Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0124
Competitor Name
JWB142
Synonyms
SCHEMBL22558334
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 391.4
Lipid-water partition coefficient (xlogp) 4.5
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C21H17N3O3S
IUPAC Name
3-(4-methoxyphenyl)-1-(4-phenylphenyl)sulfonyl-1,2,4-triazole
Canonical SMILES
COC1=CC=C(C=C1)C2=NN(C=N2)S(=O)(=O)C3=CC=C(C=C3)C4=CC=CC=C4
InChI
InChI=1S/C21H17N3O3S/c1-27-19-11-7-18(8-12-19)21-22-15-24(23-21)28(25,26)20-13-9-17(10-14-20)16-5-3-2-4-6-16/h2-15H,1H3
InChIKey
KPJVQDWZAVSQNX-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
HHS-482
 Probe Info  		50 uM Human melanoma cell lysate (DM93) [1]

Target(s) List of this Competitor

293 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
(3R)-3-hydroxyacyl-CoA dehydrogenase (HSD17B8) LDTP09770 0.77  LDD0286 
1,4-alpha-glucan-branching enzyme (GBE1) LDTP05419 0.92  LDD0286 
14 kDa phosphohistidine phosphatase (PHPT1) LDTP12543 0.51; 0.47  LDD0286 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 0.57  LDD0286 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 0.65  LDD0286 
26S proteasome non-ATPase regulatory subunit 3 (PSMD3) LDTP00714 1.14  LDD0286 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 0.72  LDD0286 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 0.84  LDD0286 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 3.86  LDD0286 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 0.71  LDD0286 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 1.61  LDD0286 
5'-3' exoribonuclease 2 (XRN2) LDTP11701 1.05  LDD0286 
6-phosphogluconate dehydrogenase, decarboxylating (PGD) LDTP04499 0.99  LDD0286 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 0.25; 0.74; 0.81 ...  LDD0286 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 0.59  LDD0286 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 1.65  LDD0286 
Acetyl-CoA carboxylase 1 (ACACA) LDTP05742 0.44  LDD0286 
Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) LDTP12463 0.33  LDD0286 
Actin, alpha cardiac muscle 1 (ACTC1) LDTP05069 0.49  LDD0286 
Actin, cytoplasmic 1 (ACTB) LDTP04876 0.44; 1.32; 0.46 ...  LDD0286 
Adenosylhomocysteinase (AHCY) LDTP03242 0.51; 0.57  LDD0286 
Adenylosuccinate synthetase isozyme 2 (ADSS2) LDTP03541 0.83  LDD0286 
ADP-ribose pyrophosphatase, mitochondrial (NUDT9) LDTP11318 0.72  LDD0286 
ADP-ribosylation factor 1 (ARF1) LDTP05192 0.72; 1.04; 0.92  LDD0286 
ADP-ribosylation factor 3 (ARF3) LDTP04907 0.72; 1.04; 0.92  LDD0286 
ADP-ribosylation factor 4 (ARF4) LDTP02942 0.72; 1.04  LDD0286 
ADP-ribosylation factor 5 (ARF5) LDTP05193 0.72; 1.04  LDD0286 
ADP-sugar pyrophosphatase (NUDT5) LDTP13462 1.35  LDD0286 
Aflatoxin B1 aldehyde reductase member 2 (AKR7A2) LDTP00776 0.55; 0.88; 3.21 ...  LDD0286 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 0.50; 0.30  LDD0286 
Alcohol dehydrogenase class-3 (ADH5) LDTP02587 1.93; 0.68  LDD0286 
Aldo-keto reductase family 1 member A1 (AKR1A1) LDTP02729 1.03  LDD0286 
Alpha-aminoadipic semialdehyde synthase, mitochondrial (AASS) LDTP13186 0.79; 0.13; 1.61  LDD0286 
Alpha-enolase (ENO1) LDTP02159 1.11; 0.51; 2.82 ...  LDD0286 
Amidophosphoribosyltransferase (PPAT) LDTP05480 0.57  LDD0286 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 0.07; 0.79  LDD0286 
Asparagine synthetase [glutamine-hydrolyzing] (ASNS) LDTP02264 0.53  LDD0286 
Asparagine--tRNA ligase, cytoplasmic (NARS1) LDTP00866 0.94; 0.76; 0.38 ...  LDD0286 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 9.29; 0.59; 0.95  LDD0286 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 3.13; 1.07; 1.51  LDD0286 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 0.77; 2.01  LDD0286 
ATP-citrate synthase (ACLY) LDTP04561 0.65; 0.60; 1.15 ...  LDD0286 
ATP-dependent 6-phosphofructokinase, liver type (PFKL) LDTP02925 0.83  LDD0286 
ATP-dependent 6-phosphofructokinase, muscle type (PFKM) LDTP02261 0.93  LDD0286 
ATP-dependent RNA helicase A (DHX9) LDTP05550 0.37; 0.66  LDD0286 
ATP-dependent RNA helicase DDX1 (DDX1) LDTP09766 0.37  LDD0286 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 1.32  LDD0286 
ATPase MORC2 (MORC2) LDTP14308 1.42  LDD0286 
Bifunctional coenzyme A synthase (COASY) LDTP05736 0.69  LDD0286 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 0.88  LDD0286 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 2.49  LDD0286 
Biliverdin reductase A (BLVRA) LDTP04552 0.38  LDD0286 
Biotinidase (BTD) LDTP04030 0.98  LDD0286 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 0.80; 0.58; 1.10 ...  LDD0286 
Calcyclin-binding protein (CACYBP) LDTP12163 1.53; 0.88; 1.09  LDD0286 
Carbonyl reductase [NADPH] 1 (CBR1) LDTP02831 2.43  LDD0286 
Carbonyl reductase [NADPH] 3 (CBR3) LDTP01321 0.46  LDD0286 
Catalase (CAT) LDTP02001 0.75  LDD0286 
Cathepsin B (CTSB) LDTP02223 0.57; 0.67; 0.59 ...  LDD0286 
Cathepsin D (CTSD) LDTP02198 1.30; 1.26  LDD0286 
Cathepsin Z (CTSZ) LDTP13147 0.59; 0.99; 1.44 ...  LDD0286 
Citrate synthase, mitochondrial (CS) LDTP01205 2.03; 0.73; 0.73  LDD0286 
Cleavage and polyadenylation specificity factor subunit 5 (NUDT21) LDTP00873 1.41  LDD0286 
CTP synthase 1 (CTPS1) LDTP02922 0.40; 0.33; 0.70  LDD0286 
Cyclin-dependent kinase 1 (CDK1) LDTP02149 0.60; 1.06; 0.63 ...  LDD0286 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 0.60; 0.63  LDD0286 
Cystathionine gamma-lyase (CTH) LDTP03656 1.46  LDD0286 
Cysteine--tRNA ligase, cytoplasmic (CARS1) LDTP04263 0.50  LDD0286 
Cytochrome c oxidase assembly factor 7 (COA7) LDTP10137 0.68  LDD0286 
Cytoglobin (CYGB) LDTP09656 1.24; 3.24  LDD0286 
Cytosol aminopeptidase (LAP3) LDTP03455 0.81  LDD0286 
