Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0127
Competitor Name
JWB152
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 378.3
Lipid-water partition coefficient (xlogp) 3.5
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C16H9F3N4O2S
IUPAC Name
1-(4-isocyanophenyl)sulfonyl-3-[4-(trifluoromethyl)phenyl]-1,2,4-triazole
Canonical SMILES
[C-]#[N+]C1=CC=C(C=C1)S(=O)(=O)N2C=NC(=N2)C3=CC=C(C=C3)C(F)(F)F
InChI
InChI=1S/C16H9F3N4O2S/c1-20-13-6-8-14(9-7-13)26(24,25)23-10-21-15(22-23)11-2-4-12(5-3-11)16(17,18)19/h2-10H
InChIKey
AWVYLKKUOYMWHG-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
HHS-482
 Probe Info  		50 uM Human melanoma cell lysate (DM93) [1]

Target(s) List of this Competitor

308 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
(3R)-3-hydroxyacyl-CoA dehydrogenase (HSD17B8) LDTP09770 9.10  LDD0289 
1,4-alpha-glucan-branching enzyme (GBE1) LDTP05419 13.31  LDD0289 
14 kDa phosphohistidine phosphatase (PHPT1) LDTP12543 2.81; 2.23  LDD0289 
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) LDTP02356 2.24  LDD0289 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 3.21  LDD0289 
26S proteasome non-ATPase regulatory subunit 3 (PSMD3) LDTP00714 3.59  LDD0289 
26S proteasome non-ATPase regulatory subunit 5 (PSMD5) LDTP06532 3.83  LDD0289 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 1.74  LDD0289 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 1.59  LDD0289 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 20.00; 14.33  LDD0289 
26S proteasome regulatory subunit 7 (PSMC2) LDTP03797 0.42  LDD0289 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 1.45  LDD0289 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 16.39  LDD0289 
5'-3' exoribonuclease 2 (XRN2) LDTP11701 1.67  LDD0289 
6-phosphogluconate dehydrogenase, decarboxylating (PGD) LDTP04499 1.30  LDD0289 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 0.96; 4.23; 2.12 ...  LDD0289 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 2.16  LDD0289 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 2.56  LDD0289 
Acetyl-CoA carboxylase 1 (ACACA) LDTP05742 1.41  LDD0289 
Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) LDTP12463 1.32  LDD0289 
Actin, alpha cardiac muscle 1 (ACTC1) LDTP05069 1.91  LDD0289 
Actin, cytoplasmic 1 (ACTB) LDTP04876 2.30; 1.76; 2.64 ...  LDD0289 
Acylamino-acid-releasing enzyme (APEH) LDTP02693 0.96  LDD0289 
Adenosylhomocysteinase (AHCY) LDTP03242 1.70; 1.76  LDD0289 
Adenylosuccinate synthetase isozyme 2 (ADSS2) LDTP03541 1.00  LDD0289 
ADP-ribose pyrophosphatase, mitochondrial (NUDT9) LDTP11318 1.74  LDD0289 
ADP-ribosylation factor 1 (ARF1) LDTP05192 2.08; 2.44; 0.17  LDD0289 
ADP-ribosylation factor 3 (ARF3) LDTP04907 2.08; 2.44; 0.17  LDD0289 
ADP-ribosylation factor 4 (ARF4) LDTP02942 2.08; 2.44  LDD0289 
ADP-ribosylation factor 5 (ARF5) LDTP05193 2.08; 2.44  LDD0289 
ADP-sugar pyrophosphatase (NUDT5) LDTP13462 2.41  LDD0289 
Aflatoxin B1 aldehyde reductase member 2 (AKR7A2) LDTP00776 1.44; 1.16; 2.53 ...  LDD0289 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 2.14; 1.16  LDD0289 
Alcohol dehydrogenase class-3 (ADH5) LDTP02587 2.11; 0.60; 1.70  LDD0289 
Aldo-keto reductase family 1 member A1 (AKR1A1) LDTP02729 1.00  LDD0289 
Alpha-aminoadipic semialdehyde synthase, mitochondrial (AASS) LDTP13186 0.54; 1.14; 2.53  LDD0289 
Alpha-enolase (ENO1) LDTP02159 2.43; 2.04; 4.54 ...  LDD0289 
Amidophosphoribosyltransferase (PPAT) LDTP05480 1.64  LDD0289 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 0.07; 1.45  LDD0289 
Asparagine synthetase [glutamine-hydrolyzing] (ASNS) LDTP02264 2.61; 1.55  LDD0289 
Asparagine--tRNA ligase, cytoplasmic (NARS1) LDTP00866 2.43; 2.20; 0.09 ...  LDD0289 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 11.92; 1.60; 1.23  LDD0289 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 6.95; 2.11; 2.74  LDD0289 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 1.81; 4.24; 3.65  LDD0289 
ATP-citrate synthase (ACLY) LDTP04561 2.05; 2.50; 2.93 ...  LDD0289 
ATP-dependent 6-phosphofructokinase, liver type (PFKL) LDTP02925 2.00  LDD0289 
ATP-dependent 6-phosphofructokinase, muscle type (PFKM) LDTP02261 2.59  LDD0289 
ATP-dependent RNA helicase A (DHX9) LDTP05550 1.33; 2.17  LDD0289 
ATP-dependent RNA helicase DDX1 (DDX1) LDTP09766 2.18  LDD0289 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 3.16  LDD0289 
ATPase MORC2 (MORC2) LDTP14308 15.86  LDD0289 
Aurora kinase B (AURKB) LDTP10346 0.47  LDD0289 
Bifunctional coenzyme A synthase (COASY) LDTP05736 2.47  LDD0289 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 2.11  LDD0289 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 4.83  LDD0289 
Biliverdin reductase A (BLVRA) LDTP04552 1.73  LDD0289 
Biotinidase (BTD) LDTP04030 3.51  LDD0289 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 3.96; 1.14; 1.90 ...  LDD0289 
Calcyclin-binding protein (CACYBP) LDTP12163 2.29; 3.24; 2.83  LDD0289 
Carbonyl reductase [NADPH] 1 (CBR1) LDTP02831 4.95  LDD0289 
Carbonyl reductase [NADPH] 3 (CBR3) LDTP01321 1.86  LDD0289 
Casein kinase II subunit beta (CSNK2B) LDTP05067 1.32  LDD0289 
Catalase (CAT) LDTP02001 0.98  LDD0289 
Cathepsin B (CTSB) LDTP02223 1.64; 1.67; 1.66 ...  LDD0289 
Cathepsin D (CTSD) LDTP02198 1.56; 1.67  LDD0289 
Cathepsin Z (CTSZ) LDTP13147 2.17; 2.70; 4.43 ...  LDD0289 
Citrate synthase, mitochondrial (CS) LDTP01205 2.57; 1.75  LDD0289 
Cleavage and polyadenylation specificity factor subunit 5 (NUDT21) LDTP00873 2.41  LDD0289 
CTP synthase 1 (CTPS1) LDTP02922 1.67; 3.42; 1.87  LDD0289 
Cyclin-dependent kinase 1 (CDK1) LDTP02149 1.55; 5.11; 1.74 ...  LDD0289 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 1.55; 1.74; 9.72  LDD0289 
Cystathionine gamma-lyase (CTH) LDTP03656 2.34  LDD0289 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 1.16  LDD0289 
