General Information of Competitor

Competitor ID
LDCM0126
Competitor Name
JWB150
Synonyms
SCHEMBL22558345; ASVKVIILQGWQKV-UHFFFAOYSA-N; 1-(4-Fluorophenyl)sulfonyl-3-[4-(trifluoromethyl)phenyl]-1,2,4-triazole
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 371.3
Lipid-water partition coefficient (xlogp) 3.9
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C15H9F4N3O2S
IUPAC Name
1-(4-fluorophenyl)sulfonyl-3-[4-(trifluoromethyl)phenyl]-1,2,4-triazole
Canonical SMILES
C1=CC(=CC=C1C2=NN(C=N2)S(=O)(=O)C3=CC=C(C=C3)F)C(F)(F)F
InChI
InChI=1S/C15H9F4N3O2S/c16-12-5-7-13(8-6-12)25(23,24)22-9-20-14(21-22)10-1-3-11(4-2-10)15(17,18)19/h1-9H
InChIKey
ASVKVIILQGWQKV-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
HHS-482
 Probe Info 
50 uM Human melanoma cell lysate (DM93) [1]

Target(s) List of this Competitor

305 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
(3R)-3-hydroxyacyl-CoA dehydrogenase (HSD17B8) LDTP09770 2.24  LDD0288 
1,4-alpha-glucan-branching enzyme (GBE1) LDTP05419 20.00  LDD0288 
14 kDa phosphohistidine phosphatase (PHPT1) LDTP12543 4.79; 4.52  LDD0288 
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) LDTP02356 4.54  LDD0288 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 2.00; 20.00  LDD0288 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 3.84  LDD0288 
26S proteasome non-ATPase regulatory subunit 3 (PSMD3) LDTP00714 4.92  LDD0288 
26S proteasome non-ATPase regulatory subunit 5 (PSMD5) LDTP06532 5.43  LDD0288 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 6.65  LDD0288 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 2.76  LDD0288 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 20.00; 20.00  LDD0288 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 1.98  LDD0288 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 5.90  LDD0288 
5'-3' exoribonuclease 2 (XRN2) LDTP11701 2.49  LDD0288 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 3.32; 5.40; 2.46 ...  LDD0288 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 1.78  LDD0288 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 2.79  LDD0288 
Acetyl-CoA carboxylase 1 (ACACA) LDTP05742 0.53  LDD0288 
Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) LDTP12463 0.79  LDD0288 
Actin, alpha cardiac muscle 1 (ACTC1) LDTP05069 2.84  LDD0288 
Actin, cytoplasmic 1 (ACTB) LDTP04876 2.40; 3.23; 6.16 ...  LDD0288 
Acylamino-acid-releasing enzyme (APEH) LDTP02693 1.71  LDD0288 
Adenosylhomocysteinase (AHCY) LDTP03242 2.47; 2.20  LDD0288 
Adenylosuccinate synthetase isozyme 2 (ADSS2) LDTP03541 5.02  LDD0288 
ADP-ribose pyrophosphatase, mitochondrial (NUDT9) LDTP11318 2.67  LDD0288 
ADP-ribosylation factor 1 (ARF1) LDTP05192 3.18; 3.37; 3.46  LDD0288 
ADP-ribosylation factor 3 (ARF3) LDTP04907 3.18; 3.37; 3.46  LDD0288 
ADP-ribosylation factor 4 (ARF4) LDTP02942 3.18; 3.37  LDD0288 
ADP-ribosylation factor 5 (ARF5) LDTP05193 3.18; 3.37  LDD0288 
ADP-sugar pyrophosphatase (NUDT5) LDTP13462 4.66  LDD0288 
Aflatoxin B1 aldehyde reductase member 2 (AKR7A2) LDTP00776 2.36; 1.71; 3.20 ...  LDD0288 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 1.72; 0.78  LDD0288 
Alcohol dehydrogenase class-3 (ADH5) LDTP02587 11.39; 1.67; 1.79  LDD0288 
Aldo-keto reductase family 1 member A1 (AKR1A1) LDTP02729 1.72  LDD0288 
Alpha-aminoadipic semialdehyde synthase, mitochondrial (AASS) LDTP13186 2.05; 0.69; 5.26  LDD0288 
Alpha-enolase (ENO1) LDTP02159 3.00; 3.80; 7.95 ...  LDD0288 
Amidophosphoribosyltransferase (PPAT) LDTP05480 2.03  LDD0288 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 0.28; 1.57  LDD0288 
Asparagine synthetase [glutamine-hydrolyzing] (ASNS) LDTP02264 11.43; 2.17  LDD0288 
Asparagine--tRNA ligase, cytoplasmic (NARS1) LDTP00866 2.91; 2.63; 5.13 ...  LDD0288 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 2.61; 3.65  LDD0288 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 8.95; 4.08; 3.90  LDD0288 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 3.00; 4.36  LDD0288 
ATP-citrate synthase (ACLY) LDTP04561 3.35; 2.14; 4.59 ...  LDD0288 
ATP-dependent 6-phosphofructokinase, liver type (PFKL) LDTP02925 2.77  LDD0288 
ATP-dependent 6-phosphofructokinase, muscle type (PFKM) LDTP02261 1.41  LDD0288 
ATP-dependent RNA helicase A (DHX9) LDTP05550 1.53; 3.49  LDD0288 
ATP-dependent RNA helicase DDX1 (DDX1) LDTP09766 5.00; 10.10  LDD0288 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 5.65  LDD0288 
ATPase MORC2 (MORC2) LDTP14308 11.75  LDD0288 
Aurora kinase B (AURKB) LDTP10346 0.69  LDD0288 
Bifunctional coenzyme A synthase (COASY) LDTP05736 2.04  LDD0288 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 5.57; 4.39  LDD0288 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 4.00  LDD0288 
Biliverdin reductase A (BLVRA) LDTP04552 2.21  LDD0288 
Biotinidase (BTD) LDTP04030 7.28  LDD0288 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 7.72; 2.50; 2.84 ...  LDD0288 
Calcyclin-binding protein (CACYBP) LDTP12163 8.11; 4.26; 6.98  LDD0288 
Carbonyl reductase [NADPH] 1 (CBR1) LDTP02831 1.99  LDD0288 
Carbonyl reductase [NADPH] 3 (CBR3) LDTP01321 2.69  LDD0288 
Casein kinase II subunit beta (CSNK2B) LDTP05067 1.36  LDD0288 
Catalase (CAT) LDTP02001 1.50  LDD0288 
Cathepsin B (CTSB) LDTP02223 2.75; 2.61; 2.41 ...  LDD0288 
Cathepsin D (CTSD) LDTP02198 2.14; 3.17  LDD0288 
Cathepsin Z (CTSZ) LDTP13147 2.71; 3.92; 7.17 ...  LDD0288 
Citrate synthase, mitochondrial (CS) LDTP01205 1.19; 4.75; 2.70  LDD0288 
Cleavage and polyadenylation specificity factor subunit 5 (NUDT21) LDTP00873 1.58  LDD0288 
CTP synthase 1 (CTPS1) LDTP02922 6.27; 3.53; 2.75  LDD0288 
Cyclin-dependent kinase 1 (CDK1) LDTP02149 3.00; 4.10; 2.91 ...  LDD0288 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 3.00; 2.91; 16.45  LDD0288 