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 3.91; 1.00  LDD0286 
Dehydrogenase/reductase SDR family member 11 (DHRS11) LDTP07678 0.42  LDD0286 
Dihydropteridine reductase (QDPR) LDTP02342 0.77  LDD0286 
Dipeptidyl peptidase 3 (DPP3) LDTP12803 0.68  LDD0286 
DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 1.25  LDD0286 
DNA replication licensing factor MCM2 (MCM2) LDTP04286 0.61  LDD0286 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 2.84  LDD0286 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 1.01  LDD0286 
DNA replication licensing factor MCM5 (MCM5) LDTP03681 0.11  LDD0286 
DNA replication licensing factor MCM7 (MCM7) LDTP03682 1.27  LDD0286 
Dual specificity protein phosphatase 23 (DUSP23) LDTP11289 0.66  LDD0286 
Dual specificity protein phosphatase 3 (DUSP3) LDTP04415 0.88  LDD0286 
Dynamin-1-like protein (DNM1L) LDTP00273 0.52  LDD0286 
E3 ubiquitin-protein ligase ARIH2 (ARIH2) LDTP01575 0.85  LDD0286 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 1.05  LDD0286 
E3 ubiquitin-protein ligase UBR4 (UBR4) LDTP07118 0.26  LDD0286 
EH domain-containing protein 4 (EHD4) LDTP11788 0.60  LDD0286 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 1.07; 0.41; 0.75 ...  LDD0286 
Elongation factor 2 (EEF2) LDTP02672 1.11; 1.00; 0.83 ...  LDD0286 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 0.87; 0.98; 0.54  LDD0286 
Endoplasmic reticulum chaperone BiP (HSPA5) LDTP02534 4.78; 1.12; 2.80 ...  LDD0286 
Enoyl-CoA hydratase, mitochondrial (ECHS1) LDTP03518 0.76  LDD0286 
ERO1-like protein alpha (ERO1A) LDTP10386 1.02  LDD0286 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 1.20; 0.79; 1.01 ...  LDD0286 
Eukaryotic initiation factor 4A-III (EIF4A3) LDTP03861 0.61  LDD0286 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 2.27  LDD0286 
Exosome complex exonuclease RRP44 (DIS3) LDTP13887 0.65  LDD0286 
Farnesyl pyrophosphate synthase (FDPS) LDTP02721 0.80  LDD0286 
Fatty acid CoA ligase Acsl3 (ACSL3) LDTP01634 1.41; 0.63  LDD0286 
Fatty acid synthase (FASN) LDTP04243 1.01; 0.36; 0.84 ...  LDD0286 
Flap endonuclease 1 (FEN1) LDTP03872 0.60  LDD0286 
Fructose-2,6-bisphosphatase TIGAR (TIGAR) LDTP12405 0.59  LDD0286 
Fructose-bisphosphate aldolase A (ALDOA) LDTP02008 0.39; 0.57; 0.77 ...  LDD0286 
Fumarate hydratase, mitochondrial (FH) LDTP02235 0.52  LDD0286 
Fumarylacetoacetase (FAH) LDTP02868 0.44  LDD0286 
Galactokinase (GALK1) LDTP04424 0.61  LDD0286 
Gamma-enolase (ENO2) LDTP02328 0.73; 0.76  LDD0286 
GDP-mannose 4,6 dehydratase (GMDS) LDTP00999 0.83  LDD0286 
Geranylgeranyl transferase type-2 subunit beta (RABGGTB) LDTP04569 0.98  LDD0286 
Glucosamine-6-phosphate isomerase 1 (GNPDA1) LDTP04113 1.28  LDD0286 
Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 1.37; 0.74  LDD0286 
Glucose-6-phosphate isomerase (GPI) LDTP02162 0.58; 0.44; 1.69  LDD0286 
Glutaminase kidney isoform, mitochondrial (GLS) LDTP01465 0.35  LDD0286 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) LDTP05481 0.79; 0.45  LDD0286 
Glutaredoxin-1 (GLRX) LDTP03786 0.96  LDD0286 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 0.77; 0.27  LDD0286 
Glutathione S-transferase A4 (GSTA4) LDTP00575 1.01  LDD0286 
Glutathione S-transferase kappa 1 (GSTK1) LDTP13900 0.91  LDD0286 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 1.22  LDD0286 
Glutathione S-transferase P (GSTP1) LDTP02333 0.26; 0.61; 0.76 ...  LDD0286 
Glutathione synthetase (GSS) LDTP04200 0.80  LDD0286 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 0.47; 0.46; 0.47 ...  LDD0286 
Glycine--tRNA ligase (GARS1) LDTP03946 0.26; 2.94; 0.69  LDD0286 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 0.68; 0.73; 0.81 ...  LDD0286 
Glycogen phosphorylase, liver form (PYGL) LDTP02161 0.47  LDD0286 
Glycogen synthase kinase-3 alpha (GSK3A) LDTP04318 1.96  LDD0286 
Glycogen synthase kinase-3 beta (GSK3B) LDTP04319 1.96  LDD0286 
GTP-binding nuclear protein Ran (RAN) LDTP05007 0.36; 1.09; 0.45 ...  LDD0286 
HBS1-like protein (HBS1L) LDTP14019 0.57  LDD0286 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 0.93; 0.77; 0.78 ...  LDD0286 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 0.76; 1.08; 0.37 ...  LDD0286 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 1.47  LDD0286 
Histone deacetylase 1 (HDAC1) LDTP05918 0.53  LDD0286 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 0.56  LDD0286 
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL) LDTP03794 1.16  LDD0286 
Inorganic pyrophosphatase (PPA1) LDTP14854 1.04; 1.52; 0.78  LDD0286 
Inorganic pyrophosphatase 2, mitochondrial (PPA2) LDTP11842 0.78  LDD0286 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 1.31; 0.91; 0.63 ...  LDD0286 
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) LDTP11700 1.22  LDD0286 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 0.50; 1.32; 0.31  LDD0286 
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A) LDTP04345 0.09  LDD0286 
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (IDH3B) LDTP00885 0.37  LDD0286 
Kynurenine--oxoglutarate transaminase 3 (KYAT3) LDTP07763 0.26; 1.80  LDD0286 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 0.69; 1.01; 1.31 ...  LDD0286 
L-lactate dehydrogenase B chain (LDHB) LDTP02179 0.51; 0.89; 0.44 ...  LDD0286 
L-xylulose reductase (DCXR) LDTP08082 1.46  LDD0286 
Lactoylglutathione lyase (GLO1) LDTP05434 0.93  LDD0286 
Leucine--tRNA ligase, cytoplasmic (LARS1) LDTP13056 0.70  LDD0286 
Low molecular weight phosphotyrosine protein phosphatase (ACP1) LDTP03289 0.94; 0.93; 2.34  LDD0286 
Lymphokine-activated killer T-cell-originated protein kinase (PBK) LDTP10500 0.38; 0.66; 0.85  LDD0286 
