Details of the Target

General Information of Target

Target ID LDTP16047
Target Name Stromal cell-derived factor 2-like protein 1 (SDF2L1)
Gene Name SDF2L1
Gene ID 23753
Synonyms
Stromal cell-derived factor 2-like protein 1; SDF2-like protein 1; PWP1-interacting protein 8
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGSSSEASFRSAQASCSGARRQGLGRGDQNLSVMPPNGRAQTHTPGWVSDPLVLGAQVHG
GCRGIEALSVSSGSWSSATVWILTGLGLGLSRPFLPGATVLRDRPLGSAFELSYDQKKAP
LRLQ
Target Bioclass
Other
Subcellular location
Endoplasmic reticulum lumen
Uniprot ID
Q9HCN8
Ensemble ID
ENST00000248958.5
HGNC ID
HGNC:10676

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 13 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
BTD
 Probe Info  		C92(1.30)  LDD1700  [1]
HHS-482
 Probe Info  		Y81(0.93)  LDD0285  [2]
Acrolein
 Probe Info  		N.A.  LDD0222  [3]
DBIA
 Probe Info  		C92(1.01)  LDD0532  [4]
5E-2FA
 Probe Info  		H153(0.00); H197(0.00)  LDD2235  [5]
m-APA
 Probe Info  		N.A.  LDD2232  [5]
4-Iodoacetamidophenylacetylene
 Probe Info  		C149(0.00); C92(0.00); C38(0.00)  LDD0038  [6]
IA-alkyne
 Probe Info  		C149(0.00); C38(0.00)  LDD0036  [6]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [6]
PPMS
 Probe Info  		N.A.  LDD0008  [7]
SF
 Probe Info  		N.A.  LDD0028  [8]
NAIA_5
 Probe Info  		C149(0.00); C92(0.00); C38(0.00)  LDD2223  [9]
HHS-465
 Probe Info  		N.A.  LDD2240  [10]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C92(0.98); C38(1.08)  LDD1507  [11]
 LDCM0215  AC10 HCT 116 C92(1.01)  LDD0532  [4]
 LDCM0226  AC11 HCT 116 C92(0.74)  LDD0543  [4]
 LDCM0230  AC113 HEK-293T C92(0.77)  LDD0828  [4]
 LDCM0231  AC114 HEK-293T C92(0.96)  LDD0829  [4]
 LDCM0232  AC115 HEK-293T C92(1.15)  LDD0830  [4]
 LDCM0233  AC116 HEK-293T C92(1.43)  LDD0831  [4]
 LDCM0234  AC117 HEK-293T C92(0.95)  LDD0832  [4]
 LDCM0235  AC118 HEK-293T C92(0.94)  LDD0833  [4]
 LDCM0236  AC119 HEK-293T C92(0.94)  LDD0834  [4]
 LDCM0237  AC12 HCT 116 C92(0.77)  LDD0554  [4]
 LDCM0238  AC120 HEK-293T C92(1.20)  LDD0836  [4]
 LDCM0239  AC121 HEK-293T C92(0.75)  LDD0837  [4]
 LDCM0240  AC122 HEK-293T C92(0.67)  LDD0838  [4]
 LDCM0241  AC123 HEK-293T C92(0.81)  LDD0839  [4]
 LDCM0242  AC124 HEK-293T C92(0.73)  LDD0840  [4]
 LDCM0243  AC125 HEK-293T C92(0.81)  LDD0841  [4]
 LDCM0244  AC126 HEK-293T C92(0.80)  LDD0842  [4]
 LDCM0245  AC127 HEK-293T C92(0.57)  LDD0843  [4]
 LDCM0259  AC14 HCT 116 C92(1.15)  LDD0576  [4]
 LDCM0263  AC143 HEK-293T C92(0.76)  LDD0861  [4]
 LDCM0264  AC144 HEK-293T C92(1.02)  LDD0862  [4]
 LDCM0265  AC145 HEK-293T C92(0.86)  LDD0863  [4]
 LDCM0266  AC146 HEK-293T C92(0.70)  LDD0864  [4]