Cytochrome c oxidase assembly factor 7 (COA7) LDTP10137 1.77  LDD0289 
Cytoglobin (CYGB) LDTP09656 2.34; 3.29  LDD0289 
Cytosol aminopeptidase (LAP3) LDTP03455 1.87  LDD0289 
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 12.85; 2.19  LDD0289 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 5.12  LDD0289 
Dehydrogenase/reductase SDR family member 11 (DHRS11) LDTP07678 1.13  LDD0289 
Dihydropteridine reductase (QDPR) LDTP02342 0.55  LDD0289 
Dihydropyrimidinase-related protein 3 (DPYSL3) LDTP06079 3.29  LDD0289 
Dipeptidyl peptidase 3 (DPP3) LDTP12803 1.26  LDD0289 
DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 2.39  LDD0289 
DNA replication licensing factor MCM2 (MCM2) LDTP04286 1.62  LDD0289 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 4.67  LDD0289 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 2.36  LDD0289 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 0.09  LDD0289 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 2.58  LDD0289 
DNA replication licensing factor MCM7 (MCM7) LDTP03682 0.92  LDD0289 
Dual specificity protein phosphatase 23 (DUSP23) LDTP11289 1.45  LDD0289 
Dual specificity protein phosphatase 3 (DUSP3) LDTP04415 2.40  LDD0289 
Dynamin-1-like protein (DNM1L) LDTP00273 0.19  LDD0289 
E3 ubiquitin-protein ligase ARIH2 (ARIH2) LDTP01575 2.45  LDD0289 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 1.48  LDD0289 
EH domain-containing protein 4 (EHD4) LDTP11788 1.64  LDD0289 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 2.71; 1.61; 1.84 ...  LDD0289 
Elongation factor 2 (EEF2) LDTP02672 3.15; 0.95; 2.48 ...  LDD0289 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 1.96; 1.67; 1.87 ...  LDD0289 
Endoplasmic reticulum chaperone BiP (HSPA5) LDTP02534 20.00; 2.90; 4.71 ...  LDD0289 
Enoyl-CoA hydratase, mitochondrial (ECHS1) LDTP03518 2.21  LDD0289 
ERO1-like protein alpha (ERO1A) LDTP10386 3.10  LDD0289 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 4.73; 1.91; 2.27 ...  LDD0289 
Eukaryotic initiation factor 4A-II (EIF4A2) LDTP06089 3.07; 2.16; 1.15  LDD0294 
Eukaryotic initiation factor 4A-III (EIF4A3) LDTP03861 1.81  LDD0289 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 2.65  LDD0289 
Exosome complex exonuclease RRP44 (DIS3) LDTP13887 2.09  LDD0289 
Farnesyl pyrophosphate synthase (FDPS) LDTP02721 3.00  LDD0289 
Fatty acid CoA ligase Acsl3 (ACSL3) LDTP01634 8.80; 1.45  LDD0289 
Fatty acid synthase (FASN) LDTP04243 2.35; 1.24; 1.79 ...  LDD0289 
Flap endonuclease 1 (FEN1) LDTP03872 1.50  LDD0289 
Fructose-2,6-bisphosphatase TIGAR (TIGAR) LDTP12405 1.77  LDD0289 
Fructose-bisphosphate aldolase A (ALDOA) LDTP02008 2.38; 4.67; 3.07 ...  LDD0289 
Fumarate hydratase, mitochondrial (FH) LDTP02235 1.24  LDD0289 
Fumarylacetoacetase (FAH) LDTP02868 6.96  LDD0289 
Galactokinase (GALK1) LDTP04424 1.51  LDD0289 
Gamma-enolase (ENO2) LDTP02328 1.71; 2.69  LDD0289 
GDP-mannose 4,6 dehydratase (GMDS) LDTP00999 1.76  LDD0289 
Geranylgeranyl transferase type-2 subunit beta (RABGGTB) LDTP04569 2.45  LDD0289 
Glucosamine-6-phosphate isomerase 1 (GNPDA1) LDTP04113 3.12  LDD0289 
Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 1.67; 1.75  LDD0289 
Glucose-6-phosphate isomerase (GPI) LDTP02162 1.40; 4.07; 1.96  LDD0289 
Glutaminase kidney isoform, mitochondrial (GLS) LDTP01465 0.70  LDD0289 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) LDTP05481 1.50; 4.11  LDD0289 
Glutaredoxin-1 (GLRX) LDTP03786 1.81  LDD0289 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 5.93; 5.32  LDD0289 
Glutathione S-transferase A4 (GSTA4) LDTP00575 3.77  LDD0289 
Glutathione S-transferase kappa 1 (GSTK1) LDTP13900 2.33  LDD0289 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 1.60  LDD0289 
Glutathione S-transferase P (GSTP1) LDTP02333 1.41; 1.17; 1.04 ...  LDD0289 
Glutathione synthetase (GSS) LDTP04200 1.84; 0.76  LDD0289 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 2.56; 1.23; 1.37 ...  LDD0289 
Glycine--tRNA ligase (GARS1) LDTP03946 2.23; 3.04; 6.54 ...  LDD0289 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 1.98; 1.48; 2.13 ...  LDD0289 
Glycogen phosphorylase, liver form (PYGL) LDTP02161 3.64  LDD0289 
Glycogen synthase kinase-3 alpha (GSK3A) LDTP04318 6.86  LDD0289 
Glycogen synthase kinase-3 beta (GSK3B) LDTP04319 6.86  LDD0289 
GTP-binding nuclear protein Ran (RAN) LDTP05007 2.07; 2.56; 1.06 ...  LDD0289 
HBS1-like protein (HBS1L) LDTP14019 1.80  LDD0289 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 2.58; 2.15; 2.10 ...  LDD0289 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 1.23; 2.38; 3.13 ...  LDD0289 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 1.82  LDD0289 
Histone deacetylase 1 (HDAC1) LDTP05918 2.15  LDD0289 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 1.53  LDD0289 
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL) LDTP03794 2.70  LDD0289 
Inorganic pyrophosphatase (PPA1) LDTP14854 1.37; 2.38; 0.83 ...  LDD0289 
Inorganic pyrophosphatase 2, mitochondrial (PPA2) LDTP11842 1.18  LDD0289 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 1.22; 1.58; 1.28 ...  LDD0289 
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) LDTP11700 1.74  LDD0289 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 1.56; 2.96; 1.18 ...  LDD0289 
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A) LDTP04345 1.42  LDD0289 
Isoleucine--tRNA ligase, cytoplasmic (IARS1) LDTP03947 2.15  LDD0289 
Kynurenine--oxoglutarate transaminase 3 (KYAT3) LDTP07763 0.36; 0.87  LDD0289 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 1.98; 2.16; 3.27 ...  LDD0289 
L-lactate dehydrogenase B chain (LDHB) LDTP02179 1.86; 1.47; 2.20 ...  LDD0289 
L-xylulose reductase (DCXR) LDTP08082 3.66  LDD0289 
Lactoylglutathione lyase (GLO1) LDTP05434 3.06  LDD0289 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 1.28  LDD0289 