Lysosomal protective protein (CTSA) LDTP02505 1.33  LDD0286 
Macrophage migration inhibitory factor (MIF) LDTP02713 0.34; 0.30; 0.25  LDD0286 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 0.52; 0.59  LDD0286 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 0.86; 1.15; 0.56 ...  LDD0286 
Mannose-1-phosphate guanyltransferase beta (GMPPB) LDTP14141 0.57  LDD0286 
MAP kinase-activated protein kinase 3 (MAPKAPK3) LDTP06589 0.63; 0.86  LDD0286 
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) LDTP02565 1.16; 1.76; 0.45 ...  LDD0286 
Methionine adenosyltransferase 2 subunit beta (MAT2B) LDTP12915 1.92  LDD0286 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 0.86  LDD0286 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 1.22  LDD0286 
Methylmalonyl-CoA mutase, mitochondrial (MMUT) LDTP03150 0.65  LDD0286 
Methylthioribulose-1-phosphate dehydratase (APIP) LDTP10368 0.95  LDD0286 
Mitochondrial-processing peptidase subunit beta (PMPCB) LDTP01220 3.83  LDD0286 
Mitogen-activated protein kinase 1 (MAPK1) LDTP03445 1.91; 1.00  LDD0286 
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) LDTP01005 0.96; 0.79  LDD0286 
Myosin-10 (MYH10) LDTP03765 0.59; 1.17; 0.94 ...  LDD0286 
Myosin-9 (MYH9) LDTP03764 0.92; 1.53; 0.48 ...  LDD0286 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 0.83  LDD0286 
NAD(P)H dehydrogenase [quinone] 1 (NQO1) LDTP02798 0.72; 1.50; 0.62 ...  LDD0286 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 0.77  LDD0286 
NEDD8-activating enzyme E1 regulatory subunit (NAE1) LDTP05925 1.38  LDD0286 
NEDD8-conjugating enzyme Ubc12 (UBE2M) LDTP04898 2.55  LDD0286 
Neutral alpha-glucosidase AB (GANAB) LDTP06192 1.65; 2.38  LDD0286 
Nucleoside diphosphate kinase B (NME2) LDTP03169 1.79  LDD0286 
Omega-amidase NIT2 (NIT2) LDTP12428 0.49; 0.92; 1.25 ...  LDD0286 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 1.20; 1.00; 0.52  LDD0286 
Palmitoyltransferase ZDHHC17 (ZDHHC17) LDTP08456 0.31  LDD0286 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 1.19; 0.69  LDD0286 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 1.45  LDD0286 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 0.56; 0.65  LDD0286 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 0.54; 1.27; 0.56  LDD0286 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) LDTP05912 1.00  LDD0286 
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3) LDTP11823 0.88  LDD0286 
Peroxiredoxin-1 (PRDX1) LDTP05503 1.12; 1.44; 1.68  LDD0286 
Peroxiredoxin-4 (PRDX4) LDTP05773 0.72; 1.51  LDD0286 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 0.41  LDD0286 
Phosphatidylinositide phosphatase SAC2 (INPP5F) LDTP13867 0.56  LDD0286 
Phosphoglucomutase-1 (PGM1) LDTP03818 0.89  LDD0286 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 0.73; 0.94; 0.44 ...  LDD0286 
Phosphoglycerate mutase 1 (PGAM1) LDTP02963 0.63; 1.48; 0.58 ...  LDD0286 
Phosphoserine aminotransferase (PSAT1) LDTP14198 0.19; 0.49; 1.64 ...  LDD0286 
Poly(A) polymerase alpha (PAPOLA) LDTP04394 0.43  LDD0286 
Presequence protease, mitochondrial (PITRM1) LDTP07003 0.29  LDD0286 
Probable 18S rRNA (guanine-N(7))-methyltransferase (BUD23) LDTP00845 1.29  LDD0286 
Probable aminopeptidase NPEPL1 (NPEPL1) LDTP09126 1.28  LDD0286 
Probable E3 ubiquitin-protein ligase IRF2BPL (IRF2BPL) LDTP11759 1.12; 0.99  LDD0286 
Prolyl endopeptidase (PREP) LDTP04163 1.20  LDD0286 
Prostaglandin reductase 1 (PTGR1) LDTP06227 0.52; 0.72  LDD0286 
Prostaglandin reductase 2 (PTGR2) LDTP08979 0.90; 1.35; 1.49  LDD0286 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 0.65; 1.68  LDD0286 
Proteasome subunit alpha type-2 (PSMA2) LDTP03331 0.81; 0.68; 1.01  LDD0286 
Proteasome subunit alpha type-3 (PSMA3) LDTP03332 0.42  LDD0286 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 0.76; 1.11; 0.74 ...  LDD0286 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 0.59; 0.78; 0.42 ...  LDD0286 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 0.54; 0.60  LDD0286 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 0.38; 0.30  LDD0286 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 0.17  LDD0286 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 0.52; 0.57  LDD0286 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 0.75; 0.57  LDD0286 
Protein arginine N-methyltransferase 5 (PRMT5) LDTP00418 0.84  LDD0286 
Protein disulfide-isomerase (P4HB) LDTP02188 1.11; 0.53; 1.31 ...  LDD0286 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 0.86; 0.69; 0.70 ...  LDD0286 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 1.50; 1.27; 1.65  LDD0286 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 0.85  LDD0286 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 0.62  LDD0286 
Protein kinase C delta type (PRKCD) LDTP05461 0.66  LDD0286 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 0.41  LDD0286 
Putative elongation factor 1-alpha-like 3 (EEF1A1P5) LDTP15029 1.07; 0.41; 0.74 ...  LDD0286 
Pyridoxine-5'-phosphate oxidase (PNPO) LDTP12691 0.82  LDD0286 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 0.87; 0.05  LDD0286 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 1.68; 1.79; 1.50 ...  LDD0286 
Pyruvate kinase PKM (PKM) LDTP02733 0.57; 0.96; 0.93 ...  LDD0286 
Queuine tRNA-ribosyltransferase catalytic subunit 1 (QTRT1) LDTP11400 0.47  LDD0286 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 0.70; 0.51  LDD0286 
RAC-gamma serine/threonine-protein kinase (AKT3) LDTP13799 0.77; 0.51  LDD0286 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 0.38; 0.54  LDD0286 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 0.53  LDD0286 