Cystathionine gamma-lyase (CTH) LDTP03656 2.87  LDD0288 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 1.59  LDD0288 
Cytochrome c oxidase assembly factor 7 (COA7) LDTP10137 2.74  LDD0288 
Cytoglobin (CYGB) LDTP09656 3.71; 3.80  LDD0288 
Cytosol aminopeptidase (LAP3) LDTP03455 5.53  LDD0288 
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 13.37; 2.92  LDD0288 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 3.77  LDD0288 
Dehydrogenase/reductase SDR family member 11 (DHRS11) LDTP07678 2.69  LDD0288 
Dihydropteridine reductase (QDPR) LDTP02342 1.01  LDD0288 
Dihydropyrimidinase-related protein 3 (DPYSL3) LDTP06079 3.41  LDD0288 
Dipeptidyl peptidase 3 (DPP3) LDTP12803 1.46  LDD0288 
DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 3.94  LDD0288 
DNA replication licensing factor MCM2 (MCM2) LDTP04286 2.28  LDD0288 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 4.88  LDD0288 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 3.48  LDD0288 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 0.16  LDD0288 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 1.82  LDD0288 
DNA replication licensing factor MCM7 (MCM7) LDTP03682 2.43  LDD0288 
Dual specificity protein phosphatase 23 (DUSP23) LDTP11289 2.05  LDD0288 
Dual specificity protein phosphatase 3 (DUSP3) LDTP04415 3.63  LDD0288 
Dynamin-1-like protein (DNM1L) LDTP00273 2.27  LDD0288 
E3 ubiquitin-protein ligase ARIH2 (ARIH2) LDTP01575 4.33  LDD0288 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 2.11  LDD0288 
E3 ubiquitin-protein ligase UBR4 (UBR4) LDTP07118 11.42  LDD0288 
EH domain-containing protein 4 (EHD4) LDTP11788 2.41  LDD0288 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 4.24; 2.94; 2.96 ...  LDD0288 
Elongation factor 2 (EEF2) LDTP02672 5.48; 1.22; 20.00 ...  LDD0288 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 3.89; 2.39; 3.64 ...  LDD0288 
Endoplasmic reticulum chaperone BiP (HSPA5) LDTP02534 20.00; 1.67; 1.80 ...  LDD0288 
Enoyl-CoA hydratase, mitochondrial (ECHS1) LDTP03518 2.42  LDD0288 
ERO1-like protein alpha (ERO1A) LDTP10386 3.09  LDD0288 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 1.98; 2.98; 7.54 ...  LDD0288 
Eukaryotic initiation factor 4A-III (EIF4A3) LDTP03861 3.11  LDD0288 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 3.83  LDD0288 
Exosome complex exonuclease RRP44 (DIS3) LDTP13887 2.13  LDD0288 
Farnesyl pyrophosphate synthase (FDPS) LDTP02721 6.18  LDD0288 
Fatty acid CoA ligase Acsl3 (ACSL3) LDTP01634 18.66; 5.57  LDD0288 
Fatty acid synthase (FASN) LDTP04243 4.35; 4.89; 3.52 ...  LDD0288 
Flap endonuclease 1 (FEN1) LDTP03872 4.50  LDD0288 
Fructose-2,6-bisphosphatase TIGAR (TIGAR) LDTP12405 1.89  LDD0288 
Fructose-bisphosphate aldolase A (ALDOA) LDTP02008 4.14; 4.24; 4.85 ...  LDD0288 
Fumarate hydratase, mitochondrial (FH) LDTP02235 2.04  LDD0288 
Fumarylacetoacetase (FAH) LDTP02868 1.25  LDD0288 
Galactokinase (GALK1) LDTP04424 1.76  LDD0288 
Gamma-enolase (ENO2) LDTP02328 2.61; 3.71  LDD0288 
GDP-mannose 4,6 dehydratase (GMDS) LDTP00999 2.63  LDD0288 
Geranylgeranyl transferase type-2 subunit beta (RABGGTB) LDTP04569 2.69  LDD0288 
Glucosamine-6-phosphate isomerase 1 (GNPDA1) LDTP04113 10.29  LDD0288 
Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 12.57; 3.55  LDD0288 
Glucose-6-phosphate isomerase (GPI) LDTP02162 0.43; 7.15  LDD0288 
Glutaminase kidney isoform, mitochondrial (GLS) LDTP01465 1.19  LDD0288 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) LDTP05481 2.18; 4.88  LDD0288 
Glutaredoxin-1 (GLRX) LDTP03786 3.28  LDD0288 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 2.72; 3.74  LDD0288 
Glutathione S-transferase A4 (GSTA4) LDTP00575 5.00  LDD0288 
Glutathione S-transferase kappa 1 (GSTK1) LDTP13900 1.71  LDD0288 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 2.09  LDD0288 
Glutathione S-transferase P (GSTP1) LDTP02333 5.15; 8.48; 4.17 ...  LDD0288 
Glutathione synthetase (GSS) LDTP04200 2.89  LDD0288 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 7.94; 2.97; 3.45 ...  LDD0288 
Glycine--tRNA ligase (GARS1) LDTP03946 3.64; 3.47; 20.00 ...  LDD0288 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 2.85; 2.96; 3.11 ...  LDD0288 
Glycogen phosphorylase, liver form (PYGL) LDTP02161 2.86  LDD0288 
Glycogen synthase kinase-3 alpha (GSK3A) LDTP04318 10.78  LDD0288 
Glycogen synthase kinase-3 beta (GSK3B) LDTP04319 10.78  LDD0288 
GTP-binding nuclear protein Ran (RAN) LDTP05007 5.28; 2.40; 2.35 ...  LDD0288 
HBS1-like protein (HBS1L) LDTP14019 1.86  LDD0288 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 3.94; 4.18; 2.94 ...  LDD0288 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 0.70; 2.04; 4.84 ...  LDD0288 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 5.02  LDD0288 
Histone deacetylase 1 (HDAC1) LDTP05918 3.09  LDD0288 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 1.35  LDD0288 
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL) LDTP03794 2.33  LDD0288 
Inorganic pyrophosphatase (PPA1) LDTP14854 1.65; 4.73; 5.00 ...  LDD0288 
Inorganic pyrophosphatase 2, mitochondrial (PPA2) LDTP11842 7.06  LDD0288 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 2.47; 3.84; 2.77 ...  LDD0288 
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) LDTP11700 6.11  LDD0288 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 2.11; 2.37; 4.21  LDD0288 
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A) LDTP04345 0.20  LDD0288 
Isoleucine--tRNA ligase, cytoplasmic (IARS1) LDTP03947 2.24  LDD0288 
Kynurenine--oxoglutarate transaminase 3 (KYAT3) LDTP07763 0.74; 2.12  LDD0288 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 3.08; 3.49; 4.26 ...  LDD0288 
L-lactate dehydrogenase B chain (LDHB) LDTP02179 3.60; 2.47; 5.15 ...  LDD0288 
L-xylulose reductase (DCXR) LDTP08082 3.78  LDD0288 
