Details of the Target

General Information of Target

Target ID LDTP06532
Target Name 26S proteasome non-ATPase regulatory subunit 5 (PSMD5)
Gene Name PSMD5
Gene ID 5711
Synonyms
KIAA0072; 26S proteasome non-ATPase regulatory subunit 5; 26S protease subunit S5 basic; 26S proteasome subunit S5B
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREK
TTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEI
LNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDI
VRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHG
RQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKV
FEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIR
CLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTA
IANQPWAQKLMFNSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLR
LRTYLSEGPYYVKPVSTTAVEGAE
Target Bioclass
Enzyme
Family
Proteasome subunit S5B/HSM3 family
Function
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5.
Uniprot ID
Q16401
Ensemble ID
ENST00000210313.8
HGNC ID
HGNC:9563

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CAL51 SNV: p.A13V .
HEC1 SNV: p.L84P DBIA    Probe Info 
HGC27 SNV: p.E487K DBIA    Probe Info 
KMCH1 SNV: p.I190M DBIA    Probe Info 
KPNYN SNV: p.V314I DBIA    Probe Info 
KU1919 SNV: p.V314I DBIA    Probe Info 
MOLT4 SNV: p.A470T IA-alkyne    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 20 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
A-EBA
 Probe Info  		3.34  LDD0215  [1]
TH211
 Probe Info  		Y440(12.94); Y478(10.45)  LDD0260  [2]
IPM
 Probe Info  		N.A.  LDD0241  [3]
m-APA
 Probe Info  		11.85  LDD0403  [4]
BTD
 Probe Info  		C412(0.76)  LDD2089  [5]
HHS-482
 Probe Info  		Y478(5.43)  LDD0288  [6]
HHS-475
 Probe Info  		Y491(0.93); Y478(0.96)  LDD0264  [7]
DBIA
 Probe Info  		C290(0.78); C412(0.79); C64(0.92)  LDD0531  [8]
4-Iodoacetamidophenylacetylene
 Probe Info  		C361(0.00); C290(0.00); C412(0.00); C64(0.00)  LDD0038  [9]
IA-alkyne
 Probe Info  		C227(0.00); C361(0.00); C290(0.00); C412(0.00)  LDD0036  [9]
IPIAA_L
 Probe Info  		N.A.  LDD0031  [10]
Lodoacetamide azide
 Probe Info  		C227(0.00); C361(0.00); C290(0.00); C412(0.00)  LDD0037  [9]
JW-RF-010
 Probe Info  		C133(0.00); C64(0.00); C412(0.00)  LDD0026  [11]
TFBX
 Probe Info  		N.A.  LDD0027  [11]
Compound 10
 Probe Info  		N.A.  LDD2216  [12]
Acrolein
 Probe Info  		C290(0.00); C412(0.00); H26(0.00); C64(0.00)  LDD0217  [13]
Methacrolein
 Probe Info  		C290(0.00); C412(0.00)  LDD0218  [13]
W1
 Probe Info  		C412(0.00); C64(0.00)  LDD0236  [3]
NAIA_5
 Probe Info  		C227(0.00); C64(0.00); C412(0.00); C133(0.00)  LDD2223  [14]
HHS-465
 Probe Info  		N.A.  LDD2240  [15]
PAL-AfBPP Probe
Click To Hide/Show 7 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FFF probe11
 Probe Info  		5.28  LDD0472  [16]
FFF probe13
 Probe Info  		6.79  LDD0476  [16]
FFF probe3
 Probe Info  		6.18  LDD0465  [16]
STS-2
 Probe Info  		N.A.  LDD0138  [17]
VE-P
 Probe Info  		N.A.  LDD0396  [18]
DA-2
 Probe Info  		N.A.  LDD0070  [19]
STS-1
 Probe Info  		N.A.  LDD0068  [20]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C412(1.02)  LDD2130  [5]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C412(1.09); C133(1.06)  LDD2117  [5]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C412(1.03)  LDD2132  [5]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C64(0.71); C412(0.76)  LDD2131  [5]
 LDCM0214  AC1 HCT 116 C290(0.78); C412(0.79); C64(0.92)  LDD0531  [8]
 LDCM0215  AC10 HCT 116 C412(1.12); C64(0.95)  LDD0532  [8]