Low molecular weight phosphotyrosine protein phosphatase (ACP1) LDTP03289 3.04; 4.43; 5.54  LDD0289 
Lymphokine-activated killer T-cell-originated protein kinase (PBK) LDTP10500 1.99; 5.62; 1.82  LDD0289 
Lysosomal protective protein (CTSA) LDTP02505 8.01  LDD0289 
Macrophage migration inhibitory factor (MIF) LDTP02713 1.65; 2.83; 1.52 ...  LDD0289 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 1.92; 2.59  LDD0289 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 1.02; 0.97; 1.57 ...  LDD0289 
Mannose-1-phosphate guanyltransferase beta (GMPPB) LDTP14141 1.71  LDD0289 
MAP kinase-activated protein kinase 3 (MAPKAPK3) LDTP06589 0.83; 0.95  LDD0289 
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) LDTP02565 1.06; 1.86; 0.32 ...  LDD0289 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 1.74  LDD0289 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 5.09  LDD0289 
Methylmalonyl-CoA mutase, mitochondrial (MMUT) LDTP03150 1.13  LDD0289 
Methylthioribulose-1-phosphate dehydratase (APIP) LDTP10368 0.83  LDD0289 
Mitochondrial-processing peptidase subunit beta (PMPCB) LDTP01220 4.81  LDD0289 
Mitogen-activated protein kinase 1 (MAPK1) LDTP03445 2.26  LDD0289 
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) LDTP01005 2.30; 1.70  LDD0289 
Myosin-10 (MYH10) LDTP03765 1.25; 4.01; 1.96 ...  LDD0289 
Myosin-9 (MYH9) LDTP03764 1.51; 3.46; 1.50 ...  LDD0289 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 1.49  LDD0289 
NAD(P)H dehydrogenase [quinone] 1 (NQO1) LDTP02798 15.12; 2.95; 4.05  LDD0289 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 1.67  LDD0289 
NEDD8-activating enzyme E1 regulatory subunit (NAE1) LDTP05925 1.75  LDD0289 
NEDD8-conjugating enzyme Ubc12 (UBE2M) LDTP04898 1.55  LDD0289 
Neutral alpha-glucosidase AB (GANAB) LDTP06192 1.93; 2.74  LDD0289 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 3.68  LDD0289 
Nucleoside diphosphate kinase B (NME2) LDTP03169 1.99  LDD0289 
Omega-amidase NIT2 (NIT2) LDTP12428 0.58; 2.36; 1.61 ...  LDD0289 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 1.87; 2.57; 3.19  LDD0289 
Palmitoyltransferase ZDHHC17 (ZDHHC17) LDTP08456 1.01  LDD0289 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 2.82; 2.07  LDD0289 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 2.03  LDD0289 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 2.21; 1.34  LDD0289 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 0.21; 4.53; 2.14  LDD0289 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) LDTP05912 2.24  LDD0289 
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3) LDTP11823 10.25  LDD0289 
Peroxiredoxin-1 (PRDX1) LDTP05503 2.64; 1.61; 1.93  LDD0289 
Peroxiredoxin-4 (PRDX4) LDTP05773 3.00; 2.02  LDD0289 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 1.56  LDD0289 
Phosphatidylinositide phosphatase SAC2 (INPP5F) LDTP13867 1.46  LDD0289 
Phosphoglucomutase-1 (PGM1) LDTP03818 5.86  LDD0289 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 3.10; 2.00; 2.32 ...  LDD0289 
Phosphoglycerate mutase 1 (PGAM1) LDTP02963 2.22; 4.58; 2.54 ...  LDD0289 
Phosphoserine aminotransferase (PSAT1) LDTP14198 2.31; 1.78; 0.69 ...  LDD0289 
Poly(A) polymerase alpha (PAPOLA) LDTP04394 1.68  LDD0289 
Presequence protease, mitochondrial (PITRM1) LDTP07003 1.12  LDD0289 
Probable 18S rRNA (guanine-N(7))-methyltransferase (BUD23) LDTP00845 1.97  LDD0289 
Probable aminopeptidase NPEPL1 (NPEPL1) LDTP09126 1.66  LDD0289 
Probable E3 ubiquitin-protein ligase IRF2BPL (IRF2BPL) LDTP11759 2.06; 0.92  LDD0289 
Prolyl endopeptidase (PREP) LDTP04163 2.44  LDD0289 
Prostaglandin reductase 1 (PTGR1) LDTP06227 2.19; 2.38; 2.62  LDD0289 
Prostaglandin reductase 2 (PTGR2) LDTP08979 20.00; 7.93; 20.00  LDD0289 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 1.87; 3.63  LDD0289 
Proteasome subunit alpha type-2 (PSMA2) LDTP03331 2.08; 1.90; 1.95  LDD0289 
Proteasome subunit alpha type-3 (PSMA3) LDTP03332 1.45  LDD0289 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 1.73; 1.58; 1.68 ...  LDD0289 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 1.54; 1.82; 1.54 ...  LDD0289 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 6.90; 8.35  LDD0289 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 0.81; 1.39  LDD0289 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 1.58  LDD0289 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 3.54; 1.60  LDD0289 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 1.70; 1.16  LDD0289 
Protein arginine N-methyltransferase 5 (PRMT5) LDTP00418 0.74  LDD0289 
Protein disulfide-isomerase (P4HB) LDTP02188 5.67; 1.96; 3.79 ...  LDD0289 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 2.04; 3.12; 3.06 ...  LDD0289 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 3.48; 3.98; 8.10  LDD0289 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 1.79  LDD0289 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 1.81  LDD0289 
Protein kinase C delta type (PRKCD) LDTP05461 2.69  LDD0289 
Protein phosphatase 1G (PPM1G) LDTP00616 20.00  LDD0289 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 1.12  LDD0289 
Putative elongation factor 1-alpha-like 3 (EEF1A1P5) LDTP15029 2.71; 1.61; 1.84 ...  LDD0289 
Pyridoxine-5'-phosphate oxidase (PNPO) LDTP12691 1.72  LDD0289 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 1.14; 3.45  LDD0289 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 2.11; 3.73; 1.71 ...  LDD0289 
Pyruvate kinase PKM (PKM) LDTP02733 1.70; 2.09; 1.87 ...  LDD0289 
Queuine tRNA-ribosyltransferase catalytic subunit 1 (QTRT1) LDTP11400 1.18  LDD0289 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 2.88; 1.31  LDD0289 
RAC-gamma serine/threonine-protein kinase (AKT3) LDTP13799 1.95; 1.31  LDD0289 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 2.05; 2.00  LDD0289 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 1.56; 1.16  LDD0289 
