119 | HHS-0401 | DM93 | Y16(1.59) | LDD0267 | [2] |
| LDCM0120 | HHS-0701 | DM93 | Y16(2.05) | LDD0268 | [2] |
| LDCM0125 | JWB146 | DM93 | Y16(6.33) | LDD0287 | [1] |
| LDCM0126 | JWB150 | DM93 | Y16(16.63) | LDD0288 | [1] |
The Interaction Atlas With This Target
References