 LDCM0216  AC100 HCT 116 C290(1.07); C412(1.19)  LDD0533  [8]
 LDCM0217  AC101 HCT 116 C290(0.88); C412(1.09)  LDD0534  [8]
 LDCM0218  AC102 HCT 116 C290(0.99); C412(0.83)  LDD0535  [8]
 LDCM0219  AC103 HCT 116 C290(0.83); C412(0.95)  LDD0536  [8]
 LDCM0220  AC104 HCT 116 C290(1.03); C412(1.07)  LDD0537  [8]
 LDCM0221  AC105 HCT 116 C290(0.95); C412(0.94)  LDD0538  [8]
 LDCM0222  AC106 HCT 116 C290(0.78); C412(0.97)  LDD0539  [8]
 LDCM0223  AC107 HCT 116 C290(0.84); C412(1.00)  LDD0540  [8]
 LDCM0224  AC108 HCT 116 C290(0.91); C412(0.79)  LDD0541  [8]
 LDCM0225  AC109 HCT 116 C290(1.27); C412(1.00)  LDD0542  [8]
 LDCM0226  AC11 HCT 116 C412(1.04); C64(0.97)  LDD0543  [8]
 LDCM0227  AC110 HCT 116 C290(0.80); C412(0.88)  LDD0544  [8]
 LDCM0228  AC111 HCT 116 C290(0.77); C412(0.89)  LDD0545  [8]
 LDCM0229  AC112 HCT 116 C290(0.78); C412(0.77)  LDD0546  [8]
 LDCM0230  AC113 HCT 116 C290(0.78); C412(1.26)  LDD0547  [8]
 LDCM0231  AC114 HCT 116 C290(0.86); C412(0.88)  LDD0548  [8]
 LDCM0232  AC115 HCT 116 C290(0.71); C412(0.93)  LDD0549  [8]
 LDCM0233  AC116 HCT 116 C290(0.71); C412(1.09)  LDD0550  [8]
 LDCM0234  AC117 HCT 116 C290(0.93); C412(0.91)  LDD0551  [8]
 LDCM0235  AC118 HCT 116 C290(0.95); C412(0.96)  LDD0552  [8]
 LDCM0236  AC119 HCT 116 C290(0.85); C412(0.86)  LDD0553  [8]
 LDCM0237  AC12 HCT 116 C412(1.23); C64(1.02)  LDD0554  [8]
 LDCM0238  AC120 HCT 116 C290(0.83); C412(1.01)  LDD0555  [8]
 LDCM0239  AC121 HCT 116 C290(0.94); C412(0.76)  LDD0556  [8]
 LDCM0240  AC122 HCT 116 C290(0.84); C412(0.98)  LDD0557  [8]
 LDCM0241  AC123 HCT 116 C290(0.74); C412(0.83)  LDD0558  [8]
 LDCM0242  AC124 HCT 116 C290(1.07); C412(0.98)  LDD0559  [8]
 LDCM0243  AC125 HCT 116 C290(0.95); C412(1.03)  LDD0560  [8]
 LDCM0244  AC126 HCT 116 C290(0.82); C412(0.95)  LDD0561  [8]
 LDCM0245  AC127 HCT 116 C290(0.93); C412(0.99)  LDD0562  [8]
 LDCM0246  AC128 HCT 116 C290(1.06); C412(0.90)  LDD0563  [8]
 LDCM0247  AC129 HCT 116 C290(1.15); C412(1.09)  LDD0564  [8]
 LDCM0249  AC130 HCT 116 C290(1.15); C412(0.95)  LDD0566  [8]
 LDCM0250  AC131 HCT 116 C290(1.12); C412(1.18)  LDD0567  [8]
 LDCM0251  AC132 HCT 116 C290(1.16); C412(1.04)  LDD0568  [8]
 LDCM0252  AC133 HCT 116 C290(1.15); C412(0.94)  LDD0569  [8]
 LDCM0253  AC134 HCT 116 C290(1.12); C412(0.90)  LDD0570  [8]
 LDCM0254  AC135 HCT 116 C290(1.12); C412(1.05)  LDD0571  [8]
 LDCM0255  AC136 HCT 116 C290(1.21); C412(1.07)  LDD0572  [8]
 LDCM0256  AC137 HCT 116 C290(0.95); C412(0.98)  LDD0573  [8]
 LDCM0257  AC138 HCT 116 C290(0.91); C412(0.72)  LDD0574  [8]
 LDCM0258  AC139 HCT 116 C290(1.11); C412(0.93)  LDD0575  [8]
 LDCM0259  AC14 HCT 116 C412(1.19); C64(0.99)  LDD0576  [8]
 LDCM0260  AC140 HCT 116 C290(1.22); C412(0.84)  LDD0577  [8]
 LDCM0261  AC141 HCT 116 C290(1.23); C412(0.76)  LDD0578  [8]
 LDCM0262  AC142 HCT 116 C290(1.08); C412(0.89)  LDD0579  [8]
 LDCM0263  AC143 HCT 116 C290(0.70)  LDD0580  [8]
 LDCM0264  AC144 HCT 116 C290(0.67)  LDD0581  [8]
 LDCM0265  AC145 HCT 116 C290(0.93)  LDD0582  [8]
 LDCM0266  AC146 HCT 116 C290(0.73)  LDD0583  [8]
 LDCM0267  AC147 HCT 116 C290(1.00)  LDD0584  [8]
 LDCM0268  AC148 HCT 116 C290(0.63)  LDD0585  [8]
 LDCM0269  AC149 HCT 116 C290(0.71)  LDD0586  [8]
 LDCM0270  AC15 HCT 116 C64(0.93); C412(1.28)  LDD0587  [8]
 LDCM0271  AC150 HCT 116 C290(0.84)  LDD0588  [8]
 LDCM0272  AC151 HCT 116 C290(0.86)  LDD0589  [8]
 LDCM0273  AC152 HCT 116 C290(0.61)  LDD0590  [8]
 LDCM0274  AC153 HCT 116 C290(0.56)  LDD0591  [8]
 LDCM0621  AC154 HCT 116 C290(0.71)  LDD2158  [8]