Lactoylglutathione lyase (GLO1) LDTP05434 4.67  LDD0288 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 7.45  LDD0288 
Low molecular weight phosphotyrosine protein phosphatase (ACP1) LDTP03289 5.62; 5.52; 4.96  LDD0288 
Lymphokine-activated killer T-cell-originated protein kinase (PBK) LDTP10500 3.12; 6.83; 2.82  LDD0288 
Lysosomal protective protein (CTSA) LDTP02505 13.28  LDD0288 
Macrophage migration inhibitory factor (MIF) LDTP02713 2.93; 5.21; 4.38 ...  LDD0288 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 3.44; 3.81  LDD0288 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 1.70; 1.23; 2.07 ...  LDD0288 
Mannose-1-phosphate guanyltransferase beta (GMPPB) LDTP14141 2.10  LDD0288 
MAP kinase-activated protein kinase 3 (MAPKAPK3) LDTP06589 20.00; 2.82  LDD0288 
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) LDTP02565 1.85; 2.70; 0.13 ...  LDD0288 
Methionine adenosyltransferase 2 subunit beta (MAT2B) LDTP12915 1.93  LDD0288 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 2.55  LDD0288 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 2.60  LDD0288 
Methylthioribulose-1-phosphate dehydratase (APIP) LDTP10368 1.91  LDD0288 
Mitochondrial-processing peptidase subunit beta (PMPCB) LDTP01220 7.72  LDD0288 
Mitogen-activated protein kinase 1 (MAPK1) LDTP03445 4.05; 3.61  LDD0288 
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) LDTP01005 3.49; 3.01  LDD0288 
Myosin-10 (MYH10) LDTP03765 1.40; 5.47; 3.57 ...  LDD0288 
Myosin-9 (MYH9) LDTP03764 4.27; 5.83; 1.48 ...  LDD0288 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 2.02  LDD0288 
NAD(P)H dehydrogenase [quinone] 1 (NQO1) LDTP02798 3.64; 16.47; 6.44 ...  LDD0288 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 1.82  LDD0288 
NEDD8-conjugating enzyme Ubc12 (UBE2M) LDTP04898 4.33  LDD0288 
Neutral alpha-glucosidase AB (GANAB) LDTP06192 3.99  LDD0288 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 10.70  LDD0288 
Nucleoside diphosphate kinase B (NME2) LDTP03169 2.19  LDD0288 
Omega-amidase NIT2 (NIT2) LDTP12428 6.39; 3.74; 4.62 ...  LDD0288 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 1.57; 2.18; 2.46  LDD0288 
Palmitoyltransferase ZDHHC17 (ZDHHC17) LDTP08456 0.05  LDD0288 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 5.34; 3.54  LDD0288 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 10.89  LDD0288 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 3.56; 4.15  LDD0288 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 2.37; 11.36; 3.22  LDD0288 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) LDTP05912 3.35  LDD0288 
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3) LDTP11823 2.63  LDD0288 
Peroxiredoxin-1 (PRDX1) LDTP05503 5.06; 4.45  LDD0288 
Peroxiredoxin-4 (PRDX4) LDTP05773 5.43; 4.31  LDD0288 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 1.74  LDD0288 
Phosphatidylinositide phosphatase SAC2 (INPP5F) LDTP13867 2.12  LDD0288 
Phosphoglucomutase-1 (PGM1) LDTP03818 18.86  LDD0288 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 6.02; 2.25; 3.67 ...  LDD0288 
Phosphoglycerate mutase 1 (PGAM1) LDTP02963 3.70; 1.43; 4.76 ...  LDD0288 
Phosphoserine aminotransferase (PSAT1) LDTP14198 3.71; 2.57; 3.68 ...  LDD0288 
Poly(A) polymerase alpha (PAPOLA) LDTP04394 1.96  LDD0288 
Probable 18S rRNA (guanine-N(7))-methyltransferase (BUD23) LDTP00845 2.86  LDD0288 
Probable aminopeptidase NPEPL1 (NPEPL1) LDTP09126 3.28  LDD0288 
Probable E3 ubiquitin-protein ligase IRF2BPL (IRF2BPL) LDTP11759 2.65; 1.50  LDD0288 
Prolyl endopeptidase (PREP) LDTP04163 2.43  LDD0288 
Prostaglandin reductase 1 (PTGR1) LDTP06227 1.94  LDD0288 
Prostaglandin reductase 2 (PTGR2) LDTP08979 1.76; 1.88; 2.49  LDD0288 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 2.13; 4.11  LDD0288 
Proteasome subunit alpha type-2 (PSMA2) LDTP03331 2.13; 2.74; 3.02  LDD0288 
Proteasome subunit alpha type-3 (PSMA3) LDTP03332 2.67  LDD0288 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 2.75; 2.27; 4.04 ...  LDD0288 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 2.26; 2.67; 3.81 ...  LDD0288 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 1.79; 1.75  LDD0288 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 3.14; 0.31  LDD0288 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 2.34  LDD0288 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 1.92; 2.50  LDD0288 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 2.66; 3.64  LDD0288 
Protein arginine N-methyltransferase 5 (PRMT5) LDTP00418 0.96  LDD0288 
Protein disulfide-isomerase (P4HB) LDTP02188 11.53; 1.75; 4.42 ...  LDD0288 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 3.76; 4.76; 5.99 ...  LDD0288 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 8.11; 4.45; 15.16  LDD0288 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 3.43  LDD0288 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 1.81  LDD0288 
Protein kinase C delta type (PRKCD) LDTP05461 8.12  LDD0288 
Protein phosphatase 1G (PPM1G) LDTP00616 20.00  LDD0288 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 3.04  LDD0288 
Putative elongation factor 1-alpha-like 3 (EEF1A1P5) LDTP15029 4.24; 2.94; 2.99 ...  LDD0288 
Pyridoxine-5'-phosphate oxidase (PNPO) LDTP12691 2.58  LDD0288 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 1.51; 4.55  LDD0288 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 3.25; 3.29; 3.32 ...  LDD0288 
Pyruvate kinase PKM (PKM) LDTP02733 2.42; 2.91; 4.24 ...  LDD0288 
Queuine tRNA-ribosyltransferase catalytic subunit 1 (QTRT1) LDTP11400 1.82  LDD0288 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 1.24; 4.76  LDD0288 
RAC-gamma serine/threonine-protein kinase (AKT3) LDTP13799 2.99; 4.76  LDD0288 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 4.02; 4.85  LDD0288 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 3.07  LDD0288 