 LDCM0267  AC147 HEK-293T C92(0.89)  LDD0865  [4]
 LDCM0268  AC148 HEK-293T C92(0.74)  LDD0866  [4]
 LDCM0269  AC149 HEK-293T C92(0.56)  LDD0867  [4]
 LDCM0270  AC15 HCT 116 C92(1.46)  LDD0587  [4]
 LDCM0271  AC150 HEK-293T C92(0.81)  LDD0869  [4]
 LDCM0272  AC151 HEK-293T C92(0.78)  LDD0870  [4]
 LDCM0273  AC152 HEK-293T C92(1.08)  LDD0871  [4]
 LDCM0274  AC153 HEK-293T C92(1.10)  LDD0872  [4]
 LDCM0621  AC154 HEK-293T C92(1.01)  LDD2162  [4]
 LDCM0622  AC155 HEK-293T C92(0.91)  LDD2163  [4]
 LDCM0623  AC156 HEK-293T C92(1.16)  LDD2164  [4]
 LDCM0624  AC157 HEK-293T C92(1.21)  LDD2165  [4]
 LDCM0276  AC17 HEK-293T C92(1.01); C38(0.99)  LDD1515  [11]
 LDCM0277  AC18 HEK-293T C92(1.03); C149(1.04)  LDD1516  [11]
 LDCM0278  AC19 HEK-293T C92(1.36); C149(1.29)  LDD1517  [11]
 LDCM0279  AC2 HEK-293T C92(1.02); C149(0.97)  LDD1518  [11]
 LDCM0280  AC20 HEK-293T C92(0.97); C149(1.08); C38(1.04)  LDD1519  [11]
 LDCM0281  AC21 HEK-293T C92(1.03); C149(1.02)  LDD1520  [11]
 LDCM0282  AC22 HEK-293T C92(1.05); C38(1.01)  LDD1521  [11]
 LDCM0283  AC23 HEK-293T C92(0.98); C38(0.98)  LDD1522  [11]
 LDCM0284  AC24 HEK-293T C92(0.89); C149(1.03)  LDD1523  [11]
 LDCM0285  AC25 HEK-293T C92(1.04); C38(1.00)  LDD1524  [11]
 LDCM0286  AC26 HEK-293T C92(1.06); C149(1.01)  LDD1525  [11]
 LDCM0287  AC27 HEK-293T C92(1.03); C149(1.09)  LDD1526  [11]
 LDCM0288  AC28 HEK-293T C92(1.01); C149(1.15); C38(1.03)  LDD1527  [11]
 LDCM0289  AC29 HEK-293T C92(1.01); C149(1.04)  LDD1528  [11]
 LDCM0290  AC3 HEK-293T C92(1.04); C149(1.03)  LDD1529  [11]
 LDCM0291  AC30 HEK-293T C92(1.04); C38(0.98)  LDD1530  [11]
 LDCM0292  AC31 HEK-293T C92(1.01); C38(0.94)  LDD1531  [11]
 LDCM0293  AC32 HEK-293T C92(0.94); C149(1.07)  LDD1532  [11]
 LDCM0294  AC33 HEK-293T C92(1.04); C38(1.14)  LDD1533  [11]
 LDCM0295  AC34 HEK-293T C92(1.08); C149(1.11)  LDD1534  [11]
 LDCM0296  AC35 HCT 116 C92(1.09)  LDD0613  [4]
 LDCM0297  AC36 HCT 116 C92(1.01)  LDD0614  [4]
 LDCM0298  AC37 HCT 116 C92(0.93)  LDD0615  [4]
 LDCM0299  AC38 HCT 116 C92(1.32)  LDD0616  [4]
 LDCM0300  AC39 HCT 116 C92(1.02)  LDD0617  [4]
 LDCM0301  AC4 HEK-293T C92(0.95); C149(1.06); C38(1.02)  LDD1540  [11]
 LDCM0302  AC40 HCT 116 C92(1.00)  LDD0619  [4]
 LDCM0303  AC41 HCT 116 C92(1.21)  LDD0620  [4]
 LDCM0304  AC42 HCT 116 C92(0.85)  LDD0621  [4]
 LDCM0305  AC43 HCT 116 C92(1.45)  LDD0622  [4]
 LDCM0306  AC44 HCT 116 C92(1.38)  LDD0623  [4]
 LDCM0307  AC45 HCT 116 C92(0.84)  LDD0624  [4]
 LDCM0308  AC46 HEK-293T C92(1.05); C38(1.04)  LDD1547  [11]
 LDCM0309  AC47 HEK-293T C92(0.99); C38(1.05)  LDD1548  [11]