Ribonucleoside-diphosphate reductase large subunit (RRM1) LDTP03259 2.52  LDD0289 
RING finger and CHY zinc finger domain-containing protein 1 (RCHY1) LDTP10686 1.89  LDD0289 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 0.47  LDD0289 
RNA demethylase ALKBH5 (ALKBH5) LDTP07547 3.38  LDD0289 
RNA-splicing ligase RtcB homolog (RTCB) LDTP13992 4.22  LDD0289 
RuvB-like 1 (RUVBL1) LDTP13816 1.67  LDD0289 
S-adenosylmethionine synthase isoform type-2 (MAT2A) LDTP03577 0.67; 1.09  LDD0289 
S-formylglutathione hydrolase (ESD) LDTP02521 2.39; 1.15  LDD0289 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 2.64  LDD0289 
Sepiapterin reductase (SPR) LDTP03730 2.03  LDD0289 
Septin-2 (SEPTIN2) LDTP06279 0.49; 2.15  LDD0289 
Septin-7 (SEPTIN7) LDTP06513 1.43; 1.91  LDD0289 
Septin-9 (SEPTIN9) LDTP13272 1.75; 1.59; 1.53  LDD0289 
Serine hydroxymethyltransferase, cytosolic (SHMT1) LDTP03688 3.15  LDD0289 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 0.85  LDD0289 
Serine/threonine-protein kinase PAK 2 (PAK2) LDTP05776 2.10  LDD0289 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 2.08  LDD0289 
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) LDTP05064 1.49  LDD0289 
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB) LDTP04998 1.45  LDD0289 
Serine/threonine-protein phosphatase 4 catalytic subunit (PPP4C) LDTP04870 1.49  LDD0289 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 2.28  LDD0289 
Serine/threonine-protein phosphatase 6 catalytic subunit (PPP6C) LDTP00333 3.91  LDD0289 
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) LDTP04959 2.02; 2.26  LDD0289 
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) LDTP04960 2.02; 2.35  LDD0289 
Sialic acid synthase (NANS) LDTP12473 2.08; 1.72; 1.90  LDD0289 
Spermidine synthase (SRM) LDTP03008 1.83  LDD0289 
Spliceosome RNA helicase DDX39B (DDX39B) LDTP05991 1.23  LDD0289 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 1.77; 1.52  LDD0289 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 1.87  LDD0289 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 1.34  LDD0289 
SUMO-activating enzyme subunit 2 (UBA2) LDTP13156 1.75; 2.05  LDD0289 
SUMO-conjugating enzyme UBC9 (UBE2I) LDTP05062 6.14  LDD0289 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 0.90; 3.12; 2.74  LDD0289 
Thimet oligopeptidase (THOP1) LDTP04542 1.74  LDD0289 
Thioredoxin domain-containing protein 12 (TXNDC12) LDTP01707 1.67  LDD0289 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 1.76; 1.86; 1.80 ...  LDD0289 
Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) LDTP03515 1.81  LDD0289 
Threonine--tRNA ligase 1, cytoplasmic (TARS1) LDTP03365 1.29; 2.55; 1.71 ...  LDD0289 
Thymidylate kinase (DTYMK) LDTP03258 1.45; 2.73  LDD0289 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 1.62; 2.23; 1.77 ...  LDD0289 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 2.77  LDD0289 
Transketolase (TKT) LDTP03487 1.62; 1.10; 1.84 ...  LDD0289 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 1.84  LDD0289 
Triosephosphate isomerase (TPI1) LDTP04851 0.32; 11.04; 1.61  LDD0289 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 3.51  LDD0289 
Tryptophan--tRNA ligase, cytoplasmic (WARS1) LDTP03222 1.87; 3.19; 1.30 ...  LDD0289 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 1.74; 1.71; 1.62 ...  LDD0289 
Tubulin alpha-1B chain (TUBA1B) LDTP05074 1.74; 1.71; 1.62 ...  LDD0289 
Tubulin alpha-1C chain (TUBA1C) LDTP11074 1.55  LDD0289 
Tubulin--tyrosine ligase-like protein 12 (TTLL12) LDTP06067 0.79; 0.16  LDD0289 
Tyrosine--tRNA ligase, cytoplasmic (YARS1) LDTP04617 1.34; 1.89  LDD0289 
Tyrosine-protein kinase CSK (CSK) LDTP03944 1.98  LDD0289 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 2.94  LDD0289 
Ubiquitin carboxyl-terminal hydrolase 14 (USP14) LDTP04618 4.19; 3.18  LDD0289 
Ubiquitin carboxyl-terminal hydrolase 39 (USP39) LDTP06903 1.46  LDD0289 
Ubiquitin carboxyl-terminal hydrolase 4 (USP4) LDTP05749 2.41  LDD0289 
Ubiquitin-conjugating enzyme E2 N (UBE2N) LDTP04900 3.32; 6.75; 2.87  LDD0289 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 4.19; 2.58; 2.24 ...  LDD0289 
UDP-glucose 4-epimerase (GALE) LDTP06111 3.00  LDD0289 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 1.63; 1.28; 1.75 ...  LDD0289 
UMP-CMP kinase (CMPK1) LDTP03519 0.89  LDD0289 
Unconventional myosin-Ie (MYO1E) LDTP05708 4.97  LDD0289 
Uridine 5'-monophosphate synthase (UMPS) LDTP02548 1.95  LDD0289 
Uridine phosphorylase 1 (UPP1) LDTP06643 1.48; 5.32; 1.79 ...  LDD0289 
Uroporphyrinogen decarboxylase (UROD) LDTP02135 1.79; 1.03  LDD0289 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 1.90; 2.66; 2.14  LDD0289 
V-type proton ATPase subunit E 2 (ATP6V1E2) LDTP15684 1.77  LDD0289 
Valine--tRNA ligase (VARS1) LDTP03366 2.87; 1.17  LDD0289 
WD repeat-containing protein 82 (WDR82) LDTP07715 2.88  LDD0289 
Xaa-Pro aminopeptidase 1 (XPNPEP1) LDTP12444 4.34; 1.87  LDD0289 
Xaa-Pro dipeptidase (PEPD) LDTP02639 4.02  LDD0289 
------------------------------------------------------------------------------------
⏷ Show the Full List of 308 Enzyme
40 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein epsilon (YWHAE) LDTP04969 1.42; 2.06; 2.08 ...  LDD0289 
14-3-3 protein gamma (YWHAG) LDTP04953 2.89; 1.31  LDD0289 
14-3-3 protein theta (YWHAQ) LDTP03385 3.09  LDD0289 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 1.90; 2.12; 2.81 ...  LDD0289 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 1.65; 1.70  LDD0289 
Alpha-synuclein (SNCA) LDTP03848 3.88  LDD0289 
Annexin A2 (ANXA2) LDTP02199 1.37; 2.39; 0.34 ...  LDD0289 
Annexin A5 (ANXA5) LDTP02307 5.13; 2.67; 2.36 ...  LDD0289 
Annexin A6 (ANXA6) LDTP02247 4.32; 1.97  LDD0289 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 1.66  LDD0289 
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 1.42; 1.80  LDD0289 