 LDCM0622  AC155 HCT 116 C290(0.83)  LDD2159  [8]
 LDCM0623  AC156 HCT 116 C290(0.76)  LDD2160  [8]
 LDCM0624  AC157 HCT 116 C290(0.72)  LDD2161  [8]
 LDCM0276  AC17 HCT 116 C412(0.97); C290(0.99)  LDD0593  [8]
 LDCM0277  AC18 HCT 116 C412(0.83); C290(1.10)  LDD0594  [8]
 LDCM0278  AC19 HCT 116 C412(0.85); C290(1.14)  LDD0595  [8]
 LDCM0279  AC2 HCT 116 C290(0.89); C412(1.06); C64(1.06)  LDD0596  [8]
 LDCM0280  AC20 HCT 116 C412(0.89); C290(1.03)  LDD0597  [8]
 LDCM0281  AC21 HCT 116 C412(0.85); C290(1.09)  LDD0598  [8]
 LDCM0282  AC22 HCT 116 C412(0.90); C290(0.95)  LDD0599  [8]
 LDCM0283  AC23 HCT 116 C412(0.87); C290(1.14)  LDD0600  [8]
 LDCM0284  AC24 HCT 116 C290(0.88); C412(0.91)  LDD0601  [8]
 LDCM0285  AC25 HCT 116 C133(0.73); C290(0.86); C412(0.94); C64(0.94)  LDD0602  [8]
 LDCM0286  AC26 HCT 116 C133(0.56); C412(0.74); C64(0.87); C290(0.88)  LDD0603  [8]
 LDCM0287  AC27 HCT 116 C133(0.62); C412(0.85); C64(0.88); C290(0.92)  LDD0604  [8]
 LDCM0288  AC28 HCT 116 C133(0.48); C290(0.70); C412(0.75); C64(0.81)  LDD0605  [8]
 LDCM0289  AC29 HCT 116 C133(0.50); C64(0.60); C412(0.75); C290(0.84)  LDD0606  [8]
 LDCM0290  AC3 HCT 116 C64(0.93); C290(0.99); C412(1.01)  LDD0607  [8]
 LDCM0291  AC30 HCT 116 C133(0.59); C64(0.64); C412(0.74); C290(0.77)  LDD0608  [8]
 LDCM0292  AC31 HCT 116 C133(0.68); C412(0.70); C290(0.76); C64(0.77)  LDD0609  [8]
 LDCM0293  AC32 HCT 116 C133(0.58); C412(0.60); C290(0.66); C64(0.71)  LDD0610  [8]
 LDCM0294  AC33 HCT 116 C290(0.72); C412(0.83); C133(0.86); C64(0.98)  LDD0611  [8]
 LDCM0295  AC34 HCT 116 C290(0.72); C64(0.76); C412(0.87); C133(1.15)  LDD0612  [8]
 LDCM0296  AC35 HCT 116 C64(1.14); C290(1.51)  LDD0613  [8]
 LDCM0297  AC36 HCT 116 C64(1.17); C290(1.18)  LDD0614  [8]
 LDCM0298  AC37 HCT 116 C64(1.13); C290(1.21)  LDD0615  [8]
 LDCM0299  AC38 HCT 116 C64(1.19); C290(1.52)  LDD0616  [8]
 LDCM0300  AC39 HCT 116 C290(1.06); C64(1.10)  LDD0617  [8]
 LDCM0301  AC4 HCT 116 C64(0.84); C290(0.97); C412(0.99)  LDD0618  [8]
 LDCM0302  AC40 HCT 116 C290(0.92); C64(1.00)  LDD0619  [8]
 LDCM0303  AC41 HCT 116 C290(1.08); C64(1.14)  LDD0620  [8]
 LDCM0304  AC42 HCT 116 C64(1.08); C290(1.12)  LDD0621  [8]
 LDCM0305  AC43 HCT 116 C290(0.95); C64(1.01)  LDD0622  [8]
 LDCM0306  AC44 HCT 116 C64(1.06); C290(1.15)  LDD0623  [8]
 LDCM0307  AC45 HCT 116 C64(0.91); C290(1.00)  LDD0624  [8]
 LDCM0308  AC46 HCT 116 C290(0.86); C64(0.95)  LDD0625  [8]
 LDCM0309  AC47 HCT 116 C290(0.86); C64(0.95)  LDD0626  [8]
 LDCM0310  AC48 HCT 116 C290(0.69); C64(0.91)  LDD0627  [8]
 LDCM0311  AC49 HCT 116 C290(0.73); C64(0.85)  LDD0628  [8]
 LDCM0312  AC5 HCT 116 C412(0.88); C290(0.90); C64(0.98)  LDD0629  [8]
 LDCM0313  AC50 HCT 116 C290(0.74); C64(0.79)  LDD0630  [8]
 LDCM0314  AC51 HCT 116 C64(0.89); C290(1.06)  LDD0631  [8]
 LDCM0315  AC52 HCT 116 C290(0.92); C64(0.93)  LDD0632  [8]
 LDCM0316  AC53 HCT 116 C290(0.91); C64(1.13)  LDD0633  [8]
 LDCM0317  AC54 HCT 116 C290(0.87); C64(0.91)  LDD0634  [8]
 LDCM0318  AC55 HCT 116 C290(0.71); C64(1.42)  LDD0635  [8]
 LDCM0319  AC56 HCT 116 C290(0.62); C64(1.03)  LDD0636  [8]
 LDCM0320  AC57 HCT 116 C64(0.89); C290(1.21); C133(1.46)  LDD0637  [8]
 LDCM0321  AC58 HCT 116 C64(1.05); C133(1.20); C290(1.28)  LDD0638  [8]
 LDCM0322  AC59 HCT 116 C290(0.86); C64(1.01); C133(1.13)  LDD0639  [8]
 LDCM0323  AC6 HCT 116 C64(0.88); C412(0.92)  LDD0640  [8]
 LDCM0324  AC60 HCT 116 C290(0.78); C133(0.99); C64(1.01)  LDD0641  [8]
 LDCM0325  AC61 HCT 116 C64(0.93); C133(1.04); C290(1.22)  LDD0642  [8]