 LDCM0310  AC48 HEK-293T C92(0.95); C149(1.08)  LDD1549  [11]
 LDCM0311  AC49 HEK-293T C92(1.02); C38(1.09)  LDD1550  [11]
 LDCM0312  AC5 HEK-293T C92(1.06); C149(1.02)  LDD1551  [11]
 LDCM0313  AC50 HEK-293T C92(1.01); C149(1.06)  LDD1552  [11]
 LDCM0314  AC51 HEK-293T C92(0.95); C149(1.13)  LDD1553  [11]
 LDCM0315  AC52 HEK-293T C92(0.98); C149(1.08); C38(1.03)  LDD1554  [11]
 LDCM0316  AC53 HEK-293T C92(0.93); C149(1.13)  LDD1555  [11]
 LDCM0317  AC54 HEK-293T C92(0.96); C38(1.02)  LDD1556  [11]
 LDCM0318  AC55 HEK-293T C92(0.96); C38(1.06)  LDD1557  [11]
 LDCM0319  AC56 HEK-293T C92(0.98); C149(1.08)  LDD1558  [11]
 LDCM0320  AC57 HEK-293T C92(1.31)  LDD0918  [4]
 LDCM0321  AC58 HEK-293T C92(0.80)  LDD0919  [4]
 LDCM0322  AC59 HEK-293T C92(1.29)  LDD0920  [4]
 LDCM0323  AC6 HCT 116 C92(1.01)  LDD0640  [4]
 LDCM0324  AC60 HEK-293T C92(1.15)  LDD0922  [4]
 LDCM0325  AC61 HEK-293T C92(1.60)  LDD0923  [4]
 LDCM0326  AC62 HEK-293T C92(2.66)  LDD0924  [4]
 LDCM0327  AC63 HEK-293T C92(1.81)  LDD0925  [4]
 LDCM0328  AC64 HEK-293T C92(1.65)  LDD0926  [4]
 LDCM0329  AC65 HEK-293T C92(1.43)  LDD0927  [4]
 LDCM0330  AC66 HEK-293T C92(1.52)  LDD0928  [4]
 LDCM0331  AC67 HEK-293T C92(2.04)  LDD0929  [4]
 LDCM0332  AC68 HCT 116 C92(0.81)  LDD0649  [4]
 LDCM0333  AC69 HCT 116 C92(0.80)  LDD0650  [4]
 LDCM0334  AC7 HCT 116 C92(0.83)  LDD0651  [4]
 LDCM0335  AC70 HCT 116 C92(0.81)  LDD0652  [4]
 LDCM0336  AC71 HCT 116 C92(0.60)  LDD0653  [4]
 LDCM0337  AC72 HCT 116 C92(1.04)  LDD0654  [4]
 LDCM0338  AC73 HCT 116 C92(1.10)  LDD0655  [4]
 LDCM0339  AC74 HCT 116 C92(1.41)  LDD0656  [4]
 LDCM0340  AC75 HCT 116 C92(0.95)  LDD0657  [4]
 LDCM0341  AC76 HCT 116 C92(0.74)  LDD0658  [4]
 LDCM0342  AC77 HCT 116 C92(1.00)  LDD0659  [4]
 LDCM0343  AC78 HCT 116 C92(0.87)  LDD0660  [4]
 LDCM0344  AC79 HCT 116 C92(0.83)  LDD0661  [4]
 LDCM0345  AC8 HCT 116 C92(1.05)  LDD0662  [4]
 LDCM0346  AC80 HCT 116 C92(0.97)  LDD0663  [4]
 LDCM0347  AC81 HCT 116 C92(0.60)  LDD0664  [4]
 LDCM0348  AC82 HCT 116 C92(0.89)  LDD0665  [4]
 LDCM0349  AC83 HCT 116 C92(1.05)  LDD0666  [4]
 LDCM0350  AC84 HCT 116 C92(1.06)  LDD0667  [4]
 LDCM0351  AC85 HCT 116 C92(1.40)  LDD0668  [4]
 LDCM0352  AC86 HCT 116 C92(1.08)  LDD0669  [4]
 LDCM0353  AC87 HCT 116 C92(1.38)  LDD0670  [4]
 LDCM0354  AC88 HCT 116 C92(1.23)  LDD0671  [4]
 LDCM0355  AC89 HCT 116 C92(1.14)  LDD0672  [4]
 LDCM0357  AC90 HCT 116 C92(0.99)  LDD0674  [4]
 LDCM0358  AC91 HCT 116 C92(1.32)  LDD0675  [4]
 LDCM0359  AC92 HCT 116 C92(1.28)  LDD0676  [4]
 LDCM0360  AC93 HCT 116 C92(1.05)  LDD0677  [4]
 LDCM0361  AC94 HCT 116 C92(1.25)  LDD0678  [4]