Calreticulin (CALR) LDTP03402 2.14; 2.65; 2.83 ...  LDD0289 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 2.36; 1.54; 3.02 ...  LDD0289 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 3.00; 1.40; 3.07 ...  LDD0289 
Clathrin heavy chain 1 (CLTC) LDTP05252 1.16; 2.04  LDD0289 
Copine-3 (CPNE3) LDTP01133 2.10; 2.03  LDD0289 
Cystatin-B (CSTB) LDTP02009 2.34; 3.04; 1.81  LDD0289 
Dihydropyrimidinase-related protein 2 (DPYSL2) LDTP06554 2.16; 3.29; 3.12 ...  LDD0289 
Eukaryotic translation initiation factor 5A-1 (EIF5A) LDTP05056 8.88; 3.03  LDD0289 
Exportin-1 (XPO1) LDTP00501 1.81; 2.61  LDD0289 
Exportin-2 (CSE1L) LDTP04662 2.94  LDD0289 
Filamin-A (FLNA) LDTP03107 1.99; 2.15  LDD0289 
Galectin-3 (LGALS3) LDTP02929 2.16  LDD0289 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 2.11; 1.23; 2.50 ...  LDD0289 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 1.68  LDD0289 
Importin subunit beta-1 (KPNB1) LDTP06242 1.68  LDD0289 
mRNA export factor RAE1 (RAE1) LDTP05122 1.97  LDD0289 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 1.69; 1.28  LDD0289 
Sorting nexin-2 (SNX2) LDTP01043 0.67  LDD0289 
T-complex protein 1 subunit delta (CCT4) LDTP04391 1.62; 1.85; 1.63 ...  LDD0289 
Talin-1 (TLN1) LDTP14031 1.33; 2.15; 0.79 ...  LDD0289 
Thioredoxin domain-containing protein 17 (TXNDC17) LDTP11103 1.43; 1.00; 2.50  LDD0289 
Transferrin receptor protein 1 (TFRC) LDTP01969 4.23  LDD0289 
Ubiquilin-4 (UBQLN4) LDTP12533 2.04  LDD0289 
V-type proton ATPase subunit B, brain isoform (ATP6V1B2) LDTP03104 3.99; 1.87  LDD0289 
V-type proton ATPase subunit C 1 (ATP6V1C1) LDTP03105 2.68  LDD0289 
V-type proton ATPase subunit E 1 (ATP6V1E1) LDTP03811 1.77  LDD0289 
V-type proton ATPase subunit G 1 (ATP6V1G1) LDTP01185 1.59  LDD0289 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 1.86  LDD0289 
Voltage-gated potassium channel subunit beta-2 (KCNAB2) LDTP05817 2.54  LDD0289 
------------------------------------------------------------------------------------
⏷ Show the Full List of 40 Transporter and channel
8 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
Forkhead box protein K1 (FOXK1) LDTP05201 2.01  LDD0289 
High mobility group protein B1 (HMGB1) LDTP02343 1.47; 1.90; 1.52 ...  LDD0289 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 2.11  LDD0289 
Nascent polypeptide-associated complex subunit alpha, muscle-specific form (NACA) LDTP14411 0.26  LDD0289 
Signal transducer and activator of transcription 5A (STAT5A) LDTP03971 2.96  LDD0289 
Transcription factor SOX-10 (SOX10) LDTP04752 1.97; 1.27  LDD0289 
Transcription factor SOX-9 (SOX9) LDTP04179 1.97  LDD0289 
Y-box-binding protein 1 (YBX1) LDTP05065 2.74; 3.19; 1.59  LDD0289 
------------------------------------------------------------------------------------
⏷ Show the Full List of 8 Transcription factor
285 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
10 kDa heat shock protein, mitochondrial (HSPE1) LDTP04931 7.13  LDD0289 
14-3-3 protein beta/alpha (YWHAB) LDTP03617 2.18; 3.04  LDD0289 
14-3-3 protein eta (YWHAH) LDTP05442 0.88  LDD0289 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 2.21  LDD0289 
55 kDa erythrocyte membrane protein (MPP1) LDTP05233 1.44  LDD0289 
Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) LDTP03871 2.51  LDD0289 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 2.03  LDD0289 
Actin nucleation-promoting factor WASL (WASL) LDTP00263 3.32  LDD0289 
Actin-related protein 3 (ACTR3) LDTP04902 2.12; 2.11; 1.19 ...  LDD0289 
Adapter molecule crk (CRK) LDTP04091 2.97; 1.33; 1.86  LDD0289 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 1.30; 2.23; 2.85  LDD0289 
AH receptor-interacting protein (AIP) LDTP00202 1.82  LDD0289 
Alpha-actinin-1 (ACTN1) LDTP02631 1.34; 1.35; 5.19  LDD0289 
Alpha-centractin (ACTR1A) LDTP04904 1.96  LDD0289 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 1.71  LDD0289 
Anamorsin (CIAPIN1) LDTP07385 0.97  LDD0289 
Ankyrin repeat and MYND domain-containing protein 2 (ANKMY2) LDTP17620 2.67  LDD0289 
Ankyrin repeat domain-containing protein 39 (ANKRD39) LDTP19320 10.90  LDD0289 
Annexin A3 (ANXA3) LDTP02620 1.43  LDD0289 
Annexin A7 (ANXA7) LDTP03030 1.50  LDD0289 
Apoptosis inhibitor 5 (API5) LDTP11575 2.15  LDD0289 
Beta-parvin (PARVB) LDTP12184 0.34  LDD0289 
Bifunctional purine biosynthesis protein ATIC (ATIC) LDTP03612 4.01; 1.86; 1.58 ...  LDD0289 
Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (ARFGEF2) LDTP14237 3.94  LDD0289 
C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9) LDTP00934 4.61; 2.06  LDD0289 
Calpain small subunit 1 (CAPNS1) LDTP02047 1.99  LDD0289 
Calponin-3 (CNN3) LDTP06383 1.98; 1.88; 2.32 ...  LDD0289 
Calumenin (CALU) LDTP00887 1.69; 1.62; 2.02 ...  LDD0289 
cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) LDTP02697 1.30  LDD0289 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 2.00; 2.12; 2.34 ...  LDD0289 
Coatomer subunit alpha (COPA) LDTP04571 2.19  LDD0289 
Coatomer subunit beta (COPB1) LDTP04570 2.17  LDD0289 
Coatomer subunit gamma-1 (COPG1) LDTP14216 2.38  LDD0289 
Cofilin-1 (CFL1) LDTP03244 1.58; 2.46; 1.95 ...  LDD0289 
Cofilin-2 (CFL2) LDTP13827 0.71; 0.73  LDD0294 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 2.25  LDD0289 
Condensin complex subunit 2 (NCAPH) LDTP06268 1.94  LDD0289 
Copper transport protein ATOX1 (ATOX1) LDTP00229 2.13  LDD0289 
Coronin-1B (CORO1B) LDTP11101 3.40  LDD0289 
Coronin-1C (CORO1C) LDTP13580 2.13  LDD0289 
Crk-like protein (CRKL) LDTP04092 2.32; 1.55  LDD0289 
Cysteine and glycine-rich protein 1 (CSRP1) LDTP03106 3.77; 1.45; 1.73  LDD0289 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 2.78; 0.83; 1.78 ...  LDD0289 
Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2) LDTP05855 3.81  LDD0289 
Cytoplasmic FMR1-interacting protein 1 (CYFIP1) LDTP07958 2.02  LDD0289 
Cytotoxic granule associated RNA binding protein TIA1 (TIA1) LDTP03598 2.24  LDD0289 