RING finger and CHY zinc finger domain-containing protein 1 (RCHY1) LDTP10686 2.52  LDD0288 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 1.30  LDD0288 
RNA demethylase ALKBH5 (ALKBH5) LDTP07547 2.10  LDD0288 
RNA-splicing ligase RtcB homolog (RTCB) LDTP13992 5.06  LDD0288 
RuvB-like 1 (RUVBL1) LDTP13816 2.48  LDD0288 
S-adenosylmethionine synthase isoform type-2 (MAT2A) LDTP03577 1.91; 2.52  LDD0288 
S-formylglutathione hydrolase (ESD) LDTP02521 5.34; 5.03  LDD0288 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 2.31  LDD0288 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 3.20  LDD0288 
Sepiapterin reductase (SPR) LDTP03730 1.87  LDD0288 
Septin-2 (SEPTIN2) LDTP06279 0.75; 1.29  LDD0288 
Septin-7 (SEPTIN7) LDTP06513 0.98; 2.80  LDD0288 
Septin-9 (SEPTIN9) LDTP13272 5.19; 4.19; 3.05  LDD0288 
Serine hydroxymethyltransferase, cytosolic (SHMT1) LDTP03688 2.24  LDD0288 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 0.55  LDD0288 
Serine/threonine-protein kinase PAK 2 (PAK2) LDTP05776 3.14  LDD0288 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 4.04  LDD0288 
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) LDTP05064 1.69; 5.24  LDD0288 
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB) LDTP04998 1.73  LDD0288 
Serine/threonine-protein phosphatase 4 catalytic subunit (PPP4C) LDTP04870 1.69  LDD0288 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 2.80  LDD0288 
Serine/threonine-protein phosphatase 6 catalytic subunit (PPP6C) LDTP00333 3.83  LDD0288 
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) LDTP04959 3.34; 3.33  LDD0288 
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) LDTP04960 3.34; 3.33  LDD0288 
Sialic acid synthase (NANS) LDTP12473 3.74; 2.85; 2.30  LDD0288 
Spermidine synthase (SRM) LDTP03008 3.68  LDD0288 
Spliceosome RNA helicase DDX39B (DDX39B) LDTP05991 2.35  LDD0288 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 2.76; 2.32  LDD0288 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 1.99  LDD0288 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 3.32  LDD0288 
SUMO-activating enzyme subunit 2 (UBA2) LDTP13156 3.12; 6.98  LDD0288 
SUMO-conjugating enzyme UBC9 (UBE2I) LDTP05062 20.00  LDD0288 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 3.02; 4.04; 3.08  LDD0288 
Thimet oligopeptidase (THOP1) LDTP04542 1.93  LDD0288 
Thioredoxin domain-containing protein 12 (TXNDC12) LDTP01707 3.99  LDD0288 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 3.46; 2.65; 3.14 ...  LDD0288 
Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) LDTP03515 4.32  LDD0288 
Threonine--tRNA ligase 1, cytoplasmic (TARS1) LDTP03365 0.79; 1.42; 1.96 ...  LDD0288 
Thymidylate kinase (DTYMK) LDTP03258 2.81  LDD0288 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 2.38; 3.70; 2.53 ...  LDD0288 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 3.00  LDD0288 
Transketolase (TKT) LDTP03487 12.78; 2.78; 2.75 ...  LDD0288 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 2.04  LDD0288 
Triosephosphate isomerase (TPI1) LDTP04851 1.04; 11.05; 1.26  LDD0288 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 6.65  LDD0288 
Tryptophan--tRNA ligase, cytoplasmic (WARS1) LDTP03222 3.78; 3.19; 5.52  LDD0288 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 2.30; 2.21; 2.31 ...  LDD0288 
Tubulin alpha-1B chain (TUBA1B) LDTP05074 2.30; 2.21; 2.31 ...  LDD0288 
Tubulin alpha-1C chain (TUBA1C) LDTP11074 3.08  LDD0288 
Tubulin--tyrosine ligase-like protein 12 (TTLL12) LDTP06067 0.46; 2.72  LDD0288 
Tyrosine--tRNA ligase, cytoplasmic (YARS1) LDTP04617 2.20; 4.29  LDD0288 
Tyrosine-protein kinase CSK (CSK) LDTP03944 3.39  LDD0288 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 6.42  LDD0288 
Ubiquitin carboxyl-terminal hydrolase 14 (USP14) LDTP04618 7.50  LDD0288 
Ubiquitin carboxyl-terminal hydrolase 39 (USP39) LDTP06903 2.87  LDD0288 
Ubiquitin carboxyl-terminal hydrolase 4 (USP4) LDTP05749 2.81  LDD0288 
Ubiquitin-conjugating enzyme E2 N (UBE2N) LDTP04900 8.58; 9.03; 4.05  LDD0288 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 5.77; 4.54; 2.87 ...  LDD0288 
UDP-glucose 4-epimerase (GALE) LDTP06111 16.81  LDD0288 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 2.18; 1.08; 3.20 ...  LDD0288 
UMP-CMP kinase (CMPK1) LDTP03519 1.28  LDD0288 
Unconventional myosin-Ie (MYO1E) LDTP05708 7.54  LDD0288 
Uridine 5'-monophosphate synthase (UMPS) LDTP02548 3.02  LDD0288 
Uridine phosphorylase 1 (UPP1) LDTP06643 3.54; 7.36; 3.88 ...  LDD0288 
Uroporphyrinogen decarboxylase (UROD) LDTP02135 1.10; 3.56  LDD0288 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 3.02; 5.27  LDD0288 
V-type proton ATPase subunit E 2 (ATP6V1E2) LDTP15684 2.22  LDD0288 
Valine--tRNA ligase (VARS1) LDTP03366 20.00; 5.77  LDD0288 
WD repeat-containing protein 82 (WDR82) LDTP07715 2.16  LDD0288 
Xaa-Pro aminopeptidase 1 (XPNPEP1) LDTP12444 6.23; 1.85  LDD0288 
Xaa-Pro dipeptidase (PEPD) LDTP02639 7.28  LDD0288 
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⏷ Show the Full List of 305 Enzyme
41 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein epsilon (YWHAE) LDTP04969 3.63; 3.64; 3.66 ...  LDD0288 
14-3-3 protein gamma (YWHAG) LDTP04953 0.33  LDD0288 
14-3-3 protein theta (YWHAQ) LDTP03385 5.74  LDD0288 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 3.04; 2.85; 3.19 ...  LDD0288 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 2.46; 2.30  LDD0288 
Alpha-crystallin B chain (CRYAB) LDTP01929 3.14  LDD0288 
Alpha-synuclein (SNCA) LDTP03848 5.51  LDD0288 
Annexin A2 (ANXA2) LDTP02199 2.38; 0.73; 4.52 ...  LDD0288 
Annexin A5 (ANXA5) LDTP02307 6.76; 6.73; 4.52 ...  LDD0288 