Ribonucleoside-diphosphate reductase large subunit (RRM1) LDTP03259 1.42  LDD0286 
RING finger and CHY zinc finger domain-containing protein 1 (RCHY1) LDTP10686 0.75  LDD0286 
RNA demethylase ALKBH5 (ALKBH5) LDTP07547 1.03  LDD0286 
RuvB-like 1 (RUVBL1) LDTP13816 0.79  LDD0286 
S-adenosylmethionine synthase isoform type-2 (MAT2A) LDTP03577 1.09; 0.42  LDD0286 
S-formylglutathione hydrolase (ESD) LDTP02521 0.83; 0.72  LDD0286 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 0.20  LDD0286 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 0.92  LDD0286 
Sepiapterin reductase (SPR) LDTP03730 1.23; 0.52  LDD0286 
Septin-2 (SEPTIN2) LDTP06279 0.38; 0.54  LDD0286 
Septin-7 (SEPTIN7) LDTP06513 0.72; 0.82  LDD0286 
Septin-9 (SEPTIN9) LDTP13272 0.11; 0.97; 1.36  LDD0286 
Serine hydroxymethyltransferase, cytosolic (SHMT1) LDTP03688 0.59  LDD0286 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 0.76  LDD0286 
Serine/threonine-protein kinase PAK 2 (PAK2) LDTP05776 0.71  LDD0286 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 1.16  LDD0286 
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) LDTP05064 0.54  LDD0286 
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB) LDTP04998 0.50  LDD0286 
Serine/threonine-protein phosphatase 4 catalytic subunit (PPP4C) LDTP04870 0.54  LDD0286 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 0.97  LDD0286 
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) LDTP04959 0.54; 0.77  LDD0286 
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) LDTP04960 0.54; 0.77  LDD0286 
Sialic acid synthase (NANS) LDTP12473 0.40; 0.58; 0.74  LDD0286 
Spermidine synthase (SRM) LDTP03008 1.13  LDD0286 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 0.63; 0.78  LDD0286 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 0.40  LDD0286 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 1.29  LDD0286 
SUMO-activating enzyme subunit 2 (UBA2) LDTP13156 0.43; 0.56  LDD0286 
SUMO-conjugating enzyme UBC9 (UBE2I) LDTP05062 0.40  LDD0286 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 0.84; 0.63; 1.88  LDD0286 
Thimet oligopeptidase (THOP1) LDTP04542 0.53  LDD0286 
Thioredoxin domain-containing protein 12 (TXNDC12) LDTP01707 0.91  LDD0286 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 0.89; 0.75; 0.72 ...  LDD0286 
Threonine--tRNA ligase 1, cytoplasmic (TARS1) LDTP03365 1.03; 0.86; 0.50 ...  LDD0286 
Thymidylate kinase (DTYMK) LDTP03258 0.58  LDD0286 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 0.41; 0.73; 0.81 ...  LDD0286 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 0.68  LDD0286 
Transketolase (TKT) LDTP03487 0.40; 0.45; 0.93 ...  LDD0286 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 0.95  LDD0286 
Triosephosphate isomerase (TPI1) LDTP04851 0.38; 1.98; 0.62  LDD0286 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 1.34  LDD0286 
Tryptophan--tRNA ligase, cytoplasmic (WARS1) LDTP03222 0.46; 0.19; 0.86  LDD0286 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 0.60; 0.59; 0.60 ...  LDD0286 
Tubulin alpha-1B chain (TUBA1B) LDTP05074 0.60; 0.59; 0.60 ...  LDD0286 
Tubulin alpha-1C chain (TUBA1C) LDTP11074 0.61  LDD0286 
Tubulin--tyrosine ligase-like protein 12 (TTLL12) LDTP06067 0.32; 0.05  LDD0286 
Tyrosine--tRNA ligase, cytoplasmic (YARS1) LDTP04617 1.70; 1.23  LDD0286 
Tyrosine-protein kinase CSK (CSK) LDTP03944 0.55  LDD0286 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 1.78  LDD0286 
Ubiquitin carboxyl-terminal hydrolase 14 (USP14) LDTP04618 0.88; 0.27  LDD0286 
Ubiquitin carboxyl-terminal hydrolase 39 (USP39) LDTP06903 1.34  LDD0286 
Ubiquitin carboxyl-terminal hydrolase 4 (USP4) LDTP05749 1.10  LDD0286 
Ubiquitin-conjugating enzyme E2 N (UBE2N) LDTP04900 0.86; 4.59; 0.52  LDD0286 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 0.54; 0.34; 0.74 ...  LDD0286 
UDP-glucose 4-epimerase (GALE) LDTP06111 0.75  LDD0286 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 0.84; 0.36; 0.78 ...  LDD0286 
UMP-CMP kinase (CMPK1) LDTP03519 0.60  LDD0286 
Uridine 5'-monophosphate synthase (UMPS) LDTP02548 0.62  LDD0286 
Uridine phosphorylase 1 (UPP1) LDTP06643 0.71; 1.24; 0.78 ...  LDD0286 
Uroporphyrinogen decarboxylase (UROD) LDTP02135 1.36; 0.66  LDD0286 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 1.37; 1.26; 1.13  LDD0286 
V-type proton ATPase subunit E 2 (ATP6V1E2) LDTP15684 0.87  LDD0286 
Valine--tRNA ligase (VARS1) LDTP03366 0.85  LDD0286 
WD repeat-containing protein 82 (WDR82) LDTP07715 0.68  LDD0286 
Xaa-Pro aminopeptidase 1 (XPNPEP1) LDTP12444 0.98; 1.01  LDD0286 
------------------------------------------------------------------------------------
⏷ Show the Full List of 293 Enzyme
40 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein epsilon (YWHAE) LDTP04969 1.35; 0.55; 0.32 ...  LDD0286 
14-3-3 protein gamma (YWHAG) LDTP04953 1.27  LDD0286 
14-3-3 protein theta (YWHAQ) LDTP03385 1.11; 1.12  LDD0286 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 0.39; 0.57; 1.44 ...  LDD0286 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 0.62; 0.66  LDD0286 
Alpha-crystallin B chain (CRYAB) LDTP01929 0.93  LDD0286 
Alpha-synuclein (SNCA) LDTP03848 2.85  LDD0286 
Annexin A2 (ANXA2) LDTP02199 1.31; 1.02; 1.10 ...  LDD0286 
Annexin A5 (ANXA5) LDTP02307 0.60; 0.44; 0.65 ...  LDD0286 
Annexin A6 (ANXA6) LDTP02247 0.36; 0.75  LDD0286 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 0.68  LDD0286 
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 1.42; 0.82  LDD0286 
Calreticulin (CALR) LDTP03402 0.69; 0.53; 0.99 ...  LDD0286 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 1.16; 0.34; 0.30 ...  LDD0286 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 0.96; 1.37; 0.83  LDD0286 