 LDCM0362  AC95 HCT 116 C92(1.49)  LDD0679  [4]
 LDCM0363  AC96 HCT 116 C92(1.24)  LDD0680  [4]
 LDCM0364  AC97 HCT 116 C92(1.46)  LDD0681  [4]
 LDCM0248  AKOS034007472 HCT 116 C92(0.85)  LDD0565  [4]
 LDCM0356  AKOS034007680 HCT 116 C92(0.63)  LDD0673  [4]
 LDCM0275  AKOS034007705 HCT 116 C92(1.19)  LDD0592  [4]
 LDCM0020  ARS-1620 HCC44 C92(0.98)  LDD2171  [4]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [3]
 LDCM0367  CL1 HCT 116 C92(0.86)  LDD0684  [4]
 LDCM0368  CL10 HCT 116 C92(0.82)  LDD0685  [4]
 LDCM0369  CL100 HEK-293T C92(1.08); C149(0.99); C38(1.09)  LDD1573  [11]
 LDCM0370  CL101 HCT 116 C92(0.93)  LDD0687  [4]
 LDCM0371  CL102 HCT 116 C92(0.89)  LDD0688  [4]
 LDCM0372  CL103 HCT 116 C92(0.87)  LDD0689  [4]
 LDCM0373  CL104 HCT 116 C92(0.77)  LDD0690  [4]
 LDCM0374  CL105 HEK-293T C92(1.03); C149(1.09)  LDD1578  [11]
 LDCM0375  CL106 HEK-293T C92(0.98); C149(1.16); C38(1.04)  LDD1579  [11]
 LDCM0376  CL107 HEK-293T C92(0.95); C149(1.06); C38(0.98)  LDD1580  [11]
 LDCM0377  CL108 HEK-293T C92(0.97); C149(0.99); C38(1.00)  LDD1581  [11]
 LDCM0378  CL109 HEK-293T C92(1.00); C149(1.11)  LDD1582  [11]
 LDCM0379  CL11 HCT 116 C92(0.55)  LDD0696  [4]
 LDCM0380  CL110 HEK-293T C92(1.01); C149(1.25); C38(1.06)  LDD1584  [11]
 LDCM0381  CL111 HEK-293T C92(1.08); C149(1.16); C38(0.90)  LDD1585  [11]
 LDCM0382  CL112 HEK-293T C92(1.08); C149(1.05); C38(1.09)  LDD1586  [11]
 LDCM0383  CL113 HEK-293T C92(1.04); C149(1.08)  LDD1587  [11]
 LDCM0384  CL114 HEK-293T C92(1.05); C149(1.22); C38(1.02)  LDD1588  [11]
 LDCM0385  CL115 HEK-293T C92(1.01); C149(1.07); C38(0.88)  LDD1589  [11]
 LDCM0386  CL116 HEK-293T C92(0.96); C149(1.06); C38(1.02)  LDD1590  [11]
 LDCM0387  CL117 HCT 116 C92(1.23)  LDD0704  [4]
 LDCM0388  CL118 HCT 116 C92(0.87)  LDD0705  [4]
 LDCM0389  CL119 HCT 116 C92(0.87)  LDD0706  [4]
 LDCM0390  CL12 HCT 116 C92(0.94)  LDD0707  [4]
 LDCM0391  CL120 HCT 116 C92(1.08)  LDD0708  [4]
 LDCM0392  CL121 HEK-293T C92(0.98); C149(1.15)  LDD1596  [11]
 LDCM0393  CL122 HEK-293T C92(1.01); C149(1.15); C38(0.96)  LDD1597  [11]
 LDCM0394  CL123 HEK-293T C92(1.14); C149(1.09); C38(0.97)  LDD1598  [11]
 LDCM0395  CL124 HEK-293T C92(1.00); C149(1.21); C38(1.03)  LDD1599  [11]
 LDCM0396  CL125 HEK-293T C92(0.38)  LDD0994  [4]
 LDCM0397  CL126 HEK-293T C92(1.15)  LDD0995  [4]
 LDCM0398  CL127 HEK-293T C92(0.53)  LDD0996  [4]
 LDCM0399  CL128 HEK-293T C92(0.51)  LDD0997  [4]
 LDCM0400  CL13 HCT 116 C92(0.97)  LDD0717  [4]
 LDCM0401  CL14 HCT 116 C92(0.76)  LDD0718  [4]
 LDCM0402  CL15 HCT 116 C92(0.70)  LDD0719  [4]
 LDCM0403  CL16 HEK-293T C92(1.00); C149(0.96); C38(0.98)  LDD1607  [11]