Annexin A6 (ANXA6) LDTP02247 3.83; 3.41  LDD0288 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 3.25  LDD0288 
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 4.40; 2.68  LDD0288 
Calreticulin (CALR) LDTP03402 3.01; 3.25; 6.24 ...  LDD0288 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 3.55; 2.04; 2.43 ...  LDD0288 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 4.02; 2.56; 2.25 ...  LDD0288 
Clathrin heavy chain 1 (CLTC) LDTP05252 1.12; 1.53  LDD0288 
Copine-3 (CPNE3) LDTP01133 2.73; 3.24  LDD0288 
Cystatin-B (CSTB) LDTP02009 3.92; 2.54; 2.73  LDD0288 
Dihydropyrimidinase-related protein 2 (DPYSL2) LDTP06554 1.36; 3.41; 4.32 ...  LDD0288 
Eukaryotic translation initiation factor 5A-1 (EIF5A) LDTP05056 7.18; 5.49  LDD0288 
Exportin-1 (XPO1) LDTP00501 4.34; 2.91  LDD0288 
Filamin-A (FLNA) LDTP03107 2.82; 3.68  LDD0288 
Galectin-3 (LGALS3) LDTP02929 2.66  LDD0288 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 3.24; 4.60; 4.10 ...  LDD0288 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 4.21  LDD0288 
Importin subunit beta-1 (KPNB1) LDTP06242 1.65  LDD0288 
mRNA export factor RAE1 (RAE1) LDTP05122 2.36  LDD0288 
Protein SEC13 homolog (SEC13) LDTP04707 5.85  LDD0288 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 2.89; 5.58  LDD0288 
Sorting nexin-2 (SNX2) LDTP01043 0.76  LDD0288 
T-complex protein 1 subunit delta (CCT4) LDTP04391 3.17; 2.53; 2.93 ...  LDD0288 
Talin-1 (TLN1) LDTP14031 1.95; 3.88; 0.91 ...  LDD0288 
Thioredoxin domain-containing protein 17 (TXNDC17) LDTP11103 2.71; 2.52; 5.38  LDD0288 
Transferrin receptor protein 1 (TFRC) LDTP01969 11.58  LDD0288 
Ubiquilin-4 (UBQLN4) LDTP12533 2.42  LDD0288 
V-type proton ATPase subunit B, brain isoform (ATP6V1B2) LDTP03104 5.94  LDD0288 
V-type proton ATPase subunit C 1 (ATP6V1C1) LDTP03105 5.06  LDD0288 
V-type proton ATPase subunit E 1 (ATP6V1E1) LDTP03811 2.22  LDD0288 
V-type proton ATPase subunit G 1 (ATP6V1G1) LDTP01185 1.70  LDD0288 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 4.27  LDD0288 
Voltage-gated potassium channel subunit beta-2 (KCNAB2) LDTP05817 3.43  LDD0288 
------------------------------------------------------------------------------------
⏷ Show the Full List of 41 Transporter and channel
9 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Forkhead box protein K1 (FOXK1) LDTP05201 9.88  LDD0288 
High mobility group protein B1 (HMGB1) LDTP02343 3.82; 10.00; 0.07 ...  LDD0288 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 4.64  LDD0288 
Nascent polypeptide-associated complex subunit alpha, muscle-specific form (NACA) LDTP14411 0.14  LDD0288 
Signal transducer and activator of transcription 3 (STAT3) LDTP03903 14.38  LDD0288 
Signal transducer and activator of transcription 5A (STAT5A) LDTP03971 5.05  LDD0288 
Transcription factor SOX-10 (SOX10) LDTP04752 4.59; 1.37  LDD0288 
Transcription factor SOX-9 (SOX9) LDTP04179 4.22  LDD0288 
Y-box-binding protein 1 (YBX1) LDTP05065 8.25; 4.74; 2.57  LDD0288 
------------------------------------------------------------------------------------
⏷ Show the Full List of 9 Transcription factor
281 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
10 kDa heat shock protein, mitochondrial (HSPE1) LDTP04931 8.33  LDD0288 
14-3-3 protein beta/alpha (YWHAB) LDTP03617 3.31; 3.50  LDD0288 
14-3-3 protein eta (YWHAH) LDTP05442 0.98  LDD0288 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 3.61  LDD0288 
55 kDa erythrocyte membrane protein (MPP1) LDTP05233 2.97  LDD0288 
Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) LDTP03871 7.34  LDD0288 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 2.37  LDD0288 
Actin nucleation-promoting factor WASL (WASL) LDTP00263 6.57  LDD0288 
Actin-related protein 3 (ACTR3) LDTP04902 2.39; 4.12; 2.34 ...  LDD0288 
Adapter molecule crk (CRK) LDTP04091 4.53; 2.42; 1.65  LDD0288 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 1.70; 3.15; 3.27  LDD0288 
AH receptor-interacting protein (AIP) LDTP00202 2.39  LDD0288 
Alpha-actinin-1 (ACTN1) LDTP02631 5.34; 2.95; 4.31  LDD0288 
Alpha-centractin (ACTR1A) LDTP04904 2.48  LDD0288 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 5.74  LDD0288 
Anamorsin (CIAPIN1) LDTP07385 0.99  LDD0288 
Ankyrin repeat and MYND domain-containing protein 2 (ANKMY2) LDTP17620 4.79  LDD0288 
Ankyrin repeat domain-containing protein 39 (ANKRD39) LDTP19320 2.14  LDD0288 
Annexin A3 (ANXA3) LDTP02620 1.41  LDD0288 
Annexin A7 (ANXA7) LDTP03030 2.27  LDD0288 
Apoptosis inhibitor 5 (API5) LDTP11575 2.96  LDD0288 
Beta-parvin (PARVB) LDTP12184 3.64  LDD0288 
Bifunctional purine biosynthesis protein ATIC (ATIC) LDTP03612 3.68; 4.03; 2.35 ...  LDD0288 
Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (ARFGEF2) LDTP14237 6.01  LDD0288 
C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9) LDTP00934 7.58; 2.88  LDD0288 
Calpain small subunit 1 (CAPNS1) LDTP02047 3.18  LDD0288 
Calponin-3 (CNN3) LDTP06383 3.14; 2.75; 2.91 ...  LDD0288 
Calumenin (CALU) LDTP00887 2.64; 2.52; 2.82 ...  LDD0288 
cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) LDTP02697 1.72  LDD0288 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 3.17; 3.36; 2.78 ...  LDD0288 
Cell cycle and apoptosis regulator protein 2 (CCAR2) LDTP08760 0.62  LDD0288 
Coatomer subunit alpha (COPA) LDTP04571 3.86  LDD0288 
Coatomer subunit beta (COPB1) LDTP04570 2.98  LDD0288 
Coatomer subunit gamma-1 (COPG1) LDTP14216 3.82  LDD0288 
Cofilin-1 (CFL1) LDTP03244 4.03; 4.86; 3.35 ...  LDD0288 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 4.05  LDD0288 
Condensin complex subunit 2 (NCAPH) LDTP06268 3.14  LDD0288 
Copper transport protein ATOX1 (ATOX1) LDTP00229 2.85  LDD0288 
Coronin-1B (CORO1B) LDTP11101 5.20  LDD0288 
Coronin-1C (CORO1C) LDTP13580 3.07  LDD0288 
Crk-like protein (CRKL) LDTP04092 4.85; 2.54; 6.82  LDD0288 