Destrin (DSTN) LDTP04887 1.25; 0.65  LDD0289 
DnaJ homolog subfamily A member 2 (DNAJA2) LDTP01073 1.73  LDD0289 
DnaJ homolog subfamily B member 1 (DNAJB1) LDTP03325 2.36  LDD0289 
DnaJ homolog subfamily C member 3 (DNAJC3) LDTP05789 2.72  LDD0289 
DnaJ homolog subfamily C member 8 (DNAJC8) LDTP01361 1.91  LDD0289 
Drebrin-like protein (DBNL) LDTP13399 1.92; 1.95; 1.93  LDD0289 
Dynactin subunit 1 (DCTN1) LDTP06082 0.83  LDD0289 
Dynactin subunit 2 (DCTN2) LDTP05922 1.36  LDD0289 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 2.84  LDD0289 
Dynein light chain 2, cytoplasmic (DYNLL2) LDTP10308 2.59  LDD0289 
Elongation factor 1-beta (EEF1B2) LDTP03283 2.14; 2.18; 2.46 ...  LDD0289 
Elongation factor 1-delta (EEF1D) LDTP03499 1.96; 2.15; 1.22 ...  LDD0289 
Elongation factor 1-gamma (EEF1G) LDTP03367 1.60; 2.11; 3.75  LDD0289 
Endoplasmic reticulum resident protein 29 (ERP29) LDTP03509 2.17; 1.51; 8.74  LDD0289 
Endoplasmin (HSP90B1) LDTP02734 4.27; 3.88; 1.82 ...  LDD0289 
Enhancer of mRNA-decapping protein 3 (EDC3) LDTP10299 2.01  LDD0289 
Epidermal growth factor receptor substrate 15-like 1 (EPS15L1) LDTP13097 2.86  LDD0289 
Eukaryotic translation initiation factor 1 (EIF1) LDTP03953 2.69  LDD0289 
Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX) LDTP04129 1.33  LDD0289 
Eukaryotic translation initiation factor 1b (EIF1B) LDTP16815 2.69  LDD0289 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 1.94  LDD0289 
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) LDTP03027 1.60  LDD0289 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 2.77  LDD0289 
Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 1.84  LDD0289 
Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 1.50  LDD0289 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 2.49  LDD0289 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 1.70; 2.42  LDD0289 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 1.91  LDD0289 
Eukaryotic translation initiation factor 4H (EIF4H) LDTP06301 2.22  LDD0289 
F-actin-uncapping protein LRRC16A (CARMIL1) LDTP07261 2.26  LDD0289 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 7.16; 1.50  LDD0289 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 2.13; 2.12; 1.58 ...  LDD0289 
Gelsolin (GSN) LDTP02145 5.96; 1.99; 2.74 ...  LDD0289 
General transcription factor IIF subunit 2 (GTF2F2) LDTP02703 1.54; 1.91  LDD0289 
General vesicular transport factor p115 (USO1) LDTP01048 2.44  LDD0289 
Growth factor receptor-bound protein 2 (GRB2) LDTP05035 2.43  LDD0289 
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPVD1) LDTP06255 2.56  LDD0289 
Heat shock 70 kDa protein 1A (HSPA1A) LDTP02434 2.62; 2.56; 2.13 ...  LDD0289 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 1.68; 1.77; 0.87 ...  LDD0289 
Heat shock 70 kDa protein 4L (HSPA4L) LDTP14545 8.14  LDD0289 
Heat shock protein 105 kDa (HSPH1) LDTP09811 1.74; 2.72  LDD0289 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 2.65  LDD0289 
Heat shock protein beta-1 (HSPB1) LDTP02053 1.73; 1.45; 1.44 ...  LDD0289 
Heme-binding protein 1 (HEBP1) LDTP16078 4.45; 0.19  LDD0289 
Hepatoma-derived growth factor (HDGF) LDTP04483 0.64  LDD0289 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 1.71; 1.54  LDD0289 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 2.30; 1.97; 1.67 ...  LDD0289 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 2.00; 2.02; 2.42  LDD0289 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 2.18  LDD0289 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 1.84; 1.61; 1.65 ...  LDD0289 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 1.55; 2.03; 2.00 ...  LDD0289 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 1.39; 1.87; 1.89 ...  LDD0289 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 1.99  LDD0289 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 1.99  LDD0289 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 1.75; 1.74; 2.14 ...  LDD0289 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 2.04; 2.25; 2.13 ...  LDD0289 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 2.05  LDD0289 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 2.14; 1.87; 2.71 ...  LDD0289 
Histone H2B type 1-D (H2BC5) LDTP04822 3.20; 3.12; 2.74  LDD0289 
Histone H2B type 1-L (H2BC13) LDTP11001 2.74  LDD0289 
Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) LDTP05004 3.32; 2.09  LDD0289 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 1.67; 1.85  LDD0289 
Hsc70-interacting protein (ST13) LDTP04367 9.67; 1.31; 1.78  LDD0289 
Influenza virus NS1A-binding protein (IVNS1ABP) LDTP14309 1.87  LDD0289 
Integrator complex subunit 10 (INTS10) LDTP16111 1.91  LDD0289 
IST1 homolog (IST1) LDTP04593 2.27  LDD0289 
Kelch-like protein 36 (KLHL36) LDTP08871 0.29  LDD0289 
Kinesin light chain 1 (KLC1) LDTP05533 2.15; 1.29  LDD0289 
Kinesin light chain 2 (KLC2) LDTP11695 2.15; 1.29  LDD0289 
Laminin subunit beta-2 (LAMB2) LDTP04691 1.55  LDD0289 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 2.35  LDD0289 
Large ribosomal subunit protein eL21 (RPL21) LDTP04107 1.24; 0.81; 1.91  LDD0289 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 0.64; 1.72  LDD0289 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 1.08; 6.47  LDD0289 
Large ribosomal subunit protein eL29 (RPL29) LDTP04140 2.21  LDD0289 
Large ribosomal subunit protein eL31 (RPL31) LDTP05023 5.25; 2.78  LDD0289 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 6.63; 1.36  LDD0289 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 1.29  LDD0289 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 1.95  LDD0289 
Large ribosomal subunit protein eL37 (RPL37) LDTP04943 2.25  LDD0289 
Large ribosomal subunit protein eL43 (RPL37A) LDTP04926 1.92  LDD0289 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 3.12; 1.33  LDD0289 