 LDCM0404  CL17 HCT 116 C92(1.06)  LDD0721  [4]
 LDCM0405  CL18 HCT 116 C92(1.27)  LDD0722  [4]
 LDCM0406  CL19 HCT 116 C92(1.30)  LDD0723  [4]
 LDCM0407  CL2 HCT 116 C92(1.06)  LDD0724  [4]
 LDCM0408  CL20 HCT 116 C92(1.43)  LDD0725  [4]
 LDCM0409  CL21 HCT 116 C92(1.23)  LDD0726  [4]
 LDCM0410  CL22 HCT 116 C92(1.00)  LDD0727  [4]
 LDCM0411  CL23 HCT 116 C92(0.63)  LDD0728  [4]
 LDCM0412  CL24 HCT 116 C92(1.15)  LDD0729  [4]
 LDCM0413  CL25 HCT 116 C92(1.63)  LDD0730  [4]
 LDCM0414  CL26 HCT 116 C92(0.94)  LDD0731  [4]
 LDCM0415  CL27 HCT 116 C92(1.15)  LDD0732  [4]
 LDCM0416  CL28 HCT 116 C92(1.22)  LDD0733  [4]
 LDCM0417  CL29 HCT 116 C92(1.33)  LDD0734  [4]
 LDCM0418  CL3 HCT 116 C92(0.60)  LDD0735  [4]
 LDCM0419  CL30 HCT 116 C92(0.88)  LDD0736  [4]
 LDCM0420  CL31 HCT 116 C92(1.19)  LDD0737  [4]
 LDCM0421  CL32 HEK-293T C92(0.83)  LDD1019  [4]
 LDCM0422  CL33 HEK-293T C92(0.71)  LDD1020  [4]
 LDCM0423  CL34 HEK-293T C92(1.42)  LDD1021  [4]
 LDCM0424  CL35 HEK-293T C92(1.03)  LDD1022  [4]
 LDCM0425  CL36 HEK-293T C92(0.80)  LDD1023  [4]
 LDCM0426  CL37 HEK-293T C92(0.80)  LDD1024  [4]
 LDCM0428  CL39 HEK-293T C92(0.85)  LDD1026  [4]
 LDCM0429  CL4 HCT 116 C92(1.05)  LDD0746  [4]
 LDCM0430  CL40 HEK-293T C92(0.89)  LDD1028  [4]
 LDCM0431  CL41 HEK-293T C92(0.70)  LDD1029  [4]
 LDCM0432  CL42 HEK-293T C92(0.77)  LDD1030  [4]
 LDCM0433  CL43 HEK-293T C92(0.80)  LDD1031  [4]
 LDCM0434  CL44 HEK-293T C92(1.22)  LDD1032  [4]
 LDCM0435  CL45 HEK-293T C92(0.89)  LDD1033  [4]
 LDCM0436  CL46 HEK-293T C92(1.09); C38(1.13)  LDD1640  [11]
 LDCM0437  CL47 HEK-293T C92(1.01); C38(1.03)  LDD1641  [11]
 LDCM0438  CL48 HEK-293T C92(1.02); C149(1.07)  LDD1642  [11]
 LDCM0439  CL49 HEK-293T C92(1.00); C149(0.99)  LDD1643  [11]
 LDCM0440  CL5 HCT 116 C92(1.02)  LDD0757  [4]
 LDCM0441  CL50 HEK-293T C92(1.02); C149(1.16); C38(1.05)  LDD1645  [11]
 LDCM0443  CL52 HEK-293T C92(1.01); C149(1.04); C38(0.92)  LDD1646  [11]
 LDCM0444  CL53 HEK-293T C92(1.08); C38(1.10)  LDD1647  [11]
 LDCM0445  CL54 HEK-293T C92(1.06); C149(1.15)  LDD1648  [11]
 LDCM0446  CL55 HEK-293T C92(1.01); C149(1.14)  LDD1649  [11]
 LDCM0447  CL56 HEK-293T C92(1.08); C149(1.18); C38(1.15)  LDD1650  [11]
 LDCM0448  CL57 HEK-293T C92(1.43); C149(1.30)  LDD1651  [11]
 LDCM0449  CL58 HEK-293T C92(1.10); C38(1.08)  LDD1652  [11]
 LDCM0450  CL59 HEK-293T C92(1.02); C38(1.04)  LDD1653  [11]
 LDCM0451  CL6 HCT 116 C92(1.24)  LDD0768  [4]
 LDCM0452  CL60 HEK-293T C92(1.08); C149(1.17)  LDD1655  [11]
 LDCM0453  CL61 HEK-293T C92(0.97); C149(0.94)  LDD1656  [11]