Cysteine and glycine-rich protein 1 (CSRP1) LDTP03106 6.96; 2.17; 2.53  LDD0288 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 3.49; 1.67; 3.19 ...  LDD0288 
Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2) LDTP05855 5.96  LDD0288 
Cytoplasmic FMR1-interacting protein 1 (CYFIP1) LDTP07958 3.28  LDD0288 
Cytotoxic granule associated RNA binding protein TIA1 (TIA1) LDTP03598 2.93  LDD0288 
Destrin (DSTN) LDTP04887 1.68; 9.79; 0.41  LDD0288 
DnaJ homolog subfamily A member 2 (DNAJA2) LDTP01073 4.86  LDD0288 
DnaJ homolog subfamily B member 1 (DNAJB1) LDTP03325 2.81  LDD0288 
DnaJ homolog subfamily C member 3 (DNAJC3) LDTP05789 2.88  LDD0288 
DnaJ homolog subfamily C member 8 (DNAJC8) LDTP01361 2.35  LDD0288 
Drebrin-like protein (DBNL) LDTP13399 3.02; 4.03; 2.88  LDD0288 
Dynactin subunit 1 (DCTN1) LDTP06082 1.58  LDD0288 
Dynactin subunit 2 (DCTN2) LDTP05922 2.97  LDD0288 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 6.57  LDD0288 
Dynein light chain 2, cytoplasmic (DYNLL2) LDTP10308 3.98  LDD0288 
Elongation factor 1-beta (EEF1B2) LDTP03283 3.49; 2.02; 3.70 ...  LDD0288 
Elongation factor 1-delta (EEF1D) LDTP03499 3.49; 3.53; 1.96 ...  LDD0288 
Elongation factor 1-gamma (EEF1G) LDTP03367 3.39; 2.54; 5.39  LDD0288 
Endoplasmic reticulum resident protein 29 (ERP29) LDTP03509 4.45; 2.00; 8.06  LDD0288 
Endoplasmin (HSP90B1) LDTP02734 9.55; 3.11; 2.78 ...  LDD0288 
Enhancer of mRNA-decapping protein 3 (EDC3) LDTP10299 2.67  LDD0288 
Epidermal growth factor receptor substrate 15-like 1 (EPS15L1) LDTP13097 7.29  LDD0288 
Eukaryotic translation initiation factor 1 (EIF1) LDTP03953 4.58  LDD0288 
Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX) LDTP04129 2.11  LDD0288 
Eukaryotic translation initiation factor 1b (EIF1B) LDTP16815 4.58  LDD0288 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 2.65  LDD0288 
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) LDTP03027 2.78  LDD0288 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 7.38  LDD0288 
Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 3.15  LDD0288 
Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 1.26  LDD0288 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 10.10  LDD0288 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 3.09; 5.25  LDD0288 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 4.02  LDD0288 
Eukaryotic translation initiation factor 4H (EIF4H) LDTP06301 0.42  LDD0288 
F-actin-uncapping protein LRRC16A (CARMIL1) LDTP07261 2.00  LDD0288 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 4.65; 1.95  LDD0288 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 3.24; 3.02; 1.74 ...  LDD0288 
G antigen 2B/2C (GAGE2B; GAGE2C) LDTP17028 16.63  LDD0288 
Gelsolin (GSN) LDTP02145 19.24; 2.93; 2.86 ...  LDD0288 
General transcription factor IIF subunit 2 (GTF2F2) LDTP02703 2.31; 1.92  LDD0288 
Growth factor receptor-bound protein 2 (GRB2) LDTP05035 5.33  LDD0288 
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPVD1) LDTP06255 3.99  LDD0288 
Heat shock 70 kDa protein 1A (HSPA1A) LDTP02434 3.85; 4.84; 4.63 ...  LDD0288 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 2.14; 1.73; 0.99 ...  LDD0288 
Heat shock 70 kDa protein 4L (HSPA4L) LDTP14545 6.20  LDD0288 
Heat shock protein 105 kDa (HSPH1) LDTP09811 2.89; 3.64  LDD0288 
Heat shock protein beta-1 (HSPB1) LDTP02053 2.48; 1.87; 1.64 ...  LDD0288 
Heme-binding protein 1 (HEBP1) LDTP16078 2.26; 5.99  LDD0288 
Hepatoma-derived growth factor (HDGF) LDTP04483 1.90  LDD0288 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 2.81; 3.33  LDD0288 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 3.01; 2.44; 2.57 ...  LDD0288 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 3.33; 2.71; 2.99  LDD0288 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 3.45  LDD0288 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 2.13; 2.67; 6.97 ...  LDD0288 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 2.32; 1.93; 2.36 ...  LDD0288 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 2.53; 4.27; 2.81 ...  LDD0288 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 2.68  LDD0288 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 3.56  LDD0288 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 2.93; 3.12; 4.82 ...  LDD0288 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 2.34; 2.63; 6.21 ...  LDD0288 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 5.85  LDD0288 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 2.77; 2.21; 1.72 ...  LDD0288 
Histone H2B type 1-D (H2BC5) LDTP04822 1.12; 6.70; 3.81 ...  LDD0288 
Histone H2B type 1-L (H2BC13) LDTP11001 6.21  LDD0288 
Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) LDTP05004 1.25; 3.80  LDD0288 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 2.24; 3.54  LDD0288 
Hsc70-interacting protein (ST13) LDTP04367 16.08; 4.20; 2.87  LDD0288 
Influenza virus NS1A-binding protein (IVNS1ABP) LDTP14309 1.90  LDD0288 
Integrator complex subunit 10 (INTS10) LDTP16111 1.86  LDD0288 
IST1 homolog (IST1) LDTP04593 4.15  LDD0288 
Kinesin light chain 1 (KLC1) LDTP05533 3.79; 2.18  LDD0288 
Kinesin light chain 2 (KLC2) LDTP11695 3.79; 2.18  LDD0288 
Laminin subunit beta-2 (LAMB2) LDTP04691 5.05  LDD0288 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 3.90  LDD0288 
Large ribosomal subunit protein eL21 (RPL21) LDTP04107 2.61; 1.13; 2.95  LDD0288 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 2.38; 2.81  LDD0288 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 0.84; 6.97  LDD0288 
Large ribosomal subunit protein eL29 (RPL29) LDTP04140 2.98  LDD0288 
Large ribosomal subunit protein eL31 (RPL31) LDTP05023 6.13  LDD0288 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 4.44; 2.79  LDD0288 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 1.64  LDD0288 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 0.25; 3.85  LDD0288 