Clathrin heavy chain 1 (CLTC) LDTP05252 0.82; 0.91  LDD0286 
Copine-3 (CPNE3) LDTP01133 0.83; 0.80  LDD0286 
Cystatin-B (CSTB) LDTP02009 0.79; 0.42; 0.85  LDD0286 
Dihydropyrimidinase-related protein 2 (DPYSL2) LDTP06554 1.73; 0.81; 0.40  LDD0286 
Eukaryotic translation initiation factor 5A-1 (EIF5A) LDTP05056 0.62; 0.96  LDD0286 
Exportin-1 (XPO1) LDTP00501 0.54; 0.65  LDD0286 
Exportin-2 (CSE1L) LDTP04662 0.39  LDD0286 
Filamin-A (FLNA) LDTP03107 1.48; 0.98  LDD0286 
Galectin-3 (LGALS3) LDTP02929 0.40  LDD0286 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 1.27; 0.32; 1.58 ...  LDD0286 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 0.42  LDD0286 
Importin subunit beta-1 (KPNB1) LDTP06242 0.57; 20.00  LDD0286 
mRNA export factor RAE1 (RAE1) LDTP05122 0.62  LDD0286 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 0.66; 0.38  LDD0286 
T-complex protein 1 subunit delta (CCT4) LDTP04391 0.78; 0.81; 1.18 ...  LDD0286 
Talin-1 (TLN1) LDTP14031 1.45; 0.78; 0.71 ...  LDD0286 
Thioredoxin domain-containing protein 17 (TXNDC17) LDTP11103 0.39; 1.68; 0.62  LDD0286 
Transferrin receptor protein 1 (TFRC) LDTP01969 2.15  LDD0286 
Ubiquilin-4 (UBQLN4) LDTP12533 0.65  LDD0286 
V-type proton ATPase subunit B, brain isoform (ATP6V1B2) LDTP03104 0.51; 0.77  LDD0286 
V-type proton ATPase subunit C 1 (ATP6V1C1) LDTP03105 0.69  LDD0286 
V-type proton ATPase subunit E 1 (ATP6V1E1) LDTP03811 0.87  LDD0286 
V-type proton ATPase subunit G 1 (ATP6V1G1) LDTP01185 0.86  LDD0286 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 0.55  LDD0286 
Voltage-gated potassium channel subunit beta-2 (KCNAB2) LDTP05817 0.66  LDD0286 
------------------------------------------------------------------------------------
⏷ Show the Full List of 40 Transporter and channel
7 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
High mobility group protein B1 (HMGB1) LDTP02343 0.51; 1.60; 0.68 ...  LDD0286 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 0.46  LDD0286 
Signal transducer and activator of transcription 3 (STAT3) LDTP03903 3.72  LDD0286 
Signal transducer and activator of transcription 5A (STAT5A) LDTP03971 0.74  LDD0286 
Transcription factor SOX-10 (SOX10) LDTP04752 1.62; 0.44  LDD0286 
Transcription factor SOX-9 (SOX9) LDTP04179 1.33  LDD0286 
Y-box-binding protein 1 (YBX1) LDTP05065 1.58; 1.58; 1.00  LDD0286 
------------------------------------------------------------------------------------
⏷ Show the Full List of 7 Transcription factor
280 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
10 kDa heat shock protein, mitochondrial (HSPE1) LDTP04931 3.27  LDD0286 
14-3-3 protein beta/alpha (YWHAB) LDTP03617 0.42; 0.35  LDD0286 
14-3-3 protein eta (YWHAH) LDTP05442 0.78  LDD0286 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 1.02  LDD0286 
55 kDa erythrocyte membrane protein (MPP1) LDTP05233 2.07  LDD0286 
Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) LDTP03871 1.17  LDD0286 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 0.38  LDD0286 
Actin nucleation-promoting factor WASL (WASL) LDTP00263 0.89  LDD0286 
Actin-related protein 3 (ACTR3) LDTP04902 0.73; 0.70; 0.36 ...  LDD0286 
Adapter molecule crk (CRK) LDTP04091 0.91; 0.60; 1.25  LDD0286 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 0.28; 0.56; 1.00  LDD0286 
AH receptor-interacting protein (AIP) LDTP00202 0.76  LDD0286 
Alpha-actinin-1 (ACTN1) LDTP02631 0.24; 0.79; 1.08  LDD0286 
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) LDTP05770 0.53  LDD0286 
Anamorsin (CIAPIN1) LDTP07385 0.48  LDD0286 
Ankyrin repeat and MYND domain-containing protein 2 (ANKMY2) LDTP17620 1.23  LDD0286 
Ankyrin repeat domain-containing protein 39 (ANKRD39) LDTP19320 0.60  LDD0286 
Annexin A3 (ANXA3) LDTP02620 1.02  LDD0286 
Annexin A7 (ANXA7) LDTP03030 0.67  LDD0286 
Apoptosis inhibitor 5 (API5) LDTP11575 0.66  LDD0286 
Beta-parvin (PARVB) LDTP12184 2.38  LDD0286 
Bifunctional purine biosynthesis protein ATIC (ATIC) LDTP03612 0.70; 0.61; 0.60 ...  LDD0286 
Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (ARFGEF2) LDTP14237 1.24  LDD0286 
C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9) LDTP00934 0.65; 0.63  LDD0286 
Calpain small subunit 1 (CAPNS1) LDTP02047 0.77  LDD0286 
Calponin-3 (CNN3) LDTP06383 0.66; 0.57; 0.70 ...  LDD0286 
Calumenin (CALU) LDTP00887 0.55; 0.61; 0.68 ...  LDD0286 
cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) LDTP02697 1.11  LDD0286 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 0.82; 0.91; 1.36 ...  LDD0286 
Cell cycle and apoptosis regulator protein 2 (CCAR2) LDTP08760 1.31  LDD0286 
Coatomer subunit beta (COPB1) LDTP04570 0.69  LDD0286 
Coatomer subunit gamma-1 (COPG1) LDTP14216 0.64  LDD0286 
Cofilin-1 (CFL1) LDTP03244 0.77; 0.85; 1.27 ...  LDD0286 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 1.25  LDD0286 
Condensin complex subunit 2 (NCAPH) LDTP06268 0.90  LDD0286 
Copper transport protein ATOX1 (ATOX1) LDTP00229 1.06  LDD0286 
Coronin-1B (CORO1B) LDTP11101 0.88  LDD0286 
Coronin-1C (CORO1C) LDTP13580 0.65  LDD0286 
Crk-like protein (CRKL) LDTP04092 0.95; 0.48  LDD0286 
Cysteine and glycine-rich protein 1 (CSRP1) LDTP03106 1.11; 0.51; 1.63  LDD0286 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 0.85; 1.23; 1.10 ...  LDD0286 
Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2) LDTP05855 0.81  LDD0286 
Cytoplasmic FMR1-interacting protein 1 (CYFIP1) LDTP07958 0.79  LDD0286 
Cytotoxic granule associated RNA binding protein TIA1 (TIA1) LDTP03598 0.80  LDD0286 
Destrin (DSTN) LDTP04887 0.61; 0.87; 0.56  LDD0286 