 LDCM0454  CL62 HEK-293T C92(0.97); C149(1.13); C38(1.01)  LDD1657  [11]
 LDCM0455  CL63 HEK-293T C92(0.93); C149(1.01); C38(0.97)  LDD1658  [11]
 LDCM0456  CL64 HEK-293T C92(1.13); C149(1.18); C38(0.98)  LDD1659  [11]
 LDCM0457  CL65 HEK-293T C92(1.08); C38(1.12)  LDD1660  [11]
 LDCM0458  CL66 HEK-293T C92(1.05); C149(1.07)  LDD1661  [11]
 LDCM0459  CL67 HEK-293T C92(1.02); C149(1.20)  LDD1662  [11]
 LDCM0460  CL68 HEK-293T C92(1.10); C149(1.04); C38(1.10)  LDD1663  [11]
 LDCM0461  CL69 HEK-293T C92(1.01); C149(1.18)  LDD1664  [11]
 LDCM0462  CL7 HCT 116 C92(0.75)  LDD0779  [4]
 LDCM0463  CL70 HEK-293T C92(1.08); C38(1.40)  LDD1666  [11]
 LDCM0464  CL71 HEK-293T C92(1.03); C38(1.14)  LDD1667  [11]
 LDCM0465  CL72 HEK-293T C92(1.06); C149(1.11)  LDD1668  [11]
 LDCM0466  CL73 HEK-293T C92(1.03); C149(0.98)  LDD1669  [11]
 LDCM0467  CL74 HEK-293T C92(0.97); C149(1.04); C38(0.99)  LDD1670  [11]
 LDCM0469  CL76 HEK-293T C92(1.03); C149(1.00); C38(1.05)  LDD1672  [11]
 LDCM0470  CL77 HEK-293T C92(1.02); C38(1.08)  LDD1673  [11]
 LDCM0471  CL78 HEK-293T C92(1.05); C149(1.08)  LDD1674  [11]
 LDCM0472  CL79 HEK-293T C92(0.99); C149(1.14)  LDD1675  [11]
 LDCM0473  CL8 HCT 116 C92(1.26)  LDD0790  [4]
 LDCM0474  CL80 HEK-293T C92(0.98); C149(1.06); C38(1.01)  LDD1677  [11]
 LDCM0475  CL81 HEK-293T C92(0.96); C149(1.17)  LDD1678  [11]
 LDCM0476  CL82 HEK-293T C92(0.99); C38(1.06)  LDD1679  [11]
 LDCM0477  CL83 HEK-293T C92(0.99); C38(1.07)  LDD1680  [11]
 LDCM0478  CL84 HEK-293T C92(1.00); C149(1.08)  LDD1681  [11]
 LDCM0479  CL85 HEK-293T C92(0.97); C149(0.87)  LDD1682  [11]
 LDCM0480  CL86 HEK-293T C92(0.96); C149(0.90); C38(0.97)  LDD1683  [11]
 LDCM0481  CL87 HEK-293T C92(0.98); C149(0.84); C38(0.96)  LDD1684  [11]
 LDCM0482  CL88 HEK-293T C92(0.98); C149(0.82); C38(0.99)  LDD1685  [11]
 LDCM0483  CL89 HEK-293T C92(0.97); C38(1.14)  LDD1686  [11]
 LDCM0484  CL9 HCT 116 C92(1.04)  LDD0801  [4]
 LDCM0485  CL90 HEK-293T C92(1.50); C149(1.22)  LDD1688  [11]
 LDCM0486  CL91 HEK-293T C92(0.98); C149(0.96)  LDD1689  [11]
 LDCM0487  CL92 HEK-293T C92(0.97); C149(1.02); C38(1.00)  LDD1690  [11]
 LDCM0488  CL93 HEK-293T C92(1.09); C149(1.17)  LDD1691  [11]
 LDCM0489  CL94 HEK-293T C92(1.03); C38(1.09)  LDD1692  [11]
 LDCM0490  CL95 HEK-293T C92(1.22); C38(1.07)  LDD1693  [11]
 LDCM0491  CL96 HEK-293T C92(1.01); C149(0.84)  LDD1694  [11]
 LDCM0492  CL97 HEK-293T C92(1.02); C149(1.08)  LDD1695  [11]
 LDCM0493  CL98 HEK-293T C92(1.01); C149(1.08); C38(0.93)  LDD1696  [11]
 LDCM0494  CL99 HEK-293T C92(1.00); C149(0.98); C38(0.94)  LDD1697  [11]
 LDCM0495  E2913 HEK-293T C92(1.01); C149(1.07); C38(0.95)  LDD1698  [11]