Large ribosomal subunit protein uL13 (RPL13A) LDTP03899 3.06; 1.66; 1.83  LDD0289 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 2.25  LDD0289 
Large ribosomal subunit protein uL15 (RPL27A) LDTP04105 2.27  LDD0289 
Large ribosomal subunit protein uL16 (RPL10) LDTP03395 1.69  LDD0289 
Large ribosomal subunit protein uL18 (RPL5) LDTP04106 2.05  LDD0289 
Large ribosomal subunit protein uL2 (RPL8) LDTP05027 1.76  LDD0289 
Large ribosomal subunit protein uL22 (RPL17) LDTP02961 1.76  LDD0289 
Large ribosomal subunit protein uL29 (RPL35) LDTP03999 1.97  LDD0289 
Large ribosomal subunit protein uL30 (RPL7) LDTP02944 0.85  LDD0289 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 4.82; 0.88; 1.62 ...  LDD0289 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 2.23; 2.57  LDD0289 
LIM domain and actin-binding protein 1 (LIMA1) LDTP13260 2.45  LDD0289 
LRP chaperone MESD (MESD) LDTP06191 1.53  LDD0289 
Macrophage-capping protein (CAPG) LDTP03877 20.00; 2.18  LDD0289 
Microtubule-associated protein 4 (MAP4) LDTP03404 1.89  LDD0289 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 0.83  LDD0289 
Muscleblind-like protein 1 (MBNL1) LDTP12478 2.85; 1.72  LDD0289 
Muscleblind-like protein 2 (MBNL2) LDTP07260 2.85; 0.78  LDD0289 
Muscleblind-like protein 3 (MBNL3) LDTP12630 1.72  LDD0289 
Myeloid-derived growth factor (MYDGF) LDTP10003 6.78  LDD0289 
Myosin light polypeptide 6 (MYL6) LDTP04875 1.27  LDD0289 
Myosin regulatory light chain 12B (MYL12B) LDTP00487 1.58  LDD0289 
N6-adenosine-methyltransferase non-catalytic subunit (METTL14) LDTP12234 1.87  LDD0289 
Nascent polypeptide-associated complex subunit alpha (NACA) LDTP05977 0.26; 1.10  LDD0289 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 2.19; 1.23  LDD0289 
Nuclear migration protein nudC (NUDC) LDTP13817 2.09  LDD0289 
Nucleolin (NCL) LDTP02990 2.50; 1.69; 1.92 ...  LDD0289 
Nucleolysin TIAR (TIAL1) LDTP05274 1.92  LDD0289 
Nucleophosmin (NPM1) LDTP02164 2.11; 2.07; 0.42  LDD0289 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 1.25; 5.68; 1.86  LDD0289 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 2.11; 1.86  LDD0289 
Oxysterol-binding protein-related protein 11 (OSBPL11) LDTP11367 4.25  LDD0289 
Perilipin-3 (PLIN3) LDTP01021 2.04  LDD0289 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 2.84; 4.36; 3.76 ...  LDD0289 
Plastin-3 (PLS3) LDTP02692 0.56; 0.81  LDD0289 
Platelet-activating factor acetylhydrolase IB subunit beta (PAFAH1B1) LDTP04015 1.82; 1.27  LDD0289 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 2.60; 2.06; 2.04  LDD0289 
Poly(rC)-binding protein 2 (PCBP2) LDTP06367 1.92; 1.04; 1.97  LDD0289 
Polyadenylate-binding protein 1 (PABPC1) LDTP02595 3.55; 1.62; 1.86 ...  LDD0289 
Polyadenylate-binding protein 4 (PABPC4) LDTP05821 1.15; 1.91  LDD0289 
Polypyrimidine tract-binding protein 1 (PTBP1) LDTP03364 1.71; 2.04  LDD0289 
Prefoldin subunit 3 (VBP1) LDTP04935 2.11  LDD0289 
Prefoldin subunit 6 (PFDN6) LDTP00573 0.69  LDD0289 
Prelamin-A/C (LMNA) LDTP01932 1.83; 2.82  LDD0289 
Profilin-1 (PFN1) LDTP02218 2.28; 2.62  LDD0289 
Programmed cell death protein 5 (PDCD5) LDTP00417 3.11; 5.78  LDD0289 
Proliferating cell nuclear antigen (PCNA) LDTP02596 1.60; 2.69  LDD0289 
Protein BUD31 homolog (BUD31) LDTP03935 1.39  LDD0289 
Protein FAM118B (FAM118B) LDTP15852 3.63  LDD0289 
Protein flightless-1 homolog (FLII) LDTP05734 1.51  LDD0289 
Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) LDTP13656 4.23; 1.87; 2.26 ...  LDD0289 
Protein LSM12 (LSM12) LDTP06780 1.66  LDD0289 
Protein mago nashi homolog 2 (MAGOHB) LDTP10071 1.91  LDD0289 
Protein NipSnap homolog 3A (NIPSNAP3A) LDTP18525 2.99; 3.21  LDD0289 
Protein phosphatase 1 regulatory subunit 12A (PPP1R12A) LDTP00495 4.89  LDD0289 
Protein RCC2 (RCC2) LDTP13020 2.27  LDD0289 
Protein S100-A11 (S100A11) LDTP03620 2.47; 2.27  LDD0289 
Protein SET (SET) LDTP05277 1.02  LDD0289 
Protein SGT1 homolog (SUGT1) LDTP13935 1.64; 3.40  LDD0289 
Protein TFG (TFG) LDTP09851 2.19  LDD0289 
Protein transport protein Sec23A (SEC23A) LDTP06390 1.70; 1.45  LDD0289 
Protein transport protein Sec23B (SEC23B) LDTP06391 2.53  LDD0289 
Protein UXT (UXT) LDTP13125 1.94  LDD0289 
Putative protein FAM10A5 (ST13P5) LDTP17811 1.78  LDD0289 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 1.56  LDD0289 
Pyridoxal phosphate homeostasis protein (PLPBP) LDTP14521 0.70; 2.48  LDD0289 
Rab GDP dissociation inhibitor alpha (GDI1) LDTP03574 1.88; 2.00  LDD0289 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 2.96; 3.01; 1.08 ...  LDD0289 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 11.08  LDD0289 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 3.91; 2.06; 3.27 ...  LDD0289 
Replication protein A 70 kDa DNA-binding subunit (RPA1) LDTP03397 0.91  LDD0289 
Reticulocalbin-1 (RCN1) LDTP06352 1.66  LDD0289 
Retinoblastoma-associated protein (RB1) LDTP02146 1.97  LDD0289 
Rho GDP-dissociation inhibitor 1 (ARHGDIA) LDTP04510 2.41; 2.03; 2.10 ...  LDD0289 
Rho guanine nucleotide exchange factor 2 (ARHGEF2) LDTP09950 1.27  LDD0289 
Ribosome biogenesis protein WDR12 (WDR12) LDTP11625 2.46  LDD0289 
RNA-binding protein 3 (RBM3) LDTP05226 2.07; 1.89  LDD0289 
RNA-binding protein EWS (EWSR1) LDTP05318 1.67  LDD0289 
RNA-binding protein FUS (FUS) LDTP03775 2.13; 1.75  LDD0289 
Serine/arginine-rich splicing factor 2 (SRSF2) LDTP05280 1.60  LDD0289 
Serine/arginine-rich splicing factor 8 (SRSF8) LDTP11117 1.60  LDD0289 
Serpin H1 (SERPINH1) LDTP04363 0.77  LDD0289 
Single-stranded DNA-binding protein, mitochondrial (SSBP1) LDTP05437 1.19; 3.41; 1.87 ...  LDD0289 
Small acidic protein (SMAP) LDTP19007 2.34  LDD0289 
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) LDTP00862 0.99; 1.62; 1.11 ...  LDD0289 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 1.75; 1.02; 1.36  LDD0289 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 0.93; 3.48  LDD0289 