DnaJ homolog subfamily A member 2 (DNAJA2) LDTP01073 1.25  LDD0286 
DnaJ homolog subfamily B member 1 (DNAJB1) LDTP03325 0.59  LDD0286 
DnaJ homolog subfamily C member 3 (DNAJC3) LDTP05789 1.20  LDD0286 
DnaJ homolog subfamily C member 8 (DNAJC8) LDTP01361 1.05  LDD0286 
Drebrin-like protein (DBNL) LDTP13399 0.83; 0.71; 0.90  LDD0286 
Dynactin subunit 1 (DCTN1) LDTP06082 0.47  LDD0286 
Dynactin subunit 2 (DCTN2) LDTP05922 1.26  LDD0286 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 0.91  LDD0286 
Dynein light chain 2, cytoplasmic (DYNLL2) LDTP10308 1.04  LDD0286 
Elongation factor 1-beta (EEF1B2) LDTP03283 0.78; 0.61; 0.76 ...  LDD0286 
Elongation factor 1-delta (EEF1D) LDTP03499 0.57; 0.90; 0.92 ...  LDD0286 
Elongation factor 1-gamma (EEF1G) LDTP03367 0.43; 0.25; 0.80  LDD0286 
Endoplasmic reticulum resident protein 29 (ERP29) LDTP03509 0.84; 0.88  LDD0286 
Endoplasmin (HSP90B1) LDTP02734 0.45; 0.60; 1.10 ...  LDD0286 
Enhancer of mRNA-decapping protein 3 (EDC3) LDTP10299 0.49  LDD0286 
Epidermal growth factor receptor substrate 15-like 1 (EPS15L1) LDTP13097 0.81  LDD0286 
Eukaryotic translation initiation factor 1 (EIF1) LDTP03953 0.70  LDD0286 
Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX) LDTP04129 0.87  LDD0286 
Eukaryotic translation initiation factor 1b (EIF1B) LDTP16815 0.70  LDD0286 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 0.65  LDD0286 
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) LDTP03027 0.40  LDD0286 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 1.58  LDD0286 
Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 0.61  LDD0286 
Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 1.02  LDD0286 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 1.79  LDD0286 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 0.68; 1.78  LDD0286 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 1.46  LDD0286 
Eukaryotic translation initiation factor 4H (EIF4H) LDTP06301 0.34  LDD0286 
F-actin-uncapping protein LRRC16A (CARMIL1) LDTP07261 0.61  LDD0286 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 1.84; 0.98; 2.36  LDD0286 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 0.76; 0.78; 0.61 ...  LDD0286 
Gelsolin (GSN) LDTP02145 0.34; 0.57; 0.27 ...  LDD0286 
General transcription factor IIF subunit 2 (GTF2F2) LDTP02703 0.71; 0.69  LDD0286 
Growth factor receptor-bound protein 2 (GRB2) LDTP05035 0.90  LDD0286 
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPVD1) LDTP06255 1.40  LDD0286 
Heat shock 70 kDa protein 1A (HSPA1A) LDTP02434 0.93; 0.74; 1.71 ...  LDD0286 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 0.63; 0.76; 2.06 ...  LDD0286 
Heat shock 70 kDa protein 4L (HSPA4L) LDTP14545 0.91  LDD0286 
Heat shock protein 105 kDa (HSPH1) LDTP09811 0.61; 0.34  LDD0286 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 1.69  LDD0286 
Heat shock protein beta-1 (HSPB1) LDTP02053 0.87; 0.52; 0.55 ...  LDD0286 
Heme-binding protein 1 (HEBP1) LDTP16078 1.03; 0.41  LDD0286 
Hepatoma-derived growth factor (HDGF) LDTP04483 0.43  LDD0286 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 0.59; 0.58  LDD0286 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 0.89; 0.67; 0.70 ...  LDD0286 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 0.56; 0.65; 0.65  LDD0286 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 0.70  LDD0286 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 0.99; 0.58; 0.66 ...  LDD0286 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 1.02; 0.85; 0.52 ...  LDD0286 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 0.54; 0.81; 0.54 ...  LDD0286 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 0.56  LDD0286 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 2.65  LDD0286 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 0.65; 0.63; 0.46 ...  LDD0286 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 0.69; 0.77; 1.83 ...  LDD0286 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 0.39  LDD0286 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 0.76; 0.61; 0.57 ...  LDD0286 
Histone H2B type 1-D (H2BC5) LDTP04822 1.06; 0.61; 1.16  LDD0286 
Histone H2B type 1-L (H2BC13) LDTP11001 1.16  LDD0286 
Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) LDTP05004 3.70; 1.53  LDD0286 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 1.62; 0.85  LDD0286 
Hsc70-interacting protein (ST13) LDTP04367 0.98; 0.64; 1.34  LDD0286 
Influenza virus NS1A-binding protein (IVNS1ABP) LDTP14309 0.56  LDD0286 
Integrator complex subunit 10 (INTS10) LDTP16111 0.69  LDD0286 
IST1 homolog (IST1) LDTP04593 0.67  LDD0286 
Kinesin light chain 1 (KLC1) LDTP05533 0.28; 0.70  LDD0286 
Kinesin light chain 2 (KLC2) LDTP11695 0.28; 0.70  LDD0286 
Laminin subunit beta-2 (LAMB2) LDTP04691 2.35  LDD0286 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 0.90  LDD0286 
Large ribosomal subunit protein eL21 (RPL21) LDTP04107 0.76; 0.47; 0.73  LDD0286 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 0.78; 0.66  LDD0286 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 0.78; 0.89  LDD0286 
Large ribosomal subunit protein eL29 (RPL29) LDTP04140 0.86  LDD0286 
Large ribosomal subunit protein eL31 (RPL31) LDTP05023 1.45  LDD0286 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 0.63  LDD0286 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 0.60  LDD0286 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 0.66  LDD0286 
Large ribosomal subunit protein eL37 (RPL37) LDTP04943 0.82  LDD0286 
Large ribosomal subunit protein eL43 (RPL37A) LDTP04926 0.50  LDD0286 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 0.35  LDD0286 