 LDCM0326  AC62 HCT 116 C64(0.98); C290(0.98); C133(1.09)  LDD0643  [8]
 LDCM0327  AC63 HCT 116 C290(0.92); C133(0.93); C64(1.04)  LDD0644  [8]
 LDCM0328  AC64 HCT 116 C290(0.93); C64(1.09); C133(1.14)  LDD0645  [8]
 LDCM0329  AC65 HCT 116 C133(0.85); C290(0.91); C64(0.97)  LDD0646  [8]
 LDCM0330  AC66 HCT 116 C64(0.84); C133(1.00); C290(1.06)  LDD0647  [8]
 LDCM0331  AC67 HCT 116 C64(0.85); C290(0.90); C133(1.07)  LDD0648  [8]
 LDCM0332  AC68 HCT 116 C64(0.85); C412(0.87); C290(1.04)  LDD0649  [8]
 LDCM0333  AC69 HCT 116 C64(0.71); C412(0.81); C290(1.28)  LDD0650  [8]
 LDCM0334  AC7 HCT 116 C64(0.89); C412(1.08)  LDD0651  [8]
 LDCM0335  AC70 HCT 116 C64(0.67); C412(0.67); C290(0.96)  LDD0652  [8]
 LDCM0336  AC71 HCT 116 C412(0.88); C64(0.93); C290(1.18)  LDD0653  [8]
 LDCM0337  AC72 HCT 116 C64(0.88); C412(0.91); C290(0.94)  LDD0654  [8]
 LDCM0338  AC73 HCT 116 C64(0.67); C412(0.72); C290(0.77)  LDD0655  [8]
 LDCM0339  AC74 HCT 116 C64(0.62); C412(0.75); C290(1.14)  LDD0656  [8]
 LDCM0340  AC75 HCT 116 C64(0.63); C412(0.66); C290(0.79)  LDD0657  [8]
 LDCM0341  AC76 HCT 116 C412(0.85); C64(0.86); C290(1.07)  LDD0658  [8]
 LDCM0342  AC77 HCT 116 C412(0.78); C64(0.84); C290(0.94)  LDD0659  [8]
 LDCM0343  AC78 HCT 116 C64(0.74); C412(0.81); C290(1.03)  LDD0660  [8]
 LDCM0344  AC79 HCT 116 C412(0.86); C290(0.90); C64(0.98)  LDD0661  [8]
 LDCM0345  AC8 HCT 116 C64(0.86); C412(1.12)  LDD0662  [8]
 LDCM0346  AC80 HCT 116 C290(0.77); C412(0.84); C64(0.86)  LDD0663  [8]
 LDCM0347  AC81 HCT 116 C412(0.77); C64(0.79); C290(1.23)  LDD0664  [8]
 LDCM0348  AC82 HCT 116 C64(0.56); C412(0.68); C290(1.00)  LDD0665  [8]
 LDCM0349  AC83 HCT 116 C290(0.63); C412(0.74)  LDD0666  [8]
 LDCM0350  AC84 HCT 116 C412(0.69); C290(0.78)  LDD0667  [8]
 LDCM0351  AC85 HCT 116 C412(0.74); C290(0.83)  LDD0668  [8]
 LDCM0352  AC86 HCT 116 C290(0.77); C412(0.94)  LDD0669  [8]
 LDCM0353  AC87 HCT 116 C290(0.83); C412(0.89)  LDD0670  [8]
 LDCM0354  AC88 HCT 116 C290(0.80); C412(0.88)  LDD0671  [8]
 LDCM0355  AC89 HCT 116 C290(0.74); C412(0.87)  LDD0672  [8]
 LDCM0357  AC90 HCT 116 C290(0.92); C412(1.10)  LDD0674  [8]
 LDCM0358  AC91 HCT 116 C412(0.75); C290(1.00)  LDD0675  [8]
 LDCM0359  AC92 HCT 116 C412(0.80); C290(0.85)  LDD0676  [8]
 LDCM0360  AC93 HCT 116 C290(0.76); C412(0.81)  LDD0677  [8]
 LDCM0361  AC94 HCT 116 C412(0.71); C290(0.99)  LDD0678  [8]
 LDCM0362  AC95 HCT 116 C290(0.74); C412(0.95)  LDD0679  [8]
 LDCM0363  AC96 HCT 116 C412(0.73); C290(1.01)  LDD0680  [8]
 LDCM0364  AC97 HCT 116 C290(0.69); C412(0.79)  LDD0681  [8]
 LDCM0365  AC98 HCT 116 C290(0.77); C412(1.06)  LDD0682  [8]
 LDCM0366  AC99 HCT 116 C290(0.89); C412(1.04)  LDD0683  [8]
 LDCM0545  Acetamide MDA-MB-231 C412(0.55)  LDD2138  [5]
 LDCM0248  AKOS034007472 HCT 116 C412(1.07); C64(1.07)  LDD0565  [8]
 LDCM0356  AKOS034007680 HCT 116 C64(0.95); C412(0.97)  LDD0673  [8]
 LDCM0275  AKOS034007705 HCT 116 C64(0.78); C412(1.17)  LDD0592  [8]
 LDCM0156  Aniline NCI-H1299 11.85  LDD0403  [4]
 LDCM0020  ARS-1620 HCC44 C290(0.90)  LDD2171  [8]
 LDCM0108  Chloroacetamide HeLa C290(0.00); C412(0.00); C64(0.00); H26(0.00)  LDD0222  [13]
 LDCM0367  CL1 HCT 116 C412(0.88); C64(0.99); C133(1.01); C290(1.20)  LDD0684  [8]
 LDCM0368  CL10 HCT 116 C290(0.70); C412(0.72); C64(0.92); C133(1.15)  LDD0685  [8]
 LDCM0369  CL100 HCT 116 C290(0.83); C64(0.87); C412(1.00)  LDD0686  [8]
 LDCM0370  CL101 HCT 116 C64(0.98); C412(1.11)  LDD0687  [8]