 LDCM0468  Fragment33 HEK-293T C92(0.95); C149(1.00); C38(0.99)  LDD1671  [11]
 LDCM0427  Fragment51 HEK-293T C92(1.08)  LDD1025  [4]
 LDCM0123  JWB131 DM93 Y81(0.93)  LDD0285  [2]
 LDCM0124  JWB142 DM93 Y81(1.01)  LDD0286  [2]
 LDCM0125  JWB146 DM93 Y81(1.36)  LDD0287  [2]
 LDCM0126  JWB150 DM93 Y81(4.71)  LDD0288  [2]
 LDCM0127  JWB152 DM93 Y81(2.35)  LDD0289  [2]
 LDCM0128  JWB198 DM93 Y81(2.01)  LDD0290  [2]
 LDCM0129  JWB202 DM93 Y81(1.47)  LDD0291  [2]
 LDCM0130  JWB211 DM93 Y81(0.91)  LDD0292  [2]
 LDCM0022  KB02 HEK-293T C92(0.88); C149(0.88); C38(0.96)  LDD1492  [11]
 LDCM0023  KB03 HEK-293T C92(0.97); C149(1.02); C38(0.87)  LDD1497  [11]
 LDCM0024  KB05 COLO792 C38(1.37)  LDD3310  [12]
 LDCM0109  NEM HeLa N.A.  LDD0227  [3]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C38(1.23); C92(0.90)  LDD2099  [1]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C38(0.80)  LDD2107  [1]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C38(0.64); C92(0.75)  LDD2125  [1]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C38(0.99)  LDD2127  [1]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C92(1.05)  LDD2136  [1]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C92(1.00)  LDD2137  [1]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C92(1.30)  LDD1700  [1]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C92(0.67)  LDD2140  [1]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C38(1.13)  LDD2144  [1]
 LDCM0021  THZ1 HCT 116 C92(0.98)  LDD2173  [4]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) SGT family O43765
Small glutamine-rich tetratricopeptide repeat-containing protein beta (SGTB) SGT family Q96EQ0

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
2 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
3 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
4 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
5 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
6 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
7 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
8 Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529022. doi: 10.1101/2023.02.17.529022.
Mass spectrometry data entry: PXD039931
9 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
10 Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation. Cell Chem Biol. 2022 Dec 15;29(12):1709-1720.e7. doi: 10.1016/j.chembiol.2022.11.008. Epub 2022 Dec 6.
Mass spectrometry data entry: PXD038010
11 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
12 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840