Large ribosomal subunit protein uL13 (RPL13A) LDTP03899 0.75; 0.54  LDD0286 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 0.50  LDD0286 
Large ribosomal subunit protein uL16 (RPL10) LDTP03395 0.40  LDD0286 
Large ribosomal subunit protein uL18 (RPL5) LDTP04106 1.83  LDD0286 
Large ribosomal subunit protein uL2 (RPL8) LDTP05027 0.65  LDD0286 
Large ribosomal subunit protein uL22 (RPL17) LDTP02961 0.47  LDD0286 
Large ribosomal subunit protein uL29 (RPL35) LDTP03999 0.62  LDD0286 
Large ribosomal subunit protein uL30 (RPL7) LDTP02944 0.45  LDD0286 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 0.30; 0.17; 0.67 ...  LDD0286 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 0.92; 0.97  LDD0286 
LIM domain and actin-binding protein 1 (LIMA1) LDTP13260 1.44  LDD0286 
LRP chaperone MESD (MESD) LDTP06191 0.38  LDD0286 
Macrophage-capping protein (CAPG) LDTP03877 1.14; 0.48  LDD0286 
Microtubule-associated protein 4 (MAP4) LDTP03404 0.96  LDD0286 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 0.59  LDD0286 
Muscleblind-like protein 1 (MBNL1) LDTP12478 0.82; 0.61  LDD0286 
Muscleblind-like protein 2 (MBNL2) LDTP07260 0.82  LDD0286 
Muscleblind-like protein 3 (MBNL3) LDTP12630 0.61  LDD0286 
Myeloid-derived growth factor (MYDGF) LDTP10003 2.64  LDD0286 
Myosin light polypeptide 6 (MYL6) LDTP04875 1.54; 1.96  LDD0286 
Myosin regulatory light chain 12B (MYL12B) LDTP00487 0.16; 0.91  LDD0286 
N6-adenosine-methyltransferase non-catalytic subunit (METTL14) LDTP12234 0.67  LDD0286 
Nascent polypeptide-associated complex subunit alpha (NACA) LDTP05977 0.86  LDD0286 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 0.49; 0.55  LDD0286 
Nuclear migration protein nudC (NUDC) LDTP13817 0.91  LDD0286 
Nucleolin (NCL) LDTP02990 1.55; 0.95; 0.79 ...  LDD0286 
Nucleolysin TIAR (TIAL1) LDTP05274 1.38  LDD0286 
Nucleophosmin (NPM1) LDTP02164 0.84; 0.93; 0.51  LDD0286 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 0.51; 1.60; 0.47  LDD0286 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 0.58; 0.47  LDD0286 
Oxysterol-binding protein-related protein 11 (OSBPL11) LDTP11367 1.20  LDD0286 
Perilipin-3 (PLIN3) LDTP01021 0.69  LDD0286 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 0.17; 1.03; 2.07 ...  LDD0286 
Plastin-3 (PLS3) LDTP02692 0.49  LDD0286 
Platelet-activating factor acetylhydrolase IB subunit beta (PAFAH1B1) LDTP04015 1.05; 1.37  LDD0286 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 0.81; 0.79; 0.81  LDD0286 
Poly(rC)-binding protein 2 (PCBP2) LDTP06367 0.56; 1.17  LDD0286 
Polyadenylate-binding protein 1 (PABPC1) LDTP02595 0.88; 0.65; 0.68 ...  LDD0286 
Polyadenylate-binding protein 4 (PABPC4) LDTP05821 0.74; 0.42  LDD0286 
Polypyrimidine tract-binding protein 1 (PTBP1) LDTP03364 0.84; 1.01  LDD0286 
Prefoldin subunit 3 (VBP1) LDTP04935 1.10  LDD0286 
Prelamin-A/C (LMNA) LDTP01932 0.93; 0.83  LDD0286 
Profilin-1 (PFN1) LDTP02218 0.73; 0.61  LDD0286 
Programmed cell death protein 5 (PDCD5) LDTP00417 1.54; 1.86  LDD0286 
Proliferating cell nuclear antigen (PCNA) LDTP02596 1.11; 0.83  LDD0286 
Protein BUD31 homolog (BUD31) LDTP03935 0.32  LDD0286 
Protein FAM118B (FAM118B) LDTP15852 1.37  LDD0286 
Protein flightless-1 homolog (FLII) LDTP05734 0.64  LDD0286 
Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) LDTP13656 0.97; 0.92; 0.87 ...  LDD0286 
Protein LSM12 (LSM12) LDTP06780 2.36  LDD0286 
Protein mago nashi homolog 2 (MAGOHB) LDTP10071 0.81  LDD0286 
Protein NipSnap homolog 3A (NIPSNAP3A) LDTP18525 1.86; 1.68  LDD0286 
Protein phosphatase 1 regulatory subunit 12A (PPP1R12A) LDTP00495 2.04  LDD0286 
Protein RCC2 (RCC2) LDTP13020 0.91  LDD0286 
Protein S100-A11 (S100A11) LDTP03620 0.94; 1.19  LDD0286 
Protein SET (SET) LDTP05277 3.31  LDD0286 
Protein SGT1 homolog (SUGT1) LDTP13935 0.63; 1.05  LDD0286 
Protein TFG (TFG) LDTP09851 0.86  LDD0286 
Protein transport protein Sec23A (SEC23A) LDTP06390 0.09; 0.61  LDD0286 
Protein transport protein Sec23B (SEC23B) LDTP06391 0.75  LDD0286 
Protein UXT (UXT) LDTP13125 0.77  LDD0286 
Protein VAC14 homolog (VAC14) LDTP05586 0.18  LDD0286 
Putative protein FAM10A5 (ST13P5) LDTP17811 1.34  LDD0286 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 0.56  LDD0286 
Pyridoxal phosphate homeostasis protein (PLPBP) LDTP14521 1.43  LDD0286 
Rab GDP dissociation inhibitor alpha (GDI1) LDTP03574 0.76; 0.63  LDD0286 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 0.72; 0.62; 0.27 ...  LDD0286 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 1.39  LDD0286 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 0.81; 0.41; 0.07 ...  LDD0286 
Reticulocalbin-1 (RCN1) LDTP06352 1.39  LDD0286 
Retinoblastoma-associated protein (RB1) LDTP02146 0.77  LDD0286 
Rho GDP-dissociation inhibitor 1 (ARHGDIA) LDTP04510 0.50; 1.09; 1.57 ...  LDD0286 
Rho guanine nucleotide exchange factor 2 (ARHGEF2) LDTP09950 0.48  LDD0286 
Ribosome biogenesis protein WDR12 (WDR12) LDTP11625 1.27  LDD0286 
RNA-binding protein 3 (RBM3) LDTP05226 0.57; 0.54  LDD0286 
RNA-binding protein EWS (EWSR1) LDTP05318 0.57  LDD0286 
RNA-binding protein FUS (FUS) LDTP03775 1.47; 0.83  LDD0286 
Serine/arginine-rich splicing factor 2 (SRSF2) LDTP05280 0.65  LDD0286 
Serine/arginine-rich splicing factor 8 (SRSF8) LDTP11117 0.65  LDD0286 
Serpin H1 (SERPINH1) LDTP04363 0.95  LDD0286 
Single-stranded DNA-binding protein, mitochondrial (SSBP1) LDTP05437 0.99; 1.63; 0.99 ...  LDD0286 
Small acidic protein (SMAP) LDTP19007 0.65  LDD0286 
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) LDTP00862 0.90; 0.37; 0.73 ...  LDD0286 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 0.65; 0.44; 0.52  LDD0286 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 0.95; 0.51  LDD0286 