Small ribosomal subunit protein eS19 (RPS19) LDTP03864 3.05  LDD0289 
Small ribosomal subunit protein eS24 (RPS24) LDTP05012 1.30; 2.71; 1.61  LDD0289 
Small ribosomal subunit protein eS26 (RPS26) LDTP05014 1.34  LDD0289 
Small ribosomal subunit protein eS27 (RPS27) LDTP03987 0.07  LDD0289 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 1.88; 1.45  LDD0289 
Small ribosomal subunit protein eS4, Y isoform 1 (RPS4Y1) LDTP14653 1.45  LDD0289 
Small ribosomal subunit protein eS4, Y isoform 2 (RPS4Y2) LDTP19820 1.45  LDD0289 
Small ribosomal subunit protein eS7 (RPS7) LDTP04958 1.60  LDD0289 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 1.99; 0.74; 6.28 ...  LDD0289 
Small ribosomal subunit protein uS11 (RPS14) LDTP04970 1.74  LDD0289 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 1.08  LDD0289 
Small ribosomal subunit protein uS13 (RPS18) LDTP04972 4.45; 0.05; 9.94  LDD0289 
Small ribosomal subunit protein uS15 (RPS13) LDTP04974 1.76; 2.25; 2.15  LDD0289 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 1.65; 2.17  LDD0289 
Small ribosomal subunit protein uS2 (RPSA) LDTP02312 1.59  LDD0289 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 1.71; 1.75; 1.55  LDD0289 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 1.81; 1.98  LDD0289 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 2.06; 1.71  LDD0289 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 1.93  LDD0289 
Splicing factor YJU2 (YJU2) LDTP11317 2.55  LDD0289 
Src substrate cortactin (CTTN) LDTP06094 1.96; 7.72; 2.07 ...  LDD0289 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 3.40; 1.16; 1.49 ...  LDD0289 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 1.73; 0.71; 2.13 ...  LDD0289 
Stromal cell-derived factor 2-like protein 1 (SDF2L1) LDTP16047 2.35  LDD0289 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 2.12; 1.45  LDD0289 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 3.59  LDD0289 
Structural maintenance of chromosomes protein 4 (SMC4) LDTP12606 1.81  LDD0289 
T-complex protein 1 subunit beta (CCT2) LDTP05113 1.99; 2.85; 20.00  LDD0289 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 1.51; 1.95  LDD0289 
T-complex protein 1 subunit eta (CCT7) LDTP10990 0.39  LDD0289 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 1.84; 1.96  LDD0289 
T-complex protein 1 subunit theta (CCT8) LDTP04390 1.58; 1.21; 1.49 ...  LDD0289 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 1.18  LDD0289 
T-complex protein 1 subunit zeta-2 (CCT6B) LDTP09777 1.18  LDD0289 
Tetratricopeptide repeat protein 1 (TTC1) LDTP15840 3.23  LDD0289 
Tetratricopeptide repeat protein 4 (TTC4) LDTP01678 2.03  LDD0289 
Transcription elongation factor A protein 1 (TCEA1) LDTP03209 1.82  LDD0289 
Transcription elongation factor SPT6 (SUPT6H) LDTP07928 1.88  LDD0289 
Transgelin-2 (TAGLN2) LDTP03846 4.77; 2.56; 2.09  LDD0289 
Translation initiation factor eIF2B subunit delta (EIF2B4) LDTP13318 3.01  LDD0289 
Translationally-controlled tumor protein (TPT1) LDTP02683 3.43; 1.48  LDD0289 
Transmembrane glycoprotein NMB (GPNMB) LDTP06237 3.37  LDD0289 
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WDR6) LDTP12296 1.91  LDD0289 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 2.61  LDD0289 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 2.86  LDD0289 
Tubulin beta chain (TUBB) LDTP02205 2.42; 1.55; 1.19 ...  LDD0289 
Tubulin beta-2A chain (TUBB2A) LDTP05998 10.03; 0.07; 4.96 ...  LDD0289 
Tubulin beta-2B chain (TUBB2B) LDTP11277 1.27; 1.95; 1.64 ...  LDD0289 
Tubulin beta-3 chain (TUBB3) LDTP05904 1.64; 1.58; 1.64 ...  LDD0289 
Tubulin beta-4A chain (TUBB4A) LDTP02037 1.69; 2.02; 1.80 ...  LDD0289 
Tubulin beta-4B chain (TUBB4B) LDTP05076 1.13; 1.70; 1.58 ...  LDD0289 
Tubulin beta-6 chain (TUBB6) LDTP11233 1.56; 1.75; 0.71 ...  LDD0289 
Tubulin gamma-1 chain (TUBG1) LDTP03213 2.51  LDD0289 
Tubulin gamma-2 chain (TUBG2) LDTP12512 2.51  LDD0289 
Tubulin-folding cofactor B (TBCB) LDTP10860 2.81; 2.13  LDD0289 
U6 snRNA-associated Sm-like protein LSm2 (LSM2) LDTP13946 1.27  LDD0289 
Ubiquilin-1 (UBQLN1) LDTP13626 2.04  LDD0289 
Ubiquitin-associated protein 2-like (UBAP2L) LDTP06060 14.75; 2.46  LDD0289 
Ubiquitin-fold modifier 1 (UFM1) LDTP04946 2.73  LDD0289 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 1.58  LDD0289 
Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) LDTP11534 1.93  LDD0289 
Vacuolar fusion protein CCZ1 homolog (CCZ1) LDTP14797 1.30  LDD0289 
Vasodilator-stimulated phosphoprotein (VASP) LDTP04372 1.79  LDD0289 
Vimentin (VIM) LDTP02297 2.24; 1.94; 1.01 ...  LDD0289 
Vinculin (VCL) LDTP02946 6.59; 7.25; 1.29  LDD0289 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 1.82  LDD0289 
WD repeat-containing protein 1 (WDR1) LDTP01118 2.15; 1.80; 4.14 ...  LDD0289 
WW domain-binding protein 2 (WBP2) LDTP10033 4.22; 1.44; 3.70  LDD0289 
Zinc finger CCHC domain-containing protein 8 (ZCCHC8) LDTP07496 0.39  LDD0289 
Zyxin (ZYX) LDTP06507 2.65; 2.77  LDD0289 
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Full Information of The Labelling Profiles of This Competitor

HHS-482
 Probe Info 
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 50 uM
Quantitative Method SILAC
Competitor Name JWB152
Competitor Concentration 50 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Skin
Disease Model Melanoma [ICD-11:2C82]
Model Name Human melanoma cell lysate (DM93)
Interaction Atlas ID  LDD0289  Download The Altas
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 50 uM
Quantitative Method SILAC
Competitor Name JWB152
Competitor Concentration 50 uM
In Vitro Experiment Model Model Type
Living cell
Derived Tissue
Skin
Disease Model Melanoma [ICD-11:2C82]
Model Name Human melanoma cells (DM93)
Interaction Atlas ID  LDD0294  Download The Altas

References

1 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.