 LDCM0371  CL102 HCT 116 C64(0.92); C412(1.10)  LDD0688  [8]
 LDCM0372  CL103 HCT 116 C64(0.93); C412(1.27)  LDD0689  [8]
 LDCM0373  CL104 HCT 116 C64(0.88); C412(1.28)  LDD0690  [8]
 LDCM0374  CL105 HCT 116 C412(0.76); C290(0.94)  LDD0691  [8]
 LDCM0375  CL106 HCT 116 C412(0.70); C290(1.66)  LDD0692  [8]
 LDCM0376  CL107 HCT 116 C412(0.77); C290(1.26)  LDD0693  [8]
 LDCM0377  CL108 HCT 116 C412(0.73); C290(1.11)  LDD0694  [8]
 LDCM0378  CL109 HCT 116 C412(0.77); C290(1.08)  LDD0695  [8]
 LDCM0379  CL11 HCT 116 C290(0.77); C412(0.81); C64(0.99); C133(1.52)  LDD0696  [8]
 LDCM0380  CL110 HCT 116 C412(0.72); C290(0.98)  LDD0697  [8]
 LDCM0381  CL111 HCT 116 C412(0.79); C290(0.97)  LDD0698  [8]
 LDCM0382  CL112 HCT 116 C64(0.84); C133(0.84); C412(0.96); C290(0.99)  LDD0699  [8]
 LDCM0383  CL113 HCT 116 C64(0.61); C412(0.74); C290(0.76); C133(0.93)  LDD0700  [8]
 LDCM0384  CL114 HCT 116 C64(0.55); C412(0.76); C290(0.80); C133(0.81)  LDD0701  [8]
 LDCM0385  CL115 HCT 116 C64(0.72); C290(0.77); C412(0.88); C133(0.88)  LDD0702  [8]
 LDCM0386  CL116 HCT 116 C133(0.79); C64(0.83); C412(0.89); C290(0.91)  LDD0703  [8]
 LDCM0387  CL117 HCT 116 C64(0.79); C290(0.80)  LDD0704  [8]
 LDCM0388  CL118 HCT 116 C64(1.11); C290(1.14)  LDD0705  [8]
 LDCM0389  CL119 HCT 116 C64(0.91); C290(1.01)  LDD0706  [8]
 LDCM0390  CL12 HCT 116 C290(0.85); C412(0.87); C64(1.08); C133(1.32)  LDD0707  [8]
 LDCM0391  CL120 HCT 116 C290(1.16); C64(1.18)  LDD0708  [8]
 LDCM0392  CL121 HCT 116 C290(0.69); C64(0.95)  LDD0709  [8]
 LDCM0393  CL122 HCT 116 C290(0.87); C64(0.97)  LDD0710  [8]
 LDCM0394  CL123 HCT 116 C290(0.72); C64(0.77)  LDD0711  [8]
 LDCM0395  CL124 HCT 116 C290(0.70); C64(0.90)  LDD0712  [8]
 LDCM0396  CL125 HCT 116 C290(0.79); C64(0.85); C133(0.90)  LDD0713  [8]
 LDCM0397  CL126 HCT 116 C64(0.90); C133(0.93); C290(0.96)  LDD0714  [8]
 LDCM0398  CL127 HCT 116 C64(0.80); C290(0.93); C133(1.03)  LDD0715  [8]
 LDCM0399  CL128 HCT 116 C64(0.83); C133(1.19); C290(1.32)  LDD0716  [8]
 LDCM0400  CL13 HCT 116 C290(0.72); C412(0.81); C133(1.05); C64(1.18)  LDD0717  [8]
 LDCM0401  CL14 HCT 116 C412(0.78); C290(0.84); C64(0.99); C133(1.23)  LDD0718  [8]
 LDCM0402  CL15 HCT 116 C290(0.57); C412(0.78); C133(0.84); C64(1.11)  LDD0719  [8]
 LDCM0403  CL16 HCT 116 C133(0.50); C290(0.86); C412(1.15)  LDD0720  [8]
 LDCM0404  CL17 HCT 116 C412(0.83); C133(1.06); C290(1.07)  LDD0721  [8]
 LDCM0405  CL18 HCT 116 C133(0.64); C412(1.00); C290(1.02)  LDD0722  [8]
 LDCM0406  CL19 HCT 116 C290(0.84); C412(1.00); C133(1.03)  LDD0723  [8]
 LDCM0407  CL2 HCT 116 C290(0.91); C412(0.91); C133(0.96); C64(1.05)  LDD0724  [8]
 LDCM0408  CL20 HCT 116 C133(0.86); C290(1.00); C412(1.12)  LDD0725  [8]
 LDCM0409  CL21 HCT 116 C412(0.88); C290(0.97); C133(1.01)  LDD0726  [8]
 LDCM0410  CL22 HCT 116 C412(0.89); C290(1.04); C133(1.26)  LDD0727  [8]
 LDCM0411  CL23 HCT 116 C133(0.74); C290(0.83); C412(1.10)  LDD0728  [8]
 LDCM0412  CL24 HCT 116 C133(0.41); C290(1.06); C412(1.01)  LDD0729  [8]
 LDCM0413  CL25 HCT 116 C133(0.37); C290(0.79); C412(1.10)  LDD0730  [8]
 LDCM0414  CL26 HCT 116 C133(0.64); C290(0.63); C412(1.03)  LDD0731  [8]
 LDCM0415  CL27 HCT 116 C133(0.48); C290(0.93); C412(1.14)  LDD0732  [8]
 LDCM0416  CL28 HCT 116 C133(0.43); C290(0.88); C412(1.09)  LDD0733  [8]
 LDCM0417  CL29 HCT 116 C133(0.35); C290(0.97); C412(1.21)  LDD0734  [8]
 LDCM0418  CL3 HCT 116 C133(1.36); C290(0.80); C412(1.04); C64(1.04)  LDD0735  [8]
 LDCM0419  CL30 HCT 116 C133(0.44); C290(0.91); C412(1.19)  LDD0736  [8]