Large ribosomal subunit protein eL37 (RPL37) LDTP04943 4.30  LDD0288 
Large ribosomal subunit protein eL43 (RPL37A) LDTP04926 3.95  LDD0288 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 6.43; 4.62  LDD0288 
Large ribosomal subunit protein uL13 (RPL13A) LDTP03899 4.99; 2.20; 2.47  LDD0288 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 4.87  LDD0288 
Large ribosomal subunit protein uL15 (RPL27A) LDTP04105 2.77  LDD0288 
Large ribosomal subunit protein uL16 (RPL10) LDTP03395 2.75  LDD0288 
Large ribosomal subunit protein uL2 (RPL8) LDTP05027 2.29  LDD0288 
Large ribosomal subunit protein uL22 (RPL17) LDTP02961 2.99  LDD0288 
Large ribosomal subunit protein uL29 (RPL35) LDTP03999 3.89  LDD0288 
Large ribosomal subunit protein uL30 (RPL7) LDTP02944 4.07  LDD0288 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 5.25; 1.65; 1.53 ...  LDD0288 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 3.65; 3.88  LDD0288 
LIM domain and actin-binding protein 1 (LIMA1) LDTP13260 3.50  LDD0288 
LRP chaperone MESD (MESD) LDTP06191 2.51  LDD0288 
Macrophage-capping protein (CAPG) LDTP03877 20.00; 3.58  LDD0288 
Melanoma-associated antigen D2 (MAGED2) LDTP13657 2.79  LDD0288 
Microtubule-associated protein 4 (MAP4) LDTP03404 3.17; 0.05  LDD0288 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 0.14  LDD0288 
Muscleblind-like protein 1 (MBNL1) LDTP12478 3.46; 2.93  LDD0288 
Muscleblind-like protein 2 (MBNL2) LDTP07260 3.46; 0.94  LDD0288 
Muscleblind-like protein 3 (MBNL3) LDTP12630 2.93  LDD0288 
Myosin regulatory light chain 12B (MYL12B) LDTP00487 0.24; 2.40  LDD0288 
Myotrophin (MTPN) LDTP04819 2.47  LDD0288 
N6-adenosine-methyltransferase non-catalytic subunit (METTL14) LDTP12234 5.37  LDD0288 
Nascent polypeptide-associated complex subunit alpha (NACA) LDTP05977 0.14; 2.36  LDD0288 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 2.97; 1.47  LDD0288 
Nuclear migration protein nudC (NUDC) LDTP13817 4.89  LDD0288 
Nucleolin (NCL) LDTP02990 5.20; 3.13; 3.15 ...  LDD0288 
Nucleolysin TIAR (TIAL1) LDTP05274 2.55  LDD0288 
Nucleophosmin (NPM1) LDTP02164 2.83; 3.18; 2.50  LDD0288 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 0.77; 2.14; 2.76  LDD0288 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 6.69; 2.76  LDD0288 
Oxysterol-binding protein-related protein 11 (OSBPL11) LDTP11367 3.52  LDD0288 
Perilipin-3 (PLIN3) LDTP01021 2.24  LDD0288 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 4.04; 7.56; 3.67 ...  LDD0288 
Plastin-3 (PLS3) LDTP02692 3.25; 1.48  LDD0288 
Platelet-activating factor acetylhydrolase IB subunit beta (PAFAH1B1) LDTP04015 2.44; 3.17  LDD0288 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 3.76; 2.48; 2.84  LDD0288 
Poly(rC)-binding protein 2 (PCBP2) LDTP06367 3.43; 1.52  LDD0288 
Polyadenylate-binding protein 1 (PABPC1) LDTP02595 3.52; 2.17; 3.02 ...  LDD0288 
Polyadenylate-binding protein 4 (PABPC4) LDTP05821 2.42; 2.61  LDD0288 
Polypyrimidine tract-binding protein 1 (PTBP1) LDTP03364 2.71; 3.01  LDD0288 
Prefoldin subunit 3 (VBP1) LDTP04935 3.04  LDD0288 
Prelamin-A/C (LMNA) LDTP01932 3.42; 2.72  LDD0288 
Profilin-1 (PFN1) LDTP02218 3.31; 4.22  LDD0288 
Programmed cell death protein 5 (PDCD5) LDTP00417 3.28; 7.48  LDD0288 
Proliferating cell nuclear antigen (PCNA) LDTP02596 1.16; 2.12  LDD0288 
Protein BUD31 homolog (BUD31) LDTP03935 1.20  LDD0288 
Protein FAM118B (FAM118B) LDTP15852 2.19  LDD0288 
Protein flightless-1 homolog (FLII) LDTP05734 1.26  LDD0288 
Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) LDTP13656 8.63; 4.34; 3.05 ...  LDD0288 
Protein LSM12 (LSM12) LDTP06780 4.68  LDD0288 
Protein mago nashi homolog 2 (MAGOHB) LDTP10071 3.41  LDD0288 
Protein NipSnap homolog 3A (NIPSNAP3A) LDTP18525 3.25; 3.80  LDD0288 
Protein phosphatase 1 regulatory subunit 12A (PPP1R12A) LDTP00495 20.00  LDD0288 
Protein RCC2 (RCC2) LDTP13020 3.76  LDD0288 
Protein S100-A11 (S100A11) LDTP03620 3.80; 3.56  LDD0288 
Protein SET (SET) LDTP05277 3.58  LDD0288 
Protein SGT1 homolog (SUGT1) LDTP13935 0.84; 8.27  LDD0288 
Protein TFG (TFG) LDTP09851 4.14  LDD0288 
Protein transport protein Sec23A (SEC23A) LDTP06390 3.13; 2.22  LDD0288 
Protein transport protein Sec23B (SEC23B) LDTP06391 4.94  LDD0288 
Protein UXT (UXT) LDTP13125 2.40  LDD0288 
Putative protein FAM10A5 (ST13P5) LDTP17811 2.87  LDD0288 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 2.77  LDD0288 
Pyridoxal phosphate homeostasis protein (PLPBP) LDTP14521 0.83; 3.11  LDD0288 
Rab GDP dissociation inhibitor alpha (GDI1) LDTP03574 2.95; 4.45  LDD0288 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 4.85; 5.29; 0.99 ...  LDD0288 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 5.19  LDD0288 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 4.52; 4.11; 11.57 ...  LDD0288 
Replication protein A 70 kDa DNA-binding subunit (RPA1) LDTP03397 0.14  LDD0288 
Reticulocalbin-1 (RCN1) LDTP06352 2.06  LDD0288 
Retinoblastoma-associated protein (RB1) LDTP02146 2.76  LDD0288 
Rho GDP-dissociation inhibitor 1 (ARHGDIA) LDTP04510 5.61; 3.59; 0.12 ...  LDD0288 
Rho guanine nucleotide exchange factor 2 (ARHGEF2) LDTP09950 1.34  LDD0288 
Ribosome biogenesis protein WDR12 (WDR12) LDTP11625 3.84  LDD0288 
RNA-binding protein 3 (RBM3) LDTP05226 2.40; 2.61  LDD0288 
RNA-binding protein EWS (EWSR1) LDTP05318 6.30  LDD0288 
RNA-binding protein FUS (FUS) LDTP03775 3.24; 3.09  LDD0288 
Serine/arginine-rich splicing factor 2 (SRSF2) LDTP05280 2.63  LDD0288 
Serine/arginine-rich splicing factor 8 (SRSF8) LDTP11117 2.63  LDD0288 
Serpin H1 (SERPINH1) LDTP04363 1.73  LDD0288 
Single-stranded DNA-binding protein, mitochondrial (SSBP1) LDTP05437 2.41; 4.01; 3.81 ...  LDD0288 