Small ribosomal subunit protein eS19 (RPS19) LDTP03864 0.51  LDD0286 
Small ribosomal subunit protein eS24 (RPS24) LDTP05012 0.86; 1.12; 0.67  LDD0286 
Small ribosomal subunit protein eS26 (RPS26) LDTP05014 0.35  LDD0286 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 0.65; 0.78  LDD0286 
Small ribosomal subunit protein eS4, Y isoform 1 (RPS4Y1) LDTP14653 0.78  LDD0286 
Small ribosomal subunit protein eS4, Y isoform 2 (RPS4Y2) LDTP19820 0.78  LDD0286 
Small ribosomal subunit protein eS7 (RPS7) LDTP04958 0.45  LDD0286 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 0.89; 0.61; 2.54 ...  LDD0286 
Small ribosomal subunit protein uS11 (RPS14) LDTP04970 0.40  LDD0286 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 0.32  LDD0286 
Small ribosomal subunit protein uS13 (RPS18) LDTP04972 0.74; 0.76; 0.78  LDD0286 
Small ribosomal subunit protein uS15 (RPS13) LDTP04974 0.69; 0.92; 0.77  LDD0286 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 0.53; 1.09  LDD0286 
Small ribosomal subunit protein uS2 (RPSA) LDTP02312 0.47  LDD0286 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 0.60; 0.96; 0.53  LDD0286 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 0.50; 0.76  LDD0286 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 1.37; 0.84  LDD0286 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 0.68  LDD0286 
Splicing factor YJU2 (YJU2) LDTP11317 0.70  LDD0286 
Src substrate cortactin (CTTN) LDTP06094 0.76; 0.82; 0.78 ...  LDD0286 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 1.18; 0.99; 0.89 ...  LDD0286 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 0.50; 0.13; 0.59 ...  LDD0286 
Stromal cell-derived factor 2-like protein 1 (SDF2L1) LDTP16047 1.01  LDD0286 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 0.91; 1.33  LDD0286 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 1.37  LDD0286 
Structural maintenance of chromosomes protein 4 (SMC4) LDTP12606 0.47  LDD0286 
T-complex protein 1 subunit beta (CCT2) LDTP05113 1.27; 0.87; 20.00  LDD0286 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 0.72; 0.82  LDD0286 
T-complex protein 1 subunit eta (CCT7) LDTP10990 0.45  LDD0286 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 1.13; 0.66  LDD0286 
T-complex protein 1 subunit theta (CCT8) LDTP04390 0.59; 1.20; 0.83 ...  LDD0286 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 0.35  LDD0286 
T-complex protein 1 subunit zeta-2 (CCT6B) LDTP09777 0.35  LDD0286 
Tetratricopeptide repeat protein 1 (TTC1) LDTP15840 1.81  LDD0286 
Tetratricopeptide repeat protein 4 (TTC4) LDTP01678 0.59  LDD0286 
Transcription elongation factor A protein 1 (TCEA1) LDTP03209 0.49  LDD0286 
Transcription elongation factor SPT6 (SUPT6H) LDTP07928 0.90  LDD0286 
Transgelin-2 (TAGLN2) LDTP03846 0.61; 0.79; 0.78  LDD0286 
Translation initiation factor eIF2B subunit delta (EIF2B4) LDTP13318 9.97  LDD0286 
Translationally-controlled tumor protein (TPT1) LDTP02683 0.60  LDD0286 
Transmembrane glycoprotein NMB (GPNMB) LDTP06237 1.50  LDD0286 
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WDR6) LDTP12296 0.68  LDD0286 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 0.88  LDD0286 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 0.98  LDD0286 
Tubulin beta chain (TUBB) LDTP02205 0.58; 0.91; 0.66 ...  LDD0286 
Tubulin beta-2A chain (TUBB2A) LDTP05998 20.00; 0.19; 0.75 ...  LDD0286 
Tubulin beta-2B chain (TUBB2B) LDTP11277 0.94; 0.75; 0.63 ...  LDD0286 
Tubulin beta-3 chain (TUBB3) LDTP05904 0.58; 0.77; 1.81 ...  LDD0286 
Tubulin beta-4A chain (TUBB4A) LDTP02037 0.57; 0.61; 1.32 ...  LDD0286 
Tubulin beta-4B chain (TUBB4B) LDTP05076 0.85; 0.65; 0.59 ...  LDD0286 
Tubulin beta-6 chain (TUBB6) LDTP11233 0.75; 0.54; 0.19 ...  LDD0286 
Tubulin gamma-1 chain (TUBG1) LDTP03213 0.33  LDD0286 
Tubulin gamma-2 chain (TUBG2) LDTP12512 0.33  LDD0286 
Tubulin-folding cofactor B (TBCB) LDTP10860 0.95; 0.89  LDD0286 
U6 snRNA-associated Sm-like protein LSm2 (LSM2) LDTP13946 1.64  LDD0286 
Ubiquilin-1 (UBQLN1) LDTP13626 0.66  LDD0286 
Ubiquitin-associated protein 2-like (UBAP2L) LDTP06060 3.36; 0.55  LDD0286 
Ubiquitin-fold modifier 1 (UFM1) LDTP04946 1.30  LDD0286 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 1.03  LDD0286 
Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) LDTP11534 0.73  LDD0286 
Vacuolar fusion protein CCZ1 homolog (CCZ1) LDTP14797 0.59  LDD0286 
Vacuolar protein sorting-associated protein VTA1 homolog (VTA1) LDTP12317 0.24  LDD0286 
Vasodilator-stimulated phosphoprotein (VASP) LDTP04372 1.00  LDD0286 
Vimentin (VIM) LDTP02297 1.35; 0.79; 0.54 ...  LDD0286 
Vinculin (VCL) LDTP02946 1.21; 1.19  LDD0286 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 0.82  LDD0286 
WD repeat-containing protein 1 (WDR1) LDTP01118 1.17; 0.51; 0.37 ...  LDD0286 
WD repeat-containing protein 5 (WDR5) LDTP04948 1.33  LDD0286 
WW domain-binding protein 2 (WBP2) LDTP10033 0.44; 0.52; 0.67 ...  LDD0286 
Zinc finger CCHC domain-containing protein 8 (ZCCHC8) LDTP07496 0.21  LDD0286 
Zyxin (ZYX) LDTP06507 0.98; 0.62  LDD0286 
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Full Information of The Labelling Profiles of This Competitor

HHS-482
 Probe Info 
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 50 uM
Quantitative Method SILAC
Competitor Name JWB142
Competitor Concentration 50 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Skin
Disease Model Melanoma [ICD-11:2C82]
Model Name Human melanoma cell lysate (DM93)
Interaction Atlas ID  LDD0286  Download The Altas

References

1 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.