 LDCM0420  CL31 HCT 116 C290(0.66); C412(0.79); C64(0.96)  LDD0737  [8]
 LDCM0421  CL32 HCT 116 C290(0.55); C412(0.88); C64(1.00)  LDD0738  [8]
 LDCM0422  CL33 HCT 116 C290(0.56); C412(0.67); C64(0.95)  LDD0739  [8]
 LDCM0423  CL34 HCT 116 C290(0.59); C412(0.70); C64(0.84)  LDD0740  [8]
 LDCM0424  CL35 HCT 116 C290(0.66); C412(0.89); C64(0.79)  LDD0741  [8]
 LDCM0425  CL36 HCT 116 C290(0.68); C412(0.84); C64(0.88)  LDD0742  [8]
 LDCM0426  CL37 HCT 116 C290(0.67); C412(0.73); C64(0.99)  LDD0743  [8]
 LDCM0428  CL39 HCT 116 C290(0.67); C412(0.76); C64(1.03)  LDD0745  [8]
 LDCM0429  CL4 HCT 116 C133(1.21); C290(0.91); C412(0.87); C64(1.00)  LDD0746  [8]
 LDCM0430  CL40 HCT 116 C290(0.65); C412(0.81); C64(0.93)  LDD0747  [8]
 LDCM0431  CL41 HCT 116 C290(0.72); C412(0.73); C64(1.02)  LDD0748  [8]
 LDCM0432  CL42 HCT 116 C290(0.62); C412(0.70); C64(0.90)  LDD0749  [8]
 LDCM0433  CL43 HCT 116 C290(0.56); C412(0.68); C64(1.03)  LDD0750  [8]
 LDCM0434  CL44 HCT 116 C290(0.56); C412(0.64); C64(1.04)  LDD0751  [8]
 LDCM0435  CL45 HCT 116 C290(0.53); C412(0.70); C64(0.90)  LDD0752  [8]
 LDCM0436  CL46 HCT 116 C412(0.76); C64(0.87)  LDD0753  [8]
 LDCM0437  CL47 HCT 116 C412(1.07); C64(0.80)  LDD0754  [8]
 LDCM0438  CL48 HCT 116 C412(0.90); C64(0.86)  LDD0755  [8]
 LDCM0439  CL49 HCT 116 C412(0.82); C64(1.11)  LDD0756  [8]
 LDCM0440  CL5 HCT 116 C133(0.87); C290(1.01); C412(0.88); C64(1.26)  LDD0757  [8]
 LDCM0441  CL50 HCT 116 C412(0.82); C64(1.01)  LDD0758  [8]
 LDCM0442  CL51 HCT 116 C412(0.90); C64(1.02)  LDD0759  [8]
 LDCM0443  CL52 HCT 116 C412(0.99); C64(0.98)  LDD0760  [8]
 LDCM0444  CL53 HCT 116 C412(0.82); C64(0.83)  LDD0761  [8]
 LDCM0445  CL54 HCT 116 C412(0.79); C64(0.97)  LDD0762  [8]
 LDCM0446  CL55 HCT 116 C412(0.70); C64(0.85)  LDD0763  [8]
 LDCM0447  CL56 HCT 116 C412(0.80); C64(0.87)  LDD0764  [8]
 LDCM0448  CL57 HCT 116 C412(0.84); C64(0.93)  LDD0765  [8]
 LDCM0449  CL58 HCT 116 C412(0.81); C64(0.96)  LDD0766  [8]
 LDCM0450  CL59 HCT 116 C412(0.72); C64(1.06)  LDD0767  [8]
 LDCM0451  CL6 HCT 116 C133(0.71); C290(0.72); C412(0.90); C64(1.22)  LDD0768  [8]
 LDCM0452  CL60 HCT 116 C412(0.84); C64(0.99)  LDD0769  [8]
 LDCM0453  CL61 HCT 116 C290(0.99); C412(0.77); C64(0.85)  LDD0770  [8]
 LDCM0454  CL62 HCT 116 C290(0.87); C412(0.78); C64(0.88)  LDD0771  [8]
 LDCM0455  CL63 HCT 116 C290(0.73); C412(0.86); C64(0.83)  LDD0772  [8]
 LDCM0456  CL64 HCT 116 C290(0.80); C412(0.74); C64(0.99)  LDD0773  [8]
 LDCM0457  CL65 HCT 116 C290(0.85); C412(0.90); C64(1.17)  LDD0774  [8]
 LDCM0458  CL66 HCT 116 C290(0.64); C412(0.85); C64(1.11)  LDD0775  [8]
 LDCM0459  CL67 HCT 116 C290(0.72); C412(0.79); C64(1.18)  LDD0776  [8]
 LDCM0460  CL68 HCT 116 C290(0.89); C412(0.85); C64(0.95)  LDD0777  [8]
 LDCM0461  CL69 HCT 116 C290(0.62); C412(0.76); C64(0.82)  LDD0778  [8]
 LDCM0462  CL7 HCT 116 C133(0.71); C290(0.75); C412(0.81); C64(1.38)  LDD0779  [8]
 LDCM0463  CL70 HCT 116 C290(0.68); C412(0.82); C64(0.93)  LDD0780  [8]
 LDCM0464  CL71 HCT 116 C290(0.81); C412(0.66); C64(0.89)  LDD0781  [8]
 LDCM0465  CL72 HCT 116 C290(1.01); C412(0.85); C64(0.80)  LDD0782  [8]
 LDCM0466  CL73 HCT 116 C290(0.66); C412(0.78); C64(0.93)  LDD0783  [8]
 LDCM0467  CL74 HCT 116 C290(0.69); C412(0.86); C64(1.13)  LDD0784  [8]
 LDCM0469  CL76 HCT 116 C290(0.82); C412(1.08); C64(0.73)  LDD0786  [8]
 LDCM0470  CL77 HCT 116 C290(0.79); C412(1.21); C64(0.80)  LDD0787  [8]
 LDCM0471  CL78 HCT 116 C290(0.93); C412(1.05); C64(0.88)  LDD0788  [8]