Small acidic protein (SMAP) LDTP19007 3.57  LDD0288 
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) LDTP00862 0.34; 4.80; 1.75 ...  LDD0288 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 2.65; 1.40; 3.00  LDD0288 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 5.80; 2.88  LDD0288 
Small ribosomal subunit protein eS19 (RPS19) LDTP03864 2.02  LDD0288 
Small ribosomal subunit protein eS24 (RPS24) LDTP05012 1.94; 3.20; 2.22  LDD0288 
Small ribosomal subunit protein eS26 (RPS26) LDTP05014 2.59  LDD0288 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 8.60; 1.73  LDD0288 
Small ribosomal subunit protein eS4, Y isoform 1 (RPS4Y1) LDTP14653 1.73  LDD0288 
Small ribosomal subunit protein eS4, Y isoform 2 (RPS4Y2) LDTP19820 1.73  LDD0288 
Small ribosomal subunit protein eS7 (RPS7) LDTP04958 2.10  LDD0288 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 5.81; 5.20; 11.04 ...  LDD0288 
Small ribosomal subunit protein uS11 (RPS14) LDTP04970 2.75  LDD0288 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 3.25  LDD0288 
Small ribosomal subunit protein uS13 (RPS18) LDTP04972 7.17; 1.80; 0.84  LDD0288 
Small ribosomal subunit protein uS15 (RPS13) LDTP04974 2.37; 3.35; 3.30  LDD0288 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 2.57; 2.61  LDD0288 
Small ribosomal subunit protein uS2 (RPSA) LDTP02312 2.82  LDD0288 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 2.71; 4.20; 2.90  LDD0288 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 2.56; 2.86  LDD0288 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 3.61; 2.69  LDD0288 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 2.92  LDD0288 
Splicing factor YJU2 (YJU2) LDTP11317 7.35  LDD0288 
Src substrate cortactin (CTTN) LDTP06094 2.90; 3.77; 3.51 ...  LDD0288 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 4.14; 1.32; 1.60 ...  LDD0288 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 7.45; 2.88; 3.86 ...  LDD0288 
Stromal cell-derived factor 2-like protein 1 (SDF2L1) LDTP16047 4.71  LDD0288 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 4.63; 3.94  LDD0288 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 7.53  LDD0288 
Structural maintenance of chromosomes protein 4 (SMC4) LDTP12606 3.28  LDD0288 
T-complex protein 1 subunit beta (CCT2) LDTP05113 5.26; 4.49  LDD0288 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 2.84; 0.11  LDD0288 
T-complex protein 1 subunit eta (CCT7) LDTP10990 0.65  LDD0288 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 3.60; 2.46  LDD0288 
T-complex protein 1 subunit theta (CCT8) LDTP04390 2.99; 1.98; 1.81 ...  LDD0288 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 4.37  LDD0288 
T-complex protein 1 subunit zeta-2 (CCT6B) LDTP09777 4.37  LDD0288 
Tetratricopeptide repeat protein 1 (TTC1) LDTP15840 4.39  LDD0288 
Tetratricopeptide repeat protein 4 (TTC4) LDTP01678 2.42  LDD0288 
Transcription elongation factor A protein 1 (TCEA1) LDTP03209 7.08  LDD0288 
Transcription elongation factor SPT6 (SUPT6H) LDTP07928 4.50  LDD0288 
Transgelin-2 (TAGLN2) LDTP03846 6.46; 4.18; 3.23  LDD0288 
Translation initiation factor eIF2B subunit delta (EIF2B4) LDTP13318 3.50  LDD0288 
Translationally-controlled tumor protein (TPT1) LDTP02683 7.01; 1.94  LDD0288 
Transmembrane glycoprotein NMB (GPNMB) LDTP06237 6.05  LDD0288 
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WDR6) LDTP12296 2.92  LDD0288 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 4.39  LDD0288 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 4.39  LDD0288 
Tubulin beta chain (TUBB) LDTP02205 3.89; 3.15; 1.44 ...  LDD0288 
Tubulin beta-2A chain (TUBB2A) LDTP05998 20.00; 2.10; 2.86 ...  LDD0288 
Tubulin beta-2B chain (TUBB2B) LDTP11277 3.60; 2.86; 2.34 ...  LDD0288 
Tubulin beta-3 chain (TUBB3) LDTP05904 2.24; 3.17; 8.06 ...  LDD0288 
Tubulin beta-4A chain (TUBB4A) LDTP02037 2.48; 3.41; 2.57 ...  LDD0288 
Tubulin beta-4B chain (TUBB4B) LDTP05076 1.36; 2.40; 2.29 ...  LDD0288 
Tubulin beta-6 chain (TUBB6) LDTP11233 2.84; 2.67; 1.78 ...  LDD0288 
Tubulin gamma-1 chain (TUBG1) LDTP03213 2.67  LDD0288 
Tubulin gamma-2 chain (TUBG2) LDTP12512 2.67  LDD0288 
Tubulin-folding cofactor B (TBCB) LDTP10860 5.08; 3.00  LDD0288 
U6 snRNA-associated Sm-like protein LSm2 (LSM2) LDTP13946 3.55  LDD0288 
Ubiquilin-1 (UBQLN1) LDTP13626 2.37  LDD0288 
Ubiquitin-associated protein 2-like (UBAP2L) LDTP06060 3.07  LDD0288 
Ubiquitin-fold modifier 1 (UFM1) LDTP04946 5.00  LDD0288 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 2.68  LDD0288 
Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) LDTP11534 1.76  LDD0288 
Vacuolar fusion protein CCZ1 homolog (CCZ1) LDTP14797 1.70  LDD0288 
Vasodilator-stimulated phosphoprotein (VASP) LDTP04372 4.00  LDD0288 
Vimentin (VIM) LDTP02297 2.76; 2.67; 1.86 ...  LDD0288 
Vinculin (VCL) LDTP02946 5.71; 0.95; 3.21  LDD0288 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 1.72  LDD0288 
WD repeat-containing protein 1 (WDR1) LDTP01118 3.68; 3.03; 7.11 ...  LDD0288 
WD repeat-containing protein 5 (WDR5) LDTP04948 1.89  LDD0288 
WW domain-binding protein 2 (WBP2) LDTP10033 2.78; 2.29; 5.61  LDD0288 
Zinc finger CCHC domain-containing protein 8 (ZCCHC8) LDTP07496 0.87  LDD0288 
Zyxin (ZYX) LDTP06507 9.93  LDD0288 
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Full Information of The Labelling Profiles of This Competitor

HHS-482

Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 50 uM
Quantitative Method SILAC
Competitor Name JWB150
Competitor Concentration 50 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Skin
Disease Model Melanoma [ICD-11:2C82]
Model Name Human melanoma cell lysate (DM93)
Interaction Atlas ID  LDD0288  Download The Altas

References

1 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.