 LDCM0472  CL79 HCT 116 C290(0.81); C412(1.07); C64(0.82)  LDD0789  [8]
 LDCM0473  CL8 HCT 116 C133(0.98); C290(0.63); C412(0.94); C64(1.13)  LDD0790  [8]
 LDCM0474  CL80 HCT 116 C290(0.84); C412(0.98); C64(0.77)  LDD0791  [8]
 LDCM0475  CL81 HCT 116 C290(0.92); C412(1.01); C64(0.86)  LDD0792  [8]
 LDCM0476  CL82 HCT 116 C290(0.84); C412(0.73); C64(0.77)  LDD0793  [8]
 LDCM0477  CL83 HCT 116 C290(0.77); C412(0.77); C64(0.75)  LDD0794  [8]
 LDCM0478  CL84 HCT 116 C290(0.64); C412(0.80); C64(0.73)  LDD0795  [8]
 LDCM0479  CL85 HCT 116 C290(0.76); C412(0.85); C64(0.76)  LDD0796  [8]
 LDCM0480  CL86 HCT 116 C290(0.91); C412(0.98); C64(0.77)  LDD0797  [8]
 LDCM0481  CL87 HCT 116 C290(0.82); C412(0.88); C64(0.83)  LDD0798  [8]
 LDCM0482  CL88 HCT 116 C290(0.84); C412(0.97); C64(0.90)  LDD0799  [8]
 LDCM0483  CL89 HCT 116 C290(0.73); C412(0.78); C64(0.80)  LDD0800  [8]
 LDCM0484  CL9 HCT 116 C133(0.60); C290(0.85); C412(0.73); C64(1.03)  LDD0801  [8]
 LDCM0485  CL90 HCT 116 C290(1.23); C412(1.03); C64(0.93)  LDD0802  [8]
 LDCM0486  CL91 HCT 116 C290(0.65); C412(1.15); C64(1.16)  LDD0803  [8]
 LDCM0487  CL92 HCT 116 C290(0.91); C412(1.01); C64(0.98)  LDD0804  [8]
 LDCM0488  CL93 HCT 116 C290(1.05); C412(0.99); C64(0.83)  LDD0805  [8]
 LDCM0489  CL94 HCT 116 C290(0.85); C412(0.84); C64(0.71)  LDD0806  [8]
 LDCM0490  CL95 HCT 116 C290(0.89); C412(0.94); C64(0.93)  LDD0807  [8]
 LDCM0491  CL96 HCT 116 C290(0.83); C412(0.99); C64(0.73)  LDD0808  [8]
 LDCM0492  CL97 HCT 116 C290(0.78); C412(1.02); C64(0.76)  LDD0809  [8]
 LDCM0493  CL98 HCT 116 C290(0.85); C412(1.20); C64(1.00)  LDD0810  [8]
 LDCM0494  CL99 HCT 116 C290(0.87); C412(1.17); C64(0.83)  LDD0811  [8]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C412(1.66)  LDD1702  [5]
 LDCM0468  Fragment33 HCT 116 C290(0.73); C412(0.70); C64(0.86)  LDD0785  [8]
 LDCM0427  Fragment51 HCT 116 C290(0.60); C412(0.56); C64(0.86)  LDD0744  [8]
 LDCM0116  HHS-0101 DM93 Y491(0.93); Y478(0.96)  LDD0264  [7]
 LDCM0117  HHS-0201 DM93 Y478(0.87); Y491(1.03)  LDD0265  [7]
 LDCM0118  HHS-0301 DM93 Y478(0.84); Y491(1.31)  LDD0266  [7]
 LDCM0119  HHS-0401 DM93 Y491(0.77); Y478(0.85)  LDD0267  [7]
 LDCM0120  HHS-0701 DM93 Y478(0.85); Y491(1.59)  LDD0268  [7]
 LDCM0107  IAA HeLa C290(0.00); H26(0.00); C64(0.00); C412(0.00)  LDD0221  [13]
 LDCM0126  JWB150 DM93 Y478(5.43)  LDD0288  [6]
 LDCM0127  JWB152 DM93 Y478(3.83)  LDD0289  [6]
 LDCM0130  JWB211 DM93 Y478(2.44)  LDD0292  [6]
 LDCM0022  KB02 42-MG-BA C412(1.40); C64(1.70)  LDD2244  [21]
 LDCM0023  KB03 MDA-MB-231 C412(2.30)  LDD1701  [5]
 LDCM0024  KB05 COLO792 C412(1.62); C64(2.56)  LDD3310  [21]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C412(0.98)  LDD2121  [5]
 LDCM0109  NEM HeLa H57(0.00); H26(0.00); H79(0.00); H94(0.00)  LDD0223  [13]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C412(0.76)  LDD2089  [5]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C412(1.64)  LDD2090  [5]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C64(0.57)  LDD2098  [5]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C64(0.95)  LDD2099  [5]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C64(0.68)  LDD2100  [5]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C64(1.25)  LDD2105  [5]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C64(0.99); C412(0.99)  LDD2107  [5]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C64(0.70)  LDD2109  [5]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C412(0.74)  LDD2120  [5]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C64(0.87); C412(1.59); C133(1.13)  LDD2123  [5]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C133(0.43)  LDD2124  [5]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C64(0.99); C133(1.03)  LDD2125  [5]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C64(1.01); C412(0.97)  LDD2127  [5]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C64(0.92)  LDD2129  [5]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C64(1.51); C412(1.35)  LDD2135  [5]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C412(1.62)  LDD2136  [5]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C64(0.90); C412(1.24); C133(0.85)  LDD2137  [5]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C64(0.36)  LDD2141  [5]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C64(1.04); C412(1.12)  LDD2146  [5]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C412(0.60)  LDD2150  [5]
 LDCM0021  THZ1 HCT 116 C290(0.90)  LDD2173  [8]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
26S proteasome regulatory subunit 4 (PSMC1) AAA ATPase family P62191
26S proteasome regulatory subunit 7 (PSMC2) AAA ATPase family P35998
NADH dehydrogenase flavoprotein 1, mitochondrial (NDUFV1) Complex I 51 kDa subunit family P49821
BTB/POZ domain-containing protein 1 (BTBD1) . Q9H0C5
BTB/POZ domain-containing protein 2 (BTBD2) . Q9BX70
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Wolframin (WFS1) . O76024
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Alpha-globin transcription factor CP2 (TFCP2) Grh/CP2 family Q12800
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cytosolic arginine sensor for mTORC1 subunit 1 (CASTOR1) GATS family Q8WTX7

References

1 2-Ethynylbenzaldehyde-Based, Lysine-Targeting Irreversible Covalent Inhibitors for Protein Kinases and Nonkinases. J Am Chem Soc. 2023 Feb 12. doi: 10.1021/jacs.2c11595. Online ahead of print.
Mass spectrometry data entry: PXD037665
2 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
3 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
4 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
5 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
6 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
7 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
8 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
9 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
10 SP3-Enabled Rapid and High Coverage Chemoproteomic Identification of Cell-State-Dependent Redox-Sensitive Cysteines. Mol Cell Proteomics. 2022 Apr;21(4):100218. doi: 10.1016/j.mcpro.2022.100218. Epub 2022 Feb 25.
Mass spectrometry data entry: PXD029500 , PXD031647
11 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
12 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
13 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
14 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
15 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010
16 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
17 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
18 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
19 Cell-based proteome profiling of potential dasatinib targets by use of affinity-based probes. J Am Chem Soc. 2012 Feb 15;134(6):3001-14. doi: 10.1021/ja208518u. Epub 2012 Feb 1.
20 Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probe. Chem Commun (Camb). 2011 Oct 28;47(40):11306-8. doi: 10.1039/c1cc14824a. Epub 2011 Sep 16.
21 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840